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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Myb

Z-value: 1.65

Motif logo

Transcription factors associated with Myb

Gene Symbol Gene ID Gene Info
ENSRNOG00000055858 MYB proto-oncogene, transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mybrn6_v1_chr1_-_16687817_166878170.172.2e-03Click!

Activity profile of Myb motif

Sorted Z-values of Myb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_42751330 103.63 ENSRNOT00000066478
ADAM metallopeptidase domain 2
chr19_+_24545318 90.52 ENSRNOT00000005071
calmegin
chr1_+_51619875 81.21 ENSRNOT00000023319
poly(A) binding protein, cytoplasmic 6
chr10_-_56530842 80.07 ENSRNOT00000077451

chr11_-_88038518 79.37 ENSRNOT00000051991
RIMS binding protein 3
chr1_+_102915191 78.85 ENSRNOT00000017851
lactate dehydrogenase C
chr6_+_136536736 78.85 ENSRNOT00000086594
tudor domain containing 9
chr10_+_56546710 78.74 ENSRNOT00000023003
Y box binding protein 2
chr2_-_187668677 73.39 ENSRNOT00000056898
ENSRNOT00000092563
TSSK6 activating co-chaperone
chr2_-_84531192 71.77 ENSRNOT00000065312
ENSRNOT00000090540
rhophilin associated tail protein 1-like
chr12_+_24367199 64.84 ENSRNOT00000001971
FK506 binding protein 6
chr16_-_7336335 64.30 ENSRNOT00000044991
PHD finger protein 7
chr9_+_19917603 62.08 ENSRNOT00000038239
tudor domain containing 6
chr10_+_72486152 61.36 ENSRNOT00000004193
similar to Chromodomain-helicase-DNA-binding protein 1 (CHD-1)
chr3_+_110618298 60.41 ENSRNOT00000012454
kinetochore-localized astrin/SPAG5 binding protein
chr19_+_21541742 59.90 ENSRNOT00000021095
ENSRNOT00000042077
ATP binding cassette subfamily C member 12
chr1_-_162713610 57.66 ENSRNOT00000018091
aquaporin 11
chr2_+_252263386 57.53 ENSRNOT00000092913
ENSRNOT00000084034
ENSRNOT00000041186
ENSRNOT00000092931
SSX family member 2 interacting protein
chr7_+_40316639 57.00 ENSRNOT00000080150
similar to hypothetical protein FLJ35821
chr2_+_208323882 55.36 ENSRNOT00000085178
transmembrane and immunoglobulin domain containing 3
chr4_+_157348020 52.52 ENSRNOT00000020803
cell division cycle associated 3
chr17_-_44595323 52.37 ENSRNOT00000086767
POM121 transmembrane nucleoporin-like 2
chr8_+_117170620 51.84 ENSRNOT00000075271
hypothetical LOC498675
chr17_-_43675934 51.70 ENSRNOT00000081345
histone cluster 1 H1 family member t
chr16_+_72139063 50.36 ENSRNOT00000023805
ADAM metallopeptidase domain 18
chr13_-_110257367 50.17 ENSRNOT00000005576
denticleless E3 ubiquitin protein ligase homolog
chr2_+_127538659 49.07 ENSRNOT00000093483
ENSRNOT00000058476
solute carrier family 25 member 31
chr4_+_148199102 48.91 ENSRNOT00000083563
zinc finger AN1-type containing 4
chr5_-_127273656 45.82 ENSRNOT00000057341
DMRT-like family B with proline-rich C-terminal, 1
chr10_-_70118194 44.51 ENSRNOT00000009944
chaperonin containing TCP1 subunit 6B
chr18_+_47659128 44.49 ENSRNOT00000051142
glycerol kinase-like 1
chr8_+_79054237 41.06 ENSRNOT00000077613
meiosis-specific nuclear structural 1
chr12_-_38274036 40.13 ENSRNOT00000063990
kinetochore associated 1
chr5_-_137265015 39.02 ENSRNOT00000036151
cell division cycle 20
chr10_-_84976170 37.65 ENSRNOT00000013542
leucine rich repeat containing 46
chr6_+_99433550 35.95 ENSRNOT00000079359
ENSRNOT00000008504
heat shock protein family A member 2
chr10_+_31074251 34.02 ENSRNOT00000007978
SRY box 30
chr1_+_82169620 33.25 ENSRNOT00000088955
ENSRNOT00000068251
proline rich 19
chr7_+_130542202 32.43 ENSRNOT00000079501
ENSRNOT00000045647
acrosin
chr8_-_117353672 31.93 ENSRNOT00000027262
NADH:ubiquinone oxidoreductase complex assembly factor 3
chr20_+_5509059 31.08 ENSRNOT00000065349
kinesin family member C1
chr10_+_74910713 30.83 ENSRNOT00000091619
heat shock transcription factor 5
chr6_+_26517840 30.71 ENSRNOT00000031842
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr5_-_101588598 30.33 ENSRNOT00000082239
PC4 and SFRS1 interacting protein 1
chr1_-_101883744 30.27 ENSRNOT00000028635
synaptogyrin 4
chr10_+_90622992 30.20 ENSRNOT00000032856
meiosis specific with coiled-coil domain
chr8_+_116302513 30.11 ENSRNOT00000039258
zinc finger, MYND-type containing 10
chr19_-_914880 29.86 ENSRNOT00000017127
chemokine-like factor
chr1_+_255040426 28.70 ENSRNOT00000092151
polycomb group ring finger 5
chr5_-_147953093 28.68 ENSRNOT00000075270
KH RNA binding domain containing, signal transduction associated 1
chr7_-_75421874 28.33 ENSRNOT00000012775
poly(A) binding protein, cytoplasmic 1
chr15_-_45927804 27.46 ENSRNOT00000086271
integrator complex subunit 6
chr1_-_65551043 26.97 ENSRNOT00000029996
tripartite motif-containing 28
chr7_+_25832521 26.39 ENSRNOT00000084955
regulatory factor X4
chr5_-_13097341 26.37 ENSRNOT00000061884
RB1-inducible coiled-coil 1
chr11_-_1819094 26.32 ENSRNOT00000000911
similar to 4930453N24Rik protein
chr13_+_94888078 26.05 ENSRNOT00000077995
ENSRNOT00000005647
ENSRNOT00000077345
serologically defined colon cancer antigen 8
chr2_+_206392200 26.02 ENSRNOT00000026631
round spermatid basic protein 1
chr13_-_47916877 25.97 ENSRNOT00000006502
dual specificity tyrosine phosphorylation regulated kinase 3
chr5_+_138470069 25.86 ENSRNOT00000076343
ENSRNOT00000064073
zinc finger, MYND-type containing 12
chr20_-_46666830 25.84 ENSRNOT00000000331
centrosomal protein 57-like 1
chr4_-_77347011 25.55 ENSRNOT00000008149
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr9_+_64898459 25.25 ENSRNOT00000029526
shugoshin 2
chr6_-_23543172 25.05 ENSRNOT00000006073
speedy/RINGO cell cycle regulator family member A
chr2_+_211880262 24.81 ENSRNOT00000038315
solute carrier family 25, member 54
chr2_-_116161998 24.26 ENSRNOT00000012560
G protein-coupled receptor 160
chr1_+_144070754 23.83 ENSRNOT00000079989
SH3 domain-containing GRB2-like 3
chr6_-_107633012 23.61 ENSRNOT00000014018
paraneoplastic Ma antigen 1
chr4_-_165629996 23.57 ENSRNOT00000068185
ENSRNOT00000007427
Y box binding protein 3
chr10_+_89199880 22.17 ENSRNOT00000076865
cyclin N-terminal domain containing 1
chr1_-_225329770 22.17 ENSRNOT00000027459
asparaginase like 1
chr4_-_55527092 22.17 ENSRNOT00000087407
ENSRNOT00000010223
zinc finger protein 800
chr7_-_75422268 22.07 ENSRNOT00000080218
poly(A) binding protein, cytoplasmic 1
chr20_-_32115310 22.01 ENSRNOT00000067883
ENSRNOT00000081916
VPS26 retromer complex component A
chr12_+_38490230 21.23 ENSRNOT00000047861
diablo, IAP-binding mitochondrial protein
chr3_-_93734282 21.21 ENSRNOT00000012428
cell cycle associated protein 1
chr8_+_32165810 21.19 ENSRNOT00000007539
zinc finger and BTB domain containing 44
chr6_-_23542928 21.08 ENSRNOT00000083858
speedy/RINGO cell cycle regulator family member A
chr6_-_128727374 21.01 ENSRNOT00000082152
spectrin repeat containing, nuclear envelope family member 3
chr12_-_31323810 20.70 ENSRNOT00000001247
RAN, member RAS oncogene family
chr18_-_40518988 20.70 ENSRNOT00000004784
fem-1 homolog C
chr9_-_50868238 20.23 ENSRNOT00000015600
testis expressed 30
chrX_-_72034099 19.83 ENSRNOT00000004310
ERCC excision repair 6 like, spindle assembly checkpoint helicase
chr3_-_2770620 19.72 ENSRNOT00000008253
Tnf receptor-associated factor 2
chr1_-_101426852 19.59 ENSRNOT00000028217
RuvB-like AAA ATPase 2
chr3_+_8982122 19.40 ENSRNOT00000024914
protein phosphatase 2 phosphatase activator
chr18_+_51785111 19.35 ENSRNOT00000019351
lamin B1
chr16_+_2379480 19.34 ENSRNOT00000079215
dynein, axonemal, heavy chain 12
chr14_-_84662143 18.93 ENSRNOT00000057529
ENSRNOT00000080078
HORMA domain containing 2
chr3_-_13865843 18.40 ENSRNOT00000025194
Rab9 effector protein with kelch motifs
chr10_+_55138633 18.35 ENSRNOT00000057223
major facilitator superfamily domain containing 6-like
chr3_+_46286712 18.23 ENSRNOT00000085563
membrane associated ring-CH-type finger 7
chr2_-_30664163 17.91 ENSRNOT00000024801
RAD17 checkpoint clamp loader component
chr12_-_22138382 15.85 ENSRNOT00000001899
leucine rich repeats and calponin homology domain containing 4
chr15_+_48327461 15.78 ENSRNOT00000018071
integrator complex subunit 9
chr12_-_24578761 15.37 ENSRNOT00000076209
transducin (beta)-like 2
chr6_-_109103999 15.33 ENSRNOT00000009086
ENSRNOT00000080009
acylphosphatase 1
chr7_+_125937928 15.26 ENSRNOT00000044274
family with sequence similarity 118, member A
chr6_+_78567970 15.24 ENSRNOT00000032743
tetratricopeptide repeat domain 6
chr18_-_63394690 15.17 ENSRNOT00000090078
ENSRNOT00000029431
centrosomal protein 76
chr6_+_8220228 15.04 ENSRNOT00000079279
ENSRNOT00000048656
protein phosphatase, Mg2+/Mn2+ dependent, 1B
chr19_+_24846938 14.94 ENSRNOT00000045974
DExD-box helicase 39A
chr6_-_125853461 14.74 ENSRNOT00000007505
ataxin 3
chr7_-_12640232 14.71 ENSRNOT00000014981
elastase, neutrophil expressed
chr19_+_24747178 14.51 ENSRNOT00000038879
ENSRNOT00000079106
DnaJ heat shock protein family (Hsp40) member B1
chr7_-_12646960 14.48 ENSRNOT00000014687
proteinase 3
chr1_-_53152866 14.05 ENSRNOT00000085501
Fgfr1 oncogene partner
chr12_+_39679688 13.50 ENSRNOT00000050398
family with sequence similarity 216, member A
chr7_+_37812831 13.24 ENSRNOT00000005910
BTG anti-proliferation factor 1
chr1_+_219077771 12.84 ENSRNOT00000022824
choline kinase alpha
chr13_+_51126459 12.61 ENSRNOT00000042046
ENSRNOT00000087240
myogenin
chr19_+_14392423 12.61 ENSRNOT00000018880
target of myb1 membrane trafficking protein
chr1_+_23977688 12.52 ENSRNOT00000014805
TATA-box binding protein like 1
chr11_-_57993548 12.48 ENSRNOT00000002957
nectin cell adhesion molecule 3
chr16_-_21338771 12.42 ENSRNOT00000014265
PBX homeobox 4
chr12_+_40695756 12.14 ENSRNOT00000091375
TRAF type zinc finger domain containing 1
chr1_+_100811755 12.05 ENSRNOT00000074847
nucleoporin 62
chr10_-_31493419 11.98 ENSRNOT00000009211
IL2-inducible T-cell kinase
chr1_+_219078029 11.97 ENSRNOT00000023020
choline kinase alpha
chr1_-_164977633 11.90 ENSRNOT00000029629
ring finger protein 169
chr9_+_17163354 11.85 ENSRNOT00000026049
DNA polymerase eta
chr5_+_143027977 11.77 ENSRNOT00000012702
G protein nucleolar 2
chr16_-_75530500 11.76 ENSRNOT00000018580
ENSRNOT00000086035
defensin RatNP-3 precursor
chr1_-_78851719 11.70 ENSRNOT00000022603
calmodulin 2
chr5_+_169357517 11.67 ENSRNOT00000000079
acyl-CoA thioesterase 7
chr18_-_27424090 11.53 ENSRNOT00000087968
bromodomain containing 8
chr10_+_71278650 11.23 ENSRNOT00000092020
synergin, gamma
chr3_-_2490392 10.87 ENSRNOT00000014993
SS nuclear autoantigen 1
chr13_-_79801368 10.81 ENSRNOT00000075998
ENSRNOT00000084058
SUN domain containing ossification factor
chr4_-_62663200 10.74 ENSRNOT00000040969
CCR4-NOT transcription complex, subunit 4
chr3_-_138462063 10.72 ENSRNOT00000065553
ovo-like zinc finger 2
chr15_+_19690194 10.62 ENSRNOT00000010612
serine/threonine/tyrosine interacting protein
chr13_-_85443727 10.58 ENSRNOT00000090668
ENSRNOT00000076125
uridine-cytidine kinase 2
chr9_+_82345719 10.36 ENSRNOT00000057330
ENSRNOT00000078260
family with sequence similarity 134, member A
chr7_+_64987859 10.00 ENSRNOT00000005694
transmembrane BAX inhibitor motif containing 4
chr7_-_70577147 9.99 ENSRNOT00000008854
methyl-CpG binding domain protein 6
chr1_-_89042176 9.44 ENSRNOT00000080842
lysine methyltransferase 2B
chr8_-_97494834 9.42 ENSRNOT00000080421
mortality factor 4 like 1
chr11_-_4397361 9.09 ENSRNOT00000046370
cell adhesion molecule 2
chr7_+_70580198 9.07 ENSRNOT00000083472
ENSRNOT00000008941
DNA-damage inducible transcript 3
chr5_-_134871775 9.07 ENSRNOT00000015667
fatty-acid amide hydrolase 1-like
chr20_-_13706205 8.99 ENSRNOT00000038623
derlin 3
chr8_+_64573358 8.82 ENSRNOT00000083558
myosin IXA
chr14_+_82356916 8.71 ENSRNOT00000040229
stem-loop binding protein
chr3_+_170380719 8.63 ENSRNOT00000055101
cleavage stimulation factor subunit 1
chr12_+_40695520 8.53 ENSRNOT00000033984
TRAF type zinc finger domain containing 1
chr6_+_51662224 8.31 ENSRNOT00000060006
coiled-coil domain containing 71-like
chr8_-_104790639 8.22 ENSRNOT00000017085
2-phosphoxylose phosphatase 1
chr2_-_189899103 8.13 ENSRNOT00000010455
chromatin target of PRMT1
chr10_+_43446526 8.08 ENSRNOT00000036959
La ribonucleoprotein domain family, member 1
chr4_+_85009350 8.07 ENSRNOT00000072271
zinc and ring finger 2
chr2_+_187668796 7.61 ENSRNOT00000025824
chaperonin containing TCP1 subunit 3
chr13_-_79801561 7.41 ENSRNOT00000075936
SUN domain containing ossification factor
chr1_+_198298138 7.39 ENSRNOT00000039964
HIRA interacting protein 3
chr7_-_75597087 7.27 ENSRNOT00000080676
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr2_-_189899325 7.18 ENSRNOT00000017561
chromatin target of PRMT1
chr4_-_145329878 7.04 ENSRNOT00000011827
transcriptional adaptor 3
chr19_+_22699808 6.75 ENSRNOT00000023169
similar to RIKEN cDNA 4921524J17
chr13_-_79801112 6.59 ENSRNOT00000087323
ENSRNOT00000036483
SUN domain containing ossification factor
chr15_+_32763067 6.56 ENSRNOT00000011998

chr1_-_198577226 6.34 ENSRNOT00000055013
sialophorin
chr14_-_108658371 6.33 ENSRNOT00000008919
poly(A) polymerase gamma
chr7_-_117128798 6.28 ENSRNOT00000045280
scribbled planar cell polarity protein
chr13_+_99136871 6.15 ENSRNOT00000078263
ENSRNOT00000004350
SDE2 telomere maintenance homolog
chr15_-_104168564 5.88 ENSRNOT00000093385
ENSRNOT00000038596
DAZ interacting zinc finger protein 1
chr5_-_165442048 5.80 ENSRNOT00000049822
TAR DNA binding protein
chr1_-_266934303 5.70 ENSRNOT00000036202
calcium homeostasis modulator 3
chr1_+_88182585 5.56 ENSRNOT00000044145
Yip1 interacting factor homolog B, membrane trafficking protein
chr15_+_28074953 5.49 ENSRNOT00000086427
ribonuclease pancreatic beta-type
chr4_+_24612205 5.44 ENSRNOT00000057382
EWS RNA-binding protein 1
chr15_+_52265557 4.98 ENSRNOT00000015969
nudix hydrolase 18
chr10_-_83128297 4.95 ENSRNOT00000082160
lysine acetyltransferase 7
chr1_-_199037267 4.86 ENSRNOT00000078779
coiled-coil domain containing 189
chr11_+_88388378 4.59 ENSRNOT00000029851
immunoglobulin lambda-like polypeptide 1
chr4_+_149957206 4.58 ENSRNOT00000083843
heterogeneous nuclear ribonucleoprotein F
chr18_-_79258570 4.50 ENSRNOT00000022401
galanin receptor 1
chr20_-_28873363 4.23 ENSRNOT00000071064
small nuclear ribonucleoprotein D2-like
chr3_-_161498951 4.05 ENSRNOT00000024214
nuclear receptor coactivator 5
chr1_-_220067123 3.91 ENSRNOT00000071020
ENSRNOT00000072373
RNA binding motif protein 14
chr10_-_89699836 3.72 ENSRNOT00000084311
ets variant 4
chr8_-_64268555 3.62 ENSRNOT00000013581
ENSRNOT00000084758
ariadne RBR E3 ubiquitin protein ligase 1
chr3_-_112676556 3.56 ENSRNOT00000014664
codanin 1
chr7_-_75597276 3.54 ENSRNOT00000035628
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr9_+_94279155 3.44 ENSRNOT00000065805
protease, serine, 56
chr19_+_37127508 3.26 ENSRNOT00000019656
core-binding factor, beta subunit
chr1_-_263845762 3.04 ENSRNOT00000017268
ER lipid raft associated 1
chr3_+_153398130 2.92 ENSRNOT00000068135
ribophorin II
chrX_-_64715823 2.49 ENSRNOT00000076297
ankyrin repeat and SOCS box-containing 12
chr8_-_59313521 2.43 ENSRNOT00000017239
ENSRNOT00000090439
WD repeat domain 61
chr18_+_40586315 2.43 ENSRNOT00000041237
eukaryotic translation initiation factor 1A
chr8_-_118436894 2.28 ENSRNOT00000073395
ATR-interacting protein-like
chr10_+_44271587 2.23 ENSRNOT00000047700
tripartite motif-containing 58
chr2_+_52301798 2.18 ENSRNOT00000091387
poly(A) binding protein interacting protein 1
chr1_-_42741551 2.13 ENSRNOT00000045014

chr5_-_24255606 2.11 ENSRNOT00000037483
pleckstrin homology and FYVE domain containing 2
chr13_-_95943761 2.03 ENSRNOT00000005961
adenylosuccinate synthase
chr8_+_118803075 2.01 ENSRNOT00000087154
SET domain containing 2
chr2_+_188253220 1.95 ENSRNOT00000027629
ASH1 like histone lysine methyltransferase
chr10_-_110182291 1.92 ENSRNOT00000015178
ENSRNOT00000054936
casein kinase 1, delta
chr8_-_117811975 1.78 ENSRNOT00000028055
ATR interacting protein

Network of associatons between targets according to the STRING database.

First level regulatory network of Myb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
26.3 78.9 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
14.8 44.5 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
11.5 57.7 GO:0015793 glycerol transport(GO:0015793)
9.6 28.7 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
9.0 35.9 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
8.5 143.7 GO:0034587 piRNA metabolic process(GO:0034587)
8.4 25.3 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
8.4 50.4 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
8.3 24.8 GO:1903165 response to polycyclic arene(GO:1903165)
8.2 57.5 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
6.7 27.0 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
6.6 26.4 GO:0030242 pexophagy(GO:0030242)
6.6 19.7 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
6.5 19.6 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
5.9 23.6 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
5.6 39.0 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
5.3 26.4 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
5.2 26.0 GO:0035617 stress granule disassembly(GO:0035617)
5.1 182.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
4.9 14.7 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
4.8 19.4 GO:1904009 cellular response to monosodium glutamate(GO:1904009)
4.3 30.2 GO:0007144 female meiosis I(GO:0007144)
4.3 25.5 GO:0035983 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834) response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
4.2 12.6 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
4.1 8.2 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909)
4.0 12.1 GO:1902412 positive regulation of centriole replication(GO:0046601) regulation of mitotic cytokinesis(GO:1902412)
3.9 11.7 GO:0036115 medium-chain fatty-acyl-CoA metabolic process(GO:0036112) fatty-acyl-CoA catabolic process(GO:0036115)
3.8 30.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
3.8 60.4 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
3.7 22.2 GO:0006528 asparagine metabolic process(GO:0006528)
3.6 10.9 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
3.6 50.2 GO:0019985 translesion synthesis(GO:0019985)
3.2 6.3 GO:0001807 regulation of type IV hypersensitivity(GO:0001807)
3.1 12.5 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
3.0 45.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
3.0 20.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
2.9 14.5 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
2.9 71.8 GO:0048240 sperm capacitation(GO:0048240)
2.8 24.8 GO:0015866 ADP transport(GO:0015866)
2.7 10.7 GO:0060214 endocardium formation(GO:0060214)
2.7 21.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
2.6 10.6 GO:0044211 CTP salvage(GO:0044211)
2.6 21.0 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
2.3 41.1 GO:0070986 left/right axis specification(GO:0070986)
2.2 10.8 GO:0090168 Golgi reassembly(GO:0090168)
2.2 19.4 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
2.1 18.9 GO:0045144 meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177)
2.1 18.8 GO:1902414 protein localization to cell junction(GO:1902414)
2.0 85.7 GO:0048255 mRNA stabilization(GO:0048255)
1.9 11.7 GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051343)
1.9 59.0 GO:0006458 'de novo' protein folding(GO:0006458)
1.8 9.1 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
1.8 30.1 GO:0036159 inner dynein arm assembly(GO:0036159)
1.7 5.0 GO:0046066 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
1.7 5.0 GO:0072720 response to dithiothreitol(GO:0072720)
1.6 31.9 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
1.5 15.3 GO:0051096 positive regulation of helicase activity(GO:0051096)
1.5 11.9 GO:0071494 cellular response to UV-C(GO:0071494)
1.5 19.1 GO:0046599 regulation of centriole replication(GO:0046599)
1.5 8.7 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
1.3 103.6 GO:0008542 visual learning(GO:0008542)
1.2 20.9 GO:0043968 histone H2A acetylation(GO:0043968)
1.2 15.9 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
1.2 46.1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
1.2 13.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
1.1 4.5 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
1.1 31.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
1.1 12.0 GO:0001865 NK T cell differentiation(GO:0001865)
1.1 14.7 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
1.0 6.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
1.0 2.0 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
1.0 19.4 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
1.0 22.0 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.9 18.2 GO:0002643 regulation of tolerance induction(GO:0002643)
0.8 2.4 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.8 24.8 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.8 6.9 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) regulation of retrograde protein transport, ER to cytosol(GO:1904152) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.7 22.2 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.7 17.2 GO:0016180 snRNA processing(GO:0016180)
0.7 21.2 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.7 7.0 GO:0090042 tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043)
0.7 29.9 GO:0048246 macrophage chemotaxis(GO:0048246)
0.7 2.0 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.7 2.0 GO:1903699 histone H3-K36 dimethylation(GO:0097676) tarsal gland development(GO:1903699)
0.6 150.9 GO:0007281 germ cell development(GO:0007281)
0.6 11.9 GO:2000780 negative regulation of double-strand break repair(GO:2000780)
0.6 11.8 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.6 44.2 GO:0006405 RNA export from nucleus(GO:0006405)
0.5 14.1 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.5 3.0 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.4 20.7 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.4 26.1 GO:0031023 microtubule organizing center organization(GO:0031023)
0.4 38.2 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.4 23.6 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)
0.4 0.8 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.4 25.8 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.3 1.4 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.3 15.4 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.3 1.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.3 0.8 GO:2000491 regulation of isoprenoid metabolic process(GO:0019747) positive regulation of hepatic stellate cell activation(GO:2000491)
0.2 0.7 GO:0006480 N-terminal protein amino acid methylation(GO:0006480) peptidyl-glycine modification(GO:0018201)
0.2 4.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.2 5.9 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.2 56.2 GO:0007283 spermatogenesis(GO:0007283)
0.2 10.7 GO:0051865 protein autoubiquitination(GO:0051865)
0.2 1.9 GO:0007020 microtubule nucleation(GO:0007020)
0.2 4.1 GO:0000077 DNA damage checkpoint(GO:0000077)
0.2 15.7 GO:1903955 positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 3.3 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 10.0 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.1 4.2 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 4.0 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.1 3.6 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.1 1.0 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.1 16.9 GO:0007018 microtubule-based movement(GO:0007018)
0.1 1.4 GO:1903830 magnesium ion transport(GO:0015693) magnesium ion transmembrane transport(GO:1903830)
0.1 4.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 91.7 GO:0055085 transmembrane transport(GO:0055085)
0.1 1.2 GO:0006378 mRNA polyadenylation(GO:0006378)
0.1 29.4 GO:0016567 protein ubiquitination(GO:0016567)
0.0 0.7 GO:0006379 mRNA cleavage(GO:0006379)
0.0 2.9 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.3 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.0 1.3 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 2.3 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
13.4 40.1 GO:1990423 RZZ complex(GO:1990423)
13.1 78.8 GO:0071547 piP-body(GO:0071547)
10.0 50.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
9.1 100.1 GO:0002177 manchette(GO:0002177)
6.5 32.4 GO:0043159 acrosomal matrix(GO:0043159)
6.4 64.4 GO:0044613 nuclear pore central transport channel(GO:0044613)
5.5 22.0 GO:0030906 retromer, cargo-selective complex(GO:0030906)
5.1 35.9 GO:0036128 CatSper complex(GO:0036128)
4.8 86.9 GO:0033391 chromatoid body(GO:0033391)
3.9 19.7 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
3.7 52.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
3.4 109.4 GO:0034451 centriolar satellite(GO:0034451)
3.3 26.4 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
3.3 19.6 GO:0097255 R2TP complex(GO:0097255)
3.0 9.1 GO:1990622 CHOP-C/EBP complex(GO:0036488) CHOP-ATF3 complex(GO:1990622)
3.0 21.0 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
2.4 19.4 GO:0005638 lamin filament(GO:0005638)
2.1 6.3 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
2.1 60.4 GO:0035371 microtubule plus-end(GO:0035371)
2.1 45.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
1.9 83.8 GO:0000795 synaptonemal complex(GO:0000795)
1.9 21.2 GO:0035631 CD40 receptor complex(GO:0035631)
1.8 25.3 GO:0008278 cohesin complex(GO:0008278)
1.7 91.1 GO:0005844 polysome(GO:0005844)
1.6 9.5 GO:0005672 transcription factor TFIIA complex(GO:0005672)
1.6 31.7 GO:0005680 anaphase-promoting complex(GO:0005680)
1.5 9.0 GO:0005785 signal recognition particle receptor complex(GO:0005785)
1.5 5.8 GO:0005726 perichromatin fibrils(GO:0005726)
1.3 14.7 GO:0042405 nuclear inclusion body(GO:0042405)
1.3 32.8 GO:0035327 transcriptionally active chromatin(GO:0035327)
1.3 11.5 GO:0000812 Swr1 complex(GO:0000812)
1.3 25.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
1.1 4.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
1.1 24.8 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
1.1 8.7 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
1.1 183.9 GO:0031514 motile cilium(GO:0031514)
1.1 28.0 GO:0005719 nuclear euchromatin(GO:0005719)
1.0 17.2 GO:0032039 integrator complex(GO:0032039)
1.0 51.7 GO:0000794 condensed nuclear chromosome(GO:0000794)
1.0 36.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.9 11.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.8 92.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.8 15.3 GO:0000346 transcription export complex(GO:0000346)
0.8 12.4 GO:0001741 XY body(GO:0001741)
0.8 10.0 GO:0010369 chromocenter(GO:0010369)
0.7 5.9 GO:0097539 ciliary transition fiber(GO:0097539)
0.7 9.4 GO:0016580 Sin3 complex(GO:0016580)
0.7 3.6 GO:0097413 Lewy body(GO:0097413)
0.7 19.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.6 10.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.6 31.1 GO:0005871 kinesin complex(GO:0005871)
0.5 7.0 GO:0030914 SAGA complex(GO:0000124) STAGA complex(GO:0030914)
0.5 6.3 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.5 55.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.5 42.0 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.5 11.9 GO:0035861 site of double-strand break(GO:0035861)
0.4 10.8 GO:0042629 mast cell granule(GO:0042629)
0.3 23.8 GO:0031901 early endosome membrane(GO:0031901)
0.3 12.0 GO:0030286 dynein complex(GO:0030286)
0.3 0.8 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 14.6 GO:0016605 PML body(GO:0016605)
0.2 4.2 GO:0005685 U1 snRNP(GO:0005685) U2 snRNP(GO:0005686)
0.2 90.7 GO:0005813 centrosome(GO:0005813)
0.2 10.7 GO:0035097 histone methyltransferase complex(GO:0035097)
0.2 5.4 GO:0015030 Cajal body(GO:0015030)
0.2 2.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 17.9 GO:0000781 chromosome, telomeric region(GO:0000781)
0.2 51.2 GO:0016607 nuclear speck(GO:0016607)
0.1 9.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 45.0 GO:0005635 nuclear envelope(GO:0005635)
0.1 45.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 5.0 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.1 4.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 10.1 GO:0032993 protein-DNA complex(GO:0032993)
0.1 12.6 GO:0005769 early endosome(GO:0005769)
0.1 0.7 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.6 GO:0097546 ciliary base(GO:0097546)
0.0 1.4 GO:0016235 aggresome(GO:0016235)
0.0 9.4 GO:0043235 receptor complex(GO:0043235)
0.0 1.3 GO:0000502 proteasome complex(GO:0000502)
0.0 16.9 GO:0005730 nucleolus(GO:0005730)
0.0 31.1 GO:0005654 nucleoplasm(GO:0005654)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
19.7 78.9 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
14.8 44.5 GO:0004370 glycerol kinase activity(GO:0004370)
10.8 32.4 GO:0004040 amidase activity(GO:0004040)
10.0 160.3 GO:0008143 poly(A) binding(GO:0008143)
9.0 27.0 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
7.8 39.0 GO:0010997 anaphase-promoting complex binding(GO:0010997)
5.0 64.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
5.0 24.8 GO:0004104 choline kinase activity(GO:0004103) cholinesterase activity(GO:0004104)
4.8 142.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
4.4 31.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
4.1 20.7 GO:0061676 importin-alpha family protein binding(GO:0061676)
4.1 57.7 GO:0015250 water channel activity(GO:0015250)
3.4 30.3 GO:0097100 supercoiled DNA binding(GO:0097100)
3.3 19.6 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
3.2 64.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
2.9 11.7 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
2.8 24.8 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
2.6 25.5 GO:0070878 primary miRNA binding(GO:0070878)
2.5 19.7 GO:0046625 sphingolipid binding(GO:0046625)
2.5 14.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
2.1 10.6 GO:0004849 uridine kinase activity(GO:0004849)
2.0 22.2 GO:0008242 omega peptidase activity(GO:0008242)
1.8 17.9 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
1.8 14.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
1.7 83.9 GO:0045182 translation regulator activity(GO:0045182)
1.7 5.0 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
1.6 35.9 GO:0051861 glycolipid binding(GO:0051861)
1.4 94.5 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
1.2 154.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
1.0 19.4 GO:0043274 phospholipase binding(GO:0043274)
0.9 29.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.9 9.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.9 6.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.8 29.9 GO:0008009 chemokine activity(GO:0008009)
0.8 25.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.7 45.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.7 9.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.6 56.7 GO:0051087 chaperone binding(GO:0051087)
0.6 6.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.6 26.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.6 50.4 GO:0003777 microtubule motor activity(GO:0003777)
0.6 4.5 GO:0004966 galanin receptor activity(GO:0004966)
0.5 13.7 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.5 12.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.5 8.7 GO:0036002 pre-mRNA binding(GO:0036002)
0.4 8.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.4 4.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.4 50.6 GO:0030674 protein binding, bridging(GO:0030674)
0.4 59.9 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.4 2.0 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.4 22.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.4 5.0 GO:0003688 DNA replication origin binding(GO:0003688)
0.3 11.4 GO:0031369 translation initiation factor binding(GO:0031369)
0.3 7.0 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.3 2.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.3 12.6 GO:0070888 E-box binding(GO:0070888)
0.2 4.6 GO:0017025 TBP-class protein binding(GO:0017025)
0.2 17.0 GO:0032947 protein complex scaffold(GO:0032947)
0.2 12.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 10.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 0.7 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.2 2.9 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2 0.8 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.2 6.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.2 12.5 GO:0030276 clathrin binding(GO:0030276)
0.2 11.9 GO:0003684 damaged DNA binding(GO:0003684)
0.2 1.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 16.5 GO:0008565 protein transporter activity(GO:0008565)
0.2 8.8 GO:0003774 motor activity(GO:0003774)
0.1 3.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 136.4 GO:0008270 zinc ion binding(GO:0008270)
0.1 1.0 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 3.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 26.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 116.6 GO:0022857 transmembrane transporter activity(GO:0022857)
0.1 42.4 GO:0019901 protein kinase binding(GO:0019901)
0.1 144.6 GO:0003677 DNA binding(GO:0003677)
0.1 21.5 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 3.0 GO:0015485 cholesterol binding(GO:0015485)
0.0 2.0 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.0 15.5 GO:0008289 lipid binding(GO:0008289)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 103.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
1.6 20.7 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
1.1 58.9 PID PLK1 PATHWAY PLK1 signaling events
1.0 44.9 PID ATM PATHWAY ATM pathway
0.9 60.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.6 19.6 PID MYC PATHWAY C-MYC pathway
0.5 14.1 PID BARD1 PATHWAY BARD1 signaling events
0.4 12.6 PID ATR PATHWAY ATR signaling pathway
0.4 6.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.4 33.3 PID CMYB PATHWAY C-MYB transcription factor network
0.3 19.7 PID MTOR 4PATHWAY mTOR signaling pathway
0.3 3.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.2 12.0 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.2 50.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 12.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.2 12.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 30.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
2.6 63.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
2.1 120.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
2.0 31.7 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
1.8 24.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
1.3 19.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
1.1 32.8 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
1.1 11.7 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
1.0 31.1 REACTOME KINESINS Genes involved in Kinesins
1.0 68.1 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.9 60.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.8 8.7 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.7 19.7 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.7 10.8 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.6 6.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.6 19.6 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.6 21.2 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.5 14.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.5 7.6 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.5 8.6 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.4 12.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.4 18.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.4 9.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.4 10.6 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.4 12.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 6.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.2 2.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 12.9 REACTOME DNA REPAIR Genes involved in DNA Repair
0.1 20.9 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.1 1.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 2.9 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.8 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis