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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Neurog2

Z-value: 0.75

Motif logo

Transcription factors associated with Neurog2

Gene Symbol Gene ID Gene Info
ENSRNOG00000010972 neurogenin 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Neurog2rn6_v1_chr2_+_231962517_231962517-0.172.6e-03Click!

Activity profile of Neurog2 motif

Sorted Z-values of Neurog2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_128003418 45.35 ENSRNOT00000013896
serine (or cysteine) proteinase inhibitor, clade A, member 3C
chr6_+_128048099 38.08 ENSRNOT00000084685
ENSRNOT00000087017
Ab1-233
chr1_+_148240504 27.80 ENSRNOT00000085373
Cytochrome P450, family 2, subfamily c, polypeptide 7-like
chr15_+_28028521 26.13 ENSRNOT00000089631

chr19_+_42097995 25.00 ENSRNOT00000020197
haptoglobin
chr5_-_78985990 24.82 ENSRNOT00000009248
alpha-1-microglobulin/bikunin precursor
chr4_-_31730386 23.81 ENSRNOT00000013817
solute carrier family 25 member 13
chr3_-_101474890 23.16 ENSRNOT00000091869
gamma-butyrobetaine hydroxylase 1
chr7_+_28414350 21.05 ENSRNOT00000085680
insulin-like growth factor 1
chr8_-_111777602 20.99 ENSRNOT00000052317
ENSRNOT00000083855
similar to RIKEN cDNA 1300017J02
chr7_-_2431197 19.88 ENSRNOT00000003498
hydroxysteroid (17-beta) dehydrogenase 6
chr19_-_22632071 18.45 ENSRNOT00000077275
glutamic--pyruvic transaminase 2
chr1_+_145715969 16.55 ENSRNOT00000037996
transmembrane channel-like 3
chr11_-_88972176 16.22 ENSRNOT00000002498
plakophilin 2
chr1_+_72810545 16.02 ENSRNOT00000092117
protein tyrosine phosphatase, receptor type, H
chr17_+_30556884 15.87 ENSRNOT00000080929
ENSRNOT00000022022
enoyl-CoA delta isomerase 2
chr17_+_69468427 15.69 ENSRNOT00000058413
similar to 20-alpha-hydroxysteroid dehydrogenase
chr4_+_122365093 14.93 ENSRNOT00000024011
Kruppel-like factor 15
chr1_-_205630073 13.80 ENSRNOT00000037064
testis expressed 36
chr3_+_55910177 12.78 ENSRNOT00000009969
kelch-like family member 41
chr20_-_5754773 12.71 ENSRNOT00000035977
inositol hexakisphosphate kinase 3
chr5_-_64946580 12.67 ENSRNOT00000007290
protein phosphatase 3, regulatory subunit B, beta
chr9_+_95285592 10.76 ENSRNOT00000063853
UDP glucuronosyltransferase family 1 member A5
chr3_-_148057523 10.54 ENSRNOT00000055408
defensin beta 24
chr4_-_82194927 10.48 ENSRNOT00000072302
homeobox protein Hox-A9
chr1_-_213534641 10.19 ENSRNOT00000033074
synaptonemal complex central element protein 1
chr5_-_119564846 10.02 ENSRNOT00000012977
cytochrome P450, family 2, subfamily j, polypeptide 4
chr17_-_51912496 9.65 ENSRNOT00000019272
inhibin beta A subunit
chr16_-_75581325 9.63 ENSRNOT00000058031
defensin beta 33
chrX_+_110342718 8.92 ENSRNOT00000043861

chr18_+_70739492 8.88 ENSRNOT00000085601
acetyl-CoA acyltransferase 2
chr6_-_110681408 8.83 ENSRNOT00000078265
angel homolog 1
chr20_+_3677474 8.77 ENSRNOT00000047663
metallothionein 1M
chr7_+_71065197 8.75 ENSRNOT00000051075
retinol dehydrogenase 16 (all-trans)
chr2_-_100372252 8.72 ENSRNOT00000011890
hepatocyte nuclear factor 4, gamma
chr4_+_79868442 8.61 ENSRNOT00000089973
membrane palmitoylated protein 6
chr20_-_29579578 8.45 ENSRNOT00000000700

chrX_-_130794673 8.19 ENSRNOT00000080612
similar to RIKEN cDNA 1700001F22
chr11_+_54137639 8.14 ENSRNOT00000066343
leukocyte surface antigen CD47-like
chr2_-_184993341 7.78 ENSRNOT00000071580
family with sequence similarity 160, member A1
chr1_+_129613497 7.73 ENSRNOT00000074410
tetraspanin-7-like
chr1_-_189181901 7.63 ENSRNOT00000092022
glycoprotein 2
chr12_-_18227991 7.56 ENSRNOT00000072986

chr8_+_72743426 7.34 ENSRNOT00000072573
ribosomal protein S27-like
chr3_+_15788778 7.25 ENSRNOT00000041240
olfactory receptor 397
chr10_+_94192556 7.15 ENSRNOT00000074007
ENSRNOT00000093039
angiotensin I converting enzyme (peptidyl-dipeptidase A) 3
chr2_-_252505971 7.12 ENSRNOT00000021984
dnaj-like protein
chr10_+_65772443 7.07 ENSRNOT00000013296
SEBOX homeobox
chr14_+_2325308 7.07 ENSRNOT00000000072
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E
chr19_+_683484 6.98 ENSRNOT00000090332
telomere repeat binding bouquet formation protein 1
chr15_-_5486590 6.96 ENSRNOT00000040447

chr16_+_71889235 6.83 ENSRNOT00000038266
ADAM metallopeptidase domain 32
chr3_-_146407252 6.82 ENSRNOT00000091310
adipocyte plasma membrane associated protein
chr8_-_43024557 6.53 ENSRNOT00000073494
olfactory receptor 1273
chr10_-_40489808 6.49 ENSRNOT00000037274
solute carrier family 36, member 3
chr20_-_1099336 6.32 ENSRNOT00000071766
olfactory receptor-like protein-like
chr13_-_100189778 6.32 ENSRNOT00000071062
uncharacterized LOC100912759
chr10_-_56530842 6.31 ENSRNOT00000077451

chrX_+_122313470 6.27 ENSRNOT00000018322
similar to hypothetical protein
chr2_+_21931493 6.17 ENSRNOT00000018259
dihydrofolate reductase
chr1_-_154507039 5.99 ENSRNOT00000078883
coiled-coil domain containing 83
chr4_-_22424862 5.87 ENSRNOT00000082359
ATP binding cassette subfamily B member 1A
chr13_-_52834134 5.84 ENSRNOT00000038874
immunoglobulin-like and fibronectin type III domain containing 1
chr6_-_127571016 5.84 ENSRNOT00000057322
serine (or cysteine) peptidase inhibitor, clade A, member 1F
chrX_-_123894411 5.82 ENSRNOT00000034083
reproductive homeobox on X chromosome 2
chr4_-_82280722 5.79 ENSRNOT00000071668
homeobox A9
chr6_-_62798384 5.75 ENSRNOT00000093200
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10-like 1
chr11_+_55474820 5.73 ENSRNOT00000040655
olfactory receptor 1453
chr13_+_49005405 5.50 ENSRNOT00000092560
ENSRNOT00000076457
LEM domain containing 1
chr19_-_43215281 5.42 ENSRNOT00000025052
alanyl-tRNA synthetase
chr5_+_24725821 5.40 ENSRNOT00000061413

chr8_+_117920944 5.38 ENSRNOT00000028125
NME/NM23 nucleoside diphosphate kinase 6
chr10_+_69737328 5.23 ENSRNOT00000055999
ENSRNOT00000076773
transmembrane protein 132E
chr2_+_196334626 5.21 ENSRNOT00000050914
ENSRNOT00000028645
ENSRNOT00000090729
semaphorin 6C
chr10_-_91581232 5.15 ENSRNOT00000066453
ENSRNOT00000068686

chr3_+_138174054 5.07 ENSRNOT00000007946
barrier to autointegration factor 2
chr10_-_12491068 5.01 ENSRNOT00000071158
olfactory receptor 1368
chr4_-_173640684 5.01 ENSRNOT00000010728
RERG like
chr20_+_33527932 4.99 ENSRNOT00000066492
nephrocan
chr2_+_115225356 4.95 ENSRNOT00000073329
olfactory receptor 149-like
chr2_-_222935973 4.91 ENSRNOT00000071934

chr10_-_60006037 4.81 ENSRNOT00000065541
olfactory receptor 1485
chr2_+_115290243 4.76 ENSRNOT00000074802
olfactory receptor 149-like
chr10_-_12236107 4.75 ENSRNOT00000049390
olfactory receptor 1381
chr5_-_134905588 4.74 ENSRNOT00000016013
NOP2/Sun RNA methyltransferase family member 4
chr18_+_40883224 4.71 ENSRNOT00000039733
laeverin
chr1_-_8885967 4.67 ENSRNOT00000016102
gap junction protein, epsilon 1
chr6_-_139973811 4.66 ENSRNOT00000082875
immunoglobulin heavy variable 5-2
chr15_+_35761388 4.54 ENSRNOT00000086118
olfactory receptor 1286
chr8_-_84522588 4.52 ENSRNOT00000076213
muscular LMNA-interacting protein
chr5_+_98998163 4.48 ENSRNOT00000075600
PRAME family member 5
chr10_-_12370656 4.47 ENSRNOT00000060995
olfactory receptor 1362
chr6_+_93385457 4.44 ENSRNOT00000010300
actin-related protein 10 homolog
chr4_-_165787668 4.40 ENSRNOT00000044029
taste receptor, type 2, member 106
chr10_+_12100133 4.31 ENSRNOT00000060987
olfactory receptor 1358
chr2_-_28801223 4.31 ENSRNOT00000020726
transmembrane protein 171
chr9_-_105655471 4.26 ENSRNOT00000014921
similar to 2610034M16Rik protein
chr8_+_42833019 4.25 ENSRNOT00000071050
olfactory receptor 149-like
chr15_-_109316953 4.24 ENSRNOT00000019158
gamma-glutamylamine cyclotransferase
chr15_+_27400717 4.23 ENSRNOT00000047008
olfactory receptor 1620
chr11_+_55497234 4.17 ENSRNOT00000070882
olfactory receptor 2T33-like
chr15_+_5772679 4.07 ENSRNOT00000043553

chr10_+_37582706 4.01 ENSRNOT00000007630
similar to growth and transformation-dependent protein
chr2_-_35192515 4.00 ENSRNOT00000086631
olfactory receptor 149-like
chr8_+_41954140 3.98 ENSRNOT00000049709
olfactory receptor 1223
chr11_-_28940641 3.93 ENSRNOT00000061605
keratin associated protein 22-2
chr3_-_144321602 3.90 ENSRNOT00000049508
similar to Cystatin S precursor (LM protein)
chr16_-_75028977 3.78 ENSRNOT00000058071
defensin beta 13
chr1_+_91005261 3.76 ENSRNOT00000081282
WD repeat domain 62
chr8_+_43408635 3.75 ENSRNOT00000043988
olfactory receptor 1313
chr4_+_72272809 3.73 ENSRNOT00000048987
olfactory receptor 808
chr8_-_43304560 3.70 ENSRNOT00000060092
olfactory receptor 1307
chr11_+_28724341 3.62 ENSRNOT00000049858
RIKEN cDNA 2310034C09-like
chr1_-_238381871 3.60 ENSRNOT00000077601
transmembrane channel-like 1
chr1_+_74770009 3.55 ENSRNOT00000012225

chr10_-_12644292 3.55 ENSRNOT00000041612
olfactory receptor 1375
chr20_+_11612383 3.51 ENSRNOT00000045125

chr3_-_20518105 3.46 ENSRNOT00000050435

chr11_-_30300139 3.43 ENSRNOT00000079267

chr7_+_142756312 3.40 ENSRNOT00000071298
ankyrin repeat domain 33
chr10_+_12332142 3.40 ENSRNOT00000071686
olfactory receptor 1361
chr5_+_141530211 3.38 ENSRNOT00000056546
Riken cDNA 4933427I04 gene
chr3_+_73335149 3.35 ENSRNOT00000042537
olfactory receptor 470
chr17_-_10208360 3.34 ENSRNOT00000087397
unc-5 netrin receptor A
chr14_+_7026769 3.33 ENSRNOT00000071955
secretory calcium-binding phosphoprotein proline-glutamine rich 1-like
chr4_-_121969446 3.33 ENSRNOT00000085001
vomeronasal 1 receptor 99
chr7_+_13378338 3.30 ENSRNOT00000042747
olfactory receptor 1073
chr20_+_649582 3.27 ENSRNOT00000074145
olfactory receptor 1687
chr4_+_7257752 3.27 ENSRNOT00000088357
transmembrane and ubiquitin-like domain containing 1
chr15_-_12889102 3.27 ENSRNOT00000061214
ENSRNOT00000084687
similar to HT021
chr10_-_12731897 3.27 ENSRNOT00000042582
olfactory receptor 1378
chr1_+_230056710 3.27 ENSRNOT00000073539
olfactory receptor 357
chr10_-_12522230 3.25 ENSRNOT00000073401
olfactory receptor 1370
chr3_+_102471249 3.25 ENSRNOT00000051083
olfactory receptor 749
chr15_+_27438853 3.25 ENSRNOT00000011636
olfactory receptor 1622
chr2_+_25007218 3.23 ENSRNOT00000078413
uncharacterized LOC100912266
chr11_-_28736000 3.21 ENSRNOT00000064058
keratin associated protein 14 like
chr10_-_60126696 3.17 ENSRNOT00000026857
olfactory receptor 1485
chr11_+_28739219 3.13 ENSRNOT00000061620
keratin associated protein 13-2
chr18_-_27206777 3.12 ENSRNOT00000090569

chr8_-_43443531 3.11 ENSRNOT00000007901
olfactory receptor 148-like
chrX_-_138435391 3.09 ENSRNOT00000043258
muscleblind-like splicing regulator 3
chr15_-_46223385 3.07 ENSRNOT00000059211
defensin beta 30
chr5_-_134382794 3.06 ENSRNOT00000016714
5-methylcytosine rRNA methyltransferase NSUN4
chr2_-_153140894 3.04 ENSRNOT00000075166

chr8_-_17833773 3.04 ENSRNOT00000049758
olfactory receptor 1117
chr8_-_37349694 3.02 ENSRNOT00000030776
rCG64165-like
chr2_+_234298839 3.01 ENSRNOT00000072216
Dcm5 protein
chr1_+_168830222 2.99 ENSRNOT00000050333
olfactory receptor 122
chr2_-_199529864 2.99 ENSRNOT00000023742
olfactory receptor 390
chr13_+_71656651 2.97 ENSRNOT00000050365
zinc finger protein 648
chr11_-_60819249 2.96 ENSRNOT00000043917
ENSRNOT00000042447
CD200 receptor 1-like
chr2_+_233909142 2.90 ENSRNOT00000073197
Dcm5 protein
chr17_+_87274944 2.89 ENSRNOT00000073718
enhancer trap locus 4
chr4_-_130659697 2.89 ENSRNOT00000072374
rCG56280-like
chr2_+_46223006 2.86 ENSRNOT00000073159
olfactory receptor 1265
chr1_+_167719947 2.81 ENSRNOT00000024971
olfactory receptor 43
chr8_-_42793484 2.78 ENSRNOT00000072871

chr16_-_75208230 2.78 ENSRNOT00000058059
defensin beta 10
chr3_-_103447716 2.70 ENSRNOT00000074196
olfactory receptor 791
chr11_+_43194348 2.69 ENSRNOT00000075303
olfactory receptor 1532
chr8_+_43355060 2.68 ENSRNOT00000043206
olfactory receptor 1309
chr18_+_16590408 2.67 ENSRNOT00000093715
molybdenum cofactor sulfurase
chr5_-_173312023 2.67 ENSRNOT00000026671
taste 1 receptor member 3
chr8_+_18845579 2.63 ENSRNOT00000039181
olfactory receptor 1125
chr1_-_99955717 2.63 ENSRNOT00000079624
kallikrein 1-related peptidase C6
chr1_+_169208988 2.62 ENSRNOT00000050606
olfactory receptor 140
chr1_+_213258684 2.60 ENSRNOT00000091678
olfactory receptor 13A1-like
chr5_+_173248245 2.57 ENSRNOT00000025213
mitochondrial ribosomal protein L20
chr1_+_229461127 2.46 ENSRNOT00000035813
olfactory receptor 332
chr15_-_27032498 2.45 ENSRNOT00000016702
olfactory receptor 1609
chr3_+_76035198 2.43 ENSRNOT00000080503
olfactory receptor 596
chr12_+_19561347 2.41 ENSRNOT00000060025
similar to family with sequence similarity 55, member C
chr12_-_35318685 2.41 ENSRNOT00000074199

chr12_-_21450204 2.39 ENSRNOT00000065866
zinc finger CW-type PWWP domain protein 1-like
chr8_-_43082948 2.37 ENSRNOT00000072050
olfactory receptor 8G5-like
chr10_-_110308514 2.36 ENSRNOT00000054927
testis expressed gene 19.2
chr11_+_43476319 2.35 ENSRNOT00000044928
olfactory receptor 1548
chr7_-_13531526 2.35 ENSRNOT00000048054
olfactory receptor 1081
chr17_-_15519282 2.33 ENSRNOT00000093577
asporin-like 1
chr7_-_13553963 2.30 ENSRNOT00000079450
olfactory receptor 1082
chr10_-_16046033 2.29 ENSRNOT00000089460
cytoplasmic polyadenylation element binding protein 4
chr7_+_13673934 2.25 ENSRNOT00000048564
olfactory receptor 1085
chr3_+_72974274 2.25 ENSRNOT00000072310
olfactory receptor 443
chr3_-_158985814 2.19 ENSRNOT00000071070
olfactory receptor 150-like
chr10_-_12674077 2.18 ENSRNOT00000041353
olfactory receptor 1376
chr1_-_86749728 2.15 ENSRNOT00000047766
similar to putative pheromone receptor (Go-VN5)
chr7_-_145575981 2.06 ENSRNOT00000074622
16.5 kDa submandibular gland glycoprotein-like
chr7_+_13631975 2.06 ENSRNOT00000083548
olfactory receptor 1084
chr10_-_88000423 2.06 ENSRNOT00000076787
ENSRNOT00000046751
ENSRNOT00000091394
keratin 32
chr16_-_14300951 2.04 ENSRNOT00000017038
retinal G protein coupled receptor
chr8_+_42650438 2.03 ENSRNOT00000047107
olfactory receptor 147-like
chr1_+_230553486 2.02 ENSRNOT00000017572
olfactory receptor 373
chr3_-_45169118 1.95 ENSRNOT00000086371
coiled-coil domain containing 148
chr1_+_64241865 1.92 ENSRNOT00000082095
T cell-interacting, activating receptor on myeloid cells 1
chr1_+_247871807 1.90 ENSRNOT00000089563
melan-A
chr7_-_12429897 1.87 ENSRNOT00000020670
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr1_-_167770210 1.85 ENSRNOT00000024948
olfactory receptor 47
chr18_+_16590197 1.83 ENSRNOT00000066583
molybdenum cofactor sulfurase
chr1_+_205911552 1.78 ENSRNOT00000024751
fibronectin type 3 and ankyrin repeat domains 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Neurog2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
8.3 25.0 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
6.0 23.8 GO:0043490 malate-aspartate shuttle(GO:0043490)
5.3 21.0 GO:0001834 trophectodermal cell proliferation(GO:0001834)
3.9 23.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
3.2 16.2 GO:0034334 desmosome assembly(GO:0002159) adherens junction maintenance(GO:0034334)
3.1 18.4 GO:0042851 L-alanine metabolic process(GO:0042851)
2.5 24.8 GO:0018298 protein-chromophore linkage(GO:0018298)
2.4 9.6 GO:0060279 positive regulation of ovulation(GO:0060279)
1.9 7.6 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
1.8 8.9 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
1.5 5.9 GO:0033231 carbohydrate export(GO:0033231) daunorubicin transport(GO:0043215) response to borneol(GO:1905230) cellular response to borneol(GO:1905231) response to codeine(GO:1905233) response to quercetin(GO:1905235) drug transport across blood-brain barrier(GO:1990962) establishment of blood-retinal barrier(GO:1990963)
1.4 37.8 GO:0019373 epoxygenase P450 pathway(GO:0019373)
1.4 5.4 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
1.2 6.2 GO:0006545 glycine biosynthetic process(GO:0006545)
1.2 10.8 GO:0052697 xenobiotic glucuronidation(GO:0052697)
1.1 8.8 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
1.1 1.1 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795)
1.0 12.8 GO:2000291 regulation of myoblast proliferation(GO:2000291)
1.0 45.4 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.8 6.5 GO:0015808 L-alanine transport(GO:0015808)
0.7 3.6 GO:0060005 vestibular reflex(GO:0060005)
0.7 4.7 GO:0042256 mature ribosome assembly(GO:0042256)
0.6 7.0 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.6 15.7 GO:2000757 negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.6 1.7 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.6 3.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.5 2.7 GO:0001582 detection of chemical stimulus involved in sensory perception of sweet taste(GO:0001582)
0.5 19.9 GO:0008209 androgen metabolic process(GO:0008209)
0.5 5.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.5 12.7 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.4 5.8 GO:0042118 endothelial cell activation(GO:0042118)
0.4 4.5 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.4 1.5 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.4 3.8 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.4 10.2 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.4 1.4 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.3 8.9 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.3 1.7 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.3 0.8 GO:0014016 neuroblast differentiation(GO:0014016)
0.2 7.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 16.0 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.2 3.1 GO:0031167 rRNA methylation(GO:0031167)
0.2 1.4 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.2 1.2 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.2 1.0 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.2 10.5 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.2 4.7 GO:0043171 peptide catabolic process(GO:0043171)
0.2 4.5 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.2 4.2 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.2 0.5 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.2 0.9 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.1 188.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 3.4 GO:2000678 negative regulation of transcription regulatory region DNA binding(GO:2000678)
0.1 16.0 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 3.8 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.1 3.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 1.3 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 2.0 GO:0007602 phototransduction(GO:0007602)
0.1 0.7 GO:0016584 nucleosome positioning(GO:0016584)
0.1 5.0 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.1 0.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 4.7 GO:0002088 lens development in camera-type eye(GO:0002088)
0.1 0.6 GO:0051095 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.1 4.4 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.7 GO:0051198 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.0 1.6 GO:0060043 regulation of cardiac muscle cell proliferation(GO:0060043)
0.0 3.3 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 2.7 GO:0048477 oogenesis(GO:0048477)
0.0 0.7 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.8 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 6.7 GO:0030522 intracellular receptor signaling pathway(GO:0030522)
0.0 0.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 2.6 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.4 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.8 GO:0018149 peptide cross-linking(GO:0018149)
0.0 2.7 GO:0007411 axon guidance(GO:0007411)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.3 25.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
4.2 21.0 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
3.2 9.6 GO:0043511 inhibin complex(GO:0043511)
1.2 5.8 GO:0070469 respiratory chain(GO:0070469)
1.0 12.8 GO:0031143 pseudopodium(GO:0031143)
0.8 15.9 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.8 10.2 GO:0000801 central element(GO:0000801)
0.8 16.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.7 7.0 GO:0070187 telosome(GO:0070187)
0.5 7.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.5 2.7 GO:1903767 sweet taste receptor complex(GO:1903767) taste receptor complex(GO:1903768)
0.5 5.9 GO:0046581 intercellular canaliculus(GO:0046581)
0.3 5.0 GO:0005614 interstitial matrix(GO:0005614)
0.3 1.3 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.3 3.6 GO:0032426 stereocilium tip(GO:0032426)
0.2 1.9 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.2 4.7 GO:0005922 connexon complex(GO:0005922)
0.2 3.8 GO:0005682 U5 snRNP(GO:0005682)
0.2 10.4 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 21.5 GO:0072562 blood microparticle(GO:0072562)
0.2 1.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.2 8.8 GO:0005801 cis-Golgi network(GO:0005801)
0.2 1.5 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 0.9 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 8.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 7.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.7 GO:0016589 NURF complex(GO:0016589)
0.1 3.3 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 1.4 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 7.6 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.6 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 26.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 7.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 67.9 GO:0005615 extracellular space(GO:0005615)
0.1 4.8 GO:0005902 microvillus(GO:0005902)
0.0 1.4 GO:0044439 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 0.8 GO:0001533 cornified envelope(GO:0001533)
0.0 51.7 GO:0005739 mitochondrion(GO:0005739)
0.0 1.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 2.2 GO:0030018 Z disc(GO:0030018)
0.0 2.1 GO:0005882 intermediate filament(GO:0005882)
0.0 85.0 GO:0016021 integral component of membrane(GO:0016021)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 18.4 GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
5.0 24.8 GO:0019862 IgA binding(GO:0019862)
4.8 23.8 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
4.0 15.9 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
3.6 25.0 GO:0030492 hemoglobin binding(GO:0030492)
3.3 10.0 GO:0008405 arachidonic acid 11,12-epoxygenase activity(GO:0008405)
2.8 19.9 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
2.4 9.6 GO:0070699 type II activin receptor binding(GO:0070699)
1.8 7.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
1.8 16.0 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
1.6 4.7 GO:0008169 C-methyltransferase activity(GO:0008169)
1.5 6.2 GO:0051870 methotrexate binding(GO:0051870)
1.4 12.7 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
1.4 5.4 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
1.3 6.5 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
1.3 8.9 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
1.2 16.2 GO:0045294 alpha-catenin binding(GO:0045294)
1.2 5.9 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
1.1 4.5 GO:0008265 Mo-molybdopterin cofactor sulfurase activity(GO:0008265)
1.1 4.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
1.0 27.8 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
1.0 6.8 GO:0004064 arylesterase activity(GO:0004064)
1.0 21.0 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.8 8.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.8 6.8 GO:0008494 translation activator activity(GO:0008494)
0.7 3.3 GO:0005042 netrin receptor activity(GO:0005042)
0.5 2.7 GO:0033041 sweet taste receptor activity(GO:0033041)
0.5 9.6 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.4 51.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.4 21.3 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.4 5.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.4 3.6 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.3 10.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.3 5.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.3 3.8 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.3 0.8 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.2 4.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 1.1 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 1.4 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.2 1.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 0.5 GO:0015154 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2 1.4 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 188.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 3.3 GO:0015288 porin activity(GO:0015288)
0.1 8.7 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 1.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.5 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.1 24.9 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.1 8.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 7.1 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.1 1.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 1.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 0.7 GO:0035325 Toll-like receptor binding(GO:0035325)
0.0 2.6 GO:0019843 rRNA binding(GO:0019843)
0.0 0.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 3.3 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.7 GO:0031491 nucleosome binding(GO:0031491)
0.0 2.3 GO:0008168 methyltransferase activity(GO:0008168)
0.0 5.6 GO:0004930 G-protein coupled receptor activity(GO:0004930)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 21.0 PID IGF1 PATHWAY IGF1 pathway
0.1 4.4 PID ALK1 PATHWAY ALK1 signaling events
0.1 31.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 3.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 6.2 PID E2F PATHWAY E2F transcription factor network
0.1 7.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.4 PID ATR PATHWAY ATR signaling pathway
0.0 1.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 18.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
1.0 9.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.6 23.8 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.6 10.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.6 8.9 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.5 6.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.3 2.0 REACTOME OPSINS Genes involved in Opsins
0.2 3.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 5.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.2 4.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 23.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 2.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.6 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 4.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 0.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 0.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.4 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 1.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.4 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells