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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Meox2

Z-value: 1.38

Motif logo

Transcription factors associated with Meox2

Gene Symbol Gene ID Gene Info
ENSRNOG00000006588 mesenchyme homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Meox2rn6_v1_chr6_+_56625650_566256500.451.1e-17Click!

Activity profile of Meox2 motif

Sorted Z-values of Meox2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrM_+_10160 40.99 ENSRNOT00000042928
mitochondrially encoded NADH dehydrogenase 4
chr4_-_129619142 40.86 ENSRNOT00000047453
leiomodin 3
chrM_+_9870 39.03 ENSRNOT00000044582
mitochondrially encoded NADH 4L dehydrogenase
chr2_+_248398917 31.70 ENSRNOT00000045855
guanylate binding protein 1
chr5_+_6373583 31.69 ENSRNOT00000084749

chr10_+_53713938 31.51 ENSRNOT00000004236
ENSRNOT00000086599
ENSRNOT00000085582
myosin heavy chain 2
chr6_-_143065639 28.27 ENSRNOT00000070923

chrM_+_9451 27.52 ENSRNOT00000041241
mitochondrially encoded NADH dehydrogenase 3
chr3_+_16846412 25.85 ENSRNOT00000074266

chrX_-_64715823 22.47 ENSRNOT00000076297
ankyrin repeat and SOCS box-containing 12
chr2_-_211017778 21.92 ENSRNOT00000026883
synaptophysin-like 2
chrM_+_11736 21.83 ENSRNOT00000048767
mitochondrially encoded NADH dehydrogenase 5
chr7_-_107392972 21.82 ENSRNOT00000093425
transmembrane protein 71
chr4_+_51614676 21.31 ENSRNOT00000060494
ankyrin repeat and SOCS box containing 15
chr7_+_116632506 21.16 ENSRNOT00000009811
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
chr9_-_73871888 20.89 ENSRNOT00000017686
acyl-CoA dehydrogenase, long chain
chr2_+_42829413 19.51 ENSRNOT00000065528
actin, beta-like 2
chr10_+_31880918 19.11 ENSRNOT00000059448
T-cell immunoglobulin and mucin domain containing 4
chr4_+_166833320 19.09 ENSRNOT00000031438
taste receptor, type 2, member 120
chr17_+_32973695 18.27 ENSRNOT00000065674
similar to OTTMUSP00000000621
chr2_-_261337163 18.25 ENSRNOT00000030341
TNNI3 interacting kinase
chr4_-_163890801 17.58 ENSRNOT00000081946
immunoreceptor Ly49si1
chr2_-_203680083 16.82 ENSRNOT00000021268
Cd2 molecule
chr19_-_49448072 16.30 ENSRNOT00000014997
C-x(9)-C motif containing 2
chr13_-_113927745 15.85 ENSRNOT00000010910
ENSRNOT00000080616
complement C3d receptor 2
chr6_+_76349362 14.85 ENSRNOT00000043224
aldolase 1 A retrogene 2
chr8_+_100260049 14.70 ENSRNOT00000011090

chr9_-_97151832 14.65 ENSRNOT00000040169
ankyrin repeat and SOCS box-containing 18
chr11_-_45124423 13.85 ENSRNOT00000046383
filamin A interacting protein 1-like
chr4_+_98481520 13.58 ENSRNOT00000078381
ENSRNOT00000048493

chr4_+_109467272 13.49 ENSRNOT00000008212
regenerating family member 3 beta
chr11_-_75144903 13.31 ENSRNOT00000002329
HRAS-like suppressor
chr20_-_45260119 13.15 ENSRNOT00000000718
solute carrier family 16 member 10
chr4_+_162493908 13.10 ENSRNOT00000072064
C-type lectin domain family 2, member D
chr3_+_16571602 12.92 ENSRNOT00000048351
rCG64259-like
chr6_-_21600451 12.90 ENSRNOT00000047674
latent transforming growth factor beta binding protein 1
chr3_-_16441030 12.70 ENSRNOT00000047784

chr7_+_117409576 12.62 ENSRNOT00000017067
cytochrome c-1
chr4_-_163762434 12.43 ENSRNOT00000081854
immunoreceptor Ly49si1
chrX_+_78372257 12.06 ENSRNOT00000046164
G protein-coupled receptor 174
chr1_-_77865870 12.05 ENSRNOT00000017353
EH-domain containing 2
chr17_-_31780120 11.64 ENSRNOT00000058388

chr6_-_141321108 11.25 ENSRNOT00000040556

chr15_+_55461695 11.23 ENSRNOT00000065195
succinate-CoA ligase ADP-forming beta subunit
chr15_-_29548400 11.17 ENSRNOT00000078176

chr4_-_103024841 11.09 ENSRNOT00000090283

chr11_+_85430400 11.08 ENSRNOT00000083198

chr17_-_15519060 11.03 ENSRNOT00000093624
asporin-like 1
chr6_-_139997537 10.89 ENSRNOT00000073207

chrM_+_8599 10.67 ENSRNOT00000049683
mitochondrially encoded cytochrome C oxidase III
chr3_-_16999720 10.62 ENSRNOT00000074382
similar to immunoglobulin kappa-chain VK-1
chr10_-_98388637 10.59 ENSRNOT00000005665
ATP-binding cassette, subfamily A (ABC1), member 8a
chr3_+_16753703 10.23 ENSRNOT00000077741

chr13_-_83202864 10.06 ENSRNOT00000003976
X-C motif chemokine ligand 1
chr6_-_138250089 9.80 ENSRNOT00000048378
immunoglobulin heavy constant mu
chr4_+_64088900 9.75 ENSRNOT00000075341
cholinergic receptor, muscarinic 2
chr3_+_17139670 9.47 ENSRNOT00000073316

chr2_+_41442241 9.40 ENSRNOT00000067546
phosphodiesterase 4D
chr9_-_50762082 9.32 ENSRNOT00000015492
methyltransferase like 21C
chrX_+_77065397 9.13 ENSRNOT00000090007
cytochrome c oxidase subunit 7B
chr15_-_34693034 9.03 ENSRNOT00000083314
mast cell protease 8
chr7_-_29233392 8.88 ENSRNOT00000064241
Spi-C transcription factor
chr3_+_19772056 8.81 ENSRNOT00000044455

chr8_-_87315955 8.77 ENSRNOT00000081437
filamin A interacting protein 1
chr20_+_4020317 8.77 ENSRNOT00000000526
RT1 class II, locus DOb
chr11_-_17684903 8.60 ENSRNOT00000051213
transmembrane protease, serine 15
chr4_-_159399634 8.50 ENSRNOT00000089193
NADH:ubiquinone oxidoreductase subunit A9
chr6_+_108009251 8.44 ENSRNOT00000059073
prostaglandin reductase 2
chr10_+_30038709 8.42 ENSRNOT00000005898
interleukin 12B
chr1_-_14412807 8.40 ENSRNOT00000074583
TNF alpha induced protein 3
chr3_+_97349454 8.25 ENSRNOT00000089524
doublecortin domain containing 5
chr4_+_147275334 8.25 ENSRNOT00000051858
peroxisome proliferator-activated receptor gamma
chr11_+_15081774 8.16 ENSRNOT00000009911
ubiquitin carboxyl-terminal hydrolase 25-like
chrM_+_3904 8.03 ENSRNOT00000040993
mitochondrially encoded NADH dehydrogenase 2
chr7_+_38897278 8.02 ENSRNOT00000006450
epiphycan
chr10_-_98469799 7.97 ENSRNOT00000087502
ENSRNOT00000088646
ATP binding cassette subfamily A member 9
chr6_-_123577695 7.95 ENSRNOT00000006604
forkhead box N3
chrX_+_134979646 7.91 ENSRNOT00000006035
SAM and SH3 domain containing 3
chr4_-_103569159 7.89 ENSRNOT00000084036

chr6_-_143702033 7.79 ENSRNOT00000051410

chr7_+_118685022 7.73 ENSRNOT00000089135
apolipoprotein L, 3
chrX_+_158350347 7.67 ENSRNOT00000066874
protein FAM122B-like
chr3_+_21016266 7.62 ENSRNOT00000010473
olfactory receptor 420
chrX_+_31984612 7.60 ENSRNOT00000005181
BMX non-receptor tyrosine kinase
chr5_+_166870011 7.59 ENSRNOT00000088299
ribosomal protein S2
chr7_-_18793289 7.48 ENSRNOT00000036375

chrX_+_83678339 7.37 ENSRNOT00000005997
apolipoprotein O-like
chrM_+_7919 7.27 ENSRNOT00000046108
mitochondrially encoded ATP synthase 6
chr7_-_12432130 7.13 ENSRNOT00000077301
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr4_+_102351036 7.12 ENSRNOT00000079277

chr10_-_34242985 7.07 ENSRNOT00000046438
similar to novel protein
chr3_-_98092131 7.02 ENSRNOT00000006512
follicle stimulating hormone beta subunit
chr8_+_42322813 7.01 ENSRNOT00000040431
olfactory receptor 1241
chr13_+_51229890 6.99 ENSRNOT00000060669
cytochrome b5 reductase 1
chr13_-_91776397 6.98 ENSRNOT00000073147
mucosal pentraxin 1
chrX_+_121612952 6.95 ENSRNOT00000022122

chr4_-_167202106 6.79 ENSRNOT00000038581
taste receptor, type 2, member 140
chr6_-_142676432 6.66 ENSRNOT00000074947

chr3_-_74545241 6.60 ENSRNOT00000090836
olfactory receptor 531
chr1_-_90149991 6.53 ENSRNOT00000076987
similar to RIKEN cDNA 4931406P16
chr3_+_44025300 6.51 ENSRNOT00000006319
polypeptide N-acetylgalactosaminyltransferase 5
chrM_+_7758 6.51 ENSRNOT00000046201
mitochondrially encoded ATP synthase 8
chr18_-_74059533 6.50 ENSRNOT00000038767
similar to hypothetical protein
chr13_-_37697569 6.46 ENSRNOT00000045263
similar to NADH-ubiquinone oxidoreductase B9 subunit (Complex I-B9) (CI-B9)
chr4_-_167180656 6.43 ENSRNOT00000049487
taste receptor, type 2, member 103
chr13_+_92146586 6.34 ENSRNOT00000004659
olfactory receptor 1588
chr8_-_109621408 6.30 ENSRNOT00000087398
protein phosphatase 2, regulatory subunit B'', alpha
chr14_+_108826831 6.26 ENSRNOT00000083146
ENSRNOT00000009421
B-cell CLL/lymphoma 11A
chr17_+_36451058 6.19 ENSRNOT00000071408
CDK5 regulatory subunit associated protein 1-like 1
chr17_-_43640387 6.18 ENSRNOT00000087731
histone cluster 1 H1 family member c
chr6_+_122254841 6.14 ENSRNOT00000005055
G-protein coupled receptor 65
chr6_-_139102378 6.13 ENSRNOT00000086423

chr15_-_35113678 6.10 ENSRNOT00000059677
cathepsin G
chr12_-_19439977 6.08 ENSRNOT00000060035
neurexophilin and PC-esterase domain family, member 5
chr7_-_3707226 6.05 ENSRNOT00000064380
olfactory receptor 879
chr1_-_173180745 6.04 ENSRNOT00000043904
olfactory receptor 203
chr1_+_228142778 6.02 ENSRNOT00000028517
mitochondrial ribosomal protein L16
chr5_+_16845631 5.97 ENSRNOT00000047889
coiled-coil-helix-coiled-coil-helix domain containing 7
chr3_+_11763706 5.89 ENSRNOT00000078366
SH2 domain containing 3C
chr1_-_242152834 5.86 ENSRNOT00000071614
ENSRNOT00000020412
frataxin
chr3_-_94808861 5.85 ENSRNOT00000038464
proline rich and Gla domain 4
chr17_-_31916553 5.79 ENSRNOT00000074220
uncharacterized LOC100911032
chr3_+_55461420 5.77 ENSRNOT00000073549
glucose-6-phosphatase catalytic subunit 2
chr17_-_54808483 5.71 ENSRNOT00000075683

chr4_+_102290338 5.71 ENSRNOT00000011067

chr10_+_60496864 5.60 ENSRNOT00000081152
olfactory receptor 390
chr15_+_31948035 5.60 ENSRNOT00000071627

chr11_-_32088002 5.58 ENSRNOT00000002732
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr2_-_14701903 5.57 ENSRNOT00000051895
cytochrome c oxidase subunit 7C
chr4_-_164051812 5.51 ENSRNOT00000085719

chr11_-_62067655 5.46 ENSRNOT00000093382
zinc finger and BTB domain containing 20
chr6_-_72805848 5.44 ENSRNOT00000009040
G protein-coupled receptor 33
chr4_-_157154120 5.41 ENSRNOT00000056058
complement C1s
chr13_+_91954138 5.35 ENSRNOT00000074608
ENSRNOT00000037655
absent in melanoma 2
chr4_-_170912629 5.26 ENSRNOT00000055691
endoplasmic reticulum protein 27
chr17_-_70548071 5.26 ENSRNOT00000073144
interleukin 2 receptor subunit alpha
chr6_-_143206772 5.24 ENSRNOT00000073713

chr3_+_18970574 5.24 ENSRNOT00000088394

chr3_-_73510015 5.18 ENSRNOT00000072248
olfactory receptor 483
chr4_+_1459363 5.15 ENSRNOT00000082919
olfactory receptor 1234
chr2_-_170301348 5.07 ENSRNOT00000088131
sucrase-isomaltase
chr7_-_74735650 5.07 ENSRNOT00000014407
cytochrome c oxidase subunit 6C
chr16_+_54358471 5.05 ENSRNOT00000047314
microtubule associated tumor suppressor 1
chr19_+_3325893 5.02 ENSRNOT00000048879
similar to Ig variable region, light chain
chr4_-_69211671 5.01 ENSRNOT00000017852
preprotrypsinogen IV
chr10_-_87195075 5.00 ENSRNOT00000014851
keratin 24
chr15_+_30621374 4.98 ENSRNOT00000090632

chr4_-_164174725 4.97 ENSRNOT00000080754

chr11_+_76833761 4.97 ENSRNOT00000042650
urotensin 2B
chr1_-_211265161 4.93 ENSRNOT00000080041
ENSRNOT00000023477
BCL2 interacting protein 3
chr4_+_1671269 4.88 ENSRNOT00000071452
olfactory receptor 1251
chr5_+_121952977 4.87 ENSRNOT00000008278
phosphodiesterase 4B
chr15_-_18521161 4.85 ENSRNOT00000051556
LRRGT00055
chr6_-_142299996 4.79 ENSRNOT00000086580
immunoglobulin heavy variable V8-2
chr15_-_12262164 4.79 ENSRNOT00000008798
olfactory receptor 1606
chr8_+_117117430 4.77 ENSRNOT00000073247
glutathione peroxidase 1
chr3_+_17180411 4.73 ENSRNOT00000058260

chr17_-_81002838 4.69 ENSRNOT00000089807
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr15_+_29096865 4.68 ENSRNOT00000077709

chr3_-_74597393 4.68 ENSRNOT00000013201
olfactory receptor 536
chr11_-_43022565 4.60 ENSRNOT00000002285
ribosomal oxygenase 2
chr15_-_36302945 4.60 ENSRNOT00000075675
olfactory receptor 144-like
chr2_+_233909142 4.59 ENSRNOT00000073197
Dcm5 protein
chr9_+_98279022 4.56 ENSRNOT00000038536
RNA binding motif protein 44
chr1_-_171060011 4.48 ENSRNOT00000042829
olfactory receptor 226
chr1_+_63333283 4.48 ENSRNOT00000086294
vomeronasal 1 receptor 30
chr8_+_133029625 4.41 ENSRNOT00000008809
C-C motif chemokine receptor 3
chr10_-_87521514 4.39 ENSRNOT00000084668
ENSRNOT00000071705
keratin associated protein 2-4-like
chr3_+_103248396 4.37 ENSRNOT00000043710
olfactory receptor 4F15-like
chr1_-_172395872 4.34 ENSRNOT00000055174
olfactory receptor 252
chr3_-_158920794 4.30 ENSRNOT00000074921
olfactory receptor 1252
chr8_-_19180021 4.28 ENSRNOT00000035560
olfactory receptor 7G1-like
chr15_+_31469953 4.27 ENSRNOT00000077849

chr6_-_142880382 4.24 ENSRNOT00000074706
ENSRNOT00000072861

chr1_-_227932603 4.24 ENSRNOT00000033795
membrane spanning 4-domains A6A
chr4_+_61924013 4.23 ENSRNOT00000090717
bisphosphoglycerate mutase
chr3_+_75390030 4.21 ENSRNOT00000037577
olfactory receptor 559
chr18_-_31749647 4.20 ENSRNOT00000044287
nuclear receptor subfamily 3, group C, member 1
chr9_-_23493081 4.12 ENSRNOT00000072144
Rh-associated glycoprotein
chr2_+_195684210 4.11 ENSRNOT00000028316
mitochondrial ribosomal protein L9
chr4_+_148476943 4.10 ENSRNOT00000017689
olfactory receptor 823
chr3_-_74607059 4.07 ENSRNOT00000047002
olfactory receptor 537
chr1_-_149770781 4.05 ENSRNOT00000082185
olfactory receptor 16
chr4_+_106289816 4.05 ENSRNOT00000040075

chr4_+_1658278 4.01 ENSRNOT00000073845
olfactory receptor 1250
chr4_+_87943152 3.96 ENSRNOT00000080536
vomeronasal 1 receptor 78
chr14_+_82769642 3.96 ENSRNOT00000065393
C-terminal binding protein 1
chr10_-_87564327 3.96 ENSRNOT00000064760
ENSRNOT00000068237
similar to keratin associated protein 4-7
chr3_-_76187045 3.91 ENSRNOT00000075650
similar to olfactory receptor 73
chr14_-_44375804 3.91 ENSRNOT00000042825
ribosomal protein P2-like
chr1_+_213636093 3.91 ENSRNOT00000019642
proteasome 26S subunit, non-ATPase 13
chr10_-_102200596 3.90 ENSRNOT00000081519
family with sequence similarity 104, member A
chr14_+_62609484 3.87 ENSRNOT00000003017
GUF1 homolog, GTPase
chr2_+_46066780 3.86 ENSRNOT00000073226
olfactory receptor 8B8-like
chr6_+_138432550 3.84 ENSRNOT00000056829
a disintegrin and metallopeptidase domain 6
chr3_-_103265059 3.84 ENSRNOT00000073965
putative olfactory receptor GPCRLTM7
chr4_+_1363724 3.83 ENSRNOT00000072782
olfactory receptor 143-like
chr3_+_19366370 3.81 ENSRNOT00000086557

chr3_+_77047466 3.78 ENSRNOT00000089424
olfactory receptor 648
chr1_+_229849892 3.77 ENSRNOT00000072886
olfactory receptor 346

Network of associatons between targets according to the STRING database.

First level regulatory network of Meox2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.1 21.2 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
7.0 20.9 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
5.3 31.7 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
5.1 40.9 GO:0051694 pointed-end actin filament capping(GO:0051694)
4.6 18.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
4.2 8.4 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
4.0 12.0 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
3.4 13.5 GO:1903576 response to L-arginine(GO:1903576)
3.4 10.1 GO:0071663 immunoglobulin production in mucosal tissue(GO:0002426) T-helper 1 cell activation(GO:0035711) granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663) regulation of thymocyte migration(GO:2000410) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
3.1 9.4 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
2.9 8.8 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
2.8 11.2 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
2.7 8.2 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
2.6 13.2 GO:0015801 aromatic amino acid transport(GO:0015801)
2.4 31.5 GO:0001778 plasma membrane repair(GO:0001778)
2.1 49.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
2.1 8.4 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
2.1 6.3 GO:0090247 cell motility involved in somitogenic axis elongation(GO:0090247) regulation of cell motility involved in somitogenic axis elongation(GO:0090249)
2.1 6.3 GO:1903860 negative regulation of dendrite extension(GO:1903860)
2.1 6.2 GO:0035600 tRNA methylthiolation(GO:0035600)
2.0 6.1 GO:0070946 neutrophil mediated killing of gram-positive bacterium(GO:0070946)
2.0 5.9 GO:0018283 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283) proprioception(GO:0019230)
2.0 9.8 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
1.9 28.3 GO:0009642 response to light intensity(GO:0009642)
1.7 16.8 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
1.6 4.9 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
1.6 4.8 GO:0009609 response to symbiotic bacterium(GO:0009609)
1.6 62.1 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
1.3 5.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
1.2 4.9 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
1.2 3.6 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
1.2 3.5 GO:0045399 positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
1.1 13.3 GO:0046485 ether lipid metabolic process(GO:0046485)
1.1 3.3 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
1.0 10.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
1.0 4.0 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
1.0 18.3 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.9 4.7 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.9 6.5 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.9 12.9 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.8 20.9 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.8 0.8 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725)
0.8 6.2 GO:0016584 nucleosome positioning(GO:0016584)
0.8 5.4 GO:0070269 pyroptosis(GO:0070269)
0.7 4.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.7 7.6 GO:0001865 NK T cell differentiation(GO:0001865)
0.6 6.8 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.6 7.4 GO:0042407 cristae formation(GO:0042407)
0.6 3.1 GO:0010958 regulation of amino acid import(GO:0010958) glycine import(GO:0036233)
0.6 7.9 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.6 8.5 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.6 4.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.5 1.6 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.5 2.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.5 2.6 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.5 3.6 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.5 10.1 GO:0009750 response to fructose(GO:0009750)
0.5 4.6 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.5 1.4 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.5 39.2 GO:0050909 sensory perception of taste(GO:0050909)
0.5 2.7 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.5 2.7 GO:0051660 establishment of centrosome localization(GO:0051660)
0.4 7.6 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.4 21.9 GO:0021762 substantia nigra development(GO:0021762)
0.4 1.6 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.4 3.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.3 4.2 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.3 8.0 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.3 1.6 GO:0035617 stress granule disassembly(GO:0035617)
0.3 3.7 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.3 3.0 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.3 3.6 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.3 4.4 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.3 6.1 GO:0010447 response to acidic pH(GO:0010447)
0.3 4.1 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.3 336.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.2 12.1 GO:0043029 T cell homeostasis(GO:0043029)
0.2 3.9 GO:0043248 proteasome assembly(GO:0043248)
0.2 2.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 8.4 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.2 8.2 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.2 0.9 GO:0052422 modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422) regulation of exo-alpha-sialidase activity(GO:1903015)
0.2 2.7 GO:0006337 nucleosome disassembly(GO:0006337)
0.2 11.0 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.2 2.8 GO:0042976 activation of Janus kinase activity(GO:0042976)
0.2 2.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.2 3.4 GO:0019236 response to pheromone(GO:0019236)
0.2 2.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.2 0.8 GO:0032960 regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.2 5.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 5.1 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.2 1.0 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.2 1.9 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.2 1.1 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.2 1.9 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.2 1.1 GO:0046687 response to chromate(GO:0046687)
0.1 1.2 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.1 11.4 GO:0006096 glycolytic process(GO:0006096)
0.1 10.3 GO:0042100 B cell proliferation(GO:0042100)
0.1 7.0 GO:0016126 sterol biosynthetic process(GO:0016126)
0.1 6.0 GO:0032543 mitochondrial translation(GO:0032543)
0.1 0.9 GO:1904869 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.1 4.4 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 5.0 GO:0045103 intermediate filament-based process(GO:0045103)
0.1 4.9 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 0.4 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.1 1.1 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.1 1.5 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 3.1 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 22.2 GO:0006869 lipid transport(GO:0006869)
0.1 0.8 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.1 1.1 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.1 1.1 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 45.6 GO:0016567 protein ubiquitination(GO:0016567)
0.1 2.7 GO:0032570 response to progesterone(GO:0032570)
0.1 3.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.9 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 7.8 GO:0007254 JNK cascade(GO:0007254)
0.0 3.7 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.0 1.0 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.7 GO:2000772 regulation of cellular senescence(GO:2000772)
0.0 0.8 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 2.2 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.5 GO:0097186 amelogenesis(GO:0097186)
0.0 1.6 GO:1903955 positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.4 GO:0032098 regulation of appetite(GO:0032098)
0.0 1.9 GO:0050680 negative regulation of epithelial cell proliferation(GO:0050680)
0.0 0.8 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 1.2 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 3.4 GO:0016485 protein processing(GO:0016485)
0.0 0.8 GO:0007292 female gamete generation(GO:0007292)
0.0 0.2 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 1.1 GO:0008585 female gonad development(GO:0008585)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
7.9 31.7 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
3.5 31.5 GO:0005826 actomyosin contractile ring(GO:0005826)
3.0 152.4 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
1.6 9.8 GO:0032280 symmetric synapse(GO:0032280)
1.3 13.3 GO:0005641 nuclear envelope lumen(GO:0005641)
1.3 19.4 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
1.2 21.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
1.2 12.9 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
1.2 19.8 GO:0045277 respiratory chain complex IV(GO:0045277)
1.1 5.4 GO:0097169 AIM2 inflammasome complex(GO:0097169)
1.1 7.4 GO:0061617 MICOS complex(GO:0061617)
1.0 4.8 GO:0097413 Lewy body(GO:0097413)
0.9 21.9 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.9 7.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.8 8.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.6 33.3 GO:0031672 A band(GO:0031672)
0.6 1.8 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.6 16.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.5 8.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.4 13.5 GO:0042588 zymogen granule(GO:0042588)
0.4 3.9 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.4 1.6 GO:0097149 centralspindlin complex(GO:0097149)
0.2 4.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 6.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 12.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 12.4 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 2.7 GO:0097539 ciliary transition fiber(GO:0097539)
0.2 2.7 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 4.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.2 6.8 GO:0046930 pore complex(GO:0046930)
0.2 6.2 GO:0005719 nuclear euchromatin(GO:0005719)
0.2 3.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 8.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 3.6 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 11.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 9.4 GO:0045095 keratin filament(GO:0045095)
0.1 2.7 GO:0030057 desmosome(GO:0030057)
0.1 4.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 7.6 GO:0032587 ruffle membrane(GO:0032587)
0.1 1.1 GO:0000800 lateral element(GO:0000800)
0.1 7.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 0.9 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 3.3 GO:0030286 dynein complex(GO:0030286)
0.1 0.9 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 18.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 5.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 6.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 1.0 GO:0031082 BLOC complex(GO:0031082)
0.1 15.9 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 4.1 GO:0000786 nucleosome(GO:0000786)
0.0 1.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 8.5 GO:0043209 myelin sheath(GO:0043209)
0.0 14.7 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 3.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 3.3 GO:0005923 bicellular tight junction(GO:0005923)
0.0 2.9 GO:0005802 trans-Golgi network(GO:0005802)
0.0 2.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 36.0 GO:0005739 mitochondrion(GO:0005739)
0.0 2.7 GO:0043204 perikaryon(GO:0043204)
0.0 135.3 GO:0016021 integral component of membrane(GO:0016021)
0.0 3.1 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.6 GO:0005840 ribosome(GO:0005840)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.9 31.7 GO:0019002 GMP binding(GO:0019002)
7.7 23.0 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
5.2 145.9 GO:0003954 NADH dehydrogenase activity(GO:0003954)
3.7 11.2 GO:0004774 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775)
3.5 21.2 GO:0035473 lipase binding(GO:0035473)
3.3 9.8 GO:1990763 arrestin family protein binding(GO:1990763)
3.0 18.3 GO:0031013 troponin I binding(GO:0031013)
2.8 8.4 GO:0047522 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
2.7 40.9 GO:0005523 tropomyosin binding(GO:0005523)
2.7 16.2 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
2.4 26.1 GO:0004875 complement receptor activity(GO:0004875)
2.2 6.7 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
2.1 14.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
2.1 6.2 GO:0050497 methylthiotransferase activity(GO:0035596) transferase activity, transferring alkylthio groups(GO:0050497)
1.8 5.3 GO:0004911 interleukin-2 receptor activity(GO:0004911)
1.4 8.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
1.2 8.2 GO:0050692 DBD domain binding(GO:0050692)
1.2 7.0 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
1.2 5.8 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
1.1 1.1 GO:0002134 UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
1.1 4.2 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
1.0 5.9 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.9 4.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.9 2.7 GO:0031770 growth hormone-releasing hormone receptor binding(GO:0031770)
0.9 9.4 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.8 12.1 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.7 3.6 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.7 19.8 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.6 12.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.6 6.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.6 3.5 GO:0019767 IgE receptor activity(GO:0019767)
0.6 3.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.5 1.6 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.5 2.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.5 4.1 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.5 197.3 GO:0005549 odorant binding(GO:0005549)
0.5 2.8 GO:0005148 prolactin receptor binding(GO:0005148)
0.5 4.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.5 6.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.4 12.9 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.4 4.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.4 4.2 GO:1990239 steroid hormone binding(GO:1990239)
0.4 8.8 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.4 12.6 GO:0009055 electron carrier activity(GO:0009055)
0.4 3.7 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.4 1.8 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.3 6.8 GO:0015288 porin activity(GO:0015288)
0.3 9.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.3 7.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.3 5.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 16.8 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.2 0.8 GO:0033149 FFAT motif binding(GO:0033149)
0.2 4.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 4.7 GO:0008373 sialyltransferase activity(GO:0008373)
0.2 2.2 GO:0019864 IgG binding(GO:0019864)
0.2 2.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 6.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 2.7 GO:0045295 gamma-catenin binding(GO:0045295)
0.2 3.0 GO:0001594 trace-amine receptor activity(GO:0001594)
0.2 0.9 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.2 15.9 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.2 2.0 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 9.5 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.2 140.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.2 7.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 10.3 GO:0019843 rRNA binding(GO:0019843)
0.1 1.9 GO:0008527 taste receptor activity(GO:0008527)
0.1 13.5 GO:0019838 growth factor binding(GO:0019838)
0.1 1.6 GO:0008061 chitin binding(GO:0008061)
0.1 7.2 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.1 15.8 GO:0005179 hormone activity(GO:0005179)
0.1 1.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 20.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 3.6 GO:0004180 carboxypeptidase activity(GO:0004180)
0.1 5.0 GO:0019955 cytokine binding(GO:0019955)
0.1 0.4 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 11.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.9 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 3.9 GO:0043022 ribosome binding(GO:0043022)
0.1 1.1 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 14.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 6.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 5.5 GO:0004620 phospholipase activity(GO:0004620)
0.1 4.0 GO:0051287 NAD binding(GO:0051287)
0.0 1.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 3.3 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 14.6 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 6.7 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 5.5 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.1 GO:0000182 rDNA binding(GO:0000182)
0.0 1.1 GO:0002020 protease binding(GO:0002020)
0.0 3.0 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 26.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.3 8.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.3 8.4 PID IL27 PATHWAY IL27-mediated signaling events
0.2 13.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2 13.1 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.2 7.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 5.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 11.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 3.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 1.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 4.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 4.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 1.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 2.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.9 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 4.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 9.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 4.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 20.9 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
1.1 6.7 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.8 11.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.8 12.7 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.7 7.0 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.6 40.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.6 6.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.5 30.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.5 5.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.5 4.8 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.5 14.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.4 8.0 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.4 3.3 REACTOME DEFENSINS Genes involved in Defensins
0.3 14.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.3 5.4 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.3 4.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.2 8.4 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.2 2.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 44.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.2 12.4 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.2 12.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 5.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.2 6.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 5.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 5.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 6.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 4.1 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 5.8 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 3.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 2.1 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 4.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 2.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 2.7 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 1.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.8 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 3.3 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 2.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.9 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism