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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Nfatc2

Z-value: 2.04

Motif logo

Transcription factors associated with Nfatc2

Gene Symbol Gene ID Gene Info
ENSRNOG00000012175 nuclear factor of activated T-cells 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfatc2rn6_v1_chr3_-_165360292_165360292-0.123.4e-02Click!

Activity profile of Nfatc2 motif

Sorted Z-values of Nfatc2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_82533689 80.58 ENSRNOT00000014124
tropomodulin 2
chrX_+_6791136 63.06 ENSRNOT00000003984
norrin-like
chr2_+_58448917 51.66 ENSRNOT00000082562
RAN binding protein 3-like
chr17_-_81187739 46.59 ENSRNOT00000063911
3-hydroxyacyl-CoA dehydratase 1
chr5_+_64294321 46.32 ENSRNOT00000083796
Myb/SANT DNA binding domain containing 3
chr4_-_29778039 46.30 ENSRNOT00000074177
sarcoglycan, epsilon
chrX_+_107323215 45.94 ENSRNOT00000071874
transcription elongation factor A like 3
chr2_-_102370757 44.65 ENSRNOT00000074255
transcription elongation factor A (SII)-like 6
chr9_-_32019205 44.32 ENSRNOT00000016194
adhesion G protein-coupled receptor B3
chr3_-_48535909 43.64 ENSRNOT00000008148
fibroblast activation protein, alpha
chr11_+_36555416 43.49 ENSRNOT00000064981
SH3 domain binding glutamate-rich protein
chr9_-_61810417 42.96 ENSRNOT00000020910
raftlin family member 2
chr1_+_37507276 41.59 ENSRNOT00000047627
adenylate cyclase 2
chrX_-_106747303 41.15 ENSRNOT00000073529
transcription elongation factor A like 5
chr18_+_30023828 37.44 ENSRNOT00000079008
protocadherin alpha 4
chr18_+_29993361 35.49 ENSRNOT00000075810
protocadherin alpha 4
chr15_+_50891127 34.91 ENSRNOT00000020728
stanniocalcin 1
chr2_+_60920257 34.06 ENSRNOT00000025170
C1q and tumor necrosis factor related protein 3
chr8_-_105462141 33.95 ENSRNOT00000066731
ENSRNOT00000078760
calsyntenin 2
chr13_+_113691932 33.60 ENSRNOT00000084709
CD34 molecule
chr11_-_39448503 32.07 ENSRNOT00000047347
SH3 domain-binding glutamic acid-rich protein-like
chr14_-_112946204 31.99 ENSRNOT00000056813
coiled-coil domain-containing protein 85A-like
chr2_-_247446882 31.74 ENSRNOT00000021963
bone morphogenetic protein receptor type 1B
chr18_+_29987206 31.71 ENSRNOT00000027383
protocadherin alpha 4
chr2_-_44907030 30.44 ENSRNOT00000013979
glutathione peroxidase 8
chr11_+_75905443 30.39 ENSRNOT00000002650
fibroblast growth factor 12
chr8_+_44847157 30.14 ENSRNOT00000080288
CXADR-like membrane protein
chr2_-_62634785 30.11 ENSRNOT00000017937
PDZ domain containing 2
chr12_-_12712742 29.62 ENSRNOT00000034483
radial spoke head 10 homolog B
chr7_-_29701586 29.24 ENSRNOT00000009084
ENSRNOT00000089269
anoctamin 4
chr3_+_122836446 29.09 ENSRNOT00000028816
early B-cell factor 4
chr4_-_16130848 29.01 ENSRNOT00000042914
calcium voltage-gated channel auxiliary subunit alpha2delta 1
chr3_-_48536235 29.00 ENSRNOT00000083536
fibroblast activation protein, alpha
chr5_+_59228199 28.89 ENSRNOT00000060282
histidine rich carboxyl terminus 1
chr3_-_176666282 28.49 ENSRNOT00000016947
eukaryotic translation elongation factor 1 alpha 2
chr4_-_16130563 28.42 ENSRNOT00000090240
ENSRNOT00000034969
calcium voltage-gated channel auxiliary subunit alpha2delta 1
chrX_-_40086870 28.35 ENSRNOT00000010027
small muscle protein, X-linked
chr18_+_29966245 28.34 ENSRNOT00000074028
protocadherin alpha 4
chr7_+_139685573 27.74 ENSRNOT00000088376
phosphofructokinase, muscle
chr18_+_30496318 27.32 ENSRNOT00000027179
protocadherin beta 11
chr9_+_84569597 27.15 ENSRNOT00000020161
acyl-CoA synthetase long-chain family member 3
chr18_+_29999290 27.12 ENSRNOT00000027372
protocadherin alpha 4
chr3_-_107760550 27.09 ENSRNOT00000077091
ENSRNOT00000051638
Meis homeobox 2
chr2_+_266315036 27.00 ENSRNOT00000055245
wntless Wnt ligand secretion mediator
chr6_+_98284170 26.87 ENSRNOT00000031979
ras homolog family member J
chr8_-_87419564 26.72 ENSRNOT00000015365
filamin A interacting protein 1
chr9_-_88256115 26.57 ENSRNOT00000076472
collagen type IV alpha 4 chain
chr10_+_71159869 26.49 ENSRNOT00000075977
ENSRNOT00000047427
HNF1 homeobox B
chr6_-_39363367 26.36 ENSRNOT00000088687
ENSRNOT00000065531
family with sequence similarity 84, member A
chr18_+_30527705 25.54 ENSRNOT00000027168
protocadherin beta 14
chr13_+_80125391 25.43 ENSRNOT00000044190
microRNA 199a-2
chr3_+_113318563 24.73 ENSRNOT00000089230
creatine kinase, mitochondrial 1
chr10_+_42614713 24.49 ENSRNOT00000081136
ENSRNOT00000073148
glutamate ionotropic receptor AMPA type subunit 1
chr8_-_107656861 24.10 ENSRNOT00000050374
muscle RAS oncogene homolog
chr1_-_236900904 24.02 ENSRNOT00000066846

chr18_+_29960072 23.84 ENSRNOT00000071366

chr6_-_109935533 23.71 ENSRNOT00000013516
transforming growth factor, beta 3
chr6_-_23291568 23.41 ENSRNOT00000085708
CAP-GLY domain containing linker protein family, member 4
chr11_-_65845418 23.31 ENSRNOT00000091057
follistatin-like 1
chr3_+_14482388 23.29 ENSRNOT00000025857
gelsolin
chr4_-_17594598 23.29 ENSRNOT00000008936
semaphorin 3E
chr11_+_33863500 23.25 ENSRNOT00000072384
carbonyl reductase [NADPH] 1-like
chr2_-_184993341 23.13 ENSRNOT00000071580
family with sequence similarity 160, member A1
chr17_+_5513930 22.96 ENSRNOT00000091370
ATP/GTP binding protein 1
chrX_-_139916883 22.84 ENSRNOT00000090442
glypican 3
chrX_-_142131545 22.44 ENSRNOT00000077402
fibroblast growth factor 13
chr18_+_30036887 22.44 ENSRNOT00000077824
protocadherin alpha 4
chr10_+_84135116 21.59 ENSRNOT00000031035
homeo box B7
chr8_+_23113048 21.52 ENSRNOT00000029577
calponin 1
chr10_-_86690815 21.07 ENSRNOT00000012537
nuclear receptor subfamily 1, group D, member 1
chr18_+_30562178 20.94 ENSRNOT00000040998
protocadherin beta-16-like
chr18_+_58270410 20.88 ENSRNOT00000067554
APC down-regulated 1
chr3_+_139695028 20.68 ENSRNOT00000089098
solute carrier family 24 member 3
chr8_-_72841496 20.29 ENSRNOT00000057641
ENSRNOT00000040808
ENSRNOT00000085894
ENSRNOT00000024575
ENSRNOT00000048044
ENSRNOT00000024493
tropomyosin 1, alpha
chr10_+_23661013 20.19 ENSRNOT00000076664
early B-cell factor 1
chr3_-_101547478 20.17 ENSRNOT00000006203
fin bud initiation factor homolog (zebrafish)
chr2_-_185303610 20.05 ENSRNOT00000093479
ENSRNOT00000046286
protease, serine 48
chr11_+_33812989 20.02 ENSRNOT00000042283
ENSRNOT00000075985
carbonyl reductase 1
chr7_+_58814805 19.87 ENSRNOT00000005909
tetraspanin 8
chr19_+_568287 19.62 ENSRNOT00000016419
cadherin 16
chrX_+_105537602 19.57 ENSRNOT00000029833
armadillo repeat containing, X-linked 1
chr2_+_251200686 19.49 ENSRNOT00000019210
collagen type XXIV alpha 1 chain
chr18_+_29972808 19.23 ENSRNOT00000074051
protocadherin alpha 4
chr16_+_54332660 19.20 ENSRNOT00000037685
microtubule associated tumor suppressor 1
chr2_-_79078258 19.19 ENSRNOT00000031170
F-box and leucine-rich repeat protein 7
chr2_+_196655469 18.97 ENSRNOT00000028730
cathepsin K
chr3_+_113818872 18.81 ENSRNOT00000044158
cancer susceptibility candidate 4
chr20_+_44060731 18.79 ENSRNOT00000000737
laminin subunit alpha 4
chr4_+_153330069 18.72 ENSRNOT00000015560
solute carrier family 25 member 18
chr12_-_29743705 18.71 ENSRNOT00000001185
calneuron 1
chr12_-_5685448 18.70 ENSRNOT00000077167
FRY microtubule binding protein
chr18_-_37096132 18.59 ENSRNOT00000041188
protein phosphatase 2, regulatory subunit B, beta
chr18_+_30004565 18.57 ENSRNOT00000027393
protocadherin alpha 4
chr14_+_86922223 18.54 ENSRNOT00000086468
receptor activity modifying protein 3
chr10_+_92337879 18.52 ENSRNOT00000042984
microtubule-associated protein tau
chrX_-_115073890 18.48 ENSRNOT00000006638
calpain 6
chr18_+_30890869 18.39 ENSRNOT00000060466
protocadherin gamma subfamily B, 6
chr18_+_30017918 18.30 ENSRNOT00000079794
protocadherin alpha 4
chr1_+_66898946 18.27 ENSRNOT00000074063
zinc finger protein 551
chr8_-_82641536 18.22 ENSRNOT00000014491
secretogranin III
chr14_+_70780623 18.20 ENSRNOT00000083871
ENSRNOT00000058803
LIM domain binding 2
chr9_+_60039297 18.18 ENSRNOT00000016262
solute carrier family 39 member 10
chr13_-_86671515 18.11 ENSRNOT00000082869

chr8_-_17525906 18.01 ENSRNOT00000007855
N-acetylated alpha-linked acidic dipeptidase 2
chr1_+_72860218 18.00 ENSRNOT00000024547
synaptotagmin 5
chr6_+_99433550 17.80 ENSRNOT00000079359
ENSRNOT00000008504
heat shock protein family A member 2
chr10_-_32471454 17.72 ENSRNOT00000003224
sarcoglycan, delta
chr10_+_3411380 17.67 ENSRNOT00000004346
similar to RIKEN cDNA 2900011O08
chr5_-_72000318 17.65 ENSRNOT00000029187

chr6_-_38228379 17.61 ENSRNOT00000084924
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr6_-_125723944 17.59 ENSRNOT00000007004
fibulin 5
chr7_+_38819771 17.53 ENSRNOT00000006109
lumican
chr1_+_89008117 17.52 ENSRNOT00000028401
heat shock protein family B (small) member 6
chr7_+_120153184 17.46 ENSRNOT00000013538
galectin 1
chrX_+_86126157 17.46 ENSRNOT00000006992
kelch-like family member 4
chr18_+_29951094 17.45 ENSRNOT00000027402
protocadherin alpha-1-like
chrX_+_119390013 17.44 ENSRNOT00000074269
angiotensin II receptor, type 2
chr1_-_164308317 17.32 ENSRNOT00000022983
serpin family H member 1
chr18_+_30381322 17.29 ENSRNOT00000027216
protocadherin beta 3
chr10_+_74871523 17.19 ENSRNOT00000076995
ENSRNOT00000076026
ENSRNOT00000088581
ENSRNOT00000076701
septin 4
chr1_-_250626844 17.16 ENSRNOT00000077135
N-acylsphingosine amidohydrolase 2
chr3_+_113251778 17.10 ENSRNOT00000083005
microtubule-associated protein 1A
chr1_+_44311513 16.98 ENSRNOT00000065386
T-cell lymphoma invasion and metastasis 2
chr1_+_64928503 16.86 ENSRNOT00000086274
vomeronasal 2 receptor, 80
chr16_+_80908340 16.83 ENSRNOT00000057761
transmembrane and coiled-coil domains 3
chr9_-_44237117 16.81 ENSRNOT00000068496
similar to putative protein (5S487)
chr13_+_98311827 16.76 ENSRNOT00000082844
CDC42 binding protein kinase alpha
chr4_+_180291389 16.75 ENSRNOT00000002465
sarcospan
chr7_+_144647587 16.48 ENSRNOT00000022398
homeo box C4
chr17_-_15467320 16.47 ENSRNOT00000072490
ENSRNOT00000093561
osteoglycin
chr6_-_125723732 16.39 ENSRNOT00000084815
fibulin 5
chr2_+_54191538 16.33 ENSRNOT00000019524
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr7_+_140967282 16.29 ENSRNOT00000091306
pre-mRNA processing factor 40 homolog B
chr2_+_203768729 16.09 ENSRNOT00000018895
immunoglobulin superfamily, member 3
chr10_+_90930010 16.08 ENSRNOT00000003765
HIG1 hypoxia inducible domain family, member 1B
chr3_+_154043873 16.04 ENSRNOT00000072502
ENSRNOT00000034166
neuronatin
chr6_-_94980004 15.96 ENSRNOT00000006373
reticulon 1
chr6_+_3012804 15.79 ENSRNOT00000061980
Rho guanine nucleotide exchange factor 33
chr11_-_11213821 15.65 ENSRNOT00000093706
roundabout guidance receptor 2
chr4_-_89281222 15.64 ENSRNOT00000010898
family with sequence similarity 13, member A
chr2_+_22910236 15.61 ENSRNOT00000078266
homer scaffolding protein 1
chr1_+_206900617 15.56 ENSRNOT00000054897
dedicator of cyto-kinesis 1
chr6_+_76675418 15.52 ENSRNOT00000076169
ENSRNOT00000010948
ENSRNOT00000082286
breast cancer metastasis-suppressor 1-like
breast cancer metastasis-suppressor 1-like
chr11_-_64583994 15.48 ENSRNOT00000004289
beta-1,4-galactosyltransferase 4
chr2_-_123193130 15.42 ENSRNOT00000019554
annexin A5
chr4_+_28989115 15.28 ENSRNOT00000075326
G protein subunit gamma 11
chr16_+_49266903 15.23 ENSRNOT00000014704
solute carrier family 25 member 4
chr14_-_43143973 15.20 ENSRNOT00000003248
ubiquitin C-terminal hydrolase L1
chr18_+_30550877 15.17 ENSRNOT00000027164
protocadherin beta-7-like
chr5_+_22392732 15.06 ENSRNOT00000087182
clavesin 1
chr3_+_14889510 15.05 ENSRNOT00000080760
DAB2 interacting protein
chr13_-_73819896 15.01 ENSRNOT00000036392
family with sequence similarity 163, member A
chr18_+_30010918 14.94 ENSRNOT00000084132
protocadherin alpha 4
chr1_-_80331626 14.81 ENSRNOT00000022577

chr3_+_132560506 14.80 ENSRNOT00000005920
serine palmitoyltransferase, long chain base subunit 3
chr7_-_121232741 14.72 ENSRNOT00000023196
platelet derived growth factor subunit B
chr11_-_62128044 14.67 ENSRNOT00000093141
zinc finger and BTB domain containing 20
chrX_-_66602458 14.61 ENSRNOT00000076510
ENSRNOT00000017429
ectodysplasin A2 receptor
chr11_+_42945084 14.56 ENSRNOT00000002292
crystallin beta-gamma domain containing 3
chr18_-_28017925 14.45 ENSRNOT00000075420
leucine rich repeat transmembrane neuronal 2
chr2_-_46476203 14.38 ENSRNOT00000015217
NADH:ubiquinone oxidoreductase subunit S4
chr18_+_56364620 14.32 ENSRNOT00000068535
ENSRNOT00000086033
platelet derived growth factor receptor beta
chr18_+_61258911 14.31 ENSRNOT00000082403
zinc finger protein 532
chr1_+_40389638 14.27 ENSRNOT00000021471
pleckstrin homology and RhoGEF domain containing G1
chr1_-_270472866 14.26 ENSRNOT00000015979
sortilin-related VPS10 domain containing receptor 1
chr18_+_65155685 14.25 ENSRNOT00000081797
transcription factor 4
chr4_-_176922424 14.18 ENSRNOT00000055540
ATP binding cassette subfamily C member 9
chr3_+_129599353 14.12 ENSRNOT00000008734
synaptosomal-associated protein 25
chr1_-_62558033 13.99 ENSRNOT00000015520
zinc finger protein 40
chr8_-_114449956 13.94 ENSRNOT00000056414
collagen type VI alpha 6 chain
chr13_-_107886476 13.92 ENSRNOT00000077282
potassium two pore domain channel subfamily K member 2
chr18_-_55916220 13.78 ENSRNOT00000025934
synaptopodin
chr9_+_50526811 13.74 ENSRNOT00000036990
similar to RIKEN cDNA 1500015O10
chr1_+_41192824 13.73 ENSRNOT00000082133
estrogen receptor 1
chr4_+_113968995 13.69 ENSRNOT00000079511
rhotekin
chr2_-_184289126 13.57 ENSRNOT00000081678
F-box and WD repeat domain containing 7
chr15_+_4125373 13.52 ENSRNOT00000029615
ubiquitin specific peptidase 54
chr11_-_11214141 13.51 ENSRNOT00000065748
roundabout guidance receptor 2
chr2_-_197991198 13.50 ENSRNOT00000056322
circadian associated repressor of transcription
chr2_+_237148941 13.39 ENSRNOT00000015116
dickkopf WNT signaling pathway inhibitor 2
chr4_+_114835064 13.38 ENSRNOT00000031964
rhotekin
chr3_+_79613171 13.36 ENSRNOT00000011467
ATP/GTP binding protein-like 2
chr8_-_62987182 13.21 ENSRNOT00000070885
immunoglobulin superfamily containing leucine-rich repeat 2
chr17_-_14679409 13.19 ENSRNOT00000020704
asporin
chr5_-_77945016 13.18 ENSRNOT00000076223
zinc finger protein 37
chr6_+_76349362 13.14 ENSRNOT00000043224
aldolase 1 A retrogene 2
chr6_-_114488880 13.12 ENSRNOT00000087560

chr5_-_28164326 12.95 ENSRNOT00000088165
solute carrier family 26 member 7
chr11_-_75144903 12.80 ENSRNOT00000002329
HRAS-like suppressor
chrX_-_105568343 12.72 ENSRNOT00000029807
armadillo repeat containing, X-linked 6
chr19_-_59991590 12.68 ENSRNOT00000091620

chr4_+_70252366 12.66 ENSRNOT00000073039
cell adhesion molecule L1-like
chr9_+_14529218 12.66 ENSRNOT00000016893
apolipoprotein B mRNA editing enzyme catalytic subunit 2
chr8_+_99880073 12.64 ENSRNOT00000010765
phospholipid scramblase 4
chr8_-_109621408 12.62 ENSRNOT00000087398
protein phosphatase 2, regulatory subunit B'', alpha
chr1_+_171793782 12.61 ENSRNOT00000081351
olfactomedin-like 1
chr8_-_109576353 12.57 ENSRNOT00000010320
protein phosphatase 2, regulatory subunit B'', alpha
chr10_+_17327275 12.52 ENSRNOT00000005486
ubiquitin domain containing 2
chr1_+_252409268 12.46 ENSRNOT00000026219
lipase, family member M
chr11_+_75434197 12.44 ENSRNOT00000032569
Mab-21 domain containing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfatc2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
24.2 72.6 GO:0097325 melanocyte proliferation(GO:0097325)
16.1 48.3 GO:0072254 metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254)
15.5 46.6 GO:0071529 cementum mineralization(GO:0071529)
10.7 32.0 GO:1901146 mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
10.1 80.6 GO:0051694 pointed-end actin filament capping(GO:0051694)
9.6 57.4 GO:1901843 membrane depolarization during bundle of His cell action potential(GO:0086048) positive regulation of high voltage-gated calcium channel activity(GO:1901843)
9.1 27.2 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
9.0 27.0 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
8.9 44.3 GO:0061743 motor learning(GO:0061743)
8.7 34.7 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
8.4 25.2 GO:0090249 cell motility involved in somitogenic axis elongation(GO:0090247) regulation of cell motility involved in somitogenic axis elongation(GO:0090249)
7.9 23.7 GO:1905075 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
7.8 23.3 GO:1903903 protein processing in phagocytic vesicle(GO:1900756) regulation of establishment of T cell polarity(GO:1903903) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
7.7 30.8 GO:1901662 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
7.2 43.0 GO:0033227 dsRNA transport(GO:0033227)
7.0 21.1 GO:0060086 circadian temperature homeostasis(GO:0060086)
6.9 27.7 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
6.8 33.9 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
6.8 20.3 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
6.4 19.1 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
6.1 30.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
5.8 29.2 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
5.8 17.4 GO:0035566 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) negative regulation of icosanoid secretion(GO:0032304) regulation of metanephros size(GO:0035566)
5.7 22.8 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
5.5 16.5 GO:1990792 response to glial cell derived neurotrophic factor(GO:1990790) cellular response to glial cell derived neurotrophic factor(GO:1990792)
5.4 10.8 GO:0036023 embryonic skeletal limb joint morphogenesis(GO:0036023)
5.2 36.3 GO:0035610 protein side chain deglutamylation(GO:0035610)
5.1 15.3 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
5.0 10.0 GO:1903181 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
4.8 14.5 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
4.7 14.1 GO:1990926 short-term synaptic potentiation(GO:1990926)
4.7 18.7 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
4.6 9.3 GO:0035564 regulation of kidney size(GO:0035564)
4.6 13.9 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
4.4 17.8 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
4.3 34.1 GO:0070163 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
3.9 27.1 GO:0022605 oogenesis stage(GO:0022605)
3.8 15.2 GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity(GO:2000277)
3.8 15.1 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
3.6 10.9 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
3.6 14.3 GO:0072223 cell migration involved in vasculogenesis(GO:0035441) VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091) metanephric glomerular mesangium development(GO:0072223) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
3.5 10.6 GO:0001827 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
3.5 10.6 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
3.5 24.5 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
3.5 17.5 GO:0002317 plasma cell differentiation(GO:0002317)
3.4 13.8 GO:0098886 modification of dendritic spine(GO:0098886)
3.4 17.2 GO:0030382 sperm mitochondrion organization(GO:0030382)
3.4 13.7 GO:1990375 baculum development(GO:1990375)
3.4 34.0 GO:0048251 elastic fiber assembly(GO:0048251)
3.3 9.9 GO:0032474 otolith morphogenesis(GO:0032474)
3.3 9.8 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
3.2 9.6 GO:0071898 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
3.2 22.4 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
3.2 464.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
3.2 25.4 GO:0002091 negative regulation of receptor internalization(GO:0002091)
3.2 12.7 GO:0016554 cytidine to uridine editing(GO:0016554)
3.2 19.0 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
3.1 9.3 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
3.1 18.5 GO:1900034 regulation of cellular response to heat(GO:1900034)
3.1 21.5 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
3.1 24.4 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
3.0 12.0 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
3.0 8.9 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
3.0 41.6 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
3.0 8.9 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
2.9 14.7 GO:0038007 netrin-activated signaling pathway(GO:0038007)
2.9 17.5 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
2.9 8.6 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
2.8 14.2 GO:0060327 cytoplasmic actin-based contraction involved in cell motility(GO:0060327)
2.8 25.3 GO:0070459 prolactin secretion(GO:0070459)
2.8 35.8 GO:0001886 endothelial cell morphogenesis(GO:0001886)
2.8 8.3 GO:0006532 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
2.7 10.9 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
2.7 2.7 GO:0071298 cellular response to L-ascorbic acid(GO:0071298)
2.7 5.4 GO:0010710 regulation of collagen catabolic process(GO:0010710) negative regulation of extracellular matrix disassembly(GO:0010716)
2.7 10.7 GO:0072092 ureteric bud invasion(GO:0072092)
2.7 10.7 GO:0071288 cellular response to mercury ion(GO:0071288)
2.6 10.5 GO:0035989 tendon development(GO:0035989)
2.6 10.2 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962) response to prostaglandin F(GO:0034696)
2.5 17.7 GO:0021814 cell motility involved in cerebral cortex radial glia guided migration(GO:0021814)
2.5 12.4 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
2.4 4.9 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
2.4 19.3 GO:0015871 choline transport(GO:0015871)
2.4 9.5 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
2.4 7.1 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
2.3 4.7 GO:0001757 somite specification(GO:0001757)
2.3 9.0 GO:2001013 positive regulation of macrophage apoptotic process(GO:2000111) epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
2.2 11.2 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
2.2 4.5 GO:0001951 intestinal D-glucose absorption(GO:0001951)
2.2 26.6 GO:0032836 glomerular basement membrane development(GO:0032836)
2.2 13.2 GO:0042483 negative regulation of odontogenesis(GO:0042483)
2.2 6.6 GO:0032218 riboflavin transport(GO:0032218)
2.1 10.4 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
2.1 10.3 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
2.1 12.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
2.1 26.9 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
2.1 18.5 GO:0086103 G-protein coupled receptor signaling pathway involved in heart process(GO:0086103)
2.0 4.1 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
2.0 5.9 GO:0008355 olfactory learning(GO:0008355) olefin metabolic process(GO:1900673)
2.0 3.9 GO:1905066 regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
1.9 17.4 GO:0019896 axonal transport of mitochondrion(GO:0019896)
1.9 11.6 GO:0048669 collateral sprouting in absence of injury(GO:0048669)
1.9 11.3 GO:0060721 regulation of spongiotrophoblast cell proliferation(GO:0060721) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
1.8 8.8 GO:0045919 positive regulation of cytolysis(GO:0045919)
1.7 6.9 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
1.7 11.8 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
1.7 8.4 GO:0033026 negative regulation of mast cell apoptotic process(GO:0033026) mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
1.7 6.7 GO:0030167 proteoglycan catabolic process(GO:0030167)
1.7 5.0 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
1.7 29.9 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
1.7 18.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
1.6 16.1 GO:0032808 lacrimal gland development(GO:0032808)
1.6 17.7 GO:0007097 nuclear migration(GO:0007097)
1.6 7.9 GO:0051660 establishment of centrosome localization(GO:0051660)
1.6 7.8 GO:0042780 tRNA 3'-end processing(GO:0042780)
1.5 18.4 GO:0033139 regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
1.5 18.0 GO:0042135 neurotransmitter catabolic process(GO:0042135)
1.5 5.8 GO:0007172 signal complex assembly(GO:0007172)
1.4 4.3 GO:0010796 regulation of multivesicular body size(GO:0010796)
1.4 7.1 GO:0090394 negative regulation of excitatory postsynaptic potential(GO:0090394)
1.4 7.1 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
1.4 13.9 GO:0070314 G1 to G0 transition(GO:0070314)
1.4 23.3 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
1.4 2.7 GO:1903243 negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
1.3 14.8 GO:0046520 sphingoid biosynthetic process(GO:0046520)
1.3 18.6 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
1.3 5.1 GO:0021564 vagus nerve development(GO:0021564)
1.3 8.9 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
1.3 2.5 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
1.3 5.0 GO:0003406 retinal pigment epithelium development(GO:0003406)
1.2 7.5 GO:0072675 osteoclast fusion(GO:0072675)
1.2 1.2 GO:2000297 negative regulation of synapse maturation(GO:2000297)
1.2 4.9 GO:0001712 ectodermal cell fate commitment(GO:0001712)
1.2 8.4 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
1.2 21.6 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
1.2 3.6 GO:0030091 protein repair(GO:0030091)
1.2 3.5 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
1.2 18.7 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
1.1 12.6 GO:0017121 phospholipid scrambling(GO:0017121)
1.1 16.0 GO:0021819 layer formation in cerebral cortex(GO:0021819)
1.1 10.1 GO:2000381 negative regulation of mesoderm development(GO:2000381)
1.1 14.4 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
1.1 14.3 GO:0042118 endothelial cell activation(GO:0042118)
1.1 5.4 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
1.1 4.3 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
1.1 4.3 GO:0060591 chondroblast differentiation(GO:0060591)
1.1 12.8 GO:0046485 ether lipid metabolic process(GO:0046485)
1.0 10.2 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
1.0 2.0 GO:0043932 ossification involved in bone remodeling(GO:0043932)
1.0 6.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
1.0 3.0 GO:0061443 endocardial cushion cell differentiation(GO:0061443)
1.0 2.0 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
1.0 7.8 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
1.0 15.6 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
1.0 2.9 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
1.0 10.6 GO:0051583 dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934)
0.9 7.4 GO:0030049 muscle filament sliding(GO:0030049)
0.9 0.9 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.9 1.8 GO:0097213 regulation of lysosomal membrane permeability(GO:0097213) positive regulation of lysosomal membrane permeability(GO:0097214)
0.9 7.2 GO:0046710 GDP metabolic process(GO:0046710)
0.9 9.0 GO:0048385 regulation of retinoic acid receptor signaling pathway(GO:0048385)
0.9 12.2 GO:0032060 bleb assembly(GO:0032060)
0.9 18.2 GO:0010669 epithelial structure maintenance(GO:0010669)
0.9 17.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.8 11.0 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.8 26.2 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.8 9.8 GO:0036159 inner dynein arm assembly(GO:0036159)
0.8 9.6 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.8 8.7 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.8 1.6 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.8 20.2 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.8 2.3 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.8 13.0 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.8 11.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.7 5.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.7 1.5 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.7 17.5 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.7 14.4 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.7 7.8 GO:0051255 spindle midzone assembly(GO:0051255)
0.7 19.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.7 5.7 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.7 2.1 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.7 4.1 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.7 19.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.7 12.2 GO:0060992 response to fungicide(GO:0060992)
0.7 9.2 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.6 9.0 GO:1903830 magnesium ion transport(GO:0015693) magnesium ion transmembrane transport(GO:1903830)
0.6 12.1 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.6 11.4 GO:0051642 centrosome localization(GO:0051642)
0.6 6.5 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.6 3.5 GO:0035865 cellular response to potassium ion(GO:0035865)
0.6 17.6 GO:0090218 positive regulation of lipid kinase activity(GO:0090218)
0.6 5.8 GO:0001778 plasma membrane repair(GO:0001778)
0.6 1.7 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.6 8.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.6 6.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.6 2.8 GO:1904923 regulation of mitophagy in response to mitochondrial depolarization(GO:1904923)
0.6 4.4 GO:0019695 choline metabolic process(GO:0019695)
0.5 2.2 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.5 2.2 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.5 4.8 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.5 3.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.5 7.0 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.5 7.0 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.5 8.5 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.5 16.5 GO:0048662 negative regulation of smooth muscle cell proliferation(GO:0048662)
0.5 3.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.5 88.7 GO:0060070 canonical Wnt signaling pathway(GO:0060070)
0.5 1.6 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.5 6.6 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.5 18.0 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.5 1.5 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.5 11.2 GO:0045475 locomotor rhythm(GO:0045475)
0.5 2.4 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.5 1.9 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.5 38.2 GO:0001578 microtubule bundle formation(GO:0001578)
0.5 1.4 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.5 17.7 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.4 4.0 GO:0007000 nucleolus organization(GO:0007000)
0.4 3.1 GO:0010193 response to ozone(GO:0010193)
0.4 3.6 GO:0038161 prolactin signaling pathway(GO:0038161)
0.4 1.3 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.4 18.8 GO:0050873 brown fat cell differentiation(GO:0050873)
0.4 1.7 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.4 6.1 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.4 3.4 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.4 0.8 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.4 18.2 GO:0034605 cellular response to heat(GO:0034605)
0.4 7.0 GO:0070208 protein heterotrimerization(GO:0070208)
0.4 18.2 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.4 14.4 GO:0045773 positive regulation of axon extension(GO:0045773)
0.4 1.2 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.4 5.0 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.4 1.1 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.4 2.2 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.4 10.5 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.4 9.2 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.4 6.2 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.4 22.5 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.4 9.8 GO:0060976 coronary vasculature development(GO:0060976)
0.4 8.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.4 3.2 GO:0045836 positive regulation of meiotic nuclear division(GO:0045836)
0.3 5.5 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.3 1.3 GO:1904823 purine nucleobase transmembrane transport(GO:1904823)
0.3 65.7 GO:0001822 kidney development(GO:0001822)
0.3 2.3 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.3 9.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.3 1.9 GO:0030321 transepithelial chloride transport(GO:0030321)
0.3 1.6 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.3 1.6 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.3 16.8 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.3 2.1 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.3 10.3 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.3 28.1 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.3 1.4 GO:0060005 vestibular reflex(GO:0060005)
0.3 5.9 GO:0007520 myoblast fusion(GO:0007520)
0.3 1.6 GO:0006621 protein retention in ER lumen(GO:0006621)
0.3 2.6 GO:0000338 protein deneddylation(GO:0000338)
0.3 2.8 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.2 2.0 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.2 10.6 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.2 0.7 GO:0006431 methionyl-tRNA aminoacylation(GO:0006431)
0.2 4.1 GO:0042026 protein refolding(GO:0042026)
0.2 1.4 GO:0070970 interleukin-2 secretion(GO:0070970)
0.2 1.9 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.2 5.4 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 2.6 GO:0015825 L-serine transport(GO:0015825)
0.2 5.3 GO:0032873 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.2 4.8 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.2 5.1 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.2 13.6 GO:0006096 glycolytic process(GO:0006096)
0.2 5.0 GO:0001522 pseudouridine synthesis(GO:0001522)
0.2 9.6 GO:0031016 pancreas development(GO:0031016)
0.2 11.5 GO:0007368 determination of left/right symmetry(GO:0007368)
0.2 4.7 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.2 29.5 GO:0006941 striated muscle contraction(GO:0006941)
0.2 1.4 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.2 15.3 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.2 1.1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.2 1.6 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.2 11.6 GO:1901800 positive regulation of proteasomal protein catabolic process(GO:1901800)
0.2 16.3 GO:0006665 sphingolipid metabolic process(GO:0006665)
0.2 3.0 GO:0090161 Golgi ribbon formation(GO:0090161)
0.2 1.2 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.2 12.0 GO:0016575 histone deacetylation(GO:0016575)
0.2 12.9 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.1 1.4 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 4.0 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 1.0 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 3.1 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 2.0 GO:0048240 sperm capacitation(GO:0048240)
0.1 1.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.6 GO:0051014 actin filament severing(GO:0051014)
0.1 1.7 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.1 1.7 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 3.3 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.1 0.4 GO:0006021 inositol biosynthetic process(GO:0006021)
0.1 3.4 GO:0021762 substantia nigra development(GO:0021762)
0.1 9.6 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.1 2.8 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.1 0.6 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.1 1.2 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 0.4 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 5.9 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 1.2 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 1.4 GO:0045116 protein neddylation(GO:0045116)
0.1 0.3 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 2.4 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.1 1.2 GO:0006415 translational termination(GO:0006415)
0.1 3.8 GO:0007224 smoothened signaling pathway(GO:0007224)
0.1 5.5 GO:0016579 protein deubiquitination(GO:0016579)
0.1 2.5 GO:0055123 digestive system development(GO:0055123)
0.0 2.0 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.9 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 1.9 GO:0060047 heart contraction(GO:0060047)
0.0 0.6 GO:0048806 genitalia development(GO:0048806)
0.0 1.1 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 2.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.6 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.1 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.0 38.4 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 0.2 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.2 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.5 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 2.5 GO:0006486 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
12.4 87.0 GO:0071438 invadopodium membrane(GO:0071438)
10.7 64.0 GO:0016012 sarcoglycan complex(GO:0016012)
9.5 28.5 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
9.2 27.7 GO:0005945 6-phosphofructokinase complex(GO:0005945)
8.7 34.7 GO:0005588 collagen type V trimer(GO:0005588)
6.8 34.0 GO:0071953 elastic fiber(GO:0071953)
5.7 28.3 GO:0005927 muscle tendon junction(GO:0005927)
5.0 15.1 GO:1990032 parallel fiber(GO:1990032)
4.8 57.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
4.6 18.5 GO:0045298 tubulin complex(GO:0045298)
4.6 13.8 GO:0097444 spine apparatus(GO:0097444)
4.5 53.5 GO:0098839 postsynaptic density membrane(GO:0098839)
3.9 23.3 GO:0030478 actin cap(GO:0030478)
3.9 19.3 GO:1990769 proximal neuron projection(GO:1990769)
3.7 44.3 GO:0043083 synaptic cleft(GO:0043083)
3.5 14.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
3.5 10.5 GO:0005592 collagen type XI trimer(GO:0005592)
3.5 17.5 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
3.3 26.6 GO:0098645 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
3.1 15.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
2.9 43.6 GO:0072687 meiotic spindle(GO:0072687)
2.9 20.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
2.8 14.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
2.3 9.3 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
2.0 7.9 GO:0005593 FACIT collagen trimer(GO:0005593)
1.9 69.8 GO:0046930 pore complex(GO:0046930)
1.9 22.8 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
1.9 14.8 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
1.8 8.8 GO:1990130 Iml1 complex(GO:1990130)
1.8 12.3 GO:1990357 terminal web(GO:1990357)
1.7 13.9 GO:0044305 calyx of Held(GO:0044305)
1.7 17.2 GO:0005641 nuclear envelope lumen(GO:0005641)
1.7 10.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
1.7 17.2 GO:0097227 septin complex(GO:0031105) sperm annulus(GO:0097227)
1.7 5.0 GO:0031095 platelet dense tubular network membrane(GO:0031095)
1.6 45.5 GO:0032839 dendrite cytoplasm(GO:0032839)
1.6 3.1 GO:0034774 secretory granule lumen(GO:0034774)
1.5 10.5 GO:0001739 sex chromatin(GO:0001739)
1.5 6.0 GO:0036156 inner dynein arm(GO:0036156)
1.3 35.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
1.3 39.5 GO:0030673 axolemma(GO:0030673)
1.2 31.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
1.2 12.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
1.2 16.2 GO:0043202 lysosomal lumen(GO:0043202)
1.1 23.7 GO:0070822 Sin3-type complex(GO:0070822)
1.1 10.6 GO:0034464 BBSome(GO:0034464)
1.0 16.3 GO:0071004 U2-type prespliceosome(GO:0071004)
1.0 6.1 GO:1990393 Cul7-RING ubiquitin ligase complex(GO:0031467) 3M complex(GO:1990393)
1.0 3.9 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
1.0 15.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
1.0 5.8 GO:0005826 actomyosin contractile ring(GO:0005826)
1.0 6.7 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
1.0 5.7 GO:0032437 cuticular plate(GO:0032437)
0.9 0.9 GO:0044299 C-fiber(GO:0044299)
0.9 7.1 GO:0032584 growth cone membrane(GO:0032584)
0.9 8.0 GO:0030314 junctional membrane complex(GO:0030314)
0.9 8.6 GO:0045180 basal cortex(GO:0045180)
0.9 18.8 GO:0005605 basal lamina(GO:0005605)
0.8 16.9 GO:0005614 interstitial matrix(GO:0005614)
0.8 19.0 GO:0043034 costamere(GO:0043034)
0.8 6.2 GO:0031931 TORC1 complex(GO:0031931)
0.8 21.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.8 6.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.7 31.4 GO:0030315 T-tubule(GO:0030315)
0.7 2.1 GO:0000802 transverse filament(GO:0000802)
0.7 2.7 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.7 7.4 GO:0032982 myosin filament(GO:0032982)
0.7 33.2 GO:0005581 collagen trimer(GO:0005581)
0.7 28.2 GO:1904115 axon cytoplasm(GO:1904115)
0.7 23.4 GO:0016459 myosin complex(GO:0016459)
0.6 10.9 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.6 16.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.6 36.9 GO:0042641 actomyosin(GO:0042641)
0.6 7.9 GO:0097539 ciliary transition fiber(GO:0097539)
0.6 3.5 GO:0035189 Rb-E2F complex(GO:0035189)
0.6 1.7 GO:0098855 HCN channel complex(GO:0098855)
0.6 33.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.6 13.7 GO:0060077 inhibitory synapse(GO:0060077)
0.6 3.4 GO:0005869 dynactin complex(GO:0005869)
0.6 41.1 GO:0014704 intercalated disc(GO:0014704)
0.5 8.0 GO:0032433 filopodium tip(GO:0032433)
0.5 3.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.5 8.4 GO:0030175 filopodium(GO:0030175)
0.5 16.0 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.5 9.4 GO:0031430 M band(GO:0031430)
0.5 10.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.5 7.2 GO:0005883 neurofilament(GO:0005883)
0.5 10.5 GO:0030286 dynein complex(GO:0030286)
0.5 1.9 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.5 0.9 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.5 5.5 GO:0005861 troponin complex(GO:0005861)
0.4 121.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.4 1.7 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.4 6.4 GO:0044291 cell-cell contact zone(GO:0044291)
0.4 13.6 GO:0008180 COP9 signalosome(GO:0008180)
0.4 5.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.4 23.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.4 18.4 GO:0016235 aggresome(GO:0016235)
0.4 441.4 GO:0005887 integral component of plasma membrane(GO:0005887)
0.4 57.0 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.4 9.6 GO:0097546 ciliary base(GO:0097546)
0.4 76.0 GO:0030427 site of polarized growth(GO:0030427)
0.4 25.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.4 23.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.4 16.5 GO:0031901 early endosome membrane(GO:0031901)
0.3 2.0 GO:0036128 CatSper complex(GO:0036128)
0.3 23.0 GO:0043197 dendritic spine(GO:0043197)
0.3 54.4 GO:0031012 extracellular matrix(GO:0031012)
0.3 32.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.3 1.2 GO:0031417 NatC complex(GO:0031417)
0.3 3.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.3 5.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.3 8.5 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.3 14.4 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.3 4.8 GO:0030125 clathrin vesicle coat(GO:0030125)
0.3 17.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 2.8 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 31.1 GO:0043209 myelin sheath(GO:0043209)
0.2 17.5 GO:0030017 sarcomere(GO:0030017)
0.2 1.4 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.2 1.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.2 21.3 GO:0043235 receptor complex(GO:0043235)
0.2 6.9 GO:0098858 actin-based cell projection(GO:0098858)
0.2 1.4 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.2 12.2 GO:0005923 bicellular tight junction(GO:0005923)
0.2 10.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 2.9 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 33.3 GO:0045177 apical part of cell(GO:0045177)
0.1 0.4 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 4.6 GO:0005876 spindle microtubule(GO:0005876)
0.1 7.5 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.9 GO:0042581 primary lysosome(GO:0005766) specific granule(GO:0042581) azurophil granule(GO:0042582)
0.1 18.0 GO:0015629 actin cytoskeleton(GO:0015629)
0.1 2.1 GO:0042383 sarcolemma(GO:0042383)
0.1 3.0 GO:0005844 polysome(GO:0005844)
0.1 1.4 GO:0005922 connexon complex(GO:0005922)
0.1 11.5 GO:0001650 fibrillar center(GO:0001650)
0.1 17.3 GO:0005925 focal adhesion(GO:0005925)
0.1 1.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.3 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 3.1 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.6 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 2.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 2.4 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
19.1 57.4 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
15.5 46.6 GO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
7.3 36.6 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
7.3 72.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
6.9 27.7 GO:0003872 6-phosphofructokinase activity(GO:0003872)
6.4 19.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
6.2 30.8 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
5.8 23.3 GO:0045159 myosin II binding(GO:0045159)
5.3 26.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
5.2 15.5 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
5.0 89.5 GO:0005523 tropomyosin binding(GO:0005523)
4.8 14.3 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
4.8 14.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
4.7 14.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
4.6 18.5 GO:0099609 microtubule lateral binding(GO:0099609)
4.6 18.2 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
4.2 33.6 GO:0043199 sulfate binding(GO:0043199)
4.0 31.7 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
3.9 27.0 GO:0031852 mu-type opioid receptor binding(GO:0031852)
3.8 15.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
3.8 11.3 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
3.7 18.7 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
3.7 11.0 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
3.6 10.9 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
3.6 25.0 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
3.5 38.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
3.5 24.7 GO:0004111 creatine kinase activity(GO:0004111)
3.4 10.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
3.4 13.7 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
3.4 27.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
3.2 15.8 GO:0004945 angiotensin type II receptor activity(GO:0004945)
3.1 15.6 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
3.1 9.3 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
3.1 15.3 GO:0050816 phosphothreonine binding(GO:0050816)
3.0 14.8 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
3.0 8.9 GO:0035939 microsatellite binding(GO:0035939)
2.9 14.7 GO:0005042 netrin receptor activity(GO:0005042)
2.9 11.7 GO:0015220 choline transmembrane transporter activity(GO:0015220)
2.9 11.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
2.9 17.2 GO:0017040 ceramidase activity(GO:0017040)
2.8 33.9 GO:0008046 axon guidance receptor activity(GO:0008046)
2.8 13.9 GO:0022841 potassium ion leak channel activity(GO:0022841)
2.8 8.3 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
2.6 10.5 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
2.5 15.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
2.4 41.6 GO:0008179 adenylate cyclase binding(GO:0008179)
2.4 12.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
2.3 9.4 GO:0002046 opsin binding(GO:0002046)
2.3 18.2 GO:0030274 LIM domain binding(GO:0030274)
2.3 27.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
2.2 6.6 GO:0001605 adrenomedullin receptor activity(GO:0001605)
2.2 6.6 GO:0032217 riboflavin transporter activity(GO:0032217)
2.1 12.7 GO:0004126 cytidine deaminase activity(GO:0004126)
2.0 6.1 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
2.0 5.9 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
1.9 23.3 GO:0030215 semaphorin receptor binding(GO:0030215)
1.9 41.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
1.9 11.4 GO:0048030 disaccharide binding(GO:0048030)
1.9 13.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.8 18.4 GO:0005132 type I interferon receptor binding(GO:0005132)
1.8 11.0 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
1.8 12.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
1.7 6.9 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
1.7 10.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
1.7 15.2 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
1.6 4.9 GO:0030158 protein xylosyltransferase activity(GO:0030158)
1.6 8.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
1.6 9.6 GO:0030284 estrogen receptor activity(GO:0030284)
1.6 31.8 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
1.6 36.2 GO:0015288 porin activity(GO:0015288)
1.5 7.7 GO:0070052 collagen V binding(GO:0070052)
1.5 12.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
1.5 30.3 GO:0001222 transcription corepressor binding(GO:0001222)
1.5 6.0 GO:0016149 translation release factor activity, codon specific(GO:0016149)
1.5 4.4 GO:0003990 acetylcholinesterase activity(GO:0003990)
1.4 7.1 GO:0001601 peptide YY receptor activity(GO:0001601)
1.4 19.3 GO:0042043 neurexin family protein binding(GO:0042043)
1.4 35.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
1.4 5.4 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
1.3 22.9 GO:0001972 retinoic acid binding(GO:0001972)
1.3 13.4 GO:0039706 co-receptor binding(GO:0039706)
1.3 28.5 GO:0003746 translation elongation factor activity(GO:0003746)
1.2 8.7 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
1.2 83.1 GO:0005518 collagen binding(GO:0005518)
1.2 19.8 GO:0004180 carboxypeptidase activity(GO:0004180)
1.2 24.3 GO:0015299 solute:proton antiporter activity(GO:0015299)
1.2 8.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
1.2 3.6 GO:0004925 prolactin receptor activity(GO:0004925)
1.2 10.5 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
1.1 3.4 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
1.1 63.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
1.1 6.7 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
1.1 15.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
1.1 10.6 GO:0031432 titin binding(GO:0031432)
1.0 17.3 GO:0050431 transforming growth factor beta binding(GO:0050431)
1.0 9.0 GO:0003680 AT DNA binding(GO:0003680)
1.0 20.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
1.0 18.5 GO:0015026 coreceptor activity(GO:0015026)
1.0 7.6 GO:0071253 connexin binding(GO:0071253)
1.0 7.6 GO:0030957 Tat protein binding(GO:0030957)
0.9 41.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.9 15.7 GO:0017166 vinculin binding(GO:0017166)
0.9 21.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.9 20.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.9 3.6 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.9 7.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.9 7.0 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.9 13.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.8 565.6 GO:0005509 calcium ion binding(GO:0005509)
0.8 7.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.8 5.5 GO:0071532 ankyrin repeat binding(GO:0071532)
0.7 10.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.7 7.4 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.7 23.7 GO:0004407 histone deacetylase activity(GO:0004407)
0.7 19.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.7 12.3 GO:0002162 dystroglycan binding(GO:0002162)
0.7 63.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.7 8.0 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.7 9.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.7 21.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.6 1.9 GO:0052724 inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.6 63.4 GO:0016503 pheromone receptor activity(GO:0016503)
0.6 3.1 GO:0034235 GPI anchor binding(GO:0034235)
0.6 6.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.6 20.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.6 11.0 GO:0071837 HMG box domain binding(GO:0071837)
0.6 7.8 GO:0051787 misfolded protein binding(GO:0051787)
0.6 9.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.6 42.2 GO:0046332 SMAD binding(GO:0046332)
0.6 4.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.6 5.8 GO:0008432 JUN kinase binding(GO:0008432)
0.6 19.0 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.6 3.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.5 2.2 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.5 4.3 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.5 12.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.5 11.8 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.5 4.7 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.5 1.6 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.5 15.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.5 6.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.5 7.8 GO:0035174 histone serine kinase activity(GO:0035174)
0.5 12.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.5 8.1 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.5 4.7 GO:0050897 cobalt ion binding(GO:0050897)
0.5 5.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.5 10.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.4 1.3 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.4 2.0 GO:0036122 BMP binding(GO:0036122)
0.4 3.2 GO:0008494 translation activator activity(GO:0008494)
0.4 9.2 GO:0005109 frizzled binding(GO:0005109)
0.4 1.6 GO:0046923 ER retention sequence binding(GO:0046923)
0.4 2.0 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.4 1.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.4 7.0 GO:0008199 ferric iron binding(GO:0008199)
0.4 5.1 GO:0071617 lysophospholipid acyltransferase activity(GO:0071617)
0.4 5.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 2.4 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.3 1.4 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.3 5.0 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.3 7.8 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.3 2.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.3 0.9 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.3 13.5 GO:0019894 kinesin binding(GO:0019894)
0.3 6.8 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.3 5.1 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.3 10.7 GO:0070888 E-box binding(GO:0070888)
0.3 0.8 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.3 1.6 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.3 20.9 GO:0051082 unfolded protein binding(GO:0051082)
0.2 0.7 GO:0004825 methionine-tRNA ligase activity(GO:0004825)
0.2 2.8 GO:0001968 fibronectin binding(GO:0001968)
0.2 5.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 3.3 GO:0042166 acetylcholine-gated cation channel activity(GO:0022848) acetylcholine binding(GO:0042166)
0.2 20.2 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.2 2.6 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.2 2.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.2 5.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 1.4 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.2 1.4 GO:0097322 7SK snRNA binding(GO:0097322)
0.2 3.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 44.5 GO:0005096 GTPase activator activity(GO:0005096)
0.2 3.4 GO:0070840 dynein complex binding(GO:0070840)
0.2 5.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 3.1 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.2 2.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.2 6.6 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.2 0.9 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 1.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 2.8 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 3.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 3.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.4 GO:0008254 3'-nucleotidase activity(GO:0008254)
0.1 1.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 5.0 GO:0030507 spectrin binding(GO:0030507)
0.1 3.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 2.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 5.2 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 16.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 2.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 10.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.1 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 11.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.7 GO:0030332 cyclin binding(GO:0030332)
0.1 20.7 GO:0000287 magnesium ion binding(GO:0000287)
0.1 6.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 3.3 GO:0008237 metallopeptidase activity(GO:0008237)
0.1 1.0 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 1.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 7.3 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 3.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 2.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 32.8 GO:0005549 odorant binding(GO:0005549)
0.1 8.4 GO:0003774 motor activity(GO:0003774)
0.1 2.6 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.1 9.2 GO:0008017 microtubule binding(GO:0008017)
0.1 1.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 6.4 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.1 4.0 GO:0051015 actin filament binding(GO:0051015)
0.1 6.1 GO:0005179 hormone activity(GO:0005179)
0.1 2.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.6 GO:0008301 DNA binding, bending(GO:0008301)
0.0 2.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.3 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 2.3 GO:0008565 protein transporter activity(GO:0008565)
0.0 11.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.9 GO:0005244 voltage-gated ion channel activity(GO:0005244) voltage-gated channel activity(GO:0022832)
0.0 0.2 GO:0043015 gamma-tubulin binding(GO:0043015)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 115.8 NABA COLLAGENS Genes encoding collagen proteins
1.7 30.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
1.3 27.7 PID LPA4 PATHWAY LPA4-mediated signaling events
1.2 54.9 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
1.2 43.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
1.1 45.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
1.0 13.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.8 120.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.8 54.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.7 32.9 PID NETRIN PATHWAY Netrin-mediated signaling events
0.7 26.6 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.7 28.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.6 24.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.6 14.4 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.6 15.1 PID RAS PATHWAY Regulation of Ras family activation
0.6 5.2 PID S1P S1P2 PATHWAY S1P2 pathway
0.5 15.3 PID MYC PATHWAY C-MYC pathway
0.5 43.1 PID CMYB PATHWAY C-MYB transcription factor network
0.5 24.1 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.5 20.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.5 5.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.5 18.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.4 7.6 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.4 12.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.4 16.8 PID BMP PATHWAY BMP receptor signaling
0.4 10.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.4 3.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.4 15.3 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.3 9.9 PID ERBB4 PATHWAY ErbB4 signaling events
0.3 9.5 PID TNF PATHWAY TNF receptor signaling pathway
0.3 9.5 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.3 13.0 PID ATR PATHWAY ATR signaling pathway
0.3 9.2 PID P53 REGULATION PATHWAY p53 pathway
0.3 3.7 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.3 9.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.3 3.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 3.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 3.6 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.2 14.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 16.1 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.2 0.6 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 4.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.2 9.9 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.2 2.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 2.7 PID CDC42 PATHWAY CDC42 signaling events
0.1 4.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 3.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 1.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 0.9 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.1 14.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.6 PID ARF6 PATHWAY Arf6 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 47.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
3.0 8.9 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
2.5 7.6 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
2.4 42.6 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
2.2 33.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
2.1 8.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
2.0 119.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
1.7 47.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
1.7 48.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
1.6 25.8 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
1.6 28.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
1.6 17.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
1.5 19.0 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
1.4 22.8 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
1.3 23.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
1.0 39.8 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
1.0 37.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
1.0 10.0 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
1.0 24.9 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.9 13.8 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.9 15.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.9 18.0 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.9 10.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.9 16.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.8 10.1 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.8 18.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.8 21.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.8 9.8 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.7 32.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.7 27.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.7 10.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.7 20.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.7 6.9 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.7 12.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.7 9.3 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.6 10.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.6 44.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.6 7.9 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.5 6.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.5 15.3 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.5 6.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.5 12.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.5 20.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.5 1.9 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.5 6.1 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.5 16.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.5 7.8 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.5 7.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.4 15.2 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.4 27.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.4 35.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.4 4.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.4 5.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.4 2.3 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.4 7.8 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.4 10.9 REACTOME KINESINS Genes involved in Kinesins
0.3 4.5 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.3 6.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.3 11.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.3 8.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.3 7.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.3 3.7 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.3 14.3 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.3 5.1 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.3 15.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.3 12.7 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.3 15.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.3 6.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.3 13.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.3 3.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2 2.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2 24.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 3.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 5.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.2 7.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.2 7.1 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.2 1.6 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.2 7.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 3.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 5.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 0.9 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 2.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 0.9 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 0.8 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.4 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.1 3.2 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.1 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 6.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 4.4 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.1 0.9 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 3.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.6 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events