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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Nanog

Z-value: 0.89

Motif logo

Transcription factors associated with Nanog

Gene Symbol Gene ID Gene Info
ENSRNOG00000008368 Nanog homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nanogrn6_v1_chr4_+_155531906_155531906-0.256.8e-06Click!

Activity profile of Nanog motif

Sorted Z-values of Nanog motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_9762813 32.00 ENSRNOT00000033749
solute carrier family 34 member 1
chr3_+_117421604 22.23 ENSRNOT00000008860
ENSRNOT00000008857
solute carrier family 12 member 1
chr13_+_44424689 20.64 ENSRNOT00000005206
aminocarboxymuconate semialdehyde decarboxylase
chr5_+_33784715 18.18 ENSRNOT00000035685
solute carrier family 7 member 13
chr10_+_49231730 17.00 ENSRNOT00000065335
tripartite motif-containing 16
chr17_+_69468427 16.45 ENSRNOT00000058413
similar to 20-alpha-hydroxysteroid dehydrogenase
chr1_-_224533219 14.80 ENSRNOT00000051289
integral membrane transport protein UST5r
chr7_+_29435444 14.51 ENSRNOT00000008613
solute carrier family 5 member 8
chr6_+_76349362 14.01 ENSRNOT00000043224
aldolase 1 A retrogene 2
chr20_+_26999795 13.61 ENSRNOT00000057872
myopalladin
chr9_-_26707571 12.13 ENSRNOT00000080948

chr10_+_75620470 11.81 ENSRNOT00000013882
coiled-coil domain containing 182
chr16_+_54319377 11.35 ENSRNOT00000090266
microtubule associated tumor suppressor 1
chr19_-_10450186 11.22 ENSRNOT00000088048
adhesion G protein-coupled receptor G1
chr18_+_29352749 11.05 ENSRNOT00000025137
solute carrier family 4 member 9
chr13_+_55274199 10.86 ENSRNOT00000029679
ATPase H+ transporting V1 subunit G3
chr18_-_69944632 9.93 ENSRNOT00000047271
mitogen-activated protein kinase 4
chr17_-_78735324 9.91 ENSRNOT00000036299
cerebral dopamine neurotrophic factor
chr1_-_216663720 9.64 ENSRNOT00000078944
ENSRNOT00000077409
cyclin-dependent kinase inhibitor 1C
chr16_-_48981980 9.61 ENSRNOT00000014235
acyl-CoA synthetase long-chain family member 1
chr1_+_177569618 9.57 ENSRNOT00000090042
TEA domain transcription factor 1
chr20_+_20236151 9.26 ENSRNOT00000079630
ankyrin 3
chr10_-_34333305 9.26 ENSRNOT00000071365
olfactory receptor gene Olr1384
chr13_+_99335020 9.05 ENSRNOT00000029787

chr15_+_51065316 8.95 ENSRNOT00000020753
NK3 homeobox 1
chr17_-_42031265 8.75 ENSRNOT00000068021
doublecortin domain containing 2
chr18_-_26656879 8.62 ENSRNOT00000086729
erythrocyte membrane protein band 4.1 like 4A
chrX_-_142164220 8.51 ENSRNOT00000064780
fibroblast growth factor 13
chr1_-_189238776 8.19 ENSRNOT00000020817
protein disulfide isomerase-like, testis expressed
chr12_-_44381289 8.04 ENSRNOT00000001493
nitric oxide synthase 1
chr14_-_19072677 8.01 ENSRNOT00000060548
similar to alpha-fetoprotein
chr16_-_31972507 7.90 ENSRNOT00000032199
carbonyl reductase 4
chr7_-_50638798 7.81 ENSRNOT00000048880
synaptotagmin 1
chr10_+_59799123 7.71 ENSRNOT00000026493
transient receptor potential cation channel, subfamily V, member 1
chr15_-_8989580 7.65 ENSRNOT00000061402
thyroid hormone receptor beta
chr8_-_40883880 7.59 ENSRNOT00000075593
disks large homolog 5-like
chr3_-_76496283 7.59 ENSRNOT00000044305
olfactory receptor 611
chr8_-_78233430 7.50 ENSRNOT00000083220
cingulin-like 1
chrM_+_11736 7.38 ENSRNOT00000048767
mitochondrially encoded NADH dehydrogenase 5
chr9_+_43259709 7.23 ENSRNOT00000022487
cytochrome c oxidase subunit 5B
chr8_-_128711221 7.18 ENSRNOT00000055888
xin actin-binding repeat containing 1
chr16_+_2706428 7.11 ENSRNOT00000077117
interleukin 17 receptor D
chr13_-_48927483 7.07 ENSRNOT00000010976
cyclin-dependent kinase 18
chr5_+_120340646 6.90 ENSRNOT00000086259
ENSRNOT00000086539
DnaJ heat shock protein family (Hsp40) member C6
chr8_-_115145810 6.86 ENSRNOT00000079470
abhydrolase domain containing 14A
chr10_+_85628491 6.85 ENSRNOT00000085000
ENSRNOT00000066899
CDGSH iron sulfur domain 3
chr14_+_77922045 6.84 ENSRNOT00000081198
serine/threonine kinase 32B
chr9_-_82336806 6.58 ENSRNOT00000024667
solute carrier family 23, member 3
chr4_-_22424862 6.50 ENSRNOT00000082359
ATP binding cassette subfamily B member 1A
chr4_-_82194927 6.49 ENSRNOT00000072302
homeobox protein Hox-A9
chr4_+_1355820 6.48 ENSRNOT00000072554
olfactory receptor 143-like
chr10_-_91661558 6.47 ENSRNOT00000043156

chr15_-_105402708 6.35 ENSRNOT00000057564
oxoglutarate receptor 1
chr4_+_174181644 6.29 ENSRNOT00000011555
capping actin protein of muscle Z-line alpha subunit 3
chr11_-_60251415 6.16 ENSRNOT00000080148
ENSRNOT00000086602
solute carrier family 9 member C1
chr14_+_71542057 6.13 ENSRNOT00000082592
ENSRNOT00000083701
ENSRNOT00000084322
prominin 1
chr4_+_68849033 6.12 ENSRNOT00000016912
maltase-glucoamylase
chr20_+_10123651 6.09 ENSRNOT00000001559
phosphodiesterase 9A
chr16_-_15798974 6.04 ENSRNOT00000046842
ENSRNOT00000065946
neuregulin 3
chr7_-_134722215 6.03 ENSRNOT00000036750
prickle planar cell polarity protein 1
chr1_+_65851060 5.99 ENSRNOT00000036880
zinc finger and SCAN domain containing 18
chr4_+_78168117 5.97 ENSRNOT00000010853
ATPase, H+ transporting V0 subunit e2
chr10_+_63677396 5.85 ENSRNOT00000005100
solute carrier family 43 member 2
chr7_-_3386522 5.78 ENSRNOT00000010760
methyltransferase like 7B
chr5_+_137546860 5.75 ENSRNOT00000074431
olfactory receptor 858
chrM_+_5323 5.62 ENSRNOT00000050156
mitochondrially encoded cytochrome c oxidase 1
chr1_+_213511874 5.54 ENSRNOT00000078080
ENSRNOT00000016883
cytochrome P450, family 2, subfamily e, polypeptide 1
chr1_+_215610368 5.43 ENSRNOT00000078903
ENSRNOT00000087781
troponin I2, fast skeletal type
chr1_+_80973739 5.34 ENSRNOT00000026088
ENSRNOT00000081983

chr17_+_43460782 5.30 ENSRNOT00000059494
solute carrier family 17, member 4
chr18_+_81694808 5.26 ENSRNOT00000020446
cytochrome b5 type A
chr8_+_42001912 5.23 ENSRNOT00000071709
olfactory receptor 1226
chr9_-_105693357 5.18 ENSRNOT00000066968
nudix hydrolase 12
chrX_+_13992064 5.17 ENSRNOT00000036543
rCG42854-like
chr16_-_47535358 5.13 ENSRNOT00000040731
claudin 22
chr10_-_89005213 5.08 ENSRNOT00000027159
PSMC3 interacting protein
chr2_-_231409988 5.03 ENSRNOT00000080637
ENSRNOT00000037255
ENSRNOT00000074002
ankyrin 2
chr10_-_65692016 5.00 ENSRNOT00000085074
ENSRNOT00000038690
solute carrier family 13 member 2
chr18_+_30592794 5.00 ENSRNOT00000027133
protocadherin beta 22
chrX_-_152110010 4.95 ENSRNOT00000044666
melanoma antigen family A, 5-like
chr10_+_53466870 4.93 ENSRNOT00000057503
phosphoinositide-interacting regulator of transient receptor potential channels
chr3_+_147511406 4.92 ENSRNOT00000082438
solute carrier family 52 member 3
chr20_+_4178686 4.87 ENSRNOT00000080641
testis specific basic protein
chr7_+_60015998 4.86 ENSRNOT00000007309
bestrophin 3
chr11_-_27971359 4.83 ENSRNOT00000085629
ENSRNOT00000051060
ENSRNOT00000042581
ENSRNOT00000050073
ENSRNOT00000081066
glutamate ionotropic receptor kainate type subunit 1
chr1_-_52495582 4.78 ENSRNOT00000067142
phosphodiesterase 10A
chr10_+_34402482 4.78 ENSRNOT00000072317
putative olfactory receptor
chr7_-_117289961 4.73 ENSRNOT00000042642
plectin
chr6_-_92121351 4.69 ENSRNOT00000006374
cyclin dependent kinase like 1
chr7_+_77066955 4.68 ENSRNOT00000008700
outer dense fiber of sperm tails 1
chr8_-_43854765 4.68 ENSRNOT00000081506
olfactory receptor 1335
chr3_+_73327828 4.65 ENSRNOT00000071299
similar to olfactory receptor Olr470
chr8_+_39687269 4.53 ENSRNOT00000012060
transmembrane protein 218
chr10_+_36466229 4.49 ENSRNOT00000004865
olfactory receptor 1404
chr1_+_60717386 4.49 ENSRNOT00000015019
protein phosphatase 2 scaffold subunit A alpha
chr19_-_24732024 4.48 ENSRNOT00000037608
trans-2,3-enoyl-CoA reductase
chr5_-_159119171 4.43 ENSRNOT00000074074
ENSRNOT00000075382
ENSRNOT00000074378
Rho guanine nucleotide exchange factor 10 like
chr3_+_75906945 4.42 ENSRNOT00000047110
olfactory receptor 586
chr1_+_247869756 4.42 ENSRNOT00000054764
melan-A
chr2_-_231409496 4.38 ENSRNOT00000055615
ENSRNOT00000015386
ENSRNOT00000068415
ankyrin 2
chrX_-_65335987 4.38 ENSRNOT00000047128

chr17_+_56935451 4.37 ENSRNOT00000058966
similar to hypothetical protein 4930474N05
chrX_+_77065397 4.30 ENSRNOT00000090007
cytochrome c oxidase subunit 7B
chr1_+_168575090 4.26 ENSRNOT00000048299
olfactory receptor 103
chr3_+_147511563 4.24 ENSRNOT00000006828
solute carrier family 52 member 3
chr16_+_54332660 4.20 ENSRNOT00000037685
microtubule associated tumor suppressor 1
chr1_-_7322424 4.16 ENSRNOT00000066725
ENSRNOT00000081112
zinc finger, C2HC-type containing 1B
chr4_-_727691 4.14 ENSRNOT00000008497
sonic hedgehog
chr8_+_55037750 4.11 ENSRNOT00000013188
translocase of inner mitochondrial membrane 8 homolog B
chr10_+_45297937 4.09 ENSRNOT00000066367
tripartite motif-containing 17
chr5_-_136098013 4.09 ENSRNOT00000089166
RGD1563714
chr5_-_17399801 4.07 ENSRNOT00000011900
similar to protein tyrosine phosphatase 4a2
chr1_-_169321075 4.06 ENSRNOT00000055216
similar to ubiquilin 1 isoform 2
chr9_-_74048244 4.06 ENSRNOT00000018293
LanC like 1
chr10_-_87248572 4.06 ENSRNOT00000066637
ENSRNOT00000085677
keratin 26
chr9_-_98551410 4.05 ENSRNOT00000066346
ENSRNOT00000086678
hes family bHLH transcription factor 6
chr11_+_76147205 4.01 ENSRNOT00000071586
fibroblast growth factor 12
chr1_-_206394346 3.98 ENSRNOT00000038122
hypothetical LOC100302465
chrX_+_33884499 3.98 ENSRNOT00000090041
RALBP1 associated Eps domain containing protein 2
chr15_-_52320385 3.96 ENSRNOT00000067776
dematin actin binding protein
chr2_-_250805445 3.94 ENSRNOT00000055362
chloride channel calcium activated 4-like
chr2_-_181874223 3.93 ENSRNOT00000035846
RNA binding motif protein 46
chr7_+_3630950 3.90 ENSRNOT00000074535
pre-mRNA-splicing factor CWC22 homolog
chr1_+_258074860 3.89 ENSRNOT00000054729
cytochrome P450, family 2, subfamily c, polypeptide 24
chr3_-_9738752 3.85 ENSRNOT00000045993
prostaglandin E synthase
chr20_+_31892515 3.85 ENSRNOT00000071394
tachykinin receptor 2
chr4_-_176909075 3.84 ENSRNOT00000067489
ATP binding cassette subfamily C member 9
chr6_+_8219385 3.84 ENSRNOT00000040509
protein phosphatase, Mg2+/Mn2+ dependent, 1B
chr1_+_212651917 3.83 ENSRNOT00000025635
olfactory receptor 287
chr13_+_71305548 3.83 ENSRNOT00000074864
similar to putative membrane protein Re9
chr8_+_62779875 3.82 ENSRNOT00000010831
cytochrome P450, family 11, subfamily a, polypeptide 1
chr15_-_9086282 3.82 ENSRNOT00000008989
thyroid hormone receptor beta
chr5_+_156026911 3.80 ENSRNOT00000046802
Rap1 GTPase-activating protein
chr5_-_101166651 3.77 ENSRNOT00000078862
Fras1 related extracellular matrix 1
chr10_-_60275762 3.77 ENSRNOT00000074380
olfactory receptor 1498
chr1_+_67025240 3.75 ENSRNOT00000051024
vomeronasal 1 receptor 47
chrX_-_23139694 3.74 ENSRNOT00000033656
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr7_+_63747577 3.65 ENSRNOT00000086123
ENSRNOT00000067395
ENSRNOT00000080052
RGD1561648
chr7_-_139929895 3.65 ENSRNOT00000047272
olfactory receptor 1104
chr17_+_90696019 3.64 ENSRNOT00000003438
G protein-coupled receptor 137B
chr14_+_34389991 3.63 ENSRNOT00000002953
phosducin-like 2
chr3_-_77227036 3.61 ENSRNOT00000072638
olfactory receptor 4P4-like
chr10_+_36517169 3.59 ENSRNOT00000040534
olfactory receptor 1408
chr8_-_55194692 3.57 ENSRNOT00000068366
similar to RIKEN cDNA 1110032A03
chrX_+_121612952 3.56 ENSRNOT00000022122

chr3_-_77826506 3.46 ENSRNOT00000071385
olfactory receptor 675
chr5_-_137617258 3.46 ENSRNOT00000071641
olfactory receptor 1330, pseudogene 1
chrM_+_9451 3.43 ENSRNOT00000041241
mitochondrially encoded NADH dehydrogenase 3
chr10_+_36485605 3.42 ENSRNOT00000048759
olfactory receptor 1406
chr7_-_130120579 3.42 ENSRNOT00000044376
mitogen-activated protein kinase 12
chr17_-_84830185 3.42 ENSRNOT00000040697
SKI/DACH domain containing 1
chrX_+_110789269 3.35 ENSRNOT00000086014
ring finger protein 128, E3 ubiquitin protein ligase
chr1_+_257970345 3.33 ENSRNOT00000088853
cytochrome P450, subfamily 2, polypeptide 11
chr3_+_75712483 3.31 ENSRNOT00000049264
olfactory receptor 575
chr3_-_44501115 3.29 ENSRNOT00000087071
activin A receptor type 1
chr1_-_67206713 3.22 ENSRNOT00000048195
vomeronasal 1 receptor 43
chr3_+_77261334 3.21 ENSRNOT00000049527
olfactory receptor 4C11-like
chr10_+_56824505 3.21 ENSRNOT00000067128
solute carrier family 16, member 11
chr7_+_117304742 3.16 ENSRNOT00000059599
glutamate ionotropic receptor NMDA type subunit associated protein 1
chr2_+_57276919 3.15 ENSRNOT00000063899
similar to hypothetical protein FLJ13231
chr1_+_85112247 3.10 ENSRNOT00000087157
dual specificity tyrosine phosphorylation regulated kinase 1B
chr2_-_165739874 3.07 ENSRNOT00000014384
karyopherin subunit alpha 4
chr3_+_75957592 3.04 ENSRNOT00000073455
olfactory receptor 590
chr3_-_102802338 3.03 ENSRNOT00000050334
olfactory receptor 768
chr8_+_117455262 3.01 ENSRNOT00000027520
solute carrier family 25 member 20
chr1_-_149633029 2.99 ENSRNOT00000048861
olfactory receptor 14A2-like
chr7_+_123531682 2.98 ENSRNOT00000010606
WBP2 N-terminal like
chr3_+_150761329 2.97 ENSRNOT00000067854
dynein light chain roadblock-type 1
chr3_+_48626038 2.94 ENSRNOT00000009697
grancalcin
chr11_-_1437732 2.93 ENSRNOT00000037345
casein kinase 2, alpha prime interacting protein
chr11_-_54344615 2.92 ENSRNOT00000090307
myosin, heavy chain 15
chr7_+_140032132 2.91 ENSRNOT00000014316
olfactory receptor 1107
chr2_-_195279218 2.89 ENSRNOT00000085565
similar to TDPOZ3
chr9_+_73528681 2.88 ENSRNOT00000084340
unc-80 homolog, NALCN activator
chr9_-_55673704 2.84 ENSRNOT00000066231
ENSRNOT00000081677
transmembrane protein with EGF-like and two follistatin-like domains 2
chr3_+_56125924 2.84 ENSRNOT00000011380
ubiquitin protein ligase E3 component n-recognin 3
chr1_-_255557055 2.83 ENSRNOT00000033780
fibroblast growth factor binding protein 3
chr4_+_57925323 2.82 ENSRNOT00000085798
carboxypeptidase A5
chr1_-_167588630 2.81 ENSRNOT00000050707
olfactory receptor 39
chr3_-_13865843 2.79 ENSRNOT00000025194
Rab9 effector protein with kelch motifs
chr7_-_58343137 2.75 ENSRNOT00000005310
ENSRNOT00000090560
transmembrane protein 19
chr3_+_114918648 2.74 ENSRNOT00000089204
sulfide quinone reductase-like (yeast)
chr7_-_54855557 2.74 ENSRNOT00000039475
GLI pathogenesis-related 1 like 1
chrX_+_123404518 2.74 ENSRNOT00000015085
solute carrier family 25 member 5
chr5_+_98387291 2.72 ENSRNOT00000046503
tyrosinase-related protein 1
chr5_+_64476317 2.72 ENSRNOT00000017217
collagen alpha-1(XV) chain-like
chr10_-_12312692 2.66 ENSRNOT00000073059
olfactory receptor 1355
chr3_-_75089064 2.66 ENSRNOT00000046167
olfactory receptor 542
chr7_-_6691679 2.64 ENSRNOT00000075430
olfactory receptor 959
chr7_-_13404858 2.64 ENSRNOT00000060456
olfactory receptor 1075
chrX_+_65796787 2.64 ENSRNOT00000076029
G protein-coupled receptor 165
chr1_-_170404056 2.62 ENSRNOT00000024402
amyloid beta precursor protein binding family B member 1
chr13_-_73704480 2.62 ENSRNOT00000005296
torsin 1A interacting protein 1
chr3_-_75235439 2.59 ENSRNOT00000046688
olfactory receptor 552
chr20_+_41266566 2.59 ENSRNOT00000000653
fyn-related Src family tyrosine kinase
chr1_-_104166367 2.58 ENSRNOT00000092211
cysteine and glycine rich protein 3
chr13_-_73704678 2.57 ENSRNOT00000005280
torsin 1A interacting protein 1
chr10_-_45940137 2.54 ENSRNOT00000004282
olfactory receptor 1463
chr7_+_139762614 2.53 ENSRNOT00000031157
coiled-coil domain containing 184
chr5_-_62260089 2.53 ENSRNOT00000064858
ENSRNOT00000011714
TBC1 domain family, member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Nanog

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
10.7 32.0 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
7.4 22.2 GO:0032978 protein insertion into membrane from inner side(GO:0032978)
3.4 20.6 GO:0046874 quinolinate metabolic process(GO:0046874)
3.1 9.2 GO:0032218 riboflavin transport(GO:0032218)
3.0 8.9 GO:0071899 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
2.8 17.0 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
2.6 7.7 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968) regulation of establishment of blood-brain barrier(GO:0090210)
2.4 9.4 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
2.3 9.3 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
2.0 8.0 GO:0098923 positive regulation of adrenergic receptor signaling pathway(GO:0071879) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
1.9 11.5 GO:0008050 female courtship behavior(GO:0008050)
1.8 7.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
1.8 8.9 GO:0016098 monoterpenoid metabolic process(GO:0016098)
1.7 5.2 GO:0019677 NADP catabolic process(GO:0006742) NAD catabolic process(GO:0019677)
1.7 6.9 GO:0072318 clathrin coat disassembly(GO:0072318)
1.6 6.5 GO:1905231 carbohydrate export(GO:0033231) daunorubicin transport(GO:0043215) response to borneol(GO:1905230) cellular response to borneol(GO:1905231) response to codeine(GO:1905233) response to quercetin(GO:1905235) drug transport across blood-brain barrier(GO:1990962) establishment of blood-retinal barrier(GO:1990963)
1.6 9.6 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
1.5 6.1 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
1.5 6.0 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
1.4 9.8 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
1.4 4.1 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
1.3 3.8 GO:1990792 response to glial cell derived neurotrophic factor(GO:1990790) cellular response to glial cell derived neurotrophic factor(GO:1990792)
1.1 13.6 GO:0048739 cardiac muscle fiber development(GO:0048739)
1.1 3.3 GO:0061443 endocardial cushion cell differentiation(GO:0061443)
1.0 4.0 GO:0070560 protein secretion by platelet(GO:0070560)
1.0 7.9 GO:0044598 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
1.0 3.8 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
1.0 9.6 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.9 2.8 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
0.9 4.5 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.9 11.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.9 2.6 GO:0035995 detection of muscle stretch(GO:0035995) regulation of actin filament severing(GO:1903918) negative regulation of actin filament severing(GO:1903919)
0.8 10.9 GO:0046069 cGMP catabolic process(GO:0046069)
0.8 2.5 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.8 4.0 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.8 3.8 GO:0060327 cytoplasmic actin-based contraction involved in cell motility(GO:0060327)
0.8 3.8 GO:0060014 granulosa cell differentiation(GO:0060014)
0.8 3.0 GO:0015879 carnitine transport(GO:0015879)
0.7 5.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.7 9.6 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.7 2.1 GO:0034241 positive regulation of macrophage fusion(GO:0034241)
0.7 2.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) protein K33-linked deubiquitination(GO:1990168)
0.7 2.7 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.7 6.0 GO:0051890 regulation of cardioblast differentiation(GO:0051890)
0.7 2.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.6 8.5 GO:0097369 sodium ion import(GO:0097369)
0.6 4.8 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.6 3.6 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.6 2.4 GO:0050904 Kit signaling pathway(GO:0038109) diapedesis(GO:0050904)
0.6 1.8 GO:0048749 compound eye development(GO:0048749)
0.6 8.2 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.6 22.1 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.6 1.7 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.6 7.8 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.5 5.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.5 2.0 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.5 2.9 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.5 2.8 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.5 3.7 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.5 14.3 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.5 3.6 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.5 3.2 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.4 1.3 GO:0010986 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986) positive regulation of cytolysis(GO:0045919) cellular response to iron(II) ion(GO:0071282)
0.4 1.3 GO:1902071 positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.4 1.3 GO:0006543 glutamine catabolic process(GO:0006543)
0.4 4.4 GO:0032933 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.4 1.1 GO:0045054 constitutive secretory pathway(GO:0045054)
0.4 0.7 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.3 1.4 GO:0000101 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.3 11.1 GO:0015701 bicarbonate transport(GO:0015701)
0.3 2.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.3 2.7 GO:0015866 ADP transport(GO:0015866)
0.3 4.5 GO:0030497 fatty acid elongation(GO:0030497)
0.3 3.0 GO:0007343 egg activation(GO:0007343)
0.3 1.7 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.3 2.3 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.3 2.8 GO:0042048 olfactory behavior(GO:0042048)
0.3 8.8 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.3 9.9 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.3 6.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.2 2.5 GO:0000338 protein deneddylation(GO:0000338)
0.2 4.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 3.9 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.2 5.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.2 1.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.2 2.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 21.1 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.2 3.8 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.2 1.5 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2 0.9 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
0.2 4.9 GO:0048266 behavioral response to pain(GO:0048266)
0.2 0.7 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.2 227.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.2 4.4 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.2 3.0 GO:0008090 retrograde axonal transport(GO:0008090)
0.2 0.5 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.2 3.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 7.7 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.2 7.2 GO:0045214 sarcomere organization(GO:0045214)
0.2 1.7 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.2 1.1 GO:0002248 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.2 4.0 GO:0031572 mitotic G2 DNA damage checkpoint(GO:0007095) G2 DNA damage checkpoint(GO:0031572)
0.2 1.4 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.2 1.4 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 0.9 GO:2000323 regulation of type B pancreatic cell development(GO:2000074) negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 3.8 GO:0002544 chronic inflammatory response(GO:0002544)
0.1 4.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 2.0 GO:0009642 response to light intensity(GO:0009642)
0.1 3.0 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.1 5.4 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 3.3 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.1 2.0 GO:0048484 enteric nervous system development(GO:0048484)
0.1 9.6 GO:0006096 glycolytic process(GO:0006096)
0.1 0.6 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 1.0 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 1.6 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.1 2.8 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.5 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 0.7 GO:0035989 tendon development(GO:0035989)
0.1 5.3 GO:0046686 response to cadmium ion(GO:0046686)
0.1 2.5 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.1 0.5 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 2.0 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 2.7 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.1 0.9 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 0.3 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.1 0.8 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 0.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 1.0 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 13.7 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.1 2.6 GO:0010039 response to iron ion(GO:0010039)
0.1 4.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 0.2 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 10.4 GO:0098656 anion transmembrane transport(GO:0098656)
0.1 0.1 GO:0014901 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.1 0.6 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 1.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 3.4 GO:0045445 myoblast differentiation(GO:0045445)
0.0 2.5 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 2.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.4 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.4 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.9 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.4 GO:1990001 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341) inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.6 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.4 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.2 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 1.9 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.5 GO:0030157 pancreatic juice secretion(GO:0030157)
0.0 1.0 GO:0032543 mitochondrial translation(GO:0032543)
0.0 4.5 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 2.2 GO:0034968 histone lysine methylation(GO:0034968)
0.0 2.2 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 2.0 GO:0007416 synapse assembly(GO:0007416)
0.0 0.7 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.6 GO:0071148 TEAD-1-YAP complex(GO:0071148)
2.8 11.2 GO:0097451 glial limiting end-foot(GO:0097451)
1.5 6.1 GO:0071914 prominosome(GO:0071914)
1.3 13.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
1.3 7.8 GO:0042584 chromaffin granule membrane(GO:0042584)
1.0 6.0 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
1.0 3.8 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
1.0 17.2 GO:0045277 respiratory chain complex IV(GO:0045277)
0.8 4.8 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.7 3.3 GO:0048179 activin receptor complex(GO:0048179)
0.7 2.6 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.6 10.9 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.6 6.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.6 8.8 GO:0060091 kinocilium(GO:0060091)
0.5 7.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.5 6.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.5 2.7 GO:0071817 MMXD complex(GO:0071817)
0.5 5.4 GO:0005861 troponin complex(GO:0005861)
0.4 8.0 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.4 3.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.4 7.2 GO:0005916 fascia adherens(GO:0005916)
0.4 32.0 GO:0031526 brush border membrane(GO:0031526)
0.4 14.1 GO:0043034 costamere(GO:0043034)
0.3 2.7 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 4.7 GO:0001520 outer dense fiber(GO:0001520)
0.2 4.1 GO:0030061 mitochondrial crista(GO:0030061)
0.2 0.7 GO:0005592 collagen type XI trimer(GO:0005592)
0.2 10.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 10.8 GO:0014704 intercalated disc(GO:0014704)
0.2 1.4 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.2 2.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.2 17.6 GO:0016605 PML body(GO:0016605)
0.2 4.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 0.9 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 1.7 GO:0030008 TRAPP complex(GO:0030008)
0.1 4.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 7.9 GO:1990204 oxidoreductase complex(GO:1990204)
0.1 2.0 GO:0043194 axon initial segment(GO:0043194)
0.1 3.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 4.2 GO:0035869 ciliary transition zone(GO:0035869)
0.1 0.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 7.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 3.8 GO:0008180 COP9 signalosome(GO:0008180)
0.1 4.6 GO:0016459 myosin complex(GO:0016459)
0.1 1.0 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 2.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.7 GO:0044305 calyx of Held(GO:0044305)
0.1 12.1 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.1 4.9 GO:0034707 chloride channel complex(GO:0034707)
0.1 32.2 GO:0045177 apical part of cell(GO:0045177)
0.1 8.6 GO:0030018 Z disc(GO:0030018)
0.1 0.5 GO:0032280 symmetric synapse(GO:0032280)
0.1 6.1 GO:0032587 ruffle membrane(GO:0032587)
0.1 8.9 GO:0031514 motile cilium(GO:0031514)
0.1 0.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 1.8 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 0.2 GO:0008091 spectrin(GO:0008091)
0.1 3.9 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 4.3 GO:0000502 proteasome complex(GO:0000502)
0.1 0.6 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 1.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 2.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.9 GO:0016234 inclusion body(GO:0016234)
0.0 3.6 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.7 GO:0005581 collagen trimer(GO:0005581)
0.0 2.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 16.7 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 2.8 GO:0010008 endosome membrane(GO:0010008)
0.0 2.3 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.9 GO:0005643 nuclear pore(GO:0005643)
0.0 0.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 4.0 GO:0031965 nuclear membrane(GO:0031965)
0.0 2.2 GO:0043204 perikaryon(GO:0043204)
0.0 1.3 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.6 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.4 GO:0071565 nBAF complex(GO:0071565)
0.0 6.1 GO:0014069 postsynaptic density(GO:0014069)
0.0 4.9 GO:0005769 early endosome(GO:0005769)
0.0 124.9 GO:0016021 integral component of membrane(GO:0016021)
0.0 4.9 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 8.1 GO:0005794 Golgi apparatus(GO:0005794)
0.0 1.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 4.8 GO:0044429 mitochondrial part(GO:0044429)
0.0 0.3 GO:0030016 myofibril(GO:0030016)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.4 22.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
6.4 32.0 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
3.1 9.2 GO:0032217 riboflavin transporter activity(GO:0032217)
2.6 7.9 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
2.6 7.7 GO:0097603 temperature-gated ion channel activity(GO:0097603)
2.4 9.6 GO:0003987 acetate-CoA ligase activity(GO:0003987)
2.0 14.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.6 8.0 GO:0004517 nitric-oxide synthase activity(GO:0004517)
1.6 7.8 GO:0030348 syntaxin-3 binding(GO:0030348)
1.5 6.1 GO:0016160 amylase activity(GO:0016160)
1.4 17.0 GO:0019966 interleukin-1 binding(GO:0019966)
1.3 6.5 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
1.3 5.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
1.3 3.8 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
1.3 3.8 GO:0004995 tachykinin receptor activity(GO:0004995)
1.3 3.8 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
1.3 3.8 GO:0008281 sulfonylurea receptor activity(GO:0008281)
1.2 10.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
1.0 11.5 GO:0004887 thyroid hormone receptor activity(GO:0004887)
1.0 8.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
1.0 3.0 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.9 8.9 GO:0030284 estrogen receptor activity(GO:0030284)
0.9 7.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.9 13.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.8 11.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.8 10.9 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.8 5.4 GO:0031014 troponin T binding(GO:0031014)
0.8 5.3 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.7 5.1 GO:0050692 DBD domain binding(GO:0050692)
0.7 4.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.7 2.7 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.6 2.6 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.6 3.8 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.6 6.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.6 17.2 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.5 3.3 GO:0016361 activin receptor activity, type I(GO:0016361)
0.5 3.7 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.5 4.1 GO:0043237 laminin-1 binding(GO:0043237)
0.5 6.0 GO:0045499 chemorepellent activity(GO:0045499)
0.5 14.1 GO:0004707 MAP kinase activity(GO:0004707)
0.5 2.4 GO:0004969 histamine receptor activity(GO:0004969)
0.5 21.2 GO:0016831 carboxy-lyase activity(GO:0016831)
0.5 22.6 GO:0030507 spectrin binding(GO:0030507)
0.5 1.4 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.5 3.6 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.4 1.7 GO:1903135 cupric ion binding(GO:1903135)
0.4 12.8 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.4 34.3 GO:0015297 antiporter activity(GO:0015297)
0.4 10.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.4 2.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.4 6.0 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442)
0.4 10.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.4 1.4 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.3 6.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.3 13.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.3 3.0 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.3 5.2 GO:0005521 lamin binding(GO:0005521)
0.3 5.4 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.3 1.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.3 2.1 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.3 10.1 GO:0042805 actinin binding(GO:0042805)
0.3 1.8 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.2 1.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 4.1 GO:0043295 glutathione binding(GO:0043295)
0.2 5.3 GO:0009055 electron carrier activity(GO:0009055)
0.2 2.0 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2 1.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.2 0.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 2.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.2 2.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 227.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.2 6.3 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.2 0.5 GO:1990763 arrestin family protein binding(GO:1990763)
0.2 3.6 GO:0005112 Notch binding(GO:0005112)
0.2 4.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 8.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 2.5 GO:0097602 cullin family protein binding(GO:0097602)
0.1 14.0 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 2.6 GO:0048156 tau protein binding(GO:0048156)
0.1 8.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 2.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 2.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.3 GO:0016015 morphogen activity(GO:0016015)
0.1 3.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 3.0 GO:0050699 WW domain binding(GO:0050699)
0.1 2.1 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 1.9 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 3.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 5.0 GO:0005254 chloride channel activity(GO:0005254)
0.1 1.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 4.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 1.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 2.2 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.3 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.3 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 2.5 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.7 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 2.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 1.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.6 GO:0015288 porin activity(GO:0015288)
0.0 1.5 GO:0000049 tRNA binding(GO:0000049)
0.0 6.2 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.3 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 2.2 GO:0030674 protein binding, bridging(GO:0030674)
0.0 1.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 2.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 4.3 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.9 GO:0070888 E-box binding(GO:0070888)
0.0 1.1 GO:0019003 GDP binding(GO:0019003)
0.0 0.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.6 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 0.5 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.6 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.3 PID ALK2 PATHWAY ALK2 signaling events
0.3 12.0 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.3 11.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 13.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 7.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 2.1 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 6.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 7.1 PID FGF PATHWAY FGF signaling pathway
0.1 5.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 1.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 3.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 3.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 1.7 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 2.6 PID ATR PATHWAY ATR signaling pathway
0.1 1.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 2.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.5 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.7 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 0.4 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 4.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 20.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
1.8 5.5 REACTOME XENOBIOTICS Genes involved in Xenobiotics
1.0 6.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
1.0 9.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.8 89.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.6 17.7 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.6 7.8 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.5 2.7 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.4 10.9 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.3 11.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 4.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.3 4.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.3 6.9 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.3 4.5 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.3 7.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 3.4 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.2 3.8 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.2 3.8 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.2 4.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 11.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.2 5.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 1.8 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 5.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.2 3.0 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 5.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 0.7 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 2.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 3.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 0.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 2.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 6.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 5.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 2.3 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.1 2.9 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 1.1 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.1 7.1 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.1 1.1 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 2.4 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 4.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 2.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis