Project
GSE53960: rat RNA-Seq transcriptomic Bodymap
Navigation
Downloads
Results for Nfatc1
Z-value: 1.09
Motif logo
Transcription factors associated with Nfatc1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Nfatc1 | rn6_v1_chr18_-_77322690_77322690 | 0.70 | 2.2e-49 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_-_80796670 Show fit | 40.56 |
ENSRNOT00000010539
|
actin-binding Rho activating protein |
|
| chr9_+_14529218 Show fit | 35.56 |
ENSRNOT00000016893
|
apolipoprotein B mRNA editing enzyme catalytic subunit 2 |
|
| chr11_+_35568182 Show fit | 29.69 |
ENSRNOT00000002259
|
potassium voltage-gated channel subfamily J member 15 |
|
| chr3_+_14482388 Show fit | 28.93 |
ENSRNOT00000025857
|
gelsolin |
|
| chr7_+_38858062 Show fit | 27.18 |
ENSRNOT00000006234
|
keratocan |
|
| chr1_+_89008117 Show fit | 26.79 |
ENSRNOT00000028401
|
heat shock protein family B (small) member 6 |
|
| chr18_-_77322690 Show fit | 24.35 |
ENSRNOT00000058382
|
nuclear factor of activated T-cells 1 |
|
| chrX_-_31780425 Show fit | 23.76 |
ENSRNOT00000004693
|
ankyrin repeat and SOCS box-containing 9 |
|
| chr8_-_114449956 Show fit | 22.61 |
ENSRNOT00000056414
|
collagen type VI alpha 6 chain |
|
| chr2_-_257484587 Show fit | 22.21 |
ENSRNOT00000083344
|
nexilin (F actin binding protein) |
Network of associatons between targets according to the STRING database.
First level regulatory network of Nfatc1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 46.3 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
| 3.9 | 38.8 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 8.9 | 35.6 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 1.0 | 29.7 | GO:0010107 | potassium ion import(GO:0010107) |
| 9.6 | 28.9 | GO:1903923 | protein processing in phagocytic vesicle(GO:1900756) regulation of establishment of T cell polarity(GO:1903903) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923) |
| 9.3 | 28.0 | GO:0006480 | N-terminal protein amino acid methylation(GO:0006480) |
| 0.8 | 26.8 | GO:0010667 | negative regulation of cardiac muscle cell apoptotic process(GO:0010667) |
| 0.1 | 25.9 | GO:0007519 | skeletal muscle tissue development(GO:0007519) |
| 0.1 | 24.5 | GO:0045732 | positive regulation of protein catabolic process(GO:0045732) |
| 6.1 | 24.3 | GO:0002337 | B-1a B cell differentiation(GO:0002337) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 111.1 | GO:0030017 | sarcomere(GO:0030017) |
| 0.3 | 102.4 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.1 | 47.1 | GO:0098857 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 7.8 | 38.8 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.1 | 37.6 | GO:0016604 | nuclear body(GO:0016604) |
| 0.1 | 35.3 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.8 | 30.5 | GO:0046930 | pore complex(GO:0046930) |
| 4.8 | 28.9 | GO:0030478 | actin cap(GO:0030478) |
| 0.2 | 21.6 | GO:0016605 | PML body(GO:0016605) |
| 0.3 | 21.5 | GO:0045095 | keratin filament(GO:0045095) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 74.6 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.4 | 48.1 | GO:0005178 | integrin binding(GO:0005178) |
| 5.9 | 35.6 | GO:0004126 | cytidine deaminase activity(GO:0004126) |
| 1.3 | 30.5 | GO:0015288 | porin activity(GO:0015288) |
| 1.3 | 29.7 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
| 7.2 | 28.9 | GO:0045159 | myosin II binding(GO:0045159) |
| 9.3 | 28.0 | GO:0071885 | N-terminal protein N-methyltransferase activity(GO:0071885) |
| 1.3 | 26.8 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 6.1 | 24.3 | GO:0001225 | RNA polymerase II transcription coactivator binding(GO:0001225) |
| 0.1 | 22.1 | GO:0003779 | actin binding(GO:0003779) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 53.1 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 1.0 | 52.4 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 1.1 | 46.7 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.9 | 32.7 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 1.0 | 32.1 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.4 | 31.2 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.3 | 29.6 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.9 | 29.1 | PID AVB3 OPN PATHWAY | Osteopontin-mediated events |
| 1.0 | 28.9 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.5 | 28.5 | PID SHP2 PATHWAY | SHP2 signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 52.0 | REACTOME INWARDLY RECTIFYING K CHANNELS | Genes involved in Inwardly rectifying K+ channels |
| 2.7 | 38.0 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 1.1 | 31.5 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 1.0 | 28.9 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.8 | 27.4 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.5 | 25.0 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.1 | 24.2 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.4 | 24.1 | REACTOME COSTIMULATION BY THE CD28 FAMILY | Genes involved in Costimulation by the CD28 family |
| 1.5 | 18.0 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.3 | 17.2 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |