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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Nfil3_Tef

Z-value: 1.93

Motif logo

Transcription factors associated with Nfil3_Tef

Gene Symbol Gene ID Gene Info
ENSRNOG00000011668 nuclear factor, interleukin 3 regulated
ENSRNOG00000019383 TEF, PAR bZIP transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tefrn6_v1_chr7_+_123043503_1230435840.395.2e-13Click!
Nfil3rn6_v1_chr17_+_12261102_122611020.283.8e-07Click!

Activity profile of Nfil3_Tef motif

Sorted Z-values of Nfil3_Tef motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_73529612 164.17 ENSRNOT00000032430
unc-80 homolog, NALCN activator
chr14_-_19191863 121.38 ENSRNOT00000003921
albumin
chr17_+_41798783 113.30 ENSRNOT00000023519
neurensin 1
chr1_+_248428099 106.32 ENSRNOT00000050984
mannose binding lectin 2
chr5_+_120340646 105.83 ENSRNOT00000086259
ENSRNOT00000086539
DnaJ heat shock protein family (Hsp40) member C6
chr4_-_85915099 104.03 ENSRNOT00000016182
neuronal differentiation 6
chr3_+_95715193 95.12 ENSRNOT00000089525
paired box 6
chr1_-_256813711 90.05 ENSRNOT00000021055
retinol binding protein 4
chr5_-_130085838 82.25 ENSRNOT00000035252
ELAV like RNA binding protein 4
chr2_-_41784929 82.11 ENSRNOT00000086851
RAB3C, member RAS oncogene family
chr1_+_224800252 80.37 ENSRNOT00000024488
solute carrier family 22 member 8
chr11_-_81639872 78.97 ENSRNOT00000047595
ENSRNOT00000090031
ENSRNOT00000081864
histidine-rich glycoprotein
chr3_-_44086006 77.31 ENSRNOT00000034449
ENSRNOT00000082604
ermin
chr15_+_40665041 63.26 ENSRNOT00000018300
APC membrane recruitment protein 2
chr8_-_94563760 60.69 ENSRNOT00000032792
synaptosomal-associated protein 91
chr12_-_29743705 57.76 ENSRNOT00000001185
calneuron 1
chr11_+_57505005 57.22 ENSRNOT00000002942
transgelin-3
chr11_+_60072727 56.36 ENSRNOT00000090230
transgelin 3
chr9_-_82461903 54.28 ENSRNOT00000026654
protein tyrosine phosphatase, receptor type, N
chr10_-_90030639 52.17 ENSRNOT00000090456
membrane palmitoylated protein 2
chr9_+_73378057 48.57 ENSRNOT00000043627
ENSRNOT00000045766
ENSRNOT00000092445
ENSRNOT00000037974
microtubule-associated protein 2
chr17_-_43537293 47.75 ENSRNOT00000091749
solute carrier family 17 member 3
chr2_-_35104963 47.40 ENSRNOT00000018058
regulator of G-protein signaling 7-binding protein
chr18_-_26211445 46.40 ENSRNOT00000027739
neuronal regeneration related protein
chrX_-_10218583 46.14 ENSRNOT00000013382
nyctalopin
chr1_+_229039889 45.42 ENSRNOT00000054800
glycine-N-acyltransferase-like 1
chr1_+_250426158 43.30 ENSRNOT00000067643
APOBEC1 complementation factor
chr1_+_15642153 41.71 ENSRNOT00000079845
microtubule-associated protein 7
chr1_+_84470829 41.66 ENSRNOT00000025472
tetratricopeptide repeat domain 9B
chr14_-_3300200 40.54 ENSRNOT00000037931
BTB (POZ) domain containing 8
chr11_+_42259761 40.52 ENSRNOT00000047310
Eph receptor A6
chr3_+_129018592 40.20 ENSRNOT00000007274
lysosomal-associated membrane protein family, member 5
chr4_-_161850875 39.78 ENSRNOT00000009467
pregnancy-zone protein
chr16_-_45929 37.73 ENSRNOT00000043153

chr9_-_8632017 37.02 ENSRNOT00000043269

chr14_+_66598259 36.85 ENSRNOT00000049743
potassium voltage-gated channel interacting protein 4
chr11_+_62584959 35.63 ENSRNOT00000071065
GRAM domain containing 1C
chr11_-_81660395 35.25 ENSRNOT00000048739
fetuin B
chr1_-_67065797 35.14 ENSRNOT00000048152
vomeronasal 1 receptor 46
chr16_+_66380173 34.66 ENSRNOT00000048862
similar to Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg)
chr9_+_117538346 34.61 ENSRNOT00000022849
erythrocyte membrane protein band 4.1-like 3
chr16_+_66230011 34.56 ENSRNOT00000074550
similar to Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg)
chr16_+_18690246 34.33 ENSRNOT00000081484
methionine adenosyltransferase 1A
chr2_+_198321142 34.09 ENSRNOT00000028760
synaptic vesicle glycoprotein 2a
chr9_+_12475006 34.02 ENSRNOT00000079703
uncharacterized LOC100912293
chrX_+_33884499 33.61 ENSRNOT00000090041
RALBP1 associated Eps domain containing protein 2
chr1_+_217345545 33.27 ENSRNOT00000071741
SH3 and multiple ankyrin repeat domains 2
chr16_+_66230841 32.91 ENSRNOT00000050464
similar to Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg)
chr9_-_9142339 32.80 ENSRNOT00000046852
similar to RIKEN cDNA 1700001E04
chr9_+_105943512 32.32 ENSRNOT00000046409
ENSRNOT00000075578
uncharacterized LOC100912293
chr9_-_464390 32.23 ENSRNOT00000051066
similar to RIKEN cDNA 1700001E04
chr10_-_90030423 32.04 ENSRNOT00000092150
membrane palmitoylated protein 2
chrX_+_9436707 31.92 ENSRNOT00000004187
calcium/calmodulin dependent serine protein kinase
chr1_+_27476375 31.71 ENSRNOT00000047224
ENSRNOT00000075427
sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2-like
chr1_+_83163079 31.70 ENSRNOT00000077725
ENSRNOT00000034845
cytochrome P450, family 2, subfamily b, polypeptide 3
chr20_+_10930518 31.36 ENSRNOT00000001589
pyridoxal (pyridoxine, vitamin B6) kinase
chr1_+_217345154 30.62 ENSRNOT00000092516
SH3 and multiple ankyrin repeat domains 2
chr4_-_11610518 30.54 ENSRNOT00000066643
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr9_-_9143189 30.14 ENSRNOT00000089904
similar to RIKEN cDNA 1700001E04
chr4_-_176528110 30.07 ENSRNOT00000049569
solute carrier organic anion transporter family, member 1A2
chr1_+_28454966 30.03 ENSRNOT00000078841
ENSRNOT00000030327
tumor protein D52-like 1
chr2_+_22000106 29.32 ENSRNOT00000061812
ankyrin repeat domain 34B
chr2_+_252771017 28.47 ENSRNOT00000075452
ENSRNOT00000055318
tubulin tyrosine ligase like 7
chr5_-_58163584 27.55 ENSRNOT00000060594
C-C motif chemokine ligand 27
chrX_+_22788660 27.48 ENSRNOT00000071886

chr11_+_20474483 27.20 ENSRNOT00000082417
ENSRNOT00000002895
neural cell adhesion molecule 2
chr3_+_177310753 26.17 ENSRNOT00000031448
myelin transcription factor 1
chr19_+_15294248 26.01 ENSRNOT00000024622
carboxylesterase 1F
chr6_+_48452369 25.92 ENSRNOT00000044310
myelin transcription factor 1-like
chr2_-_216443518 25.28 ENSRNOT00000022496
amylase, alpha 1A
chr13_-_82753438 24.38 ENSRNOT00000075948
ATPase Na+/K+ transporting subunit beta 1
chr17_+_8489266 24.30 ENSRNOT00000016252
leukocyte cell-derived chemotaxin 2
chr3_-_138683318 23.97 ENSRNOT00000029701
double zinc ribbon and ankyrin repeat domains 1
chr18_+_81821127 23.89 ENSRNOT00000058199
F-box protein 15
chr20_-_54517709 23.77 ENSRNOT00000076234
glutamate ionotropic receptor kainate type subunit 2
chr7_+_110031696 23.40 ENSRNOT00000012753
KH RNA binding domain containing, signal transduction associated 3
chr13_-_111972603 23.25 ENSRNOT00000007870
hydroxysteroid 11-beta dehydrogenase 1
chr9_-_19749145 23.12 ENSRNOT00000013956
regulator of calcineurin 2
chr14_-_46153212 23.06 ENSRNOT00000079269
NACHT and WD repeat domain containing 2
chr3_+_124515978 22.88 ENSRNOT00000028881
prion protein
chr1_-_258875572 22.65 ENSRNOT00000093005
cytochrome P450, family 2, subfamily c, polypeptide 13
chr11_-_81717521 22.64 ENSRNOT00000058422
alpha-2-HS-glycoprotein
chr4_-_68597586 22.62 ENSRNOT00000015921
similar to RIKEN cDNA E330009J07 gene
chr9_+_25410669 22.11 ENSRNOT00000030912
ENSRNOT00000090920
transcription factor AP-2 beta
chr1_-_67206713 22.08 ENSRNOT00000048195
vomeronasal 1 receptor 43
chr2_-_197991574 21.64 ENSRNOT00000085632
circadian associated repressor of transcription
chr15_-_47442664 21.50 ENSRNOT00000072994
protease, serine, 55
chr1_+_147713892 21.10 ENSRNOT00000092985
ENSRNOT00000054742
ENSRNOT00000074103
cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1
chr4_+_110699557 20.63 ENSRNOT00000030588
ENSRNOT00000092261
leucine rich repeat transmembrane neuronal 4
chr6_-_14523961 20.18 ENSRNOT00000071402
neurexin 1
chr1_-_279277339 19.80 ENSRNOT00000023667
GDNF family receptor alpha 1
chr1_-_143535583 19.72 ENSRNOT00000087785
homer scaffolding protein 2
chr1_-_261669584 19.71 ENSRNOT00000020568
ENSRNOT00000076555
cartilage acidic protein 1
chr5_+_58661049 19.69 ENSRNOT00000078274
unc-13 homolog B
chr1_+_219759183 19.33 ENSRNOT00000026316
pyruvate carboxylase
chr18_+_31444472 19.19 ENSRNOT00000075159
ring finger protein 14
chr4_+_110700403 18.69 ENSRNOT00000092379
leucine rich repeat transmembrane neuronal 4
chr12_-_35979193 18.48 ENSRNOT00000071104
transmembrane protein 132B
chr17_-_2278613 18.10 ENSRNOT00000046525
contactin associated protein-like 3B
chr12_+_18679789 18.06 ENSRNOT00000001863
cytochrome P450, family 3, subfamily a, polypeptide 9
chr11_+_88732381 17.80 ENSRNOT00000078367
FYVE, RhoGEF and PH domain containing 4
chr2_+_248649441 17.52 ENSRNOT00000067165
kynurenine aminotransferase 3
chr5_+_107369730 17.20 ENSRNOT00000046837
interferon alpha-1-like
chr20_-_15334745 16.92 ENSRNOT00000067633
protocadherin 15
chr13_-_57080491 16.57 ENSRNOT00000017749
ENSRNOT00000086572
ENSRNOT00000060111
complement factor H
chr2_-_184263564 16.46 ENSRNOT00000015279
F-box and WD repeat domain containing 7
chrX_-_138972684 16.30 ENSRNOT00000040165
heparan sulfate 6-O-sulfotransferase 2
chr1_-_3763392 16.23 ENSRNOT00000034744
sterile alpha motif domain containing 5
chr5_-_160742479 16.00 ENSRNOT00000019447
kazrin, periplakin interacting protein
chr2_+_247248407 15.94 ENSRNOT00000082287
unc-5 netrin receptor C
chr10_-_58693754 15.25 ENSRNOT00000071764
PITPNM family member 3
chr2_+_184230459 14.93 ENSRNOT00000074187

chr2_+_3662763 14.91 ENSRNOT00000017828
multiple C2 and transmembrane domain containing 1
chr7_+_120140460 14.76 ENSRNOT00000040513
ENSRNOT00000073905
pyridoxal phosphatase
chr2_-_57935334 14.47 ENSRNOT00000022319
ENSRNOT00000085599
ENSRNOT00000077790
ENSRNOT00000035821
solute carrier family 1 member 3
chr1_-_67175736 14.28 ENSRNOT00000046788
vomeronasal 1 receptor 44
chr2_+_150146234 14.16 ENSRNOT00000018761
arylacetamide deacetylase
chr12_+_18936594 13.83 ENSRNOT00000081587
sprouty RTK signaling antagonist 3
chr2_-_244335165 13.31 ENSRNOT00000084860
Rap1 GTPase-GDP dissociation stimulator 1
chr6_-_102047758 13.22 ENSRNOT00000012101
ATPase H+ transporting V1 subunit D
chr1_+_17602281 13.18 ENSRNOT00000075461
