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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Maff

Z-value: 0.60

Motif logo

Transcription factors associated with Maff

Gene Symbol Gene ID Gene Info
ENSRNOG00000012886 MAF bZIP transcription factor F

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Maffrn6_v1_chr7_+_120580743_120580743-0.285.0e-07Click!

Activity profile of Maff motif

Sorted Z-values of Maff motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_29171783 24.55 ENSRNOT00000079235
myosin binding protein C, slow type
chr15_+_2527343 17.73 ENSRNOT00000089013
dual specificity phosphatase 13
chr15_-_28104206 17.23 ENSRNOT00000032536
angiogenin, ribonuclease A family, member 2
chr15_+_2734068 16.79 ENSRNOT00000017663
dual specificity phosphatase 13
chr10_-_93675991 16.59 ENSRNOT00000090662
membrane associated ring-CH-type finger 10
chr3_-_72289310 16.46 ENSRNOT00000038250
reticulon 4 receptor-like 2
chr10_+_53818818 16.23 ENSRNOT00000057260
myosin heavy chain 8
chr9_-_95290931 15.64 ENSRNOT00000025300
DnaJ heat shock protein family (Hsp40) member B3
chr16_-_68832862 15.29 ENSRNOT00000016348
POTE ankyrin domain family, member G
chr15_+_28028521 15.06 ENSRNOT00000089631

chr18_-_28454756 14.29 ENSRNOT00000040091
spermatogenesis associated 24
chr8_-_73164620 13.64 ENSRNOT00000031988
talin 2
chr7_+_51794173 13.39 ENSRNOT00000043774
otogelin-like
chr7_-_124999137 13.11 ENSRNOT00000039228
patatin-like phospholipase domain containing 5
chr14_+_34389991 12.42 ENSRNOT00000002953
phosducin-like 2
chr5_-_19368431 10.33 ENSRNOT00000012819
cytochrome P450, family 7, subfamily a, polypeptide 1
chr16_-_20800646 10.17 ENSRNOT00000083281
cartilage oligomeric matrix protein
chr6_+_52702544 9.57 ENSRNOT00000014252
EF-hand calcium binding domain 10
chr18_+_74006046 9.40 ENSRNOT00000086400

chr14_-_72380330 9.04 ENSRNOT00000082653
ENSRNOT00000081878
ENSRNOT00000006727
cytoplasmic polyadenylation element binding protein 2
chr1_-_102013243 8.98 ENSRNOT00000042115
ATP binding cassette subfamily C member 6
chr6_-_26281300 8.64 ENSRNOT00000078750
similar to RIKEN cDNA 4930548H24
chr18_+_40883224 7.87 ENSRNOT00000039733
laeverin
chr2_-_192960294 7.79 ENSRNOT00000012420
late cornified envelope protein 5A-like
chr5_+_28850950 7.58 ENSRNOT00000009759
transmembrane protein 64
chr6_+_54488038 7.37 ENSRNOT00000084661
ENSRNOT00000005637
sorting nexin 13
chrX_+_13441558 7.26 ENSRNOT00000030170
similar to Ferritin light chain (Ferritin L subunit)
chr11_-_32469566 7.20 ENSRNOT00000002718
similar to RIKEN cDNA 4930563D23
chr10_-_13168217 7.14 ENSRNOT00000087768
elongin B
chr9_+_8349033 6.75 ENSRNOT00000073775
hypothetical protein LOC100360856
chr2_-_210943620 6.64 ENSRNOT00000026750
G protein-coupled receptor 61
chr13_-_111765944 6.39 ENSRNOT00000073041
synaptotagmin 14
chr7_-_117267402 5.92 ENSRNOT00000088945
plectin
chr20_+_6351458 5.67 ENSRNOT00000091731
cyclin-dependent kinase inhibitor 1A
chrX_-_123788898 5.60 ENSRNOT00000009123
A-kinase anchoring protein 14
chr9_+_47386626 5.47 ENSRNOT00000021270
solute carrier family 9 member A2
chr16_-_14382641 5.30 ENSRNOT00000018723
growth hormone inducible transmembrane protein
chr8_+_128829680 5.25 ENSRNOT00000025279
myelin-associated oligodendrocyte basic protein
chr6_-_86822094 4.97 ENSRNOT00000006531
FK506 binding protein 3
chr7_-_117267803 4.53 ENSRNOT00000082271
plectin
chr14_+_42402081 4.17 ENSRNOT00000092933
BEN domain containing 4
chr3_-_147188929 4.11 ENSRNOT00000055455
RAD21 cohesin complex component like 1
chr9_-_82154266 4.05 ENSRNOT00000024283
crystallin, beta A2
chr5_+_127571312 3.63 ENSRNOT00000090817
ENSRNOT00000077808
ENSRNOT00000072263
solute carrier family 1 member 7
chr5_+_127571114 3.48 ENSRNOT00000016557
solute carrier family 1 member 7
chr5_-_28737719 3.26 ENSRNOT00000009718
N-terminal EF-hand calcium binding protein 1
chr8_-_1450138 3.25 ENSRNOT00000008062
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr10_+_87819150 3.25 ENSRNOT00000073764
ENSRNOT00000064626
hypothetical protein LOC680442
chr8_-_109576353 3.08 ENSRNOT00000010320
protein phosphatase 2, regulatory subunit B'', alpha
chr1_-_87825333 3.01 ENSRNOT00000072689
zinc finger protein 74
chr4_-_114768029 2.99 ENSRNOT00000083404
T-cell leukemia homeobox 2
chr4_-_113902399 2.94 ENSRNOT00000087788
T-cell leukemia homeobox 2
chr2_-_193007929 2.78 ENSRNOT00000056486
late cornified envelope protein 1C-like
chr6_-_75470347 2.75 ENSRNOT00000047882
similar to 40S ribosomal protein S19
chr3_-_11410732 2.69 ENSRNOT00000034930
similar to Hypothetical UPF0184 protein C9orf16 homolog
chr2_+_208373154 2.66 ENSRNOT00000082943
ENSRNOT00000050538
adenosine receptor A3-like
chr2_-_14701903 2.66 ENSRNOT00000051895
cytochrome c oxidase subunit 7C
chr2_-_153140894 2.62 ENSRNOT00000075166

chr1_-_88240057 2.61 ENSRNOT00000073092
zinc finger protein 569
chr2_-_193042323 2.58 ENSRNOT00000012464

chr15_-_109394905 2.57 ENSRNOT00000019602
ENSRNOT00000078424
transmembrane and tetratricopeptide repeat containing 4
chr19_-_43848937 2.52 ENSRNOT00000044844
lactate dehydrogenase D
chr2_+_160291450 2.48 ENSRNOT00000075563

chrX_-_107762590 2.45 ENSRNOT00000072739
ESX homeobox 1
chr15_-_28786094 2.45 ENSRNOT00000044250
olfactory receptor 1639
chr8_-_3882077 2.22 ENSRNOT00000071085
vomeronasal 2 receptor, 25
chr10_+_34712870 2.22 ENSRNOT00000045600
olfactory receptor 1396
chrX_+_15321713 2.19 ENSRNOT00000071835
GTPase ERas
chr10_+_12602388 2.14 ENSRNOT00000060989
olfactory receptor 1373
chr8_+_408001 2.05 ENSRNOT00000046058
guanylate cyclase 1 soluble subunit alpha 2
chr15_+_33596301 1.96 ENSRNOT00000022563
interleukin 25
chr17_-_38858331 1.91 ENSRNOT00000059738
Prolactin family 2, subfamily c, member 1
chr1_+_228337767 1.88 ENSRNOT00000066247
PAT1 homolog 1, processing body mRNA decay factor
chr15_-_28806752 1.85 ENSRNOT00000047436
olfactory receptor 1640
chr13_-_79899479 1.85 ENSRNOT00000035815
similar to hypothetical protein
chr20_-_11634137 1.64 ENSRNOT00000083064
keratin associated protein 12-1-like
chr12_-_50404550 1.33 ENSRNOT00000073072
crystallin, beta B1
chr10_-_74001895 1.27 ENSRNOT00000005658
vacuole membrane protein 1
chr14_-_21127868 1.23 ENSRNOT00000020608
ENSRNOT00000092172
RUN and FYVE domain containing 3
chr11_+_71151132 1.06 ENSRNOT00000082594
ENSRNOT00000082435
RUN and cysteine rich domain containing beclin 1 interacting protein
chr1_+_31700953 1.05 ENSRNOT00000020251
exocyst complex component 3
chr10_+_87808493 0.98 ENSRNOT00000065405
hypothetical protein LOC680428
chr4_+_147832136 0.96 ENSRNOT00000064603
rhodopsin
chr4_-_117568348 0.95 ENSRNOT00000071447
N-acetyltransferase 8 (GCN5-related) family member 2
chr2_-_193101051 0.93 ENSRNOT00000065242

chr1_-_170073473 0.88 ENSRNOT00000085141
olfactory receptor 196
chrX_-_45806198 0.84 ENSRNOT00000066663
proline rich and Gla domain 1
chr1_-_221448570 0.84 ENSRNOT00000075165
zinc finger protein-like 1
chr5_+_48224994 0.71 ENSRNOT00000068028
Ras-related GTP binding D
chrX_-_10772633 0.70 ENSRNOT00000035153
ubiquitin-conjugating enzyme E2Q family member 2-like
chr1_-_88826302 0.61 ENSRNOT00000028275
leucine rich repeat and fibronectin type III domain containing 3
chr6_-_49089855 0.59 ENSRNOT00000006526
thyroid peroxidase
chr13_-_27158628 0.57 ENSRNOT00000003475
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A
chr13_-_36101411 0.57 ENSRNOT00000074471
transmembrane protein 37
chr6_-_78817641 0.54 ENSRNOT00000072117

chr19_-_49510901 0.54 ENSRNOT00000082929
ENSRNOT00000079969
hypothetical protein LOC687399
chr1_-_89483988 0.53 ENSRNOT00000028603
FXYD domain-containing ion transport regulator 7
chr16_+_19881122 0.53 ENSRNOT00000060404
DET1 and DDB1 associated 1
chr1_+_87009730 0.49 ENSRNOT00000027537
enoyl-CoA hydratase 1
chr10_-_43931094 0.49 ENSRNOT00000039778
olfactory receptor 1415
chr1_-_99985422 0.30 ENSRNOT00000025701
kallikrein 1-related peptidase C2
chr10_+_60043848 0.27 ENSRNOT00000080593

chr7_-_3499697 0.17 ENSRNOT00000064311
olfactory receptor 878
chr7_+_16394354 0.13 ENSRNOT00000041157
olfactory receptor 1058
chr10_+_87832743 0.04 ENSRNOT00000055286
keratin associated protein 31-1
chr7_+_91384187 0.01 ENSRNOT00000005828
UTP23, small subunit processome component

Network of associatons between targets according to the STRING database.

First level regulatory network of Maff

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 24.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
2.3 9.0 GO:0045900 negative regulation of translational elongation(GO:0045900)
1.9 7.6 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
1.6 12.4 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
1.5 16.2 GO:0030049 muscle filament sliding(GO:0030049)
1.2 13.6 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
1.2 13.4 GO:0019321 pentose metabolic process(GO:0019321)
1.0 3.1 GO:0090249 cell motility involved in somitogenic axis elongation(GO:0090247) regulation of cell motility involved in somitogenic axis elongation(GO:0090249)
0.8 5.7 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.8 10.3 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857)
0.7 16.5 GO:0022038 corpus callosum development(GO:0022038)
0.7 3.3 GO:0006553 lysine metabolic process(GO:0006553)
0.6 7.3 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.5 10.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.5 10.2 GO:0003417 growth plate cartilage development(GO:0003417)
0.4 5.5 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.4 7.1 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.4 4.1 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.4 1.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.3 5.9 GO:0048484 enteric nervous system development(GO:0048484)
0.3 13.1 GO:0019433 triglyceride catabolic process(GO:0019433)
0.3 2.0 GO:0030222 eosinophil differentiation(GO:0030222)
0.3 34.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.2 10.6 GO:0018149 peptide cross-linking(GO:0018149)
0.2 7.9 GO:0043171 peptide catabolic process(GO:0043171)
0.2 2.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 2.7 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.2 1.9 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 2.1 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.1 1.0 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.1 0.7 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.1 17.2 GO:0090501 RNA phosphodiester bond hydrolysis(GO:0090501)
0.1 6.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 5.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 2.5 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.1 1.1 GO:0051601 exocyst localization(GO:0051601)
0.1 0.6 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 4.1 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 1.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.6 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 15.3 GO:0007283 spermatogenesis(GO:0007283)
0.0 18.6 GO:0016567 protein ubiquitination(GO:0016567)
0.0 1.3 GO:0007029 endoplasmic reticulum organization(GO:0007029)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 40.8 GO:0032982 myosin filament(GO:0032982)
1.9 5.7 GO:0070557 PCNA-p21 complex(GO:0070557)
1.0 7.1 GO:0070449 elongin complex(GO:0070449)
0.7 13.6 GO:0005916 fascia adherens(GO:0005916)
0.6 4.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.5 10.4 GO:0030056 hemidesmosome(GO:0030056)
0.4 9.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.4 10.6 GO:0001533 cornified envelope(GO:0001533)
0.4 16.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.3 5.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 2.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 11.1 GO:0005811 lipid particle(GO:0005811)
0.1 8.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 15.6 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 3.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 2.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 5.9 GO:0045095 keratin filament(GO:0045095)
0.1 1.2 GO:0071437 invadopodium(GO:0071437)
0.0 1.3 GO:0000421 pre-autophagosomal structure(GO:0000407) autophagosome membrane(GO:0000421)
0.0 1.1 GO:0000145 exocyst(GO:0000145)
0.0 1.0 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 8.4 GO:0005769 early endosome(GO:0005769)
0.0 6.6 GO:0043235 receptor complex(GO:0043235)
0.0 5.5 GO:0016324 apical plasma membrane(GO:0016324)
0.0 6.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 2.1 GO:0043209 myelin sheath(GO:0043209)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.7 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
1.9 24.5 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
1.7 10.2 GO:0005499 vitamin D binding(GO:0005499)
1.6 12.4 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.7 16.2 GO:0000146 microfilament motor activity(GO:0000146)
0.7 9.0 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.7 13.1 GO:0004806 triglyceride lipase activity(GO:0004806)
0.6 34.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.5 5.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.4 7.1 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.4 5.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.4 5.0 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.4 10.3 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.4 7.3 GO:0008199 ferric iron binding(GO:0008199)
0.3 7.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.3 10.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 1.9 GO:0034046 poly(G) binding(GO:0034046)
0.2 7.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.2 16.5 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.2 17.2 GO:0004540 ribonuclease activity(GO:0004540)
0.1 3.3 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1 13.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 13.4 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.1 1.0 GO:0009881 photoreceptor activity(GO:0009881)
0.1 5.4 GO:0051018 protein kinase A binding(GO:0051018)
0.1 6.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 2.7 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 16.6 GO:0016874 ligase activity(GO:0016874)
0.1 2.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 1.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 9.0 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 7.1 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 15.1 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 1.2 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.0 0.6 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.9 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.7 GO:0019003 GDP binding(GO:0019003)
0.0 1.7 GO:0005179 hormone activity(GO:0005179)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.4 5.9 PID ALK2 PATHWAY ALK2 signaling events
0.4 7.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 14.6 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 5.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 6.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.1 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 40.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.7 10.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.4 10.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.4 5.7 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.3 7.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.3 3.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 9.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 1.9 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.0 REACTOME OPSINS Genes involved in Opsins
0.1 2.1 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 2.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.1 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 2.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones