ISMARA results: Mecp2

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Mecp2

Z-value: 2.56

Motif logo

Transcription factors associated with Mecp2

Gene Symbol	Gene ID	Gene Info
Mecp2 NCBI RGD Ensembl	ENSRNOG00000056659	methyl CpG binding protein 2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Mecp2	rn6_v1_chrX_+_156655960_156655960	0.38	1.8e-12	Click!

Activity profile of Mecp2 motif

Sorted Z-values of Mecp2 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr8_+_127271289 Show fit	71.62	ENSRNOT00000015113	Itga9 NCBI RGD Ensembl Show fit	integrin subunit alpha 9
chr10_-_11174861 Show fit	56.57	ENSRNOT00000006680	Glis2 NCBI RGD Ensembl Show fit	GLIS family zinc finger 2
chr7_-_142260896 Show fit	54.15	ENSRNOT00000073536	Smagp NCBI RGD Ensembl Show fit	small cell adhesion glycoprotein
chr18_-_48384645 Show fit	52.82	ENSRNOT00000023485	Ppic NCBI RGD Ensembl Show fit	peptidylprolyl isomerase C
chr9_-_81400987 Show fit	52.78	ENSRNOT00000035277	Tns1 NCBI RGD Ensembl Show fit	tensin 1
chr3_-_51297852 Show fit	51.52	ENSRNOT00000001607	Cobll1 NCBI RGD Ensembl Show fit	cordon-bleu WH2 repeat protein-like 1
chr7_+_130474508 Show fit	51.32	ENSRNOT00000085191	Shank3 NCBI RGD Ensembl Show fit	SH3 and multiple ankyrin repeat domains 3
chr11_+_82466071 Show fit	50.30	ENSRNOT00000036958	Igf2bp2 NCBI RGD Ensembl Show fit	insulin-like growth factor 2 mRNA binding protein 2
chrX_-_157139291 Show fit	49.66	ENSRNOT00000092123	Slc6a8 NCBI RGD Ensembl Show fit	solute carrier family 6 member 8
chr10_+_84182118 Show fit	49.61	ENSRNOT00000011027	Hoxb3 NCBI RGD Ensembl Show fit	homeo box B3
chr3_-_175601127 Show fit	46.54	ENSRNOT00000081226	Lama5 NCBI RGD Ensembl Show fit	laminin subunit alpha 5
chr6_+_49968473 Show fit	44.87	ENSRNOT00000007466	Fam110c NCBI RGD Ensembl Show fit	family with sequence similarity 110, member C
chr3_+_45683993 Show fit	44.29	ENSRNOT00000038983	Tanc1 NCBI RGD Ensembl Show fit	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr10_-_64202380 Show fit	43.63	ENSRNOT00000008982	Rflnb NCBI RGD Ensembl Show fit	refilin B
chr8_+_99977334 Show fit	41.37	ENSRNOT00000085808 ENSRNOT00000056704 ENSRNOT00000041859	Plod2 NCBI RGD Ensembl Show fit	procollagen lysine, 2-oxoglutarate 5-dioxygenase 2
chr1_+_150797084 Show fit	41.30	ENSRNOT00000018990	Nox4 NCBI RGD Ensembl Show fit	NADPH oxidase 4
chr17_-_19703681 Show fit	41.26	ENSRNOT00000024021	Mylip NCBI RGD Ensembl Show fit	myosin regulatory light chain interacting protein
chr10_+_86367596 Show fit	40.42	ENSRNOT00000049070 ENSRNOT00000009114 ENSRNOT00000078744	Erbb2 NCBI RGD Ensembl Show fit	erb-b2 receptor tyrosine kinase 2
chr6_-_25616995 Show fit	39.50	ENSRNOT00000077894	Fosl2 NCBI RGD Ensembl Show fit	FOS like 2, AP-1 transcription factor subunit
chr7_+_130474279 Show fit	39.47	ENSRNOT00000092388	Shank3 NCBI RGD Ensembl Show fit	SH3 and multiple ankyrin repeat domains 3
chr4_-_66380734 Show fit	38.74	ENSRNOT00000009194	Klrg2 NCBI RGD Ensembl Show fit	killer cell lectin like receptor G2
chr8_-_87158368 Show fit	38.37	ENSRNOT00000077071	Col12a1 NCBI RGD Ensembl Show fit	collagen type XII alpha 1 chain
chr5_+_133221139 Show fit	37.84	ENSRNOT00000047522	Trabd2b NCBI RGD Ensembl Show fit	TraB domain containing 2B
chr7_-_23594133 Show fit	37.12	ENSRNOT00000005746	Timp3 NCBI RGD Ensembl Show fit	TIMP metallopeptidase inhibitor 3
chr1_+_221099998 Show fit	35.92	ENSRNOT00000028262	Ltbp3 NCBI RGD Ensembl Show fit	latent transforming growth factor beta binding protein 3
chr3_-_55822551 Show fit	35.90	ENSRNOT00000082624	Lrp2 NCBI RGD Ensembl Show fit	LDL receptor related protein 2
chr20_-_14020007 Show fit	35.86	ENSRNOT00000093521	Ggt1 NCBI RGD Ensembl Show fit	gamma-glutamyltransferase 1
chr4_+_175431904 Show fit	35.67	ENSRNOT00000032843	Pde3a NCBI RGD Ensembl Show fit	phosphodiesterase 3A
chr1_+_219233750 Show fit	35.28	ENSRNOT00000024112	Acy3 NCBI RGD Ensembl Show fit	aminoacylase 3
chr7_-_144993652 Show fit	34.93	ENSRNOT00000087748	Itga5 NCBI RGD Ensembl Show fit	integrin subunit alpha 5
chr1_-_82120902 Show fit	34.72	ENSRNOT00000027684	Erf NCBI RGD Ensembl Show fit	Ets2 repressor factor
chr10_+_63803309 Show fit	34.61	ENSRNOT00000036666	Myo1c NCBI RGD Ensembl Show fit	myosin 1C
chr8_+_71168097 Show fit	34.19	ENSRNOT00000081375	Rbpms2 NCBI RGD Ensembl Show fit	RNA binding protein with multiple splicing 2
chr1_+_242959488 Show fit	33.83	ENSRNOT00000015668	Dock8 NCBI RGD Ensembl Show fit	dedicator of cytokinesis 8
chr7_-_3010350 Show fit	32.84	ENSRNOT00000006796	Erbb3 NCBI RGD Ensembl Show fit	erb-b2 receptor tyrosine kinase 3
chr7_+_130498199 Show fit	32.66	ENSRNOT00000092684 ENSRNOT00000092431	Shank3 NCBI RGD Ensembl Show fit	SH3 and multiple ankyrin repeat domains 3
chr11_-_70322690 Show fit	32.58	ENSRNOT00000002443	Heg1 NCBI RGD Ensembl Show fit	heart development protein with EGF-like domains 1
chr6_-_21600451 Show fit	32.36	ENSRNOT00000047674	Ltbp1 NCBI RGD Ensembl Show fit	latent transforming growth factor beta binding protein 1
chr16_-_22561496 Show fit	32.18	ENSRNOT00000016543	Lpl NCBI RGD Ensembl Show fit	lipoprotein lipase
chr3_+_6430201 Show fit	32.11	ENSRNOT00000086352	Col5a1 NCBI RGD Ensembl Show fit	collagen type V alpha 1 chain
chr8_-_55408464 Show fit	32.06	ENSRNOT00000066893	Sik2 NCBI RGD Ensembl Show fit	salt-inducible kinase 2
chr14_+_33010300 Show fit	31.87	ENSRNOT00000002809	Igfbp7 NCBI RGD Ensembl Show fit	insulin-like growth factor binding protein 7
chr10_-_88874528 Show fit	31.77	ENSRNOT00000026783	Ptrf NCBI RGD Ensembl Show fit	polymerase I and transcript release factor
chr6_+_788548 Show fit	31.65	ENSRNOT00000005983	Crim1 NCBI RGD Ensembl Show fit	cysteine rich transmembrane BMP regulator 1
chr8_-_33661049 Show fit	31.59	ENSRNOT00000068037	Fli1 NCBI RGD Ensembl Show fit	Fli-1 proto-oncogene, ETS transcription factor
chr1_+_128924966 Show fit	30.83	ENSRNOT00000019267	Igf1r NCBI RGD Ensembl Show fit	insulin-like growth factor 1 receptor
chr1_+_56242346 Show fit	30.29	ENSRNOT00000019317	Smoc2 NCBI RGD Ensembl Show fit	SPARC related modular calcium binding 2
chr4_-_66624912 Show fit	30.12	ENSRNOT00000064891	Hipk2 NCBI RGD Ensembl Show fit	homeodomain interacting protein kinase 2
chr13_+_34610684 Show fit	29.82	ENSRNOT00000093019 ENSRNOT00000003280	Tfcp2l1 NCBI RGD Ensembl Show fit	transcription factor CP2-like 1
chr11_+_87722350 Show fit	29.81	ENSRNOT00000000313	Scarf2 NCBI RGD Ensembl Show fit	scavenger receptor class F, member 2
chr5_-_152762165 Show fit	29.45	ENSRNOT00000022921	Selenon NCBI RGD Ensembl Show fit	selenoprotein N
chr8_+_115069095 Show fit	29.44	ENSRNOT00000014770	Dusp7 NCBI RGD Ensembl Show fit	dual specificity phosphatase 7
chr20_+_22913694 Show fit	29.37	ENSRNOT00000067920	Reep3 NCBI RGD Ensembl Show fit	receptor accessory protein 3
chr2_-_204625743 Show fit	29.33	ENSRNOT00000022182	Vangl1 NCBI RGD Ensembl Show fit	VANGL planar cell polarity protein 1
chr15_-_82482009 Show fit	29.31	ENSRNOT00000011926	Dach1 NCBI RGD Ensembl Show fit	dachshund family transcription factor 1
chr1_+_33910912 Show fit	29.31	ENSRNOT00000044690	Irx1 NCBI RGD Ensembl Show fit	iroquois homeobox 1
chr10_+_89167146 Show fit	29.12	ENSRNOT00000043953	Ramp2 NCBI RGD Ensembl Show fit	receptor activity modifying protein 2
chr3_+_80362858 Show fit	29.10	ENSRNOT00000021353 ENSRNOT00000086242	Lrp4 NCBI RGD Ensembl Show fit	LDL receptor related protein 4
chr1_-_153740905 Show fit	29.01	ENSRNOT00000023239	Prss23 NCBI RGD Ensembl Show fit	protease, serine, 23
chr9_+_81672758 Show fit	28.87	ENSRNOT00000020646	Ctdsp1 NCBI RGD Ensembl Show fit	CTD small phosphatase 1
chr2_-_28801223 Show fit	28.74	ENSRNOT00000020726	Tmem171 NCBI RGD Ensembl Show fit	transmembrane protein 171
chr5_+_80920568 Show fit	28.63	ENSRNOT00000076467 ENSRNOT00000076111 ENSRNOT00000040898	Pappa NCBI RGD Ensembl Show fit	pregnancy-associated plasma protein A
chr1_+_32221636 Show fit	28.56	ENSRNOT00000022346 ENSRNOT00000089941	Slc6a18 NCBI RGD Ensembl Show fit	solute carrier family 6 member 18
chr12_+_17735740 Show fit	28.53	ENSRNOT00000001775	Pdgfa NCBI RGD Ensembl Show fit	platelet derived growth factor subunit A
chr11_-_25456836 Show fit	28.49	ENSRNOT00000085444	Adamts5 NCBI RGD Ensembl Show fit	ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr2_-_203494391 Show fit	28.21	ENSRNOT00000021162	Ptgfrn NCBI RGD Ensembl Show fit	prostaglandin F2 receptor inhibitor
chr3_-_5975734 Show fit	28.01	ENSRNOT00000081376	Vav2 NCBI RGD Ensembl Show fit	vav guanine nucleotide exchange factor 2
chr2_+_189169877 Show fit	27.99	ENSRNOT00000028225	She NCBI RGD Ensembl Show fit	Src homology 2 domain containing E
chr19_+_23389375 Show fit	27.97	ENSRNOT00000018629	Sall1 NCBI RGD Ensembl Show fit	spalt-like transcription factor 1
chr16_+_83522162 Show fit	27.86	ENSRNOT00000057386	Col4a1 NCBI RGD Ensembl Show fit	collagen type IV alpha 1 chain
chr5_-_114014277 Show fit	27.84	ENSRNOT00000011731	Jun NCBI RGD Ensembl Show fit	Jun proto-oncogene, AP-1 transcription factor subunit
chr10_+_73279119 Show fit	27.79	ENSRNOT00000004698	Tbx2 NCBI RGD Ensembl Show fit	T-box 2
chr17_-_13812615 Show fit	27.79	ENSRNOT00000019473 ENSRNOT00000085581	S1pr3 NCBI RGD Ensembl Show fit	sphingosine-1-phosphate receptor 3
chr6_+_48866601 Show fit	27.75	ENSRNOT00000077321 ENSRNOT00000079891	Pxdn NCBI RGD Ensembl Show fit	peroxidasin
chr11_-_38103290 Show fit	27.70	ENSRNOT00000066413	Tmprss2 NCBI RGD Ensembl Show fit	transmembrane protease, serine 2
chr15_+_33108671 Show fit	27.54	ENSRNOT00000015468	Lrp10 NCBI RGD Ensembl Show fit	LDL receptor related protein 10
chr6_+_24160226 Show fit	27.32	ENSRNOT00000091904	Lbh NCBI RGD Ensembl Show fit	limb bud and heart development
chr1_-_146289465 Show fit	27.31	ENSRNOT00000017362	Abhd17c NCBI RGD Ensembl Show fit	abhydrolase domain containing 17C
chr16_-_19777414 Show fit	27.18	ENSRNOT00000022898	Nr2f6 NCBI RGD Ensembl Show fit	nuclear receptor subfamily 2, group F, member 6
chr8_-_68966108 Show fit	27.12	ENSRNOT00000012155	Smad6 NCBI RGD Ensembl Show fit	SMAD family member 6
chr11_-_67037115 Show fit	26.97	ENSRNOT00000003137	Ildr1 NCBI RGD Ensembl Show fit	immunoglobulin-like domain containing receptor 1
chr10_+_106065712 Show fit	26.89	ENSRNOT00000003690	Sec14l1 NCBI RGD Ensembl Show fit	SEC14-like lipid binding 1
chr5_+_59128315 Show fit	26.87	ENSRNOT00000021802	Npr2 NCBI RGD Ensembl Show fit	natriuretic peptide receptor 2
chr1_-_47331412 Show fit	26.57	ENSRNOT00000046746	Ezr NCBI RGD Ensembl Show fit	ezrin
chr7_-_139254551 Show fit	26.56	ENSRNOT00000083182	Rapgef3 NCBI RGD Ensembl Show fit	Rap guanine nucleotide exchange factor 3
chr2_+_251634431 Show fit	26.49	ENSRNOT00000045016	Ddah1 NCBI RGD Ensembl Show fit	dimethylarginine dimethylaminohydrolase 1
chr7_+_126619196 Show fit	26.14	ENSRNOT00000030082	Ppara NCBI RGD Ensembl Show fit	peroxisome proliferator activated receptor alpha
chr7_+_42269784 Show fit	25.94	ENSRNOT00000008471 ENSRNOT00000007231	Kitlg NCBI RGD Ensembl Show fit	KIT ligand
chr7_-_126913585 Show fit	25.70	ENSRNOT00000036025	Celsr1 NCBI RGD Ensembl Show fit	cadherin, EGF LAG seven-pass G-type receptor 1
chr3_-_156340913 Show fit	25.56	ENSRNOT00000021452	Mafb NCBI RGD Ensembl Show fit	MAF bZIP transcription factor B
chr8_-_13109487 Show fit	25.54	ENSRNOT00000061616	Amotl1 NCBI RGD Ensembl Show fit	angiomotin-like 1
chr8_-_97647072 Show fit	25.53	ENSRNOT00000030645	Tbc1d2b NCBI RGD Ensembl Show fit	TBC1 domain family, member 2B
chr19_+_18079094 Show fit	25.53	ENSRNOT00000029415	Tox3 NCBI RGD Ensembl Show fit	TOX high mobility group box family member 3
chr10_+_15672382 Show fit	25.48	ENSRNOT00000027965	Rhbdf1 NCBI RGD Ensembl Show fit	rhomboid 5 homolog 1
chr10_+_89166890 Show fit	25.46	ENSRNOT00000088331	Ramp2 NCBI RGD Ensembl Show fit	receptor activity modifying protein 2
chr1_-_141893674 Show fit	25.43	ENSRNOT00000019059 ENSRNOT00000085988	Idh2 NCBI RGD Ensembl Show fit	isocitrate dehydrogenase (NADP(+)) 2, mitochondrial
chr7_-_139318455 Show fit	25.39	ENSRNOT00000092029	Hdac7 NCBI RGD Ensembl Show fit	histone deacetylase 7
chr1_-_131454689 Show fit	25.34	ENSRNOT00000014152	Nr2f2 NCBI RGD Ensembl Show fit	nuclear receptor subfamily 2, group F, member 2
chr9_-_19372673 Show fit	25.26	ENSRNOT00000073667 ENSRNOT00000079517	Clic5 NCBI RGD Ensembl Show fit	chloride intracellular channel 5
chr14_-_20816588 Show fit	25.25	ENSRNOT00000033806	Slc4a4 NCBI RGD Ensembl Show fit	solute carrier family 4 member 4
chr3_-_152222647 Show fit	25.08	ENSRNOT00000026820	Nfs1 NCBI RGD Ensembl Show fit	NFS1 cysteine desulfurase
chr13_-_70174565 Show fit	24.98	ENSRNOT00000067135	Rgl1 NCBI RGD Ensembl Show fit	ral guanine nucleotide dissociation stimulator,-like 1
chr12_-_22726982 Show fit	24.86	ENSRNOT00000001921	Plod3 NCBI RGD Ensembl Show fit	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr18_+_65814026 Show fit	24.84	ENSRNOT00000016112	Mbd2 NCBI RGD Ensembl Show fit	methyl-CpG binding domain protein 2
chr3_-_151688149 Show fit	24.81	ENSRNOT00000072945	Nfs1 NCBI RGD Ensembl Show fit	NFS1 cysteine desulfurase
chr20_+_44680449 Show fit	24.77	ENSRNOT00000000728	Traf3ip2 NCBI RGD Ensembl Show fit	Traf3 interacting protein 2
chr20_+_33359196 Show fit	24.47	ENSRNOT00000000462	Dcbld1 NCBI RGD Ensembl Show fit	discoidin, CUB and LCCL domain containing 1
chr14_+_3506339 Show fit	24.28	ENSRNOT00000002867	Tgfbr3 NCBI RGD Ensembl Show fit	transforming growth factor beta receptor 3
chr16_-_71319449 Show fit	24.27	ENSRNOT00000029284	Fgfr1 NCBI RGD Ensembl Show fit	Fibroblast growth factor receptor 1
chr16_-_73410777 Show fit	24.25	ENSRNOT00000024128	Sfrp1 NCBI RGD Ensembl Show fit	secreted frizzled-related protein 1
chr8_-_21995806 Show fit	23.94	ENSRNOT00000028034	S1pr2 NCBI RGD Ensembl Show fit	sphingosine-1-phosphate receptor 2
chr1_+_177495782 Show fit	23.92	ENSRNOT00000021020	Tead1 NCBI RGD Ensembl Show fit	TEA domain transcription factor 1
chr1_+_221673590 Show fit	23.86	ENSRNOT00000038016	Cdc42bpg NCBI RGD Ensembl Show fit	CDC42 binding protein kinase gamma
chr17_+_30556884 Show fit	23.84	ENSRNOT00000080929 ENSRNOT00000022022	Eci2 NCBI RGD Ensembl Show fit	enoyl-CoA delta isomerase 2
chr17_+_62262129 Show fit	23.52	ENSRNOT00000073575	Fzd8 NCBI RGD Ensembl Show fit	frizzled class receptor 8
chr5_-_172623899 Show fit	23.51	ENSRNOT00000080591	Ski NCBI RGD Ensembl Show fit	SKI proto-oncogene
chr10_+_4719713 Show fit	23.48	ENSRNOT00000003412	Litaf NCBI RGD Ensembl Show fit	lipopolysaccharide-induced TNF factor
chr7_+_144628120 Show fit	23.39	ENSRNOT00000022247	Hoxc5 NCBI RGD Ensembl Show fit	homeo box C5
chr3_-_9262628 Show fit	23.39	ENSRNOT00000013286	Aif1l NCBI RGD Ensembl Show fit	allograft inflammatory factor 1-like
chr4_-_58893170 Show fit	23.37	ENSRNOT00000077406	Podxl NCBI RGD Ensembl Show fit	podocalyxin-like
chr10_+_13723405 Show fit	23.34	ENSRNOT00000072789	Abca3 NCBI RGD Ensembl Show fit	ATP binding cassette subfamily A member 3
chr14_+_78213635 Show fit	23.32	ENSRNOT00000010541	Evc NCBI RGD Ensembl Show fit	EvC ciliary complex subunit 1
chr12_+_17736287 Show fit	23.31	ENSRNOT00000091476	Pdgfa NCBI RGD Ensembl Show fit	platelet derived growth factor subunit A
chr15_-_47800024 Show fit	23.28	ENSRNOT00000072997 ENSRNOT00000016616	Msra NCBI RGD Ensembl Show fit	methionine sulfoxide reductase A
chr5_+_56425024 Show fit	23.23	ENSRNOT00000008337	Aco1 NCBI RGD Ensembl Show fit	aconitase 1
chr1_-_89084859 Show fit	23.19	ENSRNOT00000032026	Cox6b1 NCBI RGD Ensembl Show fit	cytochrome c oxidase subunit 6B1
chr1_-_267245636 Show fit	23.15	ENSRNOT00000082799	Sh3pxd2a NCBI RGD Ensembl Show fit	SH3 and PX domains 2A
chr3_-_149905944 Show fit	22.93	ENSRNOT00000021715	Snta1 NCBI RGD Ensembl Show fit	syntrophin, alpha 1
chr1_+_32199810 Show fit	22.92	ENSRNOT00000036714	Slc6a19 NCBI RGD Ensembl Show fit	solute carrier family 6 member 19
chr19_-_15840990 Show fit	22.92	ENSRNOT00000015583	Irx3 NCBI RGD Ensembl Show fit	iroquois homeobox 3
chr6_-_44361908 Show fit	22.88	ENSRNOT00000009491	Id2 NCBI RGD Ensembl Show fit	inhibitor of DNA binding 2, HLH protein
chr2_-_147693082 Show fit	22.73	ENSRNOT00000022507	Wwtr1 NCBI RGD Ensembl Show fit	WW domain containing transcription regulator 1
chr8_+_48805684 Show fit	22.59	ENSRNOT00000064041	Bcl9l NCBI RGD Ensembl Show fit	B-cell CLL/lymphoma 9-like
chr17_+_83221827 Show fit	22.58	ENSRNOT00000000155	Plxdc2 NCBI RGD Ensembl Show fit	plexin domain containing 2
chr4_-_82173207 Show fit	22.56	ENSRNOT00000074167	Hoxa5 NCBI RGD Ensembl Show fit	homeo box A5
chr14_-_87465374 Show fit	22.47	ENSRNOT00000088355	Igfbp3 NCBI RGD Ensembl Show fit	insulin-like growth factor binding protein 3
chr5_-_134207847 Show fit	22.47	ENSRNOT00000083686 ENSRNOT00000088209 ENSRNOT00000051252	Cyp4a2 NCBI RGD Ensembl Show fit	cytochrome P450, family 4, subfamily a, polypeptide 2
chr9_-_73871888 Show fit	22.41	ENSRNOT00000017686	Acadl NCBI RGD Ensembl Show fit	acyl-CoA dehydrogenase, long chain
chr8_+_50310405 Show fit	22.26	ENSRNOT00000073507	Sik3 NCBI RGD Ensembl Show fit	SIK family kinase 3
chr12_-_16934706 Show fit	22.12	ENSRNOT00000001720	Mafk NCBI RGD Ensembl Show fit	MAF bZIP transcription factor K
chr3_-_130114770 Show fit	22.08	ENSRNOT00000010638	Jag1 NCBI RGD Ensembl Show fit	jagged 1
chr9_-_9985630 Show fit	22.06	ENSRNOT00000071780	Crb3 NCBI RGD Ensembl Show fit	crumbs 3, cell polarity complex component
chr16_-_19399851 Show fit	22.04	ENSRNOT00000089056 ENSRNOT00000021073	Tpm4 NCBI RGD Ensembl Show fit	tropomyosin 4
chr4_-_157829241 Show fit	22.02	ENSRNOT00000026184	Ltbr NCBI RGD Ensembl Show fit	lymphotoxin beta receptor
chr5_-_152920343 Show fit	21.90	ENSRNOT00000022956	Man1c1 NCBI RGD Ensembl Show fit	mannosidase, alpha, class 1C, member 1
chr1_+_15412603 Show fit	21.87	ENSRNOT00000051496 ENSRNOT00000067070	Map3k5 NCBI RGD Ensembl Show fit	mitogen-activated protein kinase kinase kinase 5
chr8_+_122439328 Show fit	21.77	ENSRNOT00000013632	Glb1 NCBI RGD Ensembl Show fit	galactosidase, beta 1
chr1_+_137014272 Show fit	21.67	ENSRNOT00000014802	Akap13 NCBI RGD Ensembl Show fit	A-kinase anchoring protein 13
chr5_-_173081839 Show fit	21.66	ENSRNOT00000066880	Mmp23 NCBI RGD Ensembl Show fit	matrix metallopeptidase 23
chr4_-_58875753 Show fit	21.63	ENSRNOT00000016991	Podxl NCBI RGD Ensembl Show fit	podocalyxin-like
chr15_-_51855325 Show fit	21.59	ENSRNOT00000011663	Pdlim2 NCBI RGD Ensembl Show fit	PDZ and LIM domain 2
chr14_+_34727915 Show fit	21.57	ENSRNOT00000085089	Kdr NCBI RGD Ensembl Show fit	kinase insert domain receptor
chr16_-_71319052 Show fit	21.52	ENSRNOT00000050980	Fgfr1 NCBI RGD Ensembl Show fit	Fibroblast growth factor receptor 1
chr10_+_71159869 Show fit	21.47	ENSRNOT00000075977 ENSRNOT00000047427	Hnf1b NCBI RGD Ensembl Show fit	HNF1 homeobox B
chr10_+_84718824 Show fit	21.42	ENSRNOT00000055464	Copz2 NCBI RGD Ensembl Show fit	coatomer protein complex, subunit zeta 2
chr9_+_20264418 Show fit	21.38	ENSRNOT00000051841	Atn1 NCBI RGD Ensembl Show fit	atrophin 1
chr5_+_159845774 Show fit	21.32	ENSRNOT00000012328	Epha2 NCBI RGD Ensembl Show fit	Eph receptor A2
chr5_-_156141537 Show fit	21.28	ENSRNOT00000019004	Alpl NCBI RGD Ensembl Show fit	alkaline phosphatase, liver/bone/kidney
chr15_-_18882959 Show fit	21.26	ENSRNOT00000066546 ENSRNOT00000088264	Flnb NCBI RGD Ensembl Show fit	filamin B
chr6_+_109466060 Show fit	21.26	ENSRNOT00000011339	Jdp2 NCBI RGD Ensembl Show fit	Jun dimerization protein 2
chr3_+_71114100 Show fit	21.12	ENSRNOT00000088549 ENSRNOT00000006961	Itgav NCBI RGD Ensembl Show fit	integrin subunit alpha V
chr13_-_50916982 Show fit	21.08	ENSRNOT00000004408	Btg2 NCBI RGD Ensembl Show fit	BTG anti-proliferation factor 2
chr14_-_16979760 Show fit	21.02	ENSRNOT00000003020	Stbd1 NCBI RGD Ensembl Show fit	starch binding domain 1
chr5_+_167952728 Show fit	21.02	ENSRNOT00000085315	Errfi1 NCBI RGD Ensembl Show fit	ERBB receptor feedback inhibitor 1
chr15_+_24942218 Show fit	20.95	ENSRNOT00000016629	Peli2 NCBI RGD Ensembl Show fit	pellino E3 ubiquitin protein ligase family member 2
chr3_-_173953684 Show fit	20.93	ENSRNOT00000090468	Ppp1r3d NCBI RGD Ensembl Show fit	protein phosphatase 1, regulatory subunit 3D
chr9_-_38495126 Show fit	20.90	ENSRNOT00000016933 ENSRNOT00000090385	Rab23 NCBI RGD Ensembl Show fit	RAB23, member RAS oncogene family
chr17_-_31569904 Show fit	20.90	ENSRNOT00000023962	Ripk1 NCBI RGD Ensembl Show fit	receptor interacting serine/threonine kinase 1
chr12_+_943006 Show fit	20.89	ENSRNOT00000001449	Kl NCBI RGD Ensembl Show fit	Klotho
chr5_-_151856256 Show fit	20.79	ENSRNOT00000081470	Zdhhc18 NCBI RGD Ensembl Show fit	zinc finger, DHHC-type containing 18
chr7_+_53630621 Show fit	20.66	ENSRNOT00000067011 ENSRNOT00000080598	Csrp2 NCBI RGD Ensembl Show fit	cysteine and glycine-rich protein 2
chr4_-_147893992 Show fit	20.60	ENSRNOT00000032158	Plxnd1 NCBI RGD Ensembl Show fit	plexin D1
chr14_-_7325645 Show fit	20.48	ENSRNOT00000066071	Aff1 NCBI RGD Ensembl Show fit	AF4/FMR2 family, member 1
chr13_-_110077946 Show fit	20.48	ENSRNOT00000000078	Ppp2r5a NCBI RGD Ensembl Show fit	protein phosphatase 2, regulatory subunit B', alpha
chr10_+_5433248 Show fit	20.38	ENSRNOT00000003615	Emp2 NCBI RGD Ensembl Show fit	epithelial membrane protein 2
chr8_-_47404010 Show fit	20.37	ENSRNOT00000038647	Tmem136 NCBI RGD Ensembl Show fit	transmembrane protein 136
chr1_-_218920094 Show fit	20.33	ENSRNOT00000022213	Lrp5 NCBI RGD Ensembl Show fit	LDL receptor related protein 5
chr8_+_99625545 Show fit	20.29	ENSRNOT00000010689 ENSRNOT00000056727	Plscr1 NCBI RGD Ensembl Show fit	phospholipid scramblase 1
chr2_-_142885604 Show fit	20.12	ENSRNOT00000031487	Frem2 NCBI RGD Ensembl Show fit	Fras1 related extracellular matrix protein 2
chr5_-_153625869 Show fit	20.10	ENSRNOT00000024464	Clic4 NCBI RGD Ensembl Show fit	chloride intracellular channel 4
chr4_-_100660140 Show fit	20.09	ENSRNOT00000020005	Tcf7l1 NCBI RGD Ensembl Show fit	transcription factor 7 like 1
chr10_+_89181180 Show fit	20.06	ENSRNOT00000078931 ENSRNOT00000027770	Wnk4 NCBI RGD Ensembl Show fit	WNK lysine deficient protein kinase 4
chr6_-_103313074 Show fit	20.04	ENSRNOT00000083677	Zfp36l1 NCBI RGD Ensembl Show fit	zinc finger protein 36, C3H type-like 1
chr20_+_55594676 Show fit	19.98	ENSRNOT00000057010	Sim1 NCBI RGD Ensembl Show fit	single-minded family bHLH transcription factor 1
chr8_-_6203515 Show fit	19.97	ENSRNOT00000087278 ENSRNOT00000031189 ENSRNOT00000008074 ENSRNOT00000085285 ENSRNOT00000007866	Yap1 NCBI RGD Ensembl Show fit	yes-associated protein 1
chr1_-_193328371 Show fit	19.93	ENSRNOT00000019304 ENSRNOT00000031770 ENSRNOT00000019309	Arhgap17 NCBI RGD Ensembl Show fit	Rho GTPase activating protein 17
chr20_+_7484550 Show fit	19.89	ENSRNOT00000044395	Anks1a NCBI RGD Ensembl Show fit	ankyrin repeat and sterile alpha motif domain containing 1A
chr7_-_51353068 Show fit	19.89	ENSRNOT00000008222	Pawr NCBI RGD Ensembl Show fit	pro-apoptotic WT1 regulator
chr10_+_35726544 Show fit	19.87	ENSRNOT00000004323	Mgat4b NCBI RGD Ensembl Show fit	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr19_-_37303788 Show fit	19.71	ENSRNOT00000084734	Fhod1 NCBI RGD Ensembl Show fit	formin homology 2 domain containing 1
chr10_-_56558487 Show fit	19.63	ENSRNOT00000023256	Slc2a4 NCBI RGD Ensembl Show fit	solute carrier family 2 member 4
chr10_+_109665682 Show fit	19.58	ENSRNOT00000054963	Slc25a10 NCBI RGD Ensembl Show fit	solute carrier family 25 member 10
chr20_-_4943564 Show fit	19.58	ENSRNOT00000049310	RT1-CE1 NCBI RGD Ensembl Show fit	RT1 class I, locus1
chr17_-_24182425 Show fit	19.57	ENSRNOT00000024206	Mcur1 NCBI RGD Ensembl Show fit	mitochondrial calcium uniporter regulator 1
chr5_-_173622645 Show fit	19.54	ENSRNOT00000045678	Agrn NCBI RGD Ensembl Show fit	agrin
chr10_-_39373437 Show fit	19.52	ENSRNOT00000058907	Slc22a5 NCBI RGD Ensembl Show fit	solute carrier family 22 member 5
chr10_-_91448477 Show fit	19.50	ENSRNOT00000038836	Arhgap27 NCBI RGD Ensembl Show fit	Rho GTPase activating protein 27
chr5_+_2813131 Show fit	19.47	ENSRNOT00000009530	Sbspon NCBI RGD Ensembl Show fit	somatomedin B and thrombospondin, type 1 domain containing
chr10_+_84167331 Show fit	19.41	ENSRNOT00000010965	Hoxb4 NCBI RGD Ensembl Show fit	homeo box B4
chr14_+_34727623 Show fit	19.39	ENSRNOT00000071405 ENSRNOT00000090183	Kdr NCBI RGD Ensembl Show fit	kinase insert domain receptor

Network of associatons between targets according to the STRING database.

First level regulatory network of Mecp2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
35.9	35.9	GO:1902460	regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
24.7	123.4	GO:1904717	regulation of AMPA glutamate receptor clustering(GO:1904717)
22.1	66.2	GO:0046947	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
20.6	61.7	GO:0060764	cell-cell signaling involved in mammary gland development(GO:0060764)
18.9	56.6	GO:0060994	regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
17.3	51.8	GO:0060683	regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling(GO:0060683) embryonic lung development(GO:1990401)
17.1	51.4	GO:0021847	ventricular zone neuroblast division(GO:0021847) fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development(GO:0035607)
17.1	51.2	GO:0018283	metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
15.5	93.0	GO:1904426	positive regulation of GTP binding(GO:1904426)
15.4	46.1	GO:0061181	regulation of chondrocyte development(GO:0061181)
15.3	15.3	GO:0010512	negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
14.6	58.4	GO:0021615	glossopharyngeal nerve morphogenesis(GO:0021615)
14.4	43.1	GO:2000384	regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
14.1	14.1	GO:0000821	regulation of arginine metabolic process(GO:0000821)
14.0	42.1	GO:1903943	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
13.8	13.8	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
13.8	41.5	GO:1901220	regulation of cardiac chamber morphogenesis(GO:1901219) negative regulation of cardiac chamber morphogenesis(GO:1901220)
13.1	52.6	GO:0072268	pattern specification involved in metanephros development(GO:0072268)
12.9	12.9	GO:0072554	blood vessel lumenization(GO:0072554)
12.9	38.6	GO:0061441	renal artery morphogenesis(GO:0061441)
12.3	37.0	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
12.3	49.0	GO:1903225	negative regulation of endodermal cell differentiation(GO:1903225)
12.1	24.3	GO:0010159	specification of organ position(GO:0010159)
12.1	24.2	GO:2000053	regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
12.1	60.5	GO:0044691	tooth eruption(GO:0044691)
12.0	36.0	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
11.2	67.2	GO:0048597	post-embryonic camera-type eye morphogenesis(GO:0048597)
10.9	10.9	GO:0061349	planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354)
10.5	21.0	GO:0046102	inosine metabolic process(GO:0046102)
10.4	41.4	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
10.3	82.3	GO:0010668	ectodermal cell differentiation(GO:0010668)
10.2	20.5	GO:0010979	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
10.2	30.7	GO:0060849	lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
10.0	50.2	GO:1904684	negative regulation of metalloendopeptidase activity(GO:1904684)
10.0	40.0	GO:0044332	Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332)
9.8	39.3	GO:1903976	negative regulation of glial cell migration(GO:1903976)
9.8	39.1	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
9.7	29.2	GO:0006579	amino-acid betaine catabolic process(GO:0006579)
9.7	29.2	GO:0002462	tolerance induction to nonself antigen(GO:0002462)
9.6	38.3	GO:0071896	protein localization to adherens junction(GO:0071896)
9.5	18.9	GO:0097018	renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532)
9.4	47.1	GO:0014858	positive regulation of skeletal muscle cell proliferation(GO:0014858)
9.4	65.6	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
9.3	37.3	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
9.2	55.4	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
9.2	36.8	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
9.1	27.2	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
9.1	27.2	GO:0015744	succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
9.1	27.2	GO:0000294	nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
9.1	72.5	GO:0015871	choline transport(GO:0015871)
9.0	27.0	GO:0042706	eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
9.0	35.9	GO:0031179	peptide modification(GO:0031179)
8.9	26.7	GO:1903626	positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
8.8	61.8	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
8.8	17.6	GO:0090118	receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
8.8	26.3	GO:0072156	distal tubule morphogenesis(GO:0072156)
8.7	17.5	GO:0009957	epidermal cell fate specification(GO:0009957)
8.6	17.3	GO:0071306	cellular response to vitamin E(GO:0071306)
8.6	17.2	GO:1903181	regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
8.6	34.3	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
8.6	25.7	GO:0090164	asymmetric Golgi ribbon formation(GO:0090164)
8.5	25.5	GO:0003365	establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
8.5	34.0	GO:0033088	negative regulation of immature T cell proliferation in thymus(GO:0033088)
8.5	42.4	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
8.4	16.9	GO:0006344	maintenance of chromatin silencing(GO:0006344)
8.4	33.4	GO:0006172	ADP biosynthetic process(GO:0006172)
8.3	24.9	GO:0001966	thigmotaxis(GO:0001966)
8.3	16.5	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
8.3	16.5	GO:0002840	T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
8.2	16.3	GO:2001201	regulation of transforming growth factor-beta secretion(GO:2001201)
8.1	89.4	GO:0060242	contact inhibition(GO:0060242)
8.1	24.3	GO:0060939	cardiac fibroblast cell differentiation(GO:0060935) cardiac fibroblast cell development(GO:0060936) epicardium-derived cardiac fibroblast cell differentiation(GO:0060938) epicardium-derived cardiac fibroblast cell development(GO:0060939)
8.0	8.0	GO:0018307	enzyme active site formation(GO:0018307)
7.9	23.8	GO:0003430	growth plate cartilage chondrocyte growth(GO:0003430)
7.9	15.8	GO:0045404	interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
7.9	15.8	GO:0003192	mitral valve formation(GO:0003192)
7.8	31.3	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
7.8	46.9	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
7.7	30.8	GO:0003342	proepicardium development(GO:0003342) septum transversum development(GO:0003343)
7.7	7.7	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
7.4	7.4	GO:0072240	DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240)
7.4	22.2	GO:2001205	negative regulation of osteoclast development(GO:2001205)
7.4	22.2	GO:2000338	chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
7.4	22.1	GO:0061443	endocardial cushion cell differentiation(GO:0061443)
7.4	29.4	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
7.3	43.9	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
7.3	21.8	GO:1901873	regulation of post-translational protein modification(GO:1901873)
7.2	21.7	GO:0033512	L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
7.2	21.5	GO:0061206	mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
7.2	21.5	GO:0060734	regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
7.1	28.6	GO:1904387	cellular response to L-phenylalanine derivative(GO:1904387)
7.1	14.3	GO:0021563	glossopharyngeal nerve development(GO:0021563)
7.1	21.3	GO:0071529	cementum mineralization(GO:0071529)
7.1	21.2	GO:1903406	regulation of sodium:potassium-exchanging ATPase activity(GO:1903406)
7.0	21.0	GO:1903445	protein transport from ciliary membrane to plasma membrane(GO:1903445)
7.0	41.9	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
7.0	20.9	GO:0060545	positive regulation of necroptotic process(GO:0060545)
6.9	6.9	GO:0061073	ciliary body morphogenesis(GO:0061073)
6.9	55.5	GO:0097084	vascular smooth muscle cell development(GO:0097084)
6.9	34.3	GO:0070666	mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
6.8	20.4	GO:0032789	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
6.8	13.6	GO:1900158	negative regulation of bone mineralization involved in bone maturation(GO:1900158)
6.7	33.7	GO:1904504	regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
6.7	47.0	GO:0003176	aortic valve development(GO:0003176) aortic valve morphogenesis(GO:0003180)
6.7	13.3	GO:0003275	apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
6.6	26.6	GO:1902896	terminal web assembly(GO:1902896)
6.6	26.6	GO:0021571	rhombomere 5 development(GO:0021571)
6.6	6.6	GO:0044330	canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330)
6.5	19.6	GO:2001045	negative regulation of integrin-mediated signaling pathway(GO:2001045)
6.5	19.5	GO:1901723	negative regulation of glomerular mesangial cell proliferation(GO:0072125) negative regulation of glomerulus development(GO:0090194) negative regulation of cell proliferation involved in kidney development(GO:1901723)
6.5	38.9	GO:0035331	negative regulation of hippo signaling(GO:0035331)
6.4	25.7	GO:0010626	negative regulation of Schwann cell proliferation(GO:0010626)
6.4	19.1	GO:0030091	protein repair(GO:0030091)
6.3	19.0	GO:0045210	FasL biosynthetic process(GO:0045210)
6.3	18.9	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
6.2	24.9	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
6.2	24.8	GO:1903243	negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
6.2	18.6	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
6.1	18.3	GO:0042822	pyridoxal phosphate metabolic process(GO:0042822)
6.0	12.1	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
5.9	17.8	GO:1902748	positive regulation of lens fiber cell differentiation(GO:1902748)
5.9	23.6	GO:0042891	antibiotic transport(GO:0042891)
5.9	17.7	GO:0071461	cellular response to redox state(GO:0071461)
5.9	17.6	GO:0035880	embryonic nail plate morphogenesis(GO:0035880)
5.9	5.9	GO:0003162	atrioventricular node development(GO:0003162)
5.8	23.4	GO:0006212	uracil catabolic process(GO:0006212)
5.8	23.3	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
5.8	11.6	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
5.7	5.7	GO:0061017	hepatoblast differentiation(GO:0061017)
5.7	17.2	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
5.7	34.2	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
5.6	39.5	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
5.6	22.5	GO:0048252	lauric acid metabolic process(GO:0048252)
5.6	39.2	GO:0070836	caveola assembly(GO:0070836)
5.6	22.2	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
5.5	16.6	GO:1903903	regulation of establishment of T cell polarity(GO:1903903)
5.5	33.2	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
5.5	16.6	GO:0060319	regulation of primitive erythrocyte differentiation(GO:0010725) primitive erythrocyte differentiation(GO:0060319)
5.5	32.8	GO:1903142	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
5.4	10.9	GO:1902463	protein localization to cell leading edge(GO:1902463)
5.4	38.0	GO:0051414	response to cortisol(GO:0051414)
5.3	26.6	GO:1902414	protein localization to cell junction(GO:1902414)
5.3	5.3	GO:0060300	regulation of cytokine activity(GO:0060300)
5.3	31.6	GO:0045634	regulation of melanocyte differentiation(GO:0045634)
5.3	26.3	GO:0060282	positive regulation of oocyte development(GO:0060282)
5.2	15.7	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
5.2	15.6	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
5.2	15.6	GO:0032902	nerve growth factor production(GO:0032902)
5.2	25.9	GO:2000196	positive regulation of female gonad development(GO:2000196)
5.2	25.8	GO:0044351	macropinocytosis(GO:0044351)
5.2	15.5	GO:0046643	regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
5.2	30.9	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
5.1	20.6	GO:1902510	regulation of apoptotic DNA fragmentation(GO:1902510)
5.1	15.4	GO:0046544	development of secondary male sexual characteristics(GO:0046544)
5.1	15.2	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
5.1	10.1	GO:0036023	embryonic skeletal limb joint morphogenesis(GO:0036023)
5.0	10.1	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
5.0	5.0	GO:0002084	protein depalmitoylation(GO:0002084)
5.0	15.1	GO:0036066	protein O-linked fucosylation(GO:0036066)
5.0	25.1	GO:0048539	bone marrow development(GO:0048539)
5.0	35.0	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
5.0	15.0	GO:0061043	positive regulation of vascular wound healing(GO:0035470) regulation of vascular wound healing(GO:0061043)
5.0	19.9	GO:0048842	positive regulation of axon extension involved in axon guidance(GO:0048842)
5.0	14.9	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
4.9	14.8	GO:1903847	regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
4.9	9.9	GO:0042637	catagen(GO:0042637) regulation of catagen(GO:0051794)
4.9	4.9	GO:1904580	regulation of intracellular mRNA localization(GO:1904580)
4.9	4.9	GO:0036506	maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
4.8	14.5	GO:0042938	dipeptide transport(GO:0042938)
4.8	14.5	GO:0061314	Notch signaling involved in heart development(GO:0061314)
4.8	19.3	GO:0016332	establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
4.8	28.7	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)
4.8	14.4	GO:0090210	regulation of establishment of blood-brain barrier(GO:0090210)
4.7	28.3	GO:0072658	maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660)
4.7	65.9	GO:0051639	actin filament network formation(GO:0051639)
4.7	4.7	GO:0035993	deltoid tuberosity development(GO:0035993)
4.7	9.4	GO:1900222	negative regulation of beta-amyloid clearance(GO:1900222)
4.7	37.4	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
4.7	14.0	GO:1903116	gastrin-induced gastric acid secretion(GO:0001698) positive regulation of actin filament-based movement(GO:1903116)
4.6	9.3	GO:2000468	regulation of peroxidase activity(GO:2000468)
4.6	9.2	GO:0003164	His-Purkinje system development(GO:0003164)
4.6	9.2	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
4.6	27.3	GO:1904674	positive regulation of somatic stem cell population maintenance(GO:1904674)
4.5	18.1	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
4.5	13.5	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
4.5	9.0	GO:0043311	regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
4.5	9.0	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
4.5	13.4	GO:0006121	mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
4.5	31.3	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
4.4	22.2	GO:0007039	protein catabolic process in the vacuole(GO:0007039)
4.4	17.7	GO:0035772	interleukin-13-mediated signaling pathway(GO:0035772)
4.4	53.1	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
4.4	13.3	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
4.4	35.3	GO:0019388	galactose catabolic process(GO:0019388)
4.4	43.8	GO:0018158	protein oxidation(GO:0018158)
4.4	8.7	GO:0034165	positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
4.4	47.9	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
4.3	25.9	GO:2000394	positive regulation of lamellipodium morphogenesis(GO:2000394)
4.3	8.6	GO:0036378	calcitriol biosynthetic process from calciol(GO:0036378)
4.3	13.0	GO:0006742	NADP catabolic process(GO:0006742) NAD catabolic process(GO:0019677)
4.3	17.2	GO:0002018	renin-angiotensin regulation of aldosterone production(GO:0002018)
4.3	25.7	GO:0006549	isoleucine metabolic process(GO:0006549)
4.3	4.3	GO:1903895	negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
4.3	4.3	GO:0003273	cell migration involved in endocardial cushion formation(GO:0003273)
4.2	25.4	GO:0072104	glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
4.2	8.5	GO:1901300	positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
4.2	12.7	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
4.2	33.8	GO:0010838	positive regulation of keratinocyte proliferation(GO:0010838)
4.2	20.9	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
4.2	41.9	GO:1901550	regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
4.2	8.3	GO:0003278	apoptotic process involved in heart morphogenesis(GO:0003278)
4.2	16.6	GO:0033625	positive regulation of integrin activation(GO:0033625)
4.2	33.2	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
4.1	53.7	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
4.1	20.6	GO:0051136	regulation of NK T cell differentiation(GO:0051136)
4.1	16.4	GO:0060454	positive regulation of gastric acid secretion(GO:0060454)
4.1	12.3	GO:0097187	dentinogenesis(GO:0097187)
4.1	8.2	GO:0048550	negative regulation of pinocytosis(GO:0048550)
4.1	4.1	GO:0060266	negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
4.1	12.2	GO:1902746	regulation of lens fiber cell differentiation(GO:1902746)
4.1	28.5	GO:0070782	phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
4.1	12.2	GO:0033580	protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
4.1	28.5	GO:0072257	metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
4.0	8.1	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
4.0	4.0	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
4.0	20.1	GO:0015780	nucleotide-sugar transport(GO:0015780)
4.0	4.0	GO:0061197	fungiform papilla development(GO:0061196) fungiform papilla morphogenesis(GO:0061197)
4.0	24.1	GO:0072675	osteoclast fusion(GO:0072675)
4.0	12.0	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
4.0	12.0	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
4.0	47.8	GO:0036303	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
4.0	4.0	GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity(GO:2000277)
4.0	15.8	GO:0042126	nitrate metabolic process(GO:0042126)
3.9	47.2	GO:0035563	positive regulation of chromatin binding(GO:0035563)
3.9	31.3	GO:0043615	astrocyte cell migration(GO:0043615)
3.9	7.8	GO:0007403	glial cell fate determination(GO:0007403)
3.9	42.9	GO:0006527	arginine catabolic process(GO:0006527)
3.9	27.3	GO:0043102	amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
3.9	15.5	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
3.8	26.9	GO:0001922	B-1 B cell homeostasis(GO:0001922)
3.8	26.9	GO:0006868	glutamine transport(GO:0006868)
3.8	3.8	GO:1905024	regulation of potassium ion export across plasma membrane(GO:1903764) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024) regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905031)
3.8	26.6	GO:0008063	Toll signaling pathway(GO:0008063)
3.8	7.6	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
3.8	3.8	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
3.8	30.1	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
3.8	22.5	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
3.7	29.8	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
3.7	11.1	GO:2000407	regulation of T cell extravasation(GO:2000407) positive regulation of T cell extravasation(GO:2000409)
3.7	11.1	GO:0015938	coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
3.7	14.8	GO:0044725	chromatin reprogramming in the zygote(GO:0044725)
3.7	3.7	GO:0097324	melanocyte migration(GO:0097324)
3.7	11.0	GO:0035582	sequestering of BMP in extracellular matrix(GO:0035582)
3.7	18.3	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
3.6	32.8	GO:0060056	mammary gland involution(GO:0060056)
3.6	7.3	GO:0034436	glycoprotein transport(GO:0034436)
3.6	10.9	GO:0051933	amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
3.6	7.2	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
3.6	14.4	GO:0019262	N-acetylneuraminate catabolic process(GO:0019262)
3.6	17.9	GO:0001555	oocyte growth(GO:0001555)
3.6	17.9	GO:0006309	apoptotic DNA fragmentation(GO:0006309)
3.6	17.8	GO:0000066	mitochondrial ornithine transport(GO:0000066)
3.5	10.6	GO:0061205	paramesonephric duct development(GO:0061205)
3.5	14.1	GO:0042473	outer ear morphogenesis(GO:0042473)
3.5	77.2	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
3.5	10.5	GO:0001543	ovarian follicle rupture(GO:0001543)
3.5	14.0	GO:0099545	trans-synaptic signaling by trans-synaptic complex(GO:0099545)
3.5	3.5	GO:0051122	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
3.5	14.0	GO:1990859	response to endothelin(GO:1990839) cellular response to endothelin(GO:1990859)
3.5	13.9	GO:0070813	hydrogen sulfide metabolic process(GO:0070813)
3.5	10.4	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
3.5	10.4	GO:0015882	L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
3.4	3.4	GO:0061298	retina vasculature development in camera-type eye(GO:0061298)
3.4	10.3	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
3.4	13.7	GO:0070086	ubiquitin-dependent endocytosis(GO:0070086)
3.4	13.7	GO:0032792	negative regulation of CREB transcription factor activity(GO:0032792)
3.4	13.7	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
3.4	34.3	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
3.4	27.2	GO:0043116	negative regulation of vascular permeability(GO:0043116)
3.4	6.8	GO:0006106	fumarate metabolic process(GO:0006106)
3.4	6.8	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)
3.4	13.4	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
3.4	10.1	GO:1902037	negative regulation of hematopoietic stem cell differentiation(GO:1902037)
3.4	13.4	GO:0021540	corpus callosum morphogenesis(GO:0021540)
3.4	6.7	GO:0010871	negative regulation of receptor biosynthetic process(GO:0010871)
3.3	33.3	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
3.3	10.0	GO:0007386	compartment pattern specification(GO:0007386)
3.3	3.3	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
3.3	6.6	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
3.3	9.9	GO:0010796	regulation of multivesicular body size(GO:0010796)
3.3	19.8	GO:0045990	carbon catabolite regulation of transcription(GO:0045990)
3.3	9.9	GO:1902659	regulation of glucose mediated signaling pathway(GO:1902659)
3.3	9.9	GO:0065001	specification of axis polarity(GO:0065001)
3.3	3.3	GO:0031077	post-embryonic camera-type eye development(GO:0031077)
3.3	9.9	GO:0046167	glycerol-3-phosphate biosynthetic process(GO:0046167)
3.3	9.8	GO:0040032	post-embryonic body morphogenesis(GO:0040032)
3.3	29.4	GO:0071374	cellular response to parathyroid hormone stimulus(GO:0071374)
3.3	16.3	GO:0015801	aromatic amino acid transport(GO:0015801)
3.2	32.5	GO:0048757	endosome to melanosome transport(GO:0035646) pigment accumulation(GO:0043476) cellular pigment accumulation(GO:0043482) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
3.2	3.2	GO:0019521	aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
3.2	12.9	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
3.2	9.6	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
3.2	25.7	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
3.2	16.0	GO:0089700	protein kinase D signaling(GO:0089700)
3.2	9.6	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
3.2	6.4	GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
3.2	38.1	GO:0034389	lipid particle organization(GO:0034389)
3.2	9.5	GO:2001274	negative regulation of glucose import in response to insulin stimulus(GO:2001274)
3.2	9.5	GO:1900104	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
3.2	3.2	GO:0002051	osteoblast fate commitment(GO:0002051)
3.1	40.9	GO:0003334	keratinocyte development(GO:0003334)
3.1	15.7	GO:0030213	hyaluronan biosynthetic process(GO:0030213)
3.1	15.7	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
3.1	6.2	GO:0040009	regulation of growth rate(GO:0040009)
3.1	12.4	GO:0033030	negative regulation of neutrophil apoptotic process(GO:0033030)
3.1	18.6	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
3.1	15.5	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
3.1	6.2	GO:0003099	positive regulation of the force of heart contraction by epinephrine-norepinephrine(GO:0001997) vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
3.1	6.2	GO:1904849	positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
3.1	3.1	GO:0010286	heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
3.1	6.2	GO:0021943	formation of radial glial scaffolds(GO:0021943)
3.1	12.3	GO:0009597	detection of virus(GO:0009597)
3.1	21.6	GO:0006907	pinocytosis(GO:0006907)
3.1	18.5	GO:0033623	regulation of integrin activation(GO:0033623)
3.1	6.2	GO:0043696	dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
3.1	15.4	GO:0031947	negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947)
3.1	21.5	GO:0000103	sulfate assimilation(GO:0000103)
3.1	9.2	GO:0034224	cellular response to zinc ion starvation(GO:0034224)
3.1	12.3	GO:0046881	positive regulation of follicle-stimulating hormone secretion(GO:0046881)
3.1	12.3	GO:0038158	granulocyte colony-stimulating factor signaling pathway(GO:0038158)
3.1	76.6	GO:0042554	superoxide anion generation(GO:0042554)
3.1	6.1	GO:0035963	cellular response to interleukin-13(GO:0035963)
3.1	3.1	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
3.0	3.0	GO:1905076	regulation of interleukin-17 secretion(GO:1905076) negative regulation of interleukin-17 secretion(GO:1905077)
3.0	51.6	GO:0010718	positive regulation of epithelial to mesenchymal transition(GO:0010718)
3.0	9.1	GO:0032380	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
3.0	18.1	GO:0070673	response to interleukin-18(GO:0070673)
3.0	15.1	GO:0030223	neutrophil differentiation(GO:0030223)
3.0	72.3	GO:0006099	tricarboxylic acid cycle(GO:0006099)
3.0	18.1	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
3.0	30.0	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
3.0	20.9	GO:0006968	cellular defense response(GO:0006968)
3.0	29.8	GO:0097012	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
3.0	50.6	GO:0036336	dendritic cell migration(GO:0036336)
3.0	8.9	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
3.0	20.8	GO:0015705	iodide transport(GO:0015705)
3.0	62.0	GO:0008340	determination of adult lifespan(GO:0008340)
2.9	8.8	GO:0042412	taurine biosynthetic process(GO:0042412)
2.9	26.5	GO:0005980	glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
2.9	5.9	GO:0035330	regulation of hippo signaling(GO:0035330)
2.9	5.8	GO:0061724	lipophagy(GO:0061724)
2.9	11.7	GO:0002326	B cell lineage commitment(GO:0002326)
2.9	8.7	GO:0061450	trophoblast cell migration(GO:0061450)
2.9	17.5	GO:0060687	regulation of branching involved in prostate gland morphogenesis(GO:0060687)
2.9	5.8	GO:0030421	defecation(GO:0030421)
2.9	43.2	GO:0060412	ventricular septum morphogenesis(GO:0060412)
2.9	8.6	GO:1903281	positive regulation of calcium:sodium antiporter activity(GO:1903281)
2.9	2.9	GO:0061198	fungiform papilla formation(GO:0061198)
2.9	22.9	GO:0015697	quaternary ammonium group transport(GO:0015697)
2.9	2.9	GO:0035552	oxidative single-stranded DNA demethylation(GO:0035552) RNA repair(GO:0042245)
2.9	34.3	GO:0007097	nuclear migration(GO:0007097)
2.8	8.5	GO:0000448	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
2.8	19.9	GO:0014857	regulation of skeletal muscle satellite cell proliferation(GO:0014842) regulation of skeletal muscle cell proliferation(GO:0014857)
2.8	8.5	GO:0055099	response to high density lipoprotein particle(GO:0055099)
2.8	11.3	GO:0007296	vitellogenesis(GO:0007296)
2.8	8.5	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
2.8	11.3	GO:2000035	regulation of stem cell division(GO:2000035)
2.8	2.8	GO:0014010	Schwann cell proliferation(GO:0014010)
2.8	36.4	GO:0045056	transcytosis(GO:0045056)
2.8	2.8	GO:0033864	positive regulation of NAD(P)H oxidase activity(GO:0033864)
2.8	2.8	GO:2000696	regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
2.8	11.1	GO:0045105	intermediate filament polymerization or depolymerization(GO:0045105)
2.8	72.1	GO:0000188	inactivation of MAPK activity(GO:0000188)
2.8	11.1	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
2.8	33.1	GO:0051014	actin filament severing(GO:0051014)
2.7	8.2	GO:0045054	constitutive secretory pathway(GO:0045054)
2.7	16.4	GO:0033622	integrin activation(GO:0033622)
2.7	10.9	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
2.7	35.4	GO:0000185	activation of MAPKKK activity(GO:0000185)
2.7	13.6	GO:0006983	ER overload response(GO:0006983)
2.7	16.3	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
2.7	5.4	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
2.7	10.8	GO:1990481	mRNA pseudouridine synthesis(GO:1990481)
2.7	5.4	GO:0061643	chemorepulsion of axon(GO:0061643)
2.7	21.6	GO:0050655	dermatan sulfate proteoglycan metabolic process(GO:0050655)
2.7	53.8	GO:0045663	positive regulation of myoblast differentiation(GO:0045663)
2.7	29.6	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
2.7	5.4	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
2.7	5.4	GO:0002488	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
2.7	10.7	GO:0061034	olfactory bulb mitral cell layer development(GO:0061034)
2.7	8.0	GO:1900147	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
2.7	2.7	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
2.6	2.6	GO:0034499	late endosome to Golgi transport(GO:0034499)
2.6	10.5	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
2.6	21.0	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
2.6	5.2	GO:0010986	regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
2.6	2.6	GO:0009188	ribonucleoside diphosphate biosynthetic process(GO:0009188)
2.6	13.1	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
2.6	20.9	GO:0019720	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
2.6	7.8	GO:0042732	D-xylose metabolic process(GO:0042732)
2.6	26.1	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
2.6	5.2	GO:0061152	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
2.6	5.2	GO:1904976	cellular response to bleomycin(GO:1904976)
2.6	5.2	GO:0032304	negative regulation of icosanoid secretion(GO:0032304)
2.6	7.8	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
2.6	15.5	GO:0060721	regulation of spongiotrophoblast cell proliferation(GO:0060721) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
2.6	10.3	GO:0051958	methotrexate transport(GO:0051958)
2.6	10.3	GO:1902732	positive regulation of chondrocyte proliferation(GO:1902732)
2.6	20.5	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
2.6	5.1	GO:0032417	positive regulation of sodium:proton antiporter activity(GO:0032417)
2.6	56.2	GO:0048333	mesodermal cell differentiation(GO:0048333)
2.5	5.0	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)
2.5	10.1	GO:0033210	leptin-mediated signaling pathway(GO:0033210)
2.5	5.0	GO:0097360	chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
2.5	24.9	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
2.5	10.0	GO:0032707	negative regulation of interleukin-23 production(GO:0032707)
2.5	14.9	GO:0002934	desmosome organization(GO:0002934)
2.5	19.8	GO:0048069	eye pigmentation(GO:0048069)
2.5	7.4	GO:1902167	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
2.5	9.9	GO:0006285	base-excision repair, AP site formation(GO:0006285)
2.5	9.8	GO:0014877	response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
2.5	9.8	GO:0006428	isoleucyl-tRNA aminoacylation(GO:0006428)
2.4	7.3	GO:0045918	negative regulation of cytolysis(GO:0045918)
2.4	12.2	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
2.4	24.4	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
2.4	26.5	GO:0046033	AMP metabolic process(GO:0046033)
2.4	7.2	GO:0009758	carbohydrate utilization(GO:0009758)
2.4	4.8	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
2.4	9.6	GO:1905235	carbohydrate export(GO:0033231) daunorubicin transport(GO:0043215) response to borneol(GO:1905230) cellular response to borneol(GO:1905231) response to codeine(GO:1905233) response to quercetin(GO:1905235) response to cyclosporin A(GO:1905237) drug transport across blood-brain barrier(GO:1990962) establishment of blood-retinal barrier(GO:1990963)
2.4	4.8	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
2.4	7.2	GO:0006178	purine ribonucleoside salvage(GO:0006166) guanine salvage(GO:0006178) purine nucleobase salvage(GO:0043096) GMP catabolic process(GO:0046038) guanine biosynthetic process(GO:0046099)
2.4	4.8	GO:0048560	establishment of anatomical structure orientation(GO:0048560)
2.4	7.2	GO:0006574	valine catabolic process(GO:0006574)
2.4	7.2	GO:0080120	CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
2.4	19.1	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
2.4	11.9	GO:0040023	establishment of nucleus localization(GO:0040023)
2.4	16.7	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
2.4	4.7	GO:1903630	regulation of aminoacyl-tRNA ligase activity(GO:1903630)
2.4	4.7	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
2.4	70.9	GO:0035987	endodermal cell differentiation(GO:0035987)
2.4	9.4	GO:0006014	D-ribose metabolic process(GO:0006014)
2.4	2.4	GO:0016561	protein import into peroxisome matrix, translocation(GO:0016561)
2.4	4.7	GO:0060754	positive regulation of mast cell chemotaxis(GO:0060754)
2.3	4.7	GO:0002554	serotonin secretion by platelet(GO:0002554)
2.3	35.0	GO:1901663	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
2.3	9.3	GO:0002538	arachidonic acid metabolite production involved in inflammatory response(GO:0002538)
2.3	32.6	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
2.3	4.6	GO:0060364	frontal suture morphogenesis(GO:0060364)
2.3	4.6	GO:1990792	response to glial cell derived neurotrophic factor(GO:1990790) cellular response to glial cell derived neurotrophic factor(GO:1990792)
2.3	18.3	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
2.3	20.6	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
2.3	6.8	GO:0046968	cytosol to ER transport(GO:0046967) peptide antigen transport(GO:0046968)
2.3	4.6	GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998)
2.3	2.3	GO:0051775	response to redox state(GO:0051775)
2.3	38.5	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
2.3	4.5	GO:0006552	leucine catabolic process(GO:0006552)
2.3	9.0	GO:0032919	spermine acetylation(GO:0032919)
2.3	6.8	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
2.3	15.8	GO:0098706	ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
2.2	6.7	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
2.2	6.7	GO:0072709	cellular response to sorbitol(GO:0072709)
2.2	33.7	GO:0097284	hepatocyte apoptotic process(GO:0097284)
2.2	6.7	GO:0071863	regulation of cell proliferation in bone marrow(GO:0071863) negative regulation of cell proliferation in bone marrow(GO:1903769)
2.2	6.7	GO:1900086	regulation of peptidyl-tyrosine autophosphorylation(GO:1900084) positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
2.2	60.4	GO:0007520	myoblast fusion(GO:0007520)
2.2	4.4	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
2.2	11.1	GO:0098795	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
2.2	8.8	GO:0051542	elastin biosynthetic process(GO:0051542)
2.2	46.3	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
2.2	8.8	GO:0002282	microglial cell activation involved in immune response(GO:0002282) necroptotic signaling pathway(GO:0097527)
2.2	17.6	GO:0008616	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
2.2	35.1	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
2.2	4.4	GO:1990823	response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
2.2	6.5	GO:0072734	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
2.2	32.7	GO:0048305	immunoglobulin secretion(GO:0048305)
2.2	13.0	GO:0006776	vitamin A metabolic process(GO:0006776)
2.2	10.8	GO:0006685	sphingomyelin catabolic process(GO:0006685)
2.2	6.5	GO:1904380	endoplasmic reticulum mannose trimming(GO:1904380)
2.2	8.6	GO:0040033	miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
2.2	12.9	GO:0015074	DNA integration(GO:0015074)
2.1	21.5	GO:0002467	germinal center formation(GO:0002467)
2.1	10.7	GO:0060347	heart trabecula formation(GO:0060347)
2.1	21.4	GO:0010044	response to aluminum ion(GO:0010044)
2.1	126.2	GO:0007229	integrin-mediated signaling pathway(GO:0007229)
2.1	6.4	GO:0044375	regulation of peroxisome size(GO:0044375)
2.1	21.3	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
2.1	2.1	GO:2001012	mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
2.1	4.3	GO:1903334	positive regulation of protein folding(GO:1903334)
2.1	6.4	GO:0006083	acetate metabolic process(GO:0006083) propionate metabolic process(GO:0019541)
2.1	21.1	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
2.1	6.3	GO:0010934	macrophage cytokine production(GO:0010934)
2.1	4.2	GO:0001757	somite specification(GO:0001757)
2.1	25.0	GO:0043252	sodium-independent organic anion transport(GO:0043252)
2.1	6.2	GO:0009092	homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346)
2.1	2.1	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
2.1	6.2	GO:0001866	NK T cell proliferation(GO:0001866)
2.1	4.1	GO:1990253	cellular response to leucine starvation(GO:1990253)
2.1	4.1	GO:0035672	oligopeptide transmembrane transport(GO:0035672)
2.1	28.8	GO:1902187	negative regulation of viral release from host cell(GO:1902187)
2.1	8.2	GO:1900246	positive regulation of RIG-I signaling pathway(GO:1900246)
2.0	16.4	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
2.0	6.1	GO:0003383	apical constriction(GO:0003383)
2.0	4.1	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
2.0	14.3	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
2.0	24.5	GO:0032780	negative regulation of ATPase activity(GO:0032780)
2.0	6.1	GO:0032074	negative regulation of nuclease activity(GO:0032074)
2.0	10.2	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
2.0	6.1	GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
2.0	24.0	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
2.0	14.0	GO:0044598	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
2.0	11.9	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
2.0	6.0	GO:0086053	AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
2.0	9.9	GO:0032463	negative regulation of protein homooligomerization(GO:0032463)
2.0	27.7	GO:0042415	norepinephrine metabolic process(GO:0042415)
2.0	4.0	GO:1903233	regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
2.0	5.9	GO:0035105	sterol regulatory element binding protein import into nucleus(GO:0035105) negative regulation of adipose tissue development(GO:1904178)
2.0	3.9	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
2.0	9.8	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
2.0	3.9	GO:0035932	mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of mineralocorticoid secretion(GO:2000855) positive regulation of mineralocorticoid secretion(GO:2000857) regulation of aldosterone secretion(GO:2000858) positive regulation of aldosterone secretion(GO:2000860)
1.9	5.8	GO:0036500	ATF6-mediated unfolded protein response(GO:0036500)
1.9	7.8	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
1.9	5.8	GO:0019064	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
1.9	5.8	GO:0060430	lung saccule development(GO:0060430)
1.9	27.1	GO:0070208	protein heterotrimerization(GO:0070208)
1.9	5.8	GO:0019087	transformation of host cell by virus(GO:0019087)
1.9	7.7	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
1.9	7.7	GO:2000609	regulation of thyroid hormone generation(GO:2000609)
1.9	9.6	GO:0071233	cellular response to leucine(GO:0071233)
1.9	5.7	GO:0033306	phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
1.9	32.3	GO:0050779	RNA destabilization(GO:0050779)
1.9	7.6	GO:0010896	regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
1.9	5.7	GO:0031204	posttranslational protein targeting to membrane, translocation(GO:0031204)
1.9	5.7	GO:0010133	proline catabolic process to glutamate(GO:0010133)
1.9	9.4	GO:0070235	regulation of activation-induced cell death of T cells(GO:0070235)
1.9	24.5	GO:0030574	collagen catabolic process(GO:0030574)
1.9	5.7	GO:0006004	fucose metabolic process(GO:0006004)
1.9	9.4	GO:0098902	regulation of membrane depolarization during action potential(GO:0098902)
1.9	18.7	GO:0032060	bleb assembly(GO:0032060)
1.9	104.4	GO:0006635	fatty acid beta-oxidation(GO:0006635)
1.9	14.9	GO:0030812	negative regulation of nucleotide catabolic process(GO:0030812)
1.9	16.7	GO:0019430	removal of superoxide radicals(GO:0019430)
1.9	16.7	GO:0060211	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
1.9	5.6	GO:0021699	cerebellar cortex maturation(GO:0021699)
1.9	29.6	GO:0010257	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
1.8	12.9	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
1.8	14.7	GO:0006670	sphingosine metabolic process(GO:0006670)
1.8	3.7	GO:0048619	embryonic hindgut morphogenesis(GO:0048619)
1.8	16.4	GO:0015886	heme transport(GO:0015886)
1.8	5.5	GO:0015770	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
1.8	3.6	GO:0060965	negative regulation of gene silencing by miRNA(GO:0060965)
1.8	3.6	GO:0046321	positive regulation of fatty acid oxidation(GO:0046321)
1.8	12.7	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
1.8	12.7	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
1.8	5.4	GO:0097051	establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
1.8	7.2	GO:0071284	cellular response to lead ion(GO:0071284)
1.8	1.8	GO:0006101	citrate metabolic process(GO:0006101)
1.8	26.9	GO:0097320	membrane tubulation(GO:0097320)
1.8	14.3	GO:2000052	positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
1.8	3.6	GO:2000345	regulation of hepatocyte proliferation(GO:2000345)
1.8	14.2	GO:0060033	anatomical structure regression(GO:0060033)
1.8	5.3	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
1.8	5.3	GO:0010999	regulation of eIF2 alpha phosphorylation by heme(GO:0010999)
1.8	33.3	GO:0010842	retina layer formation(GO:0010842)
1.8	5.3	GO:0048133	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
1.7	7.0	GO:0071955	recycling endosome to Golgi transport(GO:0071955)
1.7	5.2	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
1.7	5.2	GO:0045630	positive regulation of T-helper 2 cell differentiation(GO:0045630)
1.7	7.0	GO:0071409	cellular response to cycloheximide(GO:0071409)
1.7	5.2	GO:0032298	positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
1.7	5.2	GO:0039530	MDA-5 signaling pathway(GO:0039530)
1.7	12.1	GO:0043249	erythrocyte maturation(GO:0043249)
1.7	5.2	GO:2001016	positive regulation of skeletal muscle cell differentiation(GO:2001016)
1.7	12.1	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
1.7	5.2	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
1.7	3.4	GO:0046040	IMP metabolic process(GO:0046040)
1.7	6.9	GO:0061511	centriole elongation(GO:0061511)
1.7	10.3	GO:0044034	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
1.7	5.1	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
1.7	5.1	GO:0001765	membrane raft assembly(GO:0001765)
1.7	6.8	GO:0098734	macromolecule depalmitoylation(GO:0098734)
1.7	8.5	GO:0060075	regulation of resting membrane potential(GO:0060075)
1.7	5.1	GO:0072553	terminal button organization(GO:0072553)
1.7	5.1	GO:0090247	cell motility involved in somitogenic axis elongation(GO:0090247) regulation of cell motility involved in somitogenic axis elongation(GO:0090249)
1.7	6.8	GO:0016554	cytidine to uridine editing(GO:0016554)
1.7	5.1	GO:0010847	regulation of chromatin assembly(GO:0010847)
1.7	30.3	GO:0036075	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
1.7	10.1	GO:0045060	negative thymic T cell selection(GO:0045060)
1.7	3.4	GO:0007056	spindle assembly involved in female meiosis(GO:0007056)
1.7	8.4	GO:0042908	xenobiotic transport(GO:0042908)
1.7	1.7	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
1.7	11.7	GO:0048251	elastic fiber assembly(GO:0048251)
1.7	5.0	GO:0098501	polynucleotide dephosphorylation(GO:0098501) polynucleotide 5' dephosphorylation(GO:0098507)
1.7	10.0	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
1.7	6.6	GO:0046725	negative regulation of macrophage fusion(GO:0034240) negative regulation of syncytium formation by plasma membrane fusion(GO:0034242) negative regulation by virus of viral protein levels in host cell(GO:0046725)
1.7	16.6	GO:0016266	O-glycan processing(GO:0016266)
1.7	5.0	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
1.7	13.2	GO:1901977	negative regulation of cell cycle checkpoint(GO:1901977) negative regulation of DNA damage checkpoint(GO:2000002)
1.6	6.5	GO:0046338	phosphatidylethanolamine catabolic process(GO:0046338)
1.6	31.0	GO:0061462	protein localization to lysosome(GO:0061462)
1.6	39.1	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
1.6	14.6	GO:0035434	copper ion transmembrane transport(GO:0035434)
1.6	1.6	GO:0071163	DNA replication preinitiation complex assembly(GO:0071163)
1.6	9.7	GO:0060510	Type II pneumocyte differentiation(GO:0060510)
1.6	8.1	GO:0001302	replicative cell aging(GO:0001302)
1.6	6.5	GO:0070537	histone H2A K63-linked deubiquitination(GO:0070537)
1.6	1.6	GO:0098917	retrograde trans-synaptic signaling(GO:0098917)
1.6	8.1	GO:0045218	zonula adherens maintenance(GO:0045218)
1.6	8.0	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
1.6	1.6	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
1.6	6.4	GO:0002913	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
1.6	6.4	GO:0033184	positive regulation of histone ubiquitination(GO:0033184)
1.6	12.8	GO:0045351	type I interferon biosynthetic process(GO:0045351)
1.6	3.2	GO:0006431	methionyl-tRNA aminoacylation(GO:0006431)
1.6	7.9	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
1.6	11.1	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
1.6	11.1	GO:0042940	D-amino acid transport(GO:0042940)
1.6	9.5	GO:0002943	tRNA dihydrouridine synthesis(GO:0002943)
1.6	4.7	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
1.6	12.6	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
1.6	15.8	GO:0048485	sympathetic nervous system development(GO:0048485)
1.6	11.0	GO:0009235	cobalamin metabolic process(GO:0009235)
1.6	6.3	GO:0060178	regulation of exocyst localization(GO:0060178)
1.6	28.2	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
1.6	20.3	GO:0048753	melanosome organization(GO:0032438) pigment granule organization(GO:0048753)
1.6	7.8	GO:0086100	endothelin receptor signaling pathway(GO:0086100)
1.6	4.7	GO:0044778	meiotic DNA integrity checkpoint(GO:0044778)
1.5	9.3	GO:2000210	positive regulation of anoikis(GO:2000210)
1.5	13.9	GO:0017121	phospholipid scrambling(GO:0017121)
1.5	4.6	GO:0006011	UDP-glucose metabolic process(GO:0006011)
1.5	26.2	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
1.5	15.4	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
1.5	38.1	GO:0010761	fibroblast migration(GO:0010761)
1.5	7.6	GO:0035188	blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
1.5	3.0	GO:0043328	protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
1.5	4.6	GO:0032218	riboflavin transport(GO:0032218)
1.5	7.6	GO:0031443	fast-twitch skeletal muscle fiber contraction(GO:0031443)
1.5	13.6	GO:0071481	cellular response to X-ray(GO:0071481)
1.5	1.5	GO:0090024	negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
1.5	10.6	GO:0030643	cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
1.5	68.9	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
1.5	22.4	GO:0035855	megakaryocyte development(GO:0035855)
1.5	3.0	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
1.5	7.4	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
1.5	19.3	GO:0042407	cristae formation(GO:0042407)
1.5	3.0	GO:0033590	response to cobalamin(GO:0033590)
1.5	5.9	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
1.5	1.5	GO:0072176	nephric duct development(GO:0072176) nephric duct morphogenesis(GO:0072178)
1.5	10.2	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
1.5	31.9	GO:0060325	face morphogenesis(GO:0060325)
1.4	10.1	GO:0006884	cell volume homeostasis(GO:0006884)
1.4	28.9	GO:0019835	cytolysis(GO:0019835)
1.4	8.7	GO:0097210	response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
1.4	2.9	GO:0000101	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
1.4	5.7	GO:1902895	positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
1.4	21.3	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
1.4	8.5	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
1.4	4.3	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
1.4	4.3	GO:1902287	trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
1.4	7.1	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
1.4	14.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
1.4	11.3	GO:0071404	cellular response to low-density lipoprotein particle stimulus(GO:0071404)
1.4	7.0	GO:0006572	tyrosine catabolic process(GO:0006572)
1.4	7.0	GO:0006021	inositol biosynthetic process(GO:0006021)
1.4	7.0	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
1.4	2.8	GO:1904528	positive regulation of microtubule binding(GO:1904528)
1.4	8.4	GO:0040016	embryonic cleavage(GO:0040016)
1.4	4.2	GO:0006567	threonine catabolic process(GO:0006567)
1.4	11.2	GO:0001913	T cell mediated cytotoxicity(GO:0001913)
1.4	8.3	GO:0033129	positive regulation of histone phosphorylation(GO:0033129)
1.4	5.5	GO:0097676	histone H3-K36 dimethylation(GO:0097676)
1.4	2.8	GO:0080144	amino acid homeostasis(GO:0080144)
1.4	2.8	GO:0035089	establishment of apical/basal cell polarity(GO:0035089)
1.4	6.9	GO:2000586	regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586)
1.4	20.6	GO:0035269	protein O-linked mannosylation(GO:0035269)
1.4	8.2	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
1.4	2.7	GO:0034696	response to prostaglandin F(GO:0034696)
1.4	5.4	GO:0009822	alkaloid catabolic process(GO:0009822) isoquinoline alkaloid metabolic process(GO:0033076)
1.4	4.1	GO:0060339	negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
1.4	5.4	GO:1904177	regulation of adipose tissue development(GO:1904177)
1.4	1.4	GO:0035799	ureter maturation(GO:0035799)
1.3	2.7	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
1.3	9.4	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
1.3	12.1	GO:0034142	toll-like receptor 4 signaling pathway(GO:0034142)
1.3	1.3	GO:0032364	oxygen homeostasis(GO:0032364)
1.3	2.7	GO:0060297	regulation of sarcomere organization(GO:0060297)
1.3	6.6	GO:0060334	regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
1.3	4.0	GO:1903862	positive regulation of oxidative phosphorylation(GO:1903862)
1.3	7.9	GO:0015670	carbon dioxide transport(GO:0015670)
1.3	10.5	GO:0070234	positive regulation of T cell apoptotic process(GO:0070234)
1.3	9.2	GO:0039529	RIG-I signaling pathway(GO:0039529)
1.3	17.1	GO:0044381	glucose import in response to insulin stimulus(GO:0044381)
1.3	3.9	GO:1903413	cellular response to bile acid(GO:1903413)
1.3	11.8	GO:0042036	negative regulation of cytokine biosynthetic process(GO:0042036)
1.3	3.9	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
1.3	7.8	GO:0000050	urea cycle(GO:0000050)
1.3	3.9	GO:0018065	protein-cofactor linkage(GO:0018065)
1.3	5.2	GO:0035553	oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
1.3	3.9	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
1.3	2.6	GO:0006824	cobalt ion transport(GO:0006824)
1.3	9.0	GO:0060372	regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
1.3	9.0	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
1.3	5.2	GO:0034421	post-translational protein acetylation(GO:0034421)
1.3	95.0	GO:0090630	activation of GTPase activity(GO:0090630)
1.3	3.8	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
1.3	9.0	GO:0036119	response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
1.3	39.6	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
1.3	10.1	GO:0070474	positive regulation of uterine smooth muscle contraction(GO:0070474)
1.3	2.5	GO:0038031	non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
1.3	5.1	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
1.3	6.3	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
1.3	6.3	GO:0021785	branchiomotor neuron axon guidance(GO:0021785)
1.3	13.8	GO:0003159	morphogenesis of an endothelium(GO:0003159) endothelial tube morphogenesis(GO:0061154)
1.3	10.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
1.3	1.3	GO:0003207	cardiac chamber formation(GO:0003207)
1.3	12.5	GO:0030953	astral microtubule organization(GO:0030953)
1.3	6.3	GO:0036344	platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
1.2	2.5	GO:2001200	positive regulation of dendritic cell differentiation(GO:2001200)
1.2	14.9	GO:0032757	positive regulation of interleukin-8 production(GO:0032757)
1.2	12.3	GO:0035584	calcium-mediated signaling using intracellular calcium source(GO:0035584)
1.2	2.5	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
1.2	2.5	GO:0007262	STAT protein import into nucleus(GO:0007262)
1.2	7.4	GO:0007021	tubulin complex assembly(GO:0007021)
1.2	3.7	GO:0035928	rRNA import into mitochondrion(GO:0035928)
1.2	4.9	GO:0035457	cellular response to interferon-alpha(GO:0035457)
1.2	4.9	GO:0001773	myeloid dendritic cell activation(GO:0001773)
1.2	1.2	GO:0021539	subthalamus development(GO:0021539)
1.2	3.7	GO:1902606	regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
1.2	6.1	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
1.2	3.6	GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
1.2	2.4	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
1.2	36.0	GO:0043297	apical junction assembly(GO:0043297)
1.2	7.2	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
1.2	10.8	GO:0050832	defense response to fungus(GO:0050832)
1.2	5.9	GO:0006103	2-oxoglutarate metabolic process(GO:0006103)
1.2	14.3	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
1.2	15.4	GO:0015693	magnesium ion transport(GO:0015693)
1.2	2.4	GO:0002711	positive regulation of T cell mediated immunity(GO:0002711)
1.2	5.9	GO:0071280	cellular response to copper ion(GO:0071280)
1.2	22.4	GO:0006972	hyperosmotic response(GO:0006972)
1.2	2.4	GO:0009227	nucleotide-sugar catabolic process(GO:0009227)
1.2	3.5	GO:0038203	TORC2 signaling(GO:0038203)
1.2	15.3	GO:0071294	cellular response to zinc ion(GO:0071294)
1.2	11.7	GO:0010666	positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
1.2	11.7	GO:0006657	CDP-choline pathway(GO:0006657)
1.2	1.2	GO:1900275	negative regulation of phospholipase C activity(GO:1900275)
1.2	3.5	GO:0035728	response to hepatocyte growth factor(GO:0035728)
1.1	4.6	GO:0045624	positive regulation of T-helper cell differentiation(GO:0045624)
1.1	11.5	GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
1.1	18.3	GO:0046039	GTP metabolic process(GO:0046039)
1.1	3.4	GO:0034349	glial cell apoptotic process(GO:0034349)
1.1	12.5	GO:0019076	viral release from host cell(GO:0019076)
1.1	3.4	GO:0003050	regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
1.1	4.5	GO:0019934	cGMP-mediated signaling(GO:0019934)
1.1	4.5	GO:0071276	cellular response to cadmium ion(GO:0071276)
1.1	3.4	GO:0006801	superoxide metabolic process(GO:0006801)
1.1	3.4	GO:0035964	COPI-coated vesicle budding(GO:0035964)
1.1	13.5	GO:1901409	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
1.1	4.5	GO:0042045	epithelial fluid transport(GO:0042045)
1.1	13.5	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
1.1	2.2	GO:0090241	negative regulation of histone H4 acetylation(GO:0090241)
1.1	1.1	GO:0071699	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
1.1	3.3	GO:0030920	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
1.1	6.6	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
1.1	4.4	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
1.1	2.2	GO:0015746	citrate transport(GO:0015746)
1.1	3.3	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
1.1	7.7	GO:0045048	protein insertion into ER membrane(GO:0045048)
1.1	5.5	GO:0001582	detection of chemical stimulus involved in sensory perception of sweet taste(GO:0001582)
1.1	7.7	GO:0007252	I-kappaB phosphorylation(GO:0007252)
1.1	4.3	GO:0097039	protein linear polyubiquitination(GO:0097039)
1.1	18.4	GO:0006493	protein O-linked glycosylation(GO:0006493)
1.1	6.4	GO:0015732	prostaglandin transport(GO:0015732)
1.1	4.3	GO:0090234	regulation of kinetochore assembly(GO:0090234)
1.1	11.7	GO:0009635	response to herbicide(GO:0009635)
1.1	41.5	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
1.1	3.2	GO:0036089	cleavage furrow formation(GO:0036089)
1.1	6.3	GO:0060441	epithelial tube branching involved in lung morphogenesis(GO:0060441)
1.1	2.1	GO:0016078	tRNA catabolic process(GO:0016078)
1.0	4.2	GO:0044068	modulation by symbiont of host cellular process(GO:0044068)
1.0	3.1	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
1.0	6.3	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
1.0	12.5	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
1.0	11.4	GO:0071872	cellular response to epinephrine stimulus(GO:0071872)
1.0	28.0	GO:0015701	bicarbonate transport(GO:0015701)
1.0	6.2	GO:1901096	regulation of autophagosome maturation(GO:1901096)
1.0	1.0	GO:0032366	intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
1.0	12.3	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
1.0	7.1	GO:0000459	exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
1.0	1.0	GO:0036508	protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
1.0	2.0	GO:0007035	vacuolar acidification(GO:0007035)
1.0	2.0	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
1.0	3.0	GO:1904424	regulation of GTP binding(GO:1904424)
1.0	1.0	GO:1904354	negative regulation of telomere capping(GO:1904354)
1.0	3.0	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
1.0	2.0	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
1.0	10.0	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
1.0	2.0	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
1.0	4.0	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
1.0	16.7	GO:0060976	coronary vasculature development(GO:0060976)
1.0	14.7	GO:0008589	regulation of smoothened signaling pathway(GO:0008589)
1.0	2.0	GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
1.0	4.9	GO:0046477	glycosylceramide catabolic process(GO:0046477)
1.0	17.5	GO:2000378	negative regulation of reactive oxygen species metabolic process(GO:2000378)
1.0	1.9	GO:0030327	prenylated protein catabolic process(GO:0030327)
1.0	1.0	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
1.0	8.6	GO:2000772	regulation of cellular senescence(GO:2000772)
1.0	2.9	GO:0010727	negative regulation of hydrogen peroxide metabolic process(GO:0010727)
1.0	1.9	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
1.0	5.7	GO:0006689	ganglioside catabolic process(GO:0006689)
1.0	5.7	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.9	0.9	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.9	5.7	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.9	5.7	GO:0090385	phagosome-lysosome fusion(GO:0090385)
0.9	3.8	GO:0031937	positive regulation of chromatin silencing(GO:0031937)
0.9	12.2	GO:1901642	nucleoside transmembrane transport(GO:1901642)
0.9	1.9	GO:0060825	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.9	3.7	GO:0015691	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.9	26.1	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.9	2.8	GO:1903358	regulation of Golgi organization(GO:1903358)
0.9	3.7	GO:0071318	cellular response to ATP(GO:0071318)
0.9	1.9	GO:0072144	renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.9	5.6	GO:0098780	response to mitochondrial depolarisation(GO:0098780)
0.9	4.6	GO:0098543	detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
0.9	4.6	GO:0008343	adult feeding behavior(GO:0008343)
0.9	2.7	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.9	0.9	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.9	7.2	GO:0000012	single strand break repair(GO:0000012)
0.9	7.2	GO:0042574	retinal metabolic process(GO:0042574)
0.9	2.7	GO:0035909	aorta morphogenesis(GO:0035909)
0.9	9.8	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.9	4.5	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.9	2.7	GO:0071469	response to alkaline pH(GO:0010446) cellular response to alkaline pH(GO:0071469)
0.9	5.3	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.9	7.1	GO:0010043	response to zinc ion(GO:0010043)
0.9	9.7	GO:0006144	purine nucleobase metabolic process(GO:0006144)
0.9	7.9	GO:0001516	prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.9	4.4	GO:0071712	ER-associated misfolded protein catabolic process(GO:0071712)
0.9	2.6	GO:2000687	negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.9	0.9	GO:1990009	retinal cell apoptotic process(GO:1990009)
0.9	3.5	GO:0032494	response to peptidoglycan(GO:0032494)
0.9	7.8	GO:0009404	toxin metabolic process(GO:0009404)
0.9	6.9	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.9	11.2	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.8	8.5	GO:2000036	regulation of stem cell population maintenance(GO:2000036)
0.8	16.1	GO:0045332	phospholipid translocation(GO:0045332)
0.8	1.7	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.8	22.7	GO:0061035	regulation of cartilage development(GO:0061035)
0.8	5.9	GO:0051255	spindle midzone assembly(GO:0051255)
0.8	5.9	GO:0098885	modification of postsynaptic actin cytoskeleton(GO:0098885)
0.8	1.7	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.8	0.8	GO:0016094	polyprenol biosynthetic process(GO:0016094)
0.8	5.0	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.8	2.5	GO:0045903	positive regulation of translational fidelity(GO:0045903)
0.8	1.7	GO:0071926	endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.8	7.4	GO:0038094	Fc-gamma receptor signaling pathway(GO:0038094)
0.8	15.6	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.8	5.8	GO:0009146	purine nucleoside triphosphate catabolic process(GO:0009146)
0.8	5.7	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.8	5.7	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.8	12.2	GO:0006895	Golgi to endosome transport(GO:0006895)
0.8	4.9	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.8	5.7	GO:0035437	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.8	11.3	GO:0071711	basement membrane organization(GO:0071711)
0.8	10.5	GO:2000757	negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.8	4.8	GO:0001973	adenosine receptor signaling pathway(GO:0001973)
0.8	4.8	GO:0070257	positive regulation of mucus secretion(GO:0070257)
0.8	7.9	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.8	8.7	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
0.8	6.3	GO:0000920	cell separation after cytokinesis(GO:0000920)
0.8	2.4	GO:0010968	regulation of microtubule nucleation(GO:0010968)
0.8	9.5	GO:0006509	membrane protein ectodomain proteolysis(GO:0006509)
0.8	1.6	GO:0035904	aorta development(GO:0035904)
0.8	1.6	GO:0044539	long-chain fatty acid import(GO:0044539)
0.8	3.9	GO:0070314	G1 to G0 transition(GO:0070314)
0.8	5.5	GO:0009744	response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.8	3.9	GO:0097435	fibril organization(GO:0097435)
0.8	6.2	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.8	7.0	GO:0044065	regulation of respiratory system process(GO:0044065)
0.8	1.6	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.8	10.1	GO:0030728	ovulation(GO:0030728)
0.8	1.5	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.8	4.6	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.8	6.9	GO:0031507	heterochromatin assembly(GO:0031507)
0.8	2.3	GO:0071494	cellular response to UV-C(GO:0071494)
0.8	3.0	GO:0034552	respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.8	6.0	GO:0051974	negative regulation of telomerase activity(GO:0051974)
0.8	9.0	GO:0055069	zinc ion homeostasis(GO:0055069)
0.8	3.0	GO:0048102	autophagic cell death(GO:0048102)
0.7	6.7	GO:0071380	cellular response to prostaglandin E stimulus(GO:0071380)
0.7	3.0	GO:0032827	natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.7	5.9	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.7	2.9	GO:1990592	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.7	4.4	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.7	5.0	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.7	5.0	GO:0044110	growth involved in symbiotic interaction(GO:0044110) growth of symbiont involved in interaction with host(GO:0044116) growth of symbiont in host(GO:0044117)
0.7	9.3	GO:0009435	NAD biosynthetic process(GO:0009435)
0.7	5.0	GO:0060571	morphogenesis of an epithelial fold(GO:0060571)
0.7	7.1	GO:0070849	response to epidermal growth factor(GO:0070849)
0.7	5.0	GO:0001782	B cell homeostasis(GO:0001782)
0.7	23.4	GO:1900076	regulation of cellular response to insulin stimulus(GO:1900076)
0.7	3.5	GO:2000010	positive regulation of protein localization to cell surface(GO:2000010)
0.7	4.2	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.7	12.0	GO:0045214	sarcomere organization(GO:0045214)
0.7	7.0	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.7	21.1	GO:0043507	positive regulation of JUN kinase activity(GO:0043507)
0.7	2.8	GO:0033683	nucleotide-excision repair, DNA incision(GO:0033683)
0.7	2.8	GO:0006829	zinc II ion transport(GO:0006829)
0.7	12.4	GO:0006000	fructose metabolic process(GO:0006000)
0.7	3.4	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.7	4.1	GO:2000641	regulation of early endosome to late endosome transport(GO:2000641)
0.7	6.1	GO:1903779	regulation of cardiac conduction(GO:1903779)
0.7	1.4	GO:1900019	hyaluronan catabolic process(GO:0030214) regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.7	2.0	GO:1990022	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.7	2.0	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.7	5.4	GO:0006901	vesicle coating(GO:0006901)
0.7	7.4	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440)
0.7	5.4	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.7	2.0	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.7	4.7	GO:0046655	folic acid metabolic process(GO:0046655)
0.7	2.7	GO:1903300	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.7	25.1	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.7	4.0	GO:0035376	sterol import(GO:0035376) cholesterol import(GO:0070508)
0.7	0.7	GO:0071971	extracellular exosome assembly(GO:0071971) regulation of extracellular exosome assembly(GO:1903551)
0.7	35.5	GO:0022900	electron transport chain(GO:0022900)
0.7	21.0	GO:0018345	protein palmitoylation(GO:0018345)
0.7	22.3	GO:0048704	embryonic skeletal system morphogenesis(GO:0048704)
0.7	3.3	GO:1904401	cellular response to Thyroid stimulating hormone(GO:1904401)
0.7	20.2	GO:0018279	peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.7	2.6	GO:0060037	pharyngeal system development(GO:0060037)
0.6	5.2	GO:0097205	renal filtration(GO:0097205)
0.6	3.2	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.6	11.0	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.6	4.5	GO:0010259	multicellular organism aging(GO:0010259)
0.6	0.6	GO:0015965	diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.6	8.3	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.6	2.5	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.6	3.8	GO:0006903	vesicle targeting(GO:0006903)
0.6	0.6	GO:0034650	cortisol metabolic process(GO:0034650) cortisol biosynthetic process(GO:0034651)
0.6	12.6	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.6	21.2	GO:0006739	NADP metabolic process(GO:0006739)
0.6	5.0	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.6	2.5	GO:0006949	syncytium formation(GO:0006949)
0.6	2.5	GO:0042148	strand invasion(GO:0042148)
0.6	16.0	GO:0006506	GPI anchor biosynthetic process(GO:0006506)
0.6	15.9	GO:0010508	positive regulation of autophagy(GO:0010508)
0.6	4.2	GO:0034472	snRNA 3'-end processing(GO:0034472)
0.6	3.0	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.6	16.8	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.6	16.7	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.6	6.5	GO:0006828	manganese ion transport(GO:0006828)
0.6	7.1	GO:0097577	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.6	2.9	GO:0035459	cargo loading into vesicle(GO:0035459)
0.6	1.8	GO:0031627	telomeric loop formation(GO:0031627)
0.6	4.7	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.6	1.7	GO:2000668	dendritic cell apoptotic process(GO:0097048) regulation of dendritic cell apoptotic process(GO:2000668)
0.6	2.3	GO:0032025	response to cobalt ion(GO:0032025)
0.6	1.1	GO:0046112	nucleobase biosynthetic process(GO:0046112)
0.6	3.4	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.6	9.0	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.6	3.9	GO:0070327	thyroid hormone transport(GO:0070327)
0.5	12.5	GO:0061045	negative regulation of wound healing(GO:0061045)
0.5	2.7	GO:0060318	definitive erythrocyte differentiation(GO:0060318)
0.5	0.5	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.5	4.2	GO:0042119	neutrophil activation(GO:0042119)
0.5	1.6	GO:0032790	ribosome disassembly(GO:0032790)
0.5	3.1	GO:1900454	positive regulation of long term synaptic depression(GO:1900454)
0.5	1.5	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.5	2.5	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.5	2.5	GO:0070914	UV-damage excision repair(GO:0070914)
0.5	5.5	GO:0010830	regulation of myotube differentiation(GO:0010830)
0.5	8.3	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.5	5.4	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.5	2.9	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.5	5.8	GO:1901983	regulation of protein acetylation(GO:1901983)
0.5	1.9	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.5	3.8	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.5	5.7	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.5	1.4	GO:0070900	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.5	10.4	GO:0033120	positive regulation of RNA splicing(GO:0033120)
0.5	17.9	GO:0051092	positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.5	5.0	GO:0006084	acetyl-CoA metabolic process(GO:0006084)
0.5	0.9	GO:0071718	sodium-independent icosanoid transport(GO:0071718)
0.5	1.8	GO:0070266	necroptotic process(GO:0070266)
0.5	3.6	GO:0019068	virion assembly(GO:0019068)
0.4	2.7	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.4	3.1	GO:0071168	protein localization to chromatin(GO:0071168)
0.4	0.9	GO:1904222	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.4	0.9	GO:0071033	nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.4	3.5	GO:2000398	regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.4	1.3	GO:2000811	negative regulation of anoikis(GO:2000811)
0.4	0.9	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.4	11.1	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.4	6.4	GO:0048286	lung alveolus development(GO:0048286)
0.4	6.4	GO:0001756	somitogenesis(GO:0001756)
0.4	4.3	GO:0002441	histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.4	0.8	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.4	7.1	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.4	0.4	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.4	3.8	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.4	4.5	GO:0006662	glycerol ether metabolic process(GO:0006662)
0.4	2.0	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.4	0.4	GO:0090669	telomerase RNA stabilization(GO:0090669)
0.4	1.6	GO:1904428	negative regulation of tubulin deacetylation(GO:1904428)
0.4	0.8	GO:0045065	cytotoxic T cell differentiation(GO:0045065)
0.4	30.2	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)
0.4	3.5	GO:0006661	phosphatidylinositol biosynthetic process(GO:0006661)
0.4	2.0	GO:0050901	leukocyte tethering or rolling(GO:0050901)
0.4	2.7	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.4	7.7	GO:0048662	negative regulation of smooth muscle cell proliferation(GO:0048662)
0.4	4.9	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.4	0.7	GO:0045577	regulation of B cell differentiation(GO:0045577)
0.4	6.6	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.4	0.7	GO:0018312	peptidyl-serine ADP-ribosylation(GO:0018312)
0.4	1.1	GO:0097332	response to antipsychotic drug(GO:0097332)
0.4	1.4	GO:1902969	mitotic DNA replication(GO:1902969)
0.4	2.2	GO:0006069	ethanol oxidation(GO:0006069)
0.4	1.1	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.4	1.8	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.4	25.3	GO:1902600	hydrogen ion transmembrane transport(GO:1902600)
0.3	11.1	GO:0045638	negative regulation of myeloid cell differentiation(GO:0045638)
0.3	1.4	GO:0070933	histone H4 deacetylation(GO:0070933)
0.3	5.7	GO:0032011	ARF protein signal transduction(GO:0032011)
0.3	1.7	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
0.3	0.7	GO:2001032	regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.3	4.7	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.3	20.3	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.3	1.0	GO:1900038	negative regulation of cellular response to hypoxia(GO:1900038)
0.3	2.3	GO:0034982	mitochondrial protein processing(GO:0034982)
0.3	2.3	GO:0006596	polyamine biosynthetic process(GO:0006596)
0.3	1.9	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.3	2.3	GO:0061085	regulation of histone H3-K27 methylation(GO:0061085)
0.3	0.3	GO:0060547	negative regulation of necrotic cell death(GO:0060547)
0.3	1.5	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.3	2.1	GO:0001927	exocyst assembly(GO:0001927)
0.3	0.9	GO:1903960	negative regulation of anion channel activity(GO:0010360) negative regulation of anion transmembrane transport(GO:1903960)
0.3	1.2	GO:2000647	negative regulation of stem cell proliferation(GO:2000647)
0.3	2.0	GO:0042136	neurotransmitter biosynthetic process(GO:0042136)
0.3	12.4	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.3	3.9	GO:0006879	cellular iron ion homeostasis(GO:0006879)
0.3	0.6	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.3	23.1	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.3	2.6	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.3	0.8	GO:0055129	L-proline biosynthetic process(GO:0055129)
0.3	6.0	GO:0015804	neutral amino acid transport(GO:0015804)
0.3	3.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.3	2.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.3	0.8	GO:0046015	regulation of transcription by glucose(GO:0046015)
0.3	1.0	GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.2	1.2	GO:0042780	tRNA 3'-end processing(GO:0042780)
0.2	3.4	GO:0043248	proteasome assembly(GO:0043248)
0.2	4.1	GO:0001938	positive regulation of endothelial cell proliferation(GO:0001938)
0.2	0.9	GO:0006361	transcription initiation from RNA polymerase I promoter(GO:0006361)
0.2	4.4	GO:0001522	pseudouridine synthesis(GO:0001522)
0.2	1.6	GO:0007320	insemination(GO:0007320)
0.2	0.7	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.2	2.2	GO:0006783	heme biosynthetic process(GO:0006783)
0.2	1.3	GO:0016584	nucleosome positioning(GO:0016584)
0.2	0.4	GO:0046851	negative regulation of bone remodeling(GO:0046851)
0.2	6.0	GO:0000186	activation of MAPKK activity(GO:0000186)
0.2	4.9	GO:0051897	positive regulation of protein kinase B signaling(GO:0051897)
0.2	0.9	GO:0060177	regulation of angiotensin metabolic process(GO:0060177)
0.2	0.8	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.2	0.6	GO:0032202	telomere assembly(GO:0032202)
0.2	0.8	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.2	4.9	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.2	1.4	GO:0014002	astrocyte development(GO:0014002)
0.2	5.8	GO:0032543	mitochondrial translation(GO:0032543)
0.2	1.4	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.2	2.2	GO:0031952	regulation of protein autophosphorylation(GO:0031952)
0.2	1.5	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.2	2.3	GO:0031581	hemidesmosome assembly(GO:0031581)
0.2	4.0	GO:0045995	regulation of embryonic development(GO:0045995)
0.2	0.2	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.2	0.4	GO:0007418	ventral midline development(GO:0007418)
0.2	2.7	GO:0050688	regulation of defense response to virus(GO:0050688)
0.2	1.1	GO:0006265	DNA topological change(GO:0006265)
0.2	0.9	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.2	2.1	GO:0031167	rRNA methylation(GO:0031167)
0.2	0.4	GO:2000767	positive regulation of cytoplasmic translation(GO:2000767)
0.2	0.5	GO:0043649	dicarboxylic acid catabolic process(GO:0043649)
0.2	1.0	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.2	0.8	GO:0050915	sensory perception of sour taste(GO:0050915)
0.2	2.6	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.2	1.5	GO:0048332	mesoderm morphogenesis(GO:0048332)
0.2	0.8	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.2	6.3	GO:0006400	tRNA modification(GO:0006400)
0.1	0.7	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1	0.6	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.1	2.1	GO:0005978	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1	0.1	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.1	0.5	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1	1.5	GO:0006336	DNA replication-independent nucleosome assembly(GO:0006336)
0.1	0.5	GO:1902416	regulation of mRNA binding(GO:1902415) positive regulation of mRNA binding(GO:1902416)
0.1	1.6	GO:0097352	autophagosome maturation(GO:0097352)
0.1	8.5	GO:0030198	extracellular matrix organization(GO:0030198)
0.1	1.1	GO:0009268	response to pH(GO:0009268)
0.1	0.6	GO:0007000	nucleolus organization(GO:0007000)
0.1	0.3	GO:0097264	self proteolysis(GO:0097264)
0.1	0.4	GO:0046519	sphingoid metabolic process(GO:0046519)
0.1	0.7	GO:0034969	histone arginine methylation(GO:0034969)
0.1	0.2	GO:0034729	histone H3-K79 methylation(GO:0034729)
0.1	1.2	GO:0032755	positive regulation of interleukin-6 production(GO:0032755)
0.1	2.3	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.1	1.3	GO:0006855	drug transmembrane transport(GO:0006855)
0.1	1.6	GO:0019236	response to pheromone(GO:0019236)
0.1	0.2	GO:0031054	pre-miRNA processing(GO:0031054)
0.1	1.2	GO:0001510	RNA methylation(GO:0001510)
0.1	2.1	GO:0007041	lysosomal transport(GO:0007041)
0.1	1.1	GO:0007040	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1	2.0	GO:0006487	protein N-linked glycosylation(GO:0006487)
0.1	0.2	GO:0016246	RNA interference(GO:0016246)
0.1	0.2	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1	0.6	GO:0031424	keratinization(GO:0031424)
0.1	1.4	GO:0006730	one-carbon metabolic process(GO:0006730)
0.1	0.7	GO:0030193	regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.1	0.3	GO:0007007	inner mitochondrial membrane organization(GO:0007007)
0.1	0.3	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.1	GO:1900736	regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.0	0.4	GO:0097354	protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0	0.1	GO:0097327	response to antineoplastic agent(GO:0097327)
0.0	0.2	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0	0.1	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.3	GO:0006027	glycosaminoglycan catabolic process(GO:0006027)
0.0	0.1	GO:0031053	primary miRNA processing(GO:0031053)
0.0	0.6	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.0	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.2	GO:0033139	regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0	0.3	GO:0098781	ncRNA transcription(GO:0098781)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
14.6	43.9	GO:0071148	TEAD-1-YAP complex(GO:0071148)
13.7	54.8	GO:0043259	laminin-10 complex(GO:0043259)
13.5	67.7	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
13.5	40.4	GO:1990796	photoreceptor cell terminal bouton(GO:1990796)
12.3	36.9	GO:0034667	integrin alpha3-beta1 complex(GO:0034667)
12.3	49.0	GO:0005588	collagen type V trimer(GO:0005588)
9.8	49.1	GO:0061689	tricellular tight junction(GO:0061689)
9.4	37.7	GO:0044393	microspike(GO:0044393)
9.1	36.5	GO:0005593	FACIT collagen trimer(GO:0005593)
8.8	70.7	GO:0097443	sorting endosome(GO:0097443)
8.2	24.6	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
7.8	23.3	GO:0097232	lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
7.5	37.4	GO:0035976	AP1 complex(GO:0035976)
7.0	20.9	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
6.9	27.6	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
6.9	34.4	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
6.4	199.0	GO:0008305	integrin complex(GO:0008305)
6.4	38.3	GO:0097342	ripoptosome(GO:0097342)
6.3	31.7	GO:0044530	supraspliceosomal complex(GO:0044530)
6.3	19.0	GO:1990032	parallel fiber(GO:1990032)
5.9	23.6	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
5.8	92.8	GO:0042612	MHC class I protein complex(GO:0042612)
5.7	57.3	GO:0042587	glycogen granule(GO:0042587)
5.6	22.5	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
5.2	5.2	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
5.2	25.9	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
5.2	15.5	GO:0005960	glycine cleavage complex(GO:0005960)
5.2	51.5	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
5.0	60.5	GO:0016600	flotillin complex(GO:0016600)
5.0	45.3	GO:0016461	unconventional myosin complex(GO:0016461)
4.9	19.4	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
4.8	33.6	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
4.8	19.1	GO:0045240	dihydrolipoyl dehydrogenase complex(GO:0045240) oxoglutarate dehydrogenase complex(GO:0045252)
4.7	23.7	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
4.7	18.9	GO:0031904	endosome lumen(GO:0031904)
4.5	13.5	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
4.5	44.7	GO:0043020	NADPH oxidase complex(GO:0043020)
4.4	21.8	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
4.3	47.7	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
4.3	17.0	GO:0031088	platelet dense granule membrane(GO:0031088)
4.2	12.7	GO:0005745	m-AAA complex(GO:0005745)
4.2	37.9	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
4.2	16.7	GO:0045298	tubulin complex(GO:0045298)
4.2	12.5	GO:0005943	phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
4.1	16.3	GO:0000938	GARP complex(GO:0000938)
3.9	7.8	GO:0036488	CHOP-C/EBP complex(GO:0036488)
3.9	42.9	GO:0043219	lateral loop(GO:0043219)
3.9	11.6	GO:0005749	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) fumarate reductase complex(GO:0045283)
3.8	91.3	GO:0016327	apicolateral plasma membrane(GO:0016327)
3.5	27.9	GO:0098645	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
3.5	10.4	GO:0045242	mitochondrial isocitrate dehydrogenase complex (NAD+)(GO:0005962) isocitrate dehydrogenase complex (NAD+)(GO:0045242)
3.3	16.7	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
3.3	286.5	GO:0032432	actin filament bundle(GO:0032432)
3.3	10.0	GO:0031095	platelet dense tubular network membrane(GO:0031095)
3.3	39.9	GO:0044294	dendritic growth cone(GO:0044294)
3.3	32.9	GO:0032593	insulin-responsive compartment(GO:0032593)
3.3	16.4	GO:0033588	Elongator holoenzyme complex(GO:0033588)
3.2	9.7	GO:1902560	GMP reductase complex(GO:1902560)
3.2	25.4	GO:0000815	ESCRT III complex(GO:0000815)
3.2	9.5	GO:0036117	hyaluranon cable(GO:0036117)
3.1	34.0	GO:0005797	Golgi medial cisterna(GO:0005797)
3.1	9.2	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
3.0	24.1	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
3.0	3.0	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
3.0	5.9	GO:0097422	tubular endosome(GO:0097422)
2.9	2.9	GO:1990909	Wnt signalosome(GO:1990909)
2.9	50.0	GO:0031528	microvillus membrane(GO:0031528)
2.9	52.5	GO:0005614	interstitial matrix(GO:0005614)
2.9	5.8	GO:0005899	insulin receptor complex(GO:0005899)
2.9	5.7	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
2.8	2.8	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
2.8	2.8	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
2.8	11.0	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
2.7	19.2	GO:0001651	dense fibrillar component(GO:0001651)
2.7	10.7	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
2.7	2.7	GO:0000839	Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
2.6	18.4	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
2.6	21.0	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
2.6	18.3	GO:0045293	mRNA editing complex(GO:0045293)
2.6	49.5	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
2.6	30.7	GO:0042627	chylomicron(GO:0042627)
2.5	2.5	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
2.5	5.0	GO:0060205	cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
2.5	12.5	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
2.4	4.9	GO:0043511	inhibin complex(GO:0043511)
2.4	12.2	GO:0031085	BLOC-3 complex(GO:0031085)
2.4	16.6	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
2.3	13.9	GO:0005915	zonula adherens(GO:0005915)
2.3	4.6	GO:0071986	Ragulator complex(GO:0071986)
2.2	11.1	GO:0070195	growth hormone receptor complex(GO:0070195)
2.2	24.4	GO:0097208	alveolar lamellar body(GO:0097208)
2.2	10.8	GO:0090661	box H/ACA telomerase RNP complex(GO:0090661)
2.1	6.4	GO:0045180	basal cortex(GO:0045180)
2.1	17.1	GO:0031211	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
2.1	19.1	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
2.1	10.6	GO:0043293	apoptosome(GO:0043293)
2.1	16.7	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
2.1	8.3	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
2.0	20.5	GO:0005641	nuclear envelope lumen(GO:0005641)
2.0	4.1	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
2.0	48.8	GO:0000421	autophagosome membrane(GO:0000421)
2.0	8.1	GO:0060053	neurofilament cytoskeleton(GO:0060053)
2.0	8.0	GO:0005927	muscle tendon junction(GO:0005927)
2.0	8.0	GO:0045098	type III intermediate filament(GO:0045098)
2.0	86.0	GO:0060170	ciliary membrane(GO:0060170)
2.0	3.9	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
2.0	17.6	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
2.0	23.4	GO:0042641	actomyosin(GO:0042641)
1.9	25.3	GO:0005916	fascia adherens(GO:0005916)
1.9	9.7	GO:0097433	dense body(GO:0097433)
1.9	36.8	GO:0002102	podosome(GO:0002102)
1.9	17.4	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
1.9	26.7	GO:0005775	vacuolar lumen(GO:0005775)
1.9	30.2	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
1.9	7.5	GO:0097550	transcriptional preinitiation complex(GO:0097550)
1.9	3.7	GO:1990630	IRE1-RACK1-PP2A complex(GO:1990630)
1.9	111.9	GO:0005902	microvillus(GO:0005902)
1.9	11.1	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
1.9	152.1	GO:0031526	brush border membrane(GO:0031526)
1.9	33.4	GO:0042589	zymogen granule membrane(GO:0042589)
1.8	74.6	GO:0016328	lateral plasma membrane(GO:0016328)
1.8	5.5	GO:0032444	activin responsive factor complex(GO:0032444)
1.8	724.5	GO:0005924	cell-substrate adherens junction(GO:0005924)
1.8	23.2	GO:0044666	MLL3/4 complex(GO:0044666)
1.8	155.8	GO:0005604	basement membrane(GO:0005604)
1.8	3.5	GO:0031264	death-inducing signaling complex(GO:0031264)
1.7	8.7	GO:1990130	Iml1 complex(GO:1990130)
1.7	7.0	GO:0030121	AP-1 adaptor complex(GO:0030121)
1.7	5.2	GO:0097124	cyclin A2-CDK2 complex(GO:0097124)
1.7	3.4	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
1.7	5.0	GO:0044609	DBIRD complex(GO:0044609)
1.7	5.0	GO:0044232	organelle membrane contact site(GO:0044232)
1.7	5.0	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
1.7	8.4	GO:0097413	Lewy body(GO:0097413)
1.7	33.2	GO:0010369	chromocenter(GO:0010369)
1.6	17.9	GO:0035631	CD40 receptor complex(GO:0035631)
1.6	4.8	GO:0005687	U4 snRNP(GO:0005687)
1.6	12.6	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
1.6	26.8	GO:0019013	viral nucleocapsid(GO:0019013)
1.6	39.3	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
1.6	4.7	GO:0070522	ERCC4-ERCC1 complex(GO:0070522)
1.5	7.7	GO:0016342	catenin complex(GO:0016342)
1.5	10.7	GO:0061617	MICOS complex(GO:0061617)
1.5	3.0	GO:0000814	ESCRT II complex(GO:0000814)
1.5	34.1	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
1.5	10.4	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
1.5	7.3	GO:0032389	MutLalpha complex(GO:0032389)
1.5	5.9	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
1.4	8.7	GO:0034385	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
1.4	5.6	GO:0070765	gamma-secretase complex(GO:0070765)
1.4	5.5	GO:0032299	ribonuclease H2 complex(GO:0032299)
1.4	27.6	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
1.4	4.1	GO:0030666	endocytic vesicle membrane(GO:0030666)
1.4	10.9	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
1.3	4.0	GO:0032798	Swi5-Sfr1 complex(GO:0032798)
1.3	17.4	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
1.3	6.7	GO:0033093	Weibel-Palade body(GO:0033093)
1.3	82.7	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
1.3	6.6	GO:0070552	BRISC complex(GO:0070552)
1.3	11.9	GO:0000813	ESCRT I complex(GO:0000813)
1.3	4.0	GO:0090534	longitudinal sarcoplasmic reticulum(GO:0014801) calcium ion-transporting ATPase complex(GO:0090534)
1.3	14.4	GO:0032426	stereocilium tip(GO:0032426)
1.3	66.5	GO:0005913	cell-cell adherens junction(GO:0005913)
1.3	27.3	GO:0031305	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
1.3	70.8	GO:0032587	ruffle membrane(GO:0032587)
1.3	6.3	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
1.2	7.4	GO:0070847	core mediator complex(GO:0070847)
1.2	8.6	GO:0043657	host(GO:0018995) host cell(GO:0043657)
1.2	32.9	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
1.2	55.5	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
1.2	77.0	GO:0031970	mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
1.2	244.1	GO:0098852	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
1.2	8.4	GO:0097136	Bcl-2 family protein complex(GO:0097136)
1.2	52.6	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
1.2	4.8	GO:0042588	zymogen granule(GO:0042588)
1.2	416.9	GO:0031012	extracellular matrix(GO:0031012)
1.2	25.9	GO:0005685	U1 snRNP(GO:0005685)
1.2	23.6	GO:0055038	recycling endosome membrane(GO:0055038)
1.2	18.8	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
1.1	2.3	GO:1990590	ATF1-ATF4 transcription factor complex(GO:1990590)
1.1	14.8	GO:0005682	U5 snRNP(GO:0005682)
1.1	10.1	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
1.1	6.7	GO:0001940	male pronucleus(GO:0001940)
1.1	12.2	GO:0036038	MKS complex(GO:0036038)
1.1	370.9	GO:0005667	transcription factor complex(GO:0005667)
1.1	4.4	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
1.1	3.3	GO:0031415	NatA complex(GO:0031415)
1.1	60.5	GO:0000118	histone deacetylase complex(GO:0000118)
1.1	5.5	GO:1903768	sweet taste receptor complex(GO:1903767) taste receptor complex(GO:1903768)
1.1	5.5	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
1.1	1.1	GO:0034457	Mpp10 complex(GO:0034457)
1.1	262.7	GO:0005759	mitochondrial matrix(GO:0005759)
1.1	24.7	GO:0032588	trans-Golgi network membrane(GO:0032588)
1.1	11.6	GO:0072546	ER membrane protein complex(GO:0072546)
1.1	7.4	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
1.1	12.6	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
1.0	3.1	GO:0071942	XPC complex(GO:0071942)
1.0	6.2	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
1.0	2.1	GO:0005849	mRNA cleavage factor complex(GO:0005849)
1.0	9.3	GO:0005677	chromatin silencing complex(GO:0005677)
1.0	17.5	GO:0032420	stereocilium(GO:0032420)
1.0	4.1	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
1.0	4.1	GO:0036449	microtubule minus-end(GO:0036449)
1.0	5.0	GO:0016589	NURF complex(GO:0016589)
1.0	6.0	GO:0016012	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
1.0	5.0	GO:0032059	bleb(GO:0032059)
1.0	16.8	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
1.0	1.0	GO:0070820	tertiary granule(GO:0070820)
1.0	4.8	GO:0033270	paranode region of axon(GO:0033270)
1.0	9.5	GO:0031616	spindle pole centrosome(GO:0031616)
1.0	1.9	GO:1990023	mitotic spindle midzone(GO:1990023)
1.0	7.6	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
1.0	5.7	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.9	2.8	GO:1990879	CST complex(GO:1990879)
0.9	2.8	GO:0030478	actin cap(GO:0030478)
0.9	3.7	GO:0060091	kinocilium(GO:0060091)
0.9	4.7	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.9	1.9	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.9	12.9	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.9	229.2	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.9	10.9	GO:0017119	Golgi transport complex(GO:0017119)
0.9	12.3	GO:0016514	SWI/SNF complex(GO:0016514)
0.9	9.4	GO:0043218	compact myelin(GO:0043218)
0.9	10.2	GO:0070938	contractile ring(GO:0070938)
0.8	4.2	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.8	8.4	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.8	1.7	GO:0070578	RISC-loading complex(GO:0070578)
0.8	5.7	GO:0031091	platelet alpha granule(GO:0031091)
0.8	147.4	GO:0005764	lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.8	3.2	GO:0097196	Shu complex(GO:0097196)
0.8	55.9	GO:0030136	clathrin-coated vesicle(GO:0030136)
0.8	1.6	GO:0030914	STAGA complex(GO:0030914)
0.8	14.2	GO:0005922	connexon complex(GO:0005922)
0.8	9.4	GO:0005721	pericentric heterochromatin(GO:0005721)
0.8	4.7	GO:0030313	cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.8	6.1	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.8	4.6	GO:0042599	lamellar body(GO:0042599)
0.8	37.4	GO:0005776	autophagosome(GO:0005776)
0.8	64.3	GO:0030027	lamellipodium(GO:0030027)
0.8	3.8	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.7	23.2	GO:0005884	actin filament(GO:0005884)
0.7	6.0	GO:0034464	BBSome(GO:0034464)
0.7	6.6	GO:0043196	varicosity(GO:0043196)
0.7	3.6	GO:0000346	transcription export complex(GO:0000346)
0.7	6.4	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.7	213.1	GO:0016607	nuclear speck(GO:0016607)
0.7	5.6	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.7	4.1	GO:0005796	Golgi lumen(GO:0005796)
0.7	4.8	GO:0016272	prefoldin complex(GO:0016272)
0.7	8.8	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.7	4.0	GO:0031298	replication fork protection complex(GO:0031298)
0.7	2.6	GO:0005828	kinetochore microtubule(GO:0005828)
0.7	34.2	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.6	3.9	GO:0000798	nuclear cohesin complex(GO:0000798)
0.6	8.4	GO:0000788	nuclear nucleosome(GO:0000788)
0.6	1.3	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.6	25.8	GO:0044291	cell-cell contact zone(GO:0044291)
0.6	0.6	GO:0071203	WASH complex(GO:0071203)
0.6	3.2	GO:0005827	polar microtubule(GO:0005827)
0.6	12.0	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.6	3.8	GO:0035859	Seh1-associated complex(GO:0035859)
0.6	4.3	GO:0030991	intraciliary transport particle A(GO:0030991)
0.6	16.1	GO:0016459	myosin complex(GO:0016459)
0.6	1152.1	GO:0070062	extracellular exosome(GO:0070062)
0.6	1.2	GO:0034455	t-UTP complex(GO:0034455)
0.6	1.8	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.6	15.3	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.5	24.7	GO:0005811	lipid particle(GO:0005811)
0.5	4.2	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.5	40.9	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.5	4.2	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.5	5.7	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.5	5.7	GO:0001772	immunological synapse(GO:0001772)
0.5	17.2	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
0.5	1.9	GO:0031417	NatC complex(GO:0031417)
0.4	5.8	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.4	1.8	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.4	4.8	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.4	1.7	GO:0032021	NELF complex(GO:0032021)
0.4	0.9	GO:0000125	PCAF complex(GO:0000125)
0.4	7.1	GO:1990752	microtubule plus-end(GO:0035371) microtubule end(GO:1990752)
0.4	1.3	GO:0031074	nucleocytoplasmic shuttling complex(GO:0031074)
0.4	3.2	GO:0070161	anchoring junction(GO:0070161)
0.4	1.9	GO:0005642	annulate lamellae(GO:0005642)
0.4	26.1	GO:0043296	apical junction complex(GO:0043296)
0.4	1.4	GO:0048476	Holliday junction resolvase complex(GO:0048476)
0.3	2.7	GO:0005662	DNA replication factor A complex(GO:0005662)
0.3	0.7	GO:0070557	PCNA-p21 complex(GO:0070557)
0.3	2.6	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.3	1.3	GO:0033503	ubiquitin conjugating enzyme complex(GO:0031371) HULC complex(GO:0033503)
0.3	0.9	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.3	5.4	GO:0097546	ciliary base(GO:0097546)
0.3	0.6	GO:0031429	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.3	3.1	GO:0042555	MCM complex(GO:0042555)
0.3	2.2	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.3	2.2	GO:0031968	outer membrane(GO:0019867) organelle outer membrane(GO:0031968)
0.3	0.8	GO:0033263	CORVET complex(GO:0033263)
0.3	0.3	GO:0071001	U4/U6 snRNP(GO:0071001)
0.3	0.5	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.3	14.6	GO:0005911	cell-cell junction(GO:0005911)
0.3	2.0	GO:0031430	M band(GO:0031430)
0.3	6.6	GO:0016235	aggresome(GO:0016235)
0.3	1.0	GO:0044327	dendritic spine head(GO:0044327)
0.2	2.7	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.2	1.9	GO:0008385	IkappaB kinase complex(GO:0008385)
0.2	1.7	GO:0044295	axonal growth cone(GO:0044295)
0.2	0.5	GO:0031680	G-protein beta/gamma-subunit complex(GO:0031680)
0.2	2.9	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.2	0.4	GO:0005896	interleukin-6 receptor complex(GO:0005896) ciliary neurotrophic factor receptor complex(GO:0070110)
0.2	0.4	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.2	3.0	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.2	0.2	GO:0098798	mitochondrial protein complex(GO:0098798)
0.2	0.5	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.2	0.5	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.2	2.3	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.2	6.5	GO:0045095	keratin filament(GO:0045095)
0.2	2.6	GO:0005801	cis-Golgi network(GO:0005801)
0.2	7.4	GO:0055037	recycling endosome(GO:0055037)
0.1	1.6	GO:0005905	clathrin-coated pit(GO:0005905)
0.1	3.6	GO:0001726	ruffle(GO:0001726)
0.1	0.3	GO:0032592	integral component of mitochondrial membrane(GO:0032592)
0.1	99.3	GO:0005739	mitochondrion(GO:0005739)
0.1	0.2	GO:0089701	U2AF(GO:0089701)
0.1	0.3	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1	0.4	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.1	0.5	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1	0.8	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.1	0.7	GO:0005903	brush border(GO:0005903)
0.1	4.1	GO:0030496	midbody(GO:0030496)
0.1	141.4	GO:0005829	cytosol(GO:0005829)
0.1	0.1	GO:0030689	Noc complex(GO:0030689)
0.1	1.8	GO:0031225	anchored component of membrane(GO:0031225)
0.1	1.0	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.1	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0	1.0	GO:0016323	basolateral plasma membrane(GO:0016323)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
22.1	66.2	GO:0033823	procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
19.5	97.7	GO:0038132	neuregulin binding(GO:0038132)
17.8	53.3	GO:0004046	aminoacylase activity(GO:0004046)
16.9	118.3	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
14.3	42.9	GO:0016403	dimethylargininase activity(GO:0016403)
13.1	104.5	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
13.0	104.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
12.0	155.9	GO:0048407	platelet-derived growth factor binding(GO:0048407)
11.7	35.0	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
9.5	47.4	GO:0001042	RNA polymerase I core binding(GO:0001042)
9.1	27.2	GO:0015141	succinate transmembrane transporter activity(GO:0015141)
9.0	27.1	GO:0070698	type I activin receptor binding(GO:0070698)
9.0	27.0	GO:0070506	high-density lipoprotein particle receptor activity(GO:0070506)
9.0	44.9	GO:0015220	choline transmembrane transporter activity(GO:0015220)
9.0	26.9	GO:0051538	3 iron, 4 sulfur cluster binding(GO:0051538)
8.9	35.6	GO:0030984	kininogen binding(GO:0030984)
8.9	26.7	GO:0004874	aryl hydrocarbon receptor activity(GO:0004874)
8.8	78.8	GO:0031994	insulin-like growth factor I binding(GO:0031994)
8.6	34.6	GO:0070644	vitamin D response element binding(GO:0070644)
8.6	25.9	GO:0004566	beta-glucuronidase activity(GO:0004566)
8.5	144.7	GO:0042813	Wnt-activated receptor activity(GO:0042813)
8.1	24.4	GO:2001070	starch binding(GO:2001070)
7.9	23.6	GO:0042895	antibiotic transporter activity(GO:0042895)
7.8	7.8	GO:0031995	insulin-like growth factor II binding(GO:0031995)
7.7	30.7	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
7.5	22.5	GO:0008405	arachidonic acid 11,12-epoxygenase activity(GO:0008405)
7.5	22.4	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
7.1	21.4	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
7.1	28.6	GO:0008670	2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
7.1	28.5	GO:0097108	hedgehog family protein binding(GO:0097108)
7.1	21.2	GO:0034186	apolipoprotein A-I binding(GO:0034186)
7.0	49.2	GO:0016018	cyclosporin A binding(GO:0016018)
6.8	27.3	GO:0035614	snRNA stem-loop binding(GO:0035614)
6.8	6.8	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
6.7	20.1	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
6.5	39.2	GO:0003840	gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
6.5	52.0	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
6.5	38.9	GO:0042954	lipoprotein transporter activity(GO:0042954)
6.4	64.2	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
6.4	19.3	GO:0004020	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
6.4	57.7	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
6.3	82.5	GO:0017147	Wnt-protein binding(GO:0017147)
6.3	37.9	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
6.2	24.8	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
6.2	18.6	GO:1902379	chemoattractant activity involved in axon guidance(GO:1902379)
6.2	18.5	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
6.2	43.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
6.0	18.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
6.0	35.8	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
6.0	23.9	GO:0048408	epidermal growth factor binding(GO:0048408)
6.0	23.8	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
5.9	23.7	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
5.8	23.4	GO:0002058	uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061)
5.8	40.8	GO:0030881	beta-2-microglobulin binding(GO:0030881)
5.7	85.8	GO:0005520	insulin-like growth factor binding(GO:0005520)
5.7	137.0	GO:0050431	transforming growth factor beta binding(GO:0050431)
5.6	22.4	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
5.6	16.7	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
5.5	5.5	GO:0070538	oleic acid binding(GO:0070538)
5.5	33.2	GO:0008420	CTD phosphatase activity(GO:0008420)
5.5	60.0	GO:0016783	sulfurtransferase activity(GO:0016783)
5.2	15.7	GO:0005333	norepinephrine transmembrane transporter activity(GO:0005333)
5.2	15.5	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
5.1	10.3	GO:0004096	catalase activity(GO:0004096)
5.1	25.6	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
5.1	20.2	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
5.1	40.4	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
5.0	20.1	GO:0016212	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
5.0	15.0	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
5.0	15.0	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
4.9	49.0	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
4.9	19.4	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
4.8	19.4	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
4.8	14.3	GO:0031177	phosphopantetheine binding(GO:0031177)
4.7	42.1	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
4.7	14.0	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
4.7	23.3	GO:0004301	epoxide hydrolase activity(GO:0004301)
4.7	14.0	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
4.6	13.7	GO:0004478	methionine adenosyltransferase activity(GO:0004478)
4.5	18.1	GO:0001156	TFIIIC-class transcription factor binding(GO:0001156)
4.5	36.1	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
4.5	67.1	GO:0015026	coreceptor activity(GO:0015026)
4.4	48.8	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
4.4	17.6	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
4.4	17.6	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
4.3	13.0	GO:0070053	thrombospondin receptor activity(GO:0070053)
4.3	17.3	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
4.3	17.2	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
4.3	17.2	GO:1990254	keratin filament binding(GO:1990254)
4.3	25.8	GO:0070728	leucine binding(GO:0070728)
4.3	106.8	GO:0046965	retinoid X receptor binding(GO:0046965)
4.3	29.8	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
4.2	25.5	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
4.2	12.6	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
4.2	54.5	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
4.1	4.1	GO:0070976	TIR domain binding(GO:0070976)
4.1	29.0	GO:0004064	arylesterase activity(GO:0004064)
4.1	8.2	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
4.1	8.2	GO:0015215	nucleotide transmembrane transporter activity(GO:0015215)
4.1	16.4	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
4.1	12.3	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
4.1	16.3	GO:0003696	satellite DNA binding(GO:0003696)
4.0	11.9	GO:0034211	GTP-dependent protein kinase activity(GO:0034211)
4.0	7.9	GO:0008177	succinate dehydrogenase (ubiquinone) activity(GO:0008177)
4.0	31.7	GO:0046790	virion binding(GO:0046790)
4.0	138.6	GO:0043236	laminin binding(GO:0043236)
4.0	15.8	GO:0008940	nitrate reductase activity(GO:0008940)
3.9	19.6	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
3.9	15.5	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
3.9	19.3	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
3.8	15.4	GO:0000293	ferric-chelate reductase activity(GO:0000293)
3.8	7.6	GO:0032564	dATP binding(GO:0032564)
3.8	45.3	GO:0008046	axon guidance receptor activity(GO:0008046)
3.8	11.3	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
3.8	67.8	GO:0044548	S100 protein binding(GO:0044548)
3.8	26.4	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
3.8	67.8	GO:0031005	filamin binding(GO:0031005)
3.8	11.3	GO:0016748	succinyltransferase activity(GO:0016748)
3.7	14.8	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
3.7	11.0	GO:0016015	morphogen activity(GO:0016015)
3.7	33.0	GO:0034056	estrogen response element binding(GO:0034056)
3.6	10.9	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
3.6	14.4	GO:0048039	ubiquinone binding(GO:0048039)
3.6	50.1	GO:0030898	actin-dependent ATPase activity(GO:0030898)
3.6	10.7	GO:0043398	HLH domain binding(GO:0043398)
3.5	10.6	GO:0034437	glycoprotein transporter activity(GO:0034437)
3.5	14.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
3.5	6.9	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
3.5	13.9	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
3.5	10.4	GO:0015229	L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
3.4	10.3	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
3.4	13.7	GO:0099609	microtubule lateral binding(GO:0099609)
3.4	27.3	GO:0004565	beta-galactosidase activity(GO:0004565)
3.4	17.1	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
3.4	10.2	GO:0047134	protein-disulfide reductase activity(GO:0047134)
3.4	6.8	GO:0015197	peptide transporter activity(GO:0015197)
3.4	23.8	GO:0035033	histone deacetylase regulator activity(GO:0035033)
3.4	10.2	GO:0000253	3-keto sterol reductase activity(GO:0000253)
3.4	27.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
3.4	20.2	GO:0046978	TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
3.4	20.1	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
3.3	16.7	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
3.3	40.0	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
3.3	13.3	GO:0071532	ankyrin repeat binding(GO:0071532)
3.3	19.8	GO:0035473	lipase binding(GO:0035473)
3.3	9.9	GO:0004370	glycerol kinase activity(GO:0004370)
3.3	19.7	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
3.3	13.1	GO:0008265	Mo-molybdopterin cofactor sulfurase activity(GO:0008265)
3.3	78.2	GO:0050840	extracellular matrix binding(GO:0050840)
3.2	19.4	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
3.2	9.7	GO:0016657	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
3.2	9.7	GO:0032427	GBD domain binding(GO:0032427)
3.2	35.4	GO:0070513	death domain binding(GO:0070513)
3.2	44.8	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
3.2	25.4	GO:0008172	S-methyltransferase activity(GO:0008172)
3.2	41.3	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
3.2	15.8	GO:0008823	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
3.1	9.4	GO:0030977	taurine binding(GO:0030977)
3.1	18.8	GO:0017040	ceramidase activity(GO:0017040)
3.1	9.3	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
3.1	15.4	GO:0004614	phosphoglucomutase activity(GO:0004614)
3.1	12.2	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
3.1	24.4	GO:0035197	siRNA binding(GO:0035197)
3.1	18.3	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
3.0	6.1	GO:0052743	inositol tetrakisphosphate phosphatase activity(GO:0052743)
3.0	66.6	GO:0001223	transcription coactivator binding(GO:0001223)
3.0	18.2	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
3.0	15.1	GO:0008503	benzodiazepine receptor activity(GO:0008503)
3.0	9.0	GO:0019809	spermidine binding(GO:0019809)
3.0	9.0	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
3.0	21.0	GO:0004957	prostaglandin E receptor activity(GO:0004957)
3.0	35.8	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
3.0	53.7	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
2.9	26.5	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
2.9	26.0	GO:0022833	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
2.8	5.7	GO:0042806	fucose binding(GO:0042806)
2.8	14.1	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
2.8	72.5	GO:0071837	HMG box domain binding(GO:0071837)
2.8	11.1	GO:0004903	growth hormone receptor activity(GO:0004903)
2.8	63.9	GO:0008157	protein phosphatase 1 binding(GO:0008157)
2.8	16.6	GO:0005113	patched binding(GO:0005113)
2.7	21.9	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
2.7	29.9	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
2.7	16.3	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
2.7	27.1	GO:0045295	gamma-catenin binding(GO:0045295)
2.7	2.7	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
2.7	13.5	GO:0070097	delta-catenin binding(GO:0070097)
2.7	18.7	GO:1990239	steroid hormone binding(GO:1990239)
2.6	21.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
2.6	105.0	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
2.6	10.5	GO:0050682	AF-2 domain binding(GO:0050682)
2.6	10.3	GO:0045159	myosin II binding(GO:0045159)
2.6	10.3	GO:0015350	methotrexate transporter activity(GO:0015350)
2.5	25.1	GO:0051959	dynein light intermediate chain binding(GO:0051959)
2.5	35.1	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
2.5	12.4	GO:0050501	hyaluronan synthase activity(GO:0050501)
2.5	19.9	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
2.5	9.9	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
2.5	9.8	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
2.5	63.9	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
2.5	12.3	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
2.5	9.8	GO:0004822	isoleucine-tRNA ligase activity(GO:0004822)
2.4	7.3	GO:0004948	adrenomedullin receptor activity(GO:0001605) calcitonin receptor activity(GO:0004948)
2.4	12.2	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
2.4	36.5	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
2.4	11.9	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
2.4	23.8	GO:0008432	JUN kinase binding(GO:0008432)
2.4	19.0	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
2.4	14.3	GO:0070411	I-SMAD binding(GO:0070411)
2.4	7.1	GO:0045322	unmethylated CpG binding(GO:0045322)
2.4	14.1	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
2.3	11.7	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
2.3	4.7	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
2.3	27.9	GO:0019911	structural constituent of myelin sheath(GO:0019911)
2.3	55.5	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
2.3	6.9	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
2.3	25.2	GO:0004017	adenylate kinase activity(GO:0004017)
2.3	16.0	GO:1990226	histone methyltransferase binding(GO:1990226)
2.3	27.2	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
2.3	6.8	GO:0008384	IkappaB kinase activity(GO:0008384)
2.2	4.5	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
2.2	17.8	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
2.2	6.7	GO:0031871	proteinase activated receptor binding(GO:0031871)
2.2	15.6	GO:0045545	syndecan binding(GO:0045545)
2.2	8.9	GO:0042608	T cell receptor binding(GO:0042608)
2.2	11.1	GO:0050816	phosphothreonine binding(GO:0050816)
2.2	28.7	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
2.2	6.6	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
2.2	11.0	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
2.2	19.7	GO:0045294	alpha-catenin binding(GO:0045294)
2.2	6.5	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
2.2	39.2	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
2.2	4.3	GO:0000982	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
2.2	15.2	GO:0043560	insulin receptor substrate binding(GO:0043560)
2.2	10.8	GO:0004920	interleukin-10 receptor activity(GO:0004920)
2.2	15.1	GO:0070569	uridylyltransferase activity(GO:0070569)
2.2	15.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
2.1	12.8	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
2.1	59.5	GO:0005452	inorganic anion exchanger activity(GO:0005452)
2.1	8.5	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
2.1	42.3	GO:0046875	ephrin receptor binding(GO:0046875)
2.1	35.7	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
2.1	35.7	GO:0017166	vinculin binding(GO:0017166)
2.1	4.2	GO:0004793	threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
2.1	45.9	GO:0071889	14-3-3 protein binding(GO:0071889)
2.1	6.3	GO:0001069	regulatory region RNA binding(GO:0001069)
2.1	33.3	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
2.1	4.1	GO:0005427	proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322) oligopeptide transmembrane transporter activity(GO:0035673)
2.1	16.4	GO:0015232	heme transporter activity(GO:0015232)
2.1	34.9	GO:0031996	thioesterase binding(GO:0031996)
2.0	16.3	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
2.0	40.5	GO:0004806	triglyceride lipase activity(GO:0004806)
2.0	52.2	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
2.0	8.0	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
2.0	18.0	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
2.0	14.0	GO:0048406	nerve growth factor binding(GO:0048406)
2.0	79.9	GO:0005044	scavenger receptor activity(GO:0005044)
2.0	25.9	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
2.0	19.9	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
2.0	6.0	GO:1903763	gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077) gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
2.0	7.9	GO:0003987	acetate-CoA ligase activity(GO:0003987)
2.0	13.9	GO:0004111	creatine kinase activity(GO:0004111)
2.0	5.9	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
2.0	33.4	GO:0017134	fibroblast growth factor binding(GO:0017134)
2.0	3.9	GO:0070699	type II activin receptor binding(GO:0070699)
2.0	7.8	GO:0031432	titin binding(GO:0031432)
2.0	13.7	GO:0043495	protein anchor(GO:0043495)
1.9	17.5	GO:0042285	xylosyltransferase activity(GO:0042285)
1.9	7.7	GO:0008140	cAMP response element binding protein binding(GO:0008140)
1.9	5.8	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
1.9	5.7	GO:0035497	cAMP response element binding(GO:0035497)
1.9	15.1	GO:0030957	Tat protein binding(GO:0030957)
1.9	5.7	GO:0004657	proline dehydrogenase activity(GO:0004657)
1.9	9.3	GO:0050786	RAGE receptor binding(GO:0050786)
1.9	5.6	GO:0004774	succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775)
1.8	9.2	GO:0008242	omega peptidase activity(GO:0008242)
1.8	7.4	GO:0055100	adiponectin binding(GO:0055100)
1.8	9.2	GO:0046923	ER retention sequence binding(GO:0046923)
1.8	3.7	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
1.8	16.6	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
1.8	11.0	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
1.8	5.5	GO:0015157	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
1.8	5.5	GO:0004852	uroporphyrinogen-III synthase activity(GO:0004852)
1.8	14.5	GO:0071253	connexin binding(GO:0071253)
1.8	14.3	GO:0001055	RNA polymerase II activity(GO:0001055)
1.8	7.1	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
1.8	3.6	GO:0042015	interleukin-20 binding(GO:0042015)
1.8	7.0	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
1.7	5.2	GO:0004335	galactokinase activity(GO:0004335)
1.7	8.7	GO:1990715	mRNA CDS binding(GO:1990715)
1.7	133.8	GO:0005178	integrin binding(GO:0005178)
1.7	8.7	GO:0034597	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
1.7	19.1	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
1.7	5.2	GO:0071933	Arp2/3 complex binding(GO:0071933)
1.7	29.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
1.7	13.7	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
1.7	6.8	GO:0034235	GPI anchor binding(GO:0034235)
1.7	18.7	GO:0004089	carbonate dehydratase activity(GO:0004089)
1.7	11.9	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
1.7	5.0	GO:0004651	polynucleotide 5'-phosphatase activity(GO:0004651)
1.7	18.3	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
1.7	8.3	GO:0004708	MAP kinase kinase activity(GO:0004708)
1.7	5.0	GO:0050145	uridylate kinase activity(GO:0009041) nucleoside phosphate kinase activity(GO:0050145)
1.7	5.0	GO:0055077	gap junction hemi-channel activity(GO:0055077)
1.6	17.9	GO:0070492	oligosaccharide binding(GO:0070492)
1.6	11.4	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
1.6	11.3	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
1.6	14.5	GO:0042609	CD4 receptor binding(GO:0042609)
1.6	24.0	GO:0008301	DNA binding, bending(GO:0008301)
1.6	4.8	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
1.6	9.5	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
1.6	17.2	GO:0050998	nitric-oxide synthase binding(GO:0050998)
1.6	7.8	GO:0004962	endothelin receptor activity(GO:0004962)
1.6	46.7	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
1.5	3.1	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
1.5	32.4	GO:0016881	acid-amino acid ligase activity(GO:0016881)
1.5	104.6	GO:0008013	beta-catenin binding(GO:0008013)
1.5	4.6	GO:0004832	valine-tRNA ligase activity(GO:0004832)
1.5	20.0	GO:0016805	dipeptidase activity(GO:0016805)
1.5	62.3	GO:0004879	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
1.5	4.6	GO:0032217	riboflavin transporter activity(GO:0032217)
1.5	6.1	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
1.5	4.5	GO:0004655	porphobilinogen synthase activity(GO:0004655)
1.5	22.6	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
1.5	5.9	GO:0036132	13-prostaglandin reductase activity(GO:0036132)
1.5	4.4	GO:0016882	cyclo-ligase activity(GO:0016882)
1.5	26.4	GO:0001530	lipopolysaccharide binding(GO:0001530)
1.4	5.8	GO:0004594	pantothenate kinase activity(GO:0004594)
1.4	8.6	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
1.4	8.6	GO:0030346	protein phosphatase 2B binding(GO:0030346)
1.4	8.6	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
1.4	39.5	GO:0050699	WW domain binding(GO:0050699)
1.4	4.2	GO:0030350	iron-responsive element binding(GO:0030350)
1.4	5.6	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
1.4	8.4	GO:0086059	voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
1.4	7.0	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
1.4	15.3	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
1.4	11.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
1.4	70.5	GO:0005201	extracellular matrix structural constituent(GO:0005201)
1.4	15.2	GO:0070567	cytidylyltransferase activity(GO:0070567)
1.4	5.5	GO:0003842	1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
1.4	8.2	GO:0005243	gap junction channel activity(GO:0005243)
1.4	4.1	GO:1901612	cardiolipin binding(GO:1901612)
1.4	5.4	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
1.3	116.9	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
1.3	5.4	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
1.3	4.0	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
1.3	4.0	GO:0016429	tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
1.3	30.6	GO:0035326	enhancer binding(GO:0035326)
1.3	5.3	GO:0036122	BMP binding(GO:0036122)
1.3	5.3	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
1.3	14.6	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
1.3	36.9	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
1.3	10.5	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
1.3	5.3	GO:0051731	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
1.3	5.3	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
1.3	7.9	GO:0034452	dynactin binding(GO:0034452)
1.3	128.2	GO:0017124	SH3 domain binding(GO:0017124)
1.3	11.7	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
1.3	6.5	GO:1990932	5.8S rRNA binding(GO:1990932)
1.3	5.2	GO:0035515	oxidative RNA demethylase activity(GO:0035515)
1.3	13.0	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
1.3	3.9	GO:0005329	dopamine transmembrane transporter activity(GO:0005329)
1.3	5.1	GO:1904288	BAT3 complex binding(GO:1904288)
1.3	34.6	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
1.3	17.7	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
1.3	7.6	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
1.3	45.3	GO:0008307	structural constituent of muscle(GO:0008307)
1.3	10.0	GO:0051400	BH domain binding(GO:0051400)
1.3	10.0	GO:0008131	primary amine oxidase activity(GO:0008131)
1.2	23.7	GO:0008199	ferric iron binding(GO:0008199)
1.2	14.9	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
1.2	32.3	GO:0043425	bHLH transcription factor binding(GO:0043425)
1.2	2.5	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
1.2	4.9	GO:0004487	methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
1.2	12.3	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
1.2	6.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
1.2	3.7	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
1.2	2.4	GO:1990459	transferrin receptor binding(GO:1990459)
1.2	30.6	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
1.2	6.1	GO:0001054	RNA polymerase I activity(GO:0001054)
1.2	7.2	GO:0015245	fatty acid transporter activity(GO:0015245)
1.2	2.4	GO:0051371	muscle alpha-actinin binding(GO:0051371)
1.2	3.6	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
1.2	9.6	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
1.2	5.9	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
1.2	11.8	GO:0035198	miRNA binding(GO:0035198)
1.2	7.1	GO:0005047	signal recognition particle binding(GO:0005047)
1.2	25.7	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
1.2	2.3	GO:0051021	GDP-dissociation inhibitor binding(GO:0051021)
1.2	24.4	GO:0070064	proline-rich region binding(GO:0070064)
1.2	4.6	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
1.2	3.5	GO:0008184	glycogen phosphorylase activity(GO:0008184)
1.2	4.6	GO:0004967	glucagon receptor activity(GO:0004967)
1.1	6.9	GO:0048156	tau protein binding(GO:0048156)
1.1	22.9	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
1.1	11.4	GO:0000295	adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346)
1.1	19.4	GO:0043014	alpha-tubulin binding(GO:0043014)
1.1	10.2	GO:0042301	phosphate ion binding(GO:0042301)
1.1	4.5	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
1.1	15.6	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
1.1	26.8	GO:0042805	actinin binding(GO:0042805)
1.1	8.9	GO:0030368	interleukin-17 receptor activity(GO:0030368)
1.1	12.2	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
1.1	3.3	GO:0034711	inhibin binding(GO:0034711)
1.1	3.3	GO:1990190	peptide-glutamate-N-acetyltransferase activity(GO:1990190)
1.1	2.2	GO:0015137	citrate transmembrane transporter activity(GO:0015137)
1.1	4.4	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
1.1	14.2	GO:0005521	lamin binding(GO:0005521)
1.1	3.3	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
1.1	3.3	GO:0030274	LIM domain binding(GO:0030274)
1.1	24.8	GO:0004190	aspartic-type endopeptidase activity(GO:0004190)
1.1	6.4	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
1.1	4.2	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
1.1	26.4	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
1.1	15.8	GO:0070412	R-SMAD binding(GO:0070412)
1.0	3.1	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
1.0	18.9	GO:0005537	mannose binding(GO:0005537)
1.0	5.2	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
1.0	9.4	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
1.0	8.3	GO:0070008	serine-type exopeptidase activity(GO:0070008)
1.0	7.2	GO:0043024	ribosomal small subunit binding(GO:0043024)
1.0	3.1	GO:0000405	bubble DNA binding(GO:0000405)
1.0	16.4	GO:0004383	guanylate cyclase activity(GO:0004383)
1.0	7.1	GO:0008308	voltage-gated anion channel activity(GO:0008308)
1.0	4.0	GO:0016833	oxo-acid-lyase activity(GO:0016833)
1.0	2.0	GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
1.0	5.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
1.0	7.0	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832)
1.0	5.0	GO:0005138	interleukin-6 receptor binding(GO:0005138)
1.0	4.0	GO:0032052	bile acid binding(GO:0032052)
1.0	31.7	GO:0016651	oxidoreductase activity, acting on NAD(P)H(GO:0016651)
1.0	3.0	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
1.0	2.9	GO:0008453	alanine-glyoxylate transaminase activity(GO:0008453)
1.0	8.8	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
1.0	22.4	GO:0051879	Hsp90 protein binding(GO:0051879)
1.0	10.7	GO:0046527	glucosyltransferase activity(GO:0046527)
1.0	11.6	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
1.0	119.8	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
1.0	15.4	GO:0035174	histone serine kinase activity(GO:0035174)
1.0	3.9	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
1.0	100.1	GO:0051015	actin filament binding(GO:0051015)
1.0	2.9	GO:0008511	sodium:potassium:chloride symporter activity(GO:0008511)
1.0	7.7	GO:0045499	chemorepellent activity(GO:0045499)
1.0	2.9	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
1.0	18.1	GO:0005112	Notch binding(GO:0005112)
0.9	3.8	GO:0031686	A1 adenosine receptor binding(GO:0031686)
0.9	306.4	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.9	13.6	GO:0030955	potassium ion binding(GO:0030955)
0.9	4.5	GO:0008143	poly(A) binding(GO:0008143)
0.9	37.3	GO:0051018	protein kinase A binding(GO:0051018)
0.9	17.7	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.9	8.8	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.9	9.7	GO:0030215	semaphorin receptor binding(GO:0030215)
0.9	24.6	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.9	4.4	GO:0005522	profilin binding(GO:0005522)
0.9	3.5	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.9	4.3	GO:0034046	poly(G) binding(GO:0034046)
0.9	12.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.9	0.9	GO:0016303	1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.9	17.2	GO:0019825	oxygen binding(GO:0019825)
0.9	5.1	GO:0008428	ribonuclease inhibitor activity(GO:0008428)
0.9	11.1	GO:0019956	chemokine binding(GO:0019956)
0.8	8.4	GO:0019841	retinol binding(GO:0019841)
0.8	44.4	GO:0000987	core promoter proximal region sequence-specific DNA binding(GO:0000987)
0.8	94.2	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.8	4.2	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.8	252.4	GO:0050839	cell adhesion molecule binding(GO:0050839)
0.8	8.3	GO:0052745	inositol phosphate phosphatase activity(GO:0052745)
0.8	6.6	GO:0043422	protein kinase B binding(GO:0043422)
0.8	8.2	GO:0010181	FMN binding(GO:0010181)
0.8	33.4	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.8	3.2	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.8	11.3	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.8	8.0	GO:0016278	lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.8	6.4	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.8	8.0	GO:0005542	folic acid binding(GO:0005542)
0.8	7.1	GO:0070491	repressing transcription factor binding(GO:0070491)
0.8	3.9	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.8	11.5	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.8	26.8	GO:0003678	DNA helicase activity(GO:0003678)
0.8	2.3	GO:0030626	U12 snRNA binding(GO:0030626)
0.7	14.9	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.7	7.4	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.7	2.2	GO:0003844	1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.7	3.0	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.7	8.1	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.7	6.6	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.7	12.4	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.7	5.1	GO:0030621	U4 snRNA binding(GO:0030621)
0.7	2.2	GO:0070300	phosphatidic acid binding(GO:0070300)
0.7	7.2	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.7	2.9	GO:0003865	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.7	2.1	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.7	28.1	GO:0004896	cytokine receptor activity(GO:0004896)
0.7	6.7	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.7	2.7	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.7	10.7	GO:0001540	beta-amyloid binding(GO:0001540)
0.7	12.0	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
0.7	2.0	GO:0015292	uniporter activity(GO:0015292)
0.7	2.0	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.7	66.6	GO:0003714	transcription corepressor activity(GO:0003714)
0.7	17.0	GO:0042162	telomeric DNA binding(GO:0042162)
0.7	2.0	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.6	0.6	GO:0038181	bile acid receptor activity(GO:0038181)
0.6	1.9	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.6	3.9	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.6	1.9	GO:0045134	uridine-diphosphatase activity(GO:0045134)
0.6	1.9	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.6	9.3	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.6	2.4	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.6	9.7	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.6	4.2	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.6	3.0	GO:0035325	Toll-like receptor binding(GO:0035325)
0.6	4.8	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.6	1.8	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.6	1.8	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.6	17.5	GO:0050661	NADP binding(GO:0050661)
0.6	5.2	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.6	1.7	GO:0004574	oligo-1,6-glucosidase activity(GO:0004574)
0.6	4.5	GO:0016421	CoA carboxylase activity(GO:0016421)
0.6	17.9	GO:0019838	growth factor binding(GO:0019838)
0.6	3.9	GO:0019992	diacylglycerol binding(GO:0019992)
0.6	2.2	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
0.5	13.7	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.5	9.8	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.5	1.1	GO:0008318	protein prenyltransferase activity(GO:0008318)
0.5	2.7	GO:0004586	ornithine decarboxylase activity(GO:0004586)
0.5	20.6	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.5	1.6	GO:0004140	dephospho-CoA kinase activity(GO:0004140)
0.5	8.3	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.5	8.3	GO:0015248	sterol transporter activity(GO:0015248)
0.5	1.0	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
0.5	4.6	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.5	2.5	GO:0089720	caspase binding(GO:0089720)
0.5	41.3	GO:0005085	guanyl-nucleotide exchange factor activity(GO:0005085)
0.5	43.9	GO:0030165	PDZ domain binding(GO:0030165)
0.5	2.5	GO:0005148	prolactin receptor binding(GO:0005148)
0.5	2.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.5	5.3	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.5	14.5	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.5	1.0	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.5	18.2	GO:0016875	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.5	5.2	GO:0017154	semaphorin receptor activity(GO:0017154)
0.5	6.0	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.5	20.9	GO:0019843	rRNA binding(GO:0019843)
0.5	0.9	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.5	1.4	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.4	0.9	GO:0031685	adenosine receptor binding(GO:0031685)
0.4	0.4	GO:0016849	phosphorus-oxygen lyase activity(GO:0016849)
0.4	1.3	GO:0009975	cyclase activity(GO:0009975)
0.4	2.6	GO:0001537	N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.4	2.6	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453)
0.4	4.2	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.4	1.2	GO:0050733	RS domain binding(GO:0050733)
0.4	6.9	GO:0008252	nucleotidase activity(GO:0008252) 5'-nucleotidase activity(GO:0008253)
0.4	6.8	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.4	1.6	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.4	2.4	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.4	0.4	GO:0070717	poly-purine tract binding(GO:0070717)
0.4	4.2	GO:0008417	fucosyltransferase activity(GO:0008417)
0.4	0.8	GO:0003896	DNA primase activity(GO:0003896)
0.4	11.5	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.4	1.9	GO:0031748	D1 dopamine receptor binding(GO:0031748)
0.4	8.5	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.4	3.3	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.4	1.8	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.4	5.4	GO:0033613	activating transcription factor binding(GO:0033613)
0.4	1.4	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.4	0.7	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.3	1.0	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.3	3.4	GO:0051183	vitamin transporter activity(GO:0051183)
0.3	0.7	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.3	3.3	GO:0008171	O-methyltransferase activity(GO:0008171)
0.3	4.1	GO:0016854	racemase and epimerase activity(GO:0016854)
0.3	4.1	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.3	6.9	GO:0036442	hydrogen-exporting ATPase activity(GO:0036442)
0.3	55.7	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.3	0.9	GO:0000171	ribonuclease MRP activity(GO:0000171)
0.3	8.5	GO:0043621	protein self-association(GO:0043621)
0.3	7.9	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.3	1.2	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768)
0.3	0.6	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.3	7.9	GO:0004177	aminopeptidase activity(GO:0004177)
0.3	3.0	GO:0002162	dystroglycan binding(GO:0002162)
0.3	0.8	GO:0044736	acid-sensing ion channel activity(GO:0044736)
0.3	4.1	GO:0032947	protein complex scaffold(GO:0032947)
0.3	0.3	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.3	0.5	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.3	0.8	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.3	1.0	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.3	13.2	GO:0003725	double-stranded RNA binding(GO:0003725)
0.3	2.5	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.3	3.0	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.2	1.4	GO:0008170	N-methyltransferase activity(GO:0008170)
0.2	8.2	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
0.2	4.9	GO:0051059	NF-kappaB binding(GO:0051059)
0.2	0.7	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.2	3.7	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.2	3.5	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.2	0.8	GO:0008486	endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.2	0.6	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.2	1.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2	0.8	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2	0.4	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.2	87.5	GO:0003700	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.2	5.7	GO:0050660	flavin adenine dinucleotide binding(GO:0050660)
0.2	1.0	GO:0004180	carboxypeptidase activity(GO:0004180)
0.2	1.3	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2	2.1	GO:0004576	oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2	1.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.2	0.9	GO:0030620	U2 snRNA binding(GO:0030620)
0.2	18.5	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.2	0.9	GO:0031386	protein tag(GO:0031386)
0.2	0.6	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.2	6.1	GO:0016763	transferase activity, transferring pentosyl groups(GO:0016763)
0.1	1.2	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.1	2.6	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1	27.2	GO:0003735	structural constituent of ribosome(GO:0003735)
0.1	0.8	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.1	1.9	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.1	0.7	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.1	22.1	GO:0030246	carbohydrate binding(GO:0030246)
0.1	1.1	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.1	0.6	GO:0031849	olfactory receptor binding(GO:0031849)
0.1	1.4	GO:0005504	fatty acid binding(GO:0005504)
0.1	0.5	GO:0050072	m7G(5')pppN diphosphatase activity(GO:0050072)
0.1	0.5	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1	5.2	GO:0003823	antigen binding(GO:0003823)
0.1	1.1	GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters(GO:0016894)
0.1	4.8	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.1	3.1	GO:0008237	metallopeptidase activity(GO:0008237)
0.1	0.7	GO:0016929	SUMO-specific protease activity(GO:0016929)
0.1	0.1	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1	0.9	GO:0004622	lysophospholipase activity(GO:0004622)
0.1	0.5	GO:0004875	complement receptor activity(GO:0004875)
0.1	0.2	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.0	2.0	GO:0016820	hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820)
0.0	2.4	GO:0004519	endonuclease activity(GO:0004519)
0.0	0.4	GO:0015266	protein channel activity(GO:0015266)
0.0	0.9	GO:0070330	aromatase activity(GO:0070330)
0.0	3.0	GO:0016503	pheromone receptor activity(GO:0016503)
0.0	3.5	GO:0004721	phosphoprotein phosphatase activity(GO:0004721)
0.0	1.4	GO:0019003	GDP binding(GO:0019003)
0.0	0.2	GO:0005501	retinoid binding(GO:0005501)
0.0	0.2	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.3	GO:0008276	protein methyltransferase activity(GO:0008276)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.8	118.8	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
8.3	241.0	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
6.6	158.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
5.1	148.4	PID WNT SIGNALING PATHWAY	Wnt signaling network
4.4	66.7	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
4.4	52.9	ST STAT3 PATHWAY	STAT3 Pathway
4.3	121.6	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
4.3	163.8	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
4.1	12.2	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
3.9	207.7	PID BMP PATHWAY	BMP receptor signaling
3.9	34.7	PID IGF1 PATHWAY	IGF1 pathway
3.8	71.8	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
3.8	229.7	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
3.6	43.1	PID EPO PATHWAY	EPO signaling pathway
3.6	57.5	ST G ALPHA S PATHWAY	G alpha s Pathway
3.6	71.0	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
3.5	45.7	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
3.4	10.2	PID IFNG PATHWAY	IFN-gamma pathway
3.3	69.0	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
3.3	29.3	PID IL5 PATHWAY	IL5-mediated signaling events
3.2	64.0	PID NECTIN PATHWAY	Nectin adhesion pathway
3.1	56.2	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
3.1	27.5	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
3.0	142.1	PID CERAMIDE PATHWAY	Ceramide signaling pathway
2.9	126.5	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
2.8	11.4	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
2.8	99.1	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
2.8	36.6	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
2.8	14.1	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
2.8	96.4	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
2.7	60.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
2.7	32.5	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
2.6	91.5	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
2.5	89.3	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
2.4	47.4	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
2.3	2.3	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
2.3	86.3	PID ILK PATHWAY	Integrin-linked kinase signaling
2.3	65.3	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
2.3	72.9	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
2.3	59.2	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
2.2	20.0	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
2.2	30.5	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
2.2	21.7	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
2.0	46.8	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
2.0	54.1	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
2.0	29.9	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
2.0	92.5	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
1.9	34.9	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
1.9	313.0	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
1.9	9.4	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
1.8	56.9	PID TGFBR PATHWAY	TGF-beta receptor signaling
1.8	29.3	PID S1P S1P3 PATHWAY	S1P3 pathway
1.8	93.2	PID NOTCH PATHWAY	Notch signaling pathway
1.8	32.7	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
1.8	380.1	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
1.7	18.9	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
1.6	38.7	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
1.5	2.9	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
1.4	15.8	PID ALK1 PATHWAY	ALK1 signaling events
1.4	27.3	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
1.4	67.3	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
1.4	5.7	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
1.4	5.6	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
1.4	9.8	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
1.3	13.5	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
1.3	7.8	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
1.3	3.9	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
1.3	6.4	PID S1P S1P1 PATHWAY	S1P1 pathway
1.3	11.5	PID IL2 1PATHWAY	IL2-mediated signaling events
1.3	53.4	PID AR PATHWAY	Coregulation of Androgen receptor activity
1.3	6.4	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
1.2	37.3	PID FGF PATHWAY	FGF signaling pathway
1.2	4.9	PID GLYPICAN 1PATHWAY	Glypican 1 network
1.2	10.9	PID CD40 PATHWAY	CD40/CD40L signaling
1.2	7.2	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
1.2	16.7	PID FOXO PATHWAY	FoxO family signaling
1.2	64.2	PID TELOMERASE PATHWAY	Regulation of Telomerase
1.1	8.0	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
1.1	3.3	PID FAS PATHWAY	FAS (CD95) signaling pathway
1.1	23.3	PID PI3KCI PATHWAY	Class I PI3K signaling events
1.1	11.9	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
1.1	6.4	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
1.1	45.5	PID RHOA REG PATHWAY	Regulation of RhoA activity
1.0	5.2	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
1.0	14.1	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
1.0	4.8	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.9	34.7	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.9	25.1	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.9	24.0	PID LKB1 PATHWAY	LKB1 signaling events
0.9	73.3	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.9	22.9	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.9	51.6	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.9	17.4	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.8	6.4	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.8	16.6	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.8	12.6	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.8	8.7	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.8	6.3	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.7	9.6	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.7	3.6	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.7	7.3	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.7	10.8	PID ARF6 PATHWAY	Arf6 signaling events
0.7	19.2	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.7	9.8	PID ARF 3PATHWAY	Arf1 pathway
0.7	17.3	PID P53 REGULATION PATHWAY	p53 pathway
0.7	16.6	PID IL12 2PATHWAY	IL12-mediated signaling events
0.7	6.8	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.7	7.8	PID SHP2 PATHWAY	SHP2 signaling
0.6	12.1	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.6	14.2	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.6	84.3	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.6	9.6	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.6	4.4	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.6	3.9	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.5	2.6	PID IL3 PATHWAY	IL3-mediated signaling events
0.4	7.2	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.4	7.9	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.4	8.4	PID MTOR 4PATHWAY	mTOR signaling pathway
0.4	1.4	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.3	12.8	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.3	6.5	PID TNF PATHWAY	TNF receptor signaling pathway
0.3	2.0	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.3	11.0	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.3	2.5	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.3	5.0	PID RAS PATHWAY	Regulation of Ras family activation
0.3	7.0	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.3	3.7	PID RAC1 PATHWAY	RAC1 signaling pathway
0.3	3.0	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.3	4.6	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.2	3.5	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.2	3.8	PID IL4 2PATHWAY	IL4-mediated signaling events
0.1	0.7	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.1	1.3	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.8	129.4	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
5.9	58.6	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
5.6	100.0	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
5.5	65.9	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
5.2	73.3	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
5.1	71.0	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
4.8	67.8	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
4.7	4.7	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
4.7	405.9	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
4.7	88.6	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
4.6	50.6	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
4.6	50.5	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
4.3	82.4	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
4.1	202.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
3.8	107.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
3.8	3.8	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
3.6	25.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
3.4	99.6	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
3.4	40.4	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
3.3	36.7	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
3.3	62.9	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
3.3	86.0	REACTOME FGFR LIGAND BINDING AND ACTIVATION	Genes involved in FGFR ligand binding and activation
3.2	83.6	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
3.2	47.3	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
3.0	57.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
2.9	61.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
2.9	37.4	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
2.8	8.5	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
2.7	21.9	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
2.7	49.3	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
2.6	23.8	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
2.6	102.8	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
2.6	13.0	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
2.6	10.4	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
2.5	45.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
2.4	28.9	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
2.4	12.0	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
2.4	24.0	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
2.4	21.4	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
2.4	44.8	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
2.3	23.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
2.3	25.3	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
2.3	11.4	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
2.3	18.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
2.2	44.5	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
2.2	13.3	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
2.2	30.9	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
2.2	185.4	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
2.2	19.4	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
2.1	23.4	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
2.1	17.0	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
2.1	10.6	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
2.1	35.5	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
2.1	33.3	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
2.1	144.7	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
2.0	54.6	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
2.0	42.1	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
2.0	2.0	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
2.0	41.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
1.9	3.9	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
1.9	28.9	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
1.9	49.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
1.8	58.6	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
1.8	31.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
1.8	38.1	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
1.8	90.1	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
1.8	31.9	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
1.8	42.4	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
1.7	55.5	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
1.7	27.7	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
1.7	106.8	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
1.7	17.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
1.7	6.7	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
1.7	102.2	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
1.7	26.6	REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE	Genes involved in MyD88:Mal cascade initiated on plasma membrane
1.7	16.5	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
1.6	19.8	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
1.6	29.1	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
1.6	162.1	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
1.6	57.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
1.5	12.4	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
1.5	10.8	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
1.5	6.1	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
1.5	30.3	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
1.5	25.3	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
1.5	47.5	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
1.5	4.4	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
1.5	25.1	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
1.5	42.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
1.4	4.3	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
1.4	18.6	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
1.4	21.4	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
1.4	81.7	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
1.4	55.6	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
1.4	10.8	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
1.3	5.1	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
1.3	24.1	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
1.3	29.0	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
1.3	3.8	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
1.3	11.3	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
1.2	13.6	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
1.2	18.0	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
1.2	13.1	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
1.2	21.4	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
1.2	19.7	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
1.2	13.9	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
1.2	10.4	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
1.1	5.7	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
1.1	3.4	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
1.1	5.4	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
1.1	20.4	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
1.1	23.6	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
1.1	8.5	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
1.1	24.2	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
1.0	13.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
1.0	7.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
1.0	48.2	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
1.0	100.4	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
1.0	2.0	REACTOME SIGNALING BY FGFR MUTANTS	Genes involved in Signaling by FGFR mutants
1.0	11.9	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
1.0	21.7	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
1.0	7.7	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
1.0	14.4	REACTOME PURINE METABOLISM	Genes involved in Purine metabolism
1.0	20.1	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
1.0	13.3	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.9	21.7	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.9	3.7	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.9	1.9	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.9	44.3	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.9	4.6	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.9	4.4	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.9	5.1	REACTOME LIPOPROTEIN METABOLISM	Genes involved in Lipoprotein metabolism
0.8	7.6	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.8	8.4	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.8	35.0	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.8	3.3	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.8	9.9	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.8	4.8	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.8	14.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.8	5.3	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.7	13.4	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.7	7.4	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.7	8.0	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.7	12.9	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.7	12.1	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.7	4.9	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.7	6.3	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.7	7.9	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.7	65.0	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.6	6.5	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.6	3.2	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.6	6.2	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.6	12.9	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.5	13.1	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.5	35.0	REACTOME GLUCOSE METABOLISM	Genes involved in Glucose metabolism
0.5	4.3	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.5	4.8	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.5	7.7	REACTOME G1 PHASE	Genes involved in G1 Phase
0.5	2.5	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.5	17.1	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.5	3.0	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.5	5.9	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.4	1.8	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.4	10.6	REACTOME SPHINGOLIPID METABOLISM	Genes involved in Sphingolipid metabolism
0.4	6.9	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.4	3.8	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.4	3.9	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.4	10.5	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.4	3.6	REACTOME PI3K CASCADE	Genes involved in PI3K Cascade
0.4	1.1	REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.3	2.1	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.3	1.0	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
0.3	8.7	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.3	8.7	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.3	1.3	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.3	3.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.3	10.0	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.3	3.6	REACTOME SIGNALING BY FGFR	Genes involved in Signaling by FGFR
0.3	7.1	REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION	Genes involved in 3' -UTR-mediated translational regulation
0.3	5.9	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2	2.5	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.2	6.9	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.2	0.5	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.2	2.1	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.2	2.1	REACTOME ASPARAGINE N LINKED GLYCOSYLATION	Genes involved in Asparagine N-linked glycosylation
0.2	4.3	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.1	13.1	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.1	0.7	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.1	9.4	REACTOME DIABETES PATHWAYS	Genes involved in Diabetes pathways
0.1	0.5	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.1	1.8	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1	1.8	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1	0.8	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	2.5	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.1	2.8	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	2.0	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	1.0	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1	0.5	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.0	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.4	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport

Results for Mecp2

Z-value: 2.56

Motif logo

Transcription factors associated with Mecp2

Activity-expression correlation:

Activity profile of Mecp2 motif

Sorted Z-values of Mecp2 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Mecp2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: