ISMARA results: Myf6

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Myf6

Z-value: 1.09

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Transcription factors associated with Myf6

Gene Symbol	Gene ID	Gene Info
Myf6 NCBI RGD Ensembl	ENSRNOG00000004878	myogenic factor 6

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Myf6	rn6_v1_chr7_-_49741540_49741540	-0.27	9.7e-07	Click!

Activity profile of Myf6 motif

Sorted Z-values of Myf6 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr1_-_31122093 Show fit	32.47	ENSRNOT00000016712	NEWGENE_1307525 NCBI RGD Ensembl Show fit	SOGA family member 3
chr1_-_13915594 Show fit	28.88	ENSRNOT00000015927	Arfgef3 NCBI RGD Ensembl Show fit	ARFGEF family member 3
chr15_+_50891127 Show fit	23.76	ENSRNOT00000020728	Stc1 NCBI RGD Ensembl Show fit	stanniocalcin 1
chr17_+_88215834 Show fit	23.27	ENSRNOT00000034098	Gpr158 NCBI RGD Ensembl Show fit	G protein-coupled receptor 158
chr3_+_71210301 Show fit	21.94	ENSRNOT00000006504	Fam171b NCBI RGD Ensembl Show fit	family with sequence similarity 171, member B
chr5_+_144634143 Show fit	20.99	ENSRNOT00000075558	RGD1563072 NCBI RGD Ensembl Show fit	similar to hypothetical protein FLJ38984
chr18_-_29015552 Show fit	18.50	ENSRNOT00000028713	Nrg2 NCBI RGD Ensembl Show fit	neuregulin 2
chr10_-_90151042 Show fit	18.45	ENSRNOT00000055187	Hdac5 NCBI RGD Ensembl Show fit	histone deacetylase 5
chr19_+_58823814 Show fit	18.32	ENSRNOT00000027058 ENSRNOT00000088626	Kcnk1 NCBI RGD Ensembl Show fit	potassium two pore domain channel subfamily K member 1
chr8_+_49676540 Show fit	18.13	ENSRNOT00000022032 ENSRNOT00000082205	Fxyd6 NCBI RGD Ensembl Show fit	FXYD domain-containing ion transport regulator 6

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Myf6

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	33.9	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
1.4	31.7	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
3.9	31.3	GO:0046959	habituation(GO:0046959)
2.3	29.3	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.3	26.2	GO:0007173	epidermal growth factor receptor signaling pathway(GO:0007173)
0.4	25.5	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
1.2	23.7	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
1.8	20.0	GO:0061042	vascular wound healing(GO:0061042)
6.4	19.3	GO:0060932	sinoatrial node cell development(GO:0060931) His-Purkinje system cell differentiation(GO:0060932)
4.7	18.8	GO:1901662	phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)

Showing 1 to 10 of 331 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	107.5	GO:0005887	integral component of plasma membrane(GO:0005887)
0.0	98.4	GO:0016021	integral component of membrane(GO:0016021)
0.8	84.5	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.3	43.5	GO:0008021	synaptic vesicle(GO:0008021)
0.2	40.6	GO:0005802	trans-Golgi network(GO:0005802)
0.2	40.3	GO:0045211	postsynaptic membrane(GO:0045211)
0.1	35.0	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.1	32.4	GO:0043025	neuronal cell body(GO:0043025)
1.8	28.9	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
1.2	26.6	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)

Showing 1 to 10 of 157 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
5.5	43.9	GO:0005095	GTPase inhibitor activity(GO:0005095)
1.1	37.7	GO:0017075	syntaxin-1 binding(GO:0017075)
1.2	31.7	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
6.1	30.7	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.7	28.7	GO:0015459	potassium channel regulator activity(GO:0015459)
0.7	28.6	GO:0017080	sodium channel regulator activity(GO:0017080)
1.0	28.5	GO:0008395	steroid hydroxylase activity(GO:0008395)
3.9	23.7	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.2	23.7	GO:0005178	integrin binding(GO:0005178)
0.2	22.6	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)

Showing 1 to 10 of 242 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	78.9	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.2	34.2	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2	31.4	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
1.3	27.9	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.8	20.9	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
1.0	20.5	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.7	20.1	ST ADRENERGIC	Adrenergic Pathway
0.4	19.7	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.3	19.5	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
1.0	18.5	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network

Showing 1 to 10 of 61 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
3.1	40.9	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.5	38.1	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.4	34.4	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
1.0	31.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
1.4	29.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
1.2	27.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.9	26.6	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.2	24.8	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.7	23.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	22.7	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors

Showing 1 to 10 of 104 entries

Results for Myf6

Z-value: 1.09

Motif logo

Transcription factors associated with Myf6

Activity-expression correlation:

Activity profile of Myf6 motif

Sorted Z-values of Myf6 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Myf6

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: