ISMARA results: Myog

Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation

Downloads

Results for Myog_Tcf12

Z-value: 2.20

Motif logo

Transcription factors associated with Myog_Tcf12

Gene Symbol	Gene ID	Gene Info
Myog NCBI RGD Ensembl	ENSRNOG00000030743	myogenin
Tcf12 NCBI RGD Ensembl	ENSRNOG00000057754	transcription factor 12

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Myog	rn6_v1_chr13_+_51126459_51126459	0.27	1.5e-06	Click!
Tcf12	rn6_v1_chr8_-_78655856_78655856	-0.12	2.8e-02	Click!

Activity profile of Myog_Tcf12 motif

Sorted Z-values of Myog_Tcf12 motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr3_-_168018410 Show fit	165.44	ENSRNOT00000087579	Bcas1 NCBI RGD Ensembl Show fit	breast carcinoma amplified sequence 1
chr19_-_11326139 Show fit	112.40	ENSRNOT00000025669	Mt3 NCBI RGD Ensembl Show fit	metallothionein 3
chr10_-_8654892 Show fit	104.78	ENSRNOT00000066534	Rbfox1 NCBI RGD Ensembl Show fit	RNA binding protein, fox-1 homolog 1
chr2_-_231521052 Show fit	102.96	ENSRNOT00000089534 ENSRNOT00000080470 ENSRNOT00000084756	Ank2 NCBI RGD Ensembl Show fit	ankyrin 2
chr9_+_14529218 Show fit	88.86	ENSRNOT00000016893	Apobec2 NCBI RGD Ensembl Show fit	apolipoprotein B mRNA editing enzyme catalytic subunit 2
chr1_-_81881549 Show fit	72.91	ENSRNOT00000027497	Atp1a3 NCBI RGD Ensembl Show fit	ATPase Na+/K+ transporting subunit alpha 3
chr10_-_15928169 Show fit	69.43	ENSRNOT00000028069	Nsg2 NCBI RGD Ensembl Show fit	neuron specific gene family member 2
chr10_+_92628356 Show fit	69.15	ENSRNOT00000072480	Myl4 NCBI RGD Ensembl Show fit	myosin, light chain 4
chr10_-_87578854 Show fit	65.81	ENSRNOT00000065619	LOC680160 NCBI RGD Ensembl Show fit	similar to keratin associated protein 4-7
chr17_+_81922329 Show fit	65.15	ENSRNOT00000031542	Cacnb2 NCBI RGD Ensembl Show fit	calcium voltage-gated channel auxiliary subunit beta 2

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Myog_Tcf12

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
8.6	179.7	GO:2001014	regulation of skeletal muscle cell differentiation(GO:2001014)
36.6	146.3	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
1.9	119.3	GO:1901379	regulation of potassium ion transmembrane transport(GO:1901379)
14.7	117.9	GO:0051694	pointed-end actin filament capping(GO:0051694)
37.5	112.4	GO:0055073	cadmium ion homeostasis(GO:0055073) regulation of lysosomal membrane permeability(GO:0097213) positive regulation of lysosomal membrane permeability(GO:0097214) regulation of hydrogen peroxide catabolic process(GO:2000295)
2.8	109.2	GO:0003009	skeletal muscle contraction(GO:0003009)
25.7	103.0	GO:0036309	protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
10.8	86.6	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
3.0	81.7	GO:0002026	regulation of the force of heart contraction(GO:0002026)
13.4	80.1	GO:1990573	potassium ion import across plasma membrane(GO:1990573)

Showing 1 to 10 of 322 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
5.8	298.1	GO:0031672	A band(GO:0031672)
2.4	244.8	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
1.9	239.4	GO:0030017	sarcomere(GO:0030017)
0.8	231.0	GO:0099572	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
1.0	193.2	GO:0005802	trans-Golgi network(GO:0005802)
11.4	136.8	GO:0005861	troponin complex(GO:0005861)
6.1	122.0	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
14.1	112.4	GO:0097450	astrocyte end-foot(GO:0097450)
3.5	101.6	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.5	89.7	GO:0043209	myelin sheath(GO:0043209)

Showing 1 to 10 of 152 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
4.7	285.3	GO:0015459	potassium channel regulator activity(GO:0015459)
0.9	174.1	GO:0003729	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
4.3	163.9	GO:0008307	structural constituent of muscle(GO:0008307)
8.3	115.8	GO:0005523	tropomyosin binding(GO:0005523)
10.2	112.4	GO:0046870	cadmium ion binding(GO:0046870)
4.1	101.4	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
2.1	100.5	GO:0019213	deacetylase activity(GO:0019213)
3.2	99.0	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.3	94.3	GO:0015631	tubulin binding(GO:0015631)
12.4	86.6	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)

Showing 1 to 10 of 196 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
5.7	147.3	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.4	132.6	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.5	89.9	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
1.9	66.8	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
1.1	63.9	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
1.6	54.7	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
2.0	45.3	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
1.9	39.4	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.6	39.3	PID NOTCH PATHWAY	Notch signaling pathway
0.8	37.9	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling

Showing 1 to 10 of 48 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
8.3	314.1	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
9.2	165.3	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
4.1	143.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
1.3	102.5	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
2.6	97.1	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
3.2	78.8	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
3.0	76.9	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
1.3	64.5	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.8	58.9	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
3.6	54.4	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline

Showing 1 to 10 of 81 entries

Results for Myog_Tcf12

Z-value: 2.20

Motif logo

Transcription factors associated with Myog_Tcf12

Activity-expression correlation:

Activity profile of Myog_Tcf12 motif

Sorted Z-values of Myog_Tcf12 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Myog_Tcf12

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: