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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Nkx2-4

Z-value: 0.51

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Transcription factors associated with Nkx2-4

Gene Symbol Gene ID Gene Info
Nkx2-4
ENSRNOG00000012647 NK2 homeobox 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nkx2-4rn6_v1_chr3_-_141305471_141305471-0.035.8e-01Click!

Activity profile of Nkx2-4 motif

Sorted Z-values of Nkx2-4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_76789298 13.39 ENSRNOT00000077853
AABR07018857.1

chr7_+_136182224 12.72 ENSRNOT00000008159
Tmem117
transmembrane protein 117
chr14_-_85191557 10.21 ENSRNOT00000011604
Nefh
neurofilament heavy
chr15_-_14737704 9.54 ENSRNOT00000011307
Synpr
synaptoporin
chr1_-_224698514 8.81 ENSRNOT00000024234
Slc22a25
solute carrier family 22, member 25
chr2_+_144861455 8.71 ENSRNOT00000093284
ENSRNOT00000019748
ENSRNOT00000072110
Dclk1
doublecortin-like kinase 1
chr2_-_235177275 8.06 ENSRNOT00000093153
LOC103691699
uncharacterized LOC103691699
chr4_+_64088900 7.57 ENSRNOT00000075341
Chrm2
cholinergic receptor, muscarinic 2
chr5_+_149077412 7.51 ENSRNOT00000014666
Matn1
matrilin 1, cartilage matrix protein
chr2_+_68820615 7.51 ENSRNOT00000087007
ENSRNOT00000089504
Egf
epidermal growth factor
chr2_+_68821004 7.43 ENSRNOT00000083713
Egf
epidermal growth factor
chr9_+_47281961 7.04 ENSRNOT00000065234
Slc9a4
solute carrier family 9 member A4
chr9_-_28732919 6.56 ENSRNOT00000083915
Rims1
regulating synaptic membrane exocytosis 1
chr17_-_61332391 6.46 ENSRNOT00000034599
LOC100362965
SNRPN upstream reading frame protein-like
chr7_+_123510804 6.38 ENSRNOT00000010491
Sept3
septin 3
chr6_+_43001948 6.27 ENSRNOT00000007374
Hpcal1
hippocalcin-like 1
chr14_+_113867209 6.10 ENSRNOT00000067591
Ccdc88a
coiled coil domain containing 88A
chr4_-_49422824 5.93 ENSRNOT00000077889
Fam3c
family with sequence similarity 3, member C
chr18_+_29972808 5.54 ENSRNOT00000074051
Pcdha4
protocadherin alpha 4
chr1_+_100161872 5.35 ENSRNOT00000025777
Klk1c3
kallikrein 1-related peptidase C3
chr18_+_29993361 4.75 ENSRNOT00000075810
Pcdha4
protocadherin alpha 4
chr1_-_100671074 4.73 ENSRNOT00000027132
Myh14
myosin heavy chain 14
chr16_-_82099991 4.15 ENSRNOT00000089447
Atp11a
ATPase phospholipid transporting 11A
chr14_-_14390699 4.14 ENSRNOT00000046639
Anxa3
annexin A3
chr16_-_55132191 4.06 ENSRNOT00000017025
Micu3
mitochondrial calcium uptake family, member 3
chr9_+_82596355 3.80 ENSRNOT00000065076
Speg
SPEG complex locus
chr5_+_78384444 3.44 ENSRNOT00000034978
LOC500475
similar to hypothetical protein 4933430I17
chr1_+_101688297 3.33 ENSRNOT00000091606
Dbp
D-box binding PAR bZIP transcription factor
chr8_-_55162421 3.17 ENSRNOT00000083102
Dixdc1
DIX domain containing 1
chr3_-_9936352 3.11 ENSRNOT00000011224
ENSRNOT00000042798
Fnbp1
formin binding protein 1
chr2_+_72006099 2.92 ENSRNOT00000034044
Cdh12
cadherin 12
chr10_-_66858598 2.90 ENSRNOT00000018898
Evi2b
ecotropic viral integration site 2B
chr4_-_160662974 2.86 ENSRNOT00000089199
Tspan9
tetraspanin 9
chr2_+_95320283 2.71 ENSRNOT00000015537
Hey1
hes-related family bHLH transcription factor with YRPW motif 1
chr19_-_10358695 2.69 ENSRNOT00000019770
Katnb1
katanin regulatory subunit B1
chr3_-_141411170 2.65 ENSRNOT00000017364
Nkx2-2
NK2 homeobox 2
chr8_+_107508351 2.61 ENSRNOT00000081594
Cep70
centrosomal protein 70
chr15_-_60289763 2.61 ENSRNOT00000038579
Fam216b
family with sequence similarity 216, member B
chr4_-_22425381 2.45 ENSRNOT00000011166
ENSRNOT00000037712
Abcb1a
ATP binding cassette subfamily B member 1A
chr4_-_129430251 2.41 ENSRNOT00000067881
Fam19a4
family with sequence similarity 19 member A4, C-C motif chemokine like
chr18_-_63394690 2.33 ENSRNOT00000090078
ENSRNOT00000029431
Cep76
centrosomal protein 76
chr3_+_19495628 2.28 ENSRNOT00000077990
Igkv4-57
immunoglobulin kappa variable 4-57
chr3_+_2396143 2.19 ENSRNOT00000012388
Nrarp
Notch-regulated ankyrin repeat protein
chr3_-_93216495 2.08 ENSRNOT00000010580
Ehf
ets homologous factor
chr17_-_29895386 2.05 ENSRNOT00000048757
Cdyl
chromodomain Y-like
chr1_-_67134827 2.01 ENSRNOT00000045214
Vom1r45
vomeronasal 1 receptor 45
chr19_+_57047830 1.90 ENSRNOT00000080860
Galnt2
polypeptide N-acetylgalactosaminyltransferase 2
chr4_-_155421998 1.78 ENSRNOT00000041552
Gdf3
growth differentiation factor 3
chr2_+_22910236 1.77 ENSRNOT00000078266
Homer1
homer scaffolding protein 1
chr15_-_14510828 1.71 ENSRNOT00000039347
Sntn
sentan, cilia apical structure protein
chr3_+_19690016 1.69 ENSRNOT00000085460
AABR07051707.1

chr14_+_72889038 1.59 ENSRNOT00000084261
Rab5a
RAB5A, member RAS oncogene family
chr16_-_8564379 1.58 ENSRNOT00000060975
LOC680885
hypothetical protein LOC680885
chr1_-_242765807 1.42 ENSRNOT00000020763
Pgm5
phosphoglucomutase 5
chr10_-_19574094 1.40 ENSRNOT00000059810
Dock2
dedicator of cytokinesis 2
chr5_-_139853247 1.35 ENSRNOT00000056644
Exo5
exonuclease 5
chr1_-_82004538 1.31 ENSRNOT00000087572
Pou2f2
POU class 2 homeobox 2
chr14_-_74095146 1.30 ENSRNOT00000049313
LOC679766
similar to developmental pluripotency-associated 3
chr4_+_120672152 1.28 ENSRNOT00000077231
Mgll
monoglyceride lipase
chr12_-_13133219 1.26 ENSRNOT00000092292
Daglb
diacylglycerol lipase, beta
chr7_-_9104719 1.16 ENSRNOT00000088247
LOC103692758
olfactory receptor 6C74-like
chr4_+_82783686 1.15 ENSRNOT00000041988
Tax1bp1
Tax1 binding protein 1
chr20_-_5227620 1.14 ENSRNOT00000086240
RT1-DMb
RT1 class II, locus DMb
chr4_-_68819872 1.03 ENSRNOT00000033265
ENSRNOT00000081884
Clec5a
C-type lectin domain family 5, member A
chr12_-_19114399 0.96 ENSRNOT00000073099
Cyp3a9
cytochrome P450, family 3, subfamily a, polypeptide 9
chr3_-_173944396 0.95 ENSRNOT00000079019
Sycp2
synaptonemal complex protein 2
chr14_-_107160334 0.86 ENSRNOT00000012131
Ehbp1
EH domain binding protein 1
chr10_-_70646495 0.80 ENSRNOT00000071218
Gas2l2
growth arrest-specific 2 like 2
chr1_-_155955173 0.79 ENSRNOT00000079345
AABR07004776.1

chr9_-_17163170 0.73 ENSRNOT00000025921
Xpo5
exportin 5
chr6_+_10306405 0.67 ENSRNOT00000090420
ENSRNOT00000080507
Epas1
endothelial PAS domain protein 1
chr8_+_1502877 0.67 ENSRNOT00000034482
Msantd4
Myb/SANT DNA binding domain containing 4 with coiled-coils
chr10_+_90984227 0.65 ENSRNOT00000003890
ENSRNOT00000093707
Ccdc103
coiled-coil domain containing 103
chr8_+_96551245 0.63 ENSRNOT00000039850
Bcl2a1
BCL2-related protein A1
chr2_-_240866689 0.58 ENSRNOT00000036838
Nfkb1
nuclear factor kappa B subunit 1
chr7_+_107467260 0.50 ENSRNOT00000009240
ENSRNOT00000077382
Tg
thyroglobulin
chr2_-_213178632 0.44 ENSRNOT00000023079
LOC108348173
protein arginine N-methyltransferase 6
chr1_+_60248695 0.31 ENSRNOT00000079558
Vom1r9
vomeronasal 1 receptor 9
chr8_-_20173107 0.30 ENSRNOT00000045215
Olr1163
olfactory receptor 1163
chr13_-_26769374 0.27 ENSRNOT00000003768
Bcl2
BCL2, apoptosis regulator
chr1_+_170147300 0.26 ENSRNOT00000048075
Olr200
olfactory receptor 200
chr3_-_74567685 0.25 ENSRNOT00000068048
Olr532
olfactory receptor 532
chr1_+_75233703 0.24 ENSRNOT00000064178
LOC100911727
DNA ligase 1-like
chr7_-_130170609 0.20 ENSRNOT00000088030
Dennd6b
DENN domain containing 6B
chr20_+_1736377 0.17 ENSRNOT00000047035
Olr1734
olfactory receptor 1734
chr3_+_18805220 0.17 ENSRNOT00000071216
Igkv4-86
immunoglobulin kappa variable 4-86
chr6_+_136084605 0.14 ENSRNOT00000092806
Mark3
microtubule affinity regulating kinase 3
chr5_+_118418799 0.12 ENSRNOT00000012052
Alg6
ALG6, alpha-1,3-glucosyltransferase
chr1_-_44615760 0.09 ENSRNOT00000022148
Nox3
NADPH oxidase 3
chr7_+_140742418 0.06 ENSRNOT00000089211
Prph
peripherin
chr1_-_48686713 0.03 ENSRNOT00000091196
AABR07001516.1

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx2-4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.2 GO:0033693 neurofilament bundle assembly(GO:0033693)
2.2 6.6 GO:0031632 positive regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031632)
2.0 6.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
1.9 14.9 GO:0007262 STAT protein import into nucleus(GO:0007262)
1.5 7.6 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
1.1 7.5 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418)
0.9 2.7 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.9 2.7 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.9 2.7 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.8 8.8 GO:0015747 urate transport(GO:0015747)
0.6 2.5 GO:1905235 carbohydrate export(GO:0033231) daunorubicin transport(GO:0043215) response to borneol(GO:1905230) cellular response to borneol(GO:1905231) response to codeine(GO:1905233) response to quercetin(GO:1905235) drug transport across blood-brain barrier(GO:1990962) establishment of blood-retinal barrier(GO:1990963)
0.5 7.0 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.5 1.6 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.5 1.9 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.5 3.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.4 1.3 GO:0002380 immunoglobulin secretion involved in immune response(GO:0002380)
0.3 1.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.3 1.1 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.3 4.0 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.3 4.1 GO:0043312 neutrophil degranulation(GO:0043312)
0.2 0.7 GO:1900368 regulation of RNA interference(GO:1900368)
0.2 1.0 GO:0009822 lipid hydroxylation(GO:0002933) alkaloid catabolic process(GO:0009822)
0.2 8.7 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.2 0.6 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.2 1.4 GO:0019388 galactose catabolic process(GO:0019388)
0.2 1.4 GO:0001767 establishment of lymphocyte polarity(GO:0001767) establishment of T cell polarity(GO:0001768)
0.2 4.1 GO:0045332 phospholipid translocation(GO:0045332)
0.2 1.0 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.2 4.7 GO:0071625 vocalization behavior(GO:0071625)
0.1 2.3 GO:0046599 regulation of centriole replication(GO:0046599)
0.1 0.7 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 1.8 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.3 GO:0006808 regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 1.4 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 1.3 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.1 0.7 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.1 0.5 GO:0015705 iodide transport(GO:0015705)
0.0 1.0 GO:0002076 osteoblast development(GO:0002076)
0.0 7.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 2.4 GO:0051931 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 0.2 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.0 0.8 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.1 GO:0048840 otolith development(GO:0048840)
0.0 1.2 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 2.1 GO:0016573 histone acetylation(GO:0016573)
0.0 3.3 GO:0007623 circadian rhythm(GO:0007623)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.6 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
1.3 6.4 GO:0099569 presynaptic cytoskeleton(GO:0099569)
1.3 7.6 GO:0032280 symmetric synapse(GO:0032280)
1.2 4.7 GO:0097513 myosin II filament(GO:0097513)
0.9 10.2 GO:0097418 neurofibrillary tangle(GO:0097418)
0.5 1.6 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.4 9.5 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.4 2.9 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 4.1 GO:0042581 specific granule(GO:0042581)
0.2 2.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 0.7 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.1 1.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 8.4 GO:0005814 centriole(GO:0005814)
0.1 0.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 1.3 GO:0043196 varicosity(GO:0043196)
0.0 1.8 GO:0043034 costamere(GO:0043034)
0.0 2.7 GO:0044450 microtubule organizing center part(GO:0044450)
0.0 3.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.0 GO:0000800 lateral element(GO:0000800)
0.0 14.9 GO:0043235 receptor complex(GO:0043235)
0.0 7.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 4.3 GO:0055037 recycling endosome(GO:0055037)
0.0 3.2 GO:0043679 axon terminus(GO:0043679)
0.0 5.4 GO:0014069 postsynaptic density(GO:0014069)
0.0 10.3 GO:0045202 synapse(GO:0045202)
0.0 0.8 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 4.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0046930 pore complex(GO:0046930)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.6 GO:1990763 arrestin family protein binding(GO:1990763)
0.9 2.7 GO:0035939 microsatellite binding(GO:0035939)
0.9 8.8 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.9 14.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.8 4.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.7 7.0 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.5 10.2 GO:0015643 toxic substance binding(GO:0015643)
0.5 2.5 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.4 1.8 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.3 4.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.3 6.1 GO:0043422 protein kinase B binding(GO:0043422)
0.3 1.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 4.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 1.4 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.2 1.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2 2.7 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 0.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 1.6 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.1 1.4 GO:0042608 T cell receptor binding(GO:0042608)
0.1 3.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 7.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 3.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 1.1 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.9 GO:0051400 BH domain binding(GO:0051400)
0.1 0.7 GO:0050897 cobalt ion binding(GO:0050897)
0.1 1.0 GO:0001618 virus receptor activity(GO:0001618)
0.0 6.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.0 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 2.1 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.8 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.7 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.2 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 5.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 14.7 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.7 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 6.4 GO:0005525 GTP binding(GO:0005525)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 6.8 GO:0004674 protein serine/threonine kinase activity(GO:0004674)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 14.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 2.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.6 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 7.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 5.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.9 PID BCR 5PATHWAY BCR signaling pathway
0.0 2.3 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 14.9 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.5 6.6 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2 7.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 4.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 2.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 4.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 3.3 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 4.9 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 7.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 2.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.7 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.4 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 1.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production