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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Mafb

Z-value: 1.01

Motif logo

Transcription factors associated with Mafb

Gene Symbol Gene ID Gene Info
ENSRNOG00000016037 MAF bZIP transcription factor B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mafbrn6_v1_chr3_-_156340913_1563409130.018.3e-01Click!

Activity profile of Mafb motif

Sorted Z-values of Mafb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_38828444 36.02 ENSRNOT00000001809
4-hydroxyphenylpyruvate dioxygenase
chr17_+_21382455 32.37 ENSRNOT00000019756
ELOVL fatty acid elongase 2
chr11_-_81444375 30.63 ENSRNOT00000058479
ENSRNOT00000078131
ENSRNOT00000080949
ENSRNOT00000080562
ENSRNOT00000084867
kininogen 1
chr13_+_89597138 30.34 ENSRNOT00000004662
apolipoprotein A2
chr7_+_28066635 28.92 ENSRNOT00000005844
phenylalanine hydroxylase
chr14_-_19072677 25.35 ENSRNOT00000060548
similar to alpha-fetoprotein
chr1_-_240601744 23.57 ENSRNOT00000024093
aldehyde dehydrogenase family 1, subfamily A7
chr1_-_224698514 23.55 ENSRNOT00000024234
solute carrier family 22, member 25
chr14_+_22553650 22.21 ENSRNOT00000092201
ENSRNOT00000002712
UDP glucuronosyltransferase 2 family, polypeptide B35
chr1_+_238222521 21.65 ENSRNOT00000024000
aldehyde dehydrogenase 1 family, member A1
chr7_+_116739062 21.09 ENSRNOT00000075837
ENSRNOT00000076670
ENSRNOT00000010065
rhophilin, Rho GTPase binding protein 1
chr1_-_162713610 19.76 ENSRNOT00000018091
aquaporin 11
chr16_+_6078122 19.33 ENSRNOT00000021407
choline dehydrogenase
chr4_+_154215250 17.90 ENSRNOT00000072465
murinoglobulin 2
chr10_-_38774449 17.63 ENSRNOT00000049820
liver-expressed antimicrobial peptide 2
chr7_+_11490852 16.98 ENSRNOT00000044484
cAMP responsive element binding protein 3-like 3
chr15_-_28104206 16.71 ENSRNOT00000032536
angiogenin, ribonuclease A family, member 2
chr8_+_48718329 16.68 ENSRNOT00000089763
solute carrier family 37 member 4
chr15_+_4077091 16.35 ENSRNOT00000011554
myozenin 1
chr15_+_4077951 16.25 ENSRNOT00000085266
myozenin 1
chr5_-_9429859 16.12 ENSRNOT00000009462
alcohol dehydrogenase, iron containing, 1
chr18_-_15089988 15.97 ENSRNOT00000074116
meprin A subunit beta
chr13_-_36101411 15.91 ENSRNOT00000074471
transmembrane protein 37
chr11_+_36743901 15.54 ENSRNOT00000085014
immunoglobulin superfamily, member 5
chr10_+_53781239 15.50 ENSRNOT00000082871
myosin heavy chain 2
chr10_+_56662242 15.29 ENSRNOT00000086919
asialoglycoprotein receptor 1
chr5_-_19368431 15.29 ENSRNOT00000012819
cytochrome P450, family 7, subfamily a, polypeptide 1
chr4_-_117568348 15.26 ENSRNOT00000071447
N-acetyltransferase 8 (GCN5-related) family member 2
chr1_+_106896790 15.04 ENSRNOT00000042952
ENSRNOT00000064193
anoctamin 5
chr9_+_49479023 14.93 ENSRNOT00000050922
ENSRNOT00000077111
POU class 3 homeobox 3
chr10_+_56662561 14.75 ENSRNOT00000025254
asialoglycoprotein receptor 1
chr10_-_7200499 14.74 ENSRNOT00000003633
4-aminobutyrate aminotransferase
chr19_-_25134055 14.55 ENSRNOT00000007519
MISP family member 3
chr16_-_49003246 14.46 ENSRNOT00000089501
acyl-CoA synthetase long-chain family member 1
chr11_+_61609370 14.10 ENSRNOT00000088880
ENSRNOT00000082533
GRAM domain containing 1C
chr7_+_101069104 14.06 ENSRNOT00000056894

chr13_-_56877611 13.96 ENSRNOT00000079040
ENSRNOT00000017195
complement factor H-related 1
chr4_-_30338679 13.90 ENSRNOT00000012050
paraoxonase 3
chr1_-_219312240 13.90 ENSRNOT00000066691
similar to hypothetical protein MGC37914
chr5_+_160306727 13.73 ENSRNOT00000016648
agmatinase
chr11_-_87921679 13.66 ENSRNOT00000084973
serpin family D member 1
chr12_-_19167015 13.43 ENSRNOT00000001797
gap junction protein, gamma 3
chr15_-_3650819 13.15 ENSRNOT00000014273
plasminogen activator, urokinase
chr2_+_127845034 13.06 ENSRNOT00000044804
La ribonucleoprotein domain family, member 1B
chr6_+_8284878 12.99 ENSRNOT00000009581
solute carrier family 3 member 1
chr6_-_129010271 12.31 ENSRNOT00000075378
serpin family A member 10
chr18_-_55859333 12.15 ENSRNOT00000025989
myozenin 3
chr11_-_87924816 11.93 ENSRNOT00000031819
serpin family D member 1
chr7_-_71226150 11.91 ENSRNOT00000005875
similar to Retinol dehydrogenase type II (RODH II) (29 k-protein)
chr9_-_73948583 11.82 ENSRNOT00000018097
myosin, light chain 1
chr1_-_99303048 11.34 ENSRNOT00000025631
similar to Kallikrein-1 precursor (Tissue kallikrein) (Kidney/pancreas/salivary gland kallikrein)
chr1_-_221919210 11.28 ENSRNOT00000092580
ENSRNOT00000028665
solute carrier family 22 member 12
chr14_+_2050483 11.26 ENSRNOT00000000047
solute carrier family 26 member 1
chr1_-_99870024 11.21 ENSRNOT00000085556

chr11_+_44089797 11.16 ENSRNOT00000060861
ferritin heavy chain-like
chr13_+_75177965 11.07 ENSRNOT00000007321
SEC16 homolog B, endoplasmic reticulum export factor
chr2_+_243502073 11.06 ENSRNOT00000015870
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr1_+_32199810 10.99 ENSRNOT00000036714
solute carrier family 6 member 19
chr2_+_78103387 10.93 ENSRNOT00000063951
protein FAM134B
chr1_+_264507985 10.91 ENSRNOT00000085811
paired box 2
chr13_-_56693968 10.82 ENSRNOT00000060160

chr10_+_53818818 10.71 ENSRNOT00000057260
myosin heavy chain 8
chr1_+_221236773 10.43 ENSRNOT00000051979
solute carrier family 25, member 45
chr5_+_152559577 10.40 ENSRNOT00000082245
solute carrier family 30 member 2
chr6_+_107517668 10.23 ENSRNOT00000013753
acyl-CoA thioesterase 4
chr5_+_137189473 10.13 ENSRNOT00000056815
hydroxypyruvate isomerase
chrX_-_110230610 10.08 ENSRNOT00000093401
serpin family A member 7
chr8_-_119012671 9.87 ENSRNOT00000028435
parathyroid hormone 1 receptor
chr6_+_127766470 9.75 ENSRNOT00000013138
serpin family A member 5
chr2_+_251634431 9.74 ENSRNOT00000045016
dimethylarginine dimethylaminohydrolase 1
chr1_-_219311502 9.73 ENSRNOT00000085439
similar to hypothetical protein MGC37914
chrX_-_139079336 9.52 ENSRNOT00000047605
ubiquitin specific peptidase 26
chr12_+_16913312 9.39 ENSRNOT00000001718
transmembrane protein 184A
chr7_-_124999137 9.39 ENSRNOT00000039228
patatin-like phospholipase domain containing 5
chr2_-_84531192 9.18 ENSRNOT00000065312
ENSRNOT00000090540
rhophilin associated tail protein 1-like
chr2_-_195935878 9.18 ENSRNOT00000028440
cingulin
chr1_-_275876329 9.16 ENSRNOT00000047903
glycerol-3-phosphate acyltransferase, mitochondrial
chr2_-_93641497 9.14 ENSRNOT00000013720
charged multivesicular body protein 4C
chr3_+_56355431 9.11 ENSRNOT00000037188
myosin IIIB
chr10_-_34333305 9.08 ENSRNOT00000071365
olfactory receptor gene Olr1384
chr3_+_143172686 9.06 ENSRNOT00000006869
cystatin 9-like
chr3_+_147511406 8.93 ENSRNOT00000082438
solute carrier family 52 member 3
chr15_+_28028521 8.71 ENSRNOT00000089631

chr10_-_82229140 8.59 ENSRNOT00000004400
epsin 3
chr2_+_242882306 8.40 ENSRNOT00000013661
DNA-damage-inducible transcript 4-like
chr10_+_110346453 8.38 ENSRNOT00000054928
testis expressed 19.1
chr9_+_95233957 8.37 ENSRNOT00000071003
UDP glucuronosyltransferase family 1 member A5
chr13_-_48927483 8.26 ENSRNOT00000010976
cyclin-dependent kinase 18
chr15_-_5509839 8.22 ENSRNOT00000080252
ENSRNOT00000081979
ENSRNOT00000085137
ENSRNOT00000049746
Spetex-2F protein
chr18_-_15225427 8.17 ENSRNOT00000090853
ring finger protein 125
chr1_-_250727079 8.11 ENSRNOT00000079942
ENSRNOT00000087588
sphingomyelin synthase 1
chr3_+_151032952 8.07 ENSRNOT00000064013
acyl-CoA synthetase short-chain family member 2
chr18_-_77579969 8.02 ENSRNOT00000034896
spalt-like transcription factor 3
chr11_+_57404196 8.01 ENSRNOT00000042754
ENSRNOT00000034097
pleckstrin homology-like domain, family B, member 2
chr6_+_111180108 7.92 ENSRNOT00000082027
glutathione S-transferase zeta 1
chr13_+_85580828 7.78 ENSRNOT00000005611
aldehyde dehydrogenase 9 family, member A1
chr4_+_22082194 7.72 ENSRNOT00000091799
carnitine O-octanoyltransferase
chrX_-_40086870 7.65 ENSRNOT00000010027
small muscle protein, X-linked
chr7_-_132143470 7.65 ENSRNOT00000038946
ENSRNOT00000044092
ENSRNOT00000066528
ENSRNOT00000045553
ENSRNOT00000046744
ENSRNOT00000055742
kinesin family member 21A
chr6_-_108120579 7.65 ENSRNOT00000041163
ectonucleoside triphosphate diphosphohydrolase 5
chr10_-_93675991 7.58 ENSRNOT00000090662
membrane associated ring-CH-type finger 10
chr13_-_47377703 7.52 ENSRNOT00000005461
complement component 4 binding protein, alpha
chr8_-_116438038 7.52 ENSRNOT00000023791
G protein subunit alpha transducin 1
chrX_+_13441558 7.51 ENSRNOT00000030170
similar to Ferritin light chain (Ferritin L subunit)
chr6_+_36089433 7.46 ENSRNOT00000090438
ENSRNOT00000005731
5'-nucleotidase, cytosolic IB
chr10_-_46404642 7.43 ENSRNOT00000083698
phosphatidylethanolamine N-methyltransferase
chr1_+_277689729 7.32 ENSRNOT00000051834
von Willebrand factor A domain containing 2
chr5_-_131860637 7.31 ENSRNOT00000064569
ENSRNOT00000080242
solute carrier family 5 member 9
chr1_+_88955135 7.26 ENSRNOT00000083550
proline dehydrogenase 2
chr1_-_71710374 7.19 ENSRNOT00000078556
ENSRNOT00000046152
NLR family, pyrin domain containing 4
chr8_-_70932986 6.97 ENSRNOT00000042353
solute carrier family 51, beta subunit
chr8_+_106449321 6.97 ENSRNOT00000018622
retinol binding protein 1
chr5_+_164845925 6.80 ENSRNOT00000011384
methylenetetrahydrofolate reductase
chr1_+_101397828 6.80 ENSRNOT00000028189
potassium voltage-gated channel subfamily A member 7
chr20_+_4178686 6.73 ENSRNOT00000080641
testis specific basic protein
chr10_+_34185898 6.60 ENSRNOT00000003339
tripartite motif-containing 7
chr2_+_22950018 6.51 ENSRNOT00000071804
homer scaffolding protein 1
chr1_+_150310319 6.47 ENSRNOT00000042081
olfactory receptor 34
chr2_-_188413219 6.40 ENSRNOT00000065065
farnesyl diphosphate synthase
chr16_+_72086878 6.34 ENSRNOT00000023756
ENSRNOT00000078085
ADAM metallopeptidase domain 3A
chr10_-_56412544 6.30 ENSRNOT00000020578
transmembrane protein 102
chr7_+_51794173 6.25 ENSRNOT00000043774
otogelin-like
chr17_-_42127678 6.16 ENSRNOT00000024196
glycosylphosphatidylinositol specific phospholipase D1
chr1_-_219259448 6.16 ENSRNOT00000024517
NADH:ubiquinone oxidoreductase core subunit V1
chr5_-_78042556 6.11 ENSRNOT00000076005

chr8_+_49713190 6.09 ENSRNOT00000022074
FXYD domain-containing ion transport regulator 2
chr11_-_32469566 6.05 ENSRNOT00000002718
similar to RIKEN cDNA 4930563D23
chr8_-_40883880 5.96 ENSRNOT00000075593
disks large homolog 5-like
chr2_-_88660449 5.96 ENSRNOT00000051741
solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr9_+_99795678 5.87 ENSRNOT00000056601
olfactory receptor 1353
chr4_+_180062799 5.86 ENSRNOT00000021623
Ras association domain family member 8
chr6_-_60124274 5.85 ENSRNOT00000059823
leucine-rich single-pass membrane protein 1
chr2_-_192780631 5.85 ENSRNOT00000012371
sperm mitochondria-associated cysteine-rich protein
chr1_-_213921208 5.83 ENSRNOT00000044393
anoctamin 9
chr6_-_39363367 5.75 ENSRNOT00000088687
ENSRNOT00000065531
family with sequence similarity 84, member A
chr10_+_4953879 5.69 ENSRNOT00000003455
transition protein 2
chr16_+_19097391 5.69 ENSRNOT00000018018
calreticulin 3
chr20_-_33322966 5.68 ENSRNOT00000000459
ROS proto-oncogene 1 , receptor tyrosine kinase
chr5_-_171327450 5.68 ENSRNOT00000088710
coiled-coil domain containing 27
chr4_-_117758135 5.55 ENSRNOT00000087750
N-acetyltransferase 8 (GCN5-related) family member 4
chr4_+_120672152 5.54 ENSRNOT00000077231
monoglyceride lipase
chr5_-_77248563 5.53 ENSRNOT00000052243
alpha-2u globulin PGCL5
chr1_-_143392532 5.41 ENSRNOT00000026089
fibronectin type III and SPRY domain containing 2
chr16_-_6077978 5.40 ENSRNOT00000020823
interleukin 17 receptor B
chr3_-_146396299 5.38 ENSRNOT00000040188
ENSRNOT00000008931
adipocyte plasma membrane associated protein
chr1_-_167911961 5.36 ENSRNOT00000025097
olfactory receptor 59
chr19_-_20508711 5.34 ENSRNOT00000032408
hypothetical protein LOC680913
chr1_-_99985422 5.13 ENSRNOT00000025701
kallikrein 1-related peptidase C2
chr1_+_99888297 5.07 ENSRNOT00000080896

chr4_-_117575154 5.02 ENSRNOT00000075813
probable N-acetyltransferase CML2-like
chr5_+_155794229 5.00 ENSRNOT00000018127
hypothetical protein LOC690206
chr4_-_117531480 4.98 ENSRNOT00000021120
N-acetyltransferase 8 (GCN5-related) family member 5
chr7_-_18180705 4.94 ENSRNOT00000065954
zinc finger protein 494
chr6_+_110749705 4.77 ENSRNOT00000084348
leucine rich repeat containing 74A
chr4_-_181348038 4.77 ENSRNOT00000082879
hypothetical protein LOC690783
chr2_-_227207584 4.66 ENSRNOT00000065361
ENSRNOT00000080215
myozenin 2
chr3_+_143151739 4.62 ENSRNOT00000006850
cystatin 13
chrM_+_7758 4.61 ENSRNOT00000046201
mitochondrially encoded ATP synthase 8
chr10_-_10807079 4.54 ENSRNOT00000087029
similar to hypothetical protein
chr15_-_12262164 4.48 ENSRNOT00000008798
olfactory receptor 1606
chr8_+_84945444 4.48 ENSRNOT00000008244
kelch-like family member 31
chr1_-_206394346 4.45 ENSRNOT00000038122
hypothetical LOC100302465
chr10_+_57064482 4.34 ENSRNOT00000046807
zinc finger, MYND-type containing 15
chr15_-_47442664 4.34 ENSRNOT00000072994
protease, serine, 55
chr19_+_683484 4.33 ENSRNOT00000090332
telomere repeat binding bouquet formation protein 1
chr9_+_51009116 4.30 ENSRNOT00000039313
methyltransferase like 21C-like 1
chr5_+_126334803 4.30 ENSRNOT00000010288
family with sequence similarity 151, member A
chr17_+_16340226 4.28 ENSRNOT00000089140
protein tyrosine phosphatase domain containing 1
chrX_-_42329232 4.28 ENSRNOT00000045705
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 4
chr2_+_154921999 4.27 ENSRNOT00000057620
similar to GTPase activating protein testicular GAP1
chr9_+_24066303 4.23 ENSRNOT00000018163
cysteine-rich secretory protein 3
chr10_-_90410569 4.19 ENSRNOT00000036112
integrin subunit alpha 2b
chr3_-_120011364 4.19 ENSRNOT00000018922
fumarylacetoacetate hydrolase domain containing 2A
chr4_-_27698037 4.17 ENSRNOT00000038136
peroxisomal biogenesis factor 1
chrX_+_115721251 4.11 ENSRNOT00000060090
TRPC5 opposite strand
chr10_+_88992487 4.10 ENSRNOT00000027061
Coenzyme A synthase
chr15_+_28050975 4.07 ENSRNOT00000050944
epididymal secretory protein E3-beta-like
chr2_-_260108897 4.07 ENSRNOT00000014106
mutS homolog 4
chr9_+_93445002 4.03 ENSRNOT00000025029
similar to hypothetical protein MGC35154
chr10_+_63677396 4.00 ENSRNOT00000005100
solute carrier family 43 member 2
chr1_-_12952906 3.96 ENSRNOT00000078193
hypothetical protein LOC100360362
chr1_-_82452281 3.96 ENSRNOT00000027995
branched chain ketoacid dehydrogenase E1, alpha polypeptide
chr4_+_52199416 3.92 ENSRNOT00000009537
sperm adhesion molecule 1
chrM_+_11736 3.91 ENSRNOT00000048767
mitochondrially encoded NADH dehydrogenase 5
chr14_+_77079402 3.91 ENSRNOT00000042200
solute carrier family 2 member 9
chr6_+_52702544 3.86 ENSRNOT00000014252
EF-hand calcium binding domain 10
chr13_+_88286718 3.85 ENSRNOT00000046076
Da1-10-like
chr15_-_12129220 3.83 ENSRNOT00000029318
olfactory receptor 1605
chr9_-_104467973 3.81 ENSRNOT00000026099
solute carrier organic anion transporter family member 6B1
chr1_+_83573032 3.77 ENSRNOT00000083650

chr8_-_72842228 3.76 ENSRNOT00000090288
tropomyosin 1, alpha
chr12_+_24761210 3.74 ENSRNOT00000002003
claudin 4
chr18_-_81682206 3.70 ENSRNOT00000058219
hypothetical protein LOC100359752
chr15_-_28092023 3.67 ENSRNOT00000090835
epididymal protein 3B
chr3_+_15749691 3.67 ENSRNOT00000030984
olfactory receptor 396
chr10_-_87954055 3.62 ENSRNOT00000018048
keratin 34
chr8_-_132790778 3.58 ENSRNOT00000008255
ENSRNOT00000091431
leucine zipper transcription factor-like 1
chr14_+_60657686 3.55 ENSRNOT00000070892
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
chr3_-_52361060 3.54 ENSRNOT00000007832
tetratricopeptide repeat domain 21B
chr8_-_90962470 3.50 ENSRNOT00000086426
LCA5, lebercilin

Network of associatons between targets according to the STRING database.

First level regulatory network of Mafb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
10.1 30.3 GO:0046340 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) diacylglycerol catabolic process(GO:0046340)
9.1 72.9 GO:1902222 L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
6.5 32.4 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
5.2 25.8 GO:0072240 DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240)
4.7 23.6 GO:0035106 operant conditioning(GO:0035106)
4.4 13.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
4.0 19.8 GO:0015793 glycerol transport(GO:0015793)
3.6 21.6 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
3.4 10.2 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
3.4 27.1 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
3.2 34.8 GO:0015747 urate transport(GO:0015747)
3.1 6.2 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
3.0 8.9 GO:0032218 riboflavin transport(GO:0032218)
2.9 14.7 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
2.7 13.7 GO:0008295 spermidine biosynthetic process(GO:0008295)
2.7 8.1 GO:0006083 acetate metabolic process(GO:0006083)
2.5 7.5 GO:0045959 negative regulation of complement activation, classical pathway(GO:0045959)
2.4 7.3 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
2.4 9.8 GO:0061107 seminal vesicle development(GO:0061107)
2.4 7.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
2.4 16.7 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
2.3 9.4 GO:0018992 germ-line sex determination(GO:0018992)
2.3 13.9 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
2.3 9.1 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
2.2 15.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
2.2 10.9 GO:0061709 reticulophagy(GO:0061709)
2.1 10.4 GO:0000066 mitochondrial ornithine transport(GO:0000066)
1.9 5.8 GO:2001226 negative regulation of inorganic anion transmembrane transport(GO:1903796) negative regulation of chloride transport(GO:2001226)
1.9 7.7 GO:0001579 medium-chain fatty acid transport(GO:0001579)
1.8 11.1 GO:0006069 ethanol oxidation(GO:0006069)
1.8 5.4 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
1.7 17.5 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
1.6 11.5 GO:0007341 penetration of zona pellucida(GO:0007341)
1.5 18.0 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
1.4 18.7 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
1.4 5.5 GO:2000124 endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
1.4 8.3 GO:0070827 chromatin maintenance(GO:0070827)
1.3 14.5 GO:0030049 muscle filament sliding(GO:0030049)
1.3 6.4 GO:0033384 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384)
1.3 7.5 GO:0050917 sensory perception of umami taste(GO:0050917) positive regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051343)
1.2 8.4 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
1.2 15.5 GO:0001778 plasma membrane repair(GO:0001778)
1.2 15.3 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857)
1.2 5.9 GO:0034334 adherens junction maintenance(GO:0034334)
1.2 8.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
1.1 3.4 GO:0006649 phospholipid transfer to membrane(GO:0006649)
1.1 5.4 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664)
1.0 3.1 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589)
1.0 9.2 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
1.0 14.9 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.9 5.7 GO:0010966 regulation of phosphate transport(GO:0010966)
0.9 8.4 GO:0052697 xenobiotic glucuronidation(GO:0052697)
0.9 10.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.9 3.6 GO:1903564 regulation of protein localization to cilium(GO:1903564)
0.9 7.0 GO:0006776 vitamin A metabolic process(GO:0006776)
0.8 9.7 GO:0006527 arginine catabolic process(GO:0006527)
0.8 3.2 GO:0072092 ureteric bud invasion(GO:0072092)
0.8 2.4 GO:0006710 androgen catabolic process(GO:0006710)
0.7 30.6 GO:0042311 vasodilation(GO:0042311)
0.7 5.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.7 8.1 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.7 10.0 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.7 2.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.7 7.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.7 3.4 GO:0001552 ovarian follicle atresia(GO:0001552)
0.7 11.2 GO:0019532 oxalate transport(GO:0019532) sulfate transmembrane transport(GO:1902358)
0.6 6.3 GO:0019321 pentose metabolic process(GO:0019321)
0.6 2.5 GO:2000304 cardiolipin acyl-chain remodeling(GO:0035965) positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.6 6.8 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.6 1.2 GO:1904404 response to formaldehyde(GO:1904404)
0.6 1.8 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.6 0.6 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.6 7.6 GO:0045821 positive regulation of glycolytic process(GO:0045821)
0.6 34.7 GO:0030239 myofibril assembly(GO:0030239)
0.5 9.2 GO:0048240 sperm capacitation(GO:0048240)
0.5 13.6 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.5 2.4 GO:0045006 DNA deamination(GO:0045006)
0.5 1.9 GO:1900625 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) positive regulation of hyaluronan biosynthetic process(GO:1900127) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.5 14.6 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.4 2.2 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.4 8.0 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.4 3.5 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.4 6.5 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.4 2.1 GO:0046110 xanthine catabolic process(GO:0009115) xanthine metabolic process(GO:0046110)
0.4 2.5 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.4 2.4 GO:0072014 proximal tubule development(GO:0072014)
0.4 1.9 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.4 8.0 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.4 12.6 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.4 1.5 GO:2000551 regulation of T-helper 2 cell cytokine production(GO:2000551)
0.4 6.1 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.4 2.5 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.4 3.5 GO:0035721 forebrain dorsal/ventral pattern formation(GO:0021798) intraciliary retrograde transport(GO:0035721)
0.4 1.8 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.3 1.7 GO:0031296 B cell costimulation(GO:0031296)
0.3 1.0 GO:0051012 microtubule sliding(GO:0051012)
0.3 3.9 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.3 1.3 GO:1901318 negative regulation of sperm motility(GO:1901318)
0.3 8.7 GO:0019433 triglyceride catabolic process(GO:0019433)
0.3 4.0 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.3 6.1 GO:0006829 zinc II ion transport(GO:0006829)
0.3 1.4 GO:0019563 glycerol catabolic process(GO:0019563)
0.3 0.8 GO:0044726 protection of DNA demethylation of female pronucleus(GO:0044726)
0.3 0.8 GO:0042938 dipeptide transport(GO:0042938)
0.3 0.8 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.3 1.8 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.3 6.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.3 6.3 GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901028)
0.2 4.2 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.2 4.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.2 8.2 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.2 0.7 GO:0021997 neural plate axis specification(GO:0021997)
0.2 0.4 GO:0070368 positive regulation of hepatocyte differentiation(GO:0070368)
0.2 8.2 GO:1901998 toxin transport(GO:1901998)
0.2 2.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 9.1 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.2 10.1 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.2 1.9 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.2 52.7 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.2 0.4 GO:2000017 regulation of determination of dorsal identity(GO:2000015) positive regulation of determination of dorsal identity(GO:2000017)
0.2 0.8 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.2 1.0 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.2 3.1 GO:0030048 actin filament-based movement(GO:0030048)
0.2 1.8 GO:0003334 keratinocyte development(GO:0003334)
0.2 1.9 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.2 4.6 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 4.5 GO:0031572 mitotic G2 DNA damage checkpoint(GO:0007095) G2 DNA damage checkpoint(GO:0031572)
0.2 3.0 GO:0021984 spinal cord association neuron differentiation(GO:0021527) adenohypophysis development(GO:0021984)
0.2 1.6 GO:0015886 heme transport(GO:0015886)
0.2 1.0 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.2 9.2 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.2 1.3 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 3.5 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 0.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.1 0.6 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 1.7 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.1 3.0 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 16.0 GO:0006818 hydrogen transport(GO:0006818)
0.1 1.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 2.7 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 0.6 GO:0006553 lysine metabolic process(GO:0006553)
0.1 5.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.6 GO:0006983 ER overload response(GO:0006983)
0.1 0.4 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 0.8 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.1 1.9 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 2.0 GO:0045475 locomotor rhythm(GO:0045475)
0.1 2.1 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.1 0.9 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.9 GO:0070307 lens fiber cell development(GO:0070307)
0.1 2.9 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 3.0 GO:0050912 detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.1 1.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 101.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 2.0 GO:0042073 intraciliary transport(GO:0042073)
0.1 0.8 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.1 1.2 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 1.5 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.1 0.9 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.4 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 12.7 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.1 0.3 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.1 2.3 GO:0006505 GPI anchor metabolic process(GO:0006505)
0.1 7.8 GO:0007605 sensory perception of sound(GO:0007605)
0.1 0.3 GO:0010046 response to mycotoxin(GO:0010046)
0.1 6.4 GO:0006821 chloride transport(GO:0006821)
0.1 0.4 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1 0.5 GO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress(GO:0036003)
0.1 1.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.4 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.1 0.2 GO:0033026 negative regulation of mast cell apoptotic process(GO:0033026)
0.1 0.6 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 7.3 GO:0007369 gastrulation(GO:0007369)
0.1 6.7 GO:0090501 RNA phosphodiester bond hydrolysis(GO:0090501)
0.0 2.5 GO:0006094 gluconeogenesis(GO:0006094)
0.0 0.3 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 2.0 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 1.2 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 4.3 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 10.7 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.0 0.3 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.9 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 3.9 GO:0006941 striated muscle contraction(GO:0006941)
0.0 2.1 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.1 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.0 0.2 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.9 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.3 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.0 1.6 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 2.1 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.3 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 1.0 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 2.2 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.4 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 30.3 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
1.9 9.6 GO:0043159 acrosomal matrix(GO:0043159)
1.7 15.5 GO:0005826 actomyosin contractile ring(GO:0005826)
1.5 7.6 GO:0005927 muscle tendon junction(GO:0005927)
1.4 9.8 GO:0031094 platelet dense tubular network(GO:0031094)
1.4 4.1 GO:0005713 recombination nodule(GO:0005713) MutSalpha complex(GO:0032301)
1.3 9.1 GO:0090543 Flemming body(GO:0090543)
0.9 8.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.9 8.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.8 4.0 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.7 9.1 GO:0032426 stereocilium tip(GO:0032426)
0.6 13.4 GO:0005922 connexon complex(GO:0005922)
0.6 2.5 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.6 52.5 GO:0031526 brush border membrane(GO:0031526)
0.6 8.2 GO:0032982 myosin filament(GO:0032982)
0.5 3.8 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.5 3.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.5 6.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.5 3.5 GO:0030991 intraciliary transport particle A(GO:0030991)
0.5 1.5 GO:0045025 mitochondrial degradosome(GO:0045025)
0.4 4.3 GO:0070187 telosome(GO:0070187)
0.4 6.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.4 8.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.4 18.6 GO:0016459 myosin complex(GO:0016459)
0.4 4.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.3 10.9 GO:0034451 centriolar satellite(GO:0034451)
0.3 38.0 GO:0072562 blood microparticle(GO:0072562)
0.3 2.5 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.3 44.0 GO:0030018 Z disc(GO:0030018)
0.3 5.5 GO:0043196 varicosity(GO:0043196)
0.3 1.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3 18.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.3 27.7 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.3 1.5 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.3 4.0 GO:0045180 basal cortex(GO:0045180)
0.2 1.0 GO:0005606 laminin-1 complex(GO:0005606)
0.2 0.9 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.2 29.8 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.2 11.3 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 8.0 GO:0001917 photoreceptor inner segment(GO:0001917)
0.2 116.4 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.2 2.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 9.4 GO:0005811 lipid particle(GO:0005811)
0.2 2.7 GO:0071437 invadopodium(GO:0071437)
0.1 3.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 49.6 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 8.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 2.2 GO:0042599 lamellar body(GO:0042599)
0.1 3.3 GO:0001533 cornified envelope(GO:0001533)
0.1 2.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 3.9 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.9 GO:0002177 manchette(GO:0002177)
0.1 5.8 GO:0031901 early endosome membrane(GO:0031901)
0.1 20.1 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 2.1 GO:0005605 basal lamina(GO:0005605)
0.1 1.3 GO:0044292 dendrite terminus(GO:0044292)
0.1 0.5 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.8 GO:0005903 brush border(GO:0005903)
0.1 0.5 GO:0000800 lateral element(GO:0000800)
0.1 6.6 GO:0005882 intermediate filament(GO:0005882)
0.1 1.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.9 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 6.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 4.7 GO:0005923 bicellular tight junction(GO:0005923)
0.0 97.5 GO:1903561 extracellular vesicle(GO:1903561)
0.0 3.5 GO:0036064 ciliary basal body(GO:0036064)
0.0 2.6 GO:0031514 motile cilium(GO:0031514)
0.0 0.2 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 2.2 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 0.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 1.9 GO:0005769 early endosome(GO:0005769)
0.0 0.8 GO:0005884 actin filament(GO:0005884)
0.0 55.5 GO:0016021 integral component of membrane(GO:0016021)
0.0 0.5 GO:0005844 polysome(GO:0005844)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
14.4 43.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
10.1 30.3 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
9.6 28.9 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
7.5 37.3 GO:0051373 FATZ binding(GO:0051373)
5.6 22.5 GO:0003987 acetate-CoA ligase activity(GO:0003987)
4.6 13.9 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
3.9 38.7 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
3.4 27.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
3.2 9.7 GO:0016403 dimethylargininase activity(GO:0016403)
3.2 32.4 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
3.0 8.9 GO:0032217 riboflavin transporter activity(GO:0032217)
2.6 7.7 GO:0016414 carnitine O-octanoyltransferase activity(GO:0008458) O-octanoyltransferase activity(GO:0016414)
2.6 17.9 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
2.4 9.8 GO:0032190 acrosin binding(GO:0032190)
2.4 7.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
1.9 7.6 GO:0045134 uridine-diphosphatase activity(GO:0045134)
1.6 8.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
1.5 9.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
1.4 19.8 GO:0015250 water channel activity(GO:0015250)
1.4 13.7 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
1.3 5.4 GO:0004064 arylesterase activity(GO:0004064)
1.3 10.4 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
1.3 6.5 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
1.3 6.4 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
1.3 10.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
1.0 10.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
1.0 30.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
1.0 27.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
1.0 15.3 GO:0035497 cAMP response element binding(GO:0035497)
0.9 20.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.9 2.8 GO:0031763 galanin receptor binding(GO:0031763) type 2 galanin receptor binding(GO:0031765) type 3 galanin receptor binding(GO:0031766)
0.9 18.7 GO:0008199 ferric iron binding(GO:0008199)
0.9 32.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.8 2.5 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.8 4.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.8 17.4 GO:0000146 microfilament motor activity(GO:0000146)
0.8 2.4 GO:0035939 microsatellite binding(GO:0035939)
0.8 7.0 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.8 7.0 GO:0019841 retinol binding(GO:0019841)
0.8 6.2 GO:0004630 phospholipase D activity(GO:0004630)
0.8 3.0 GO:0055100 adiponectin binding(GO:0055100)
0.7 11.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.7 7.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.7 5.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.7 7.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.7 4.2 GO:0070051 fibrinogen binding(GO:0070051)
0.7 3.4 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.7 49.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.6 14.9 GO:0071837 HMG box domain binding(GO:0071837)
0.6 7.8 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.6 5.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.5 14.7 GO:0008483 transaminase activity(GO:0008483)
0.5 15.3 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.5 2.1 GO:0004031 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.5 3.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.5 14.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.5 2.1 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.5 54.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.5 2.4 GO:0004969 histamine receptor activity(GO:0004969)
0.5 3.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.5 9.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.5 6.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.5 1.4 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.5 10.2 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.5 1.9 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.5 1.8 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.4 3.1 GO:0030881 beta-2-microglobulin binding(GO:0030881) transferrin receptor binding(GO:1990459)
0.4 1.8 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.4 4.0 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.4 7.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.4 7.5 GO:0001848 complement binding(GO:0001848)
0.4 3.9 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.4 6.8 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.4 3.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.4 10.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.4 1.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.3 9.2 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.3 1.8 GO:0016918 retinal binding(GO:0016918)
0.3 2.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.3 0.8 GO:0015322 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.3 2.5 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.3 0.8 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.3 1.5 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.3 1.0 GO:0019862 IgA binding(GO:0019862)
0.2 18.1 GO:0038024 cargo receptor activity(GO:0038024)
0.2 3.4 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.2 0.7 GO:0005119 smoothened binding(GO:0005119)
0.2 6.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.2 19.3 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.2 1.5 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.2 8.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 1.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.2 5.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.2 2.0 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 10.8 GO:0017046 peptide hormone binding(GO:0017046)
0.2 1.6 GO:0015232 heme transporter activity(GO:0015232)
0.2 2.9 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 2.1 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 3.2 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.2 31.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 16.3 GO:0004540 ribonuclease activity(GO:0004540)
0.1 0.6 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 11.6 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.1 4.1 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.8 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.6 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 1.0 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 1.2 GO:0008527 taste receptor activity(GO:0008527)
0.1 46.5 GO:0005549 odorant binding(GO:0005549)
0.1 12.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 3.4 GO:0051393 alpha-actinin binding(GO:0051393)
0.1 5.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 2.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 8.9 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)
0.1 0.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 5.7 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 0.6 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.1 2.2 GO:0050681 androgen receptor binding(GO:0050681)
0.1 6.9 GO:0051082 unfolded protein binding(GO:0051082)
0.1 1.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.2 GO:0005135 interleukin-3 receptor binding(GO:0005135)
0.1 61.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 1.5 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 3.7 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.1 2.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.4 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 3.4 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 2.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 4.4 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 6.6 GO:0016874 ligase activity(GO:0016874)
0.0 0.9 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.0 1.3 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.1 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 4.0 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 8.7 GO:0045296 cadherin binding(GO:0045296)
0.0 2.4 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 2.3 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 2.6 GO:0030165 PDZ domain binding(GO:0030165)
0.0 2.1 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.1 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 35.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.4 17.9 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.3 75.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.3 8.0 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.2 7.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.2 7.5 PID CD40 PATHWAY CD40/CD40L signaling
0.2 5.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 3.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.2 5.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 1.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 1.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 4.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 2.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 2.1 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 40.8 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
4.7 46.8 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
1.8 30.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
1.5 30.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
1.2 15.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.7 7.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.6 23.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.6 10.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.6 10.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.6 7.7 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.5 7.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.5 19.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.5 11.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.5 9.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.4 8.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.4 9.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.4 7.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.4 78.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.4 4.7 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.3 14.3 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.3 4.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.3 8.0 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.3 3.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.3 9.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.3 1.5 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.3 6.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 8.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2 4.2 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2 10.0 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.2 8.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 1.8 REACTOME OPSINS Genes involved in Opsins
0.2 7.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.2 10.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.2 2.3 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 2.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 6.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 3.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 8.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 7.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 3.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 2.3 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 1.2 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.1 2.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 3.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 0.9 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 1.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 2.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 2.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.3 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 0.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation