Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation
Downloads

Results for Mbd2

Z-value: 0.47

Motif logo

logo of

Transcription factors associated with Mbd2

Gene Symbol Gene ID Gene Info
Mbd2
ENSRNOG00000011853 methyl-CpG binding domain protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mbd2rn6_v1_chr18_+_65814026_658140260.331.2e-09Click!

Activity profile of Mbd2 motif

Sorted Z-values of Mbd2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_172459165 15.50 ENSRNOT00000057473
Schip1
schwannomin interacting protein 1
chr5_+_148193710 14.31 ENSRNOT00000088568
Adgrb2
adhesion G protein-coupled receptor B2
chr9_-_19372673 6.96 ENSRNOT00000073667
ENSRNOT00000079517
Clic5
chloride intracellular channel 5
chr14_-_82048251 6.34 ENSRNOT00000074734
Nat8l
N-acetyltransferase 8-like
chr6_-_102196138 6.04 ENSRNOT00000014132
Tmem229b
transmembrane protein 229B
chr15_+_83707735 5.97 ENSRNOT00000057843
Klf5
Kruppel-like factor 5
chr9_+_99998275 5.90 ENSRNOT00000074395
Gpc1
glypican 1
chrX_-_15428518 5.84 ENSRNOT00000075774
LOC108348172
proSAAS
chr3_+_7109920 5.74 ENSRNOT00000084092
ENSRNOT00000013809
Ralgds
ral guanine nucleotide dissociation stimulator
chr7_-_139483997 5.58 ENSRNOT00000086062
Col2a1
collagen type II alpha 1 chain
chr10_+_62674561 5.51 ENSRNOT00000019946
ENSRNOT00000056110
Ankrd13b
ankyrin repeat domain 13B
chrX_-_15327684 5.49 ENSRNOT00000009794
Pcsk1n
proprotein convertase subtilisin/kexin type 1 inhibitor
chr18_-_77322690 5.44 ENSRNOT00000058382
Nfatc1
nuclear factor of activated T-cells 1
chr5_-_144779212 5.07 ENSRNOT00000016230
Ncdn
neurochondrin
chr9_+_82571269 5.01 ENSRNOT00000026941
Speg
SPEG complex locus
chr12_+_23473270 4.81 ENSRNOT00000001935
Sh2b2
SH2B adaptor protein 2
chr3_-_176465162 4.62 ENSRNOT00000048807
Nkain4
Sodium/potassium transporting ATPase interacting 4
chr6_-_131926272 4.54 ENSRNOT00000084057
ENSRNOT00000088421
Bcl11b
B-cell CLL/lymphoma 11B
chr10_+_91254058 4.37 ENSRNOT00000087218
ENSRNOT00000065373
Fmnl1
formin-like 1
chr14_-_78902063 4.18 ENSRNOT00000088469
Ppp2r2c
protein phosphatase 2, regulatory subunit B, gamma
chr7_-_141093924 4.11 ENSRNOT00000086276
Nckap5l
NCK-associated protein 5-like
chr8_-_116965396 3.98 ENSRNOT00000042528
Bsn
bassoon (presynaptic cytomatrix protein)
chr5_+_166533181 3.89 ENSRNOT00000045063
Clstn1
calsyntenin 1
chr10_-_63952726 3.89 ENSRNOT00000090461
Doc2b
double C2 domain beta
chr11_+_86512797 3.81 ENSRNOT00000051680
Gp1bb
glycoprotein Ib platelet beta subunit
chr1_+_163663407 3.73 ENSRNOT00000088873
Thap12
THAP domain containing 12
chr14_+_75852060 3.67 ENSRNOT00000075975
Hs3st1
heparan sulfate-glucosamine 3-sulfotransferase 1
chr17_-_80320681 3.64 ENSRNOT00000023637
C1ql3
complement C1q like 3
chr10_-_89699836 3.42 ENSRNOT00000084311
Etv4
ets variant 4
chr5_-_64850427 3.41 ENSRNOT00000008883
Tmem246
transmembrane protein 246
chr10_+_82800704 3.35 ENSRNOT00000089497
Ppp1r9b
protein phosphatase 1, regulatory subunit 9B
chr11_+_86421106 3.30 ENSRNOT00000002599
LOC100362453
serine/threonine-protein phosphatase 2A catalytic subunit alpha-like
chr10_-_90393317 3.29 ENSRNOT00000028563
Fam171a2
family with sequence similarity 171, member A2
chr1_-_267245636 3.25 ENSRNOT00000082799
Sh3pxd2a
SH3 and PX domains 2A
chr1_-_265798167 3.20 ENSRNOT00000079483
Ldb1
LIM domain binding 1
chr10_+_4957326 3.16 ENSRNOT00000003458
Socs1
suppressor of cytokine signaling 1
chr12_+_47103314 2.93 ENSRNOT00000064910
Rnf10
ring finger protein 10
chr11_+_87722350 2.91 ENSRNOT00000000313
Scarf2
scavenger receptor class F, member 2
chr6_+_137997335 2.82 ENSRNOT00000006872
Tmem121
transmembrane protein 121
chr7_-_132757558 2.57 ENSRNOT00000021153
Slc2a13
solute carrier family 2 member 13
chrX_+_120859968 2.55 ENSRNOT00000085185
Wdr44
WD repeat domain 44
chr4_-_163119391 2.54 ENSRNOT00000086605
Chtopl1
chromatin target of PRMT1-like 1
chrX_+_15679254 2.48 ENSRNOT00000045256
Plp2
proteolipid protein 2
chr6_-_109162267 2.47 ENSRNOT00000077518
Nek9
NIMA-related kinase 9
chr7_+_130498199 2.47 ENSRNOT00000092684
ENSRNOT00000092431
Shank3
SH3 and multiple ankyrin repeat domains 3
chr7_+_53275676 2.40 ENSRNOT00000031986
E2f7
E2F transcription factor 7
chr1_-_215836641 2.39 ENSRNOT00000080246
Igf2
insulin-like growth factor 2
chr14_-_59323947 2.35 ENSRNOT00000004006
Stim2
stromal interaction molecule 2
chr7_-_58286770 2.34 ENSRNOT00000005258
Rab21
RAB21, member RAS oncogene family
chrX_+_120860178 2.25 ENSRNOT00000088661
Wdr44
WD repeat domain 44
chr5_+_156876706 2.13 ENSRNOT00000021864
Camk2n1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr7_+_25919867 2.12 ENSRNOT00000009625
ENSRNOT00000090153
Ric8b
RIC8 guanine nucleotide exchange factor B
chr1_+_274766283 2.11 ENSRNOT00000071541
Adra2a
adrenoceptor alpha 2A
chr5_+_58393233 2.11 ENSRNOT00000000142
Dnajb5
DnaJ heat shock protein family (Hsp40) member B5
chr16_+_19051965 2.09 ENSRNOT00000016399
Slc35e1
solute carrier family 35, member E1
chr1_+_80087684 2.06 ENSRNOT00000041215
Eml2
echinoderm microtubule associated protein like 2
chr2_+_218951451 2.03 ENSRNOT00000019190
Extl2
exostosin-like glycosyltransferase 2
chr5_+_173183990 2.03 ENSRNOT00000068062
Tmem240
transmembrane protein 240
chr17_+_9679628 2.03 ENSRNOT00000019569
ENSRNOT00000019393
Dbn1
drebrin 1
chr3_+_4083864 2.02 ENSRNOT00000006186
Fam69b
family with sequence similarity 69, member B
chr10_+_75365822 1.98 ENSRNOT00000055705
Vezf1
vascular endothelial zinc finger 1
chr8_-_49025917 1.95 ENSRNOT00000078816
Phldb1
pleckstrin homology-like domain, family B, member 1
chr18_-_63394690 1.94 ENSRNOT00000090078
ENSRNOT00000029431
Cep76
centrosomal protein 76
chr8_-_68966108 1.93 ENSRNOT00000012155
Smad6
SMAD family member 6
chr10_+_56591292 1.92 ENSRNOT00000023379
Ctdnep1
CTD nuclear envelope phosphatase 1
chr9_+_98924134 1.85 ENSRNOT00000027597
Twist2
twist family bHLH transcription factor 2
chr7_+_141355994 1.83 ENSRNOT00000081195
Smarcd1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr19_+_18079094 1.83 ENSRNOT00000029415
Tox3
TOX high mobility group box family member 3
chr8_+_48805684 1.82 ENSRNOT00000064041
Bcl9l
B-cell CLL/lymphoma 9-like
chr14_-_37871051 1.81 ENSRNOT00000003087
Slain2
SLAIN motif family, member 2
chr7_-_12085226 1.77 ENSRNOT00000088669
ENSRNOT00000079925
Onecut3
one cut domain, family member 3
chr8_+_122197027 1.75 ENSRNOT00000013050
Ubp1
upstream binding protein 1 (LBP-1a)
chr1_+_221612584 1.74 ENSRNOT00000090100
Atg2a
autophagy related 2A
chr1_-_254671596 1.70 ENSRNOT00000025450
Htr7
5-hydroxytryptamine receptor 7
chr2_+_218951141 1.69 ENSRNOT00000091001
Extl2
exostosin-like glycosyltransferase 2
chr8_-_116391158 1.59 ENSRNOT00000078720
ENSRNOT00000022550
Gnai2
G protein subunit alpha i2
chr1_-_221486633 1.56 ENSRNOT00000028509
Sac3d1
SAC3 domain containing 1
chr1_+_239398043 1.56 ENSRNOT00000087386
Tmem2
transmembrane protein 2
chr7_+_120125633 1.56 ENSRNOT00000012480
Sh3bp1
SH3-domain binding protein 1
chr3_+_114747410 1.53 ENSRNOT00000043414
Spata5l1
spermatogenesis associated 5-like 1
chr5_+_58393603 1.52 ENSRNOT00000080082
Dnajb5
DnaJ heat shock protein family (Hsp40) member B5
chr6_-_46631983 1.48 ENSRNOT00000045963
Sox11
SRY box 11
chr3_+_146980923 1.46 ENSRNOT00000011654
Nsfl1c
NSFL1 cofactor
chr1_-_167347490 1.43 ENSRNOT00000076499
Rhog
ras homolog family member G
chr1_-_221015929 1.43 ENSRNOT00000028137
Sipa1
signal-induced proliferation-associated 1
chr5_+_134593517 1.43 ENSRNOT00000013471
Efcab14
EF-hand calcium binding domain 14
chr3_-_164095878 1.42 ENSRNOT00000079414
B4galt5
beta-1,4-galactosyltransferase 5
chr2_-_206274079 1.41 ENSRNOT00000056079
Hipk1
homeodomain interacting protein kinase 1
chr4_+_157453069 1.39 ENSRNOT00000088622
Mlf2
myeloid leukemia factor 2
chr3_-_1924827 1.36 ENSRNOT00000006162
Cacna1b
calcium voltage-gated channel subunit alpha1 B
chr15_+_108908607 1.35 ENSRNOT00000089455
Zic2
Zic family member 2
chr2_-_189899103 1.34 ENSRNOT00000010455
Chtop
chromatin target of PRMT1
chr3_+_111049118 1.29 ENSRNOT00000088870
Spint1
serine peptidase inhibitor, Kunitz type 1
chr7_+_139271698 1.14 ENSRNOT00000079388
Slc48a1
solute carrier family 48 member 1
chr9_-_44786041 1.14 ENSRNOT00000067197
Rev1
REV1, DNA directed polymerase
chr3_+_111049315 1.11 ENSRNOT00000017223
Spint1
serine peptidase inhibitor, Kunitz type 1
chr2_-_189899325 1.09 ENSRNOT00000017561
Chtop
chromatin target of PRMT1
chr19_-_56054142 1.08 ENSRNOT00000051945
Vps9d1
VPS9 domain containing 1
chr10_-_84698886 1.05 ENSRNOT00000067542
Nfe2l1
nuclear factor, erythroid 2-like 1
chr1_+_228395558 0.97 ENSRNOT00000065411
Osbp
oxysterol binding protein
chr3_-_83306781 0.92 ENSRNOT00000014088
Ttc17
tetratricopeptide repeat domain 17
chr6_+_2569013 0.92 ENSRNOT00000008988
Atl2
atlastin GTPase 2
chr5_+_150459713 0.92 ENSRNOT00000081681
ENSRNOT00000074251
Taf12
TATA-box binding protein associated factor 12
chrX_+_136466779 0.90 ENSRNOT00000093268
ENSRNOT00000068717
Arhgap36
Rho GTPase activating protein 36
chr10_-_90127600 0.89 ENSRNOT00000028368
Lsm12
LSM12 homolog
chr12_-_46718355 0.87 ENSRNOT00000030031
Rab35
RAB35, member RAS oncogene family
chr4_+_157452607 0.84 ENSRNOT00000022467
Mlf2
myeloid leukemia factor 2
chr4_-_115157263 0.83 ENSRNOT00000015296
Tet3
tet methylcytosine dioxygenase 3
chr1_-_254671778 0.81 ENSRNOT00000025493
Htr7
5-hydroxytryptamine receptor 7
chr7_-_63045728 0.74 ENSRNOT00000039532
Lemd3
LEM domain containing 3
chr3_+_108795235 0.70 ENSRNOT00000007028
Spred1
sprouty-related, EVH1 domain containing 1
chr7_-_134560713 0.68 ENSRNOT00000006621
Yaf2
YY1 associated factor 2
chr2_-_197935567 0.67 ENSRNOT00000085404
Rprd2
regulation of nuclear pre-mRNA domain containing 2
chr11_+_82466071 0.63 ENSRNOT00000036958
Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr19_+_52086325 0.62 ENSRNOT00000020341
Necab2
N-terminal EF-hand calcium binding protein 2
chr9_+_42620006 0.62 ENSRNOT00000019966
Hs6st1
heparan sulfate 6-O-sulfotransferase 1
chr8_+_115069095 0.61 ENSRNOT00000014770
Dusp7
dual specificity phosphatase 7
chr1_+_165724451 0.48 ENSRNOT00000025827
Fam168a
family with sequence similarity 168, member A
chr7_+_116671948 0.43 ENSRNOT00000077773
ENSRNOT00000029711
Gli4
GLI family zinc finger 4
chr5_+_136683592 0.43 ENSRNOT00000085527
Slc6a9
solute carrier family 6 member 9
chr10_+_110469290 0.41 ENSRNOT00000054919
Foxk2
forkhead box K2
chr15_-_25933268 0.41 ENSRNOT00000067735
Exoc5
exocyst complex component 5
chr6_-_108415093 0.39 ENSRNOT00000031650
Syndig1l
synapse differentiation inducing 1-like
chr5_+_60250546 0.38 ENSRNOT00000017707
Zcchc7
zinc finger CCHC-type containing 7
chr19_+_56179111 0.36 ENSRNOT00000046155
Tcf25
transcription factor 25
chr2_-_24923128 0.34 ENSRNOT00000044087
Pde8b
phosphodiesterase 8B
chr17_+_72240802 0.33 ENSRNOT00000025993
ENSRNOT00000090453
Atp5c1
ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
chr17_-_32953641 0.30 ENSRNOT00000023332
Wrnip1
Werner helicase interacting protein 1
chr10_-_82197848 0.28 ENSRNOT00000081307
Cacna1g
calcium voltage-gated channel subunit alpha1 G
chr17_-_10208360 0.27 ENSRNOT00000087397
Unc5a
unc-5 netrin receptor A
chr10_-_35800120 0.27 ENSRNOT00000004361
Maml1
mastermind-like transcriptional coactivator 1
chr1_-_164977633 0.26 ENSRNOT00000029629
Rnf169
ring finger protein 169
chr6_-_22281886 0.25 ENSRNOT00000039375
Spast
spastin
chr19_+_56054212 0.24 ENSRNOT00000022324
Zfp276
zinc finger protein (C2H2 type) 276
chr7_-_64341207 0.24 ENSRNOT00000006051
Tmem5
transmembrane protein 5
chr6_+_136041777 0.21 ENSRNOT00000014395
Mark3
microtubule affinity regulating kinase 3
chr13_+_90532326 0.19 ENSRNOT00000008944
Dcaf8
DDB1 and CUL4 associated factor 8
chr10_+_29289203 0.19 ENSRNOT00000067013
Pwwp2a
PWWP domain containing 2A
chr5_-_152198813 0.16 ENSRNOT00000082953
Hmgn2
high mobility group nucleosomal binding domain 2
chr18_+_86071662 0.12 ENSRNOT00000064901
Rttn
rotatin
chr1_-_222590112 0.11 ENSRNOT00000028763
ENSRNOT00000091990
Mark2
microtubule affinity regulating kinase 2
chr2_-_210088949 0.11 ENSRNOT00000070994
Rbm15
RNA binding motif protein 15
chr1_-_127599257 0.10 ENSRNOT00000018436
Asb7
ankyrin repeat and SOCS box-containing 7
chr8_+_117486083 0.09 ENSRNOT00000027552
ENSRNOT00000088705
Prkar2a
protein kinase cAMP-dependent type 2 regulatory subunit alpha
chr15_+_25933483 0.08 ENSRNOT00000018972
Ap5m1
adaptor-related protein complex 5, mu 1 subunit
chr5_-_166726794 0.08 ENSRNOT00000022799
Slc25a33
solute carrier family 25 member 33
chr7_-_130408187 0.07 ENSRNOT00000015374
Chkb
choline kinase beta
chrX_+_69580015 0.07 ENSRNOT00000057920
Fam155b
family with sequence similarity 155, member B
chr18_-_28495937 0.05 ENSRNOT00000027194
Dnajc18
DnaJ heat shock protein family (Hsp40) member C18
chr6_+_136279496 0.04 ENSRNOT00000091946
Apopt1
apoptogenic 1, mitochondrial
chr2_+_198231291 0.04 ENSRNOT00000078288
ENSRNOT00000046739
Otud7b
OTU deubiquitinase 7B
chr15_-_4022223 0.01 ENSRNOT00000081997
Zswim8
zinc finger, SWIM-type containing 8

Network of associatons between targets according to the STRING database.

First level regulatory network of Mbd2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 5.9 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
1.6 6.3 GO:0051944 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
1.4 5.4 GO:0002337 B-1a B cell differentiation(GO:0002337)
1.3 1.3 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
1.2 3.7 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
1.1 3.3 GO:2000474 regulation of opioid receptor signaling pathway(GO:2000474)
1.0 7.0 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.9 5.6 GO:0071306 cellular response to vitamin E(GO:0071306)
0.8 3.2 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.7 15.5 GO:0008210 estrogen metabolic process(GO:0008210)
0.7 4.8 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.7 2.0 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.7 4.0 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.6 2.5 GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.6 2.9 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.6 7.0 GO:0002024 diet induced thermogenesis(GO:0002024)
0.5 3.2 GO:0072675 osteoclast fusion(GO:0072675)
0.5 2.1 GO:0071883 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) thermoception(GO:0050955) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.5 6.0 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.5 3.4 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.5 1.9 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.5 2.4 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.5 1.4 GO:0042631 cellular response to water deprivation(GO:0042631)
0.4 3.3 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.4 3.2 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.3 2.4 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.3 2.1 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.3 4.4 GO:0051014 actin filament severing(GO:0051014)
0.3 1.4 GO:0061072 iris morphogenesis(GO:0061072)
0.3 3.9 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.2 4.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.2 2.4 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.2 2.3 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.2 1.8 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.2 1.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.2 2.3 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.2 0.8 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.2 0.6 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2 18.2 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 1.9 GO:1904259 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 2.4 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 1.6 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 1.1 GO:0015886 heme transport(GO:0015886)
0.1 1.7 GO:0044804 nucleophagy(GO:0044804)
0.1 1.5 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 1.9 GO:0046599 regulation of centriole replication(GO:0046599)
0.1 0.4 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 0.3 GO:0003162 atrioventricular node development(GO:0003162)
0.1 1.9 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 2.6 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 1.4 GO:0001956 positive regulation of neurotransmitter secretion(GO:0001956)
0.1 4.1 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.3 GO:0035106 operant conditioning(GO:0035106)
0.1 0.7 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 1.8 GO:0031112 positive regulation of microtubule polymerization or depolymerization(GO:0031112)
0.1 0.9 GO:0036010 protein localization to endosome(GO:0036010)
0.1 5.1 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.1 5.0 GO:0055013 cardiac muscle cell development(GO:0055013)
0.1 2.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 1.4 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.1 1.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 5.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 0.3 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 4.5 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 2.5 GO:0050807 regulation of synapse organization(GO:0050807)
0.0 3.6 GO:0006986 response to unfolded protein(GO:0006986)
0.0 1.0 GO:0044144 regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.0 1.7 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0 2.0 GO:0001885 endothelial cell development(GO:0001885)
0.0 2.1 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 3.8 GO:0007596 blood coagulation(GO:0007596)
0.0 0.9 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 5.8 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.7 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.9 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 2.4 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.0 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:1990314 cellular response to insulin-like growth factor stimulus(GO:1990314)
0.0 2.1 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.2 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.0 0.1 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.3 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.5 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 3.0 GO:0007265 Ras protein signal transduction(GO:0007265)
0.0 2.9 GO:0006470 protein dephosphorylation(GO:0006470)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.8 2.3 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.6 3.3 GO:0044326 dendritic spine neck(GO:0044326)
0.5 1.5 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.5 5.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.3 2.0 GO:0044308 axonal spine(GO:0044308)
0.3 3.7 GO:0005796 Golgi lumen(GO:0005796)
0.2 6.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.2 5.9 GO:0035371 microtubule plus-end(GO:0035371)
0.2 4.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 1.8 GO:0071564 npBAF complex(GO:0071564)
0.2 0.9 GO:0000125 PCAF complex(GO:0000125)
0.1 2.1 GO:0045180 basal cortex(GO:0045180)
0.1 7.0 GO:0032420 stereocilium(GO:0032420)
0.1 2.4 GO:0000346 transcription export complex(GO:0000346)
0.1 0.8 GO:0001940 male pronucleus(GO:0001940)
0.1 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 3.9 GO:0031201 SNARE complex(GO:0031201)
0.1 3.2 GO:0002102 podosome(GO:0002102)
0.1 4.4 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 1.7 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 3.6 GO:0005581 collagen trimer(GO:0005581)
0.1 5.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.9 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287)
0.0 4.8 GO:0005884 actin filament(GO:0005884)
0.0 1.6 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.3 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 1.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 5.7 GO:0005903 brush border(GO:0005903)
0.0 0.7 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 13.5 GO:0005667 transcription factor complex(GO:0005667)
0.0 2.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.4 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.9 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 3.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.1 GO:0072686 mitotic spindle(GO:0072686)
0.0 6.9 GO:0097060 synaptic membrane(GO:0097060)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 1.9 GO:0005814 centriole(GO:0005814)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.2 GO:0016605 PML body(GO:0016605)
0.0 0.7 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 3.8 GO:0005874 microtubule(GO:0005874)
0.0 0.3 GO:0032809 neuronal cell body membrane(GO:0032809)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.4 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
1.2 3.7 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
1.2 5.9 GO:0070052 collagen V binding(GO:0070052)
1.1 5.7 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.9 5.6 GO:0042289 MHC class II protein binding(GO:0042289)
0.7 2.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.6 1.9 GO:0070698 type I activin receptor binding(GO:0070698)
0.6 3.7 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.6 4.8 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.6 4.0 GO:0045503 dynein light chain binding(GO:0045503)
0.6 3.3 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.5 2.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.4 3.2 GO:0030274 LIM domain binding(GO:0030274)
0.4 6.4 GO:0005522 profilin binding(GO:0005522)
0.4 2.5 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.3 3.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.3 5.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.2 0.8 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 1.8 GO:0034056 estrogen response element binding(GO:0034056)
0.2 2.5 GO:0051378 serotonin binding(GO:0051378)
0.2 2.6 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.1 2.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.1 GO:0015232 heme transporter activity(GO:0015232)
0.1 2.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 3.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.7 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 2.5 GO:0019956 chemokine binding(GO:0019956)
0.1 4.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 1.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 7.0 GO:0005254 chloride channel activity(GO:0005254)
0.1 7.3 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.1 0.6 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.1 13.7 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.1 1.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 3.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 2.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 2.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.3 GO:0005042 netrin receptor activity(GO:0005042)
0.1 3.2 GO:0019003 GDP binding(GO:0019003)
0.0 1.0 GO:0015248 sterol transporter activity(GO:0015248)
0.0 3.6 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 1.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 12.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.4 GO:0015187 sodium:amino acid symporter activity(GO:0005283) glycine transmembrane transporter activity(GO:0015187)
0.0 3.2 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 1.1 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.5 GO:0051117 ATPase binding(GO:0051117)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 2.9 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 1.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.9 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 5.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 5.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 7.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 1.9 PID BMP PATHWAY BMP receptor signaling
0.1 2.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 2.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 2.2 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.9 PID MYC PATHWAY C-MYC pathway
0.0 2.6 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 1.4 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 1.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 3.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.5 PID E2F PATHWAY E2F transcription factor network
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.4 PID INSULIN PATHWAY Insulin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.7 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.4 8.0 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.4 10.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.3 3.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 2.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 4.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 3.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 2.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 1.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 6.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.4 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 1.8 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.6 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 2.5 REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.0 0.9 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.1 REACTOME DNA REPAIR Genes involved in DNA Repair