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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Meox1

Z-value: 0.66

Motif logo

Transcription factors associated with Meox1

Gene Symbol Gene ID Gene Info
ENSRNOG00000020803 mesenchyme homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Meox1rn6_v1_chr10_-_89816491_89816491-0.122.6e-02Click!

Activity profile of Meox1 motif

Sorted Z-values of Meox1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_95501778 29.60 ENSRNOT00000086805
secreted phosphoprotein 2
chr5_-_126911520 22.06 ENSRNOT00000091521
deiodinase, iodothyronine, type I
chr17_-_43537293 19.01 ENSRNOT00000091749
solute carrier family 17 member 3
chr18_-_6781841 18.71 ENSRNOT00000077606
ENSRNOT00000048109
aquaporin 4
chr14_+_22517774 16.71 ENSRNOT00000047655
UDP-glucuronosyltransferase 2 family, member 37
chr5_-_133959447 14.89 ENSRNOT00000011985
cytochrome P450, family 4, subfamily x, polypeptide 1
chr8_-_78233430 14.44 ENSRNOT00000083220
cingulin-like 1
chr20_+_40769586 14.41 ENSRNOT00000001079
fatty acid binding protein 7
chr12_+_47179664 13.81 ENSRNOT00000001551
calcium binding protein 1
chr14_+_22375955 13.42 ENSRNOT00000063915
ENSRNOT00000034784
UDP-glucuronosyltransferase 2 family, member 37
chr10_-_47666921 12.81 ENSRNOT00000086579
solute carrier family 47 member 1
chr3_+_48096954 12.66 ENSRNOT00000068238
ENSRNOT00000064344
ENSRNOT00000044638
solute carrier family 4 member 10
chr7_-_76294663 11.85 ENSRNOT00000064513
neurocalcin delta
chr4_-_55011415 11.59 ENSRNOT00000056996
glutamate metabotropic receptor 8
chr14_-_64476796 11.56 ENSRNOT00000029104
glucosidase, beta, acid 3
chr7_-_76488216 11.41 ENSRNOT00000080024
neurocalcin delta
chr1_-_67065797 11.25 ENSRNOT00000048152
vomeronasal 1 receptor 46
chrX_+_5825711 11.07 ENSRNOT00000037360
EF-hand domain containing 2
chr1_+_217345545 10.90 ENSRNOT00000071741
SH3 and multiple ankyrin repeat domains 2
chr8_-_82533689 10.52 ENSRNOT00000014124
tropomodulin 2
chr1_+_248428099 10.35 ENSRNOT00000050984
mannose binding lectin 2
chr1_-_189182306 9.59 ENSRNOT00000021249
glycoprotein 2
chr17_+_8489266 9.46 ENSRNOT00000016252
leukocyte cell-derived chemotaxin 2
chr11_+_57207656 8.79 ENSRNOT00000038207
ENSRNOT00000085754
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr8_+_33239139 8.60 ENSRNOT00000011589
Rho GTPase activating protein 32
chr7_+_6644643 8.57 ENSRNOT00000051670
olfactory receptor 962
chr1_+_87224677 8.35 ENSRNOT00000028070
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chrX_-_69218526 8.31 ENSRNOT00000092321
ENSRNOT00000074071
ENSRNOT00000092571
praja ring finger ubiquitin ligase 1
chr1_+_59156251 8.20 ENSRNOT00000017442
limb and CNS expressed 1
chr18_-_24735349 8.19 ENSRNOT00000036537
G protein-coupled receptor 17
chr3_+_63510293 8.19 ENSRNOT00000058093
deafness, autosomal recessive 59
chr20_-_10013190 8.09 ENSRNOT00000084726
ENSRNOT00000089112
radial spoke head 1 homolog
chr1_-_104024682 7.79 ENSRNOT00000056081
MAS-related GPR, member X1
chr2_-_236480502 7.48 ENSRNOT00000015020
sphingomyelin synthase 2
chr2_+_69415057 7.35 ENSRNOT00000013152
cadherin 10
chr1_+_88955135 7.22 ENSRNOT00000083550
proline dehydrogenase 2
chr2_+_22950018 7.16 ENSRNOT00000071804
homer scaffolding protein 1
chrX_+_84064427 6.94 ENSRNOT00000046364
zinc finger protein 711
chr8_-_7426611 6.84 ENSRNOT00000031492
Rho GTPase activating protein 42
chr2_-_40386669 6.83 ENSRNOT00000014074
ELOVL fatty acid elongase 7
chr1_+_219833299 6.83 ENSRNOT00000087432
pyruvate carboxylase
chr20_-_10013559 6.69 ENSRNOT00000091623
radial spoke head 1 homolog
chr11_+_44072043 6.53 ENSRNOT00000033716
similar to CG4349-PA
chrX_+_6273733 6.38 ENSRNOT00000074275
NDP, norrin cystine knot growth factor
chr5_-_173233188 6.30 ENSRNOT00000055343
transmembrane protein 88B
chr6_+_60566196 5.93 ENSRNOT00000006709
ENSRNOT00000075193
dedicator of cytokinesis 4
chr16_+_74865516 5.84 ENSRNOT00000058072
ATPase copper transporting beta
chr18_-_67224566 5.66 ENSRNOT00000064947
DCC netrin 1 receptor
chr17_+_11683862 5.39 ENSRNOT00000024766
msh homeobox 2
chr2_+_187162017 5.35 ENSRNOT00000080693
insulin receptor-related receptor
chr7_-_101138373 5.35 ENSRNOT00000043257
Ab1-152
chr16_-_10802512 5.32 ENSRNOT00000079554
bone morphogenetic protein receptor type 1A
chr9_+_98438439 5.15 ENSRNOT00000027220
selenocysteine lyase
chr1_+_48077033 5.01 ENSRNOT00000020100
MAS1 proto-oncogene, G protein-coupled receptor
chr2_-_18531210 4.97 ENSRNOT00000088313
versican
chr4_-_62860446 4.91 ENSRNOT00000015752
family with sequence similarity 180, member A
chr7_-_140356209 4.86 ENSRNOT00000077856
Rho family GTPase 1
chr12_-_52658275 4.85 ENSRNOT00000041981
zinc finger protein 605
chr7_-_101138860 4.73 ENSRNOT00000077137

chr2_-_158133861 4.59 ENSRNOT00000090700
ventricular zone expressed PH domain-containing 1
chr5_-_161981441 4.46 ENSRNOT00000020316
podoplanin
chr5_-_136965191 4.30 ENSRNOT00000056842
ST3 beta-galactoside alpha-2,3-sialyltransferase 3
chr3_+_123106694 4.21 ENSRNOT00000028829
oxytocin/neurophysin 1 prepropeptide
chr18_+_17043903 4.19 ENSRNOT00000068139
formin homology 2 domain containing 3
chr4_-_67301102 4.19 ENSRNOT00000034549
DENN domain containing 2A
chr4_+_115416580 4.18 ENSRNOT00000018303
ATPase H+ transporting V1 subunit B1
chr7_-_52404774 4.13 ENSRNOT00000082100
neuron navigator 3
chr5_+_78384444 4.01 ENSRNOT00000034978
similar to hypothetical protein 4933430I17
chr7_+_380741 3.99 ENSRNOT00000091013
nidogen-2-like
chr12_+_18679789 3.99 ENSRNOT00000001863
cytochrome P450, family 3, subfamily a, polypeptide 9
chr9_-_44419998 3.86 ENSRNOT00000091397
ENSRNOT00000083747
testis specific 10
chr10_+_109665682 3.83 ENSRNOT00000054963
solute carrier family 25 member 10
chr19_-_24614019 3.82 ENSRNOT00000005124
short coiled-coil protein
chr9_+_84203072 3.77 ENSRNOT00000018882
sphingosine-1-phosphate phosphatase 2
chr7_-_92996025 3.76 ENSRNOT00000076327
sterile alpha motif domain containing 12
chr3_-_26056818 3.76 ENSRNOT00000044209
LDL receptor related protein 1B
chr1_+_69841998 3.72 ENSRNOT00000072231
zinc finger protein 773, pseudogene 1
chr1_+_28454966 3.63 ENSRNOT00000078841
ENSRNOT00000030327
tumor protein D52-like 1
chr6_-_3355339 3.63 ENSRNOT00000084602
mitogen-activated protein kinase kinase kinase kinase 3
chr1_+_185863043 3.57 ENSRNOT00000079072
SRY box 6
chr8_-_39551700 3.56 ENSRNOT00000091894
ENSRNOT00000076025
PBX/knotted 1 homeobox 2
chrX_+_45965301 3.51 ENSRNOT00000005141
family with sequence similarity 47, member A
chr18_+_63203063 3.48 ENSRNOT00000024144
PRELI domain containing 3A
chr18_+_4084228 3.46 ENSRNOT00000071392
calcium binding tyrosine phosphorylation regulated
chr20_+_3830164 3.45 ENSRNOT00000045533
ENSRNOT00000084117
collagen type XI alpha 2 chain
chr17_+_87274944 3.41 ENSRNOT00000073718
enhancer trap locus 4
chr7_-_107203897 3.41 ENSRNOT00000086263
leucine rich repeat containing 6
chr16_+_72010106 3.34 ENSRNOT00000058330
ADAM metallopeptidase domain 5
chr9_+_99753099 3.32 ENSRNOT00000052361
olfactory receptor 1350
chr7_-_36660141 3.27 ENSRNOT00000012363
nudix hydrolase 4
chr3_-_57646572 3.21 ENSRNOT00000076202
methyltransferase like 8
chr3_-_15278645 3.18 ENSRNOT00000032204
tubulin tyrosine ligase like11
chr3_+_148654668 3.18 ENSRNOT00000081370
transmembrane 9 superfamily member 4
chr18_+_51523758 3.15 ENSRNOT00000078518
GRAM domain containing 3
chr8_+_126975833 3.14 ENSRNOT00000088348

chr9_+_73418607 3.12 ENSRNOT00000092547
microtubule-associated protein 2
chr20_+_1764794 3.11 ENSRNOT00000075084
olfactory receptor 1736
chr17_+_32973695 3.11 ENSRNOT00000065674
similar to OTTMUSP00000000621
chr9_-_80167033 2.98 ENSRNOT00000023530
insulin-like growth factor binding protein 5
chr11_-_29710849 2.91 ENSRNOT00000029345
keratin associated protein 11-1
chr6_+_101532518 2.78 ENSRNOT00000075054
gephyrin
chr11_+_74834050 2.64 ENSRNOT00000002333
ATPase 13A4
chr15_+_4554603 2.62 ENSRNOT00000075153
potassium two pore domain channel subfamily K member 5
chr11_-_32550539 2.56 ENSRNOT00000002715
regulator of calcineurin 1
chr11_-_45667254 2.44 ENSRNOT00000072466
olfactory receptor 1535
chr11_-_28979169 2.42 ENSRNOT00000061601

chr3_+_95233874 2.40 ENSRNOT00000079743
hypothetical protein LOC691083
chr2_+_145174876 2.39 ENSRNOT00000040631
mab-21 like 1
chr4_-_156563438 2.39 ENSRNOT00000045305
vomeronasal 2 receptor, 51
chr16_-_75107931 2.38 ENSRNOT00000058066
defensin beta 15
chr13_-_76049363 2.38 ENSRNOT00000075865
ENSRNOT00000007455
BMP/retinoic acid inducible neural specific 2
chr1_+_172822544 2.38 ENSRNOT00000090018

chr9_+_99745714 2.27 ENSRNOT00000022152
olfactory receptor 1349
chr3_-_160561741 2.27 ENSRNOT00000018364
potassium voltage-gated channel, modifier subfamily S, member 1
chr2_-_35503638 2.23 ENSRNOT00000007560
olfactory receptor 144-like
chr7_-_6971557 2.19 ENSRNOT00000050153
olfactory receptor 960
chr2_+_66940057 2.19 ENSRNOT00000043050
cadherin 9
chr20_-_11626876 2.10 ENSRNOT00000001635
keratin associated protein 12-1-like
chr8_-_49075892 2.10 ENSRNOT00000082687
archain 1
chr10_-_44746549 2.10 ENSRNOT00000003841
family with sequence similarity 183, member B
chrX_-_84768463 2.08 ENSRNOT00000088570
CHM, Rab escort protein 1
chr2_+_158097843 2.06 ENSRNOT00000016541
pentraxin 3
chr20_+_31234493 2.01 ENSRNOT00000000675
neuropeptide FF receptor 1
chr13_+_9479995 1.99 ENSRNOT00000072979
olfactory receptor 6C4-like
chrX_+_43831892 1.97 ENSRNOT00000005120
myosin light chain 6B
chr17_-_42740021 1.97 ENSRNOT00000023063
Prolactin family 3, subfamily a, member 1
chr15_+_28894627 1.97 ENSRNOT00000017795
olfactory receptor 1643
chr4_-_167068838 1.95 ENSRNOT00000029713
taste receptor, type 2, member 125
chr2_+_243577082 1.84 ENSRNOT00000016556
alcohol dehydrogenase 6A (class V)
chr10_+_91126689 1.83 ENSRNOT00000004046
N-myristoyltransferase 1
chr1_+_225037737 1.83 ENSRNOT00000077959
BSCL2, seipin lipid droplet biogenesis associated
chr5_-_102743417 1.76 ENSRNOT00000067389
basonuclin 2
chr11_-_29298339 1.76 ENSRNOT00000061592

chr3_+_56056925 1.74 ENSRNOT00000088351
ENSRNOT00000010508
kelch-like family member 23
chr3_+_75970593 1.73 ENSRNOT00000075834
olfactory receptor 592
chr4_+_181874861 1.72 ENSRNOT00000002527
coiled-coil domain containing 91
chr15_+_56666012 1.71 ENSRNOT00000013408
5-hydroxytryptamine receptor 2A
chr10_+_110445797 1.68 ENSRNOT00000054920
nuclear prelamin A recognition factor
chr6_+_124123228 1.67 ENSRNOT00000005329
proteasome 26S subunit, ATPase 1
chr2_+_206314213 1.64 ENSRNOT00000056068
BCL2-like 15
chr1_-_103811148 1.60 ENSRNOT00000030162
MAS-related G protein-coupled receptor, member X2-like
chr20_-_29199224 1.57 ENSRNOT00000071477
mitochondrial calcium uniporter
chr8_+_82038967 1.54 ENSRNOT00000079535
myosin VA
chr3_-_165700489 1.49 ENSRNOT00000017008
zinc finger protein 93
chr1_-_170694872 1.47 ENSRNOT00000075443
olfactory receptor 2D3-like
chr1_+_230217215 1.44 ENSRNOT00000072772
similar to olfactory receptor 1467
chr1_+_229461127 1.39 ENSRNOT00000035813
olfactory receptor 332
chr3_-_21904133 1.38 ENSRNOT00000090576
ENSRNOT00000087611
ENSRNOT00000066377
spermatid perinuclear RNA binding protein
chr2_-_25235275 1.35 ENSRNOT00000061580
F2R like trypsin receptor 1
chr1_+_168575090 1.35 ENSRNOT00000048299
olfactory receptor 103
chr1_-_167971151 1.34 ENSRNOT00000043023
olfactory receptor 53
chr17_-_87826421 1.34 ENSRNOT00000068156
Rho GTPase activating protein 21
chr10_+_88997399 1.19 ENSRNOT00000027116
MLX, MAX dimerization protein
chr15_+_11298478 1.17 ENSRNOT00000007672
leucine rich repeat containing 3B
chr8_+_42663633 1.17 ENSRNOT00000048537
olfactory receptor 1266
chrX_+_66314418 1.17 ENSRNOT00000035405
G protein-coupled receptor 15-like
chr16_-_12538117 1.13 ENSRNOT00000046081

chr3_-_76696107 1.12 ENSRNOT00000044692
olfactory receptor 629
chr7_+_9294709 1.10 ENSRNOT00000048396
olfactory receptor 1065
chr3_-_154627257 1.09 ENSRNOT00000018328
transglutaminase 2
chr3_-_73124644 1.08 ENSRNOT00000012711
olfactory receptor 455
chr2_+_178117466 1.05 ENSRNOT00000065115
ENSRNOT00000084198
similar to hypothetical protein FLJ25371
chr10_+_104582955 1.03 ENSRNOT00000009733
unkempt family zinc finger
chr7_-_145062956 1.02 ENSRNOT00000055274
similar to CDNA sequence BC048502
chr1_+_169590308 0.98 ENSRNOT00000023147
olfactory receptor 155
chr20_-_3751994 0.97 ENSRNOT00000072288
POU class 5 homeobox 1
chr13_+_67545430 0.96 ENSRNOT00000003405
phosducin
chr1_+_86533127 0.95 ENSRNOT00000052208
vomeronasal 1 receptor 4
chr1_-_22488131 0.95 ENSRNOT00000051416
trace-amine-associated receptor 7d
chr16_+_23553647 0.92 ENSRNOT00000041994
pleckstrin and Sec7 domain containing 3
chr2_+_46203776 0.92 ENSRNOT00000074056
olfactory receptor 147-like
chr16_+_12510827 0.90 ENSRNOT00000077763

chr3_+_103556674 0.90 ENSRNOT00000050168
olfactory receptor 792
chr3_+_77431389 0.88 ENSRNOT00000042848
olfactory receptor 660
chr9_+_17920677 0.88 ENSRNOT00000045763
spermatogenesis associated, serine-rich 1
chr4_+_87312766 0.87 ENSRNOT00000052126
vomeronasal 1 receptor 71
chr4_-_82141385 0.87 ENSRNOT00000008447
homeobox A3
chr3_+_147952879 0.85 ENSRNOT00000031922
defensin beta 20
chr19_+_9668186 0.84 ENSRNOT00000016563
CCR4-NOT transcription complex, subunit 1
chr1_-_169770188 0.81 ENSRNOT00000072602
olfactory receptor 165
chr1_+_140998240 0.79 ENSRNOT00000023506
ENSRNOT00000090897
abhydrolase domain containing 2
chr11_+_70056624 0.78 ENSRNOT00000002447

chr9_+_50966766 0.78 ENSRNOT00000076636
ERCC excision repair 5, endonuclease
chr7_-_59882077 0.76 ENSRNOT00000068774
myelin regulatory factor-like
chr1_+_75326217 0.76 ENSRNOT00000044964
vomeronasal 1 receptor 62
chr4_+_72637035 0.76 ENSRNOT00000007235
olfactory receptor 819
chr1_-_71909138 0.71 ENSRNOT00000029591
NLR family, pyrin domain containing 9
chr2_-_60657712 0.71 ENSRNOT00000040348
retinoic acid induced 14
chr4_+_72502935 0.70 ENSRNOT00000007168
olfactory receptor 813
chr13_-_89545182 0.70 ENSRNOT00000078402
Purkinje cell protein 4-like 1
chr3_-_10144388 0.69 ENSRNOT00000042495
ABL proto-oncogene 1, non-receptor tyrosine kinase
chr14_+_22091777 0.69 ENSRNOT00000072483
sulfotransferase family 1D, member 1
chr7_-_6691679 0.69 ENSRNOT00000075430
olfactory receptor 959
chr16_-_12194118 0.65 ENSRNOT00000071517
similar to hypothetical protein 4930474N05
chr1_+_88113445 0.60 ENSRNOT00000056955
gametogenetin
chr7_+_2504695 0.60 ENSRNOT00000003965
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr7_+_9262982 0.59 ENSRNOT00000047647
olfactory receptor 1063
chr4_+_87516218 0.57 ENSRNOT00000090182
vomeronasal 1 receptor 66
chr8_-_87419564 0.57 ENSRNOT00000015365
filamin A interacting protein 1
chr11_-_82893845 0.56 ENSRNOT00000075306
eukaryotic translation initiation factor 4 gamma 1-like

Network of associatons between targets according to the STRING database.

First level regulatory network of Meox1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 18.7 GO:0060354 negative regulation of cell adhesion molecule production(GO:0060354)
4.3 12.8 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
3.4 13.6 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
2.4 7.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
2.4 9.6 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
1.9 5.8 GO:0015680 intracellular copper ion transport(GO:0015680)
1.9 7.6 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
1.8 5.4 GO:0035880 embryonic nail plate morphogenesis(GO:0035880) positive regulation of mesenchymal cell apoptotic process(GO:2001055)
1.8 5.4 GO:0071469 cellular response to alkaline pH(GO:0071469)
1.8 5.3 GO:0048377 lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378) regulation of cardiac ventricle development(GO:1904412)
1.7 19.0 GO:0015747 urate transport(GO:0015747)
1.7 6.8 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
1.4 5.7 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
1.4 4.2 GO:0043134 hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
1.4 6.8 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
1.3 10.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
1.3 3.8 GO:0071422 succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
1.2 13.8 GO:0010649 regulation of cell communication by electrical coupling(GO:0010649)
1.1 18.8 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
1.1 7.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
1.1 6.4 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
1.0 4.2 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
1.0 4.0 GO:0002933 lipid hydroxylation(GO:0002933) alkaloid catabolic process(GO:0009822)
0.9 2.8 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.8 10.9 GO:0099562 maintenance of postsynaptic specialization structure(GO:0098880) maintenance of postsynaptic density structure(GO:0099562)
0.8 3.3 GO:1901906 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.8 14.4 GO:0060134 prepulse inhibition(GO:0060134)
0.7 3.0 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.7 5.2 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.7 2.1 GO:0021699 cerebellar cortex maturation(GO:0021699)
0.7 12.7 GO:0021860 pyramidal neuron development(GO:0021860)
0.6 1.8 GO:0018201 peptidyl-glycine modification(GO:0018201)
0.6 3.6 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.6 3.4 GO:0060023 soft palate development(GO:0060023)
0.6 1.7 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.6 4.5 GO:0015884 folic acid transport(GO:0015884)
0.5 6.5 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.5 1.4 GO:0043311 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) positive regulation of eosinophil degranulation(GO:0043311) regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949) positive regulation of renin secretion into blood stream(GO:1900135) positive regulation of eosinophil activation(GO:1902568)
0.4 8.2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.4 1.5 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.4 3.8 GO:0061635 regulation of protein complex stability(GO:0061635)
0.4 9.1 GO:0006855 drug transmembrane transport(GO:0006855)
0.4 3.4 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.4 3.8 GO:0006670 sphingosine metabolic process(GO:0006670)
0.4 1.1 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.4 5.0 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.3 4.9 GO:0016322 neuron remodeling(GO:0016322)
0.3 1.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.3 1.0 GO:0090081 regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.3 3.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.3 3.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.3 21.1 GO:0042446 hormone biosynthetic process(GO:0042446)
0.3 4.2 GO:0051639 actin filament network formation(GO:0051639)
0.3 29.0 GO:0046849 bone remodeling(GO:0046849)
0.2 2.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.2 0.7 GO:1903210 transitional stage B cell differentiation(GO:0002332) transitional one stage B cell differentiation(GO:0002333) glomerular visceral epithelial cell apoptotic process(GO:1903210) positive regulation of actin filament binding(GO:1904531) positive regulation of actin binding(GO:1904618) activation of protein kinase C activity(GO:1990051)
0.2 3.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.2 23.3 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.2 0.9 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.2 2.6 GO:0051151 locomotion involved in locomotory behavior(GO:0031987) negative regulation of smooth muscle cell differentiation(GO:0051151)
0.2 6.3 GO:0097352 autophagosome maturation(GO:0097352)
0.2 4.3 GO:0097503 sialylation(GO:0097503)
0.2 0.8 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.2 1.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.6 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1 2.3 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.1 1.8 GO:0034389 lipid particle organization(GO:0034389)
0.1 1.0 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 6.1 GO:0035082 axoneme assembly(GO:0035082)
0.1 0.8 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 1.0 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.7 GO:0000103 sulfate assimilation(GO:0000103)
0.1 5.0 GO:0008347 glial cell migration(GO:0008347)
0.1 3.1 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 8.0 GO:0035690 cellular response to drug(GO:0035690)
0.1 1.8 GO:0043586 tongue development(GO:0043586)
0.1 9.5 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.1 10.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 3.5 GO:0015914 phospholipid transport(GO:0015914)
0.1 4.2 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.3 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.3 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.9 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 2.4 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.8 GO:0048240 sperm capacitation(GO:0048240)
0.0 1.9 GO:0050909 sensory perception of taste(GO:0050909)
0.0 1.7 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 31.6 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 7.7 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.0 2.7 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 1.9 GO:0008584 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 0.6 GO:0007566 embryo implantation(GO:0007566)
0.0 0.2 GO:0006415 translational termination(GO:0006415)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.5 GO:0031230 intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)
2.1 12.7 GO:0097441 basilar dendrite(GO:0097441)
1.1 3.4 GO:0005592 collagen type XI trimer(GO:0005592)
1.0 14.8 GO:0072687 meiotic spindle(GO:0072687)
0.7 5.7 GO:0032584 growth cone membrane(GO:0032584)
0.7 10.9 GO:0005883 neurofilament(GO:0005883)
0.6 3.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.5 2.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.5 1.5 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.5 3.0 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.4 16.0 GO:0046930 pore complex(GO:0046930)
0.3 4.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.3 1.6 GO:1990246 uniplex complex(GO:1990246)
0.2 4.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 1.7 GO:0005638 lamin filament(GO:0005638)
0.2 5.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 1.7 GO:0031595 nuclear proteasome complex(GO:0031595)
0.2 3.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 11.6 GO:0016459 myosin complex(GO:0016459)
0.2 0.8 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.2 4.2 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.2 7.2 GO:0043034 costamere(GO:0043034)
0.1 4.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 2.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 1.4 GO:0031143 pseudopodium(GO:0031143)
0.1 1.7 GO:0070852 cell body fiber(GO:0070852)
0.1 86.5 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 11.6 GO:0042734 presynaptic membrane(GO:0042734)
0.1 2.8 GO:0060077 inhibitory synapse(GO:0060077)
0.1 9.6 GO:0031225 anchored component of membrane(GO:0031225)
0.1 6.2 GO:0005581 collagen trimer(GO:0005581)
0.1 0.6 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 14.8 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 5.3 GO:0030426 growth cone(GO:0030426)
0.1 8.8 GO:0001650 fibrillar center(GO:0001650)
0.1 5.3 GO:0005901 caveola(GO:0005901)
0.1 0.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 13.8 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 2.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.2 GO:0043195 terminal bouton(GO:0043195)
0.0 21.3 GO:0043025 neuronal cell body(GO:0043025)
0.0 4.6 GO:0031514 motile cilium(GO:0031514)
0.0 13.7 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.0 GO:0005844 polysome(GO:0005844)
0.0 0.3 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.8 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 4.8 GO:0005635 nuclear envelope(GO:0005635)
0.0 2.8 GO:0000139 Golgi membrane(GO:0000139)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 11.6 GO:0017042 glycosylceramidase activity(GO:0017042)
2.9 11.6 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
2.8 22.1 GO:0008430 selenium binding(GO:0008430)
2.4 7.2 GO:0004657 proline dehydrogenase activity(GO:0004657)
2.3 6.8 GO:0004736 pyruvate carboxylase activity(GO:0004736)
2.1 10.3 GO:0005534 galactose binding(GO:0005534)
1.9 19.0 GO:1901702 urate transmembrane transporter activity(GO:0015143) efflux transmembrane transporter activity(GO:0015562) salt transmembrane transporter activity(GO:1901702)
1.7 23.2 GO:0015250 water channel activity(GO:0015250)
1.6 21.0 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
1.5 7.5 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
1.3 3.8 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
1.3 3.8 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
1.2 5.8 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
1.2 3.5 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
1.1 5.7 GO:0005042 netrin receptor activity(GO:0005042)
1.1 4.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.9 29.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.9 5.3 GO:0098821 BMP receptor activity(GO:0098821)
0.8 10.9 GO:0098879 structural constituent of postsynaptic specialization(GO:0098879) structural constituent of postsynaptic density(GO:0098919)
0.8 3.3 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.8 23.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.7 5.0 GO:0001595 angiotensin receptor activity(GO:0001595)
0.7 2.8 GO:0008940 nitrate reductase activity(GO:0008940)
0.6 2.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.6 7.3 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451)
0.6 3.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.6 10.5 GO:0005523 tropomyosin binding(GO:0005523)
0.6 1.7 GO:0071886 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding(GO:0071886)
0.5 1.6 GO:0015292 uniporter activity(GO:0015292)
0.5 4.8 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.5 18.9 GO:0070330 aromatase activity(GO:0070330)
0.4 5.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.4 5.4 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.4 3.0 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.4 12.7 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.3 1.4 GO:0015057 thrombin receptor activity(GO:0015057)
0.3 5.0 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.3 6.5 GO:0008199 ferric iron binding(GO:0008199)
0.3 2.1 GO:0001849 complement component C1q binding(GO:0001849)
0.3 14.4 GO:0005504 fatty acid binding(GO:0005504)
0.3 8.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.3 1.7 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.2 1.0 GO:1990715 mRNA CDS binding(GO:1990715)
0.2 6.4 GO:0005109 frizzled binding(GO:0005109)
0.1 2.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 3.1 GO:0002162 dystroglycan binding(GO:0002162)
0.1 4.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 14.0 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 5.9 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 3.6 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.0 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 1.0 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 2.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.6 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.8 GO:0000405 bubble DNA binding(GO:0000405)
0.1 1.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 9.6 GO:0003823 antigen binding(GO:0003823)
0.1 1.7 GO:0005521 lamin binding(GO:0005521)
0.1 2.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.7 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 1.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 1.5 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 4.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 8.8 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.1 0.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 1.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 10.3 GO:0003774 motor activity(GO:0003774)
0.1 0.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 2.0 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 0.7 GO:0070097 delta-catenin binding(GO:0070097)
0.0 3.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.3 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.9 GO:0071837 HMG box domain binding(GO:0071837)
0.0 7.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 7.3 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 2.6 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 1.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.8 GO:0016410 N-acyltransferase activity(GO:0016410)
0.0 2.4 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 9.1 GO:0005549 odorant binding(GO:0005549)
0.0 4.6 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 12.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 3.3 GO:0003924 GTPase activity(GO:0003924)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 5.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 9.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 5.3 PID BMP PATHWAY BMP receptor signaling
0.1 4.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 8.4 PID CMYB PATHWAY C-MYB transcription factor network
0.1 2.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 3.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 3.6 PID TNF PATHWAY TNF receptor signaling pathway
0.1 2.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 1.4 ST GA12 PATHWAY G alpha 12 Pathway
0.1 5.9 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 3.1 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.0 PID HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 18.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
1.5 23.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
1.2 18.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.9 10.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.9 12.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.6 8.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.5 11.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.4 5.7 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.4 5.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.3 9.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.3 11.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.3 11.2 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.3 4.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.3 4.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.3 10.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.3 4.9 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 5.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.2 2.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.2 4.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 1.7 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 5.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 6.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 2.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 2.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 10.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.6 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.6 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 5.7 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 1.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.2 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism