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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Mzf1

Z-value: 0.63

Motif logo

Transcription factors associated with Mzf1

Gene Symbol Gene ID Gene Info
ENSRNOG00000027550 myeloid zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mzf1rn6_v1_chr1_+_65522118_65522118-0.131.7e-02Click!

Activity profile of Mzf1 motif

Sorted Z-values of Mzf1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_70072156 17.51 ENSRNOT00000046667
calmodulin-like 3
chr5_-_24631679 12.79 ENSRNOT00000010846
ENSRNOT00000067129
epithelial splicing regulatory protein 1
chr2_+_206064179 11.57 ENSRNOT00000025953
synaptotagmin 6
chr7_+_70364813 11.41 ENSRNOT00000084012
ENSRNOT00000031230
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr2_+_206064394 11.17 ENSRNOT00000077739
synaptotagmin 6
chr1_+_144831523 10.77 ENSRNOT00000039748
mex-3 RNA binding family member B
chr5_+_154522119 10.27 ENSRNOT00000072618
E2F transcription factor 2
chr17_+_43627930 10.16 ENSRNOT00000081719
histone H2B type 1-N-like
chr8_+_47674321 9.97 ENSRNOT00000026170
ENSRNOT00000078776
tripartite motif-containing 29
chr19_+_54060622 8.83 ENSRNOT00000023607
Gse1 coiled-coil protein
chr3_+_16753703 8.51 ENSRNOT00000077741

chr7_+_142912316 8.41 ENSRNOT00000010171
nuclear receptor subfamily 4, group A, member 1
chr1_+_82480195 8.08 ENSRNOT00000028051
transforming growth factor, beta 1
chr7_-_70969905 8.04 ENSRNOT00000057745
Ngfi-A binding protein 2
chr12_-_9331195 8.01 ENSRNOT00000044134
PAN3 poly(A) specific ribonuclease subunit
chr2_+_188495629 8.01 ENSRNOT00000027828
family with sequence similarity 189, member B
chr3_-_148722710 7.80 ENSRNOT00000090919
ENSRNOT00000068592
PLAG1 like zinc finger 2
chr2_-_207300854 7.29 ENSRNOT00000018061
Mov10 RISC complex RNA helicase
chr20_+_5527181 7.07 ENSRNOT00000091364
PHD finger protein 1
chr3_+_124068865 6.61 ENSRNOT00000079264
spermine oxidase
chr20_+_46429222 6.38 ENSRNOT00000076818
forkhead box O3
chr10_+_97212432 6.22 ENSRNOT00000088599
axin 2
chr20_+_6923489 6.19 ENSRNOT00000093373
ENSRNOT00000000632
peptidase inhibitor 16
chr3_-_7795758 6.10 ENSRNOT00000045919
netrin G2
chr3_-_150064438 5.94 ENSRNOT00000086933
E2F transcription factor 1
chr5_-_151977636 5.73 ENSRNOT00000009173
AT-rich interaction domain 1A
chr2_-_219458271 5.65 ENSRNOT00000064735
cell division cycle 14A
chr20_+_5374985 5.63 ENSRNOT00000052270
RT1 class Ia, locus A2
chr10_+_94280703 5.59 ENSRNOT00000088656
mitogen activated protein kinase kinase kinase 3
chr6_-_21600451 5.36 ENSRNOT00000047674
latent transforming growth factor beta binding protein 1
chr2_+_196334626 5.27 ENSRNOT00000050914
ENSRNOT00000028645
ENSRNOT00000090729
semaphorin 6C
chr7_+_119482272 5.18 ENSRNOT00000009544
neutrophil cytosolic factor 4
chr10_-_56154548 5.04 ENSRNOT00000090809
dynein, axonemal, heavy chain 2
chr4_-_115157263 4.77 ENSRNOT00000015296
tet methylcytosine dioxygenase 3
chr15_+_33555640 4.77 ENSRNOT00000021096
poly(A) binding protein, nuclear 1
chr11_-_65209268 4.76 ENSRNOT00000077612
glycogen synthase kinase 3 beta
chr19_+_26142720 4.72 ENSRNOT00000005270
similar to RIKEN cDNA 2310036O22
chr20_-_1818800 4.70 ENSRNOT00000000990
RT1 class Ib, locus M3, gene 1
chr1_+_80000165 4.69 ENSRNOT00000084912
SIX homeobox 5
chr4_+_102665529 4.61 ENSRNOT00000082333

chr14_+_108007724 4.46 ENSRNOT00000014062
exportin 1
chr20_-_5140304 4.44 ENSRNOT00000092646
proline-rich coiled-coil 2A
chr12_+_46615649 4.41 ENSRNOT00000086531
ENSRNOT00000089494
BICD family like cargo adaptor 1
chr4_-_82300503 4.36 ENSRNOT00000071568
homeobox A11
chr9_+_81518584 4.30 ENSRNOT00000084309
actin related protein 2/3 complex, subunit 2
chr10_-_64862268 4.28 ENSRNOT00000056234
PHD finger protein 12
chr1_+_198214797 4.03 ENSRNOT00000068543
T-box 6
chr10_+_56591292 4.02 ENSRNOT00000023379
CTD nuclear envelope phosphatase 1
chr17_-_54808483 3.98 ENSRNOT00000075683

chr12_+_21721837 3.97 ENSRNOT00000073353
methylphosphate capping enzyme
chr15_-_45927804 3.93 ENSRNOT00000086271
integrator complex subunit 6
chr4_+_82214342 3.57 ENSRNOT00000066360
homeobox A11, opposite strand
chr3_-_156340913 3.53 ENSRNOT00000021452
MAF bZIP transcription factor B
chr12_-_21760292 3.49 ENSRNOT00000059592
TSC22 domain family protein 4-like
chr2_-_196415530 3.45 ENSRNOT00000064238
similar to hypothetical protein FLJ20519
chr9_+_82033543 3.44 ENSRNOT00000023439
wingless-type MMTV integration site family, member 6
chr4_+_8256611 3.43 ENSRNOT00000061894

chr6_+_109300433 3.42 ENSRNOT00000010712
FBJ osteosarcoma oncogene
chr1_+_72636959 3.36 ENSRNOT00000023489
interleukin 11
chr7_-_144880092 3.35 ENSRNOT00000055281
nuclear factor, erythroid 2
chr3_-_119135391 3.34 ENSRNOT00000045443
GA binding protein transcription factor, beta subunit 1
chr2_+_113984646 3.23 ENSRNOT00000016799
TRAF2 and NCK interacting kinase
chr10_-_85124644 3.21 ENSRNOT00000012376
karyopherin subunit beta 1
chr4_-_152835182 3.20 ENSRNOT00000036721
beta-1,4-N-acetyl-galactosaminyl transferase 3
chr13_-_41738622 3.15 ENSRNOT00000004520
ENSRNOT00000084552
ARP3 actin related protein 3 homolog
chr20_+_4993560 3.14 ENSRNOT00000081628
ENSRNOT00000087861
ENSRNOT00000001160
valyl-tRNA synthetase
chr6_+_132702448 3.12 ENSRNOT00000005743
YY1 transcription factor
chr14_-_35652709 3.04 ENSRNOT00000003080
GS homeobox 2
chr2_+_210381829 3.03 ENSRNOT00000024611
ALX homeobox 3
chr2_+_205160405 2.97 ENSRNOT00000035605
tetraspanin 2
chr1_+_183892841 2.91 ENSRNOT00000015498
phosphodiesterase 3B
chr10_-_56591364 2.81 ENSRNOT00000032481
elongator acetyltransferase complex subunit 5
chr3_-_46051096 2.80 ENSRNOT00000081302
bromodomain adjacent to zinc finger domain, 2B
chr13_+_51126459 2.74 ENSRNOT00000042046
ENSRNOT00000087240
myogenin
chr10_+_68588789 2.69 ENSRNOT00000049614

chr7_-_3074359 2.53 ENSRNOT00000019738
IKAROS family zinc finger 4
chr8_-_111850075 2.51 ENSRNOT00000082097
CDV3 homolog
chr10_-_110182291 2.48 ENSRNOT00000015178
ENSRNOT00000054936
casein kinase 1, delta
chr5_+_144160108 2.45 ENSRNOT00000064972
eva-1 homolog B
chr10_+_56627411 2.39 ENSRNOT00000089108
ENSRNOT00000068493
discs large MAGUK scaffold protein 4
chr1_-_52894832 2.34 ENSRNOT00000016471
T brachyury transcription factor
chr4_+_145017608 2.33 ENSRNOT00000066723
SET domain containing 5
chr3_+_170550314 2.32 ENSRNOT00000006991
transcription factor AP-2 gamma
chr2_-_208152179 2.31 ENSRNOT00000068152
DEAD-box helicase 20
chrX_-_1856258 2.25 ENSRNOT00000079980
similar to RuvB-like protein 1
chr1_-_154216340 2.23 ENSRNOT00000024082
embryonic ectoderm development
chr13_-_45040593 2.17 ENSRNOT00000004908
lactase
chr1_-_101388125 2.14 ENSRNOT00000028176
ENSRNOT00000049957
small nuclear ribonucleoprotein U1 subunit 70
chr18_+_65814026 2.13 ENSRNOT00000016112
methyl-CpG binding domain protein 2
chr10_+_86860685 2.10 ENSRNOT00000084644
retinoic acid receptor, alpha
chr5_+_147476221 2.04 ENSRNOT00000010730
syncoilin, intermediate filament protein
chr12_-_21728678 2.01 ENSRNOT00000035372
protein phosphatase 1 regulatory subunit 35-like
chr9_+_16612433 2.00 ENSRNOT00000023979
kelch domain containing 3
chr10_+_86157608 1.98 ENSRNOT00000082668
ENSRNOT00000008256
cyclin-dependent kinase 12
chr17_+_36334589 1.97 ENSRNOT00000081368
E2F transcription factor 3
chr3_+_112228919 1.95 ENSRNOT00000011761
calpain 3
chr6_+_10533151 1.94 ENSRNOT00000020822
ras homolog family member Q
chr12_+_40510378 1.93 ENSRNOT00000001817
mitogen-activated protein kinase-activated protein kinase 5
chr2_-_46544457 1.90 ENSRNOT00000015680
follistatin
chr6_+_128973956 1.90 ENSRNOT00000075399
family with sequence similarity 181, member A
chr7_-_140546908 1.85 ENSRNOT00000077502
lysine methyltransferase 2D
chr18_-_6474990 1.81 ENSRNOT00000061504
potassium channel tetramerization domain containing 1
chr15_+_23665202 1.78 ENSRNOT00000089226
sterile alpha motif domain containing 4A
chr10_-_64657089 1.77 ENSRNOT00000080703
active BCR-related
chr5_-_50221095 1.76 ENSRNOT00000012164
similar to hypothetical protein
chr14_-_86868598 1.76 ENSRNOT00000087212
NAC alpha domain containing
chr3_-_8659102 1.74 ENSRNOT00000050908
zinc finger, DHHC-type containing 12
chr1_+_278198179 1.71 ENSRNOT00000023247
family with sequence similarity 160, member B1
chr3_+_112228720 1.70 ENSRNOT00000079079
calpain 3
chr4_-_118472179 1.69 ENSRNOT00000023856
max dimerization protein 1
chr15_-_52210746 1.68 ENSRNOT00000046054
bone morphogenetic protein 1
chr1_+_197999037 1.65 ENSRNOT00000091065
apolipoprotein B receptor
chr6_+_108831108 1.65 ENSRNOT00000038594
U6 snRNA-associated Sm-like protein LSm5 pseudogene
chr1_+_44446765 1.61 ENSRNOT00000030132
claudin 20
chr15_+_12827707 1.61 ENSRNOT00000012452
Fez family zinc finger 2
chr4_-_57625147 1.60 ENSRNOT00000074649
ENSRNOT00000078961
ubiquitin-conjugating enzyme E2H
chr10_-_56365084 1.53 ENSRNOT00000068013
RNA polymerase II subunit A
chr4_+_98648545 1.52 ENSRNOT00000008451
eukaryotic translation initiation factor 2 alpha kinase 3
chr1_-_72377434 1.51 ENSRNOT00000022193
zinc finger protein 524
chr5_+_140979435 1.51 ENSRNOT00000056592
poly(A) binding protein, cytoplasmic 4
chr1_+_199225100 1.50 ENSRNOT00000088606
SET domain containing 1A
chr1_+_197999336 1.46 ENSRNOT00000023555
apolipoprotein B receptor
chr5_-_146069670 1.44 ENSRNOT00000072793
hypothetical protein LOC682102
chr4_-_56114254 1.40 ENSRNOT00000010673
leucine rich repeat containing 4
chr8_-_63291966 1.40 ENSRNOT00000077762

chr5_-_144556889 1.37 ENSRNOT00000035373
argonaute 4, RISC catalytic component
chr12_+_22229079 1.36 ENSRNOT00000001911
G protein subunit beta 2
chr15_+_26033791 1.30 ENSRNOT00000020074
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr8_+_48805684 1.29 ENSRNOT00000064041
B-cell CLL/lymphoma 9-like
chr7_+_142869752 1.25 ENSRNOT00000009979
general receptor for phosphoinositides 1 associated scaffold protein
chr20_-_1984737 1.23 ENSRNOT00000040232
ENSRNOT00000051634
ENSRNOT00000079445
gamma-aminobutyric acid type B receptor subunit 1
chr3_-_57119001 1.19 ENSRNOT00000083171
tousled-like kinase 1
chr2_+_188844073 1.18 ENSRNOT00000028117
potassium calcium-activated channel subfamily N member 3
chr10_-_56444847 1.12 ENSRNOT00000056872
ENSRNOT00000092662
neuroligin 2
chr4_+_159622404 1.11 ENSRNOT00000078299
fibroblast growth factor 23
chr1_+_280633938 1.09 ENSRNOT00000012564
empty spiracles homeobox 2
chr5_-_59085676 1.08 ENSRNOT00000068105
microseminoprotein, prostate associated
chr15_-_12513931 1.08 ENSRNOT00000010103
ataxin 7
chr18_+_30890869 1.08 ENSRNOT00000060466
protocadherin gamma subfamily B, 6
chr1_+_87180624 0.92 ENSRNOT00000056933
ENSRNOT00000027987
protein YIF1B
chr10_-_85684138 0.90 ENSRNOT00000017989
phosphatidylinositol-5-phosphate 4-kinase type 2 beta
chr16_-_36373546 0.89 ENSRNOT00000079552
heart and neural crest derivatives expressed transcript 2
chr9_+_82596355 0.88 ENSRNOT00000065076
SPEG complex locus
chr2_-_77632628 0.86 ENSRNOT00000073915
brain abundant, membrane attached signal protein 1
chr2_+_198762138 0.84 ENSRNOT00000028811
peroxisomal biogenesis factor 11 beta
chrX_-_157095274 0.84 ENSRNOT00000084088
ATP binding cassette subfamily D member 1
chr4_+_66290389 0.82 ENSRNOT00000008557
LUC7-like 2 pre-mRNA splicing factor
chr10_-_86144880 0.80 ENSRNOT00000067901
mediator complex subunit 1
chr20_-_1980101 0.76 ENSRNOT00000084582
ENSRNOT00000085050
ENSRNOT00000082545
ENSRNOT00000088396
gamma-aminobutyric acid type B receptor subunit 1
chr9_-_10991820 0.76 ENSRNOT00000073011
ENSRNOT00000081441
hepatoma-derived growth factor-related protein 2
chr5_-_58113553 0.74 ENSRNOT00000046589
AT-rich interaction domain 3C
chrX_-_63204530 0.73 ENSRNOT00000076175
zinc finger protein X-linked
chr9_+_20264418 0.71 ENSRNOT00000051841
atrophin 1
chr7_-_36499784 0.70 ENSRNOT00000011948
suppressor of cytokine signaling 2
chr2_-_199354793 0.66 ENSRNOT00000023548
B-cell CLL/lymphoma 9
chr10_+_84200880 0.64 ENSRNOT00000011213
homeobox B2
chr7_-_140454268 0.62 ENSRNOT00000081468
wingless-type MMTV integration site family, member 10B
chr10_-_65963932 0.62 ENSRNOT00000011726
nemo like kinase
chr6_+_98284170 0.60 ENSRNOT00000031979
ras homolog family member J
chr7_+_58366192 0.60 ENSRNOT00000081891
zinc finger, C3H1-type containing
chr20_-_6961162 0.57 ENSRNOT00000000635
mitochondrial carrier 1
chr2_+_113984824 0.55 ENSRNOT00000086399
TRAF2 and NCK interacting kinase
chr10_-_85574889 0.55 ENSRNOT00000072274
hypothetical protein LOC691153
chr20_+_5050327 0.49 ENSRNOT00000083353
dimethylarginine dimethylaminohydrolase 2
chr17_-_27665266 0.49 ENSRNOT00000060218
ras responsive element binding protein 1
chr5_+_59080765 0.47 ENSRNOT00000021888
ENSRNOT00000064419
RGP1 homolog, RAB6A GEF complex partner 1
chr1_-_199865548 0.45 ENSRNOT00000027463
Tia1 cytotoxic granule-associated RNA binding protein-like 1
chr2_-_198719202 0.36 ENSRNOT00000028801
RNA polymerase III subunit G like
chr4_-_155116154 0.28 ENSRNOT00000020529
polyhomeotic homolog 1
chr2_+_188748359 0.25 ENSRNOT00000028038
SHC adaptor protein 1
chr17_-_90217786 0.25 ENSRNOT00000073534
inositol monophosphatase domain containing 1
chr7_+_25919867 0.24 ENSRNOT00000009625
ENSRNOT00000090153
RIC8 guanine nucleotide exchange factor B
chr20_-_1099336 0.21 ENSRNOT00000071766
olfactory receptor-like protein-like
chr11_-_83926524 0.16 ENSRNOT00000041777
ENSRNOT00000040029
eukaryotic translation initiation factor 4 gamma, 1
chr3_+_7279340 0.16 ENSRNOT00000017029
adenylate kinase 8
chr5_+_169338097 0.13 ENSRNOT00000014035
hes family bHLH transcription factor 2
chr9_+_17841410 0.12 ENSRNOT00000031706
transmembrane protein 151B
chr1_+_199360645 0.12 ENSRNOT00000026527
lysine acetyltransferase 8
chr14_+_4125380 0.12 ENSRNOT00000002882
zinc finger protein 644
chr10_+_86711240 0.08 ENSRNOT00000012812
male specific lethal 1 homolog
chr6_+_127207732 0.01 ENSRNOT00000071976
similar to RIKEN cDNA A830059I20

Network of associatons between targets according to the STRING database.

First level regulatory network of Mzf1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 22.7 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
2.7 16.2 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
2.7 8.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
2.7 8.0 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
2.2 10.8 GO:0072697 protein localization to cell cortex(GO:0072697)
2.1 6.2 GO:2000054 regulation of mismatch repair(GO:0032423) regulation of chondrocyte development(GO:0061181) regulation of centromeric sister chromatid cohesion(GO:0070602) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
1.9 5.7 GO:0006344 maintenance of chromatin silencing(GO:0006344)
1.8 8.8 GO:0014043 negative regulation of neuron maturation(GO:0014043)
1.7 8.7 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
1.6 4.7 GO:0002481 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481)
1.4 8.4 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
1.2 3.6 GO:1990091 sodium-dependent self proteolysis(GO:1990091)
1.2 4.8 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
1.2 9.3 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
1.1 6.6 GO:0046208 spermine catabolic process(GO:0046208)
1.1 4.3 GO:2000814 positive regulation of barbed-end actin filament capping(GO:2000814)
1.1 3.2 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
1.1 6.4 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
1.1 12.7 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
1.1 3.2 GO:1904170 meiotic chromosome movement towards spindle pole(GO:0016344) regulation of bleb assembly(GO:1904170)
1.0 3.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
1.0 8.0 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.9 3.5 GO:0021571 rhombomere 5 development(GO:0021571)
0.8 3.1 GO:0034696 response to prostaglandin F(GO:0034696)
0.8 6.2 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.7 5.6 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.7 3.4 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.7 2.7 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.6 0.6 GO:0021569 rhombomere 3 development(GO:0021569) rhombomere 4 development(GO:0021570)
0.6 4.5 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.6 1.8 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.6 2.3 GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) notochord formation(GO:0014028)
0.6 4.0 GO:0040031 snRNA modification(GO:0040031)
0.5 1.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.5 1.5 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.5 2.4 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.4 3.4 GO:0001661 conditioned taste aversion(GO:0001661)
0.4 4.7 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.4 3.4 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.4 3.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.4 1.1 GO:0001966 thigmotaxis(GO:0001966)
0.4 3.3 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.4 1.1 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) vitamin D catabolic process(GO:0042369) response to sodium phosphate(GO:1904383)
0.4 1.9 GO:0001555 oocyte growth(GO:0001555)
0.4 11.8 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.4 2.2 GO:0010045 response to nickel cation(GO:0010045)
0.3 3.5 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.3 4.8 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.3 7.8 GO:0034377 plasma lipoprotein particle assembly(GO:0034377)
0.3 2.0 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.3 2.3 GO:0060751 branch elongation involved in mammary gland duct branching(GO:0060751)
0.3 2.0 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.3 2.5 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.3 2.1 GO:0060591 positive regulation of T-helper 2 cell differentiation(GO:0045630) chondroblast differentiation(GO:0060591)
0.3 4.4 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.3 0.8 GO:0044375 regulation of peroxisome size(GO:0044375)
0.2 5.4 GO:0071305 cellular response to vitamin D(GO:0071305)
0.2 4.0 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.2 0.9 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.2 0.7 GO:0014908 myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.2 1.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.2 1.5 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.2 2.5 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.2 1.9 GO:0090400 stress-induced premature senescence(GO:0090400)
0.2 3.9 GO:0016180 snRNA processing(GO:0016180)
0.2 2.1 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.2 1.5 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.1 0.8 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
0.1 2.1 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 1.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 2.9 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.1 1.7 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 1.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 1.8 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 1.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 10.2 GO:0006334 nucleosome assembly(GO:0006334)
0.1 2.0 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 1.4 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.1 1.8 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 0.7 GO:0009405 pathogenesis(GO:0009405)
0.1 1.9 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.1 3.0 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.1 2.2 GO:0014002 astrocyte development(GO:0014002)
0.1 0.9 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 2.3 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 1.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 5.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.5 GO:0006527 arginine catabolic process(GO:0006527)
0.0 1.3 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 3.1 GO:0006641 triglyceride metabolic process(GO:0006641)
0.0 0.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.9 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.7 GO:0048599 oocyte development(GO:0048599)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:0032398 MHC class Ib protein complex(GO:0032398)
1.0 5.9 GO:0035189 Rb-E2F complex(GO:0035189)
1.0 19.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.7 4.5 GO:0005642 annulate lamellae(GO:0005642)
0.7 4.3 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.7 3.4 GO:0035976 AP1 complex(GO:0035976)
0.7 2.0 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.7 2.0 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.6 4.7 GO:1990909 Wnt signalosome(GO:1990909)
0.6 5.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.6 2.8 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.5 4.8 GO:0001940 male pronucleus(GO:0001940)
0.5 5.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.5 5.7 GO:0071564 npBAF complex(GO:0071564)
0.5 4.8 GO:0042405 nuclear inclusion body(GO:0042405)
0.5 9.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.4 5.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.4 3.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.4 2.3 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.3 1.3 GO:0031417 NatC complex(GO:0031417)
0.3 4.3 GO:0016580 Sin3 complex(GO:0016580)
0.3 2.1 GO:0000243 commitment complex(GO:0000243)
0.2 2.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 3.9 GO:0032039 integrator complex(GO:0032039)
0.2 3.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 1.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.2 3.1 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.2 19.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 1.9 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 1.5 GO:0000974 Prp19 complex(GO:0000974)
0.1 1.9 GO:0032156 septin cytoskeleton(GO:0032156)
0.1 5.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 1.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 3.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 10.2 GO:0000786 nucleosome(GO:0000786)
0.1 1.7 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 9.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 8.1 GO:0005902 microvillus(GO:0005902)
0.1 7.9 GO:0032993 protein-DNA complex(GO:0032993)
0.1 4.0 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287)
0.1 0.8 GO:0071010 U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.1 0.3 GO:0001739 sex chromatin(GO:0001739)
0.1 18.0 GO:0005667 transcription factor complex(GO:0005667)
0.1 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 3.6 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 3.3 GO:0016605 PML body(GO:0016605)
0.0 16.9 GO:0016604 nuclear body(GO:0016604)
0.0 1.1 GO:0060077 inhibitory synapse(GO:0060077)
0.0 1.7 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 4.3 GO:0043209 myelin sheath(GO:0043209)
0.0 0.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 3.8 GO:0000790 nuclear chromatin(GO:0000790)
0.0 5.6 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.7 GO:0016363 nuclear matrix(GO:0016363)
0.0 11.6 GO:0005730 nucleolus(GO:0005730)
0.0 1.2 GO:0030175 filopodium(GO:0030175)
0.0 5.0 GO:0005813 centrosome(GO:0005813)
0.0 0.6 GO:0030286 dynein complex(GO:0030286)
0.0 0.9 GO:0042383 sarcolemma(GO:0042383)
0.0 0.9 GO:0005776 autophagosome(GO:0005776)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.6 GO:0046592 polyamine oxidase activity(GO:0046592)
1.6 8.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
1.2 4.8 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
1.0 3.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.7 2.2 GO:0017042 glycosylceramidase activity(GO:0017042)
0.7 4.3 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.6 1.9 GO:0032427 GBD domain binding(GO:0032427)
0.6 3.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.6 4.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.6 4.4 GO:0034452 dynactin binding(GO:0034452)
0.5 10.8 GO:0032794 GTPase activating protein binding(GO:0032794)
0.5 2.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.5 10.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.5 8.0 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.4 4.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.4 6.2 GO:0070411 I-SMAD binding(GO:0070411)
0.4 5.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.4 2.4 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.4 11.4 GO:0050699 WW domain binding(GO:0050699)
0.3 6.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.3 8.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.3 1.9 GO:0048185 activin binding(GO:0048185)
0.3 3.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.3 2.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.3 0.9 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.3 16.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.3 2.1 GO:0035197 siRNA binding(GO:0035197)
0.3 3.6 GO:0031432 titin binding(GO:0031432)
0.3 1.5 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.3 4.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 10.3 GO:0042605 peptide antigen binding(GO:0042605)
0.2 2.1 GO:1990446 U1 snRNA binding(GO:0030619) U1 snRNP binding(GO:1990446)
0.2 9.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 5.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 1.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.2 3.1 GO:0000400 four-way junction DNA binding(GO:0000400)
0.2 1.5 GO:0001055 RNA polymerase II activity(GO:0001055)
0.2 2.9 GO:0043422 protein kinase B binding(GO:0043422)
0.2 0.9 GO:0003680 AT DNA binding(GO:0003680)
0.2 1.9 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.2 1.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 0.5 GO:0016403 dimethylargininase activity(GO:0016403)
0.2 11.4 GO:0030295 protein kinase activator activity(GO:0030295)
0.1 30.1 GO:0001047 core promoter binding(GO:0001047)
0.1 0.8 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 1.4 GO:0035198 miRNA binding(GO:0035198)
0.1 2.0 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 7.2 GO:0035064 methylated histone binding(GO:0035064)
0.1 3.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 3.2 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.1 1.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 4.8 GO:0070063 RNA polymerase binding(GO:0070063)
0.1 1.5 GO:0008143 poly(A) binding(GO:0008143)
0.1 5.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 1.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 2.5 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 4.0 GO:0005109 frizzled binding(GO:0005109)
0.1 1.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 4.0 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.1 0.7 GO:0008432 JUN kinase binding(GO:0008432)
0.1 1.8 GO:0030371 translation repressor activity(GO:0030371)
0.1 1.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 2.2 GO:0042054 histone methyltransferase activity(GO:0042054)
0.1 12.1 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 5.0 GO:0003777 microtubule motor activity(GO:0003777)
0.1 3.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 0.4 GO:0017091 AU-rich element binding(GO:0017091)
0.1 2.3 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 1.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.2 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 4.0 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 1.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 3.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 6.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 2.7 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 2.4 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 2.8 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 1.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 16.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.6 13.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.4 8.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.4 18.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.3 4.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.3 3.4 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 11.6 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.2 5.6 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 8.2 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 6.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 2.4 ST GA12 PATHWAY G alpha 12 Pathway
0.1 1.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 7.4 PID CDC42 PATHWAY CDC42 signaling events
0.1 2.1 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 4.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 4.1 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 2.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 1.9 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.1 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 18.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.4 8.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.4 14.8 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.4 6.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.4 2.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.4 5.6 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.3 7.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.3 3.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.3 4.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 3.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 4.8 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 5.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 5.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 3.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 2.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 3.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.5 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 1.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.1 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 2.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 0.8 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 2.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 2.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 1.5 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 1.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.6 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 3.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 2.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 2.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 2.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling