Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation
Downloads

Results for Nfia

Z-value: 3.04

Motif logo

Transcription factors associated with Nfia

Gene Symbol Gene ID Gene Info
ENSRNOG00000006966 nuclear factor I/A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfiarn6_v1_chr5_+_116420690_1164206900.481.4e-19Click!

Activity profile of Nfia motif

Sorted Z-values of Nfia motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_159775643 147.09 ENSRNOT00000010939
junctophilin 2
chr1_-_213650247 119.80 ENSRNOT00000019679
cytochrome c oxidase, subunit VIIIb
chr15_+_4077951 115.78 ENSRNOT00000085266
myozenin 1
chr15_-_27815261 105.62 ENSRNOT00000032992
kelch-like family member 33
chr10_+_53778662 99.40 ENSRNOT00000045718
myosin heavy chain 2
chr10_+_86337728 98.90 ENSRNOT00000085408
titin-cap
chr3_-_63568464 97.24 ENSRNOT00000068494

chr9_-_73958480 97.19 ENSRNOT00000017838
myosin, light chain 1
chr17_+_47397558 93.59 ENSRNOT00000085923
ependymin related 1
chrX_-_64715823 88.22 ENSRNOT00000076297
ankyrin repeat and SOCS box-containing 12
chr10_+_53818818 83.17 ENSRNOT00000057260
myosin heavy chain 8
chr1_-_199624783 81.69 ENSRNOT00000026908
cytochrome c oxidase subunit 6A2
chr1_-_104157855 81.42 ENSRNOT00000019311
cysteine and glycine rich protein 3
chr7_-_118108864 81.00 ENSRNOT00000006184
myoglobin
chr13_-_82005741 78.54 ENSRNOT00000076404
methyltransferase like 11B
chr5_+_140888973 78.16 ENSRNOT00000020524
5'-nucleotidase, cytosolic IA
chr1_-_104166367 77.78 ENSRNOT00000092211
cysteine and glycine rich protein 3
chr13_-_90602365 76.19 ENSRNOT00000009344
calsequestrin 1
chr2_-_233743866 75.37 ENSRNOT00000087062
glutamyl aminopeptidase
chrX_+_53053609 74.96 ENSRNOT00000058357
dystrophin
chr8_+_55178289 72.53 ENSRNOT00000059127
crystallin, alpha B
chr13_-_82006005 71.89 ENSRNOT00000039581
methyltransferase like 11B
chr10_+_54352270 67.78 ENSRNOT00000036752
dehydrogenase/reductase 7C
chr10_+_53740841 66.84 ENSRNOT00000004295
myosin heavy chain 2
chr17_-_389967 66.41 ENSRNOT00000023865
fructose-bisphosphatase 2
chr3_-_105512939 66.03 ENSRNOT00000011773
actin, alpha, cardiac muscle 1
chr3_-_37803112 62.33 ENSRNOT00000059461
nebulin
chr18_+_35574002 61.97 ENSRNOT00000093442
ENSRNOT00000070817
ENSRNOT00000093356
myotilin
chr14_-_86047162 61.14 ENSRNOT00000018227
phosphoglycerate mutase 2
chr5_+_152533349 60.36 ENSRNOT00000067524
tripartite motif containing 63
chrX_+_124631881 60.34 ENSRNOT00000009329
ATPase Na+/K+ transporting family member beta 4
chr13_-_52197205 58.66 ENSRNOT00000009712
shisa family member 4
chr7_+_38819771 58.12 ENSRNOT00000006109
lumican
chr14_-_62595854 56.03 ENSRNOT00000003024
Yip1 domain family, member 7
chr1_-_100530183 55.77 ENSRNOT00000067754
myosin binding protein C, fast-type
chr2_-_45518502 54.14 ENSRNOT00000014627
heat shock protein family B (small) member 3
chr3_-_8979889 53.87 ENSRNOT00000065128
carnitine O-acetyltransferase
chr1_-_49844547 52.56 ENSRNOT00000086127
ENSRNOT00000077423
ENSRNOT00000089439
ENSRNOT00000090521

chr5_+_164808323 51.48 ENSRNOT00000011005
natriuretic peptide A
chr13_+_87986240 51.38 ENSRNOT00000003705
regulator of G-protein signaling 5
chr6_-_127248372 50.96 ENSRNOT00000085517
ankyrin repeat and SOCS box-containing 2
chr2_-_184993341 47.90 ENSRNOT00000071580
family with sequence similarity 160, member A1
chr12_-_6740714 47.51 ENSRNOT00000001205
mesenteric estrogen-dependent adipogenesis
chr4_-_147163467 46.77 ENSRNOT00000010748
tissue inhibitor of metalloproteinase 4
chr2_+_104416972 46.76 ENSRNOT00000017125
tripartite motif-containing 55
chr9_-_82008620 46.58 ENSRNOT00000023365
protein kinase AMP-activated non-catalytic subunit gamma 3
chrX_-_142248369 46.42 ENSRNOT00000091330
fibroblast growth factor 13
chr2_+_204512302 46.05 ENSRNOT00000021846
calsequestrin 2
chr10_+_39666991 45.71 ENSRNOT00000030760
acyl-CoA synthetase long-chain family member 6
chr9_-_88356716 44.80 ENSRNOT00000077503
collagen type IV alpha 4 chain
chr4_+_7158970 44.68 ENSRNOT00000037446
ankyrin repeat and SOCS box-containing 10
chr1_+_261281543 43.79 ENSRNOT00000018890
ankyrin repeat domain 2
chr5_-_160179978 42.81 ENSRNOT00000022820
solute carrier family 25, member 34
chr7_+_94375020 42.70 ENSRNOT00000011904
nephroblastoma overexpressed
chr6_+_98284170 42.19 ENSRNOT00000031979
ras homolog family member J
chr5_-_164714145 41.97 ENSRNOT00000055680
mitofusin-2-like
chr9_-_88357182 41.81 ENSRNOT00000041176
collagen type IV alpha 4 chain
chr4_+_155321553 41.59 ENSRNOT00000089614
microfibrillar associated protein 5
chr2_-_184951950 40.27 ENSRNOT00000093486
family with sequence similarity 160, member A1
chr4_+_7076759 40.05 ENSRNOT00000066598
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr10_-_109729019 39.18 ENSRNOT00000054959
protein phosphatase 1, regulatory subunit 27
chrX_-_116792707 39.15 ENSRNOT00000049482
angiomotin
chrX_+_131617798 38.90 ENSRNOT00000074384
proline rich 32
chr17_-_65955606 38.62 ENSRNOT00000067949
ENSRNOT00000023601
ryanodine receptor 2
chr1_-_226935689 37.96 ENSRNOT00000038807
transmembrane protein 109
chr1_-_215536980 37.26 ENSRNOT00000027344
interferon induced transmembrane protein 10
chr5_+_115649046 37.09 ENSRNOT00000041328
glyceraldehyde-3-phosphate dehydrogenase
chr10_+_16970626 37.06 ENSRNOT00000005383
dual specificity phosphatase 1
chr16_+_2537248 36.64 ENSRNOT00000017995
ankyrin repeat and SOCS box-containing 14
chr4_+_7158448 36.59 ENSRNOT00000076953
ankyrin repeat and SOCS box-containing 10
chr18_-_63825408 36.51 ENSRNOT00000043709
similar to glyceraldehyde-3-phosphate dehydrogenase
chr4_+_180062799 36.28 ENSRNOT00000021623
Ras association domain family member 8
chr13_+_113691932 36.04 ENSRNOT00000084709
CD34 molecule
chr14_+_6994190 35.85 ENSRNOT00000020357
SPARC like 1
chr17_-_84614228 35.35 ENSRNOT00000043042

chr8_-_22542997 35.32 ENSRNOT00000061009
transmembrane p24 trafficking protein 1
chr8_-_116349896 35.04 ENSRNOT00000087306
leucine-rich single-pass membrane protein 2
chr20_-_2701637 34.90 ENSRNOT00000049667
heat shock protein family A (Hsp70) member 1A
chr17_-_14717420 34.80 ENSRNOT00000071131
extracellular matrix protein 2-like
chrX_+_77278240 34.44 ENSRNOT00000085653
phosphoglycerate kinase 1
chr17_+_15966234 34.28 ENSRNOT00000084304
WNK lysine deficient protein kinase 2
chr8_+_130009573 33.67 ENSRNOT00000026106
trafficking kinesin protein 1
chr13_+_83073544 33.59 ENSRNOT00000066119
ENSRNOT00000079796
ENSRNOT00000077070
dermatopontin
chr1_-_82452281 33.39 ENSRNOT00000027995
branched chain ketoacid dehydrogenase E1, alpha polypeptide
chr16_+_25773602 33.33 ENSRNOT00000047750
glyceraldehyde-3-phosphate dehydrogenase, pseudogene 2
chr6_-_8344897 33.06 ENSRNOT00000082353
prolyl endopeptidase-like
chrX_-_116792864 32.96 ENSRNOT00000090918
angiomotin
chr11_+_70687500 32.64 ENSRNOT00000037432

chr10_+_13836128 32.27 ENSRNOT00000012720
phosphoglycolate phosphatase
chr8_+_117268337 32.17 ENSRNOT00000072098
ENSRNOT00000083578
laminin subunit beta 2
chr4_-_97784842 32.15 ENSRNOT00000007698
growth arrest and DNA-damage-inducible, alpha
chr6_-_8344574 32.01 ENSRNOT00000009660
prolyl endopeptidase-like
chr10_+_89251370 31.88 ENSRNOT00000076820
amine oxidase, copper containing 3
chr3_+_57770948 31.40 ENSRNOT00000038429

chr8_-_95387363 31.32 ENSRNOT00000014657
T-box18
chr20_+_5008508 31.20 ENSRNOT00000001153
von Willebrand factor A domain containing 7
chr5_-_152458023 31.00 ENSRNOT00000031225
connector enhancer of kinase suppressor of Ras 1
chr10_+_65767930 30.70 ENSRNOT00000039954
vitronectin
chr3_+_148386189 30.39 ENSRNOT00000011255
myosin light chain kinase 2
chr12_-_23954431 30.35 ENSRNOT00000001958
malate dehydrogenase 2
chr15_-_52214616 30.22 ENSRNOT00000015035
surfactant protein C
chr13_+_83073866 29.97 ENSRNOT00000075996
dermatopontin
chr2_+_188528979 29.94 ENSRNOT00000087934
thrombospondin 3
chr1_-_259484569 29.83 ENSRNOT00000021289
ENSRNOT00000021114
ENSRNOT00000021229
ENSRNOT00000021347
ENSRNOT00000021226
sorbin and SH3 domain containing 1
chr15_-_108120279 29.74 ENSRNOT00000090572
dedicator of cytokinesis 9
chr4_+_145427367 29.62 ENSRNOT00000037788
interleukin 17 receptor C
chr5_+_104698040 29.57 ENSRNOT00000009127
ADAMTS-like 1
chr5_+_151692108 29.51 ENSRNOT00000086144
family with sequence similarity 46, member B
chr20_-_4879779 29.35 ENSRNOT00000081924
heat shock protein family A (Hsp70) member 1B
chr2_-_197860699 29.32 ENSRNOT00000028740
extracellular matrix protein 1
chr16_+_6962722 29.15 ENSRNOT00000023330
musculoskeletal, embryonic nuclear protein 1
chr1_+_137799185 29.13 ENSRNOT00000083590
ENSRNOT00000092778
ATP/GTP binding protein-like 1
chr19_+_27404712 29.00 ENSRNOT00000023657
myosin light chain kinase 3
chr1_-_215033460 28.69 ENSRNOT00000044565
dual specificity phosphatase 8
chr5_-_64850427 28.35 ENSRNOT00000008883
transmembrane protein 246
chr19_-_9777465 28.05 ENSRNOT00000017413
NDRG family member 4
chr17_-_13393243 28.00 ENSRNOT00000018252
growth arrest and DNA-damage-inducible, gamma
chr18_-_15540177 27.85 ENSRNOT00000022113
transthyretin
chr10_+_47765432 27.65 ENSRNOT00000078231
microfibril-associated glycoprotein 4-like
chr16_+_54332660 27.46 ENSRNOT00000037685
microtubule associated tumor suppressor 1
chr2_+_60920257 27.30 ENSRNOT00000025170
C1q and tumor necrosis factor related protein 3
chr18_-_57201740 26.78 ENSRNOT00000026227
actin binding LIM protein family, member 3
chr2_-_231521052 26.37 ENSRNOT00000089534
ENSRNOT00000080470
ENSRNOT00000084756
ankyrin 2
chr7_+_2752680 26.34 ENSRNOT00000033726
citrate synthase
chr2_-_180914940 26.25 ENSRNOT00000015732
tryptophan 2,3-dioxygenase
chr13_+_52662996 25.99 ENSRNOT00000047682
troponin T2, cardiac type
chr1_+_199941161 25.88 ENSRNOT00000027616
Bcl2-associated athanogene 3
chr8_+_119228612 25.83 ENSRNOT00000078439
ENSRNOT00000043737
leucine rich repeat containing 2
chr4_-_112357484 25.38 ENSRNOT00000057854

chr20_-_2701815 25.17 ENSRNOT00000061950
heat shock protein family A (Hsp70) member 1A
chr14_-_13058172 24.86 ENSRNOT00000002746
ENSRNOT00000071706
PR/SET domain 8
chr19_+_25095089 24.72 ENSRNOT00000041717
protein kinase cAMP-activated catalytic subunit alpha
chr4_+_44597123 23.99 ENSRNOT00000078250
caveolin 1
chr6_-_108076186 23.94 ENSRNOT00000014814
family with sequence similarity 161, member B
chr15_+_102164751 23.61 ENSRNOT00000076400
glypican 6
chr20_+_6923489 23.43 ENSRNOT00000093373
ENSRNOT00000000632
peptidase inhibitor 16
chr6_+_108076306 23.31 ENSRNOT00000014913
coenzyme Q6 monooxygenase
chr1_-_170404056 23.29 ENSRNOT00000024402
amyloid beta precursor protein binding family B member 1
chr13_-_105140473 23.24 ENSRNOT00000087023
transforming growth factor, beta 2
chr1_-_275882444 23.24 ENSRNOT00000083215
glycerol-3-phosphate acyltransferase, mitochondrial
chr10_+_63659085 23.10 ENSRNOT00000005039
Rab interacting lysosomal protein
chr3_+_72540538 23.10 ENSRNOT00000012379
apelin receptor
chr2_+_11658568 23.04 ENSRNOT00000076408
ENSRNOT00000076416
ENSRNOT00000076992
ENSRNOT00000075931
ENSRNOT00000076136
ENSRNOT00000076481
ENSRNOT00000076084
ENSRNOT00000076230
ENSRNOT00000076710
ENSRNOT00000076239
myocyte enhancer factor 2C
chr4_+_71836677 22.53 ENSRNOT00000024048
taste receptor, type 2, member 126
chr2_-_187863349 22.18 ENSRNOT00000084455
lamin A/C
chr1_-_275906686 22.18 ENSRNOT00000092170
glycerol-3-phosphate acyltransferase, mitochondrial
chr14_+_38247791 22.17 ENSRNOT00000064128
corin, serine peptidase
chr9_-_55256340 22.07 ENSRNOT00000028907
serum deprivation response
chr4_-_163214678 21.89 ENSRNOT00000091602
C-type lectin domain family 1, member A
chr4_+_56625561 21.88 ENSRNOT00000008356
ENSRNOT00000090808
ENSRNOT00000008972
calumenin
chr1_-_215536770 21.86 ENSRNOT00000078030
interferon induced transmembrane protein 10
chr3_+_140024043 21.84 ENSRNOT00000086409
Ras and Rab interactor 2
chr20_-_45053640 21.81 ENSRNOT00000072256
similar to Na+ dependent glucose transporter 1
chr7_-_135630654 21.74 ENSRNOT00000047388
ENSRNOT00000088223
ENSRNOT00000074793
ADAM metallopeptidase with thrombospondin type 1 motif, 20
chr2_+_222792999 21.39 ENSRNOT00000036228

chr7_+_144595960 21.35 ENSRNOT00000021909
homeobox C9
chr17_-_15566332 21.31 ENSRNOT00000093743
extracellular matrix protein 2
chr16_-_81880502 21.26 ENSRNOT00000079096
MCF.2 cell line derived transforming sequence-like
chr1_+_84304228 21.21 ENSRNOT00000024771
periaxin
chr3_+_160207913 21.15 ENSRNOT00000014346
WNT1 inducible signaling pathway protein 2
chr4_-_89281222 21.14 ENSRNOT00000010898
family with sequence similarity 13, member A
chr15_+_110114148 21.11 ENSRNOT00000006264
integrin subunit beta like 1
chr1_-_162385575 20.82 ENSRNOT00000016540
thyroid hormone responsive
chr1_+_101012822 20.63 ENSRNOT00000027809
related RAS viral (r-ras) oncogene homolog
chr1_+_144239020 20.53 ENSRNOT00000032106
ADAMTS-like 3
chr14_-_60964324 20.29 ENSRNOT00000005155
superoxide dismutase 3, extracellular
chr5_-_139749050 20.21 ENSRNOT00000056651
nuclear transcription factor Y subunit gamma
chr14_+_83560541 20.10 ENSRNOT00000057738
ENSRNOT00000085228
phosphoinositide-3-kinase interacting protein 1
chr1_-_24056373 20.01 ENSRNOT00000015566
solute carrier family 2 member 12
chr4_-_71893306 19.89 ENSRNOT00000077710
olfactory receptor 803
chr4_-_84768249 19.57 ENSRNOT00000013205
FK506 binding protein 14
chr20_+_5050327 19.47 ENSRNOT00000083353
dimethylarginine dimethylaminohydrolase 2
chr20_+_27954433 19.29 ENSRNOT00000064288
LIM zinc finger domain containing 1
chr2_+_256609787 19.19 ENSRNOT00000047564
ENSRNOT00000088437
adhesion G protein-coupled receptor L4
chr8_-_107952530 19.19 ENSRNOT00000052043
claudin 18
chr14_+_60857989 19.12 ENSRNOT00000034411
coiled-coil domain containing 149
chr15_+_10120206 19.08 ENSRNOT00000033048
retinoic acid receptor, beta
chr5_-_64789318 19.04 ENSRNOT00000078957
mitochondrial ribosomal protein L50
chr3_-_48536235 18.82 ENSRNOT00000083536
fibroblast activation protein, alpha
chr15_+_23665202 18.75 ENSRNOT00000089226
sterile alpha motif domain containing 4A
chr10_+_45659143 18.50 ENSRNOT00000058327
wingless-type MMTV integration site family, member 9A
chr1_-_250626844 18.31 ENSRNOT00000077135
N-acylsphingosine amidohydrolase 2
chr10_+_46972038 18.21 ENSRNOT00000023838
mitochondrial elongation factor 2
chr9_-_83253458 18.15 ENSRNOT00000041689
Eph receptor A4
chr8_-_105462141 18.15 ENSRNOT00000066731
ENSRNOT00000078760
calsyntenin 2
chr13_-_80738634 18.10 ENSRNOT00000081551
flavin containing monooxygenase 1
chr2_-_172361779 18.10 ENSRNOT00000085876
schwannomin interacting protein 1
chr2_-_30246010 18.10 ENSRNOT00000023900
methylcrotonoyl-CoA carboxylase 2
chr2_+_142262236 17.92 ENSRNOT00000019057
lipoma HMGIC fusion partner
chr17_+_75190783 17.88 ENSRNOT00000085840

chr3_+_11679530 17.75 ENSRNOT00000074562
ENSRNOT00000071801
endoglin
chr12_+_23752844 17.70 ENSRNOT00000001953
scavenger receptor cysteine rich family member with 4 domains
chr16_+_59077574 17.63 ENSRNOT00000090477
DLC1 Rho GTPase activating protein
chr13_-_80775230 17.62 ENSRNOT00000091389
ENSRNOT00000004762
flavin containing monooxygenase 2
chr7_-_143523457 17.56 ENSRNOT00000012943
ENSRNOT00000082264
keratin 4
chr10_+_62191656 17.56 ENSRNOT00000029866
SET and MYND domain containing 4
chr19_+_61332351 17.55 ENSRNOT00000014492
neuropilin 1
chr13_+_57131395 17.54 ENSRNOT00000017884
potassium sodium-activated channel subfamily T member 2
chr19_+_16417817 17.43 ENSRNOT00000015272
iroquois homeobox 5
chr16_+_6970342 17.38 ENSRNOT00000061294
ENSRNOT00000048344
inter-alpha-trypsin inhibitor heavy chain family, member 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfia

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
64.5 258.1 GO:0035995 detection of muscle stretch(GO:0035995)
50.1 150.4 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
37.8 151.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
29.8 89.4 GO:0031439 positive regulation of mRNA cleavage(GO:0031439) positive regulation of endoribonuclease activity(GO:1902380) positive regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904722)
27.0 81.0 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
24.0 72.1 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
22.0 66.0 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
21.0 147.1 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
17.2 51.5 GO:1902304 positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of potassium ion export(GO:1902304)
16.8 201.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
16.6 66.4 GO:0046351 disaccharide biosynthetic process(GO:0046351)
15.4 184.4 GO:0001778 plasma membrane repair(GO:0001778)
15.2 45.7 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
15.1 75.4 GO:0002003 angiotensin maturation(GO:0002003)
14.2 42.7 GO:1904057 negative regulation of SMAD protein import into nucleus(GO:0060392) negative regulation of sensory perception of pain(GO:1904057)
14.0 139.5 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
13.5 53.9 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
13.0 65.0 GO:0098907 regulation of SA node cell action potential(GO:0098907)
12.4 37.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
12.3 36.8 GO:1904178 sterol regulatory element binding protein import into nucleus(GO:0035105) negative regulation of adipose tissue development(GO:1904178)
12.1 60.4 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
12.0 36.0 GO:0035759 mesangial cell-matrix adhesion(GO:0035759) positive regulation of granulocyte colony-stimulating factor production(GO:0071657) metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254) positive regulation of macrophage colony-stimulating factor production(GO:1901258)
12.0 24.0 GO:1903598 positive regulation of gap junction assembly(GO:1903598)
10.7 74.6 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
10.6 31.9 GO:0010796 regulation of multivesicular body size(GO:0010796)
10.4 31.3 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
10.4 51.8 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
10.0 40.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
10.0 40.0 GO:0006114 glycerol biosynthetic process(GO:0006114)
9.8 9.8 GO:1903596 regulation of gap junction assembly(GO:1903596)
9.2 46.0 GO:0071313 cellular response to caffeine(GO:0071313)
9.1 118.8 GO:0032836 glomerular basement membrane development(GO:0032836)
9.1 72.5 GO:0007021 tubulin complex assembly(GO:0007021)
8.9 35.4 GO:1902730 positive regulation of proteoglycan biosynthetic process(GO:1902730)
7.9 39.7 GO:0003274 endocardial cushion fusion(GO:0003274)
7.7 23.0 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
7.4 22.2 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
7.3 36.3 GO:0034334 adherens junction maintenance(GO:0034334)
7.3 29.0 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
7.2 50.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
7.1 78.2 GO:0046085 purine nucleoside monophosphate catabolic process(GO:0009128) adenosine metabolic process(GO:0046085)
7.1 21.2 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
6.9 20.7 GO:0097187 dentinogenesis(GO:0097187)
6.6 46.4 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
6.6 19.8 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
6.5 13.1 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
6.4 19.2 GO:2001205 negative regulation of osteoclast development(GO:2001205)
6.3 18.8 GO:0097325 melanocyte proliferation(GO:0097325)
6.3 31.3 GO:0003228 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
6.2 31.2 GO:1904008 response to monosodium glutamate(GO:1904008)
6.2 55.8 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
6.2 67.8 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
6.0 18.1 GO:2001106 fasciculation of motor neuron axon(GO:0097156) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
6.0 30.2 GO:0050828 regulation of liquid surface tension(GO:0050828)
6.0 18.1 GO:0006552 leucine catabolic process(GO:0006552)
5.9 17.6 GO:0061441 vestibulocochlear nerve structural organization(GO:0021649) neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) renal artery morphogenesis(GO:0061441) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835)
5.4 16.1 GO:0042560 folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
5.1 15.2 GO:0048749 compound eye development(GO:0048749)
5.0 45.4 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
4.9 14.7 GO:0097498 endothelial tube lumen extension(GO:0097498)
4.9 14.7 GO:0019417 sulfur oxidation(GO:0019417)
4.9 29.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
4.7 9.4 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023) kidney smooth muscle tissue development(GO:0072194)
4.5 13.6 GO:0044330 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330)
4.4 53.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
4.4 17.6 GO:0072592 oxygen metabolic process(GO:0072592)
4.4 13.2 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
4.1 12.4 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
4.1 24.7 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
4.1 16.4 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
4.0 12.0 GO:0070814 hydrogen sulfide biosynthetic process(GO:0070814)
3.8 26.7 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
3.7 14.9 GO:0052203 modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
3.6 21.7 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
3.6 61.3 GO:0071850 mitotic cell cycle arrest(GO:0071850)
3.5 10.6 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
3.5 7.0 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
3.4 13.7 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
3.4 27.3 GO:0070162 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
3.4 10.2 GO:0042726 flavin-containing compound metabolic process(GO:0042726) positive regulation of ubiquitin-specific protease activity(GO:2000158)
3.4 43.8 GO:2000291 regulation of myoblast proliferation(GO:2000291)
3.4 16.8 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
3.3 23.4 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
3.3 10.0 GO:1903849 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
3.3 16.7 GO:0001582 detection of chemical stimulus involved in sensory perception of sweet taste(GO:0001582)
3.3 23.3 GO:0043587 tongue morphogenesis(GO:0043587)
3.3 9.9 GO:1903699 tarsal gland development(GO:1903699)
3.2 32.4 GO:0060973 cell migration involved in heart development(GO:0060973)
3.2 9.6 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
3.2 9.5 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
3.1 115.8 GO:0030239 myofibril assembly(GO:0030239)
3.0 6.1 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
3.0 33.4 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
3.0 32.8 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
3.0 3.0 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
3.0 32.6 GO:0070327 thyroid hormone transport(GO:0070327)
2.9 58.6 GO:0003417 growth plate cartilage development(GO:0003417)
2.9 8.8 GO:0001928 regulation of exocyst assembly(GO:0001928)
2.9 8.7 GO:0045959 negative regulation of complement activation, classical pathway(GO:0045959)
2.9 54.5 GO:0006107 oxaloacetate metabolic process(GO:0006107)
2.7 8.0 GO:0048014 Tie signaling pathway(GO:0048014)
2.6 18.5 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
2.6 10.5 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
2.5 10.1 GO:1990375 baculum development(GO:1990375)
2.5 25.3 GO:0021540 corpus callosum morphogenesis(GO:0021540)
2.5 12.5 GO:0036438 maintenance of lens transparency(GO:0036438)
2.4 12.2 GO:1905050 positive regulation of metallopeptidase activity(GO:1905050)
2.4 19.3 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
2.4 21.4 GO:0019896 axonal transport of mitochondrion(GO:0019896)
2.3 11.5 GO:0016098 monoterpenoid metabolic process(GO:0016098)
2.3 20.6 GO:0044351 macropinocytosis(GO:0044351)
2.3 29.6 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
2.2 13.3 GO:1990928 response to amino acid starvation(GO:1990928)
2.2 13.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
2.2 6.6 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
2.2 6.6 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
2.1 6.4 GO:0043060 meiotic metaphase I plate congression(GO:0043060)
2.0 18.1 GO:0070995 NADPH oxidation(GO:0070995)
2.0 31.9 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
2.0 5.9 GO:0006296 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
1.9 11.7 GO:0051204 protein insertion into mitochondrial membrane(GO:0051204)
1.9 74.0 GO:0030199 collagen fibril organization(GO:0030199)
1.9 9.5 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
1.9 7.6 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
1.9 9.4 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
1.9 42.9 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
1.9 46.4 GO:0097435 fibril organization(GO:0097435)
1.8 9.2 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.8 34.3 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
1.8 5.3 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
1.8 19.5 GO:0006527 arginine catabolic process(GO:0006527)
1.8 54.7 GO:0008053 mitochondrial fusion(GO:0008053)
1.7 28.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
1.7 12.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
1.7 8.3 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
1.6 8.2 GO:0071409 cellular response to cycloheximide(GO:0071409)
1.6 13.0 GO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332)
1.6 16.3 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
1.6 8.0 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
1.6 29.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
1.5 9.3 GO:0038161 prolactin signaling pathway(GO:0038161)
1.5 29.3 GO:0030502 negative regulation of bone mineralization(GO:0030502)
1.4 15.6 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
1.4 7.0 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
1.4 16.6 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
1.4 12.3 GO:0006105 succinate metabolic process(GO:0006105)
1.3 21.4 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
1.3 1.3 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
1.3 14.7 GO:0045792 negative regulation of cell size(GO:0045792)
1.3 4.0 GO:0032289 central nervous system myelin formation(GO:0032289)
1.3 9.1 GO:0001661 conditioned taste aversion(GO:0001661)
1.3 20.8 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
1.3 5.2 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
1.3 6.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
1.3 17.6 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
1.2 3.7 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
1.2 10.6 GO:0061303 cornea development in camera-type eye(GO:0061303)
1.1 12.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
1.1 53.4 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
1.1 3.4 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
1.1 12.4 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
1.1 27.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
1.1 5.5 GO:0034163 regulation of toll-like receptor 9 signaling pathway(GO:0034163)
1.1 20.3 GO:0019430 removal of superoxide radicals(GO:0019430)
1.1 18.1 GO:0048745 smooth muscle tissue development(GO:0048745)
1.1 4.3 GO:0010916 regulation of phosphatidylcholine catabolic process(GO:0010899) regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
1.0 54.4 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
1.0 3.0 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
1.0 2.0 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.9 8.5 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.9 8.3 GO:0051195 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.9 8.9 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.9 14.9 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.9 6.1 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.8 23.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.8 80.0 GO:0060048 cardiac muscle contraction(GO:0060048)
0.8 18.7 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.8 2.4 GO:1904045 cellular response to aldosterone(GO:1904045)
0.8 8.9 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.8 2.4 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.8 9.4 GO:0042737 drug catabolic process(GO:0042737)
0.8 29.2 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.8 6.9 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.8 4.6 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) negative regulation by host of viral genome replication(GO:0044828)
0.8 48.7 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.7 1.5 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.7 8.1 GO:0061050 regulation of cell growth involved in cardiac muscle cell development(GO:0061050) positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.7 5.8 GO:0035330 regulation of hippo signaling(GO:0035330)
0.7 14.6 GO:0002347 response to tumor cell(GO:0002347)
0.7 9.4 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.7 10.0 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.7 4.8 GO:0060736 prostate gland growth(GO:0060736)
0.7 10.3 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.7 2.0 GO:0097167 circadian regulation of translation(GO:0097167)
0.7 37.0 GO:0006094 gluconeogenesis(GO:0006094)
0.7 3.3 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.7 7.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.6 1.9 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.6 5.1 GO:0003416 endochondral bone growth(GO:0003416) bone growth(GO:0098868)
0.6 4.5 GO:0071352 cellular response to interleukin-2(GO:0071352)
0.6 12.9 GO:0050873 brown fat cell differentiation(GO:0050873)
0.6 20.1 GO:0048662 negative regulation of smooth muscle cell proliferation(GO:0048662)
0.6 6.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.6 11.0 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.5 8.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.5 15.0 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.5 19.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.5 39.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.5 4.8 GO:0016266 O-glycan processing(GO:0016266)
0.5 3.3 GO:0090394 negative regulation of excitatory postsynaptic potential(GO:0090394)
0.4 3.1 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.4 4.9 GO:0007097 nuclear migration(GO:0007097)
0.4 22.0 GO:0050909 sensory perception of taste(GO:0050909)
0.4 21.3 GO:0008542 visual learning(GO:0008542)
0.4 12.7 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.4 12.3 GO:0042417 dopamine metabolic process(GO:0042417)
0.4 1.9 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.4 7.0 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.4 1.1 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.4 468.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.4 1.1 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.3 2.7 GO:0008063 Toll signaling pathway(GO:0008063)
0.3 8.5 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.3 4.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.3 14.1 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.3 1.0 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.3 3.0 GO:0050957 equilibrioception(GO:0050957)
0.3 3.2 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.3 22.2 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.3 3.2 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.3 35.1 GO:0007160 cell-matrix adhesion(GO:0007160)
0.3 12.3 GO:0009060 aerobic respiration(GO:0009060)
0.3 4.5 GO:0061157 mRNA destabilization(GO:0061157)
0.3 0.6 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.3 1.2 GO:0044691 tooth eruption(GO:0044691)
0.3 3.4 GO:0042574 retinal metabolic process(GO:0042574)
0.3 5.0 GO:0036158 outer dynein arm assembly(GO:0036158)
0.3 0.3 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.3 2.2 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.3 24.7 GO:1903955 positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)
0.3 17.0 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.3 6.9 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.3 5.2 GO:0003351 epithelial cilium movement(GO:0003351)
0.3 7.4 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.3 24.8 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.3 1.0 GO:0071872 cellular response to epinephrine stimulus(GO:0071872)
0.2 20.6 GO:0045766 positive regulation of angiogenesis(GO:0045766)
0.2 0.7 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.2 2.6 GO:0008090 retrograde axonal transport(GO:0008090)
0.2 4.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.2 2.7 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.2 3.2 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.2 1.1 GO:0033504 floor plate development(GO:0033504)
0.2 1.6 GO:0061548 ganglion development(GO:0061548)
0.2 1.9 GO:0007288 sperm axoneme assembly(GO:0007288)
0.2 0.5 GO:0072189 ureter development(GO:0072189)
0.2 5.6 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.2 0.8 GO:0006842 tricarboxylic acid transport(GO:0006842)
0.1 13.7 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.1 2.4 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1 12.8 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 0.9 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 9.4 GO:0006006 glucose metabolic process(GO:0006006)
0.1 4.0 GO:0035904 aorta development(GO:0035904)
0.1 4.3 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 25.1 GO:0006813 potassium ion transport(GO:0006813)
0.1 16.4 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.1 2.0 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 1.6 GO:0045776 negative regulation of blood pressure(GO:0045776)
0.1 0.8 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 4.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.4 GO:0021936 regulation of cerebellar granule cell precursor proliferation(GO:0021936)
0.0 1.7 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 1.5 GO:0042220 response to cocaine(GO:0042220)
0.0 2.2 GO:0060135 maternal process involved in female pregnancy(GO:0060135)
0.0 0.2 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.3 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.5 GO:0098880 maintenance of postsynaptic specialization structure(GO:0098880) maintenance of postsynaptic density structure(GO:0099562)
0.0 1.0 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 2.5 GO:2000278 regulation of DNA biosynthetic process(GO:2000278)
0.0 1.1 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 2.4 GO:0006664 glycolipid metabolic process(GO:0006664)
0.0 0.3 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0030033 microvillus assembly(GO:0030033)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
36.0 144.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
22.6 67.8 GO:0014801 longitudinal sarcoplasmic reticulum(GO:0014801)
18.5 166.2 GO:0005826 actomyosin contractile ring(GO:0005826)
18.4 147.1 GO:0030314 junctional membrane complex(GO:0030314)
13.9 55.8 GO:0005859 muscle myosin complex(GO:0005859)
12.6 201.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
12.2 97.7 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
10.9 98.5 GO:0097512 cardiac myofibril(GO:0097512)
9.9 29.8 GO:0005899 insulin receptor complex(GO:0005899)
7.3 29.4 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
7.2 93.7 GO:0032982 myosin filament(GO:0032982)
6.7 33.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
6.4 51.0 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
6.4 19.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
6.0 71.8 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
5.6 889.8 GO:0031674 I band(GO:0031674)
5.4 75.4 GO:0031983 vesicle lumen(GO:0031983)
5.4 32.2 GO:0005608 laminin-3 complex(GO:0005608)
5.1 30.7 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
5.0 60.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
4.6 37.1 GO:0097452 GAIT complex(GO:0097452)
4.6 36.8 GO:0005638 lamin filament(GO:0005638)
4.5 31.3 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
4.1 12.3 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) fumarate reductase complex(GO:0045283)
3.3 40.1 GO:0071564 npBAF complex(GO:0071564)
3.3 16.7 GO:1903768 sweet taste receptor complex(GO:1903767) taste receptor complex(GO:1903768)
3.3 16.4 GO:0048179 activin receptor complex(GO:0048179)
3.2 34.9 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
3.0 24.0 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
2.9 8.8 GO:0000814 ESCRT II complex(GO:0000814)
2.9 38.0 GO:0002199 zona pellucida receptor complex(GO:0002199)
2.9 20.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
2.7 24.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
2.6 39.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
2.6 12.9 GO:0005610 laminin-5 complex(GO:0005610)
2.6 46.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
2.3 97.2 GO:0016459 myosin complex(GO:0016459)
2.2 15.6 GO:0001652 granular component(GO:0001652)
2.2 4.5 GO:0036396 MIS complex(GO:0036396)
2.2 17.6 GO:0097443 sorting endosome(GO:0097443)
2.2 30.2 GO:0097208 alveolar lamellar body(GO:0097208)
2.1 10.7 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
2.1 6.4 GO:0005712 chiasma(GO:0005712) recombination nodule(GO:0005713)
2.1 10.5 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
2.0 53.4 GO:0042629 mast cell granule(GO:0042629)
2.0 5.9 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
1.9 72.0 GO:0008180 COP9 signalosome(GO:0008180)
1.8 14.7 GO:0031931 TORC1 complex(GO:0031931)
1.8 9.1 GO:0035976 AP1 complex(GO:0035976)
1.7 6.8 GO:0001405 presequence translocase-associated import motor(GO:0001405)
1.7 13.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
1.4 9.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
1.3 12.1 GO:0000138 Golgi trans cisterna(GO:0000138)
1.2 7.4 GO:0070847 core mediator complex(GO:0070847)
1.2 7.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
1.1 33.6 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
1.1 16.8 GO:0005605 basal lamina(GO:0005605)
1.1 46.4 GO:0014704 intercalated disc(GO:0014704)
1.1 63.9 GO:0030017 sarcomere(GO:0030017)
1.1 53.8 GO:0009925 basal plasma membrane(GO:0009925)
1.1 21.3 GO:0005614 interstitial matrix(GO:0005614)
1.0 10.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
1.0 2.9 GO:1990836 lysosomal matrix(GO:1990836)
0.9 46.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.7 1.5 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.7 34.0 GO:0016235 aggresome(GO:0016235)
0.7 12.2 GO:0031527 filopodium membrane(GO:0031527)
0.7 117.4 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.7 34.6 GO:1904115 axon cytoplasm(GO:1904115)
0.7 20.4 GO:0005921 gap junction(GO:0005921)
0.7 4.9 GO:0042641 actomyosin(GO:0042641)
0.7 47.4 GO:0005604 basement membrane(GO:0005604)
0.7 3.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.7 35.1 GO:0005581 collagen trimer(GO:0005581)
0.6 137.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.6 9.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.6 33.9 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.6 4.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.5 7.0 GO:0060091 kinocilium(GO:0060091)
0.5 13.2 GO:0045178 basal part of cell(GO:0045178)
0.4 4.5 GO:0000974 Prp19 complex(GO:0000974)
0.4 4.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.4 13.7 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.4 11.7 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.4 137.1 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.4 9.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.3 29.3 GO:0005902 microvillus(GO:0005902)
0.3 23.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.3 7.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.3 21.0 GO:0045095 keratin filament(GO:0045095)
0.3 1.4 GO:0044327 dendritic spine head(GO:0044327)
0.3 42.2 GO:0031012 extracellular matrix(GO:0031012)
0.3 1.6 GO:0033268 node of Ranvier(GO:0033268)
0.2 7.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.2 1.2 GO:0032420 stereocilium(GO:0032420)
0.2 1.9 GO:0032433 filopodium tip(GO:0032433)
0.2 18.5 GO:0005901 caveola(GO:0005901)
0.2 4.6 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.2 41.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.2 1.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.2 21.4 GO:0043195 terminal bouton(GO:0043195)
0.2 56.6 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.2 13.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.2 13.3 GO:0016324 apical plasma membrane(GO:0016324)
0.2 10.7 GO:0031902 late endosome membrane(GO:0031902)
0.2 12.9 GO:0043209 myelin sheath(GO:0043209)
0.2 1.0 GO:0000322 storage vacuole(GO:0000322)
0.2 14.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 1.0 GO:0070852 cell body fiber(GO:0070852)
0.1 25.8 GO:0000323 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1 4.5 GO:0030175 filopodium(GO:0030175)
0.1 6.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 0.7 GO:0031415 NatA complex(GO:0031415)
0.1 0.9 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 8.1 GO:0005770 late endosome(GO:0005770)
0.1 53.8 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 2.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 3.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 1.0 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 1.9 GO:0032040 small-subunit processome(GO:0032040)
0.1 19.3 GO:0016607 nuclear speck(GO:0016607)
0.1 0.3 GO:0043194 axon initial segment(GO:0043194)
0.1 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 4.9 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 64.3 GO:0070062 extracellular exosome(GO:0070062)
0.0 242.8 GO:0016021 integral component of membrane(GO:0016021)
0.0 1.7 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 12.0 GO:0005794 Golgi apparatus(GO:0005794)
0.0 3.5 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.3 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
50.7 203.0 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
50.1 150.4 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
42.9 214.7 GO:0051373 FATZ binding(GO:0051373)
29.8 89.4 GO:0031249 denatured protein binding(GO:0031249)
15.3 61.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
14.8 59.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
14.4 72.1 GO:0043532 angiostatin binding(GO:0043532)
12.4 37.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
11.5 34.4 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
10.5 147.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
9.8 48.8 GO:0070052 collagen V binding(GO:0070052)
9.7 38.6 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
9.3 37.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
8.9 26.7 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
7.6 30.4 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
7.6 45.4 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
6.7 53.9 GO:0016413 O-acetyltransferase activity(GO:0016413)
6.7 201.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
6.6 19.8 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
6.5 26.0 GO:0030172 troponin C binding(GO:0030172)
6.5 19.5 GO:0016403 dimethylargininase activity(GO:0016403)
6.2 24.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
5.9 29.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
5.5 60.4 GO:0031432 titin binding(GO:0031432)
5.4 65.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
5.4 81.0 GO:0005344 oxygen transporter activity(GO:0005344)
5.3 26.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
5.0 105.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
4.6 78.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
4.5 13.6 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
4.5 36.0 GO:0043199 sulfate binding(GO:0043199)
4.5 13.4 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
4.4 13.2 GO:0035939 microsatellite binding(GO:0035939)
4.3 55.8 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
4.3 93.7 GO:0000146 microfilament motor activity(GO:0000146)
4.2 50.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
4.1 12.3 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
4.1 16.3 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
4.1 20.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
4.0 12.0 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
3.9 11.8 GO:0031711 bradykinin receptor binding(GO:0031711)
3.8 68.9 GO:0050308 sugar-phosphatase activity(GO:0050308)
3.8 45.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
3.8 45.1 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
3.7 86.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
3.7 33.4 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
3.7 29.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
3.6 18.1 GO:0042731 PH domain binding(GO:0042731)
3.5 17.7 GO:0005534 galactose binding(GO:0005534)
3.4 10.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
3.3 16.7 GO:0033041 sweet taste receptor activity(GO:0033041)
3.3 32.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
3.2 70.9 GO:0004745 retinol dehydrogenase activity(GO:0004745)
3.1 12.5 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
3.1 9.3 GO:0004925 prolactin receptor activity(GO:0004925)
3.1 18.3 GO:0017040 ceramidase activity(GO:0017040)
3.0 87.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
3.0 65.5 GO:0005212 structural constituent of eye lens(GO:0005212)
2.9 31.9 GO:0008131 primary amine oxidase activity(GO:0008131)
2.8 24.9 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
2.7 16.4 GO:0016361 activin receptor activity, type I(GO:0016361)
2.7 10.9 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
2.7 16.3 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
2.7 16.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
2.7 8.0 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
2.6 7.9 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
2.6 39.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
2.5 10.1 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
2.4 12.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
2.3 27.9 GO:0070324 thyroid hormone binding(GO:0070324)
2.3 23.1 GO:0051959 dynein light intermediate chain binding(GO:0051959)
2.3 23.0 GO:0003680 AT DNA binding(GO:0003680)
2.3 11.5 GO:0050816 phosphothreonine binding(GO:0050816)
2.3 18.1 GO:0016421 CoA carboxylase activity(GO:0016421)
2.2 11.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
2.2 17.6 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021) vascular endothelial growth factor binding(GO:0038085)
2.1 10.5 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
2.1 6.2 GO:0004167 dopachrome isomerase activity(GO:0004167)
2.1 51.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
2.0 6.1 GO:0051425 PTB domain binding(GO:0051425)
2.0 27.8 GO:0033038 bitter taste receptor activity(GO:0033038)
2.0 27.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
1.9 43.9 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
1.9 22.9 GO:0003708 retinoic acid receptor activity(GO:0003708)
1.8 111.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
1.8 30.5 GO:0050811 GABA receptor binding(GO:0050811)
1.8 7.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
1.7 8.5 GO:0005550 pheromone binding(GO:0005550)
1.7 15.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
1.6 6.6 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
1.6 35.0 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
1.5 116.8 GO:0005518 collagen binding(GO:0005518)
1.5 19.6 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
1.5 4.5 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
1.5 31.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
1.5 5.9 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
1.4 44.8 GO:0051393 alpha-actinin binding(GO:0051393)
1.4 9.5 GO:0001849 complement component C1q binding(GO:0001849)
1.3 46.9 GO:0001540 beta-amyloid binding(GO:0001540)
1.3 9.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
1.3 5.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
1.3 6.4 GO:0032137 guanine/thymine mispair binding(GO:0032137)
1.3 19.1 GO:0005351 sugar:proton symporter activity(GO:0005351)
1.3 8.8 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
1.3 17.6 GO:0017166 vinculin binding(GO:0017166)
1.2 46.4 GO:0017080 sodium channel regulator activity(GO:0017080)
1.2 14.6 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
1.2 13.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
1.2 14.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
1.2 4.6 GO:0033149 FFAT motif binding(GO:0033149)
1.1 29.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
1.1 9.1 GO:0008430 selenium binding(GO:0008430)
1.1 8.0 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
1.1 37.0 GO:0050699 WW domain binding(GO:0050699)
1.1 29.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
1.1 3.2 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
1.1 64.4 GO:0005080 protein kinase C binding(GO:0005080)
1.0 28.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
1.0 31.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
1.0 3.0 GO:0061665 SUMO ligase activity(GO:0061665)
0.9 10.4 GO:0042301 phosphate ion binding(GO:0042301)
0.9 8.5 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.9 14.9 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.9 60.4 GO:0017022 myosin binding(GO:0017022)
0.9 17.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.9 26.1 GO:0017147 Wnt-protein binding(GO:0017147)
0.9 21.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.8 12.7 GO:0046527 glucosyltransferase activity(GO:0046527)
0.8 4.8 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.8 9.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.8 8.7 GO:0001848 complement binding(GO:0001848)
0.8 9.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.7 18.7 GO:0030371 translation repressor activity(GO:0030371)
0.7 2.9 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.7 11.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.7 3.3 GO:0001601 peptide YY receptor activity(GO:0001601)
0.6 6.5 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.6 26.4 GO:0030507 spectrin binding(GO:0030507)
0.6 3.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.6 12.6 GO:0070064 proline-rich region binding(GO:0070064)
0.6 205.7 GO:0003779 actin binding(GO:0003779)
0.6 8.3 GO:0035497 cAMP response element binding(GO:0035497)
0.5 6.6 GO:1990405 protein antigen binding(GO:1990405)
0.5 8.8 GO:0030275 LRR domain binding(GO:0030275)
0.5 4.3 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.5 2.1 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032) TFIIIC-class transcription factor binding(GO:0001156)
0.5 26.6 GO:0019003 GDP binding(GO:0019003)
0.5 17.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.5 11.9 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637)
0.5 3.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.5 10.0 GO:0005112 Notch binding(GO:0005112)
0.4 2.7 GO:0019767 IgE receptor activity(GO:0019767)
0.4 4.4 GO:0045499 chemorepellent activity(GO:0045499)
0.4 59.2 GO:0008237 metallopeptidase activity(GO:0008237)
0.4 9.5 GO:0070412 R-SMAD binding(GO:0070412)
0.4 2.4 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.4 6.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.4 5.5 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.4 2.4 GO:0048030 disaccharide binding(GO:0048030)
0.4 7.5 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.4 9.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.4 1.9 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.4 468.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.4 224.6 GO:0005509 calcium ion binding(GO:0005509)
0.4 3.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.3 6.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.3 1.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.3 7.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.3 4.4 GO:0071837 HMG box domain binding(GO:0071837)
0.3 1.0 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.2 7.0 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.2 0.7 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.2 3.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 11.1 GO:0043022 ribosome binding(GO:0043022)
0.2 32.0 GO:0061659 ubiquitin-like protein ligase activity(GO:0061659)
0.2 1.9 GO:0015266 protein channel activity(GO:0015266)
0.2 2.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.2 4.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.2 14.3 GO:0051219 phosphoprotein binding(GO:0051219)
0.2 11.7 GO:0060090 binding, bridging(GO:0060090)
0.2 14.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.2 0.8 GO:0015142 tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1 25.0 GO:0005244 voltage-gated ion channel activity(GO:0005244) voltage-gated channel activity(GO:0022832)
0.1 14.6 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 7.6 GO:0051117 ATPase binding(GO:0051117)
0.1 11.7 GO:0008565 protein transporter activity(GO:0008565)
0.1 6.3 GO:0016247 channel regulator activity(GO:0016247)
0.1 4.3 GO:0050661 NADP binding(GO:0050661)
0.1 30.7 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 3.3 GO:0005109 frizzled binding(GO:0005109)
0.1 1.3 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 5.0 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.1 0.8 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 0.8 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.5 GO:0098879 structural constituent of postsynaptic specialization(GO:0098879) structural constituent of synapse(GO:0098918) structural constituent of postsynaptic density(GO:0098919)
0.0 2.0 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 1.6 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 1.6 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 1.1 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.2 GO:0050431 transforming growth factor beta binding(GO:0050431)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
6.2 31.0 PID IL3 PATHWAY IL3-mediated signaling events
4.2 188.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
3.3 165.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
2.8 30.8 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
2.7 43.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
2.4 9.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
2.2 103.2 ST P38 MAPK PATHWAY p38 MAPK Pathway
2.1 39.3 PID AP1 PATHWAY AP-1 transcription factor network
1.8 306.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
1.7 33.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
1.5 20.6 PID ALK2 PATHWAY ALK2 signaling events
1.4 8.7 PID CD40 PATHWAY CD40/CD40L signaling
1.4 58.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
1.3 12.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
1.2 28.7 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
1.2 40.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
1.2 30.4 PID WNT SIGNALING PATHWAY Wnt signaling network
1.1 12.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
1.1 64.8 PID LKB1 PATHWAY LKB1 signaling events
1.0 11.5 PID MYC PATHWAY C-MYC pathway
1.0 15.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
1.0 34.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.9 16.0 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.9 130.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.9 37.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.9 30.2 PID RAS PATHWAY Regulation of Ras family activation
0.8 18.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.8 29.8 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.8 18.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.8 26.3 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.8 12.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.8 25.8 SIG CHEMOTAXIS Genes related to chemotaxis
0.8 42.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.7 14.7 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.7 7.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.7 9.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.7 14.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.7 13.7 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.6 30.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.6 11.1 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.6 2.4 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.6 131.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.5 16.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.5 42.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.5 19.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.4 3.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.4 12.8 PID BMP PATHWAY BMP receptor signaling
0.4 4.3 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.4 8.8 PID FGF PATHWAY FGF signaling pathway
0.3 8.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.3 5.8 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.2 9.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.2 7.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 10.0 PID NOTCH PATHWAY Notch signaling pathway
0.2 10.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.2 2.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.2 1.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.2 7.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 2.0 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 2.9 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
12.6 492.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
7.9 79.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
5.6 222.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
5.2 46.6 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
4.2 58.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
3.8 11.5 REACTOME XENOBIOTICS Genes involved in Xenobiotics
3.3 86.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
3.1 72.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
3.0 26.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
2.9 123.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
2.9 51.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
2.4 38.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
2.4 45.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
2.1 21.2 REACTOME AMYLOIDS Genes involved in Amyloids
1.8 24.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
1.8 85.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
1.8 40.0 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
1.7 20.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
1.6 28.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
1.6 29.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
1.5 32.9 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
1.5 23.6 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
1.4 70.5 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
1.3 39.3 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
1.2 24.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
1.0 10.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.9 11.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.9 13.0 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.9 8.7 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.8 9.1 REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES Genes involved in MAPK targets/ Nuclear events mediated by MAP kinases
0.7 12.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.7 6.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.7 48.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.7 15.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.7 8.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.6 8.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.6 12.9 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.6 12.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.6 19.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.6 7.0 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.5 29.4 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.5 4.7 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.5 14.3 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.5 13.0 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.5 88.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.5 27.4 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.5 22.8 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.5 7.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.5 3.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.4 10.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.4 8.8 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.4 8.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.4 12.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.3 13.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.3 11.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.3 6.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 14.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 8.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 2.5 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.2 5.6 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.2 11.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 3.5 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.1 8.1 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.0 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 3.9 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 3.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 0.8 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 2.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 9.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.5 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression