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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Nfatc1

Z-value: 1.09

Motif logo

Transcription factors associated with Nfatc1

Gene Symbol Gene ID Gene Info
ENSRNOG00000017146 nuclear factor of activated T-cells 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfatc1rn6_v1_chr18_-_77322690_773226900.702.2e-49Click!

Activity profile of Nfatc1 motif

Sorted Z-values of Nfatc1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_80796670 40.56 ENSRNOT00000010539
actin-binding Rho activating protein
chr9_+_14529218 35.56 ENSRNOT00000016893
apolipoprotein B mRNA editing enzyme catalytic subunit 2
chr11_+_35568182 29.69 ENSRNOT00000002259
potassium voltage-gated channel subfamily J member 15
chr3_+_14482388 28.93 ENSRNOT00000025857
gelsolin
chr7_+_38858062 27.18 ENSRNOT00000006234
keratocan
chr1_+_89008117 26.79 ENSRNOT00000028401
heat shock protein family B (small) member 6
chr18_-_77322690 24.35 ENSRNOT00000058382
nuclear factor of activated T-cells 1
chrX_-_31780425 23.76 ENSRNOT00000004693
ankyrin repeat and SOCS box-containing 9
chr8_-_114449956 22.61 ENSRNOT00000056414
collagen type VI alpha 6 chain
chr2_-_257484587 22.21 ENSRNOT00000083344
nexilin (F actin binding protein)
chr2_-_22744407 21.38 ENSRNOT00000073710
cardiomyopathy associated 5
chr5_-_60191941 21.16 ENSRNOT00000033373
paired box 5
chr2_+_11658568 21.07 ENSRNOT00000076408
ENSRNOT00000076416
ENSRNOT00000076992
ENSRNOT00000075931
ENSRNOT00000076136
ENSRNOT00000076481
ENSRNOT00000076084
ENSRNOT00000076230
ENSRNOT00000076710
ENSRNOT00000076239
myocyte enhancer factor 2C
chr13_+_98615287 20.87 ENSRNOT00000004032
inositol-trisphosphate 3-kinase B
chr1_+_198655742 20.86 ENSRNOT00000023944
myosin light chain, phosphorylatable, fast skeletal muscle
chr6_-_125723732 19.77 ENSRNOT00000084815
fibulin 5
chr6_-_125723944 19.03 ENSRNOT00000007004
fibulin 5
chr16_-_49574314 18.94 ENSRNOT00000017568
ENSRNOT00000085535
ENSRNOT00000017054
PDZ and LIM domain 3
chr7_+_120153184 18.55 ENSRNOT00000013538
galectin 1
chr7_-_98098268 18.05 ENSRNOT00000010361
F-box protein 32
chr13_+_50164563 17.80 ENSRNOT00000029533
lymphocyte transmembrane adaptor 1
chr1_-_237910012 17.38 ENSRNOT00000023664
annexin A1
chr1_+_18491384 17.07 ENSRNOT00000079138
ENSRNOT00000014917
laminin subunit alpha 2
chr7_-_81592206 16.81 ENSRNOT00000007979
angiopoietin 1
chr16_-_75309176 16.55 ENSRNOT00000018427
defensin beta 1
chr4_+_98337367 16.27 ENSRNOT00000042165

chr4_-_176922424 16.17 ENSRNOT00000055540
ATP binding cassette subfamily C member 9
chr2_-_251532312 16.12 ENSRNOT00000019501
cysteine-rich, angiogenic inducer, 61
chr3_-_71845232 15.97 ENSRNOT00000078645
calcitonin receptor like receptor
chr14_-_22890958 14.89 ENSRNOT00000031916
lymphocyte antigen 6B-like
chr4_+_153774486 14.88 ENSRNOT00000074096
tubulin, alpha 8
chr6_+_10348308 14.43 ENSRNOT00000034991
endothelial PAS domain protein 1
chr4_+_180291389 14.43 ENSRNOT00000002465
sarcospan
chr13_-_82005741 14.36 ENSRNOT00000076404
methyltransferase like 11B
chr16_+_6962722 14.07 ENSRNOT00000023330
musculoskeletal, embryonic nuclear protein 1
chr13_-_82006005 13.61 ENSRNOT00000039581
methyltransferase like 11B
chr13_+_90301006 13.55 ENSRNOT00000029315
SLAM family member 6
chr2_+_190007216 13.32 ENSRNOT00000015612
S100 calcium binding protein A6
chr5_+_144308611 13.17 ENSRNOT00000014388
collagen type VIII alpha 2 chain
chr3_+_97349454 13.14 ENSRNOT00000089524
doublecortin domain containing 5
chr17_-_31813716 13.12 ENSRNOT00000074147

chr4_+_169147243 13.08 ENSRNOT00000011580
epithelial membrane protein 1
chr4_+_169161585 12.92 ENSRNOT00000079785
epithelial membrane protein 1
chr14_+_82867946 12.79 ENSRNOT00000075130
spondin 2
chr1_-_25839198 12.73 ENSRNOT00000090388
ENSRNOT00000092757
ENSRNOT00000042072
triadin
chr2_+_189423559 12.57 ENSRNOT00000029076
tropomyosin 3
chr17_-_15511972 12.48 ENSRNOT00000074041
asporin-like 1
chr4_+_14109864 12.43 ENSRNOT00000076349
similar to fatty acid translocase/CD36
chr6_+_137063611 12.35 ENSRNOT00000017504
hypothetical protein LOC691485
chr11_-_73678984 11.89 ENSRNOT00000002355
family with sequence similarity 43, member A
chr8_-_84632817 11.78 ENSRNOT00000076942
muscular LMNA-interacting protein
chr16_+_81616604 11.76 ENSRNOT00000026392
ENSRNOT00000057740
ADP-ribosylhydrolase like 1
growth hormone regulated TBC protein 1
chr1_-_266914093 11.68 ENSRNOT00000027526
calcium homeostasis modulator 2
chr10_+_23661013 11.58 ENSRNOT00000076664
early B-cell factor 1
chr4_+_183656013 11.50 ENSRNOT00000055442
electron transfer flavoprotein beta subunit lysine methyltransferase
chr10_-_108321644 11.30 ENSRNOT00000075171
TBC1 domain family, member 16
chr15_+_32811135 11.27 ENSRNOT00000067689

chr11_-_76888178 11.21 ENSRNOT00000049841
osteocrin
chr10_-_88163712 11.19 ENSRNOT00000005382
ENSRNOT00000084493
keratin 17
chr19_+_568287 11.05 ENSRNOT00000016419
cadherin 16
chr6_-_143195143 10.92 ENSRNOT00000081337

chrX_-_38196060 10.87 ENSRNOT00000006741
ENSRNOT00000006438
SH3 domain-containing kinase-binding protein 1
chr17_-_15478343 10.86 ENSRNOT00000078029
osteomodulin
chr17_-_14637832 10.80 ENSRNOT00000074323
osteomodulin
chrX_-_31851715 10.76 ENSRNOT00000068601
vascular endothelial growth factor D
chr2_-_235177275 10.72 ENSRNOT00000093153
uncharacterized LOC103691699
chrX_+_65226748 10.33 ENSRNOT00000076181
moesin
chr17_-_81187739 10.04 ENSRNOT00000063911
3-hydroxyacyl-CoA dehydratase 1
chr10_-_88122233 10.00 ENSRNOT00000083895
ENSRNOT00000005285
keratin 14
chr1_+_218466289 9.95 ENSRNOT00000017948
MAS related GPR family member F
chr2_+_68820615 9.94 ENSRNOT00000087007
ENSRNOT00000089504
epidermal growth factor
chr11_+_42945084 9.80 ENSRNOT00000002292
crystallin beta-gamma domain containing 3
chr15_+_104026601 9.79 ENSRNOT00000013520
ENSRNOT00000083269
ENSRNOT00000093403
claudin 10
chr8_+_99880073 9.73 ENSRNOT00000010765
phospholipid scramblase 4
chr12_-_5685448 9.70 ENSRNOT00000077167
FRY microtubule binding protein
chr3_+_148541909 9.62 ENSRNOT00000012187
CCM2 like scaffolding protein
chr2_+_68821004 9.55 ENSRNOT00000083713
epidermal growth factor
chr3_+_19045214 9.40 ENSRNOT00000070878

chr13_+_27465930 9.37 ENSRNOT00000003314
serpin family B member 10
chr3_-_47025128 9.34 ENSRNOT00000011682
RNA binding motif, single stranded interacting protein 1
chr3_+_19495628 9.27 ENSRNOT00000077990
immunoglobulin kappa variable 4-57
chr11_-_60547201 9.21 ENSRNOT00000093151
B and T lymphocyte associated
chr4_-_113610243 9.16 ENSRNOT00000008813
hexokinase 2
chr2_+_150756185 9.06 ENSRNOT00000088461
ENSRNOT00000036808
muscleblind-like splicing regulator 1
chr5_-_24631679 9.04 ENSRNOT00000010846
ENSRNOT00000067129
epithelial splicing regulatory protein 1
chr13_+_90116843 8.91 ENSRNOT00000006306
Cd48 molecule
chr11_-_32550539 8.87 ENSRNOT00000002715
regulator of calcineurin 1
chr13_-_67688477 8.65 ENSRNOT00000068148
proteoglycan 4
chr11_+_71872830 8.62 ENSRNOT00000050364
negative regulator of reactive oxygen species
chr9_+_16702460 8.42 ENSRNOT00000061432
protein tyrosine kinase 7
chr4_-_103569159 8.41 ENSRNOT00000084036

chr4_-_103369224 8.35 ENSRNOT00000075709

chr6_-_143195445 8.30 ENSRNOT00000078672

chr14_-_72025137 8.26 ENSRNOT00000080604
C1q and tumor necrosis factor related protein 7
chr10_-_47997796 8.21 ENSRNOT00000078422
solute carrier family 5 member 10
chr1_+_266255797 8.19 ENSRNOT00000027047
tripartite motif-containing 8
chr13_+_50434702 8.10 ENSRNOT00000032244
SRY box 13
chr20_-_27657983 8.03 ENSRNOT00000057313
family with sequence similarity 26, member E
chr3_-_46942966 8.02 ENSRNOT00000087439
RNA binding motif, single stranded interacting protein 1
chr3_-_153246433 7.93 ENSRNOT00000067748
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
chr4_-_103145058 7.86 ENSRNOT00000073076

chr13_-_67819835 7.79 ENSRNOT00000093666
hemicentin 1
chr17_+_44763598 7.75 ENSRNOT00000079880
histone cluster 1, H3b
chr11_-_60546997 7.75 ENSRNOT00000083124
ENSRNOT00000050092
B and T lymphocyte associated
chr7_+_95074236 7.67 ENSRNOT00000067649
collagen type XIV alpha 1 chain
chr6_-_109935533 7.62 ENSRNOT00000013516
transforming growth factor, beta 3
chr9_-_115382445 7.56 ENSRNOT00000091316
protein tyrosine phosphatase, receptor type, M
chr18_-_6782757 7.55 ENSRNOT00000068150
aquaporin 4
chr13_-_83202864 7.53 ENSRNOT00000003976
X-C motif chemokine ligand 1
chr2_-_183031214 7.42 ENSRNOT00000013260
similar to RIKEN cDNA D930015E06
chr1_+_63842277 7.42 ENSRNOT00000087957
ENSRNOT00000080820
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3A
chr15_+_32828165 7.35 ENSRNOT00000060253

chr2_-_193330699 7.12 ENSRNOT00000012684
cysteine-rich C-terminal 1
chr3_+_116899878 7.09 ENSRNOT00000090802
ENSRNOT00000066101
semaphorin 6D
chr8_-_132919110 7.02 ENSRNOT00000008747
X-C motif chemokine receptor 1
chr7_-_96464049 7.01 ENSRNOT00000006517
hyaluronan synthase 2
chr9_-_88534710 6.92 ENSRNOT00000020880
transmembrane 4 L six family member 20
chr13_+_50434886 6.90 ENSRNOT00000076857
SRY box 13
chr18_-_6782996 6.77 ENSRNOT00000090320
aquaporin 4
chr3_+_28627084 6.76 ENSRNOT00000049884
Rho GTPase activating protein 15
chr8_+_2604962 6.72 ENSRNOT00000009993
caspase 1
chr17_+_5281727 6.58 ENSRNOT00000024781
iron-sulfur cluster assembly 1
chr1_-_24190896 6.57 ENSRNOT00000016121
serum/glucocorticoid regulated kinase 1
chr8_-_18508971 6.48 ENSRNOT00000061339
mucin 16, cell surface associated
chr1_-_77808462 6.47 ENSRNOT00000078917
ENSRNOT00000080422
selenoprotein W-like
chr18_+_30562178 6.38 ENSRNOT00000040998
protocadherin beta-16-like
chr1_+_213070528 6.29 ENSRNOT00000051727
olfactory receptor 302
chr12_-_38916237 6.26 ENSRNOT00000074517
transmembrane protein 120B
chr18_+_30826260 6.22 ENSRNOT00000065235
protocadherin gamma subfamily B, 1
chrX_-_29648359 6.14 ENSRNOT00000086721
ENSRNOT00000006777
glycoprotein m6b
chr10_+_83655460 6.12 ENSRNOT00000008011
G protein subunit gamma transducin 2
chr3_-_171342646 6.01 ENSRNOT00000071853
prostate transmembrane protein, androgen induced 1
chr1_-_77535681 5.91 ENSRNOT00000018559
selenoprotein W
chr4_-_17594598 5.90 ENSRNOT00000008936
semaphorin 3E
chr18_+_65155685 5.87 ENSRNOT00000081797
transcription factor 4
chr6_-_142178771 5.86 ENSRNOT00000071577
immunoglobulin heavy variable V12-3
chr1_+_164502389 5.74 ENSRNOT00000043554
arrestin, beta 1
chr4_+_99168248 5.69 ENSRNOT00000058186
uncharacterized LOC102552663
chr6_+_8284878 5.69 ENSRNOT00000009581
solute carrier family 3 member 1
chr16_+_74810938 5.62 ENSRNOT00000058091
NIMA-related kinase 5
chr1_-_8751198 5.61 ENSRNOT00000030511
adhesion G protein-coupled receptor G6
chr18_+_30496318 5.51 ENSRNOT00000027179
protocadherin beta 11
chr4_-_157433467 5.50 ENSRNOT00000028965
lymphocyte activating 3
chr5_-_58183017 5.47 ENSRNOT00000020982
C-C motif chemokine ligand 19
chr8_-_23146689 5.47 ENSRNOT00000092200
acid phosphatase 5, tartrate resistant
chr3_-_48536235 5.46 ENSRNOT00000083536
fibroblast activation protein, alpha
chr8_-_39551700 5.46 ENSRNOT00000091894
ENSRNOT00000076025
PBX/knotted 1 homeobox 2
chr5_+_133864798 5.44 ENSRNOT00000091977
TAL bHLH transcription factor 1, erythroid differentiation factor
chr8_+_116324040 5.42 ENSRNOT00000081353
hyaluronoglucosaminidase 2
chr7_-_142062870 5.40 ENSRNOT00000026531
solute carrier family 11 member 2
chr10_-_46206135 5.36 ENSRNOT00000091471
COP9 signalosome subunit 3
chr2_-_208215187 5.31 ENSRNOT00000047836
RAP1A, member of RAS oncogene family
chr13_+_92241306 5.23 ENSRNOT00000004677
olfactory receptor 1595
chr4_+_102262007 5.22 ENSRNOT00000079328

chr14_-_60276794 5.21 ENSRNOT00000048509
solute carrier family 34 member 2
chr14_-_84170835 5.13 ENSRNOT00000005646
solute carrier family 35, member E4
chr4_+_181055662 5.10 ENSRNOT00000086813
serine/threonine kinase 38 like
chr3_-_64024205 5.09 ENSRNOT00000037015
coiled-coil domain containing 141
chr3_+_19128400 5.01 ENSRNOT00000074272

chr1_+_88885937 4.97 ENSRNOT00000029719
NFKB inhibitor delta
chr14_-_44225713 4.94 ENSRNOT00000049161
similar to ribosomal protein L14
chr4_-_29778039 4.93 ENSRNOT00000074177
sarcoglycan, epsilon
chr13_-_68360664 4.92 ENSRNOT00000030971
hemicentin 1
chr8_-_48850671 4.92 ENSRNOT00000016580
C-X-C motif chemokine receptor 5
chr16_-_3912148 4.91 ENSRNOT00000014941
annexin A11
chr14_-_81053905 4.89 ENSRNOT00000045068
ENSRNOT00000040215
regulator of G-protein signaling 12
chr3_+_140024043 4.87 ENSRNOT00000086409
Ras and Rab interactor 2
chr4_+_129574264 4.67 ENSRNOT00000010185
ADP-ribosylation factor like GTPase 6 interacting protein 5
chr16_+_75572070 4.61 ENSRNOT00000043486
defensin beta 52
chrX_+_18489597 4.59 ENSRNOT00000059744
similar to potassium channel tetramerisation domain containing 12b
chr1_-_116153722 4.58 ENSRNOT00000041605
formyl peptide receptor 3
chr15_+_4285052 4.57 ENSRNOT00000035345
cilia and flagella associated protein 70
chr18_+_30864216 4.54 ENSRNOT00000027015
protocadherin gamma subfamily A, 7
chrX_-_25590048 4.51 ENSRNOT00000004873
midline 1
chr2_+_216863428 4.47 ENSRNOT00000068413
collagen type XI alpha 1 chain
chr18_+_86299463 4.44 ENSRNOT00000058152
CD226 molecule
chr7_-_142063212 4.40 ENSRNOT00000089912
solute carrier family 11 member 2
chr1_-_228753422 4.29 ENSRNOT00000028626
deltex E3 ubiquitin ligase 4
chr5_-_99033107 4.29 ENSRNOT00000041306
heat shock protein family A (Hsp70) member 8
chr16_-_74020437 4.23 ENSRNOT00000037389
lysine acetyltransferase 6A
chr18_+_30890869 4.22 ENSRNOT00000060466
protocadherin gamma subfamily B, 6
chr10_+_34489940 4.18 ENSRNOT00000085975
zinc finger protein 62
chr9_+_79659251 4.17 ENSRNOT00000021656
X-ray repair cross complementing 5
chr2_+_165601007 4.08 ENSRNOT00000013931
structural maintenance of chromosomes 4
chr5_-_147761983 4.05 ENSRNOT00000012936
LCK proto-oncogene, Src family tyrosine kinase
chr14_-_84170301 4.05 ENSRNOT00000080413
solute carrier family 35, member E4
chr2_+_186555632 4.00 ENSRNOT00000052347
Fc receptor-like 1
chr6_+_115170865 3.98 ENSRNOT00000005671
thyroid stimulating hormone receptor
chr18_-_74542077 3.98 ENSRNOT00000078519
solute carrier family 14 member 2
chrX_-_104984341 3.93 ENSRNOT00000077996
XK related, X-linked
chr13_-_77896697 3.88 ENSRNOT00000003452
tenascin N
chr12_+_23544287 3.74 ENSRNOT00000001938
ORAI calcium release-activated calcium modulator 2
chr16_-_81028656 3.71 ENSRNOT00000091296
defective in cullin neddylation 1 domain containing 2
chr9_-_61810417 3.71 ENSRNOT00000020910
raftlin family member 2
chr3_+_151126591 3.70 ENSRNOT00000025859
myosin heavy chain 7B
chr7_+_141237768 3.69 ENSRNOT00000091717
aquaporin 2
chr7_-_97071968 3.67 ENSRNOT00000006596
solute carrier family 22 (organic cation transporter), member 22
chr14_+_73674753 3.63 ENSRNOT00000040676
similar to High mobility group protein 2 (HMG-2)
chr18_+_28409955 3.62 ENSRNOT00000026989
poly(A) binding protein interacting protein 2
chr4_+_56337695 3.62 ENSRNOT00000071926
leptin

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfatc1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
9.6 28.9 GO:1903923 protein processing in phagocytic vesicle(GO:1900756) regulation of establishment of T cell polarity(GO:1903903) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
9.3 28.0 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
8.9 35.6 GO:0016554 cytidine to uridine editing(GO:0016554)
6.1 24.3 GO:0002337 B-1a B cell differentiation(GO:0002337)
5.8 11.5 GO:1904732 regulation of electron carrier activity(GO:1904732)
5.6 16.8 GO:0048014 Tie signaling pathway(GO:0048014)
5.3 21.1 GO:2001013 positive regulation of macrophage apoptotic process(GO:2000111) epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
4.6 22.8 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
4.2 12.7 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
4.2 20.9 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
4.1 16.6 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
3.9 38.8 GO:0048251 elastic fiber assembly(GO:0048251)
3.7 11.2 GO:1903860 negative regulation of dendrite extension(GO:1903860)
3.7 18.5 GO:0002317 plasma cell differentiation(GO:0002317)
3.6 3.6 GO:0071298 cellular response to L-ascorbic acid(GO:0071298)
3.6 18.0 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
3.6 14.4 GO:0048625 myoblast fate commitment(GO:0048625)
3.6 10.8 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
3.6 14.3 GO:0060354 negative regulation of cell adhesion molecule production(GO:0060354)
3.6 21.4 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
3.5 14.1 GO:1902730 positive regulation of proteoglycan biosynthetic process(GO:1902730)
3.3 10.0 GO:0071529 cementum mineralization(GO:0071529)
3.3 9.8 GO:0035444 nickel cation transport(GO:0015675) vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) nickel cation transmembrane transport(GO:0035444)
3.2 16.2 GO:0060327 cytoplasmic actin-based contraction involved in cell motility(GO:0060327)
2.9 11.8 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
2.8 19.5 GO:0007262 STAT protein import into nucleus(GO:0007262)
2.7 16.1 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
2.6 12.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
2.5 7.6 GO:0003032 detection of oxygen(GO:0003032) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
2.5 15.1 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
2.5 7.5 GO:0071661 immunoglobulin production in mucosal tissue(GO:0002426) T-helper 1 cell activation(GO:0035711) granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663) regulation of thymocyte migration(GO:2000410) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
2.5 7.4 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
2.4 9.7 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
2.3 9.2 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
2.1 19.1 GO:0061303 cornea development in camera-type eye(GO:0061303)
2.1 12.4 GO:0070295 renal water absorption(GO:0070295)
2.1 10.3 GO:1902966 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
2.0 6.1 GO:0061740 protein targeting to lysosome involved in chaperone-mediated autophagy(GO:0061740) regulation of lysosomal membrane permeability(GO:0097213) positive regulation of lysosomal membrane permeability(GO:0097214)
2.0 7.9 GO:0046061 dATP catabolic process(GO:0046061)
2.0 21.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
1.8 3.7 GO:0015793 glycerol transport(GO:0015793)
1.8 5.5 GO:0097325 melanocyte proliferation(GO:0097325)
1.8 5.4 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)
1.8 10.8 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
1.7 17.0 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
1.7 6.7 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
1.7 10.0 GO:0045110 intermediate filament bundle assembly(GO:0045110)
1.7 5.0 GO:2000399 negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of thymocyte aggregation(GO:2000399)
1.6 4.9 GO:0023021 termination of signal transduction(GO:0023021)
1.6 6.4 GO:0002036 regulation of L-glutamate transport(GO:0002036)
1.6 3.1 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
1.6 17.1 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
1.5 46.3 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
1.5 23.1 GO:0032060 bleb assembly(GO:0032060)
1.5 21.4 GO:0021670 lateral ventricle development(GO:0021670)
1.5 4.4 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
1.4 13.6 GO:0001787 natural killer cell proliferation(GO:0001787)
1.3 4.0 GO:1905225 response to thyrotropin-releasing hormone(GO:1905225)
1.2 6.1 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.2 1.2 GO:1903895 negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
1.2 2.3 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
1.1 16.0 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
1.1 2.3 GO:0072237 metanephric proximal tubule development(GO:0072237)
1.1 11.2 GO:0051798 positive regulation of hair follicle development(GO:0051798)
1.1 8.9 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
1.1 3.3 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
1.1 5.5 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
1.1 3.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
1.1 5.3 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
1.0 4.2 GO:1904430 negative regulation of t-circle formation(GO:1904430)
1.0 3.0 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191) regulation of osteoclast proliferation(GO:0090289)
1.0 6.0 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
1.0 3.9 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
1.0 29.7 GO:0010107 potassium ion import(GO:0010107)
0.9 6.6 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.9 8.4 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.9 3.7 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
0.9 5.5 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.9 2.7 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.8 26.8 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.8 4.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.8 2.4 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.8 4.0 GO:0071918 urea transmembrane transport(GO:0071918)
0.8 2.3 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210) negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.8 6.2 GO:0061193 taste bud development(GO:0061193)
0.7 5.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.7 8.9 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.7 9.7 GO:0017121 phospholipid scrambling(GO:0017121)
0.7 8.9 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.7 17.8 GO:0048305 inactivation of MAPK activity(GO:0000188) immunoglobulin secretion(GO:0048305)
0.6 4.5 GO:0035989 tendon development(GO:0035989)
0.6 1.9 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.6 5.6 GO:0060347 heart trabecula formation(GO:0060347)
0.6 3.7 GO:0033227 dsRNA transport(GO:0033227)
0.6 11.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.6 5.9 GO:0042118 endothelial cell activation(GO:0042118)
0.6 2.9 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.6 1.1 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.6 2.8 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.5 7.7 GO:0061050 regulation of cell growth involved in cardiac muscle cell development(GO:0061050)
0.5 2.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.5 1.6 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.5 11.5 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.5 4.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.5 5.4 GO:0000338 protein deneddylation(GO:0000338)
0.5 3.4 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.4 1.3 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.4 3.5 GO:1902969 mitotic DNA replication(GO:1902969)
0.4 8.2 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.4 3.4 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.4 4.6 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.4 2.4 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.4 1.6 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.4 1.5 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.4 1.1 GO:0018343 protein farnesylation(GO:0018343)
0.4 9.4 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.3 2.9 GO:0060613 fat pad development(GO:0060613)
0.3 13.7 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.3 7.6 GO:0010842 retina layer formation(GO:0010842)
0.3 0.9 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.3 2.9 GO:0016266 O-glycan processing(GO:0016266)
0.3 4.9 GO:0048535 lymph node development(GO:0048535)
0.3 2.9 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.3 7.1 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.3 5.9 GO:0010269 response to selenium ion(GO:0010269)
0.3 1.1 GO:0007296 vitellogenesis(GO:0007296)
0.3 8.2 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.2 1.2 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.2 4.2 GO:0035909 aorta morphogenesis(GO:0035909)
0.2 0.9 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.2 2.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 5.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.2 13.4 GO:0030500 regulation of bone mineralization(GO:0030500)
0.2 3.7 GO:0002115 store-operated calcium entry(GO:0002115)
0.2 0.8 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.2 6.7 GO:0001569 patterning of blood vessels(GO:0001569)
0.2 5.9 GO:0001919 regulation of receptor recycling(GO:0001919)
0.2 0.7 GO:2000173 negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.2 8.6 GO:0006801 superoxide metabolic process(GO:0006801)
0.2 0.4 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.2 3.7 GO:0045116 protein neddylation(GO:0045116)
0.2 5.1 GO:0051642 centrosome localization(GO:0051642)
0.2 2.6 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.2 1.3 GO:0002329 pre-B cell differentiation(GO:0002329)
0.2 0.8 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.2 13.2 GO:0048593 camera-type eye morphogenesis(GO:0048593)
0.1 3.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 1.9 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 0.7 GO:0048539 bone marrow development(GO:0048539)
0.1 2.2 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.1 4.2 GO:1900271 regulation of long-term synaptic potentiation(GO:1900271)
0.1 1.1 GO:0014894 response to stimulus involved in regulation of muscle adaptation(GO:0014874) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 25.9 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.1 7.0 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 2.2 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 24.5 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.1 2.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 2.9 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 3.2 GO:0051155 positive regulation of striated muscle cell differentiation(GO:0051155)
0.1 8.9 GO:0045576 mast cell activation(GO:0045576)
0.1 3.1 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.1 3.0 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.1 2.6 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 0.3 GO:0061295 pronephric nephron tubule development(GO:0039020) regulation of endodermal cell fate specification(GO:0042663) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) regulation of branch elongation involved in ureteric bud branching(GO:0072095) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.1 1.4 GO:0008298 intracellular mRNA localization(GO:0008298)
0.1 2.8 GO:0051057 positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.1 1.7 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 11.0 GO:0008360 regulation of cell shape(GO:0008360)
0.1 1.5 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.8 GO:0051895 platelet-derived growth factor receptor-beta signaling pathway(GO:0035791) negative regulation of focal adhesion assembly(GO:0051895) positive regulation of extracellular matrix disassembly(GO:0090091) negative regulation of adherens junction organization(GO:1903392) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.4 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 1.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 1.0 GO:0007320 insemination(GO:0007320)
0.1 1.2 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.1 1.2 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 0.6 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.2 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 0.8 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.7 GO:0055070 copper ion homeostasis(GO:0055070)
0.1 1.9 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.7 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 1.6 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.9 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.5 GO:0007000 nucleolus organization(GO:0007000)
0.0 2.4 GO:0032543 mitochondrial translation(GO:0032543)
0.0 1.5 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.3 GO:0045657 apoptotic chromosome condensation(GO:0030263) positive regulation of monocyte differentiation(GO:0045657)
0.0 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 5.4 GO:0006909 phagocytosis(GO:0006909)
0.0 1.7 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 2.3 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.9 GO:0018149 peptide cross-linking(GO:0018149)
0.0 2.2 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 1.3 GO:0048278 vesicle docking(GO:0048278)
0.0 0.8 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 3.5 GO:0045444 fat cell differentiation(GO:0045444)
0.0 0.9 GO:0007140 male meiosis(GO:0007140)
0.0 0.9 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.3 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.2 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.6 GO:0001824 blastocyst development(GO:0001824)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
7.8 38.8 GO:0071953 elastic fiber(GO:0071953)
4.8 28.9 GO:0030478 actin cap(GO:0030478)
4.2 12.7 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
4.0 16.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
3.7 3.7 GO:0097512 cardiac myofibril(GO:0097512)
3.3 9.8 GO:0070826 paraferritin complex(GO:0070826)
2.0 6.1 GO:1990836 lysosomal matrix(GO:1990836)
1.9 17.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
1.8 12.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
1.5 4.5 GO:0005592 collagen type XI trimer(GO:0005592)
1.3 6.7 GO:0072557 IPAF inflammasome complex(GO:0072557) NLRP1 inflammasome complex(GO:0072558) AIM2 inflammasome complex(GO:0097169)
1.2 16.1 GO:0031143 pseudopodium(GO:0031143)
1.2 3.5 GO:0000811 GINS complex(GO:0000811)
1.1 20.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
1.0 4.2 GO:0043564 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) Ku70:Ku80 complex(GO:0043564)
0.8 30.5 GO:0046930 pore complex(GO:0046930)
0.8 5.5 GO:0071438 invadopodium membrane(GO:0071438)
0.7 2.7 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306)
0.6 16.6 GO:0097225 sperm midpiece(GO:0097225)
0.6 21.4 GO:0005581 collagen trimer(GO:0005581)
0.6 2.3 GO:0002079 inner acrosomal membrane(GO:0002079)
0.5 2.2 GO:0097149 centralspindlin complex(GO:0097149)
0.5 20.0 GO:0043034 costamere(GO:0043034)
0.5 17.1 GO:0005605 basal lamina(GO:0005605)
0.5 111.1 GO:0030017 sarcomere(GO:0030017)
0.5 4.1 GO:0000796 condensin complex(GO:0000796)
0.5 3.4 GO:0031415 NatA complex(GO:0031415)
0.5 8.3 GO:0030061 mitochondrial crista(GO:0030061)
0.5 2.3 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.5 9.0 GO:0005614 interstitial matrix(GO:0005614)
0.4 3.5 GO:0005869 dynactin complex(GO:0005869)
0.4 4.2 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.4 5.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 4.9 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.3 5.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.3 8.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.3 102.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.3 21.5 GO:0045095 keratin filament(GO:0045095)
0.3 0.8 GO:1990032 climbing fiber(GO:0044301) parallel fiber(GO:1990032)
0.2 0.7 GO:1990879 CST complex(GO:1990879)
0.2 5.2 GO:0031528 microvillus membrane(GO:0031528)
0.2 11.8 GO:0016459 myosin complex(GO:0016459)
0.2 1.9 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.2 6.1 GO:0000242 pericentriolar material(GO:0000242)
0.2 21.6 GO:0016605 PML body(GO:0016605)
0.2 3.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 0.8 GO:0005955 calcineurin complex(GO:0005955)
0.2 9.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.2 4.9 GO:0097440 apical dendrite(GO:0097440)
0.2 2.0 GO:0031932 TORC2 complex(GO:0031932)
0.1 5.4 GO:0008180 COP9 signalosome(GO:0008180)
0.1 47.1 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 1.7 GO:0042611 MHC protein complex(GO:0042611)
0.1 7.5 GO:0031901 early endosome membrane(GO:0031901)
0.1 5.5 GO:0045171 intercellular bridge(GO:0045171)
0.1 35.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 2.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 16.7 GO:0001650 fibrillar center(GO:0001650)
0.1 0.8 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 5.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 5.7 GO:0031526 brush border membrane(GO:0031526)
0.1 0.3 GO:0061574 ASAP complex(GO:0061574)
0.1 0.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 1.2 GO:0017119 Golgi transport complex(GO:0017119)
0.1 3.1 GO:0031225 anchored component of membrane(GO:0031225)
0.1 7.8 GO:0044815 nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.1 1.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 5.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 2.0 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 37.6 GO:0016604 nuclear body(GO:0016604)
0.1 2.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 2.2 GO:0031201 SNARE complex(GO:0031201)
0.0 0.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 4.9 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 3.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 8.8 GO:0005938 cell cortex(GO:0005938)
0.0 0.9 GO:0001533 cornified envelope(GO:0001533)
0.0 2.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 11.2 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.7 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.8 GO:0032432 actin filament bundle(GO:0032432)
0.0 1.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 7.4 GO:0005925 focal adhesion(GO:0005925)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 4.5 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.5 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.8 GO:0005882 intermediate filament(GO:0005882)
0.0 0.4 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
9.3 28.0 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
7.2 28.9 GO:0045159 myosin II binding(GO:0045159)
6.1 24.3 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
5.9 35.6 GO:0004126 cytidine deaminase activity(GO:0004126)
5.4 16.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
5.3 16.0 GO:0001605 adrenomedullin receptor activity(GO:0001605)
4.1 16.6 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
3.5 17.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
3.3 10.0 GO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
3.3 9.8 GO:0015100 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) nickel cation transmembrane transporter activity(GO:0015099) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) chromium ion transmembrane transporter activity(GO:0070835)
3.1 18.5 GO:0048030 disaccharide binding(GO:0048030)
3.0 9.1 GO:0001069 regulatory region RNA binding(GO:0001069)
2.8 16.7 GO:0042289 MHC class II protein binding(GO:0042289)
2.3 20.9 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
2.2 8.9 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
2.1 8.4 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
2.0 10.0 GO:1990254 keratin filament binding(GO:1990254)
2.0 5.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.9 5.7 GO:0031893 follicle-stimulating hormone receptor binding(GO:0031762) vasopressin receptor binding(GO:0031893)
1.8 5.5 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
1.8 5.4 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
1.7 15.2 GO:0050897 cobalt ion binding(GO:0050897)
1.6 14.6 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
1.6 74.6 GO:0008307 structural constituent of muscle(GO:0008307)
1.5 9.2 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
1.5 7.6 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
1.4 21.1 GO:0035198 miRNA binding(GO:0035198)
1.4 7.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
1.4 19.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
1.3 30.5 GO:0015288 porin activity(GO:0015288)
1.3 29.7 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
1.3 8.9 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
1.3 26.8 GO:0005212 structural constituent of eye lens(GO:0005212)
1.1 3.3 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
1.1 18.2 GO:0044548 S100 protein binding(GO:0044548)
1.1 13.8 GO:0042609 CD4 receptor binding(GO:0042609)
1.0 5.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
1.0 13.0 GO:0030215 semaphorin receptor binding(GO:0030215)
1.0 7.9 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
0.9 8.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.8 3.4 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.8 7.6 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.8 3.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.8 8.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.8 6.2 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.8 4.6 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.8 6.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.8 2.3 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.6 16.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.6 4.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.6 5.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.6 11.6 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.6 3.4 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.6 4.0 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.5 4.9 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.5 6.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.5 12.8 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.5 11.8 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.4 17.8 GO:0042169 SH2 domain binding(GO:0042169)
0.4 48.1 GO:0005178 integrin binding(GO:0005178)
0.4 2.9 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.4 8.6 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.4 7.0 GO:0004950 chemokine receptor activity(GO:0004950)
0.4 7.4 GO:0008199 ferric iron binding(GO:0008199)
0.4 2.8 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.3 1.3 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.3 1.9 GO:1990226 histone methyltransferase binding(GO:1990226)
0.3 2.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.3 3.7 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.3 18.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.3 4.0 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.3 6.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.3 5.6 GO:0043236 laminin binding(GO:0043236)
0.3 1.5 GO:0045545 syndecan binding(GO:0045545)
0.3 6.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.3 2.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 3.5 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.2 3.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 6.3 GO:0030371 translation repressor activity(GO:0030371)
0.2 1.2 GO:0089720 caspase binding(GO:0089720)
0.2 1.1 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.2 3.7 GO:0097602 cullin family protein binding(GO:0097602)
0.2 3.2 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.2 3.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 11.5 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.2 0.9 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 3.6 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.2 2.2 GO:0016208 AMP binding(GO:0016208)
0.2 1.8 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.2 2.9 GO:0070628 proteasome binding(GO:0070628)
0.1 2.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 11.0 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 5.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 3.5 GO:0070840 dynein complex binding(GO:0070840)
0.1 2.3 GO:0001848 complement binding(GO:0001848)
0.1 5.9 GO:0070888 E-box binding(GO:0070888)
0.1 3.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 1.0 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.8 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 9.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 2.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 1.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.7 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 0.8 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.1 4.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 11.3 GO:0044325 ion channel binding(GO:0044325)
0.1 4.2 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 1.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 2.2 GO:0043531 ADP binding(GO:0043531)
0.1 0.5 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 6.2 GO:0003823 antigen binding(GO:0003823)
0.1 2.3 GO:0050699 WW domain binding(GO:0050699)
0.1 0.6 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 1.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.2 GO:0043394 proteoglycan binding(GO:0043394)
0.1 5.6 GO:0016209 antioxidant activity(GO:0016209)
0.1 22.1 GO:0003779 actin binding(GO:0003779)
0.1 2.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 2.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 2.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 8.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 4.7 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.8 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 14.5 GO:0005198 structural molecule activity(GO:0005198)
0.0 1.1 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 2.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.3 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.3 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.7 GO:0005507 copper ion binding(GO:0005507)
0.0 0.7 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 3.5 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 20.9 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
1.1 46.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
1.0 52.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
1.0 32.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
1.0 28.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
1.0 19.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.9 29.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.9 32.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.8 26.9 NABA COLLAGENS Genes encoding collagen proteins
0.7 26.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.7 6.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.6 24.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.6 19.4 PID RAS PATHWAY Regulation of Ras family activation
0.5 28.5 PID SHP2 PATHWAY SHP2 signaling
0.4 31.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.4 12.0 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.4 5.8 PID NECTIN PATHWAY Nectin adhesion pathway
0.4 53.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3 14.6 PID FOXO PATHWAY FoxO family signaling
0.3 29.6 PID CMYB PATHWAY C-MYB transcription factor network
0.3 1.5 PID IL5 PATHWAY IL5-mediated signaling events
0.3 5.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.3 1.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.3 15.5 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.3 7.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.3 12.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 2.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.2 4.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.2 6.1 PID CONE PATHWAY Visual signal transduction: Cones
0.2 2.7 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.2 5.1 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.2 26.4 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.1 2.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 3.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 4.0 PID ARF6 PATHWAY Arf6 signaling events
0.1 4.5 PID RHOA PATHWAY RhoA signaling pathway
0.1 1.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 4.1 PID AURORA B PATHWAY Aurora B signaling
0.1 4.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 2.8 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.5 PID P53 REGULATION PATHWAY p53 pathway
0.0 2.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.6 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 16.6 REACTOME BETA DEFENSINS Genes involved in Beta defensins
2.7 38.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
1.5 18.0 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
1.4 52.0 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
1.1 31.5 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
1.0 28.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.9 16.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.8 14.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.8 27.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.7 13.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.6 10.8 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.6 11.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.6 6.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.5 25.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.5 4.1 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.5 12.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.4 6.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.4 4.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.4 8.0 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.4 24.1 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.4 4.0 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.3 10.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.3 3.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.3 5.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.3 7.8 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.3 17.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.3 3.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.3 2.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.3 15.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.3 3.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 6.0 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.2 2.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 16.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.2 9.2 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.2 2.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 4.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 2.9 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 3.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 6.1 REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism
0.1 1.9 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 2.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 2.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 24.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 7.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 4.1 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 7.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 5.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 11.1 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 6.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 2.8 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.6 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 4.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 1.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.0 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis