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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Nfic_Nfib

Z-value: 2.06

Motif logo

Transcription factors associated with Nfic_Nfib

Gene Symbol Gene ID Gene Info
ENSRNOG00000004505 nuclear factor I/C
ENSRNOG00000009795 nuclear factor I/B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfibrn6_v1_chr5_-_100647298_1006472980.672.7e-43Click!
Nficrn6_v1_chr7_+_11152038_111520380.631.9e-37Click!

Activity profile of Nfic_Nfib motif

Sorted Z-values of Nfic_Nfib motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_27815261 182.81 ENSRNOT00000032992
kelch-like family member 33
chr5_-_134526089 94.70 ENSRNOT00000013321
cytochrome P450, family 4, subfamily b, polypeptide 1
chr1_-_89543967 81.57 ENSRNOT00000079631
hepsin
chr9_-_82008620 71.34 ENSRNOT00000023365
protein kinase AMP-activated non-catalytic subunit gamma 3
chr16_+_54291251 66.73 ENSRNOT00000079006
microtubule associated tumor suppressor 1
chr10_+_57278307 64.19 ENSRNOT00000005612
enolase 3
chr5_-_101166651 62.48 ENSRNOT00000078862
Fras1 related extracellular matrix 1
chr1_-_100530183 61.21 ENSRNOT00000067754
myosin binding protein C, fast-type
chr9_-_80167033 60.48 ENSRNOT00000023530
insulin-like growth factor binding protein 5
chr9_-_20195566 59.96 ENSRNOT00000015223
adhesion G protein-coupled receptor F5
chr8_-_130429132 59.67 ENSRNOT00000026261
hedgehog acyltransferase-like
chr19_-_56677084 58.49 ENSRNOT00000024084
actin, alpha 1, skeletal muscle
chr9_-_80166807 57.48 ENSRNOT00000079493
insulin-like growth factor binding protein 5
chr4_-_85386231 55.73 ENSRNOT00000015316
indolethylamine N-methyltransferase
chr3_+_11679530 54.30 ENSRNOT00000074562
ENSRNOT00000071801
endoglin
chr5_+_159967839 53.61 ENSRNOT00000051317
heat shock protein family B (small) member 7
chr20_+_5008508 52.49 ENSRNOT00000001153
von Willebrand factor A domain containing 7
chr6_-_129010271 52.06 ENSRNOT00000075378
serpin family A member 10
chrX_-_134866210 50.54 ENSRNOT00000005331
apelin
chr7_-_144993652 50.52 ENSRNOT00000087748
integrin subunit alpha 5
chr7_-_15190796 49.40 ENSRNOT00000006533
cytochrome P450, family 4, subfamily f, polypeptide 1
chr4_+_44597123 47.15 ENSRNOT00000078250
caveolin 1
chr1_-_198104109 46.31 ENSRNOT00000026186
sulfotransferase family 1A member 1
chr3_+_14467330 46.03 ENSRNOT00000078939
gelsolin
chr4_+_56711049 45.73 ENSRNOT00000027237
filamin C
chr5_+_134492756 42.28 ENSRNOT00000012888
ENSRNOT00000057095
ENSRNOT00000051385
cytochrome P450, family 4, subfamily a, polypeptide 1
chr1_+_48273611 41.77 ENSRNOT00000022254
ENSRNOT00000022068
solute carrier family 22 member 1
chr8_+_59507990 41.72 ENSRNOT00000018003
hydroxylysine kinase
chr1_+_80321585 40.43 ENSRNOT00000022895
creatine kinase, M-type
chr12_+_24978483 40.03 ENSRNOT00000040069
elastin
chr10_+_49231730 38.77 ENSRNOT00000065335
tripartite motif-containing 16
chr13_-_84331905 38.45 ENSRNOT00000004965
dual specificity phosphatase 27 (putative)
chr8_-_55177818 38.18 ENSRNOT00000013960
heat shock protein family B (small) member 2
chr5_-_93244202 37.62 ENSRNOT00000075474
protein tyrosine phosphatase, receptor type, D
chr1_-_49844547 36.79 ENSRNOT00000086127
ENSRNOT00000077423
ENSRNOT00000089439
ENSRNOT00000090521

chr16_-_74122889 35.38 ENSRNOT00000025763
plasminogen activator, tissue type
chr5_-_75005567 35.05 ENSRNOT00000016068
hypothetical protein LOC685849
chr19_+_23389375 33.15 ENSRNOT00000018629
spalt-like transcription factor 1
chr4_+_169147243 32.57 ENSRNOT00000011580
epithelial membrane protein 1
chr20_+_6923489 32.49 ENSRNOT00000093373
ENSRNOT00000000632
peptidase inhibitor 16
chr13_-_80738634 32.47 ENSRNOT00000081551
flavin containing monooxygenase 1
chr8_-_58195884 32.38 ENSRNOT00000010573
acetyl-CoA acetyltransferase 1
chr9_+_46996156 32.21 ENSRNOT00000019673
interleukin 1 receptor type 1
chr4_+_144382945 32.17 ENSRNOT00000007601
caveolin 3
chr6_+_107245820 32.16 ENSRNOT00000012757
papilin, proteoglycan-like sulfated glycoprotein
chr4_-_100232559 32.01 ENSRNOT00000016984
vesicle-associated membrane protein 5
chr1_-_213650247 31.34 ENSRNOT00000019679
cytochrome c oxidase, subunit VIIIb
chr9_+_50526811 30.74 ENSRNOT00000036990
similar to RIKEN cDNA 1500015O10
chr4_+_169161585 30.63 ENSRNOT00000079785
epithelial membrane protein 1
chr9_+_46997798 30.59 ENSRNOT00000087112
ENSRNOT00000082408
interleukin 1 receptor type 1
chr4_+_62220736 30.03 ENSRNOT00000086377
caldesmon 1
chr3_-_110556808 29.95 ENSRNOT00000092158
ENSRNOT00000045362
similar to hypothetical protein
chr11_-_39448503 29.78 ENSRNOT00000047347
SH3 domain-binding glutamic acid-rich protein-like
chr14_-_8510138 29.21 ENSRNOT00000080758
Rho GTPase activating protein 24
chr18_+_30954609 29.08 ENSRNOT00000086893
protocadherin gamma subfamily C, 3
chr7_-_119441487 28.73 ENSRNOT00000067635
parvalbumin
chr15_+_33632416 28.72 ENSRNOT00000068212

chr10_-_62254287 28.68 ENSRNOT00000004313
serpin family F member 1
chr16_+_54153054 28.50 ENSRNOT00000090644
ENSRNOT00000014248
fibrinogen-like 1
chr2_+_68820615 27.96 ENSRNOT00000087007
ENSRNOT00000089504
epidermal growth factor
chr16_-_8885797 27.90 ENSRNOT00000073370
similar to chromosome 10 open reading frame 71
chr3_+_109862117 27.88 ENSRNOT00000083351
ENSRNOT00000070912
thrombospondin 1
chr3_-_10371240 27.31 ENSRNOT00000012075
argininosuccinate synthase 1
chr2_+_84645084 26.95 ENSRNOT00000015448
carboxymethylenebutenolidase homolog
chr10_-_94557764 26.83 ENSRNOT00000016841
sodium voltage-gated channel alpha subunit 4
chr2_+_95320283 26.68 ENSRNOT00000015537
hes-related family bHLH transcription factor with YRPW motif 1
chr2_+_235264219 26.66 ENSRNOT00000086245
complement factor I
chr7_+_116632506 26.38 ENSRNOT00000009811
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
chr2_-_235177275 26.16 ENSRNOT00000093153
uncharacterized LOC103691699
chr2_-_236395067 25.97 ENSRNOT00000014658
hydroxyacyl-CoA dehydrogenase
chr10_+_56662242 25.36 ENSRNOT00000086919
asialoglycoprotein receptor 1
chr3_-_175601127 25.27 ENSRNOT00000081226
laminin subunit alpha 5
chr3_-_160853650 25.07 ENSRNOT00000018844
matrilin 4
chr2_+_61039053 25.03 ENSRNOT00000025693
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr3_+_171213936 24.96 ENSRNOT00000031586
phosphoenolpyruvate carboxykinase 1
chr5_+_164808323 24.55 ENSRNOT00000011005
natriuretic peptide A
chr1_+_83653234 24.29 ENSRNOT00000085008
ENSRNOT00000084230
ENSRNOT00000090071
cytochrome P450, family 2, subfamily a, polypeptide 1
chr13_+_112031594 23.99 ENSRNOT00000008440
laminin subunit beta 3
chr7_+_94375020 23.70 ENSRNOT00000011904
nephroblastoma overexpressed
chr4_-_147163467 23.53 ENSRNOT00000010748
tissue inhibitor of metalloproteinase 4
chr8_+_85355766 22.78 ENSRNOT00000010583
glial cells missing homolog 1
chr1_-_167202767 22.69 ENSRNOT00000055243
ADP-ribosyltransferase 5
chr1_+_219764001 22.35 ENSRNOT00000082388
pyruvate carboxylase
chr5_+_148257642 21.79 ENSRNOT00000067663
collagen type XVI alpha 1 chain
chr1_-_241155537 21.55 ENSRNOT00000034216
ENSRNOT00000073493
MAM domain containing 2
chr3_-_8979889 21.15 ENSRNOT00000065128
carnitine O-acetyltransferase
chr4_+_44573264 21.12 ENSRNOT00000080271
caveolin 2
chr1_-_221281180 20.53 ENSRNOT00000028379
CDC42 effector protein 2
chr6_+_119519714 20.37 ENSRNOT00000004955
fibronectin leucine rich transmembrane protein 2
chr9_-_9985630 20.18 ENSRNOT00000071780
crumbs 3, cell polarity complex component
chr10_-_98390384 20.09 ENSRNOT00000065947
ATP-binding cassette, subfamily A (ABC1), member 8a
chr13_+_47454591 20.00 ENSRNOT00000005791
similar to specifically androgen-regulated protein
chr15_-_52210746 19.72 ENSRNOT00000046054
bone morphogenetic protein 1
chr1_+_89008117 19.48 ENSRNOT00000028401
heat shock protein family B (small) member 6
chr5_-_61077627 19.22 ENSRNOT00000015338
SH2 domain containing adaptor protein B
chr7_+_139698148 18.98 ENSRNOT00000078579
phosphofructokinase, muscle
chr7_-_15225309 18.84 ENSRNOT00000075589
ENSRNOT00000066095
cytochrome P450, family 4, subfamily f, polypeptide 6
chr2_-_47281421 18.37 ENSRNOT00000086114
integrin subunit alpha 1
chr9_+_94702129 18.17 ENSRNOT00000080930
neuraminidase 2
chr1_-_261986759 18.17 ENSRNOT00000021257
pyridine nucleotide-disulphide oxidoreductase domain 2
chr18_+_32273770 18.15 ENSRNOT00000087408
fibroblast growth factor 1
chr9_+_46962288 18.14 ENSRNOT00000082146
interleukin 1 receptor type 1
chr1_+_101012822 17.76 ENSRNOT00000027809
related RAS viral (r-ras) oncogene homolog
chr4_-_115332052 17.73 ENSRNOT00000017643
C-type lectin domain family 4, member F
chr16_+_59077574 17.58 ENSRNOT00000090477
DLC1 Rho GTPase activating protein
chr8_-_22821223 17.44 ENSRNOT00000014135
KN motif and ankyrin repeat domains 2
chr1_+_144239020 16.91 ENSRNOT00000032106
ADAMTS-like 3
chr16_+_49266903 16.64 ENSRNOT00000014704
solute carrier family 25 member 4
chr14_+_80403001 16.38 ENSRNOT00000012109
carboxypeptidase Z
chr13_+_89524329 16.18 ENSRNOT00000004279
myelin protein zero
chr4_+_7158448 16.14 ENSRNOT00000076953
ankyrin repeat and SOCS box-containing 10
chr3_+_63510293 16.06 ENSRNOT00000058093
deafness, autosomal recessive 59
chr16_-_40025401 15.91 ENSRNOT00000066639
ankyrin repeat and SOCS box-containing 5
chr8_+_95968652 15.68 ENSRNOT00000015057
5' nucleotidase, ecto
chr5_+_140888973 15.66 ENSRNOT00000020524
5'-nucleotidase, cytosolic IA
chr1_-_215033460 15.65 ENSRNOT00000044565
dual specificity phosphatase 8
chr9_-_100306194 15.51 ENSRNOT00000087584
similar to hypothetical protein FLJ22671
chr10_-_88036040 15.49 ENSRNOT00000018851
keratin 13
chr10_-_104659188 15.22 ENSRNOT00000010887
tripartite motif-containing 47
chr7_-_139907640 15.21 ENSRNOT00000045473
zinc finger protein 641
chr1_-_170318935 15.19 ENSRNOT00000024119
protein kinase C, delta binding protein
chr7_-_31824064 15.15 ENSRNOT00000011494
ENSRNOT00000080824
solute carrier family 25 member 3
chr10_+_86950557 15.10 ENSRNOT00000014153
insulin-like growth factor binding protein 4
chr12_-_51250230 15.05 ENSRNOT00000029508
meningioma 1
chr8_-_22821397 15.01 ENSRNOT00000045488
KN motif and ankyrin repeat domains 2
chr9_+_16924520 14.86 ENSRNOT00000025094
solute carrier family 22 member 7
chr4_+_62019970 14.85 ENSRNOT00000013133
aldose reductase-related protein 1-like
chr1_-_222350173 14.77 ENSRNOT00000030625
fibronectin leucine rich transmembrane protein 1
chr17_+_80882666 14.73 ENSRNOT00000024430
vimentin
chr12_-_46809849 14.55 ENSRNOT00000081134
paxillin
chr1_-_175796040 14.45 ENSRNOT00000024060
murine retrovirus integration site 1 homolog
chr6_-_109935533 14.43 ENSRNOT00000013516
transforming growth factor, beta 3
chr3_+_112428395 14.42 ENSRNOT00000079109
ENSRNOT00000048141
StAR-related lipid transfer domain containing 9
chr2_-_147392062 14.36 ENSRNOT00000021535
transmembrane 4 L six family member 1
chr9_+_82596355 14.34 ENSRNOT00000065076
SPEG complex locus
chr2_-_195888216 14.33 ENSRNOT00000056436
tuftelin 1
chrX_+_68771100 14.06 ENSRNOT00000043872
StAR-related lipid transfer domain containing 8
chr3_+_160207913 13.93 ENSRNOT00000014346
WNT1 inducible signaling pathway protein 2
chr8_-_62458301 13.92 ENSRNOT00000021653
cytochrome P450, family 1, subfamily a, polypeptide 2
chr1_-_126211439 13.65 ENSRNOT00000014988
tight junction protein 1
chr5_-_171710312 13.38 ENSRNOT00000076044
ENSRNOT00000071280
ENSRNOT00000072059
ENSRNOT00000077015
PR/SET domain 16
chr18_+_32336102 13.38 ENSRNOT00000018577
fibroblast growth factor 1
chr11_-_69223158 13.20 ENSRNOT00000067060
myosin light chain kinase
chr1_+_198199622 13.14 ENSRNOT00000026688
glycerophosphodiester phosphodiesterase domain containing 3
chr19_+_61332351 13.11 ENSRNOT00000014492
neuropilin 1
chr1_+_91433030 13.08 ENSRNOT00000015205
solute carrier family 7 member 10
chr1_+_221099998 13.04 ENSRNOT00000028262
latent transforming growth factor beta binding protein 3
chr6_-_62798384 12.88 ENSRNOT00000093200
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10-like 1
chr8_-_115140080 12.83 ENSRNOT00000015851
aminoacylase 1
chr1_+_148240504 12.78 ENSRNOT00000085373
Cytochrome P450, family 2, subfamily c, polypeptide 7-like
chr13_-_52088780 12.74 ENSRNOT00000008754
E74-like factor 3
chr5_-_4975436 12.47 ENSRNOT00000062006
XK related 9
chr6_-_127534247 12.32 ENSRNOT00000012500
serpin family A member 6
chr10_-_104575890 12.28 ENSRNOT00000050223
H3 histone family member 3B
chr9_-_55256340 12.13 ENSRNOT00000028907
serum deprivation response
chr4_-_145300177 12.12 ENSRNOT00000029728
calcium/calmodulin-dependent protein kinase I
chr4_+_145427367 12.04 ENSRNOT00000037788
interleukin 17 receptor C
chr7_+_142776580 11.62 ENSRNOT00000081047
activin A receptor like type 1
chr13_+_26970896 11.59 ENSRNOT00000003501
serpin family B member 12
chr17_+_72209373 11.58 ENSRNOT00000064802
ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
chr8_+_130401470 11.55 ENSRNOT00000043346
zinc finger and BTB domain containing 47
chr1_-_222177421 11.49 ENSRNOT00000078393
estrogen related receptor, alpha
chr1_-_194769524 11.36 ENSRNOT00000025988
nuclear protein 1, transcriptional regulator
chr1_+_171797516 11.34 ENSRNOT00000088110
PPFIA binding protein 2
chr1_+_214778496 11.10 ENSRNOT00000028967
mucin 5B, oligomeric mucus/gel-forming
chr7_-_117151256 11.00 ENSRNOT00000078846
nuclear receptor binding protein 2
chr9_+_51302151 10.94 ENSRNOT00000085908
GULP, engulfment adaptor PTB domain containing 1
chr13_-_90832469 10.87 ENSRNOT00000086508
immunoglobulin superfamily, member 9
chr5_+_113725717 10.76 ENSRNOT00000032248
TEK receptor tyrosine kinase
chr1_-_188713270 10.71 ENSRNOT00000082192
ENSRNOT00000065892
G protein-coupled receptor, class C, group 5, member B
chr7_-_117151694 10.71 ENSRNOT00000051294
nuclear receptor binding protein 2
chr8_-_21995806 10.60 ENSRNOT00000028034
sphingosine-1-phosphate receptor 2
chr2_+_233615739 10.51 ENSRNOT00000051009
paired-like homeodomain 2
chr11_+_30363280 10.48 ENSRNOT00000002885
superoxide dismutase 1, soluble
chr7_-_117679219 10.47 ENSRNOT00000071522
solute carrier family 39 member 4
chr1_-_162385575 10.45 ENSRNOT00000016540
thyroid hormone responsive
chr1_-_12952906 10.45 ENSRNOT00000078193
hypothetical protein LOC100360362
chr3_+_98297554 10.41 ENSRNOT00000006524
potassium voltage-gated channel subfamily A member 4
chr5_+_76812931 10.40 ENSRNOT00000059458
hydroxysteroid dehydrogenase like 2
chr5_-_33182147 10.31 ENSRNOT00000080358
MAGE family member D2
chr13_+_26970660 10.30 ENSRNOT00000083145
serpin family B member 12
chr2_+_143951838 10.22 ENSRNOT00000079544
mothers against decapentaplegic homolog 9
chr13_-_80775230 10.21 ENSRNOT00000091389
ENSRNOT00000004762
flavin containing monooxygenase 2
chr5_-_126096068 10.19 ENSRNOT00000036793

chr2_+_251863069 10.18 ENSRNOT00000036282
synapse defective Rho GTPase homolog 2
chrX_+_143097525 10.09 ENSRNOT00000004559
coagulation factor IX
chr7_-_143420027 9.89 ENSRNOT00000082863
keratin 2
chr3_+_5624506 9.76 ENSRNOT00000036995
ADAMTS-like 2
chr8_-_105462141 9.69 ENSRNOT00000066731
ENSRNOT00000078760
calsyntenin 2
chr7_+_2752680 9.62 ENSRNOT00000033726
citrate synthase
chr5_+_58144705 9.61 ENSRNOT00000019886
galactose-1-phosphate uridylyltransferase
chr15_-_46367302 9.61 ENSRNOT00000032089
farnesyl diphosphate farnesyl transferase 1
chr16_-_7408265 9.51 ENSRNOT00000035009
dynein, axonemal, heavy chain 1
chr3_-_8766433 9.39 ENSRNOT00000021865
kynurenine aminotransferase 1
chr3_-_48535909 9.34 ENSRNOT00000008148
fibroblast activation protein, alpha
chr4_-_60358562 9.31 ENSRNOT00000018001
coiled-coil-helix-coiled-coil-helix domain containing 3
chr13_-_68360664 9.29 ENSRNOT00000030971
hemicentin 1
chr3_-_161067358 9.29 ENSRNOT00000055160
WAP four-disulfide core domain 8
chr11_+_31002451 9.29 ENSRNOT00000002838
eva-1 homolog C
chr9_+_81615251 9.25 ENSRNOT00000081106
ENSRNOT00000020049
paroxysmal nonkinesigenic dyskinesia

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfic_Nfib

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
29.5 118.0 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
27.2 81.6 GO:0034769 basement membrane disassembly(GO:0034769)
27.0 80.9 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
22.8 68.3 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
18.1 54.3 GO:1905072 cardiac jelly development(GO:1905072)
15.3 46.0 GO:1903921 protein processing in phagocytic vesicle(GO:1900756) regulation of establishment of T cell polarity(GO:1903903) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
14.6 58.5 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
13.3 40.0 GO:0071298 cellular response to L-ascorbic acid(GO:0071298)
13.0 13.0 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
12.9 90.0 GO:0018879 biphenyl metabolic process(GO:0018879)
12.6 50.5 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
11.3 56.6 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
11.3 33.9 GO:0006114 glycerol biosynthetic process(GO:0006114)
11.0 33.1 GO:2000384 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
10.8 32.4 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
10.8 32.4 GO:0046356 acetyl-CoA catabolic process(GO:0046356) ketone body catabolic process(GO:0046952) metanephric proximal tubule development(GO:0072237)
10.7 32.2 GO:0035995 detection of muscle stretch(GO:0035995)
10.6 42.3 GO:0048252 lauric acid metabolic process(GO:0048252)
9.9 59.7 GO:1903059 regulation of protein lipidation(GO:1903059)
9.8 88.2 GO:0071073 positive regulation of phospholipid biosynthetic process(GO:0071073)
9.5 38.2 GO:0007525 somatic muscle development(GO:0007525)
9.3 27.9 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of cGMP-mediated signaling(GO:0010752)
9.1 27.3 GO:0000053 argininosuccinate metabolic process(GO:0000053)
8.9 26.7 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
8.8 35.4 GO:0060279 positive regulation of ovulation(GO:0060279)
8.8 26.4 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
8.2 24.5 GO:1902304 positive regulation of potassium ion export(GO:1902304)
7.9 23.7 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392) negative regulation of sensory perception of pain(GO:1904057)
7.1 28.6 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
6.8 61.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
6.6 46.3 GO:0009812 flavonoid metabolic process(GO:0009812)
6.6 19.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
6.5 38.8 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
5.8 17.4 GO:0097325 melanocyte proliferation(GO:0097325)
5.4 32.5 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
5.3 21.1 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
5.2 15.7 GO:0046086 adenosine biosynthetic process(GO:0046086)
4.8 14.4 GO:1905071 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
4.6 22.8 GO:0060018 astrocyte fate commitment(GO:0060018)
4.5 18.2 GO:0051692 cellular oligosaccharide catabolic process(GO:0051692)
4.4 13.1 GO:0038189 vestibulocochlear nerve structural organization(GO:0021649) neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) renal artery morphogenesis(GO:0061441) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835)
4.3 42.7 GO:0070995 NADPH oxidation(GO:0070995)
4.2 41.8 GO:0015697 quaternary ammonium group transport(GO:0015697)
4.2 16.6 GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity(GO:2000277)
4.0 24.3 GO:0009804 coumarin metabolic process(GO:0009804)
4.0 28.0 GO:0007262 STAT protein import into nucleus(GO:0007262)
4.0 55.6 GO:0032060 bleb assembly(GO:0032060)
3.8 19.2 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
3.8 26.8 GO:0015871 choline transport(GO:0015871)
3.7 14.7 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
3.6 10.8 GO:0048014 Tie signaling pathway(GO:0048014)
3.5 10.5 GO:0021539 subthalamus development(GO:0021539) deltoid tuberosity development(GO:0035993) pulmonary vein morphogenesis(GO:0060577)
3.5 10.5 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
3.5 13.9 GO:0016098 monoterpenoid metabolic process(GO:0016098)
3.4 23.8 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
3.4 20.4 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
3.3 62.5 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
3.3 91.3 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313)
3.2 9.6 GO:0016128 phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
3.2 28.7 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) cellular response to cobalt ion(GO:0071279)
3.2 31.8 GO:0097105 presynaptic membrane assembly(GO:0097105)
3.1 30.7 GO:0070314 G1 to G0 transition(GO:0070314)
2.8 8.3 GO:1904178 sterol regulatory element binding protein import into nucleus(GO:0035105) negative regulation of adipose tissue development(GO:1904178)
2.7 21.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
2.6 31.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
2.5 15.1 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
2.5 7.4 GO:0006214 thymidine catabolic process(GO:0006214) pyrimidine deoxyribonucleoside catabolic process(GO:0046127)
2.5 12.3 GO:0060623 pericentric heterochromatin assembly(GO:0031508) regulation of chromosome condensation(GO:0060623)
2.2 17.8 GO:0046085 adenosine metabolic process(GO:0046085)
2.1 10.5 GO:0097332 response to antipsychotic drug(GO:0097332)
2.1 43.4 GO:0035634 response to stilbenoid(GO:0035634)
2.0 8.2 GO:0045658 regulation of neutrophil differentiation(GO:0045658)
2.0 12.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
2.0 7.9 GO:0060155 platelet dense granule organization(GO:0060155)
1.9 13.4 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
1.9 13.4 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
1.9 9.4 GO:0097052 L-kynurenine metabolic process(GO:0097052)
1.9 5.6 GO:0090648 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) response to methyl methanesulfonate(GO:0072702) cellular response to methyl methanesulfonate(GO:0072703) response to environmental enrichment(GO:0090648) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
1.9 13.1 GO:0042940 D-amino acid transport(GO:0042940)
1.8 9.2 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
1.8 47.3 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
1.8 7.1 GO:0006565 L-serine catabolic process(GO:0006565)
1.8 10.6 GO:1903142 negative regulation of excitatory postsynaptic potential(GO:0090394) positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
1.8 17.6 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
1.7 67.8 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
1.7 6.9 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
1.7 20.5 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
1.7 13.7 GO:0071000 response to magnetism(GO:0071000)
1.7 23.5 GO:0045217 cell-cell junction maintenance(GO:0045217)
1.7 8.4 GO:0060282 negative regulation of cardiac muscle contraction(GO:0055118) positive regulation of oocyte development(GO:0060282)
1.7 6.6 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
1.6 8.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
1.6 44.1 GO:0060046 regulation of acrosome reaction(GO:0060046)
1.6 4.7 GO:0006116 NADH oxidation(GO:0006116)
1.5 15.5 GO:0043587 tongue morphogenesis(GO:0043587)
1.5 10.7 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
1.5 15.1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
1.5 4.5 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
1.4 14.4 GO:0019934 cGMP-mediated signaling(GO:0019934)
1.4 4.3 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
1.4 8.6 GO:0061484 hematopoietic stem cell migration(GO:0035701) hematopoietic stem cell homeostasis(GO:0061484)
1.4 71.3 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
1.4 9.8 GO:0060481 lobar bronchus epithelium development(GO:0060481)
1.4 9.6 GO:0006107 oxaloacetate metabolic process(GO:0006107)
1.3 3.9 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
1.3 10.3 GO:0070294 renal sodium ion absorption(GO:0070294)
1.2 3.7 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
1.2 3.7 GO:0097187 dentinogenesis(GO:0097187)
1.2 37.7 GO:0006958 complement activation, classical pathway(GO:0006958)
1.2 4.8 GO:0097069 cellular response to thyroxine stimulus(GO:0097069)
1.2 3.6 GO:0030824 negative regulation of cGMP metabolic process(GO:0030824)
1.2 7.0 GO:1902617 response to fluoride(GO:1902617)
1.1 28.1 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
1.1 2.2 GO:0007172 signal complex assembly(GO:0007172)
1.0 30.1 GO:0016242 negative regulation of macroautophagy(GO:0016242)
1.0 12.0 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
1.0 9.0 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
1.0 25.3 GO:0001755 neural crest cell migration(GO:0001755)
1.0 14.5 GO:0060396 growth hormone receptor signaling pathway(GO:0060396)
1.0 47.8 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.9 8.1 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.9 10.8 GO:0060056 mammary gland involution(GO:0060056)
0.9 9.9 GO:0051546 keratinocyte migration(GO:0051546)
0.9 11.4 GO:2000194 regulation of female gonad development(GO:2000194)
0.9 7.8 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.9 4.3 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.8 14.4 GO:1902358 oxalate transport(GO:0019532) sulfate transmembrane transport(GO:1902358)
0.8 45.7 GO:0048747 muscle fiber development(GO:0048747)
0.8 3.4 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.8 22.7 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.8 16.2 GO:0006691 leukotriene metabolic process(GO:0006691)
0.8 20.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.8 5.5 GO:0050746 regulation of lipoprotein metabolic process(GO:0050746)
0.8 1.6 GO:0060729 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162) intestinal epithelial structure maintenance(GO:0060729)
0.8 17.1 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.8 7.7 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.8 8.5 GO:0048505 regulation of timing of cell differentiation(GO:0048505)
0.8 5.4 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.7 34.7 GO:0042398 cellular modified amino acid biosynthetic process(GO:0042398)
0.7 19.7 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.7 2.9 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.7 9.3 GO:0042407 cristae formation(GO:0042407)
0.7 35.3 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.7 24.0 GO:0050873 brown fat cell differentiation(GO:0050873)
0.7 2.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.7 15.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.6 23.4 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.6 5.0 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.6 12.3 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.6 2.4 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.6 8.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.6 5.3 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.6 12.0 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.5 1.6 GO:0044565 dendritic cell proliferation(GO:0044565)
0.5 3.6 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.5 6.1 GO:0032534 regulation of microvillus assembly(GO:0032534) intestinal epithelial cell development(GO:0060576)
0.5 1.0 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.5 5.0 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.5 2.0 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.5 17.3 GO:0060612 adipose tissue development(GO:0060612)
0.5 5.5 GO:0046889 positive regulation of lipid biosynthetic process(GO:0046889)
0.5 12.3 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.4 1.8 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.4 1.8 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.4 2.6 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992) response to anoxia(GO:0034059)
0.4 26.0 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.4 11.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.4 9.5 GO:0003351 epithelial cilium movement(GO:0003351)
0.4 6.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.4 4.1 GO:0051132 NK T cell activation(GO:0051132)
0.4 1.9 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.4 11.5 GO:0043030 regulation of macrophage activation(GO:0043030)
0.4 10.9 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.4 3.5 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.3 39.5 GO:0009308 amine metabolic process(GO:0009308)
0.3 4.3 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.3 10.8 GO:0016126 sterol biosynthetic process(GO:0016126)
0.3 13.5 GO:0055013 cardiac muscle cell development(GO:0055013)
0.3 25.2 GO:0009408 response to heat(GO:0009408)
0.3 3.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.3 1.5 GO:1903431 positive regulation of neuron maturation(GO:0014042) positive regulation of cell maturation(GO:1903431)
0.3 4.3 GO:0070166 enamel mineralization(GO:0070166)
0.3 1.1 GO:0015811 L-cystine transport(GO:0015811)
0.3 2.7 GO:1901538 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.3 1.8 GO:0051182 coenzyme transport(GO:0051182)
0.3 4.1 GO:0019236 response to pheromone(GO:0019236)
0.3 40.3 GO:0071559 response to transforming growth factor beta(GO:0071559)
0.2 17.5 GO:0048678 response to axon injury(GO:0048678)
0.2 3.7 GO:0007340 acrosome reaction(GO:0007340)
0.2 9.1 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.2 1.8 GO:0002329 pre-B cell differentiation(GO:0002329)
0.2 7.6 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.2 0.9 GO:0035754 B cell chemotaxis(GO:0035754)
0.2 0.4 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.2 4.9 GO:0097352 autophagosome maturation(GO:0097352)
0.2 1.8 GO:0007000 nucleolus organization(GO:0007000)
0.2 8.2 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.2 2.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 3.5 GO:0006956 complement activation(GO:0006956)
0.2 7.5 GO:0060711 labyrinthine layer development(GO:0060711)
0.2 6.0 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.2 2.9 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.2 1.9 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.1 6.1 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.1 3.4 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)
0.1 3.7 GO:0006458 'de novo' protein folding(GO:0006458)
0.1 20.2 GO:0031668 cellular response to extracellular stimulus(GO:0031668)
0.1 18.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.8 GO:0001835 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 1.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 0.9 GO:0050957 equilibrioception(GO:0050957)
0.1 0.4 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 5.1 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 3.3 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.1 1.3 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 2.4 GO:0005977 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.1 1.8 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095) G2 DNA damage checkpoint(GO:0031572)
0.1 4.4 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 1.9 GO:0009409 response to cold(GO:0009409)
0.1 6.9 GO:0007586 digestion(GO:0007586)
0.1 1.4 GO:0050819 negative regulation of coagulation(GO:0050819)
0.1 25.7 GO:0016311 dephosphorylation(GO:0016311)
0.1 0.2 GO:0071348 response to interleukin-11(GO:0071105) cellular response to interleukin-11(GO:0071348)
0.1 0.3 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.1 5.1 GO:0031638 zymogen activation(GO:0031638)
0.0 1.0 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 8.0 GO:0050808 synapse organization(GO:0050808)
0.0 0.3 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 2.8 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 6.8 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.2 GO:1903894 regulation of IRE1-mediated unfolded protein response(GO:1903894)
0.0 3.2 GO:0015992 proton transport(GO:0015992)
0.0 0.6 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 30.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.6 GO:0044380 protein localization to cytoskeleton(GO:0044380)
0.0 0.1 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.0 GO:0001842 neural fold formation(GO:0001842)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
19.7 118.0 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
12.7 76.1 GO:0030478 actin cap(GO:0030478)
10.7 64.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
8.0 40.0 GO:0071953 elastic fiber(GO:0071953)
6.3 19.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
6.3 25.3 GO:0043259 laminin-10 complex(GO:0043259)
5.2 47.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
5.1 61.2 GO:0005859 muscle myosin complex(GO:0005859)
4.0 27.9 GO:0005577 fibrinogen complex(GO:0005577)
4.0 71.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
3.6 28.7 GO:0043203 axon hillock(GO:0043203)
3.0 24.0 GO:0005610 laminin-5 complex(GO:0005610)
3.0 8.9 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
2.9 14.7 GO:0045098 type III intermediate filament(GO:0045098)
2.5 17.4 GO:0071438 invadopodium membrane(GO:0071438)
2.4 9.5 GO:0036156 inner dynein arm(GO:0036156)
2.4 77.8 GO:0008305 integrin complex(GO:0008305)
2.3 6.9 GO:1990032 parallel fiber(GO:1990032)
2.2 6.6 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
2.1 53.0 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
2.0 31.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
1.8 27.3 GO:0070852 cell body fiber(GO:0070852)
1.7 32.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
1.7 5.0 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
1.6 13.1 GO:0097443 sorting endosome(GO:0097443)
1.5 12.3 GO:0001740 Barr body(GO:0001740)
1.5 6.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
1.5 33.1 GO:0010369 chromocenter(GO:0010369)
1.5 26.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
1.4 11.6 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
1.3 64.5 GO:0016235 aggresome(GO:0016235)
1.3 9.3 GO:0061617 MICOS complex(GO:0061617)
1.2 45.7 GO:0043034 costamere(GO:0043034)
1.2 21.5 GO:0005614 interstitial matrix(GO:0005614)
1.1 13.7 GO:0046581 intercellular canaliculus(GO:0046581)
1.1 3.4 GO:0008537 proteasome activator complex(GO:0008537)
1.1 101.7 GO:0005604 basement membrane(GO:0005604)
1.0 8.3 GO:0005638 lamin filament(GO:0005638)
0.8 7.9 GO:0031083 BLOC-1 complex(GO:0031083)
0.8 21.1 GO:0002080 acrosomal membrane(GO:0002080)
0.7 7.3 GO:0005915 zonula adherens(GO:0005915)
0.7 2.9 GO:0000322 storage vacuole(GO:0000322)
0.7 52.9 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.7 159.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.6 9.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.6 6.0 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.6 8.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.6 32.0 GO:0031201 SNARE complex(GO:0031201)
0.5 13.1 GO:0097440 apical dendrite(GO:0097440)
0.4 31.7 GO:0045095 keratin filament(GO:0045095)
0.4 78.7 GO:0031012 extracellular matrix(GO:0031012)
0.4 46.6 GO:0072562 blood microparticle(GO:0072562)
0.4 10.1 GO:0042629 mast cell granule(GO:0042629)
0.4 3.5 GO:0032437 spectrin(GO:0008091) cuticular plate(GO:0032437)
0.4 14.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.4 118.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.4 272.6 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.3 7.8 GO:0000145 exocyst(GO:0000145)
0.3 4.6 GO:0031528 microvillus membrane(GO:0031528)
0.3 3.7 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.3 1.8 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.3 1.8 GO:0031595 nuclear proteasome complex(GO:0031595)
0.3 319.6 GO:0005615 extracellular space(GO:0005615)
0.3 10.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.3 15.7 GO:0031225 anchored component of membrane(GO:0031225)
0.3 11.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.2 25.3 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.2 1.3 GO:0070449 elongin complex(GO:0070449)
0.2 8.2 GO:0016459 myosin complex(GO:0016459)
0.2 17.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.2 1.6 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.2 9.1 GO:0005901 caveola(GO:0005901)
0.1 7.1 GO:0005811 lipid particle(GO:0005811)
0.1 39.9 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 5.1 GO:0060077 inhibitory synapse(GO:0060077)
0.1 1.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 10.2 GO:0055037 recycling endosome(GO:0055037)
0.1 3.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 9.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 1.2 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128)
0.1 8.6 GO:0043195 terminal bouton(GO:0043195)
0.1 0.8 GO:0030057 desmosome(GO:0030057)
0.1 17.5 GO:0045177 apical part of cell(GO:0045177)
0.1 2.7 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 2.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.9 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 2.2 GO:0008021 synaptic vesicle(GO:0008021)
0.0 31.0 GO:0005576 extracellular region(GO:0005576)
0.0 0.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 5.5 GO:0048471 perinuclear region of cytoplasm(GO:0048471)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
27.0 80.9 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
16.3 81.6 GO:0005534 galactose binding(GO:0005534)
16.3 49.0 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
15.4 46.3 GO:0050656 steroid sulfotransferase activity(GO:0050294) 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
14.8 133.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
13.9 41.8 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
11.5 46.0 GO:0045159 myosin II binding(GO:0045159)
10.8 32.4 GO:0016453 C-acetyltransferase activity(GO:0016453)
10.7 64.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
10.6 42.3 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
9.4 28.2 GO:0004736 pyruvate carboxylase activity(GO:0004736)
8.9 26.7 GO:0035939 microsatellite binding(GO:0035939)
7.6 22.7 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
7.2 79.3 GO:0019870 potassium channel inhibitor activity(GO:0019870)
7.0 55.7 GO:0008172 S-methyltransferase activity(GO:0008172)
6.8 81.6 GO:0070008 serine-type exopeptidase activity(GO:0070008)
6.1 61.2 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
6.1 116.0 GO:0015643 toxic substance binding(GO:0015643)
5.8 40.4 GO:0004111 creatine kinase activity(GO:0004111)
5.6 27.9 GO:0070052 collagen V binding(GO:0070052)
5.5 49.4 GO:0050544 arachidonic acid binding(GO:0050544)
4.9 19.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
4.8 71.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
4.7 19.0 GO:0003872 6-phosphofructokinase activity(GO:0003872)
4.5 18.2 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
4.4 26.4 GO:0035473 lipase binding(GO:0035473)
4.3 12.8 GO:0004046 aminoacylase activity(GO:0004046)
4.3 38.3 GO:0019966 interleukin-1 binding(GO:0019966)
3.7 18.4 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
3.6 42.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
3.4 20.5 GO:0001515 opioid peptide activity(GO:0001515)
3.2 69.6 GO:0005212 structural constituent of eye lens(GO:0005212)
3.1 9.4 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
2.9 14.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
2.6 21.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
2.6 26.0 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
2.5 7.4 GO:0017113 dihydrouracil dehydrogenase (NAD+) activity(GO:0004159) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
2.4 7.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
2.2 44.4 GO:0031005 filamin binding(GO:0031005)
2.2 8.8 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
2.1 25.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
2.1 10.5 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
2.1 66.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
2.1 41.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
2.0 9.9 GO:0030280 structural constituent of epidermis(GO:0030280)
2.0 33.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
2.0 13.7 GO:0071253 connexin binding(GO:0071253)
1.9 11.6 GO:0098821 activin receptor activity, type I(GO:0016361) BMP receptor activity(GO:0098821)
1.9 9.6 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
1.8 9.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
1.8 16.6 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
1.8 10.8 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
1.7 17.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
1.7 12.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
1.7 6.9 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
1.7 6.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
1.7 9.9 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
1.6 28.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
1.6 13.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021) vascular endothelial growth factor binding(GO:0038085)
1.6 8.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
1.6 4.8 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
1.6 64.6 GO:0071855 neuropeptide receptor binding(GO:0071855)
1.6 32.1 GO:0017166 vinculin binding(GO:0017166)
1.5 10.8 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
1.5 21.1 GO:0031748 D1 dopamine receptor binding(GO:0031748)
1.5 8.9 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
1.4 11.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
1.4 37.1 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
1.3 5.4 GO:0004967 glucagon receptor activity(GO:0004967)
1.3 49.2 GO:0030506 ankyrin binding(GO:0030506)
1.2 25.0 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
1.2 6.0 GO:0034235 GPI anchor binding(GO:0034235)
1.2 40.9 GO:0004407 histone deacetylase activity(GO:0004407)
1.2 135.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
1.1 4.5 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
1.1 15.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
1.1 3.3 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
1.1 13.1 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
1.1 13.9 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
1.1 10.6 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
1.1 10.6 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
1.0 31.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
1.0 45.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
1.0 13.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
1.0 14.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.9 33.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.9 3.6 GO:0004743 pyruvate kinase activity(GO:0004743)
0.8 24.9 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.8 13.0 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.8 10.4 GO:0030955 potassium ion binding(GO:0030955)
0.8 5.5 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.8 3.9 GO:0042731 PH domain binding(GO:0042731)
0.8 32.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.6 49.0 GO:0038024 cargo receptor activity(GO:0038024)
0.6 15.2 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.6 3.2 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.6 12.5 GO:0004622 lysophospholipase activity(GO:0004622)
0.6 11.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.6 1.8 GO:0051185 coenzyme transporter activity(GO:0051185)
0.6 16.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.6 13.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.6 8.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.6 37.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.6 7.3 GO:0070097 delta-catenin binding(GO:0070097)
0.6 56.7 GO:0051219 phosphoprotein binding(GO:0051219)
0.6 3.9 GO:0050693 LBD domain binding(GO:0050693)
0.5 8.2 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.5 8.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.5 30.0 GO:0017022 myosin binding(GO:0017022)
0.5 7.9 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.5 3.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.4 75.9 GO:0008237 metallopeptidase activity(GO:0008237)
0.4 7.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.4 2.0 GO:0001849 complement component C1q binding(GO:0001849)
0.4 12.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.4 1.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.4 12.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.3 15.5 GO:0005080 protein kinase C binding(GO:0005080)
0.3 1.9 GO:0004126 cytidine deaminase activity(GO:0004126)
0.3 3.0 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.3 1.8 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.3 1.8 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.3 0.9 GO:0008396 oxysterol 7-alpha-hydroxylase activity(GO:0008396)
0.2 2.6 GO:0005000 vasopressin receptor activity(GO:0005000)
0.2 15.0 GO:0030295 protein kinase activator activity(GO:0030295)
0.2 2.2 GO:0008432 JUN kinase binding(GO:0008432)
0.2 4.3 GO:0005112 Notch binding(GO:0005112)
0.2 0.6 GO:1990254 keratin filament binding(GO:1990254)
0.2 5.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 20.2 GO:0017124 SH3 domain binding(GO:0017124)
0.2 11.4 GO:0005178 integrin binding(GO:0005178)
0.2 11.4 GO:0046332 SMAD binding(GO:0046332)
0.2 8.9 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.2 2.6 GO:0017128 intracellular calcium activated chloride channel activity(GO:0005229) phospholipid scramblase activity(GO:0017128)
0.1 2.9 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 8.1 GO:0030276 clathrin binding(GO:0030276)
0.1 8.6 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 28.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 2.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 0.5 GO:0038181 bile acid receptor activity(GO:0038181)
0.1 1.6 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 4.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 3.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 15.9 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.1 5.4 GO:0019003 GDP binding(GO:0019003)
0.1 6.8 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.1 1.8 GO:0070330 aromatase activity(GO:0070330)
0.1 1.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 7.4 GO:0042626 primary active transmembrane transporter activity(GO:0015399) P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405) ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1 1.8 GO:0042605 peptide antigen binding(GO:0042605)
0.0 5.4 GO:0005179 hormone activity(GO:0005179)
0.0 2.1 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 1.0 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 3.8 GO:0031072 heat shock protein binding(GO:0031072)
0.0 3.5 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 30.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 1.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 2.9 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 8.1 GO:0005509 calcium ion binding(GO:0005509)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 98.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
4.0 40.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
3.6 68.9 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
2.9 49.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
2.6 80.4 PID ALK1 PATHWAY ALK1 signaling events
2.4 89.4 ST P38 MAPK PATHWAY p38 MAPK Pathway
2.0 76.2 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
2.0 399.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
1.9 93.7 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
1.7 26.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
1.5 35.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
1.5 13.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
1.4 24.5 PID AP1 PATHWAY AP-1 transcription factor network
1.0 15.6 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
1.0 50.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.9 10.6 PID S1P S1P2 PATHWAY S1P2 pathway
0.9 36.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.8 13.7 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.7 173.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.7 31.5 PID FGF PATHWAY FGF signaling pathway
0.7 12.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.6 13.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.6 21.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.5 28.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.5 10.5 SIG CHEMOTAXIS Genes related to chemotaxis
0.4 61.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.4 10.9 PID ARF6 PATHWAY Arf6 signaling events
0.3 6.9 PID RAS PATHWAY Regulation of Ras family activation
0.3 5.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.3 10.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.3 7.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.2 9.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.2 11.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.2 1.5 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.2 7.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 1.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 7.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 5.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 4.3 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.2 ST FAS SIGNALING PATHWAY Fas Signaling Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
7.9 71.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
7.4 66.7 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
6.3 133.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
4.6 13.9 REACTOME XENOBIOTICS Genes involved in Xenobiotics
3.6 46.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
3.2 29.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
3.1 52.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
2.7 37.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
2.6 76.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
2.6 47.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
2.4 31.5 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
2.3 135.4 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
2.2 42.7 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
2.1 83.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
1.9 83.2 REACTOME AMYLOIDS Genes involved in Amyloids
1.9 14.9 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
1.9 26.0 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
1.8 32.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
1.7 30.9 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
1.7 80.5 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
1.5 28.0 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
1.3 105.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
1.3 10.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
1.2 19.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
1.1 13.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
1.0 21.1 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
1.0 22.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.9 16.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.9 10.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.7 7.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.7 11.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.7 11.6 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.7 22.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.6 26.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.6 8.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.6 22.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.6 26.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.6 6.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.5 1.5 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.5 4.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.5 6.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.5 42.4 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.5 21.0 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.5 21.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.4 13.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.4 8.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.4 24.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.3 9.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.3 5.0 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.3 52.1 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.3 5.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.2 6.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 5.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 5.4 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.2 3.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2 8.3 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.2 3.0 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 3.1 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 2.9 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.1 1.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 10.9 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 2.1 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 4.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 1.8 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix