Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation
Downloads

Results for Nfatc3

Z-value: 0.68

Motif logo

Transcription factors associated with Nfatc3

Gene Symbol Gene ID Gene Info
ENSRNOG00000054264 nuclear factor of activated T-cells 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfatc3rn6_v1_chr19_+_38039564_38039564-0.036.4e-01Click!

Activity profile of Nfatc3 motif

Sorted Z-values of Nfatc3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_138483612 34.80 ENSRNOT00000085620
solute carrier family 38, member 4
chr2_-_182035032 26.91 ENSRNOT00000009813
fibrinogen beta chain
chr2_+_235264219 22.89 ENSRNOT00000086245
complement factor I
chr13_+_91080341 20.87 ENSRNOT00000000058
C-reactive protein
chr2_+_198655437 18.30 ENSRNOT00000028781
hemochromatosis type 2 (juvenile)
chr2_+_243502073 13.87 ENSRNOT00000015870
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr1_-_166037424 13.35 ENSRNOT00000026115
purinergic receptor P2Y2
chr16_-_7007051 13.12 ENSRNOT00000023984
inter-alpha trypsin inhibitor, heavy chain 3
chr16_-_7007287 12.90 ENSRNOT00000041216
inter-alpha trypsin inhibitor, heavy chain 3
chr9_+_14529218 11.69 ENSRNOT00000016893
apolipoprotein B mRNA editing enzyme catalytic subunit 2
chr2_-_105089659 11.18 ENSRNOT00000043381
carboxypeptidase B1
chr1_+_279798187 10.53 ENSRNOT00000024065
pancreatic lipase
chr10_-_41408518 9.83 ENSRNOT00000018967
neuromedin U receptor 2
chr12_+_24989298 9.64 ENSRNOT00000032780
elastin
chr17_-_35958077 9.43 ENSRNOT00000038532
angiotensin II receptor, type 1a
chr18_+_53915807 9.40 ENSRNOT00000026543
ADAM metallopeptidase with thrombospondin type 1 motif, 19
chr3_-_71845232 9.19 ENSRNOT00000078645
calcitonin receptor like receptor
chr1_+_151918571 9.04 ENSRNOT00000022342
cathepsin C
chr1_+_166433109 8.90 ENSRNOT00000026428
StAR-related lipid transfer domain containing 10
chr18_-_59819113 8.83 ENSRNOT00000065939
RGD1562699
chr1_+_189328246 8.45 ENSRNOT00000084260
acyl-CoA synthetase medium-chain family member 1
chr13_-_98478327 8.21 ENSRNOT00000030135
coenzyme Q8A
chr4_+_49056010 7.71 ENSRNOT00000038566
cadherin-like and PC-esterase domain containing 1
chr3_-_48535909 7.60 ENSRNOT00000008148
fibroblast activation protein, alpha
chr15_+_10120206 7.48 ENSRNOT00000033048
retinoic acid receptor, beta
chr18_-_77322690 7.33 ENSRNOT00000058382
nuclear factor of activated T-cells 1
chr15_-_14510828 7.18 ENSRNOT00000039347
sentan, cilia apical structure protein
chr19_-_1074333 7.07 ENSRNOT00000017983
ENSRNOT00000086995
cadherin 5
chr9_+_98924134 7.06 ENSRNOT00000027597
twist family bHLH transcription factor 2
chr16_+_10417185 6.99 ENSRNOT00000082186
annexin A8
chr11_+_7265828 6.88 ENSRNOT00000084765
1,4-alpha-glucan branching enzyme 1
chr20_-_49486550 6.63 ENSRNOT00000048270
ENSRNOT00000076541
PR/SET domain 1
chr3_-_110324084 6.63 ENSRNOT00000010381
Bcl2 modifying factor
chr20_+_26988774 6.58 ENSRNOT00000090083
myopalladin
chr8_-_114449956 6.57 ENSRNOT00000056414
collagen type VI alpha 6 chain
chr11_+_61609370 6.42 ENSRNOT00000088880
ENSRNOT00000082533
GRAM domain containing 1C
chr3_+_14482388 6.32 ENSRNOT00000025857
gelsolin
chr3_-_48536235 6.17 ENSRNOT00000083536
fibroblast activation protein, alpha
chr16_+_59077574 6.12 ENSRNOT00000090477
DLC1 Rho GTPase activating protein
chr11_-_38274217 6.02 ENSRNOT00000002206
receptor-interacting serine-threonine kinase 4
chr6_+_2216623 5.88 ENSRNOT00000008045
regulator of microtubule dynamics 2
chr12_-_41307285 5.87 ENSRNOT00000075317
ENSRNOT00000048782
ENSRNOT00000075234
2-5 oligoadenylate synthetase 1B
chr11_-_60679555 5.84 ENSRNOT00000059735
coiled-coil domain containing 80
chr2_-_197814808 5.82 ENSRNOT00000074156
ADAMTS-like 4
chr9_-_100306829 5.78 ENSRNOT00000038563
similar to hypothetical protein FLJ22671
chr8_-_18508971 5.75 ENSRNOT00000061339
mucin 16, cell surface associated
chr13_+_91481461 5.60 ENSRNOT00000012103
olfactory receptor 1576
chr17_-_81187739 5.34 ENSRNOT00000063911
3-hydroxyacyl-CoA dehydratase 1
chr10_-_32471454 5.27 ENSRNOT00000003224
sarcoglycan, delta
chr4_-_176922424 5.01 ENSRNOT00000055540
ATP binding cassette subfamily C member 9
chr16_-_47537476 4.94 ENSRNOT00000050279
claudin 24
chr17_-_51912496 4.77 ENSRNOT00000019272
inhibin beta A subunit
chr13_+_89586283 4.63 ENSRNOT00000079355
ENSRNOT00000049873
nuclear receptor subfamily 1, group I, member 3
chr2_+_195617021 4.47 ENSRNOT00000067042
ENSRNOT00000036656
RAR-related orphan receptor C
leucine rich repeat and Ig domain containing 4
chr10_+_83655460 4.43 ENSRNOT00000008011
G protein subunit gamma transducin 2
chr9_+_95221474 4.20 ENSRNOT00000066839
UDP glucuronosyltransferase family 1 member A5
chr14_-_72025137 4.19 ENSRNOT00000080604
C1q and tumor necrosis factor related protein 7
chr16_-_31301880 4.18 ENSRNOT00000084847
ENSRNOT00000083943

chr5_+_173256834 4.12 ENSRNOT00000089936
cyclin L2
chr10_-_74769637 4.10 ENSRNOT00000008889
zinc finger protein OZF-like
chr5_-_164747083 4.09 ENSRNOT00000010433
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr10_+_90930010 4.08 ENSRNOT00000003765
HIG1 hypoxia inducible domain family, member 1B
chr4_+_180291389 4.07 ENSRNOT00000002465
sarcospan
chr11_-_62128044 4.06 ENSRNOT00000093141
zinc finger and BTB domain containing 20
chr5_+_152533349 4.00 ENSRNOT00000067524
tripartite motif containing 63
chr1_+_177569618 3.95 ENSRNOT00000090042
TEA domain transcription factor 1
chr2_-_251532312 3.86 ENSRNOT00000019501
cysteine-rich, angiogenic inducer, 61
chr14_-_18591394 3.83 ENSRNOT00000003716
epiregulin
chr6_+_64649194 3.78 ENSRNOT00000039776

chr7_-_36499784 3.77 ENSRNOT00000011948
suppressor of cytokine signaling 2
chr12_-_51341663 3.67 ENSRNOT00000066892
ENSRNOT00000052202
phosphatidylinositol transfer protein, beta
chr5_+_173256637 3.49 ENSRNOT00000025531
cyclin L2
chr14_-_112946204 3.46 ENSRNOT00000056813
coiled-coil domain-containing protein 85A-like
chr1_+_163398891 3.40 ENSRNOT00000020513
guanylate cyclase 2E
chr10_-_103687425 3.36 ENSRNOT00000039284
Cd300 molecule-like family member F
chr7_-_117267402 3.32 ENSRNOT00000088945
plectin
chr1_+_171797516 3.31 ENSRNOT00000088110
PPFIA binding protein 2
chr15_-_34469350 3.24 ENSRNOT00000067536
adenylate cyclase 4
chr14_+_7618022 3.24 ENSRNOT00000088508
ENSRNOT00000002819
solute carrier family 10 member 6
chr1_+_41192824 3.24 ENSRNOT00000082133
estrogen receptor 1
chr7_-_117267803 3.23 ENSRNOT00000082271
plectin
chr14_+_5928737 3.21 ENSRNOT00000071877
ENSRNOT00000040985
ENSRNOT00000074889
macrophage activation 2 like
chr15_+_32763067 3.21 ENSRNOT00000011998

chr11_-_65845418 3.05 ENSRNOT00000091057
follistatin-like 1
chr12_-_30083824 3.01 ENSRNOT00000084968
tyrosylprotein sulfotransferase 1
chr12_+_13102019 2.95 ENSRNOT00000092628
ras-related C3 botulinum toxin substrate 1
chr4_+_99399148 2.94 ENSRNOT00000088018
ring finger protein 103
chr4_+_22084954 2.91 ENSRNOT00000090968
carnitine O-octanoyltransferase
chr3_-_151486693 2.89 ENSRNOT00000073736
ENSRNOT00000071099
growth differentiation factor 5
chr17_-_22143324 2.73 ENSRNOT00000019361
endothelin 1
chr2_-_45077219 2.71 ENSRNOT00000014319
granzyme K
chr1_-_266914093 2.64 ENSRNOT00000027526
calcium homeostasis modulator 2
chr4_-_2381271 2.48 ENSRNOT00000072287
motor neuron and pancreas homeobox 1
chr3_+_73390268 2.46 ENSRNOT00000052240
olfactory receptor 475
chr3_-_69637377 2.38 ENSRNOT00000074765

chr18_+_76770012 2.37 ENSRNOT00000089389
PQ loop repeat containing 1
chr16_+_54332660 2.37 ENSRNOT00000037685
microtubule associated tumor suppressor 1
chr7_-_132343169 2.36 ENSRNOT00000021064
ATP binding cassette subfamily D member 2
chr6_+_135890931 2.36 ENSRNOT00000042973
TNF alpha induced protein 2
chr11_+_84094520 2.33 ENSRNOT00000046642
ribosomal protein S15A-like 2
chr2_-_174413038 2.30 ENSRNOT00000089229
ENSRNOT00000037115
golgi integral membrane protein 4
chr7_-_54778848 2.28 ENSRNOT00000005399
GLI pathogenesis-related 1
chr13_-_83202864 2.27 ENSRNOT00000003976
X-C motif chemokine ligand 1
chr15_-_34444244 2.24 ENSRNOT00000027612
cell death-inducing DFFA-like effector b
chr7_-_29701586 2.23 ENSRNOT00000009084
ENSRNOT00000089269
anoctamin 4
chr9_-_78693028 2.20 ENSRNOT00000036359
ATP binding cassette subfamily A member 12
chr3_+_113251778 2.19 ENSRNOT00000083005
microtubule-associated protein 1A
chr16_-_6404578 2.12 ENSRNOT00000051371
calcium voltage-gated channel subunit alpha1 D
chr16_-_47535358 2.06 ENSRNOT00000040731
claudin 22
chr1_+_37507276 2.05 ENSRNOT00000047627
adenylate cyclase 2
chr6_+_95816749 2.02 ENSRNOT00000008880
SIX homeobox 6
chrX_-_100207974 1.99 ENSRNOT00000091859

chr1_+_164706276 1.94 ENSRNOT00000024311
olfactory receptor 36
chr7_+_27438351 1.94 ENSRNOT00000077976

chr2_+_212435728 1.89 ENSRNOT00000046960

chrX_+_83678339 1.85 ENSRNOT00000005997
apolipoprotein O-like
chr8_+_42322813 1.75 ENSRNOT00000040431
olfactory receptor 1241
chr10_-_87891285 1.73 ENSRNOT00000090052

chr6_-_128894761 1.70 ENSRNOT00000029346
T-cell leukemia/lymphoma 1A
chr5_+_107233230 1.68 ENSRNOT00000029976
interferon, epsilon
chr6_+_137063611 1.65 ENSRNOT00000017504
hypothetical protein LOC691485
chr10_+_3655038 1.65 ENSRNOT00000045047
calcineurin-like phosphoesterase domain containing 1
chr6_-_1454480 1.64 ENSRNOT00000072810
eukaryotic translation initiation factor 2-alpha kinase 2
chr8_+_20780898 1.64 ENSRNOT00000052197
similar to olfactory receptor Olr1185
chr13_+_107580629 1.63 ENSRNOT00000003557
transmembrane protein 14C
chr1_+_230160365 1.62 ENSRNOT00000088190
olfactory receptor 361
chr3_-_176958880 1.60 ENSRNOT00000078661
zinc finger and BTB domain containing 46
chr8_+_116776494 1.59 ENSRNOT00000050702
cadherin-related family member 4
chr1_-_149778698 1.59 ENSRNOT00000089920
olfactory receptor 6F1-like
chr3_-_93216495 1.59 ENSRNOT00000010580
ets homologous factor
chr3_+_67849966 1.58 ENSRNOT00000057826
dual specificity phosphatase 19
chr12_-_51965779 1.58 ENSRNOT00000056733
replication protein A3-like
chr5_-_58078545 1.55 ENSRNOT00000075777
ciliary neurotrophic factor receptor
chr2_-_199563386 1.55 ENSRNOT00000075261

chr13_+_90116843 1.54 ENSRNOT00000006306
Cd48 molecule
chr4_-_165774126 1.51 ENSRNOT00000007453
taste receptor, type 2, member 107
chr2_-_198458041 1.50 ENSRNOT00000082450
Fc fragment of IgG receptor Ia
chr17_-_27665266 1.49 ENSRNOT00000060218
ras responsive element binding protein 1
chr4_-_56114254 1.49 ENSRNOT00000010673
leucine rich repeat containing 4
chr3_-_112061796 1.47 ENSRNOT00000056258
phospholipase A2 group IVD
chr1_-_230649938 1.46 ENSRNOT00000017615
olfactory receptor 377
chr8_+_61603991 1.45 ENSRNOT00000065156

chr16_-_10603850 1.42 ENSRNOT00000087737
family with sequence similarity 35, member A
chr1_-_2017488 1.39 ENSRNOT00000021905
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr3_+_114087287 1.39 ENSRNOT00000023017
beta-2 microglobulin
chr1_+_16910069 1.37 ENSRNOT00000020015
aldehyde dehydrogenase 8 family, member A1
chr2_-_35229353 1.37 ENSRNOT00000085814
olfactory receptor 146-like
chr3_-_103066392 1.37 ENSRNOT00000044181
olfactory receptor 776
chr10_+_85257876 1.36 ENSRNOT00000014752
mitochondrial ribosomal protein L45
chr5_+_152466331 1.34 ENSRNOT00000082841
uncharacterized LOC108351043
chr7_+_6215743 1.34 ENSRNOT00000050967
olfactory receptor 1002
chr3_-_46942966 1.31 ENSRNOT00000087439
RNA binding motif, single stranded interacting protein 1
chr2_+_206902962 1.29 ENSRNOT00000040909
similar to Acidic ribosomal phosphoprotein P0
chr15_-_31770690 1.24 ENSRNOT00000082666

chr1_+_229889771 1.16 ENSRNOT00000085941
olfactory receptor 348
chr1_+_267359830 1.15 ENSRNOT00000015495
STE20-like kinase
chr3_-_76279104 1.14 ENSRNOT00000007796
olfactory receptor 608
chr3_+_21016266 1.13 ENSRNOT00000010473
olfactory receptor 420
chr3_+_61597382 1.12 ENSRNOT00000068636
homeo box D12
chr1_+_196095214 1.11 ENSRNOT00000080741
similar to ribosomal protein S15a
chrX_-_115073890 1.09 ENSRNOT00000006638
calpain 6
chr12_+_4310334 1.09 ENSRNOT00000041244
vomeronasal 2 receptor, 60
chr13_-_89606326 1.08 ENSRNOT00000029179
Fc fragment of IgE receptor Ig
chr14_-_44225713 1.08 ENSRNOT00000049161
similar to ribosomal protein L14
chr2_+_188583664 1.08 ENSRNOT00000045477
dolichyl-phosphate mannosyltransferase subunit 3
chr4_+_99168248 1.07 ENSRNOT00000058186
uncharacterized LOC102552663
chr3_-_47025128 1.07 ENSRNOT00000011682
RNA binding motif, single stranded interacting protein 1
chr4_-_71080499 1.04 ENSRNOT00000074623
similar to odorant receptor ORZ6
chrX_-_137015266 1.03 ENSRNOT00000040369
olfactory receptor 1767
chr17_+_60287203 1.02 ENSRNOT00000025585
armadillo repeat containing 4
chr5_-_147784311 1.01 ENSRNOT00000074172
family with sequence similarity 167, member B
chr4_+_96562725 1.00 ENSRNOT00000009094
neuron-derived neurotrophic factor
chr5_-_9429859 0.97 ENSRNOT00000009462
alcohol dehydrogenase, iron containing, 1
chr3_-_74815509 0.97 ENSRNOT00000045173
olfactory receptor 499
chr6_+_69971227 0.97 ENSRNOT00000075349
forkhead box G1
chr1_+_229755649 0.95 ENSRNOT00000046384
olfactory receptor 340
chr4_-_125808281 0.94 ENSRNOT00000037848
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr1_-_172932507 0.94 ENSRNOT00000048478
similar to olfactory receptor Olr271
chr12_+_3969493 0.93 ENSRNOT00000042692
vomeronasal 2 receptor, 59
chr17_-_81558565 0.92 ENSRNOT00000048715

chr11_-_45688560 0.92 ENSRNOT00000081508
olfactory receptor 1536
chr1_+_213583606 0.92 ENSRNOT00000088899

chr2_+_150106292 0.90 ENSRNOT00000073078
arylacetamide deacetylase-like 2-like
chr1_+_174702373 0.89 ENSRNOT00000013733
zinc finger protein 143
chr13_+_27238767 0.88 ENSRNOT00000003495
serpin family B member 11
chr8_-_43304560 0.87 ENSRNOT00000060092
olfactory receptor 1307
chr1_-_230115342 0.87 ENSRNOT00000017444
olfactory receptor 360
chr2_-_250600517 0.86 ENSRNOT00000016872
heparan sulfate 2-O-sulfotransferase 1
chr1_-_6970040 0.85 ENSRNOT00000016273
utrophin
chr7_-_16432738 0.83 ENSRNOT00000049493
olfactory receptor 932
chr13_+_56513286 0.81 ENSRNOT00000015596
zinc finger and BTB domain containing 41
chr10_+_46511271 0.81 ENSRNOT00000080828
retinoic acid induced 1
chrX_-_138148967 0.81 ENSRNOT00000033968
FERM domain containing 7
chr3_-_105298108 0.78 ENSRNOT00000010994
Rho GTPase activating protein 11A
chr1_+_129255396 0.78 ENSRNOT00000040147
family with sequence similarity 169, member B
chr1_-_147272006 0.77 ENSRNOT00000086862

chr15_+_105640097 0.75 ENSRNOT00000014300
muscleblind-like splicing regulator 2
chrX_-_105568343 0.74 ENSRNOT00000029807
armadillo repeat containing, X-linked 6
chr13_-_91638661 0.74 ENSRNOT00000045429
olfactory receptor 1579
chr1_-_6903486 0.73 ENSRNOT00000086574
utrophin

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfatc3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.4 19.3 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
5.4 26.9 GO:0043152 induction of bacterial agglutination(GO:0043152)
4.6 13.8 GO:0097325 melanocyte proliferation(GO:0097325)
3.5 20.9 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
3.1 9.4 GO:0071298 cellular response to L-ascorbic acid(GO:0071298)
2.9 11.7 GO:0016554 cytidine to uridine editing(GO:0016554)
2.3 13.9 GO:0006069 ethanol oxidation(GO:0006069)
2.1 6.3 GO:1903903 protein processing in phagocytic vesicle(GO:1900756) regulation of establishment of T cell polarity(GO:1903903) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
1.8 7.3 GO:0002337 B-1a B cell differentiation(GO:0002337)
1.8 5.3 GO:0071529 cementum mineralization(GO:0071529)
1.7 7.0 GO:0032429 regulation of phospholipase A2 activity(GO:0032429)
1.5 13.4 GO:0071415 cellular response to purine-containing compound(GO:0071415)
1.4 4.1 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
1.3 8.9 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
1.2 4.8 GO:0060279 positive regulation of ovulation(GO:0060279)
1.2 7.1 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
1.1 18.3 GO:0016540 protein autoprocessing(GO:0016540)
1.1 2.3 GO:0035711 T-helper 1 cell activation(GO:0035711)
1.1 3.4 GO:2000426 regulation of interleukin-4-mediated signaling pathway(GO:1902214) negative regulation of apoptotic cell clearance(GO:2000426)
1.0 3.0 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
1.0 5.0 GO:0060327 cytoplasmic actin-based contraction involved in cell motility(GO:0060327)
1.0 4.0 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
1.0 5.8 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
1.0 10.5 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.9 7.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.9 2.7 GO:0031583 phospholipase D-activating G-protein coupled receptor signaling pathway(GO:0031583)
0.9 4.5 GO:0072615 interleukin-17 secretion(GO:0072615)
0.9 2.6 GO:0002892 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) positive regulation of type IIa hypersensitivity(GO:0001798) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892) positive regulation of type II hypersensitivity(GO:0002894)
0.8 6.8 GO:0060591 chondroblast differentiation(GO:0060591)
0.8 6.6 GO:0051136 regulation of NK T cell differentiation(GO:0051136)
0.8 26.0 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.8 3.2 GO:1990375 baculum development(GO:1990375)
0.8 7.1 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.7 22.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.7 9.2 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.6 7.6 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.6 6.6 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.6 3.0 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.6 2.9 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.6 6.6 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.5 3.8 GO:0045410 oogenesis stage(GO:0022605) positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.5 8.2 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.5 4.2 GO:0052697 xenobiotic glucuronidation(GO:0052697)
0.5 1.4 GO:0002481 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481)
0.4 2.2 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.4 2.2 GO:0035627 ceramide transport(GO:0035627)
0.4 1.6 GO:0045650 negative regulation of macrophage differentiation(GO:0045650) negative regulation of dendritic cell differentiation(GO:2001199)
0.4 1.5 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.4 6.1 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.4 4.0 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.3 6.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.3 2.4 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.3 1.6 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.3 25.5 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.3 0.9 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 0.7 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.2 9.0 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.2 2.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.2 0.7 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.2 0.6 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2 2.5 GO:0060539 diaphragm development(GO:0060539)
0.2 1.6 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.2 0.6 GO:0071461 cellular response to redox state(GO:0071461)
0.2 1.4 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 8.7 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.2 2.4 GO:0051601 exocyst localization(GO:0051601)
0.2 0.7 GO:0046013 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.2 0.5 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.7 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 1.9 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 4.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 6.9 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 0.7 GO:0002159 desmosome assembly(GO:0002159)
0.1 1.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 1.6 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 1.0 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 1.9 GO:0042407 cristae formation(GO:0042407)
0.1 1.2 GO:0033129 positive regulation of histone phosphorylation(GO:0033129)
0.1 2.2 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 0.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.6 GO:0002399 MHC class II protein complex assembly(GO:0002399) peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.1 0.3 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.1 8.5 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 9.4 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 2.4 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 1.0 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.1 0.2 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.1 1.1 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 3.7 GO:0015914 phospholipid transport(GO:0015914)
0.1 5.8 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 1.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.8 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 0.6 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.8 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 2.2 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 1.5 GO:0009395 phospholipid catabolic process(GO:0009395)
0.0 0.6 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 1.8 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 5.9 GO:0051607 defense response to virus(GO:0051607)
0.0 2.9 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.1 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 1.5 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 5.8 GO:0030198 extracellular matrix organization(GO:0030198)
0.0 0.3 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.5 GO:0006828 manganese ion transport(GO:0006828)
0.0 5.2 GO:0048738 cardiac muscle tissue development(GO:0048738)
0.0 31.8 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 1.5 GO:0045576 mast cell activation(GO:0045576)
0.0 0.7 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 1.1 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.6 GO:0006379 mRNA cleavage(GO:0006379)
0.0 1.6 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.6 GO:0031103 axon regeneration(GO:0031103)
0.0 0.6 GO:0048661 positive regulation of smooth muscle cell proliferation(GO:0048661)
0.0 1.4 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.1 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.4 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0 3.2 GO:0015711 organic anion transport(GO:0015711)
0.0 0.0 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 26.9 GO:0005577 fibrinogen complex(GO:0005577)
3.3 19.7 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
2.4 9.6 GO:0071953 elastic fiber(GO:0071953)
2.0 13.8 GO:0071438 invadopodium membrane(GO:0071438)
1.6 4.8 GO:0043511 inhibin complex(GO:0043511)
1.3 4.0 GO:0071148 TEAD-1-YAP complex(GO:0071148)
1.3 5.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
1.1 6.3 GO:0030478 actin cap(GO:0030478)
0.9 5.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.7 8.9 GO:0046581 intercellular canaliculus(GO:0046581)
0.7 9.4 GO:0031983 vesicle lumen(GO:0031983)
0.6 11.7 GO:0005614 interstitial matrix(GO:0005614)
0.5 1.6 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.5 2.7 GO:0048237 Weibel-Palade body(GO:0033093) rough endoplasmic reticulum lumen(GO:0048237)
0.4 5.6 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.4 2.2 GO:0097209 epidermal lamellar body(GO:0097209)
0.4 1.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.3 8.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.3 6.6 GO:0030056 hemidesmosome(GO:0030056)
0.3 1.9 GO:0061617 MICOS complex(GO:0061617)
0.2 3.0 GO:0060091 kinocilium(GO:0060091)
0.2 0.7 GO:0042585 germinal vesicle(GO:0042585) dendritic branch(GO:0044307)
0.2 2.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 20.3 GO:0030175 filopodium(GO:0030175)
0.2 7.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 17.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 3.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 4.1 GO:0005581 collagen trimer(GO:0005581)
0.1 0.6 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 5.2 GO:0016459 myosin complex(GO:0016459)
0.1 7.5 GO:0031902 late endosome membrane(GO:0031902)
0.1 1.7 GO:0045120 pronucleus(GO:0045120)
0.1 2.4 GO:0000145 exocyst(GO:0000145)
0.1 6.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.6 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.2 GO:0070421 DNA ligase III-XRCC1 complex(GO:0070421)
0.1 0.3 GO:0035339 SPOTS complex(GO:0035339)
0.1 2.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 8.2 GO:0005923 bicellular tight junction(GO:0005923)
0.1 0.7 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 24.3 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 0.6 GO:0031932 TORC2 complex(GO:0031932)
0.0 57.9 GO:0005615 extracellular space(GO:0005615)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 2.4 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.0 GO:0097546 ciliary base(GO:0097546)
0.0 2.2 GO:0005811 lipid particle(GO:0005811)
0.0 2.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 9.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 1.4 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 2.0 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.0 GO:0000922 spindle pole(GO:0000922)
0.0 1.1 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.0 GO:0090543 Flemming body(GO:0090543)
0.0 0.5 GO:0005801 cis-Golgi network(GO:0005801)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 13.4 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
3.2 9.6 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
3.1 9.4 GO:0031711 bradykinin receptor binding(GO:0031711)
3.1 9.2 GO:0001605 adrenomedullin receptor activity(GO:0001605)
3.0 18.3 GO:0098821 BMP receptor activity(GO:0098821)
3.0 20.9 GO:0001849 complement component C1q binding(GO:0001849)
2.8 13.9 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
2.3 6.9 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
1.9 11.7 GO:0004126 cytidine deaminase activity(GO:0004126)
1.8 7.3 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
1.8 5.3 GO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
1.7 5.0 GO:0008281 sulfonylurea receptor activity(GO:0008281)
1.6 6.3 GO:0045159 myosin II binding(GO:0045159)
1.5 4.5 GO:0008142 oxysterol binding(GO:0008142)
1.4 13.8 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
1.4 4.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
1.3 9.0 GO:0031404 chloride ion binding(GO:0031404)
1.2 4.8 GO:0070699 type II activin receptor binding(GO:0070699)
1.1 8.5 GO:0003996 acyl-CoA ligase activity(GO:0003996)
1.0 3.0 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
1.0 2.9 GO:0016414 carnitine O-octanoyltransferase activity(GO:0008458) O-octanoyltransferase activity(GO:0016414)
0.9 2.7 GO:0031708 endothelin B receptor binding(GO:0031708)
0.8 3.4 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.7 5.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.6 3.2 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.6 7.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.6 3.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.6 12.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.5 1.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.5 10.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.4 22.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.4 3.0 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.4 4.6 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.4 11.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.4 6.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.4 7.7 GO:0017166 vinculin binding(GO:0017166)
0.4 1.6 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.4 2.2 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.4 2.9 GO:0036122 BMP binding(GO:0036122)
0.4 1.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.4 2.1 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.3 8.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.3 4.0 GO:0031432 titin binding(GO:0031432)
0.3 1.5 GO:0019770 IgG receptor activity(GO:0019770)
0.3 26.9 GO:0051087 chaperone binding(GO:0051087)
0.3 1.6 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.3 1.1 GO:0019767 IgE receptor activity(GO:0019767)
0.3 6.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 6.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 4.0 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 7.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.2 25.5 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.2 26.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 6.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 6.3 GO:0099589 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.2 5.8 GO:0001968 fibronectin binding(GO:0001968)
0.2 3.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 8.2 GO:0043531 ADP binding(GO:0043531)
0.2 1.4 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 1.0 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 4.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.7 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 15.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.6 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 1.5 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 1.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 7.1 GO:0008013 beta-catenin binding(GO:0008013)
0.1 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 3.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 2.3 GO:0008009 chemokine activity(GO:0008009)
0.1 0.9 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.1 1.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.8 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 1.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 2.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.9 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.6 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 1.5 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.6 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 2.2 GO:0005518 collagen binding(GO:0005518)
0.0 4.0 GO:0008201 heparin binding(GO:0008201)
0.0 3.2 GO:0008514 organic anion transmembrane transporter activity(GO:0008514)
0.0 12.7 GO:0005549 odorant binding(GO:0005549)
0.0 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.5 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.2 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 3.7 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.0 1.2 GO:0003823 antigen binding(GO:0003823)
0.0 1.1 GO:0035326 enhancer binding(GO:0035326)
0.0 1.4 GO:0001948 glycoprotein binding(GO:0001948)
0.0 0.7 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 12.7 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 2.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.0 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 30.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.4 23.8 PID IL6 7 PATHWAY IL6-mediated signaling events
0.4 19.3 PID BMP PATHWAY BMP receptor signaling
0.3 7.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.3 6.3 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.3 5.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.2 8.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 55.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 7.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.2 4.8 PID ALK1 PATHWAY ALK1 signaling events
0.2 3.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 4.4 PID CONE PATHWAY Visual signal transduction: Cones
0.1 0.7 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 6.6 NABA COLLAGENS Genes encoding collagen proteins
0.1 2.7 PID ENDOTHELIN PATHWAY Endothelins
0.1 3.2 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 3.1 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 10.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 7.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 1.6 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 3.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 7.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.9 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.0 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 20.9 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
1.8 22.9 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
1.7 13.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
1.7 26.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
1.0 12.0 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.9 33.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.5 4.8 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.5 1.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.4 6.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.4 21.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.4 5.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.3 10.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3 6.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.3 10.5 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.3 7.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 3.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 4.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 7.8 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 3.8 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 4.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 8.5 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 2.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 9.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.4 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 3.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 9.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 9.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 1.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 6.9 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.1 0.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 4.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 10.2 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.1 1.1 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 0.3 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1 2.1 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 3.7 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.7 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 4.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.0 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 2.0 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 4.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.2 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)