jouberin-like
chr18_+_29987206 12.69 ENSRNOT00000027383
protocadherin alpha 4
chr17_-_45154355 12.64 ENSRNOT00000084976
zinc finger with KRAB and SCAN domains 4
chrX_-_13116743 12.34 ENSRNOT00000004305
MID1 interacting protein 1
chr1_-_224698514 12.13 ENSRNOT00000024234
solute carrier family 22, member 25
chr7_+_73222730 12.12 ENSRNOT00000007816
glutamate-rich 5
chrX_+_70645270 11.63 ENSRNOT00000076456
discs large MAGUK scaffold protein 3
chr3_+_110669312 11.54 ENSRNOT00000013829
isovaleryl-CoA dehydrogenase
chr11_-_1983513 11.46 ENSRNOT00000000907
5-hydroxytryptamine receptor 1F
chr1_+_255185629 11.29 ENSRNOT00000083002
HECT domain E3 ubiquitin protein ligase 2
chr1_+_83103925 11.29 ENSRNOT00000047540
ENSRNOT00000028196
cytochrome P450, family 2, subfamily b, polypeptide 2
chr15_+_7871497 11.24 ENSRNOT00000046879
ubiquitin-conjugating enzyme E2E 2
chr1_+_156262031 11.23 ENSRNOT00000038279
transmembrane protein 126B
chr14_+_34446616 11.21 ENSRNOT00000002976
clock circadian regulator
chr18_+_30010918 11.17 ENSRNOT00000084132
protocadherin alpha 4
chr19_+_17290178 10.88 ENSRNOT00000060865
AKT interacting protein
chr3_-_57957346 10.70 ENSRNOT00000036728
solute carrier family 25 member 12
chr1_+_154579949 10.33 ENSRNOT00000045048
synaptotagmin-like 2
chr2_+_251200686 10.29 ENSRNOT00000019210
collagen type XXIV alpha 1 chain
chr7_-_7189599 10.16 ENSRNOT00000004458
olfactory receptor 1016
chr10_-_66873948 10.00 ENSRNOT00000039261
ecotropic viral integration site 2A
chr2_+_4252496 9.24 ENSRNOT00000071535
similar to KIAA0825 protein
chr3_-_146396299 9.23 ENSRNOT00000040188
ENSRNOT00000008931
adipocyte plasma membrane associated protein
chr4_+_167219728 9.05 ENSRNOT00000075273
small integral membrane protein 10 like 1
chr2_-_53300404 8.90 ENSRNOT00000088876
growth hormone receptor
chr20_+_11972381 8.89 ENSRNOT00000001642
adenosine deaminase, RNA-specific, B1
chr1_+_61095171 8.72 ENSRNOT00000042702
vomeronasal 1 receptor 19
chrX_+_20216587 8.50 ENSRNOT00000073114
FYVE, RhoGEF and PH domain-containing protein 1
chr18_+_30496318 8.49 ENSRNOT00000027179
protocadherin beta 11
chr3_-_21904133 8.39 ENSRNOT00000090576
ENSRNOT00000087611
ENSRNOT00000066377
spermatid perinuclear RNA binding protein
chr14_+_48740190 8.16 ENSRNOT00000031638
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr9_+_61655963 7.90 ENSRNOT00000040461
coenzyme Q10B
chr3_-_73879647 7.53 ENSRNOT00000090000
olfactory receptor 510
chr18_-_41389510 7.53 ENSRNOT00000005476
ENSRNOT00000005446
semaphorin 6A
chr13_-_104080631 7.49 ENSRNOT00000032865
lysophospholipase-like 1
chr1_-_141655417 7.47 ENSRNOT00000068084
adaptor-related protein complex 3, sigma 2 subunit
chr6_+_73358112 7.46 ENSRNOT00000041373
Rho GTPase activating protein 5
chr10_-_56289882 7.42 ENSRNOT00000090762
ENSRNOT00000056903
tumor necrosis factor superfamily member 13
chr5_+_58995249 7.41 ENSRNOT00000023411
coiled-coil domain containing 107
chr3_+_79729739 7.34 ENSRNOT00000084833
kelch repeat and BTB domain containing 4
chr16_+_54291251 6.89 ENSRNOT00000079006
microtubule associated tumor suppressor 1
chr1_+_167944448 6.78 ENSRNOT00000087667
olfactory receptor 56
chr9_+_16749809 6.57 ENSRNOT00000028786
cullin 9
chr12_+_8725517 6.54 ENSRNOT00000001243
solute carrier family 46, member 3
chr2_+_12516702 6.53 ENSRNOT00000050072
transmembrane protein 161B
chr10_-_94406949 6.51 ENSRNOT00000012533
coiled-coil domain containing 47
chr20_+_1781320 6.43 ENSRNOT00000040388
olfactory receptor 1737
chr13_+_44475970 6.41 ENSRNOT00000024602
ENSRNOT00000091645
cyclin T2
chrX_-_77559348 6.41 ENSRNOT00000047823
fibronectin type III domain containing 3C1
chr3_+_160092975 6.39 ENSRNOT00000080707
cAMP-dependent protein kinase inhibitor gamma
chr14_-_72970329 6.28 ENSRNOT00000006325
protein phosphatase 2C-like domain containing 1
chr8_+_82038967 6.24 ENSRNOT00000079535
myosin VA
chr1_-_62558033 6.19 ENSRNOT00000015520
zinc finger protein 40
chr9_-_66483614 6.14 ENSRNOT00000022047
small ubiquitin-like modifier 1
chr13_-_95348913 6.11 ENSRNOT00000057879
AKT serine/threonine kinase 3
chr7_-_6803318 6.10 ENSRNOT00000084203
olfactory receptor 954
chr16_-_14300951 5.96 ENSRNOT00000017038
retinal G protein coupled receptor
chr5_-_149987910 5.88 ENSRNOT00000091637
protein tyrosine phosphatase, receptor type, U
chr16_+_54332660 5.86 ENSRNOT00000037685
microtubule associated tumor suppressor 1
chr2_-_178297172 5.85 ENSRNOT00000038543
folliculin interacting protein 2
chr2_+_46203776 5.81 ENSRNOT00000074056
olfactory receptor 147-like
chr14_+_79261092 5.80 ENSRNOT00000029191
hypothetical protein LOC680039
chr7_+_130308532 5.68 ENSRNOT00000011941
myo-inositol oxygenase
chr1_+_240908483 5.62 ENSRNOT00000019367
Kruppel-like factor 9
chr5_-_153184940 5.52 ENSRNOT00000079536
transmembrane protein 57
chr4_+_22084954 5.51 ENSRNOT00000090968
carnitine O-octanoyltransferase
chr2_+_206314213 5.40 ENSRNOT00000056068
BCL2-like 15
chr1_-_43638161 5.15 ENSRNOT00000024460
interaction protein for cytohesin exchange factors 1
chr7_-_70407177 5.08 ENSRNOT00000049895
OS9, endoplasmic reticulum lectin
chr3_-_46361092 5.06 ENSRNOT00000008987
CD302 molecule
chr2_-_30634243 4.96 ENSRNOT00000077537
MARVEL domain containing 2
chr1_-_282235974 4.95 ENSRNOT00000054674
sideroflexin 4
chr7_-_117364697 4.94 ENSRNOT00000077314
5-oxoprolinase (ATP-hydrolysing)
chr3_-_75089064 4.86 ENSRNOT00000046167
olfactory receptor 542
chr3_+_93968855 4.81 ENSRNOT00000014478
F-box protein 3
chr6_-_89933168 4.78 ENSRNOT00000005511

chr10_-_44471915 4.64 ENSRNOT00000089901
olfactory receptor 1440
chr9_+_23596964 4.42 ENSRNOT00000064279
exocrine gland-secreted peptide 1-like
chr1_-_53038229 4.25 ENSRNOT00000017282
mitochondrial pyruvate carrier 1
chr1_-_22661377 4.21 ENSRNOT00000021896
vanin 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfil3_Tef

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
31.7 95.1 GO:0021917 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
30.0 90.1 GO:0046865 isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
26.8 80.4 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
26.6 106.3 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
26.5 105.8 GO:0072318 clathrin coat disassembly(GO:0072318)
26.3 79.0 GO:0097037 heme export(GO:0097037)
20.2 121.4 GO:0044004 killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004) response to platinum ion(GO:0070541)
15.4 46.1 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
10.8 43.3 GO:0016554 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) cytidine to uridine editing(GO:0016554)
8.7 60.7 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
8.1 24.4 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
7.8 23.3 GO:0006713 glucocorticoid catabolic process(GO:0006713)
7.6 22.9 GO:1900272 negative regulation of long-term synaptic potentiation(GO:1900272)
6.9 34.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
6.3 50.7 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
6.3 25.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
5.8 34.6 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205)
5.5 16.5 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
5.4 59.9 GO:0015747 urate transport(GO:0015747)
5.4 16.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
5.3 21.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)
4.9 63.9 GO:0098880 maintenance of postsynaptic specialization structure(GO:0098880) maintenance of postsynaptic density structure(GO:0099562)
4.8 19.3 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
4.6 27.6 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
4.5 104.0 GO:0021542 dentate gyrus development(GO:0021542)
4.5 18.1 GO:0009822 lipid hydroxylation(GO:0002933) alkaloid catabolic process(GO:0009822)
4.4 22.1 GO:0097070 ductus arteriosus closure(GO:0097070)
4.4 39.3 GO:0097113 AMPA glutamate receptor clustering(GO:0097113)
3.8 11.5 GO:0006552 leucine catabolic process(GO:0006552)
3.6 54.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
3.5 31.7 GO:0042738 exogenous drug catabolic process(GO:0042738)
3.5 17.5 GO:0097052 L-kynurenine metabolic process(GO:0097052)
3.0 8.9 GO:0061744 motor behavior(GO:0061744)
2.8 28.5 GO:0018095 protein polyglutamylation(GO:0018095)
2.8 19.7 GO:0099525 positive regulation of synaptic vesicle priming(GO:0010808) presynaptic dense core granule exocytosis(GO:0099525)
2.7 30.1 GO:0070327 thyroid hormone transport(GO:0070327)
2.7 15.9 GO:0033564 anterior/posterior axon guidance(GO:0033564)
2.5 17.8 GO:0030035 microspike assembly(GO:0030035)
2.5 37.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
2.5 7.4 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
2.4 26.2 GO:0060539 diaphragm development(GO:0060539)
2.2 11.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
2.1 6.4 GO:0019086 late viral transcription(GO:0019086)
2.1 34.1 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
2.0 41.7 GO:0033327 Leydig cell differentiation(GO:0033327)
1.9 11.3 GO:0009820 alkaloid metabolic process(GO:0009820)
1.9 16.9 GO:0050957 equilibrioception(GO:0050957)
1.9 7.5 GO:0002084 protein depalmitoylation(GO:0002084)
1.9 11.2 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
1.8 23.1 GO:0007614 short-term memory(GO:0007614)
1.6 63.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
1.6 46.9 GO:0007413 axonal fasciculation(GO:0007413)
1.6 6.2 GO:0051643 endoplasmic reticulum localization(GO:0051643)
1.5 9.2 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
1.5 6.1 GO:0090204 PML body organization(GO:0030578) protein localization to nuclear pore(GO:0090204) positive regulation of calcium-transporting ATPase activity(GO:1901896)
1.5 13.3 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
1.4 17.2 GO:0033139 regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
1.4 14.2 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
1.4 4.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
1.4 2.8 GO:0007172 signal complex assembly(GO:0007172)
1.4 102.0 GO:0042220 response to cocaine(GO:0042220)
1.3 84.2 GO:0060291 long-term synaptic potentiation(GO:0060291)
1.3 23.8 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
1.2 16.6 GO:0030449 regulation of complement activation(GO:0030449)
1.2 11.6 GO:0046710 GDP metabolic process(GO:0046710)
1.1 3.4 GO:0006116 NADH oxidation(GO:0006116)
1.1 42.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
1.1 5.5 GO:0001579 medium-chain fatty acid transport(GO:0001579)
1.0 4.1 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
1.0 35.2 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
1.0 3.0 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
1.0 8.9 GO:0000255 allantoin metabolic process(GO:0000255) creatine metabolic process(GO:0006600) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
1.0 22.6 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
1.0 21.0 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.9 21.6 GO:0045475 locomotor rhythm(GO:0045475)
0.9 2.7 GO:0006045 N-acetylglucosamine biosynthetic process(GO:0006045) N-acetylneuraminate biosynthetic process(GO:0046380)
0.8 8.4 GO:0007638 mechanosensory behavior(GO:0007638)
0.8 16.0 GO:0031424 keratinization(GO:0031424)
0.8 10.3 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.7 5.1 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.7 23.4 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.7 82.1 GO:0019882 antigen processing and presentation(GO:0019882)
0.6 7.5 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.6 35.2 GO:0031103 axon regeneration(GO:0031103)
0.6 6.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.6 79.9 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.5 6.5 GO:0006983 ER overload response(GO:0006983)
0.5 1.0 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.5 2.6 GO:2000790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584) regulation of mesenchymal cell proliferation involved in lung development(GO:2000790) negative regulation of mesenchymal cell proliferation involved in lung development(GO:2000791)
0.5 7.9 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.5 2.0 GO:0036438 maintenance of lens transparency(GO:0036438)
0.5 3.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.5 28.0 GO:0007566 embryo implantation(GO:0007566)
0.4 31.5 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.4 7.5 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.4 10.4 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.4 7.5 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.4 1.2 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.4 37.8 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.4 1.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.4 1.8 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.4 9.5 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.3 4.1 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.3 10.9 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.3 72.1 GO:0001763 morphogenesis of a branching structure(GO:0001763)
0.3 3.8 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.3 5.7 GO:0006020 inositol metabolic process(GO:0006020)
0.3 3.1 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.3 3.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.3 12.1 GO:0061512 protein localization to cilium(GO:0061512)
0.3 2.4 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.3 30.0 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.2 2.0 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.2 4.0 GO:0035357 peroxisome proliferator activated receptor signaling pathway(GO:0035357)
0.2 6.0 GO:0007602 phototransduction(GO:0007602)
0.2 2.0 GO:0008063 Toll signaling pathway(GO:0008063)
0.2 19.8 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.2 7.5 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.2 4.4 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.2 2.0 GO:0035634 response to stilbenoid(GO:0035634)
0.1 0.9 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.8 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 5.0 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.1 1.4 GO:0006063 uronic acid metabolic process(GO:0006063) glucuronate metabolic process(GO:0019585) cellular glucuronidation(GO:0052695)
0.1 1.4 GO:2000505 regulation of energy homeostasis(GO:2000505)
0.1 9.1 GO:0007601 visual perception(GO:0007601)
0.1 1.6 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.4 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.1 1.2 GO:0043248 proteasome assembly(GO:0043248)
0.1 98.6 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.1 0.7 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 4.3 GO:0060070 canonical Wnt signaling pathway(GO:0060070)
0.1 1.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 2.4 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.5 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 2.9 GO:0007416 synapse assembly(GO:0007416)
0.0 0.9 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 2.9 GO:0031334 positive regulation of protein complex assembly(GO:0031334)
0.0 4.1 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)
0.0 0.1 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
20.2 60.7 GO:0098830 presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
19.7 79.0 GO:0061474 phagolysosome membrane(GO:0061474)
12.9 77.3 GO:0033269 internode region of axon(GO:0033269)
7.2 72.2 GO:0042788 polysomal ribosome(GO:0042788)
6.2 43.3 GO:0045293 mRNA editing complex(GO:0045293)
5.6 84.2 GO:0032591 dendritic spine membrane(GO:0032591)
5.4 48.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
5.0 40.2 GO:0032584 growth cone membrane(GO:0032584)
4.0 63.9 GO:0005883 neurofilament(GO:0005883)
4.0 23.8 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
3.3 16.5 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
3.1 30.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
2.5 19.7 GO:0044305 calyx of Held(GO:0044305)
2.5 31.9 GO:0005652 nuclear lamina(GO:0005652)
2.2 10.9 GO:0070695 FHF complex(GO:0070695)
2.2 34.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
2.1 6.2 GO:0042642 actomyosin, myosin complex part(GO:0042642)
2.1 57.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
2.0 24.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
1.9 3.8 GO:0097441 basilar dendrite(GO:0097441)
1.9 11.2 GO:0005726 perichromatin fibrils(GO:0005726)
1.8 8.9 GO:0070195 growth hormone receptor complex(GO:0070195)
1.7 50.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
1.6 4.8 GO:0031510 SUMO activating enzyme complex(GO:0031510)
1.5 34.1 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
1.4 19.7 GO:0032426 stereocilium tip(GO:0032426)
1.4 4.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
1.1 83.2 GO:0005581 collagen trimer(GO:0005581)
1.1 150.4 GO:0072562 blood microparticle(GO:0072562)
1.1 14.8 GO:0031258 lamellipodium membrane(GO:0031258)
1.0 5.1 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
1.0 2.0 GO:0043219 lateral loop(GO:0043219)
1.0 5.0 GO:0061689 tricellular tight junction(GO:0061689)
0.7 6.4 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.7 260.3 GO:0030133 transport vesicle(GO:0030133)
0.7 16.0 GO:0030057 desmosome(GO:0030057)
0.6 7.5 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.6 13.2 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.5 16.9 GO:0032420 stereocilium(GO:0032420)
0.5 20.2 GO:0044295 axonal growth cone(GO:0044295)
0.4 18.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.4 36.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.4 30.1 GO:0031526 brush border membrane(GO:0031526)
0.4 93.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.4 3.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.4 22.9 GO:0030175 filopodium(GO:0030175)
0.4 1.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.4 19.8 GO:0031225 anchored component of membrane(GO:0031225)
0.4 67.1 GO:0043209 myelin sheath(GO:0043209)
0.3 77.0 GO:0014069 postsynaptic density(GO:0014069)
0.3 19.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.2 18.3 GO:0030426 growth cone(GO:0030426)
0.2 137.6 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.2 0.7 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.2 11.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 1.3 GO:0034464 BBSome(GO:0034464)
0.1 14.9 GO:0016363 nuclear matrix(GO:0016363)
0.1 6.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 26.9 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.1 31.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 14.8 GO:0005874 microtubule(GO:0005874)
0.1 1.2 GO:0008305 integrin complex(GO:0008305)
0.1 18.1 GO:0030424 axon(GO:0030424)
0.0 17.0 GO:0043005 neuron projection(GO:0043005)
0.0 1.0 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 4.1 GO:0005770 late endosome(GO:0005770)
0.0 40.5 GO:0005739 mitochondrion(GO:0005739)
0.0 1.2 GO:0000502 proteasome complex(GO:0000502)
0.0 1.5 GO:0001650 fibrillar center(GO:0001650)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
21.3 106.3 GO:0005534 galactose binding(GO:0005534)
11.4 34.3 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
10.0 80.4 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
9.5 95.1 GO:0003680 AT DNA binding(GO:0003680)
8.4 25.3 GO:0004556 alpha-amylase activity(GO:0004556)
8.0 39.8 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
7.8 23.3 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
7.6 30.5 GO:0070699 type II activin receptor binding(GO:0070699)
7.6 45.4 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
6.9 90.1 GO:0019841 retinol binding(GO:0019841)
6.7 60.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
6.6 19.7 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
6.4 19.3 GO:0004736 pyruvate carboxylase activity(GO:0004736)
6.4 121.4 GO:0015643 toxic substance binding(GO:0015643)
6.0 59.9 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
5.8 23.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
5.7 22.9 GO:1903135 cupric ion binding(GO:1903135)
5.7 28.5 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
5.7 22.6 GO:0030294 receptor signaling protein tyrosine kinase inhibitor activity(GO:0030294)
5.6 134.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
4.9 14.8 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
4.9 63.9 GO:0098919 structural constituent of postsynaptic specialization(GO:0098879) structural constituent of postsynaptic density(GO:0098919)
4.4 17.5 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
3.8 30.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
3.7 11.2 GO:0042296 ISG15 transferase activity(GO:0042296)
3.4 23.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
3.3 16.5 GO:0050816 phosphothreonine binding(GO:0050816)
3.3 82.1 GO:0031489 myosin V binding(GO:0031489)
3.2 25.9 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
3.2 15.9 GO:0005042 netrin receptor activity(GO:0005042)
3.2 82.3 GO:0017091 AU-rich element binding(GO:0017091)
3.0 42.2 GO:0042043 neurexin family protein binding(GO:0042043)
2.9 35.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
2.9 14.5 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
2.9 20.2 GO:0097109 neuroligin family protein binding(GO:0097109)
2.8 85.1 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
2.7 50.4 GO:0030955 potassium ion binding(GO:0030955)
2.2 8.9 GO:0004903 growth hormone receptor activity(GO:0004903)
2.2 8.9 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
2.2 19.7 GO:0019992 diacylglycerol binding(GO:0019992)
2.1 10.7 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
2.0 40.5 GO:0005003 ephrin receptor activity(GO:0005003)
1.8 5.5 GO:0016414 carnitine O-octanoyltransferase activity(GO:0008458) O-octanoyltransferase activity(GO:0016414)
1.7 17.2 GO:0005132 type I interferon receptor binding(GO:0005132)
1.7 34.9 GO:0002162 dystroglycan binding(GO:0002162)
1.6 4.9 GO:0017168 5-oxoprolinase (ATP-hydrolyzing) activity(GO:0017168)
1.3 9.2 GO:0004064 arylesterase activity(GO:0004064)
1.3 7.9 GO:0048039 ubiquinone binding(GO:0048039)
1.3 11.6 GO:0004385 guanylate kinase activity(GO:0004385)
1.2 4.8 GO:0044388 small protein activating enzyme binding(GO:0044388)
1.2 5.8 GO:0042030 ATPase inhibitor activity(GO:0042030)
1.1 16.3 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
1.1 44.0 GO:0030507 spectrin binding(GO:0030507)
1.0 4.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
1.0 189.7 GO:0051015 actin filament binding(GO:0051015)
1.0 62.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
1.0 3.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.9 22.1 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.9 6.4 GO:0097322 7SK snRNA binding(GO:0097322)
0.9 18.1 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.8 4.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.8 11.5 GO:0051378 serotonin binding(GO:0051378)
0.8 3.3 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.8 6.2 GO:0000146 microfilament motor activity(GO:0000146)
0.8 76.2 GO:0016503 pheromone receptor activity(GO:0016503)
0.7 11.5 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.7 32.8 GO:0070888 E-box binding(GO:0070888)
0.7 36.8 GO:0015459 potassium channel regulator activity(GO:0015459)
0.7 84.2 GO:0044325 ion channel binding(GO:0044325)
0.6 7.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.6 19.2 GO:0050681 androgen receptor binding(GO:0050681)
0.6 3.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.5 3.3 GO:0005047 signal recognition particle binding(GO:0005047)
0.5 3.8 GO:0015172 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.5 6.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.5 1.5 GO:0052723 inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.5 2.0 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.4 34.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.4 2.4 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.3 2.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.3 1.6 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.3 15.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.3 5.7 GO:0008199 ferric iron binding(GO:0008199)
0.3 2.8 GO:0008432 JUN kinase binding(GO:0008432)
0.3 8.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 8.4 GO:0008009 chemokine activity(GO:0008009)
0.2 7.5 GO:0042169 SH2 domain binding(GO:0042169)
0.2 8.8 GO:0019213 deacetylase activity(GO:0019213)
0.2 3.6 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.2 0.5 GO:0019961 interferon binding(GO:0019961)
0.2 0.8 GO:0004969 histamine receptor activity(GO:0004969)
0.1 2.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.4 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 3.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 4.2 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.1 11.4 GO:0047485 protein N-terminus binding(GO:0047485)
0.1 3.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 5.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 16.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 5.1 GO:0001948 glycoprotein binding(GO:0001948)
0.1 5.1 GO:0008013 beta-catenin binding(GO:0008013)
0.1 0.9 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 8.4 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1 22.7 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 22.0 GO:0005549 odorant binding(GO:0005549)
0.1 11.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 4.2 GO:0008565 protein transporter activity(GO:0008565)
0.0 3.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.5 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 121.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
1.5 31.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
1.0 95.1 PID CDC42 PATHWAY CDC42 signaling events
0.9 55.2 PID LKB1 PATHWAY LKB1 signaling events
0.8 18.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.7 110.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.7 11.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.6 11.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.6 16.5 PID MYC PATHWAY C-MYC pathway
0.6 15.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.6 5.9 ST JAK STAT PATHWAY Jak-STAT Pathway
0.5 6.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.5 22.6 PID BMP PATHWAY BMP receptor signaling
0.4 107.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.4 5.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.4 27.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.4 6.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.3 8.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.3 7.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.2 3.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 10.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.2 8.2 PID ARF6 PATHWAY Arf6 signaling events
0.2 6.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 3.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 2.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 4.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.4 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.9 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
15.1 151.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
9.7 106.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
7.3 80.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
6.3 95.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
4.4 105.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
4.2 25.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
2.2 35.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
1.2 34.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
1.2 16.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
1.1 30.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
1.0 42.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.9 19.7 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.9 33.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.9 24.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.8 79.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.8 30.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.8 11.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.8 6.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.7 6.0 REACTOME OPSINS Genes involved in Opsins
0.7 23.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.6 11.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.6 16.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.5 16.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.5 13.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.5 31.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.4 7.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.4 18.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.4 8.9 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.4 10.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.4 18.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.4 6.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.3 9.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.3 17.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.3 6.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.3 5.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.2 4.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 2.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.2 4.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 2.0 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.2 8.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.7 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 16.9 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.1 8.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 2.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 4.0 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 2.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.8 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 4.3 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 1.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions