ISMARA results: Nfil3

Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation

Downloads

Results for Nfil3_Tef

Z-value: 1.93

Motif logo

Transcription factors associated with Nfil3_Tef

Gene Symbol	Gene ID	Gene Info
Nfil3 NCBI RGD Ensembl	ENSRNOG00000011668	nuclear factor, interleukin 3 regulated
Tef NCBI RGD Ensembl	ENSRNOG00000019383	TEF, PAR bZIP transcription factor

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Tef	rn6_v1_chr7_+_123043503_123043584	0.39	5.2e-13	Click!
Nfil3	rn6_v1_chr17_+_12261102_12261102	0.28	3.8e-07	Click!

Activity profile of Nfil3_Tef motif

Sorted Z-values of Nfil3_Tef motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr9_+_73529612 Show fit	164.17	ENSRNOT00000032430	Unc80 NCBI RGD Ensembl Show fit	unc-80 homolog, NALCN activator
chr14_-_19191863 Show fit	121.38	ENSRNOT00000003921	Alb NCBI RGD Ensembl Show fit	albumin
chr17_+_41798783 Show fit	113.30	ENSRNOT00000023519	Nrsn1 NCBI RGD Ensembl Show fit	neurensin 1
chr1_+_248428099 Show fit	106.32	ENSRNOT00000050984	Mbl2 NCBI RGD Ensembl Show fit	mannose binding lectin 2
chr5_+_120340646 Show fit	105.83	ENSRNOT00000086259 ENSRNOT00000086539	Dnajc6 NCBI RGD Ensembl Show fit	DnaJ heat shock protein family (Hsp40) member C6
chr4_-_85915099 Show fit	104.03	ENSRNOT00000016182	Neurod6 NCBI RGD Ensembl Show fit	neuronal differentiation 6
chr3_+_95715193 Show fit	95.12	ENSRNOT00000089525	Pax6 NCBI RGD Ensembl Show fit	paired box 6
chr1_-_256813711 Show fit	90.05	ENSRNOT00000021055	Rbp4 NCBI RGD Ensembl Show fit	retinol binding protein 4
chr5_-_130085838 Show fit	82.25	ENSRNOT00000035252	Elavl4 NCBI RGD Ensembl Show fit	ELAV like RNA binding protein 4
chr2_-_41784929 Show fit	82.11	ENSRNOT00000086851	Rab3c NCBI RGD Ensembl Show fit	RAB3C, member RAS oncogene family

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfil3_Tef

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
20.2	121.4	GO:0044004	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004) response to platinum ion(GO:0070541)
26.6	106.3	GO:2000259	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
26.5	105.8	GO:0072318	clathrin coat disassembly(GO:0072318)
4.5	104.0	GO:0021542	dentate gyrus development(GO:0021542)
1.4	102.0	GO:0042220	response to cocaine(GO:0042220)
0.1	98.6	GO:0007606	sensory perception of chemical stimulus(GO:0007606)
31.7	95.1	GO:0021917	pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
30.0	90.1	GO:0046865	isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
1.3	84.2	GO:0060291	long-term synaptic potentiation(GO:0060291)
0.7	82.1	GO:0019882	antigen processing and presentation(GO:0019882)

Showing 1 to 10 of 140 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	260.3	GO:0030133	transport vesicle(GO:0030133)
1.1	150.4	GO:0072562	blood microparticle(GO:0072562)
0.2	137.6	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.4	93.6	GO:0016323	basolateral plasma membrane(GO:0016323)
5.6	84.2	GO:0032591	dendritic spine membrane(GO:0032591)
1.1	83.2	GO:0005581	collagen trimer(GO:0005581)
19.7	79.0	GO:0061474	phagolysosome membrane(GO:0061474)
12.9	77.3	GO:0033269	internode region of axon(GO:0033269)
0.3	77.0	GO:0014069	postsynaptic density(GO:0014069)
7.2	72.2	GO:0042788	polysomal ribosome(GO:0042788)

Showing 1 to 10 of 69 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	189.7	GO:0051015	actin filament binding(GO:0051015)
5.6	134.9	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
6.4	121.4	GO:0015643	toxic substance binding(GO:0015643)
21.3	106.3	GO:0005534	galactose binding(GO:0005534)
9.5	95.1	GO:0003680	AT DNA binding(GO:0003680)
6.9	90.1	GO:0019841	retinol binding(GO:0019841)
2.8	85.1	GO:0008392	arachidonic acid epoxygenase activity(GO:0008392)
0.7	84.2	GO:0044325	ion channel binding(GO:0044325)
3.2	82.3	GO:0017091	AU-rich element binding(GO:0017091)
3.3	82.1	GO:0031489	myosin V binding(GO:0031489)

Showing 1 to 10 of 112 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
2.2	121.4	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.7	110.4	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.4	107.5	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
1.0	95.1	PID CDC42 PATHWAY	CDC42 signaling events
0.9	55.2	PID LKB1 PATHWAY	LKB1 signaling events
1.5	31.9	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.4	27.9	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.5	22.6	PID BMP PATHWAY	BMP receptor signaling
0.8	18.7	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.6	16.5	PID MYC PATHWAY	C-MYC pathway

Showing 1 to 10 of 31 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
15.1	151.4	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
9.7	106.3	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
4.4	105.8	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
6.3	95.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
7.3	80.4	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.8	79.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
1.0	42.7	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
2.2	35.4	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
1.2	34.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.9	33.5	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis

Showing 1 to 10 of 53 entries

Results for Nfil3_Tef

Z-value: 1.93

Motif logo

Transcription factors associated with Nfil3_Tef

Activity-expression correlation:

Activity profile of Nfil3_Tef motif

Sorted Z-values of Nfil3_Tef motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfil3_Tef

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: