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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Nfe2l1_Mafg

Z-value: 0.89

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Transcription factors associated with Nfe2l1_Mafg

Gene Symbol Gene ID Gene Info
ENSRNOG00000008830 nuclear factor, erythroid 2-like 1
ENSRNOG00000036697 MAF bZIP transcription factor G

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfe2l1rn6_v1_chr10_-_84698886_846988860.342.9e-10Click!
Mafgrn6_v1_chr10_-_109811323_109811323-0.262.9e-06Click!

Activity profile of Nfe2l1_Mafg motif

Sorted Z-values of Nfe2l1_Mafg motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_70687500 32.98 ENSRNOT00000037432

chr9_-_115850634 32.82 ENSRNOT00000049720
leucine rich repeat containing 30
chr13_-_103080920 25.27 ENSRNOT00000034990

chr18_-_63825408 25.25 ENSRNOT00000043709
similar to glyceraldehyde-3-phosphate dehydrogenase
chr11_-_72109964 23.26 ENSRNOT00000058917

chr3_+_57770948 20.88 ENSRNOT00000038429

chr10_-_102289837 19.81 ENSRNOT00000044922

chr1_+_193537137 19.72 ENSRNOT00000029967

chr3_+_132052612 16.86 ENSRNOT00000030148

chr2_+_222792999 16.62 ENSRNOT00000036228

chr5_+_115649046 15.87 ENSRNOT00000041328
glyceraldehyde-3-phosphate dehydrogenase
chr13_+_56262190 15.63 ENSRNOT00000032908

chr3_-_46726946 15.54 ENSRNOT00000011030
ENSRNOT00000086576
integrin subunit beta 6
chr16_+_25773602 13.91 ENSRNOT00000047750
glyceraldehyde-3-phosphate dehydrogenase, pseudogene 2
chr16_+_16949232 12.68 ENSRNOT00000047499

chr8_+_100260049 9.58 ENSRNOT00000011090

chr8_-_36410612 9.14 ENSRNOT00000091308
FAD-dependent oxidoreductase domain containing 1
chr6_+_55085313 8.07 ENSRNOT00000005458

chrM_+_7006 8.00 ENSRNOT00000043693
mitochondrially encoded cytochrome c oxidase II
chr3_-_2453933 7.86 ENSRNOT00000014060
solute carrier family 34 member 3
chr1_+_229107911 7.18 ENSRNOT00000016484
olfactory receptor 338
chr6_-_108076186 7.13 ENSRNOT00000014814
family with sequence similarity 161, member B
chr1_+_106998623 6.70 ENSRNOT00000022383
solute carrier family 17 member 6
chr3_-_51054378 6.46 ENSRNOT00000089243
growth factor receptor bound protein 14
chr7_-_117259791 6.36 ENSRNOT00000086550
plectin
chr1_-_222350173 6.27 ENSRNOT00000030625
fibronectin leucine rich transmembrane protein 1
chr1_-_215536980 5.95 ENSRNOT00000027344
interferon induced transmembrane protein 10
chr10_-_59984862 5.90 ENSRNOT00000087700
olfactory receptor 1485
chr14_-_77222006 5.53 ENSRNOT00000007074
dopamine receptor D5
chr1_-_215536770 5.29 ENSRNOT00000078030
interferon induced transmembrane protein 10
chr10_-_78690857 5.23 ENSRNOT00000089255
similar to glyceraldehyde-3-phosphate dehydrogenase
chr8_+_36410683 5.10 ENSRNOT00000015177
SRP receptor alpha subunit
chr11_-_83483513 4.60 ENSRNOT00000084380

chr2_-_77784522 4.52 ENSRNOT00000030328
similar to RIKEN cDNA 0610040D20
chr4_-_161757447 4.48 ENSRNOT00000008737
FK506 binding protein 4
chr6_+_108076306 4.25 ENSRNOT00000014913
coenzyme Q6 monooxygenase
chr1_+_166991474 4.22 ENSRNOT00000027150
RhoA activator C11orf59-like
chr10_-_60542410 4.21 ENSRNOT00000082426
olfactory receptor 1498
chr10_-_60006037 4.13 ENSRNOT00000065541
olfactory receptor 1485
chr19_-_15840990 4.11 ENSRNOT00000015583
iroquois homeobox 3
chr1_-_22570303 3.59 ENSRNOT00000035539
trace amine-associated receptor 3
chr6_+_10912383 3.55 ENSRNOT00000061747
ENSRNOT00000086247
tetratricopeptide repeat domain 7A
chr3_-_78235760 3.32 ENSRNOT00000008435
olfactory receptor 698
chr8_+_43722228 3.15 ENSRNOT00000084016
olfactory receptor 1325
chr1_+_229877560 3.05 ENSRNOT00000089953
olfactory receptor 347
chr3_+_78748001 2.88 ENSRNOT00000008715
olfactory receptor 722
chr6_-_102353403 2.84 ENSRNOT00000090407
vesicle transport through interaction with t-SNAREs 1B
chr1_-_209641123 2.83 ENSRNOT00000021702
early B-cell factor 3
chr10_-_14848967 2.81 ENSRNOT00000080944
somatostatin receptor 5
chr5_+_154800226 2.78 ENSRNOT00000016046
5-hydroxytryptamine receptor 1D
chr8_-_43249887 2.73 ENSRNOT00000060094
olfactory receptor 1305
chr13_+_92249759 2.68 ENSRNOT00000089352
olfactory receptor 1596
chr9_+_74124016 2.67 ENSRNOT00000019023
carbamoyl-phosphate synthase 1
chr10_-_12571316 2.65 ENSRNOT00000074440
olfactory receptor 1372
chr8_-_43082948 2.63 ENSRNOT00000072050
olfactory receptor 8G5-like
chr9_-_86103158 2.48 ENSRNOT00000021528
cullin 3
chr1_-_61626454 2.43 ENSRNOT00000038190
vomeronasal 1 receptor 22
chr13_+_92504374 2.32 ENSRNOT00000033697
olfactory receptor 1602
chr3_-_76926151 2.31 ENSRNOT00000049517
olfactory receptor 641
chr5_-_58917822 2.31 ENSRNOT00000082554

chr10_+_36530719 2.28 ENSRNOT00000046476
olfactory receptor 1409
chr3_+_21313227 2.26 ENSRNOT00000036335
similar to olfactory receptor Olr1374
chr1_-_230766515 2.24 ENSRNOT00000040049
olfactory receptor 383
chr8_+_43763859 2.21 ENSRNOT00000080504
olfactory receptor 1328
chr6_+_28557633 2.18 ENSRNOT00000087058
general transcription factor IIH, polypeptide 5
chr3_+_73988945 2.14 ENSRNOT00000050404
olfactory receptor 515
chr17_+_11101306 2.10 ENSRNOT00000030893
dopamine receptor D1
chr17_-_81558565 2.10 ENSRNOT00000048715

chr15_-_29810811 2.09 ENSRNOT00000060386

chr1_+_230576298 2.05 ENSRNOT00000049799
olfactory receptor 374
chr1_+_70454322 1.95 ENSRNOT00000072272
olfactory receptor 4
chr3_+_110508403 1.90 ENSRNOT00000079959

chr10_-_88000423 1.90 ENSRNOT00000076787
ENSRNOT00000046751
ENSRNOT00000091394
keratin 32
chr3_-_73755510 1.83 ENSRNOT00000083628
olfactory receptor 502
chr19_+_28377249 1.79 ENSRNOT00000059668
vomeronasal 1 receptor 21
chr1_+_229480184 1.78 ENSRNOT00000044115
olfactory receptor 387
chr8_-_43235208 1.73 ENSRNOT00000060095
olfactory receptor 1304
chr2_+_62360754 1.63 ENSRNOT00000017276
golgi phosphoprotein 3
chr9_+_74960255 1.53 ENSRNOT00000077342

chr1_+_167748100 1.51 ENSRNOT00000024961
olfactory receptor 45
chr3_-_102773801 1.49 ENSRNOT00000047051
olfactory receptor 767
chr1_-_169973241 1.46 ENSRNOT00000023315
olfactory receptor pseudogene 191
chrX_+_133227660 1.42 ENSRNOT00000004591
actin-related protein T1
chr3_-_72818843 1.40 ENSRNOT00000041926
olfactory receptor 442
chr1_+_22319353 1.39 ENSRNOT00000038523
trace amine-associated receptor 9
chr16_-_54899347 1.36 ENSRNOT00000016321
VPS37A, ESCRT-I subunit
chr17_-_45688058 1.31 ENSRNOT00000086807
olfactory receptor 1662
chr15_-_28446785 1.30 ENSRNOT00000015439
olfactory receptor 1638
chr17_+_36771639 1.26 ENSRNOT00000015147
G protein-coupled receptor 50
chr1_+_169552487 1.17 ENSRNOT00000023119
olfactory receptor 152
chr10_-_12731897 1.15 ENSRNOT00000042582
olfactory receptor 1378
chr1_+_70480941 1.15 ENSRNOT00000072404
olfactory receptor 6
chr9_+_50966766 1.13 ENSRNOT00000076636
ERCC excision repair 5, endonuclease
chr3_+_16039249 1.10 ENSRNOT00000046196
olfactory receptor 403
chr7_-_81592206 1.07 ENSRNOT00000007979
angiopoietin 1
chr7_-_7311272 1.06 ENSRNOT00000040812
olfactory receptor 1020
chr1_+_171274305 1.04 ENSRNOT00000051038
olfactory receptor 234
chr1_+_230217215 1.02 ENSRNOT00000072772
similar to olfactory receptor 1467
chr8_+_43382176 1.01 ENSRNOT00000047759
olfactory receptor 1311
chr2_-_89498395 0.99 ENSRNOT00000068507

chr1_-_22559830 0.97 ENSRNOT00000047810
trace amine-associated receptor 4
chr7_+_5401508 0.88 ENSRNOT00000050898
olfactory receptor 903
chr1_+_230450529 0.86 ENSRNOT00000045383
olfactory receptor 371
chr15_+_27243268 0.74 ENSRNOT00000046583
olfactory receptor 1615
chr10_-_87248572 0.74 ENSRNOT00000066637
ENSRNOT00000085677
keratin 26
chr11_+_65610352 0.69 ENSRNOT00000065766
similar to Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)
chr1_+_212181374 0.60 ENSRNOT00000085921
adhesion G protein-coupled receptor A1
chr11_-_32469566 0.56 ENSRNOT00000002718
similar to RIKEN cDNA 4930563D23
chr5_-_137515690 0.53 ENSRNOT00000049593
olfactory receptor 2D2-like
chr4_+_72670543 0.52 ENSRNOT00000044838
olfactory receptor 821
chr16_+_54899452 0.39 ENSRNOT00000016882
CCR4-NOT transcription complex, subunit 7
chr10_-_47825252 0.31 ENSRNOT00000087102
epsin 2
chr9_+_95221474 0.25 ENSRNOT00000066839
UDP glucuronosyltransferase family 1 member A5
chr3_-_20853708 0.23 ENSRNOT00000010360
olfactory receptor 411
chrX_-_49530166 0.19 ENSRNOT00000072026
serine and arginine rich splicing factor 8
chr8_-_40564556 0.15 ENSRNOT00000075779
olfactory receptor 883
chr2_-_252451999 0.13 ENSRNOT00000021861
deoxyribonuclease 2 beta
chr3_+_114236718 0.13 ENSRNOT00000024201
dual oxidase maturation factor 2
chr1_+_230377079 0.12 ENSRNOT00000042937
olfactory receptor 367
chr17_-_45746753 0.05 ENSRNOT00000077475
similar to brain Zn-finger protein

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfe2l1_Mafg

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 15.9 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
3.1 15.5 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
1.8 5.5 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
1.3 6.5 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
1.1 7.9 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
1.0 4.1 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.8 4.2 GO:2000909 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.8 6.7 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.6 2.5 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.5 1.6 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
0.5 2.7 GO:0071400 cellular response to oleic acid(GO:0071400)
0.5 2.1 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.5 2.8 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.5 9.1 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.4 5.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.4 2.2 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.4 1.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.3 6.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.3 2.8 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.3 1.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.3 4.2 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 4.5 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.2 1.8 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.1 8.0 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 6.3 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 1.4 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 3.5 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.1 72.8 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 1.0 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.4 GO:0043928 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 7.8 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 0.2 GO:0052697 xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:2000609 regulation of thyroid hormone generation(GO:2000609)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 15.9 GO:0097452 GAIT complex(GO:0097452)
0.9 5.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.6 4.2 GO:0071986 Ragulator complex(GO:0071986)
0.5 8.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.4 2.5 GO:0005827 polar microtubule(GO:0005827)
0.4 6.4 GO:0030056 hemidesmosome(GO:0030056)
0.4 2.1 GO:0044326 dendritic spine neck(GO:0044326)
0.3 12.3 GO:0008305 integrin complex(GO:0008305)
0.3 6.7 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 2.2 GO:0000439 core TFIIH complex(GO:0000439)
0.2 1.1 GO:0005675 holo TFIIH complex(GO:0005675)
0.2 9.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 1.4 GO:0000813 ESCRT I complex(GO:0000813)
0.1 5.5 GO:0060170 ciliary membrane(GO:0060170)
0.1 2.8 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 4.5 GO:0044295 axonal growth cone(GO:0044295)
0.1 2.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 2.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 6.5 GO:0010008 endosome membrane(GO:0010008)
0.0 0.3 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.1 GO:0031526 brush border membrane(GO:0031526)
0.0 1.1 GO:0005902 microvillus(GO:0005902)
0.0 4.2 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 71.0 GO:0016021 integral component of membrane(GO:0016021)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 15.9 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
2.5 7.6 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
1.6 7.9 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.9 4.5 GO:0032767 copper-dependent protein binding(GO:0032767)
0.9 5.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.8 2.5 GO:0031208 POZ domain binding(GO:0031208)
0.5 2.8 GO:0004994 somatostatin receptor activity(GO:0004994)
0.4 6.7 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.3 5.9 GO:0001594 trace-amine receptor activity(GO:0001594)
0.3 8.0 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.3 1.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 6.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 2.8 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.2 2.7 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.2 6.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 2.2 GO:0000182 rDNA binding(GO:0000182)
0.2 4.2 GO:0071949 FAD binding(GO:0071949)
0.2 6.4 GO:0030506 ankyrin binding(GO:0030506)
0.2 1.1 GO:0000405 bubble DNA binding(GO:0000405)
0.1 5.2 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.1 12.3 GO:0005178 integrin binding(GO:0005178)
0.1 27.4 GO:0005549 odorant binding(GO:0005549)
0.1 1.6 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 4.2 GO:0032947 protein complex scaffold(GO:0032947)
0.1 45.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 4.2 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 15.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 7.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 2.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 2.5 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 7.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.2 6.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 15.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 6.2 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 1.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 14.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.1 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 2.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 2.7 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation