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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Neurod2_Bhlha15_Bhlhe22_Olig1

Z-value: 0.46

Motif logo

Transcription factors associated with Neurod2_Bhlha15_Bhlhe22_Olig1

Gene Symbol Gene ID Gene Info
ENSRNOG00000028417 Neurod2
ENSRNOG00000025164 basic helix-loop-helix family, member a15
ENSRNOG00000021745 basic helix-loop-helix family, member e22
ENSRNOG00000028648 oligodendrocyte transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Bhlha15rn6_v1_chr12_-_12407561_124075610.091.1e-01Click!
Bhlhe22rn6_v1_chr2_+_102685513_1026855130.081.8e-01Click!
Olig1rn6_v1_chr11_+_31428358_31428358-0.018.6e-01Click!

Activity profile of Neurod2_Bhlha15_Bhlhe22_Olig1 motif

Sorted Z-values of Neurod2_Bhlha15_Bhlhe22_Olig1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_128003418 34.41 ENSRNOT00000013896
serine (or cysteine) proteinase inhibitor, clade A, member 3C
chr6_+_128048099 28.02 ENSRNOT00000084685
ENSRNOT00000087017
Ab1-233
chr13_+_89597138 22.50 ENSRNOT00000004662
apolipoprotein A2
chr1_+_148240504 21.82 ENSRNOT00000085373
Cytochrome P450, family 2, subfamily c, polypeptide 7-like
chr4_-_31730386 18.08 ENSRNOT00000013817
solute carrier family 25 member 13
chr7_+_28414350 17.11 ENSRNOT00000085680
insulin-like growth factor 1
chr19_-_22632071 16.48 ENSRNOT00000077275
glutamic--pyruvic transaminase 2
chr2_-_100372252 13.87 ENSRNOT00000011890
hepatocyte nuclear factor 4, gamma
chr4_-_82194927 12.77 ENSRNOT00000072302
homeobox protein Hox-A9
chr15_+_28028521 11.87 ENSRNOT00000089631

chr1_-_189181901 9.50 ENSRNOT00000092022
glycoprotein 2
chr17_+_69468427 8.11 ENSRNOT00000058413
similar to 20-alpha-hydroxysteroid dehydrogenase
chr3_-_123179644 7.47 ENSRNOT00000028835
leucine zipper tumor suppressor family member 3
chr1_+_189364288 7.22 ENSRNOT00000080338
acyl-CoA synthetase medium-chain family member 1
chr10_+_99388130 6.86 ENSRNOT00000006238
potassium voltage-gated channel subfamily J member 16
chrX_-_138435391 5.66 ENSRNOT00000043258
muscleblind-like splicing regulator 3
chr4_+_122365093 5.47 ENSRNOT00000024011
Kruppel-like factor 15
chr17_+_30556884 5.41 ENSRNOT00000080929
ENSRNOT00000022022
enoyl-CoA delta isomerase 2
chr8_-_130550388 5.31 ENSRNOT00000026355
cytochrome P450, family 8, subfamily b, polypeptide 1
chr1_-_205630073 5.23 ENSRNOT00000037064
testis expressed 36
chr8_-_111777602 5.14 ENSRNOT00000052317
ENSRNOT00000083855
similar to RIKEN cDNA 1300017J02
chr3_+_128155069 5.12 ENSRNOT00000051184
ENSRNOT00000006389
phospholipase C beta 1
chr6_-_110681408 4.77 ENSRNOT00000078265
angel homolog 1
chr15_-_109316953 4.39 ENSRNOT00000019158
gamma-glutamylamine cyclotransferase
chr3_+_40038336 4.32 ENSRNOT00000048804
polypeptide N-acetylgalactosaminyltransferase 13
chr10_-_16046033 4.30 ENSRNOT00000089460
cytoplasmic polyadenylation element binding protein 4
chr10_-_16045835 4.29 ENSRNOT00000064832
cytoplasmic polyadenylation element binding protein 4
chr5_-_64946580 4.17 ENSRNOT00000007290
protein phosphatase 3, regulatory subunit B, beta
chr11_+_54137639 4.12 ENSRNOT00000066343
leukocyte surface antigen CD47-like
chrX_+_6273733 3.89 ENSRNOT00000074275
NDP, norrin cystine knot growth factor
chr6_+_36089433 3.86 ENSRNOT00000090438
ENSRNOT00000005731
5'-nucleotidase, cytosolic IB
chr1_-_201894775 3.78 ENSRNOT00000050519
CUB and zona pellucida-like domains 1
chr13_+_56096834 3.74 ENSRNOT00000035129
DENN domain containing 1B
chr13_-_56958549 3.70 ENSRNOT00000017293
ENSRNOT00000083912
similar to complement factor H-related protein
chr2_+_196334626 3.61 ENSRNOT00000050914
ENSRNOT00000028645
ENSRNOT00000090729
semaphorin 6C
chr3_-_66417741 3.45 ENSRNOT00000007662
neuronal differentiation 1
chr19_+_683484 3.43 ENSRNOT00000090332
telomere repeat binding bouquet formation protein 1
chr4_-_22424862 3.29 ENSRNOT00000082359
ATP binding cassette subfamily B member 1A
chr17_-_10208360 3.24 ENSRNOT00000087397
unc-5 netrin receptor A
chr8_+_69971778 3.24 ENSRNOT00000058007
ENSRNOT00000037941
ENSRNOT00000050649
multiple EGF-like-domains 11
chr3_-_39596718 3.12 ENSRNOT00000006784
reprimo, TP53 dependent G2 arrest mediator candidate
chrX_-_130794673 2.96 ENSRNOT00000080612
similar to RIKEN cDNA 1700001F22
chr3_-_146407252 2.85 ENSRNOT00000091310
adipocyte plasma membrane associated protein
chr7_-_52404774 2.79 ENSRNOT00000082100
neuron navigator 3
chr3_-_145810834 2.75 ENSRNOT00000075429
zinc finger protein 120-like
chr7_-_132343169 2.54 ENSRNOT00000021064
ATP binding cassette subfamily D member 2
chr1_-_266428239 2.53 ENSRNOT00000027160
cytochrome P450, family 17, subfamily a, polypeptide 1
chr17_-_51912496 2.51 ENSRNOT00000019272
inhibin beta A subunit
chr4_-_82280722 2.45 ENSRNOT00000071668
homeobox A9
chr9_-_82477136 2.37 ENSRNOT00000026753
ENSRNOT00000089555
regulated endocrine-specific protein 18
chr1_+_129613497 2.37 ENSRNOT00000074410
tetraspanin-7-like
chr4_+_79868442 2.35 ENSRNOT00000089973
membrane palmitoylated protein 6
chr1_-_189238776 2.32 ENSRNOT00000020817
protein disulfide isomerase-like, testis expressed
chr3_-_78235760 2.26 ENSRNOT00000008435
olfactory receptor 698
chr3_+_145764932 2.23 ENSRNOT00000075257

chr1_+_72810545 2.23 ENSRNOT00000092117
protein tyrosine phosphatase, receptor type, H
chr5_+_98469047 2.12 ENSRNOT00000041374
leucine rich adaptor protein 1-like
chr7_-_70328148 2.08 ENSRNOT00000074645
methyltransferase like 21B
chr10_-_110308514 1.95 ENSRNOT00000054927
testis expressed gene 19.2
chr10_+_69737328 1.84 ENSRNOT00000055999
ENSRNOT00000076773
transmembrane protein 132E
chr1_+_167719947 1.80 ENSRNOT00000024971
olfactory receptor 43
chr20_-_1099336 1.76 ENSRNOT00000071766
olfactory receptor-like protein-like
chr14_+_22107416 1.71 ENSRNOT00000060179
ENSRNOT00000080114
sulfotransferase family 1D, member 1
chr2_+_148722231 1.71 ENSRNOT00000018022
eukaryotic translation initiation factor 2A
chr10_+_74959285 1.67 ENSRNOT00000010296
ring finger protein 43
chr2_+_198721724 1.65 ENSRNOT00000043535
ankyrin repeat domain 34A
chr19_-_42180981 1.55 ENSRNOT00000019577
polyamine modulated factor 1 binding protein 1
chr3_-_38090526 1.54 ENSRNOT00000059430
calcium voltage-gated channel auxiliary subunit beta 4
chr13_-_104080631 1.50 ENSRNOT00000032865
lysophospholipase-like 1
chr15_-_49505553 1.49 ENSRNOT00000028974
ADAM-like, decysin 1
chr5_-_2982603 1.48 ENSRNOT00000045460
potassium voltage-gated channel subfamily B member 2
chr1_+_205911552 1.46 ENSRNOT00000024751
fibronectin type 3 and ankyrin repeat domains 1
chrY_-_1398030 1.43 ENSRNOT00000088719
ubiquitin specific peptidase 9, Y-linked
chr4_-_84740909 1.38 ENSRNOT00000013088
secernin 1
chr12_-_38504774 1.37 ENSRNOT00000011286
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr20_+_5535432 1.36 ENSRNOT00000040859
synaptic Ras GTPase activating protein 1
chr18_-_19275273 1.36 ENSRNOT00000041707
lateral signaling target protein 2 homolog
chr14_+_77922045 1.33 ENSRNOT00000081198
serine/threonine kinase 32B
chr2_-_259382765 1.27 ENSRNOT00000091407
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr18_+_80939875 1.26 ENSRNOT00000021729
zinc binding alcohol dehydrogenase, domain containing 2
chr2_+_208738132 1.23 ENSRNOT00000023972

chr10_+_36517169 1.23 ENSRNOT00000040534
olfactory receptor 1408
chr15_+_27400717 1.21 ENSRNOT00000047008
olfactory receptor 1620
chr10_-_12491068 1.19 ENSRNOT00000071158
olfactory receptor 1368
chrX_-_111365849 1.17 ENSRNOT00000088979
nucleoporin 62 C-terminal like
chr15_-_57651041 1.16 ENSRNOT00000072138
spermatid associated
chr10_+_38788992 1.16 ENSRNOT00000009727
growth differentiation factor 9
chr13_+_49003803 1.15 ENSRNOT00000080556
LEM domain containing 1
chr8_-_43443531 1.15 ENSRNOT00000007901
olfactory receptor 148-like
chr3_+_152630415 1.15 ENSRNOT00000027369
AAR2 splicing factor homolog
chr10_-_12731897 1.14 ENSRNOT00000042582
olfactory receptor 1378
chr2_+_179952227 1.13 ENSRNOT00000015081
platelet derived growth factor C
chr5_+_104362971 1.12 ENSRNOT00000058520
ADAMTS-like 1
chr10_-_12644292 1.11 ENSRNOT00000041612
olfactory receptor 1375
chr4_-_173640684 1.10 ENSRNOT00000010728
RERG like
chr11_+_9642365 1.09 ENSRNOT00000087080
ENSRNOT00000042384
roundabout guidance receptor 1
chr8_+_19548488 1.08 ENSRNOT00000008605
olfactory receptor 1148
chr7_-_145338152 1.06 ENSRNOT00000055268
salivary protein 1
chr6_+_52663112 1.04 ENSRNOT00000013842
ataxin 7-like 1
chrX_+_110342718 1.02 ENSRNOT00000043861

chr6_+_18880737 1.00 ENSRNOT00000003432
alkB homolog 8, tRNA methyltransferase
chr7_-_145575981 0.99 ENSRNOT00000074622
16.5 kDa submandibular gland glycoprotein-like
chr10_-_12370656 0.98 ENSRNOT00000060995
olfactory receptor 1362
chrX_-_18341467 0.97 ENSRNOT00000045802
spindlin family, member 2A
chrX_-_143274180 0.97 ENSRNOT00000051550
MCF.2 cell line derived transforming sequence
chr20_-_5485837 0.95 ENSRNOT00000092272
ENSRNOT00000000559
ENSRNOT00000092597
death-domain associated protein
chr2_+_54660722 0.95 ENSRNOT00000060376
maestro heat-like repeat family member 2B
chr5_-_66322567 0.95 ENSRNOT00000032726
cylicin 2
chr3_-_103460529 0.90 ENSRNOT00000047274
olfactory receptor 4F6-like
chr11_+_43194348 0.90 ENSRNOT00000075303
olfactory receptor 1532
chr7_-_118518193 0.88 ENSRNOT00000075636
zinc finger protein 250-like
chr19_-_39267928 0.87 ENSRNOT00000027686
transmembrane p24 trafficking protein 6
chrX_+_122313470 0.87 ENSRNOT00000018322
similar to hypothetical protein
chr11_+_55497234 0.86 ENSRNOT00000070882
olfactory receptor 2T33-like
chr10_-_91581232 0.86 ENSRNOT00000066453
ENSRNOT00000068686

chr3_+_5167685 0.85 ENSRNOT00000046109
lipocalin 4
chr10_-_12674077 0.85 ENSRNOT00000041353
olfactory receptor 1376
chr5_-_128446725 0.84 ENSRNOT00000011272
basic transcription factor 3-like 4
chr16_+_2706428 0.83 ENSRNOT00000077117
interleukin 17 receptor D
chr4_-_39102807 0.83 ENSRNOT00000052063
thrombospondin type 1 domain containing 7A
chr7_-_120518653 0.82 ENSRNOT00000016362
BAI1-associated protein 2-like 2
chr2_-_154763094 0.79 ENSRNOT00000031015
vomeronasal 2 receptor, 46
chr4_-_165787668 0.79 ENSRNOT00000044029
taste receptor, type 2, member 106
chr1_+_228690119 0.79 ENSRNOT00000087169
pore forming protein-like
chr16_+_35573058 0.79 ENSRNOT00000059580
polypeptide N-acetylgalactosaminyltransferase-like 6
chr1_-_8885967 0.78 ENSRNOT00000016102
gap junction protein, epsilon 1
chr2_+_210381829 0.76 ENSRNOT00000024611
ALX homeobox 3
chr2_-_2779109 0.76 ENSRNOT00000017098
Rieske (Fe-S) domain containing
chr9_-_105655471 0.76 ENSRNOT00000014921
similar to 2610034M16Rik protein
chr15_+_46179787 0.75 ENSRNOT00000059213
defensin beta 41
chr16_-_75241303 0.75 ENSRNOT00000058056
defensin beta 2
chr12_-_18526250 0.74 ENSRNOT00000001791
acetylserotonin O-methyltransferase
chr9_+_112360419 0.73 ENSRNOT00000086682
mannosidase, alpha, class 2A, member 1
chr6_-_86223052 0.72 ENSRNOT00000046828
fibrous sheath CABYR binding protein
chr1_+_89149998 0.70 ENSRNOT00000056742
hypothetical protein LOC688924
chr3_+_103637469 0.70 ENSRNOT00000088881
olfactory receptor 795
chr20_+_649582 0.69 ENSRNOT00000074145
olfactory receptor 1687
chr10_-_60006037 0.69 ENSRNOT00000065541
olfactory receptor 1485
chr1_+_212651917 0.68 ENSRNOT00000025635
olfactory receptor 287
chr5_-_12563429 0.68 ENSRNOT00000059625
suppression of tumorigenicity 18
chr3_+_147511563 0.68 ENSRNOT00000006828
solute carrier family 52 member 3
chr8_-_28044876 0.67 ENSRNOT00000072152
acyl-CoA dehydrogenase family, member 8
chr12_+_41600005 0.67 ENSRNOT00000001872
phospholipase B domain containing 2
chr12_-_18227991 0.67 ENSRNOT00000072986

chr20_-_11626876 0.67 ENSRNOT00000001635
keratin associated protein 12-1-like
chrX_-_154918095 0.66 ENSRNOT00000085224
elongation factor 1-alpha 1-like
chr4_-_121969446 0.66 ENSRNOT00000085001
vomeronasal 1 receptor 99
chrX_+_156319687 0.66 ENSRNOT00000091147
ENSRNOT00000079378
family with sequence similarity 3, member A
chr7_+_13378338 0.65 ENSRNOT00000042747
olfactory receptor 1073
chr9_+_60900213 0.65 ENSRNOT00000017859
coiled-coil domain containing 150
chr15_+_27438853 0.64 ENSRNOT00000011636
olfactory receptor 1622
chr10_-_16910641 0.64 ENSRNOT00000005273
endoplasmic reticulum-golgi intermediate compartment 1
chr1_+_188278469 0.62 ENSRNOT00000065601
transmembrane channel-like 5
chr1_+_164425475 0.61 ENSRNOT00000023386
kelch-like family member 35
chr11_+_68633160 0.61 ENSRNOT00000063795
SEC22 homolog A, vesicle trafficking protein
chr1_-_238381871 0.60 ENSRNOT00000077601
transmembrane channel-like 1
chr19_+_24329544 0.59 ENSRNOT00000080934
TBC1 domain family member 9
chr6_-_127571016 0.59 ENSRNOT00000057322
serine (or cysteine) peptidase inhibitor, clade A, member 1F
chr1_+_168655404 0.58 ENSRNOT00000021307
olfactory receptor 110
chr20_+_29445510 0.58 ENSRNOT00000044805
DnaJ heat shock protein family (Hsp40) member B12
chr1_-_198706852 0.57 ENSRNOT00000024074
dCTP pyrophosphatase 1
chr4_-_67610710 0.57 ENSRNOT00000039067
mitochondrial ribosomal protein S33
chr2_-_199529864 0.57 ENSRNOT00000023742
olfactory receptor 390
chr3_+_138174054 0.56 ENSRNOT00000007946
barrier to autointegration factor 2
chr6_+_136245027 0.56 ENSRNOT00000086997
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A
chr10_-_60772313 0.54 ENSRNOT00000050847
olfactory receptor 1504
chr3_+_147511406 0.54 ENSRNOT00000082438
solute carrier family 52 member 3
chrX_-_153491837 0.53 ENSRNOT00000089027
eukaryotic translation elongation factor 1 alpha 1-like
chr20_+_29558689 0.52 ENSRNOT00000085229
activating signal cointegrator 1 complex subunit 1
chr5_+_79367663 0.52 ENSRNOT00000011508
ATPase H+ transporting V1 subunit G1
chr1_+_215135482 0.51 ENSRNOT00000079062
ENSRNOT00000064138
ENSRNOT00000054866

chr4_-_130659697 0.51 ENSRNOT00000072374
rCG56280-like
chr19_+_60104804 0.50 ENSRNOT00000078559
par-3 family cell polarity regulator
chr8_-_55171718 0.50 ENSRNOT00000080736
hypothetical protein LOC689959
chr1_-_217620420 0.49 ENSRNOT00000092783
cortactin
chr7_-_117978787 0.48 ENSRNOT00000074262
zinc finger protein 647
chr20_-_11644166 0.47 ENSRNOT00000073009
keratin associated protein 12-1-like
chr3_+_78876609 0.47 ENSRNOT00000049936
olfactory receptor 726
chr5_+_141530211 0.47 ENSRNOT00000056546
Riken cDNA 4933427I04 gene
chr3_+_15788778 0.46 ENSRNOT00000041240
olfactory receptor 397
chr17_+_87274944 0.45 ENSRNOT00000073718
enhancer trap locus 4
chr3_+_102471249 0.45 ENSRNOT00000051083
olfactory receptor 749
chrX_+_70354360 0.43 ENSRNOT00000076852
ENSRNOT00000029046
diacylglycerol O-acyltransferase 2-like 6
chr3_-_173839433 0.43 ENSRNOT00000075547

chr6_-_44363915 0.42 ENSRNOT00000085925
inhibitor of DNA binding 2, HLH protein
chr16_-_75028977 0.42 ENSRNOT00000058071
defensin beta 13
chr1_+_169074475 0.42 ENSRNOT00000050248
olfactory receptor 132
chr8_-_43470377 0.42 ENSRNOT00000050312
olfactory receptor 149
chr7_-_120839577 0.42 ENSRNOT00000018526
DNA meiotic recombinase 1
chr3_+_37545238 0.41 ENSRNOT00000070792
TNF alpha induced protein 6
chr10_-_12236107 0.41 ENSRNOT00000049390
olfactory receptor 1381
chr2_+_234298839 0.41 ENSRNOT00000072216
Dcm5 protein
chr3_-_103447716 0.39 ENSRNOT00000074196
olfactory receptor 791
chr10_-_4910305 0.39 ENSRNOT00000033122
RecQ mediated genome instability 2
chr8_-_43304560 0.39 ENSRNOT00000060092
olfactory receptor 1307
chr15_-_28786094 0.37 ENSRNOT00000044250
olfactory receptor 1639
chr10_+_34631398 0.37 ENSRNOT00000046027
olfactory receptor 1391
chr1_+_168830222 0.36 ENSRNOT00000050333
olfactory receptor 122
chr1_-_149859479 0.36 ENSRNOT00000052199
olfactory receptor 14A2-like
chr5_+_98998163 0.35 ENSRNOT00000075600
PRAME family member 5

Network of associatons between targets according to the STRING database.

First level regulatory network of Neurod2_Bhlha15_Bhlhe22_Olig1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.5 22.5 GO:0046340 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) diacylglycerol catabolic process(GO:0046340)
4.5 18.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
4.3 17.1 GO:0001834 trophectodermal cell proliferation(GO:0001834)
2.7 16.5 GO:0042851 L-alanine metabolic process(GO:0042851)
2.4 9.5 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
1.7 5.1 GO:0035723 interleukin-12-mediated signaling pathway(GO:0035722) interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-12(GO:0071349) cellular response to interleukin-15(GO:0071350) regulation of monocyte extravasation(GO:2000437)
0.9 8.6 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.8 2.5 GO:0010034 response to acetate(GO:0010034)
0.8 3.3 GO:0043215 carbohydrate export(GO:0033231) daunorubicin transport(GO:0043215) response to borneol(GO:1905230) cellular response to borneol(GO:1905231) response to codeine(GO:1905233) response to quercetin(GO:1905235) drug transport across blood-brain barrier(GO:1990962) establishment of blood-retinal barrier(GO:1990963)
0.8 21.8 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.7 3.7 GO:0042701 progesterone secretion(GO:0042701)
0.7 33.3 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.7 3.5 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.6 3.9 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.5 3.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.4 1.2 GO:0032218 riboflavin transport(GO:0032218)
0.4 1.5 GO:0002084 protein depalmitoylation(GO:0002084)
0.4 1.1 GO:0021836 chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.4 3.9 GO:0046085 adenosine metabolic process(GO:0046085)
0.3 1.0 GO:0071454 cellular response to anoxia(GO:0071454)
0.3 2.5 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.3 3.4 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.3 1.4 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.3 3.7 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.2 0.7 GO:0030186 melatonin metabolic process(GO:0030186)
0.2 1.7 GO:0000103 sulfate assimilation(GO:0000103)
0.2 6.9 GO:0010107 potassium ion import(GO:0010107)
0.2 2.5 GO:0042118 endothelial cell activation(GO:0042118)
0.2 5.5 GO:0072311 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.2 5.7 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.2 2.3 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.2 4.4 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.2 1.7 GO:0071501 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 3.2 GO:0010842 retina layer formation(GO:0010842)
0.1 0.6 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223) DNA protection(GO:0042262)
0.1 0.4 GO:0001966 thigmotaxis(GO:0001966)
0.1 1.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.6 GO:0060005 vestibular reflex(GO:0060005)
0.1 1.5 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 1.0 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 1.1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 0.5 GO:0003383 apical constriction(GO:0003383)
0.1 5.6 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 4.3 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.1 1.7 GO:0032801 receptor catabolic process(GO:0032801)
0.1 1.3 GO:0006677 glycosylceramide metabolic process(GO:0006677)
0.1 0.6 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 5.6 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 0.7 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.3 GO:0010999 regulation of eIF2 alpha phosphorylation by heme(GO:0010999)
0.1 17.7 GO:0009755 hormone-mediated signaling pathway(GO:0009755)
0.1 0.2 GO:0072276 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277) response to formaldehyde(GO:1904404)
0.1 0.5 GO:0098885 modification of postsynaptic actin cytoskeleton(GO:0098885)
0.1 0.6 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.4 GO:0042148 strand invasion(GO:0042148)
0.1 0.8 GO:0051764 actin crosslink formation(GO:0051764)
0.0 1.0 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 1.3 GO:0006692 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 1.5 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.0 1.4 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 0.2 GO:0046836 glycolipid transport(GO:0046836)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338) regulation of IRE1-mediated unfolded protein response(GO:1903894)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 1.0 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 0.3 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.0 0.8 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.3 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.0 7.5 GO:0051260 protein homooligomerization(GO:0051260)
0.0 2.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 2.4 GO:0007050 cell cycle arrest(GO:0007050)
0.0 23.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.2 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.4 GO:0030728 ovulation(GO:0030728)
0.0 0.8 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.2 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 1.3 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.3 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.2 GO:2000678 negative regulation of transcription regulatory region DNA binding(GO:2000678)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 17.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
2.5 22.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.8 2.5 GO:0043511 inhibin complex(GO:0043511)
0.4 2.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.3 3.4 GO:0070187 telosome(GO:0070187)
0.3 0.8 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.3 5.4 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3 3.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 1.7 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.2 4.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 2.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 4.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 5.5 GO:0005801 cis-Golgi network(GO:0005801)
0.1 1.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 9.5 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.5 GO:0033269 internode region of axon(GO:0033269)
0.1 0.8 GO:0071439 clathrin complex(GO:0071439)
0.1 1.6 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.5 GO:0098871 postsynaptic actin cytoskeleton(GO:0098871) postsynaptic cytoskeleton(GO:0099571)
0.1 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 0.7 GO:0043202 lysosomal lumen(GO:0043202)
0.1 0.7 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 6.1 GO:0072562 blood microparticle(GO:0072562)
0.0 2.4 GO:0005902 microvillus(GO:0005902)
0.0 1.0 GO:0001741 XY body(GO:0001741)
0.0 65.3 GO:0005615 extracellular space(GO:0005615)
0.0 0.6 GO:0032426 stereocilium tip(GO:0032426)
0.0 1.1 GO:0030673 axolemma(GO:0030673)
0.0 1.0 GO:0097225 sperm midpiece(GO:0097225)
0.0 2.5 GO:0044438 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 1.2 GO:0046930 pore complex(GO:0046930)
0.0 0.8 GO:0005922 connexon complex(GO:0005922)
0.0 1.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 7.5 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.5 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 4.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 1.1 GO:0045095 keratin filament(GO:0045095)
0.0 1.3 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 5.3 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.0 GO:0044299 C-fiber(GO:0044299)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.5 22.5 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
5.5 16.5 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
3.6 18.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
1.4 5.4 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
1.1 4.4 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.9 7.2 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.8 17.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.7 21.8 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.7 3.3 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.6 3.2 GO:0005042 netrin receptor activity(GO:0005042)
0.6 2.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.5 8.6 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.4 2.8 GO:0004064 arylesterase activity(GO:0004064)
0.4 1.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.4 7.8 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.3 1.4 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.3 3.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.3 1.3 GO:0036132 13-prostaglandin reductase activity(GO:0036132)
0.3 35.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.3 6.9 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.3 2.3 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.3 3.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.3 0.8 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.3 1.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 1.0 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.2 2.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 2.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2 1.7 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.2 5.1 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) lamin binding(GO:0005521)
0.2 3.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 13.9 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 5.6 GO:0005109 frizzled binding(GO:0005109)
0.1 0.8 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 1.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 1.4 GO:0016805 dipeptidase activity(GO:0016805)
0.1 7.5 GO:0043621 protein self-association(GO:0043621)
0.1 1.0 GO:0008432 JUN kinase binding(GO:0008432)
0.1 3.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 3.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 1.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 1.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.4 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.4 GO:0000150 recombinase activity(GO:0000150)
0.1 0.3 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.2 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 1.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 1.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.6 GO:0047429 pyrimidine nucleotide binding(GO:0019103) deoxyribonucleotide binding(GO:0032552) nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 0.7 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.3 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.7 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.7 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 1.9 GO:0000049 tRNA binding(GO:0000049)
0.0 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.9 GO:0099589 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0 22.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.7 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)
0.0 0.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.6 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 3.9 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.0 1.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.4 GO:0017124 SH3 domain binding(GO:0017124)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 16.7 PID IGF1 PATHWAY IGF1 pathway
0.2 5.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 3.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.4 PID RAS PATHWAY Regulation of Ras family activation
0.0 2.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.7 PID P73PATHWAY p73 transcription factor network
0.0 1.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.8 PID FGF PATHWAY FGF signaling pathway
0.0 2.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 22.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.9 16.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.6 17.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.5 5.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.5 18.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.5 7.8 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.4 3.9 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.3 2.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 3.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 6.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 2.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 6.1 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 1.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 7.4 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 1.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.7 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 1.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction