ISMARA results: Myog

Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Myog_Tcf12

Z-value: 2.20

Motif logo

Transcription factors associated with Myog_Tcf12

Gene Symbol	Gene ID	Gene Info
Myog NCBI RGD Ensembl	ENSRNOG00000030743	myogenin
Tcf12 NCBI RGD Ensembl	ENSRNOG00000057754	transcription factor 12

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Myog	rn6_v1_chr13_+_51126459_51126459	0.27	1.5e-06	Click!
Tcf12	rn6_v1_chr8_-_78655856_78655856	-0.12	2.8e-02	Click!

Activity profile of Myog_Tcf12 motif

Sorted Z-values of Myog_Tcf12 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr3_-_168018410 Show fit	165.44	ENSRNOT00000087579	Bcas1 NCBI RGD Ensembl Show fit	breast carcinoma amplified sequence 1
chr19_-_11326139 Show fit	112.40	ENSRNOT00000025669	Mt3 NCBI RGD Ensembl Show fit	metallothionein 3
chr10_-_8654892 Show fit	104.78	ENSRNOT00000066534	Rbfox1 NCBI RGD Ensembl Show fit	RNA binding protein, fox-1 homolog 1
chr2_-_231521052 Show fit	102.96	ENSRNOT00000089534 ENSRNOT00000080470 ENSRNOT00000084756	Ank2 NCBI RGD Ensembl Show fit	ankyrin 2
chr9_+_14529218 Show fit	88.86	ENSRNOT00000016893	Apobec2 NCBI RGD Ensembl Show fit	apolipoprotein B mRNA editing enzyme catalytic subunit 2
chr1_-_81881549 Show fit	72.91	ENSRNOT00000027497	Atp1a3 NCBI RGD Ensembl Show fit	ATPase Na+/K+ transporting subunit alpha 3
chr10_-_15928169 Show fit	69.43	ENSRNOT00000028069	Nsg2 NCBI RGD Ensembl Show fit	neuron specific gene family member 2
chr10_+_92628356 Show fit	69.15	ENSRNOT00000072480	Myl4 NCBI RGD Ensembl Show fit	myosin, light chain 4
chr10_-_87578854 Show fit	65.81	ENSRNOT00000065619	LOC680160 NCBI RGD Ensembl Show fit	similar to keratin associated protein 4-7
chr17_+_81922329 Show fit	65.15	ENSRNOT00000031542	Cacnb2 NCBI RGD Ensembl Show fit	calcium voltage-gated channel auxiliary subunit beta 2
chr18_+_52215682 Show fit	61.30	ENSRNOT00000037901	Megf10 NCBI RGD Ensembl Show fit	multiple EGF-like domains 10
chr18_+_56193978 Show fit	61.18	ENSRNOT00000041533 ENSRNOT00000080177	Camk2a NCBI RGD Ensembl Show fit	calcium/calmodulin-dependent protein kinase II alpha
chr10_-_8498422 Show fit	60.98	ENSRNOT00000082332	Rbfox1 NCBI RGD Ensembl Show fit	RNA binding protein, fox-1 homolog 1
chr3_+_11114551 Show fit	59.73	ENSRNOT00000013507	Plpp7 NCBI RGD Ensembl Show fit	phospholipid phosphatase 7
chr14_-_86297623 Show fit	59.58	ENSRNOT00000067162 ENSRNOT00000081607 ENSRNOT00000085265	Camk2b NCBI RGD Ensembl Show fit	calcium/calmodulin-dependent protein kinase II beta
chrX_+_105239840 Show fit	59.47	ENSRNOT00000039864	Drp2 NCBI RGD Ensembl Show fit	dystrophin related protein 2
chr2_-_21698937 Show fit	58.29	ENSRNOT00000080165	AABR07007642.1 NCBI RGD Ensembl Show fit
chr11_+_72705129 Show fit	56.43	ENSRNOT00000073330	Apod NCBI RGD Ensembl Show fit	apolipoprotein D
chr1_-_73753128 Show fit	56.23	ENSRNOT00000068459	Ttyh1 NCBI RGD Ensembl Show fit	tweety family member 1
chr4_-_147163467 Show fit	56.20	ENSRNOT00000010748	Timp4 NCBI RGD Ensembl Show fit	tissue inhibitor of metalloproteinase 4
chr1_-_102106127 Show fit	55.86	ENSRNOT00000028685	Kcnj11 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily J member 11
chrX_+_23081125 Show fit	53.49	ENSRNOT00000071639	AABR07037520.1 NCBI RGD Ensembl Show fit
chr9_-_82699551 Show fit	51.99	ENSRNOT00000020673	Obsl1 NCBI RGD Ensembl Show fit	obscurin-like 1
chr16_+_81616604 Show fit	51.54	ENSRNOT00000026392 ENSRNOT00000057740	Adprhl1 NCBI RGD Ensembl Show fit Grtp1 NCBI RGD Ensembl Show fit	ADP-ribosylhydrolase like 1 growth hormone regulated TBC protein 1
chr2_+_11658568 Show fit	49.13	ENSRNOT00000076408 ENSRNOT00000076416 ENSRNOT00000076992 ENSRNOT00000075931 ENSRNOT00000076136 ENSRNOT00000076481 ENSRNOT00000076084 ENSRNOT00000076230 ENSRNOT00000076710 ENSRNOT00000076239	Mef2c NCBI RGD Ensembl Show fit	myocyte enhancer factor 2C
chr1_-_80331626 Show fit	48.65	ENSRNOT00000022577	AABR07002677.1 NCBI RGD Ensembl Show fit
chr2_+_210977938 Show fit	48.26	ENSRNOT00000074725	Amigo1 NCBI RGD Ensembl Show fit	adhesion molecule with Ig like domain 1
chr7_-_50278842 Show fit	47.59	ENSRNOT00000088950	Syt1 NCBI RGD Ensembl Show fit	synaptotagmin 1
chr1_+_222310920 Show fit	47.54	ENSRNOT00000091465	Macrod1 NCBI RGD Ensembl Show fit	MACRO domain containing 1
chr1_+_222311253 Show fit	47.26	ENSRNOT00000028749	Macrod1 NCBI RGD Ensembl Show fit	MACRO domain containing 1
chr5_-_109651730 Show fit	47.00	ENSRNOT00000093032	Elavl2 NCBI RGD Ensembl Show fit	ELAV like RNA binding protein 2
chr1_+_79989019 Show fit	46.53	ENSRNOT00000020428	Dmpk NCBI RGD Ensembl Show fit	dystrophia myotonica-protein kinase
chr14_+_60764409 Show fit	46.35	ENSRNOT00000005168	Lgi2 NCBI RGD Ensembl Show fit	leucine-rich repeat LGI family, member 2
chr17_+_1679627 Show fit	45.85	ENSRNOT00000025801	Habp4 NCBI RGD Ensembl Show fit	hyaluronan binding protein 4
chr10_+_70262361 Show fit	45.79	ENSRNOT00000064625 ENSRNOT00000076973	Unc45b NCBI RGD Ensembl Show fit	unc-45 myosin chaperone B
chr3_+_41019898 Show fit	45.29	ENSRNOT00000007335	Kcnj3 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily J member 3
chr5_+_144634143 Show fit	44.71	ENSRNOT00000075558	RGD1563072 NCBI RGD Ensembl Show fit	similar to hypothetical protein FLJ38984
chr10_-_95934345 Show fit	44.33	ENSRNOT00000004349	Cacng1 NCBI RGD Ensembl Show fit	calcium voltage-gated channel auxiliary subunit gamma 1
chr4_+_51553454 Show fit	43.14	ENSRNOT00000073466	LOC100909784 NCBI RGD Ensembl Show fit	leiomodin-2-like
chr10_-_94557764 Show fit	42.16	ENSRNOT00000016841	Scn4a NCBI RGD Ensembl Show fit	sodium voltage-gated channel alpha subunit 4
chr2_+_242882306 Show fit	41.68	ENSRNOT00000013661	Ddit4l NCBI RGD Ensembl Show fit	DNA-damage-inducible transcript 4-like
chr1_-_89560719 Show fit	41.65	ENSRNOT00000028653	Scn1b NCBI RGD Ensembl Show fit	sodium voltage-gated channel beta subunit 1
chr13_+_52662996 Show fit	40.92	ENSRNOT00000047682	Tnnt2 NCBI RGD Ensembl Show fit	troponin T2, cardiac type
chr15_+_110114148 Show fit	40.89	ENSRNOT00000006264	Itgbl1 NCBI RGD Ensembl Show fit	integrin subunit beta like 1
chr3_-_161246351 Show fit	40.67	ENSRNOT00000020348	Tnnc2 NCBI RGD Ensembl Show fit	troponin C2, fast skeletal type
chr1_+_78800754 Show fit	40.55	ENSRNOT00000084601	Dact3 NCBI RGD Ensembl Show fit	dishevelled-binding antagonist of beta-catenin 3
chr4_+_51661654 Show fit	40.52	ENSRNOT00000087359 ENSRNOT00000072470	LOC100909784 NCBI RGD Ensembl Show fit	leiomodin-2-like
chr1_+_80321585 Show fit	39.90	ENSRNOT00000022895	Ckm NCBI RGD Ensembl Show fit	creatine kinase, M-type
chr4_-_157381105 Show fit	39.82	ENSRNOT00000021670	Gpr162 NCBI RGD Ensembl Show fit	G protein-coupled receptor 162
chr12_+_24473981 Show fit	39.53	ENSRNOT00000001973	Fzd9 NCBI RGD Ensembl Show fit	frizzled class receptor 9
chr6_-_147172813 Show fit	39.38	ENSRNOT00000066545	Itgb8 NCBI RGD Ensembl Show fit	integrin subunit beta 8
chr9_+_82700468 Show fit	39.03	ENSRNOT00000027227	Inha NCBI RGD Ensembl Show fit	inhibin alpha subunit
chr9_-_55673704 Show fit	38.63	ENSRNOT00000066231 ENSRNOT00000081677	Tmeff2 NCBI RGD Ensembl Show fit	transmembrane protein with EGF-like and two follistatin-like domains 2
chr13_+_85818427 Show fit	38.48	ENSRNOT00000077227 ENSRNOT00000006117	Rxrg NCBI RGD Ensembl Show fit	retinoid X receptor gamma
chr19_-_43596801 Show fit	38.32	ENSRNOT00000025625	Fa2h NCBI RGD Ensembl Show fit	fatty acid 2-hydroxylase
chr9_-_93735636 Show fit	38.28	ENSRNOT00000025582	Nppc NCBI RGD Ensembl Show fit	natriuretic peptide C
chr17_+_13670520 Show fit	38.25	ENSRNOT00000019442	Shc3 NCBI RGD Ensembl Show fit	SHC adaptor protein 3
chr1_-_89560469 Show fit	38.19	ENSRNOT00000079091	Scn1b NCBI RGD Ensembl Show fit	sodium voltage-gated channel beta subunit 1
chr5_+_1417478 Show fit	38.07	ENSRNOT00000008153 ENSRNOT00000085564	Jph1 NCBI RGD Ensembl Show fit	junctophilin 1
chrX_+_86126157 Show fit	37.90	ENSRNOT00000006992	Klhl4 NCBI RGD Ensembl Show fit	kelch-like family member 4
chr3_+_35014538 Show fit	37.77	ENSRNOT00000006341	Kif5c NCBI RGD Ensembl Show fit	kinesin family member 5C
chr7_-_115910522 Show fit	37.23	ENSRNOT00000076998 ENSRNOT00000067442	Arc NCBI RGD Ensembl Show fit	activity-regulated cytoskeleton-associated protein
chr5_-_160179978 Show fit	37.12	ENSRNOT00000022820	Slc25a34 NCBI RGD Ensembl Show fit	solute carrier family 25, member 34
chr10_-_62699723 Show fit	37.06	ENSRNOT00000086706	Coro6 NCBI RGD Ensembl Show fit	coronin 6
chr1_-_215846911 Show fit	36.67	ENSRNOT00000089171	Igf2 NCBI RGD Ensembl Show fit	insulin-like growth factor 2
chr1_+_142883040 Show fit	36.58	ENSRNOT00000015898	Alpk3 NCBI RGD Ensembl Show fit	alpha-kinase 3
chr6_+_76349362 Show fit	36.52	ENSRNOT00000043224	Aldoart2 NCBI RGD Ensembl Show fit	aldolase 1 A retrogene 2
chr9_+_82556573 Show fit	36.44	ENSRNOT00000026860	Des NCBI RGD Ensembl Show fit	desmin
chr8_-_23063041 Show fit	36.36	ENSRNOT00000018416	Elavl3 NCBI RGD Ensembl Show fit	ELAV like RNA binding protein 3
chr1_+_215609645 Show fit	36.31	ENSRNOT00000076140 ENSRNOT00000027487	Tnni2 NCBI RGD Ensembl Show fit	troponin I2, fast skeletal type
chr1_-_78851719 Show fit	35.89	ENSRNOT00000022603	Calm2 NCBI RGD Ensembl Show fit	calmodulin 2
chr2_-_257484587 Show fit	35.84	ENSRNOT00000083344	Nexn NCBI RGD Ensembl Show fit	nexilin (F actin binding protein)
chr7_-_2786856 Show fit	35.77	ENSRNOT00000047530 ENSRNOT00000086939	Coq10a NCBI RGD Ensembl Show fit	coenzyme Q10A
chr18_-_37245809 Show fit	35.67	ENSRNOT00000079585	Ppp2r2b NCBI RGD Ensembl Show fit	protein phosphatase 2, regulatory subunit B, beta
chr1_-_31055453 Show fit	34.94	ENSRNOT00000031083	Soga3 NCBI RGD Ensembl Show fit	SOGA family member 3
chr20_-_4823475 Show fit	34.92	ENSRNOT00000082536 ENSRNOT00000001114	Atp6v1g2 NCBI RGD Ensembl Show fit	ATPase H+ transporting V1 subunit G2
chr8_+_63600663 Show fit	34.81	ENSRNOT00000012644	Hcn4 NCBI RGD Ensembl Show fit	hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr9_+_82120059 Show fit	34.77	ENSRNOT00000057368	Cdk5r2 NCBI RGD Ensembl Show fit	cyclin-dependent kinase 5 regulatory subunit 2
chr4_+_113968995 Show fit	34.59	ENSRNOT00000079511	Rtkn NCBI RGD Ensembl Show fit	rhotekin
chr8_-_84632817 Show fit	34.54	ENSRNOT00000076942	Mlip NCBI RGD Ensembl Show fit	muscular LMNA-interacting protein
chr17_-_80320681 Show fit	34.39	ENSRNOT00000023637	C1ql3 NCBI RGD Ensembl Show fit	complement C1q like 3
chr8_-_21831668 Show fit	34.34	ENSRNOT00000027897	Col5a3 NCBI RGD Ensembl Show fit	collagen type V alpha 3 chain
chr3_-_102151489 Show fit	34.33	ENSRNOT00000006349	Ano3 NCBI RGD Ensembl Show fit	anoctamin 3
chr4_-_129619142 Show fit	34.25	ENSRNOT00000047453	Lmod3 NCBI RGD Ensembl Show fit	leiomodin 3
chr13_-_42263024 Show fit	34.03	ENSRNOT00000004741	Lypd1 NCBI RGD Ensembl Show fit	Ly6/Plaur domain containing 1
chr1_+_220416018 Show fit	33.68	ENSRNOT00000027233	B4gat1 NCBI RGD Ensembl Show fit	beta-1,4-glucuronyltransferase 1
chr3_-_105279462 Show fit	33.63	ENSRNOT00000010679	Scg5 NCBI RGD Ensembl Show fit	secretogranin V
chr5_-_59025631 Show fit	33.38	ENSRNOT00000049000 ENSRNOT00000022801	Tpm2 NCBI RGD Ensembl Show fit	tropomyosin 2, beta
chrX_+_110404022 Show fit	33.28	ENSRNOT00000041044	Mum1l1 NCBI RGD Ensembl Show fit	MUM1 like 1
chr12_-_6740714 Show fit	33.26	ENSRNOT00000001205	Medag NCBI RGD Ensembl Show fit	mesenteric estrogen-dependent adipogenesis
chr15_+_23792931 Show fit	33.02	ENSRNOT00000092091	Samd4a NCBI RGD Ensembl Show fit	sterile alpha motif domain containing 4A
chrX_-_136807885 Show fit	32.74	ENSRNOT00000010325	Igsf1 NCBI RGD Ensembl Show fit	immunoglobulin superfamily, member 1
chr15_+_19547871 Show fit	32.35	ENSRNOT00000036235	Gpr137c NCBI RGD Ensembl Show fit	G protein-coupled receptor 137C
chr2_-_188138177 Show fit	32.03	ENSRNOT00000027474	Syt11 NCBI RGD Ensembl Show fit	synaptotagmin 11
chr20_+_5008508 Show fit	31.82	ENSRNOT00000001153	Vwa7 NCBI RGD Ensembl Show fit	von Willebrand factor A domain containing 7
chr3_-_2689084 Show fit	30.97	ENSRNOT00000020926	Ptgds NCBI RGD Ensembl Show fit	prostaglandin D2 synthase
chr5_+_154112076 Show fit	30.79	ENSRNOT00000044969	Myom3 NCBI RGD Ensembl Show fit	myomesin 3
chr9_+_9961021 Show fit	30.68	ENSRNOT00000075767	Tubb4a NCBI RGD Ensembl Show fit	tubulin, beta 4A class IVa
chr1_-_265573117 Show fit	30.64	ENSRNOT00000044195 ENSRNOT00000055915	LOC100911951 NCBI RGD Ensembl Show fit	Kv channel-interacting protein 2-like
chr13_-_82005741 Show fit	30.41	ENSRNOT00000076404	Mettl11b NCBI RGD Ensembl Show fit	methyltransferase like 11B
chr2_-_172361779 Show fit	30.31	ENSRNOT00000085876	Schip1 NCBI RGD Ensembl Show fit	schwannomin interacting protein 1
chr18_+_16650806 Show fit	30.10	ENSRNOT00000093679 ENSRNOT00000041961 ENSRNOT00000093140	Fhod3 NCBI RGD Ensembl Show fit	formin homology 2 domain containing 3
chr20_+_3556975 Show fit	29.91	ENSRNOT00000089417	Ddr1 NCBI RGD Ensembl Show fit	discoidin domain receptor tyrosine kinase 1
chr4_+_7076759 Show fit	29.68	ENSRNOT00000066598	Smarcd3 NCBI RGD Ensembl Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr11_+_27208564 Show fit	29.50	ENSRNOT00000002158	Map3k7cl NCBI RGD Ensembl Show fit	MAP3K7 C-terminal like
chr7_-_12274803 Show fit	29.44	ENSRNOT00000049146	Apc2 NCBI RGD Ensembl Show fit	APC2, WNT signaling pathway regulator
chr3_-_147143576 Show fit	29.16	ENSRNOT00000091811 ENSRNOT00000012727	Snph NCBI RGD Ensembl Show fit	syntaphilin
chr13_-_82006005 Show fit	29.10	ENSRNOT00000039581	Mettl11b NCBI RGD Ensembl Show fit	methyltransferase like 11B
chr14_-_112946875 Show fit	28.76	ENSRNOT00000081981	LOC103690141 NCBI RGD Ensembl Show fit	coiled-coil domain-containing protein 85A-like
chr4_+_9966891 Show fit	28.65	ENSRNOT00000086609	Napepld NCBI RGD Ensembl Show fit	N-acyl phosphatidylethanolamine phospholipase D
chr4_-_117268178 Show fit	28.53	ENSRNOT00000043201 ENSRNOT00000084049	Fbxo41 NCBI RGD Ensembl Show fit	F-box protein 41
chr12_-_36398206 Show fit	28.48	ENSRNOT00000090944 ENSRNOT00000058492	Tmem132b NCBI RGD Ensembl Show fit	transmembrane protein 132B
chr2_-_115836846 Show fit	28.26	ENSRNOT00000014359	Cldn11 NCBI RGD Ensembl Show fit	claudin 11
chr1_+_167197549 Show fit	27.95	ENSRNOT00000027427	Art1 NCBI RGD Ensembl Show fit	ADP-ribosyltransferase 1
chr1_-_31122093 Show fit	27.65	ENSRNOT00000016712	NEWGENE_1307525 NCBI RGD Ensembl Show fit	SOGA family member 3
chr1_+_101884276 Show fit	27.62	ENSRNOT00000082917	Tmem143 NCBI RGD Ensembl Show fit	transmembrane protein 143
chr15_-_90175802 Show fit	27.54	ENSRNOT00000013342	Spry2 NCBI RGD Ensembl Show fit	sprouty RTK signaling antagonist 2
chr4_+_84597323 Show fit	27.29	ENSRNOT00000074054 ENSRNOT00000012755	Wipf3 NCBI RGD Ensembl Show fit	WAS/WASL interacting protein family, member 3
chr13_-_39643361 Show fit	26.89	ENSRNOT00000003527	Dpp10 NCBI RGD Ensembl Show fit	dipeptidylpeptidase 10
chr16_+_34795971 Show fit	26.84	ENSRNOT00000043510	LOC100912321 NCBI RGD Ensembl Show fit	myeloid-associated differentiation marker-like
chr8_+_27777179 Show fit	26.75	ENSRNOT00000009825	B3gat1 NCBI RGD Ensembl Show fit	beta-1,3-glucuronyltransferase 1
chr14_+_66598259 Show fit	26.56	ENSRNOT00000049743	Kcnip4 NCBI RGD Ensembl Show fit	potassium voltage-gated channel interacting protein 4
chr4_+_136512201 Show fit	26.51	ENSRNOT00000051645	Cntn6 NCBI RGD Ensembl Show fit	contactin 6
chr4_+_113970079 Show fit	26.47	ENSRNOT00000079547	Rtkn NCBI RGD Ensembl Show fit	rhotekin
chr1_-_140262452 Show fit	26.47	ENSRNOT00000046849 ENSRNOT00000045165 ENSRNOT00000025536 ENSRNOT00000041839	Ntrk3 NCBI RGD Ensembl Show fit	neurotrophic receptor tyrosine kinase 3
chr20_+_40236437 Show fit	26.15	ENSRNOT00000000743	Hs3st5 NCBI RGD Ensembl Show fit	heparan sulfate-glucosamine 3-sulfotransferase 5
chr2_+_155718359 Show fit	26.03	ENSRNOT00000077973	Kcnab1 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily A member regulatory beta subunit 1
chr10_+_11393103 Show fit	25.85	ENSRNOT00000076022	Adcy9 NCBI RGD Ensembl Show fit	adenylate cyclase 9
chr1_+_220322940 Show fit	25.80	ENSRNOT00000074972	LOC108348085 NCBI RGD Ensembl Show fit	beta-1,4-glucuronyltransferase 1
chr14_+_12218553 Show fit	25.75	ENSRNOT00000003237	Prkg2 NCBI RGD Ensembl Show fit	protein kinase, cGMP-dependent, type II
chr15_+_34251606 Show fit	25.64	ENSRNOT00000025725	Fitm1 NCBI RGD Ensembl Show fit	fat storage-inducing transmembrane protein 1
chr3_-_66885085 Show fit	25.50	ENSRNOT00000084299 ENSRNOT00000090547	Pde1a NCBI RGD Ensembl Show fit	phosphodiesterase 1A
chr19_-_58735173 Show fit	25.47	ENSRNOT00000030077	Pcnx2 NCBI RGD Ensembl Show fit	pecanex homolog 2 (Drosophila)
chr10_-_45534570 Show fit	25.34	ENSRNOT00000058362	Gjc2 NCBI RGD Ensembl Show fit	gap junction protein, gamma 2
chr2_+_54191538 Show fit	25.32	ENSRNOT00000019524	Plcxd3 NCBI RGD Ensembl Show fit	phosphatidylinositol-specific phospholipase C, X domain containing 3
chr5_+_145257714 Show fit	25.29	ENSRNOT00000019214	Dlgap3 NCBI RGD Ensembl Show fit	DLG associated protein 3
chr11_-_87449940 Show fit	25.19	ENSRNOT00000002560	Slc7a4 NCBI RGD Ensembl Show fit	solute carrier family 7, member 4
chr8_+_119030875 Show fit	25.06	ENSRNOT00000028458	Myl3 NCBI RGD Ensembl Show fit	myosin light chain 3
chr20_+_2004052 Show fit	24.95	ENSRNOT00000001008	Mog NCBI RGD Ensembl Show fit	myelin oligodendrocyte glycoprotein
chr4_+_71675383 Show fit	24.92	ENSRNOT00000051265	Clcn1 NCBI RGD Ensembl Show fit	chloride voltage-gated channel 1
chr13_-_76049363 Show fit	24.33	ENSRNOT00000075865 ENSRNOT00000007455	Brinp2 NCBI RGD Ensembl Show fit	BMP/retinoic acid inducible neural specific 2
chr5_-_40237591 Show fit	24.20	ENSRNOT00000011393	Fut9 NCBI RGD Ensembl Show fit	fucosyltransferase 9
chr3_+_80075991 Show fit	23.87	ENSRNOT00000080266	Pacsin3 NCBI RGD Ensembl Show fit	protein kinase C and casein kinase substrate in neurons 3
chr15_+_33600102 Show fit	23.80	ENSRNOT00000022664	Cmtm5 NCBI RGD Ensembl Show fit	CKLF-like MARVEL transmembrane domain containing 5
chrX_+_69730242 Show fit	23.44	ENSRNOT00000075980 ENSRNOT00000076425	Eda NCBI RGD Ensembl Show fit	ectodysplasin-A
chr15_+_4240203 Show fit	23.39	ENSRNOT00000010178	Mss51 NCBI RGD Ensembl Show fit	MSS51 mitochondrial translational activator
chr12_+_49761120 Show fit	23.18	ENSRNOT00000070961	Myo18b NCBI RGD Ensembl Show fit	myosin XVIIIb
chr10_+_90930010 Show fit	23.15	ENSRNOT00000003765	Higd1b NCBI RGD Ensembl Show fit	HIG1 hypoxia inducible domain family, member 1B
chrX_+_92131209 Show fit	23.04	ENSRNOT00000004462	Pabpc5 NCBI RGD Ensembl Show fit	poly A binding protein, cytoplasmic 5
chr7_-_121029754 Show fit	23.00	ENSRNOT00000004703	Nptxr NCBI RGD Ensembl Show fit	neuronal pentraxin receptor
chr1_+_262892545 Show fit	22.81	ENSRNOT00000068278 ENSRNOT00000024709 ENSRNOT00000024750	Kcnip2 NCBI RGD Ensembl Show fit	potassium voltage-gated channel interacting protein 2
chr3_+_56861396 Show fit	22.75	ENSRNOT00000000008 ENSRNOT00000084375	Gad1 NCBI RGD Ensembl Show fit	glutamate decarboxylase 1
chr15_+_33600337 Show fit	22.68	ENSRNOT00000075965	Cmtm5 NCBI RGD Ensembl Show fit	CKLF-like MARVEL transmembrane domain containing 5
chr12_-_5773036 Show fit	22.53	ENSRNOT00000041365	Fry NCBI RGD Ensembl Show fit	FRY microtubule binding protein
chr4_+_41364441 Show fit	22.52	ENSRNOT00000087146	Foxp2 NCBI RGD Ensembl Show fit	forkhead box P2
chr1_-_215423099 Show fit	22.42	ENSRNOT00000027259	AABR07006049.1 NCBI RGD Ensembl Show fit
chr13_+_60435946 Show fit	22.35	ENSRNOT00000004342	B3galt2 NCBI RGD Ensembl Show fit	Beta-1,3-galactosyltransferase 2
chr4_+_180291389 Show fit	22.34	ENSRNOT00000002465	Sspn NCBI RGD Ensembl Show fit	sarcospan
chr14_-_112946204 Show fit	22.12	ENSRNOT00000056813	LOC103690141 NCBI RGD Ensembl Show fit	coiled-coil domain-containing protein 85A-like
chr9_-_80166807 Show fit	22.10	ENSRNOT00000079493	Igfbp5 NCBI RGD Ensembl Show fit	insulin-like growth factor binding protein 5
chr14_-_84106997 Show fit	22.02	ENSRNOT00000065501	Osbp2 NCBI RGD Ensembl Show fit	oxysterol binding protein 2
chr18_-_38088457 Show fit	22.01	ENSRNOT00000077814	Jakmip2 NCBI RGD Ensembl Show fit	janus kinase and microtubule interacting protein 2
chrX_+_71342775 Show fit	21.89	ENSRNOT00000004888	Itgb1bp2 NCBI RGD Ensembl Show fit	integrin subunit beta 1 binding protein 2
chr10_-_110101872 Show fit	21.85	ENSRNOT00000071893	Ccdc57 NCBI RGD Ensembl Show fit	coiled-coil domain containing 57
chr8_+_116715755 Show fit	21.64	ENSRNOT00000090239	Camkv NCBI RGD Ensembl Show fit	CaM kinase-like vesicle-associated
chr7_+_120153184 Show fit	21.58	ENSRNOT00000013538	Lgals1 NCBI RGD Ensembl Show fit	galectin 1
chr5_-_79874671 Show fit	21.45	ENSRNOT00000084563	Tnc NCBI RGD Ensembl Show fit	tenascin C
chr16_-_39719187 Show fit	21.40	ENSRNOT00000092971	Gpm6a NCBI RGD Ensembl Show fit	glycoprotein m6a
chr10_-_12916784 Show fit	21.33	ENSRNOT00000004589	Zfp13 NCBI RGD Ensembl Show fit	zinc finger protein 13
chr16_+_46731403 Show fit	21.19	ENSRNOT00000017624	Tenm3 NCBI RGD Ensembl Show fit	teneurin transmembrane protein 3
chr18_-_14016713 Show fit	21.13	ENSRNOT00000041125	Nol4 NCBI RGD Ensembl Show fit	nucleolar protein 4
chr16_+_22250470 Show fit	21.11	ENSRNOT00000015799	Lzts1 NCBI RGD Ensembl Show fit	leucine zipper tumor suppressor 1
chr7_-_98098268 Show fit	21.09	ENSRNOT00000010361	Fbxo32 NCBI RGD Ensembl Show fit	F-box protein 32
chr1_-_215373234 Show fit	20.98	ENSRNOT00000034299	AABR07006055.1 NCBI RGD Ensembl Show fit
chr1_+_198210525 Show fit	20.87	ENSRNOT00000026755	Ypel3 NCBI RGD Ensembl Show fit	yippee-like 3
chr10_-_47724499 Show fit	20.78	ENSRNOT00000085011	Rnf112 NCBI RGD Ensembl Show fit	ring finger protein 112
chr1_+_164225934 Show fit	20.78	ENSRNOT00000034389	Map6 NCBI RGD Ensembl Show fit	microtubule-associated protein 6
chr10_-_81942188 Show fit	20.75	ENSRNOT00000003784	Wfikkn2 NCBI RGD Ensembl Show fit	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr12_-_25638797 Show fit	20.73	ENSRNOT00000002033	Gatsl2 NCBI RGD Ensembl Show fit	GATS protein-like 2
chr4_+_110699557 Show fit	20.72	ENSRNOT00000030588 ENSRNOT00000092261	Lrrtm4 NCBI RGD Ensembl Show fit	leucine rich repeat transmembrane neuronal 4
chr5_+_169181418 Show fit	20.53	ENSRNOT00000004508	Klhl21 NCBI RGD Ensembl Show fit	kelch-like family member 21
chr5_+_22380334 Show fit	20.45	ENSRNOT00000009744	Clvs1 NCBI RGD Ensembl Show fit	clavesin 1
chrX_-_107542510 Show fit	20.41	ENSRNOT00000074140	Rab9b NCBI RGD Ensembl Show fit	RAB9B, member RAS oncogene family
chr10_-_89338739 Show fit	20.35	ENSRNOT00000073923	Ptges3l NCBI RGD Ensembl Show fit	prostaglandin E synthase 3 like
chr17_-_88037034 Show fit	20.26	ENSRNOT00000080193 ENSRNOT00000034907	Prtfdc1 NCBI RGD Ensembl Show fit	phosphoribosyl transferase domain containing 1
chr6_+_58467254 Show fit	20.18	ENSRNOT00000065396	Etv1 NCBI RGD Ensembl Show fit	ets variant 1
chr6_-_67085390 Show fit	19.94	ENSRNOT00000083277	Nova1 NCBI RGD Ensembl Show fit	NOVA alternative splicing regulator 1
chr1_+_220446425 Show fit	19.86	ENSRNOT00000027339	LOC100911932 NCBI RGD Ensembl Show fit	endosialin-like
chrX_-_157013443 Show fit	19.80	ENSRNOT00000082711	Srpk3 NCBI RGD Ensembl Show fit	SRSF protein kinase 3
chr15_+_48674380 Show fit	19.37	ENSRNOT00000018762	Fbxo16 NCBI RGD Ensembl Show fit	F-box protein 16
chr1_+_97632473 Show fit	19.34	ENSRNOT00000023671	Vstm2b NCBI RGD Ensembl Show fit	V-set and transmembrane domain containing 2B
chr4_+_184019087 Show fit	19.28	ENSRNOT00000055435	Bicd1 NCBI RGD Ensembl Show fit	BICD cargo adaptor 1
chr1_+_189665976 Show fit	19.10	ENSRNOT00000033673	Lyrm1 NCBI RGD Ensembl Show fit	LYR motif containing 1
chr1_+_255185629 Show fit	19.07	ENSRNOT00000083002	Hectd2 NCBI RGD Ensembl Show fit	HECT domain E3 ubiquitin protein ligase 2
chr4_-_153373649 Show fit	19.06	ENSRNOT00000016495	Atp6v1e1 NCBI RGD Ensembl Show fit	ATPase H+ transporting V1 subunit E1
chr5_+_151692108 Show fit	19.06	ENSRNOT00000086144	Fam46b NCBI RGD Ensembl Show fit	family with sequence similarity 46, member B
chr14_+_36071376 Show fit	19.02	ENSRNOT00000082183	Lnx1 NCBI RGD Ensembl Show fit	ligand of numb-protein X 1
chr7_+_11383116 Show fit	19.02	ENSRNOT00000066348	Nmrk2 NCBI RGD Ensembl Show fit	nicotinamide riboside kinase 2
chr11_-_88038518 Show fit	18.95	ENSRNOT00000051991	Rimbp3 NCBI RGD Ensembl Show fit	RIMS binding protein 3
chrX_+_1297099 Show fit	18.95	ENSRNOT00000013522	Elk1 NCBI RGD Ensembl Show fit	ELK1, ETS transcription factor

Network of associatons between targets according to the STRING database.

First level regulatory network of Myog_Tcf12

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
37.5	112.4	GO:0055073	cadmium ion homeostasis(GO:0055073) regulation of lysosomal membrane permeability(GO:0097213) positive regulation of lysosomal membrane permeability(GO:0097214) regulation of hydrogen peroxide catabolic process(GO:2000295)
36.6	146.3	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
25.7	103.0	GO:0036309	protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
21.7	65.1	GO:1904879	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
19.9	59.6	GO:0032430	positive regulation of phospholipase A2 activity(GO:0032430)
19.8	59.5	GO:0006480	N-terminal protein amino acid methylation(GO:0006480)
18.8	56.4	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
18.5	73.8	GO:0016554	cytidine to uridine editing(GO:0016554)
16.0	79.8	GO:0021966	corticospinal neuron axon guidance(GO:0021966)
14.7	117.9	GO:0051694	pointed-end actin filament capping(GO:0051694)
13.6	40.9	GO:0032972	regulation of muscle filament sliding speed(GO:0032972)
13.4	80.1	GO:1990573	potassium ion import across plasma membrane(GO:1990573)
12.6	50.4	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
12.2	61.2	GO:0098970	receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) NMDA selective glutamate receptor signaling pathway(GO:0098989) neurotransmitter receptor diffusion trapping(GO:0099628)
12.0	59.8	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
10.8	86.6	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
10.7	32.0	GO:1900186	negative regulation of clathrin-mediated endocytosis(GO:1900186) negative regulation of synaptic vesicle recycling(GO:1903422)
10.7	53.3	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
10.0	30.1	GO:0021678	third ventricle development(GO:0021678)
9.9	39.5	GO:1990523	bone regeneration(GO:1990523)
9.6	66.9	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
9.4	37.8	GO:0098961	dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
8.7	34.8	GO:0021586	pons maturation(GO:0021586)
8.6	25.7	GO:2001226	negative regulation of chloride transport(GO:2001226)
8.6	77.2	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
8.6	179.7	GO:2001014	regulation of skeletal muscle cell differentiation(GO:2001014)
8.1	32.5	GO:0031179	peptide modification(GO:0031179)
8.1	72.9	GO:0036376	sodium ion export from cell(GO:0036376) regulation of cardiac muscle cell membrane potential(GO:0086036)
8.0	64.3	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
7.9	47.6	GO:0051343	positive regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051343) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
7.8	23.4	GO:0061152	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
7.7	31.0	GO:2000255	negative regulation of male germ cell proliferation(GO:2000255)
7.6	22.8	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
7.4	29.7	GO:0003219	cardiac right ventricle formation(GO:0003219)
7.2	28.6	GO:1903999	negative regulation of eating behavior(GO:1903999)
6.9	34.3	GO:0061591	calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
6.8	20.3	GO:0006178	guanine salvage(GO:0006178) GMP catabolic process(GO:0046038) guanine biosynthetic process(GO:0046099)
6.7	33.7	GO:0030311	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
6.6	26.5	GO:0048687	positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
6.4	38.6	GO:0045113	regulation of integrin biosynthetic process(GO:0045113)
6.4	38.3	GO:0032286	central nervous system myelin maintenance(GO:0032286)
6.2	18.7	GO:0043314	negative regulation of neutrophil degranulation(GO:0043314)
5.6	22.5	GO:1904428	negative regulation of tubulin deacetylation(GO:1904428)
5.6	39.0	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
5.6	16.7	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
5.5	22.1	GO:1904204	regulation of skeletal muscle hypertrophy(GO:1904204)
5.5	27.5	GO:0060449	bud elongation involved in lung branching(GO:0060449)
5.5	16.4	GO:2000620	positive regulation of histone H4-K16 acetylation(GO:2000620)
5.4	59.0	GO:0048739	cardiac muscle fiber development(GO:0048739)
5.4	21.4	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
5.3	42.2	GO:0015871	choline transport(GO:0015871)
5.2	36.7	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
5.1	35.9	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
5.1	15.4	GO:0060825	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
4.9	38.8	GO:0035900	response to isolation stress(GO:0035900)
4.8	19.3	GO:1900736	regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
4.7	14.1	GO:0015688	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
4.7	55.9	GO:0071316	cellular response to nicotine(GO:0071316)
4.6	22.8	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
4.3	17.1	GO:1904426	positive regulation of GTP binding(GO:1904426)
4.3	29.9	GO:0072221	distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
4.3	21.3	GO:0010728	regulation of hydrogen peroxide biosynthetic process(GO:0010728)
4.3	8.5	GO:0001983	baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
4.2	8.5	GO:1903286	regulation of potassium ion import(GO:1903286)
4.2	21.1	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
4.2	12.6	GO:0070494	regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
4.2	16.7	GO:0043397	corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
4.1	16.2	GO:1902730	positive regulation of proteoglycan biosynthetic process(GO:1902730)
4.0	16.1	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
4.0	12.0	GO:0021917	pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
4.0	15.9	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
3.9	31.3	GO:0097113	AMPA glutamate receptor clustering(GO:0097113)
3.9	11.7	GO:0061146	ureter maturation(GO:0035799) Peyer's patch morphogenesis(GO:0061146)
3.8	26.9	GO:0099525	presynaptic dense core granule exocytosis(GO:0099525)
3.8	19.0	GO:0072061	inner medullary collecting duct development(GO:0072061)
3.8	22.5	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
3.6	10.9	GO:1904954	regulation of collateral sprouting in absence of injury(GO:0048696) canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
3.6	17.9	GO:0090274	positive regulation of somatostatin secretion(GO:0090274)
3.5	10.4	GO:1904722	positive regulation of mRNA cleavage(GO:0031439) positive regulation of endoribonuclease activity(GO:1902380) positive regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904722)
3.4	78.3	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
3.4	47.6	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
3.4	3.4	GO:2000541	positive regulation of synaptic growth at neuromuscular junction(GO:0045887) regulation of protein geranylgeranylation(GO:2000539) positive regulation of protein geranylgeranylation(GO:2000541)
3.2	28.9	GO:0048664	neuron fate determination(GO:0048664)
3.2	76.4	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
3.1	12.5	GO:0035965	cardiolipin acyl-chain remodeling(GO:0035965)
3.1	12.4	GO:0002159	desmosome assembly(GO:0002159)
3.0	81.7	GO:0002026	regulation of the force of heart contraction(GO:0002026)
3.0	24.1	GO:2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
2.9	8.8	GO:1902269	positive regulation of polyamine transmembrane transport(GO:1902269)
2.9	17.6	GO:0010649	regulation of cell communication by electrical coupling(GO:0010649)
2.8	109.2	GO:0003009	skeletal muscle contraction(GO:0003009)
2.8	30.6	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
2.8	16.6	GO:0046959	habituation(GO:0046959)
2.7	16.0	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
2.7	18.6	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
2.7	8.0	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)
2.7	13.3	GO:0048133	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
2.6	21.2	GO:0097264	self proteolysis(GO:0097264)
2.6	41.7	GO:1901663	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
2.5	24.9	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
2.5	9.9	GO:0051542	elastin biosynthetic process(GO:0051542)
2.4	9.8	GO:0097401	synaptic vesicle lumen acidification(GO:0097401)
2.4	9.5	GO:0061056	sclerotome development(GO:0061056)
2.4	35.7	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
2.4	26.0	GO:1903817	negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
2.3	14.0	GO:0033564	anterior/posterior axon guidance(GO:0033564)
2.3	16.2	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
2.3	6.9	GO:0015966	MAPK import into nucleus(GO:0000189) diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
2.2	2.2	GO:0035262	gonad morphogenesis(GO:0035262)
2.2	11.1	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
2.2	28.8	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
2.2	39.4	GO:0001573	ganglioside metabolic process(GO:0001573)
2.1	14.9	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
2.1	25.5	GO:0046069	cGMP catabolic process(GO:0046069)
2.1	6.4	GO:0006713	glucocorticoid catabolic process(GO:0006713)
2.1	8.5	GO:0045105	intermediate filament polymerization or depolymerization(GO:0045105)
2.1	18.7	GO:0032596	protein transport into membrane raft(GO:0032596)
2.1	12.4	GO:0010966	regulation of phosphate transport(GO:0010966)
2.0	30.7	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
2.0	8.2	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
2.0	56.6	GO:0034260	negative regulation of GTPase activity(GO:0034260)
2.0	6.0	GO:0002036	regulation of L-glutamate transport(GO:0002036)
2.0	11.8	GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
2.0	7.8	GO:0032364	oxygen homeostasis(GO:0032364)
2.0	13.7	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
2.0	9.8	GO:0014883	transition between fast and slow fiber(GO:0014883)
1.9	119.3	GO:1901379	regulation of potassium ion transmembrane transport(GO:1901379)
1.9	28.0	GO:0055003	cardiac myofibril assembly(GO:0055003)
1.9	14.8	GO:0097151	positive regulation of inhibitory postsynaptic potential(GO:0097151)
1.8	9.2	GO:0001661	conditioned taste aversion(GO:0001661)
1.8	25.8	GO:0051043	regulation of membrane protein ectodomain proteolysis(GO:0051043)
1.8	5.4	GO:0010609	mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
1.8	3.5	GO:0097069	cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
1.7	6.9	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
1.7	24.2	GO:0036065	fucosylation(GO:0036065)
1.7	3.5	GO:0034486	vacuolar transmembrane transport(GO:0034486) chaperone-mediated protein transport involved in chaperone-mediated autophagy(GO:0061741)
1.7	22.4	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
1.7	10.3	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
1.7	5.0	GO:1901252	regulation of intracellular transport of viral material(GO:1901252)
1.7	5.0	GO:0010133	proline catabolic process to glutamate(GO:0010133)
1.6	44.2	GO:0095500	acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
1.6	14.7	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
1.6	32.5	GO:0014741	negative regulation of muscle hypertrophy(GO:0014741)
1.6	12.7	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
1.5	10.8	GO:0017062	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
1.5	38.5	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
1.5	4.6	GO:0043605	cellular amide catabolic process(GO:0043605)
1.5	6.1	GO:0035513	oxidative RNA demethylation(GO:0035513) oxidative single-stranded DNA demethylation(GO:0035552) oxidative single-stranded RNA demethylation(GO:0035553)
1.5	22.2	GO:0036315	cellular response to sterol(GO:0036315)
1.5	5.9	GO:0042339	keratan sulfate metabolic process(GO:0042339)
1.5	19.0	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
1.4	2.9	GO:0071336	regulation of hair follicle cell proliferation(GO:0071336)
1.4	4.2	GO:1901143	insulin catabolic process(GO:1901143)
1.4	7.0	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
1.4	4.1	GO:0018199	peptidyl-glutamine modification(GO:0018199)
1.4	25.9	GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
1.4	67.9	GO:0043392	negative regulation of DNA binding(GO:0043392)
1.4	14.9	GO:0007258	JUN phosphorylation(GO:0007258)
1.3	17.5	GO:0035493	SNARE complex assembly(GO:0035493)
1.3	26.6	GO:0048745	smooth muscle tissue development(GO:0048745)
1.3	2.6	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
1.3	16.7	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
1.3	6.4	GO:0045218	zonula adherens maintenance(GO:0045218)
1.3	10.2	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
1.3	33.0	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
1.3	6.3	GO:0055119	relaxation of cardiac muscle(GO:0055119) regulation of relaxation of cardiac muscle(GO:1901897)
1.3	8.8	GO:0048227	plasma membrane to endosome transport(GO:0048227)
1.2	23.7	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
1.2	27.4	GO:0045109	intermediate filament organization(GO:0045109)
1.2	31.2	GO:0006471	protein ADP-ribosylation(GO:0006471)
1.2	14.8	GO:0099558	maintenance of synapse structure(GO:0099558)
1.2	6.2	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
1.2	7.3	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
1.2	21.8	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
1.2	17.9	GO:0006516	glycoprotein catabolic process(GO:0006516)
1.2	15.5	GO:2000251	positive regulation of actin cytoskeleton reorganization(GO:2000251)
1.2	24.9	GO:0051593	response to folic acid(GO:0051593)
1.2	4.7	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
1.2	10.7	GO:0021942	radial glia guided migration of Purkinje cell(GO:0021942)
1.1	6.8	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
1.1	20.1	GO:0016486	peptide hormone processing(GO:0016486)
1.1	16.8	GO:0032095	regulation of response to food(GO:0032095)
1.0	12.6	GO:1900745	positive regulation of p38MAPK cascade(GO:1900745)
1.0	10.4	GO:0098719	sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
1.0	14.4	GO:0043252	sodium-independent organic anion transport(GO:0043252)
1.0	9.2	GO:1901678	heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
1.0	3.0	GO:1990402	embryonic liver development(GO:1990402)
1.0	34.3	GO:0035176	social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
1.0	10.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
1.0	44.3	GO:0055013	cardiac muscle cell development(GO:0055013)
1.0	2.9	GO:0051142	positive regulation of memory T cell differentiation(GO:0043382) regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142) regulation of T-helper 17 cell lineage commitment(GO:2000328)
1.0	1.9	GO:0019086	late viral transcription(GO:0019086)
0.9	6.6	GO:0007290	spermatid nucleus elongation(GO:0007290)
0.9	2.8	GO:1903862	positive regulation of oxidative phosphorylation(GO:1903862)
0.9	55.4	GO:0046847	filopodium assembly(GO:0046847)
0.9	9.1	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.9	14.1	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.9	7.0	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
0.9	13.9	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.9	18.9	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.8	5.9	GO:0035635	entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.8	5.8	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.8	9.1	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.8	11.3	GO:0048199	vesicle targeting, to, from or within Golgi(GO:0048199)
0.8	4.8	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.8	12.5	GO:0008090	retrograde axonal transport(GO:0008090)
0.8	10.1	GO:0021860	pyramidal neuron development(GO:0021860)
0.8	17.6	GO:0022011	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.8	38.2	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.8	8.4	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.7	2.2	GO:1901098	positive regulation of autophagosome maturation(GO:1901098)
0.7	11.7	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.7	2.9	GO:0044211	CTP salvage(GO:0044211)
0.7	34.0	GO:0043462	regulation of ATPase activity(GO:0043462)
0.7	5.8	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.7	17.7	GO:0042775	mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.7	24.6	GO:0044380	protein localization to cytoskeleton(GO:0044380)
0.7	7.0	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.7	34.3	GO:0080171	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.7	5.6	GO:0033690	positive regulation of osteoblast proliferation(GO:0033690)
0.7	5.6	GO:0042118	endothelial cell activation(GO:0042118)
0.7	16.2	GO:0006779	porphyrin-containing compound biosynthetic process(GO:0006779)
0.7	10.7	GO:0021554	optic nerve development(GO:0021554)
0.7	36.9	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.7	72.1	GO:1902600	hydrogen ion transmembrane transport(GO:1902600)
0.7	11.2	GO:0031581	hemidesmosome assembly(GO:0031581)
0.7	2.0	GO:0034034	coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) fatty-acyl-CoA catabolic process(GO:0036115) malonyl-CoA metabolic process(GO:2001293)
0.7	7.9	GO:0042407	cristae formation(GO:0042407)
0.6	5.5	GO:0045634	regulation of melanocyte differentiation(GO:0045634)
0.6	3.1	GO:0016559	peroxisome fission(GO:0016559)
0.6	2.4	GO:0045903	positive regulation of translational fidelity(GO:0045903)
0.6	9.5	GO:0034587	piRNA metabolic process(GO:0034587)
0.6	45.7	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.6	0.6	GO:0014908	myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.6	26.5	GO:0042398	cellular modified amino acid biosynthetic process(GO:0042398)
0.6	11.7	GO:0035116	embryonic hindlimb morphogenesis(GO:0035116)
0.5	16.0	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.5	4.2	GO:0043586	tongue development(GO:0043586)
0.5	40.9	GO:0050807	regulation of synapse organization(GO:0050807)
0.5	3.4	GO:2000002	negative regulation of DNA damage checkpoint(GO:2000002)
0.5	2.0	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
0.5	9.2	GO:0021511	spinal cord patterning(GO:0021511)
0.5	1.9	GO:1901837	negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.5	13.0	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.5	3.3	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.5	6.0	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
0.5	5.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.5	2.3	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.5	9.5	GO:0030252	growth hormone secretion(GO:0030252)
0.4	5.7	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.4	7.4	GO:0061098	positive regulation of protein tyrosine kinase activity(GO:0061098)
0.4	15.2	GO:0060612	adipose tissue development(GO:0060612)
0.4	54.4	GO:0007519	skeletal muscle tissue development(GO:0007519)
0.4	0.8	GO:0050968	detection of chemical stimulus involved in sensory perception of pain(GO:0050968) regulation of establishment of blood-brain barrier(GO:0090210)
0.4	6.7	GO:0031116	positive regulation of microtubule polymerization(GO:0031116)
0.4	10.1	GO:0045840	positive regulation of mitotic nuclear division(GO:0045840)
0.4	5.4	GO:0021799	cerebral cortex radially oriented cell migration(GO:0021799)
0.4	1.6	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.4	15.4	GO:0009250	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.4	10.9	GO:0046785	microtubule polymerization(GO:0046785)
0.4	4.1	GO:0006013	mannose metabolic process(GO:0006013)
0.4	8.5	GO:0010842	retina layer formation(GO:0010842)
0.4	36.1	GO:0050808	synapse organization(GO:0050808)
0.4	4.6	GO:0021694	cerebellar Purkinje cell layer formation(GO:0021694)
0.4	2.8	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.4	8.1	GO:0030261	chromosome condensation(GO:0030261)
0.4	1.8	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.3	19.8	GO:0006096	glycolytic process(GO:0006096)
0.3	1.8	GO:2001053	regulation of mesenchymal cell apoptotic process(GO:2001053) negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.3	2.9	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.3	7.6	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.3	8.7	GO:0035902	response to immobilization stress(GO:0035902)
0.3	4.6	GO:0036475	neuron death in response to oxidative stress(GO:0036475)
0.3	11.0	GO:0000186	activation of MAPKK activity(GO:0000186)
0.3	14.3	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.3	4.3	GO:0045103	intermediate filament-based process(GO:0045103)
0.3	17.1	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.2	1.0	GO:0060023	soft palate development(GO:0060023)
0.2	0.7	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2	9.0	GO:0016239	positive regulation of macroautophagy(GO:0016239)
0.2	2.4	GO:0045214	sarcomere organization(GO:0045214)
0.2	0.6	GO:1903925	hormone-mediated apoptotic signaling pathway(GO:0008628) cellular response to magnetism(GO:0071259) response to bisphenol A(GO:1903925)
0.2	1.5	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
0.2	6.6	GO:0035987	endodermal cell differentiation(GO:0035987)
0.2	2.7	GO:0045956	positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.2	18.3	GO:0007050	cell cycle arrest(GO:0007050)
0.2	3.0	GO:0022904	respiratory electron transport chain(GO:0022904)
0.2	0.6	GO:0030576	Cajal body organization(GO:0030576)
0.2	11.1	GO:0032418	lysosome localization(GO:0032418)
0.2	1.5	GO:0034244	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.2	15.5	GO:0043524	negative regulation of neuron apoptotic process(GO:0043524)
0.2	5.9	GO:0048168	regulation of neuronal synaptic plasticity(GO:0048168)
0.2	7.6	GO:0007131	reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.2	16.3	GO:0006457	protein folding(GO:0006457)
0.2	3.2	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.2	4.0	GO:0006730	one-carbon metabolic process(GO:0006730)
0.2	2.4	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.2	1.7	GO:0022038	corpus callosum development(GO:0022038)
0.2	2.2	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.2	2.4	GO:0031167	rRNA methylation(GO:0031167)
0.1	19.9	GO:0006813	potassium ion transport(GO:0006813)
0.1	0.6	GO:1901662	phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.1	0.4	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.1	2.8	GO:0009067	aspartate family amino acid biosynthetic process(GO:0009067)
0.1	0.7	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1	0.6	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.1	0.7	GO:0048820	hair follicle maturation(GO:0048820)
0.1	4.0	GO:0008306	associative learning(GO:0008306)
0.1	0.8	GO:0051255	spindle midzone assembly(GO:0051255)
0.1	0.4	GO:0031585	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585)
0.1	2.3	GO:0006303	double-strand break repair via nonhomologous end joining(GO:0006303)
0.1	1.1	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.1	1.8	GO:0001522	pseudouridine synthesis(GO:0001522)
0.1	0.4	GO:0046710	GDP metabolic process(GO:0046710)
0.1	0.2	GO:0090214	spongiotrophoblast layer developmental growth(GO:0090214)
0.0	2.8	GO:0090090	negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0	2.6	GO:0006171	cAMP biosynthetic process(GO:0006171)
0.0	0.7	GO:0021591	ventricular system development(GO:0021591)
0.0	1.1	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.1	GO:0010587	miRNA catabolic process(GO:0010587)
0.0	0.3	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	1.6	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
15.3	61.2	GO:0099524	region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
14.1	112.4	GO:0097450	astrocyte end-foot(GO:0097450)
14.0	55.9	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
13.1	39.4	GO:0034686	integrin alphav-beta8 complex(GO:0034686)
13.0	39.0	GO:0043511	inhibin-betaglycan-ActRII complex(GO:0034673) inhibin complex(GO:0043511)
12.7	38.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
12.2	72.9	GO:0044326	dendritic spine neck(GO:0044326)
11.6	34.8	GO:0098855	HCN channel complex(GO:0098855)
11.6	34.8	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
11.4	136.8	GO:0005861	troponin complex(GO:0005861)
11.2	56.2	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
9.5	47.6	GO:0042584	chromaffin granule membrane(GO:0042584)
9.1	54.8	GO:0097512	cardiac myofibril(GO:0097512)
8.7	52.0	GO:1990393	3M complex(GO:1990393)
8.6	34.3	GO:0005588	collagen type V trimer(GO:0005588)
6.8	27.0	GO:0097513	myosin II filament(GO:0097513)
6.4	19.3	GO:0033647	host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
6.1	122.0	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
5.8	17.5	GO:0070821	azurophil granule membrane(GO:0035577) tertiary granule membrane(GO:0070821)
5.8	298.1	GO:0031672	A band(GO:0031672)
5.7	17.1	GO:1990796	photoreceptor cell terminal bouton(GO:1990796)
5.2	62.1	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
5.1	30.7	GO:0033269	internode region of axon(GO:0033269)
4.9	63.5	GO:0005865	striated muscle thin filament(GO:0005865)
4.5	50.0	GO:0032009	early phagosome(GO:0032009)
4.4	8.9	GO:0044305	calyx of Held(GO:0044305)
3.5	101.6	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
3.3	9.8	GO:0071148	TEAD-1-YAP complex(GO:0071148)
2.9	20.5	GO:0005827	polar microtubule(GO:0005827)
2.8	8.3	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
2.8	13.8	GO:0070695	FHF complex(GO:0070695)
2.6	85.4	GO:0032839	dendrite cytoplasm(GO:0032839)
2.6	23.2	GO:0016461	unconventional myosin complex(GO:0016461)
2.5	10.2	GO:0043564	Ku70:Ku80 complex(GO:0043564)
2.5	29.7	GO:0005796	Golgi lumen(GO:0005796)
2.5	29.7	GO:0071564	npBAF complex(GO:0071564)
2.5	32.0	GO:0016342	catenin complex(GO:0016342)
2.4	7.3	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
2.4	44.9	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
2.4	244.8	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
2.3	16.2	GO:0008091	spectrin(GO:0008091)
2.2	17.9	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
2.2	11.0	GO:0097361	CIA complex(GO:0097361)
2.2	17.2	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
2.1	8.5	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
2.1	56.4	GO:0001891	phagocytic cup(GO:0001891)
2.1	34.9	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
1.9	239.4	GO:0030017	sarcomere(GO:0030017)
1.8	16.2	GO:0098644	complex of collagen trimers(GO:0098644)
1.7	44.9	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
1.7	19.0	GO:0002177	manchette(GO:0002177)
1.6	9.5	GO:0071547	piP-body(GO:0071547)
1.6	25.3	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
1.5	44.3	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
1.5	47.4	GO:0060077	inhibitory synapse(GO:0060077)
1.5	7.3	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
1.4	31.4	GO:1902711	GABA-A receptor complex(GO:1902711)
1.3	8.1	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
1.3	5.2	GO:0060053	neurofilament cytoskeleton(GO:0060053)
1.3	3.8	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
1.3	8.8	GO:0032584	growth cone membrane(GO:0032584)
1.2	18.4	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
1.2	18.8	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
1.1	7.9	GO:0061617	MICOS complex(GO:0061617)
1.1	18.8	GO:0005614	interstitial matrix(GO:0005614)
1.1	31.7	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
1.0	11.5	GO:0043083	synaptic cleft(GO:0043083)
1.0	70.3	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
1.0	3.0	GO:0045257	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) fumarate reductase complex(GO:0045283)
1.0	193.2	GO:0005802	trans-Golgi network(GO:0005802)
0.9	6.4	GO:0005915	zonula adherens(GO:0005915)
0.9	32.7	GO:0042734	presynaptic membrane(GO:0042734)
0.9	15.4	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.9	14.5	GO:0097440	apical dendrite(GO:0097440)
0.8	231.0	GO:0099572	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.8	0.8	GO:0032591	dendritic spine membrane(GO:0032591)
0.8	9.8	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.8	5.7	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.8	2.4	GO:0034457	Mpp10 complex(GO:0034457)
0.8	12.9	GO:0030061	mitochondrial crista(GO:0030061)
0.8	19.9	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.8	6.3	GO:0031527	filopodium membrane(GO:0031527)
0.8	4.6	GO:1990696	stereocilia ankle link complex(GO:0002142) USH2 complex(GO:1990696)
0.8	65.4	GO:0043197	dendritic spine(GO:0043197)
0.8	40.7	GO:0005581	collagen trimer(GO:0005581)
0.7	17.5	GO:0035371	microtubule plus-end(GO:0035371)
0.7	72.2	GO:0031225	anchored component of membrane(GO:0031225)
0.7	11.2	GO:0043034	costamere(GO:0043034)
0.7	3.5	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.7	14.5	GO:0000145	exocyst(GO:0000145)
0.6	6.2	GO:0031258	lamellipodium membrane(GO:0031258)
0.6	2.4	GO:0005927	muscle tendon junction(GO:0005927)
0.6	29.4	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.6	7.6	GO:0035686	sperm fibrous sheath(GO:0035686)
0.5	4.4	GO:0016272	prefoldin complex(GO:0016272)
0.5	10.9	GO:0070469	respiratory chain(GO:0070469)
0.5	4.6	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.5	89.7	GO:0043209	myelin sheath(GO:0043209)
0.5	12.5	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.5	30.1	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.5	10.8	GO:0032809	neuronal cell body membrane(GO:0032809)
0.5	11.7	GO:0034707	chloride channel complex(GO:0034707)
0.5	4.1	GO:0030673	axolemma(GO:0030673)
0.4	8.8	GO:0031985	Golgi cisterna(GO:0031985)
0.4	4.2	GO:0031597	cytosolic proteasome complex(GO:0031597)
0.4	42.1	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.4	18.1	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.4	39.0	GO:0016605	PML body(GO:0016605)
0.4	86.6	GO:0043235	receptor complex(GO:0043235)
0.4	22.2	GO:0045211	postsynaptic membrane(GO:0045211)
0.4	12.4	GO:0005844	polysome(GO:0005844)
0.4	9.2	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.3	16.4	GO:0000795	synaptonemal complex(GO:0000795)
0.3	2.7	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.3	3.4	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.3	3.4	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.3	9.5	GO:0016459	myosin complex(GO:0016459)
0.3	12.2	GO:0045335	phagocytic vesicle(GO:0045335)
0.3	7.3	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.3	2.7	GO:0031045	dense core granule(GO:0031045)
0.3	50.2	GO:0022626	cytosolic ribosome(GO:0022626)
0.3	5.7	GO:0005680	anaphase-promoting complex(GO:0005680)
0.3	1.9	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.3	11.1	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.3	8.5	GO:0043195	terminal bouton(GO:0043195)
0.3	6.3	GO:0043679	axon terminus(GO:0043679)
0.2	2.2	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.2	7.0	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.2	0.4	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110)
0.2	39.5	GO:0005874	microtubule(GO:0005874)
0.1	43.6	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.1	9.9	GO:0005604	basement membrane(GO:0005604)
0.1	4.7	GO:0035869	ciliary transition zone(GO:0035869)
0.1	3.3	GO:0031201	SNARE complex(GO:0031201)
0.1	11.5	GO:0072562	blood microparticle(GO:0072562)
0.1	1.5	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	5.8	GO:0045171	intercellular bridge(GO:0045171)
0.1	8.7	GO:0043204	perikaryon(GO:0043204)
0.1	1.8	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	1.4	GO:0034709	methylosome(GO:0034709)
0.0	16.7	GO:0005635	nuclear envelope(GO:0005635)
0.0	0.4	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.4	GO:0044306	neuron projection terminus(GO:0044306)
0.0	1.3	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	6.2	GO:0030425	dendrite(GO:0030425)
0.0	1.0	GO:1990391	DNA repair complex(GO:1990391)
0.0	0.0	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0	3.0	GO:0010008	endosome membrane(GO:0010008)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.6	GO:0016592	mediator complex(GO:0016592)
0.0	0.6	GO:0015030	Cajal body(GO:0015030)
0.0	0.7	GO:0005930	axoneme(GO:0005930) ciliary plasm(GO:0097014)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
22.0	66.0	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
19.8	59.5	GO:0071885	N-terminal protein N-methyltransferase activity(GO:0071885)
16.0	79.8	GO:0086062	voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
15.9	47.6	GO:0031997	N-terminal myristoylation domain binding(GO:0031997) calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099567)
15.5	15.5	GO:0099510	calcium ion binding involved in regulation of cytosolic calcium ion concentration(GO:0099510)
14.0	55.9	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
12.4	86.6	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
12.3	73.8	GO:0004126	cytidine deaminase activity(GO:0004126)
11.0	55.2	GO:0031014	troponin T binding(GO:0031014)
10.9	65.1	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
10.3	71.8	GO:0034711	inhibin binding(GO:0034711)
10.2	40.9	GO:0030172	troponin C binding(GO:0030172)
10.2	112.4	GO:0046870	cadmium ion binding(GO:0046870)
9.8	49.1	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
9.5	47.6	GO:0030348	syntaxin-3 binding(GO:0030348)
9.3	74.2	GO:0005095	GTPase inhibitor activity(GO:0005095)
9.1	45.3	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
8.8	61.3	GO:0001849	complement component C1q binding(GO:0001849)
8.4	33.7	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
8.3	115.8	GO:0005523	tropomyosin binding(GO:0005523)
8.1	32.5	GO:0016842	amidine-lyase activity(GO:0016842)
7.7	23.0	GO:0001847	opsonin receptor activity(GO:0001847)
7.4	73.6	GO:0003680	AT DNA binding(GO:0003680)
7.2	35.8	GO:0048039	ubiquinone binding(GO:0048039)
7.1	42.8	GO:0005030	neurotrophin receptor activity(GO:0005030)
6.9	20.8	GO:2001070	starch binding(GO:2001070)
6.8	20.3	GO:0051538	3 iron, 4 sulfur cluster binding(GO:0051538)
6.5	78.0	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
6.4	19.3	GO:0031871	proteinase activated receptor binding(GO:0031871)
6.4	38.5	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
6.4	25.5	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
6.0	54.0	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
5.9	77.2	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
5.7	39.9	GO:0004111	creatine kinase activity(GO:0004111)
5.4	59.7	GO:0042577	lipid phosphatase activity(GO:0042577)
5.2	36.5	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
5.2	72.9	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
5.1	25.7	GO:0004690	cyclic nucleotide-dependent protein kinase activity(GO:0004690)
4.9	59.1	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
4.9	39.4	GO:1990430	extracellular matrix protein binding(GO:1990430)
4.8	28.6	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
4.7	61.1	GO:0070097	delta-catenin binding(GO:0070097)
4.7	285.3	GO:0015459	potassium channel regulator activity(GO:0015459)
4.6	22.8	GO:0004351	glutamate decarboxylase activity(GO:0004351)
4.3	12.9	GO:0008142	oxysterol binding(GO:0008142)
4.3	163.9	GO:0008307	structural constituent of muscle(GO:0008307)
4.1	101.4	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
4.0	24.2	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
3.6	25.4	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
3.6	21.6	GO:0048030	disaccharide binding(GO:0048030)
3.5	28.0	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
3.5	34.8	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
3.5	10.4	GO:0031249	denatured protein binding(GO:0031249)
3.3	10.0	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
3.2	32.1	GO:0034190	apolipoprotein receptor binding(GO:0034190)
3.2	99.0	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
3.1	12.5	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
3.0	26.9	GO:0019992	diacylglycerol binding(GO:0019992)
2.9	8.8	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
2.8	16.9	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
2.8	14.0	GO:0005042	netrin receptor activity(GO:0005042)
2.8	8.4	GO:0022841	potassium ion leak channel activity(GO:0022841)
2.8	80.5	GO:0003785	actin monomer binding(GO:0003785)
2.7	16.1	GO:0016413	O-acetyltransferase activity(GO:0016413)
2.7	21.4	GO:0045545	syndecan binding(GO:0045545)
2.6	26.5	GO:0019855	calcium channel inhibitor activity(GO:0019855)
2.6	15.4	GO:0090599	alpha-glucosidase activity(GO:0090599)
2.4	34.0	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
2.2	42.2	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
2.2	13.0	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
2.1	30.0	GO:0016805	dipeptidase activity(GO:0016805)
2.1	17.1	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
2.1	100.5	GO:0019213	deacetylase activity(GO:0019213)
2.1	6.4	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
2.1	65.6	GO:0043394	proteoglycan binding(GO:0043394)
2.1	14.7	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
2.1	51.5	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
2.1	10.3	GO:0035473	lipase binding(GO:0035473)
1.9	5.8	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
1.9	24.9	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
1.9	45.3	GO:0051428	peptide hormone receptor binding(GO:0051428)
1.9	39.5	GO:0048018	receptor agonist activity(GO:0048018)
1.9	13.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
1.9	5.6	GO:0004687	myosin light chain kinase activity(GO:0004687)
1.8	73.0	GO:0015485	cholesterol binding(GO:0015485)
1.8	12.5	GO:0045504	dynein heavy chain binding(GO:0045504)
1.7	3.5	GO:0017098	sulfonylurea receptor binding(GO:0017098)
1.7	10.2	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
1.7	5.0	GO:0004657	proline dehydrogenase activity(GO:0004657)
1.6	12.9	GO:0005169	neurotrophin TRKB receptor binding(GO:0005169)
1.6	34.3	GO:0017128	phospholipid scramblase activity(GO:0017128)
1.6	12.4	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
1.5	12.3	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
1.5	16.8	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
1.5	6.1	GO:0035515	DNA demethylase activity(GO:0035514) oxidative RNA demethylase activity(GO:0035515)
1.5	18.3	GO:0019215	intermediate filament binding(GO:0019215)
1.5	33.0	GO:0017075	syntaxin-1 binding(GO:0017075)
1.5	14.9	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.5	7.3	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
1.5	36.4	GO:0017091	AU-rich element binding(GO:0017091)
1.4	5.5	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
1.4	33.0	GO:0030371	translation repressor activity(GO:0030371)
1.4	6.8	GO:0050692	DBD domain binding(GO:0050692)
1.2	29.2	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
1.2	31.4	GO:0004890	GABA-A receptor activity(GO:0004890)
1.2	34.6	GO:0071855	neuropeptide receptor binding(GO:0071855)
1.2	24.9	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
1.1	31.9	GO:0005501	retinoid binding(GO:0005501)
1.1	71.5	GO:0019888	protein phosphatase regulator activity(GO:0019888)
1.1	35.0	GO:0051879	Hsp90 protein binding(GO:0051879)
1.1	29.4	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
1.1	28.7	GO:0017080	sodium channel regulator activity(GO:0017080)
1.0	10.4	GO:0015386	potassium:proton antiporter activity(GO:0015386)
1.0	14.4	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
1.0	9.2	GO:0015232	heme transporter activity(GO:0015232)
1.0	58.3	GO:0048306	calcium-dependent protein binding(GO:0048306)
1.0	5.9	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
1.0	41.3	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.9	29.5	GO:0001540	beta-amyloid binding(GO:0001540)
0.9	174.1	GO:0003729	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.9	20.3	GO:0005112	Notch binding(GO:0005112)
0.9	14.9	GO:0017049	GTP-Rho binding(GO:0017049)
0.9	29.7	GO:0031369	translation initiation factor binding(GO:0031369)
0.9	10.3	GO:0019208	phosphatase regulator activity(GO:0019208)
0.8	19.9	GO:0004383	guanylate cyclase activity(GO:0004383)
0.8	2.3	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.7	12.6	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.6	18.8	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.6	10.9	GO:0004806	triglyceride lipase activity(GO:0004806)
0.6	1.8	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.6	2.4	GO:0016433	rRNA (adenine) methyltransferase activity(GO:0016433)
0.6	17.0	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.6	2.9	GO:0004849	uridine kinase activity(GO:0004849)
0.6	6.9	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.6	20.9	GO:0005484	SNAP receptor activity(GO:0005484)
0.5	47.4	GO:0051082	unfolded protein binding(GO:0051082)
0.5	1.6	GO:0048156	tau protein binding(GO:0048156)
0.5	4.7	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.5	44.9	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.5	33.0	GO:0019003	GDP binding(GO:0019003)
0.5	21.5	GO:0035591	signaling adaptor activity(GO:0035591)
0.5	3.1	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
0.5	8.5	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.5	23.3	GO:0050840	extracellular matrix binding(GO:0050840)
0.5	3.2	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.5	2.3	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.4	9.5	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.4	11.0	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.4	0.8	GO:0097603	temperature-gated ion channel activity(GO:0097603)
0.4	11.5	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.4	16.7	GO:0005518	collagen binding(GO:0005518)
0.4	3.5	GO:0033691	sialic acid binding(GO:0033691)
0.3	1.4	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.3	10.7	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.3	21.6	GO:0005262	calcium channel activity(GO:0005262)
0.3	35.3	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.3	1.9	GO:0097322	7SK snRNA binding(GO:0097322)
0.3	4.0	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.3	31.1	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.3	94.3	GO:0015631	tubulin binding(GO:0015631)
0.3	4.1	GO:0004559	alpha-mannosidase activity(GO:0004559)
0.3	2.6	GO:0045294	alpha-catenin binding(GO:0045294)
0.2	14.7	GO:0051087	chaperone binding(GO:0051087)
0.2	27.4	GO:0015171	amino acid transmembrane transporter activity(GO:0015171)
0.2	2.8	GO:0005243	gap junction channel activity(GO:0005243)
0.2	3.0	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2	80.3	GO:0004674	protein serine/threonine kinase activity(GO:0004674)
0.2	1.1	GO:0030280	structural constituent of epidermis(GO:0030280)
0.2	12.7	GO:0004536	deoxyribonuclease activity(GO:0004536)
0.2	15.6	GO:0008081	phosphoric diester hydrolase activity(GO:0008081)
0.2	9.9	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.2	27.8	GO:0020037	heme binding(GO:0020037)
0.2	13.6	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.2	0.7	GO:0004127	cytidylate kinase activity(GO:0004127)
0.2	2.7	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.2	75.2	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.2	0.6	GO:1990239	steroid hormone binding(GO:1990239)
0.2	3.7	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
0.2	78.2	GO:0005509	calcium ion binding(GO:0005509)
0.1	1.8	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.1	7.8	GO:0003774	motor activity(GO:0003774)
0.1	0.6	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.1	5.8	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.1	3.0	GO:0042169	SH2 domain binding(GO:0042169)
0.1	3.0	GO:0016769	transferase activity, transferring nitrogenous groups(GO:0016769)
0.1	3.8	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	2.0	GO:0016893	endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891) endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters(GO:0016893)
0.1	2.6	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.1	6.5	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1	20.7	GO:0030246	carbohydrate binding(GO:0030246)
0.1	1.6	GO:0051059	NF-kappaB binding(GO:0051059)
0.1	0.6	GO:0001671	ATPase activator activity(GO:0001671)
0.1	1.1	GO:0001594	trace-amine receptor activity(GO:0001594)
0.1	0.4	GO:0004385	guanylate kinase activity(GO:0004385)
0.1	5.2	GO:0016503	pheromone receptor activity(GO:0016503)
0.1	1.3	GO:0046875	ephrin receptor binding(GO:0046875)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.7	147.3	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
2.1	35.8	ST G ALPHA S PATHWAY	G alpha s Pathway
2.0	45.3	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
1.9	66.8	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
1.9	39.4	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
1.6	54.7	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
1.6	28.5	PID LPA4 PATHWAY	LPA4-mediated signaling events
1.3	37.7	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
1.1	12.6	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
1.1	63.9	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
1.1	15.8	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
1.0	16.8	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
1.0	34.1	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
1.0	21.4	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.8	36.4	PID AURORA B PATHWAY	Aurora B signaling
0.8	33.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.8	37.9	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.7	34.3	NABA COLLAGENS	Genes encoding collagen proteins
0.6	25.4	PID FOXO PATHWAY	FoxO family signaling
0.6	29.3	PID ATR PATHWAY	ATR signaling pathway
0.6	10.3	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.6	29.9	PID LKB1 PATHWAY	LKB1 signaling events
0.6	39.3	PID NOTCH PATHWAY	Notch signaling pathway
0.6	10.6	PID S1P S1P3 PATHWAY	S1P3 pathway
0.5	7.8	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.5	5.2	PID RAC1 PATHWAY	RAC1 signaling pathway
0.5	18.6	PID INSULIN PATHWAY	Insulin Pathway
0.5	89.9	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.4	132.6	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.4	3.5	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.4	10.3	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.4	11.7	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.4	15.3	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.4	11.8	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.4	10.0	PID RAS PATHWAY	Regulation of Ras family activation
0.4	10.3	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.4	19.4	PID CDC42 PATHWAY	CDC42 signaling events
0.3	7.5	PID RHOA PATHWAY	RhoA signaling pathway
0.2	3.9	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.2	5.6	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.2	3.5	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.2	8.6	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.2	6.7	PID P53 REGULATION PATHWAY	p53 pathway
0.2	6.5	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.2	11.8	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.2	2.3	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.1	4.7	PID AP1 PATHWAY	AP-1 transcription factor network
0.1	0.6	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
9.2	165.3	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
8.3	314.1	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
4.1	143.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
3.9	39.0	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
3.6	54.4	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
3.4	47.6	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
3.2	78.8	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
3.1	28.0	REACTOME DEFENSINS	Genes involved in Defensins
3.0	76.9	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
2.9	25.7	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
2.6	97.1	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
2.1	54.0	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
1.8	23.6	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
1.8	25.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
1.7	30.7	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
1.7	35.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
1.6	16.5	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
1.6	43.0	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
1.5	22.8	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
1.5	18.0	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
1.4	38.8	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
1.3	64.5	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
1.3	102.5	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
1.2	17.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
1.2	17.1	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
1.2	15.5	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
1.2	17.5	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
1.1	20.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
1.1	5.5	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
1.0	11.3	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.9	16.0	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.9	15.4	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.8	29.4	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.8	16.5	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.8	12.0	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.8	48.2	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.8	58.9	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.7	5.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.7	10.7	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.6	12.9	REACTOME KERATAN SULFATE KERATIN METABOLISM	Genes involved in Keratan sulfate/keratin metabolism
0.6	10.4	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
0.5	11.1	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.5	19.7	REACTOME PROTEIN FOLDING	Genes involved in Protein folding
0.5	10.1	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.4	2.9	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.4	5.8	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.4	8.5	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.4	7.8	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.4	3.5	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.4	5.7	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.3	3.8	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.3	5.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.3	14.5	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.3	2.9	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.3	10.0	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.3	3.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.3	3.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.3	2.3	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.3	3.4	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.3	4.8	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.3	11.3	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2	13.5	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.2	11.1	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.2	7.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.2	6.0	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2	2.8	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.2	1.8	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2	2.6	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2	8.7	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.2	5.8	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.2	2.8	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	10.4	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.1	0.6	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.1	7.1	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	1.9	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1	1.7	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.1	0.3	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	5.2	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	2.0	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	1.1	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.4	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER

Results for Myog_Tcf12

Z-value: 2.20

Motif logo

Transcription factors associated with Myog_Tcf12

Activity-expression correlation:

Activity profile of Myog_Tcf12 motif

Sorted Z-values of Myog_Tcf12 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Myog_Tcf12

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: