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GSE53960: rat RNA-Seq transcriptomic Bodymap
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Results for Myb
Z-value: 1.65
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Transcription factors associated with Myb
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Myb | rn6_v1_chr1_-_16687817_16687817 | 0.17 | 2.2e-03 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr15_-_42751330 Show fit | 103.63 |
ENSRNOT00000066478
|
ADAM metallopeptidase domain 2 |
|
| chr19_+_24545318 Show fit | 90.52 |
ENSRNOT00000005071
|
calmegin |
|
| chr1_+_51619875 Show fit | 81.21 |
ENSRNOT00000023319
|
poly(A) binding protein, cytoplasmic 6 |
|
| chr10_-_56530842 Show fit | 80.07 |
ENSRNOT00000077451
|
|
|
| chr11_-_88038518 Show fit | 79.37 |
ENSRNOT00000051991
|
RIMS binding protein 3 |
|
| chr1_+_102915191 Show fit | 78.85 |
ENSRNOT00000017851
|
lactate dehydrogenase C |
|
| chr6_+_136536736 Show fit | 78.85 |
ENSRNOT00000086594
|
tudor domain containing 9 |
|
| chr10_+_56546710 Show fit | 78.74 |
ENSRNOT00000023003
|
Y box binding protein 2 |
|
| chr2_-_187668677 Show fit | 73.39 |
ENSRNOT00000056898
ENSRNOT00000092563 |
TSSK6 activating co-chaperone |
|
| chr2_-_84531192 Show fit | 71.77 |
ENSRNOT00000065312
ENSRNOT00000090540 |
rhophilin associated tail protein 1-like |
Network of associatons between targets according to the STRING database.
First level regulatory network of Myb
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.1 | 182.3 | GO:0007339 | binding of sperm to zona pellucida(GO:0007339) |
| 0.6 | 150.9 | GO:0007281 | germ cell development(GO:0007281) |
| 8.5 | 143.7 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 1.3 | 103.6 | GO:0008542 | visual learning(GO:0008542) |
| 0.1 | 91.7 | GO:0055085 | transmembrane transport(GO:0055085) |
| 2.0 | 85.7 | GO:0048255 | mRNA stabilization(GO:0048255) |
| 26.3 | 78.9 | GO:0019244 | lactate biosynthetic process from pyruvate(GO:0019244) |
| 2.9 | 71.8 | GO:0048240 | sperm capacitation(GO:0048240) |
| 3.8 | 60.4 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 1.9 | 59.0 | GO:0006458 | 'de novo' protein folding(GO:0006458) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 183.9 | GO:0031514 | motile cilium(GO:0031514) |
| 3.4 | 109.4 | GO:0034451 | centriolar satellite(GO:0034451) |
| 9.1 | 100.1 | GO:0002177 | manchette(GO:0002177) |
| 0.8 | 92.2 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 1.7 | 91.1 | GO:0005844 | polysome(GO:0005844) |
| 0.2 | 90.7 | GO:0005813 | centrosome(GO:0005813) |
| 4.8 | 86.9 | GO:0033391 | chromatoid body(GO:0033391) |
| 1.9 | 83.8 | GO:0000795 | synaptonemal complex(GO:0000795) |
| 13.1 | 78.8 | GO:0071547 | piP-body(GO:0071547) |
| 6.4 | 64.4 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 10.0 | 160.3 | GO:0008143 | poly(A) binding(GO:0008143) |
| 1.2 | 154.0 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.1 | 144.6 | GO:0003677 | DNA binding(GO:0003677) |
| 4.8 | 142.6 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.1 | 136.4 | GO:0008270 | zinc ion binding(GO:0008270) |
| 0.1 | 116.6 | GO:0022857 | transmembrane transporter activity(GO:0022857) |
| 1.4 | 94.5 | GO:0003724 | RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) |
| 1.7 | 83.9 | GO:0045182 | translation regulator activity(GO:0045182) |
| 19.7 | 78.9 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
| 5.0 | 64.8 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.3 | 103.6 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.9 | 60.3 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 1.1 | 58.9 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.2 | 50.4 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 1.0 | 44.9 | PID ATM PATHWAY | ATM pathway |
| 0.4 | 33.3 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 1.6 | 20.7 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.3 | 19.7 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.6 | 19.6 | PID MYC PATHWAY | C-MYC pathway |
| 0.5 | 14.1 | PID BARD1 PATHWAY | BARD1 signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.1 | 120.1 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 1.0 | 68.1 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 2.6 | 63.3 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.9 | 60.0 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 1.1 | 32.8 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 2.0 | 31.7 | REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
| 1.0 | 31.1 | REACTOME KINESINS | Genes involved in Kinesins |
| 6.1 | 30.3 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 1.8 | 24.8 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.6 | 21.2 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |