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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Lhx3

Z-value: 0.53

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Transcription factors associated with Lhx3

Gene Symbol Gene ID Gene Info
Lhx3
ENSRNOG00000018427 LIM homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Lhx3rn6_v1_chr3_-_3661810_36618100.099.4e-02Click!

Activity profile of Lhx3 motif

Sorted Z-values of Lhx3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_71139267 46.40 ENSRNOT00000065232
RGD1561812
similar to Retinol dehydrogenase type II (RODH II) (29 k-protein)
chr3_+_159368273 23.84 ENSRNOT00000041688
Sgk2
serum/glucocorticoid regulated kinase 2
chr18_+_59748444 20.35 ENSRNOT00000024752
St8sia3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr10_+_103206014 17.89 ENSRNOT00000004081
Ttyh2
tweety family member 2
chr11_+_36851038 15.57 ENSRNOT00000002221
ENSRNOT00000061047
Pcp4
Purkinje cell protein 4
chr6_+_64789940 14.17 ENSRNOT00000085979
ENSRNOT00000059739
ENSRNOT00000051908
ENSRNOT00000082793
ENSRNOT00000078583
ENSRNOT00000091677
ENSRNOT00000093241
Nrcam
neuronal cell adhesion molecule
chr15_-_93307420 13.89 ENSRNOT00000012195
Slitrk1
SLIT and NTRK-like family, member 1
chr2_+_54466280 13.48 ENSRNOT00000033112
C6
complement C6
chr13_+_47572219 13.03 ENSRNOT00000088449
ENSRNOT00000087664
ENSRNOT00000005853
Pigr
polymeric immunoglobulin receptor
chr8_-_7426611 11.95 ENSRNOT00000031492
Arhgap42
Rho GTPase activating protein 42
chr9_+_73418607 11.95 ENSRNOT00000092547
Map2
microtubule-associated protein 2
chr9_+_73378057 11.17 ENSRNOT00000043627
ENSRNOT00000045766
ENSRNOT00000092445
ENSRNOT00000037974
Map2
microtubule-associated protein 2
chr5_+_124442293 11.07 ENSRNOT00000041922
RGD1564074
similar to novel protein
chr14_+_39964588 10.81 ENSRNOT00000003240
Gabrg1
gamma-aminobutyric acid type A receptor gamma 1 subunit
chr7_-_105592804 10.76 ENSRNOT00000006789
Adcy8
adenylate cyclase 8
chr1_+_238222521 10.70 ENSRNOT00000024000
Aldh1a1
aldehyde dehydrogenase 1 family, member A1
chr13_+_84474319 10.61 ENSRNOT00000031367
ENSRNOT00000072244
ENSRNOT00000072897
ENSRNOT00000064168
ENSRNOT00000074954
ENSRNOT00000073696
Ildr2
immunoglobulin-like domain containing receptor 2
chr20_+_34258791 10.27 ENSRNOT00000000468
Slc35f1
solute carrier family 35, member F1
chr6_+_48452369 9.23 ENSRNOT00000044310
Myt1l
myelin transcription factor 1-like
chr20_-_4542073 8.61 ENSRNOT00000000477
Cfb
complement factor B
chr14_-_84334066 8.23 ENSRNOT00000006160
Mtfp1
mitochondrial fission process 1
chr4_-_55011415 7.92 ENSRNOT00000056996
Grm8
glutamate metabotropic receptor 8
chr6_+_2216623 7.89 ENSRNOT00000008045
Rmdn2
regulator of microtubule dynamics 2
chrX_+_151103576 7.55 ENSRNOT00000015401
Slitrk2
SLIT and NTRK-like family, member 2
chr3_-_67787990 7.04 ENSRNOT00000064851
Nckap1
NCK-associated protein 1
chr13_-_76049363 6.45 ENSRNOT00000075865
ENSRNOT00000007455
Brinp2
BMP/retinoic acid inducible neural specific 2
chr16_+_23447366 6.36 ENSRNOT00000068629
Psd3
pleckstrin and Sec7 domain containing 3
chr2_-_181900856 6.13 ENSRNOT00000082156
Lrat
lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)
chr15_+_59678165 5.81 ENSRNOT00000074868
Enox1
ecto-NOX disulfide-thiol exchanger 1
chr18_+_16146447 5.81 ENSRNOT00000022117
Galnt1
polypeptide N-acetylgalactosaminyltransferase 1
chr17_-_89923423 5.67 ENSRNOT00000076964
Acbd5
acyl-CoA binding domain containing 5
chrX_+_20520034 5.39 ENSRNOT00000093170
FAM120C
family with sequence similarity 120C
chr12_-_2174131 4.92 ENSRNOT00000001313
Pcp2
Purkinje cell protein 2
chr12_+_41486076 4.32 ENSRNOT00000057242
Rita1
RBPJ interacting and tubulin associated 1
chr10_+_53778662 4.31 ENSRNOT00000045718
Myh2
myosin heavy chain 2
chr1_-_264975132 4.21 ENSRNOT00000021748
Lbx1
ladybird homeobox 1
chr9_-_88086488 4.06 ENSRNOT00000019579
Irs1
insulin receptor substrate 1
chr7_+_44009069 4.06 ENSRNOT00000005523
Mgat4c
MGAT4 family, member C
chrX_-_29648359 3.87 ENSRNOT00000086721
ENSRNOT00000006777
Gpm6b
glycoprotein m6b
chr11_-_68989988 3.61 ENSRNOT00000003013
Hacd2
3-hydroxyacyl-CoA dehydratase 2
chr1_+_185863043 3.42 ENSRNOT00000079072
Sox6
SRY box 6
chr5_+_6373583 3.11 ENSRNOT00000084749
AABR07046778.1

chr14_-_21909646 3.05 ENSRNOT00000088024
Csn1s2b
casein alpha s2-like B
chr12_-_46493203 3.01 ENSRNOT00000057036
Cit
citron rho-interacting serine/threonine kinase
chr6_-_142418779 3.00 ENSRNOT00000072280
ENSRNOT00000065808
AABR07065814.1

chr18_+_29993361 2.99 ENSRNOT00000075810
Pcdha4
protocadherin alpha 4
chr10_-_34301197 2.97 ENSRNOT00000044667
Olr1383
olfactory receptor 1383
chr18_-_43945273 2.89 ENSRNOT00000088900
Dtwd2
DTW domain containing 2
chrX_-_111191932 2.86 ENSRNOT00000088050
ENSRNOT00000083613
Morc4
MORC family CW-type zinc finger 4
chr20_-_13994794 2.84 ENSRNOT00000093466
Ggt5
gamma-glutamyltransferase 5
chr2_+_30685840 2.80 ENSRNOT00000031385
Ccdc125
coiled-coil domain containing 125
chr8_-_43524220 2.63 ENSRNOT00000088755
Olr1315
olfactory receptor 1315
chrM_+_9870 2.46 ENSRNOT00000044582
Mt-nd4l
mitochondrially encoded NADH 4L dehydrogenase
chrX_+_14019961 2.44 ENSRNOT00000004785
Sytl5
synaptotagmin-like 5
chr2_-_233743866 2.34 ENSRNOT00000087062
Enpep
glutamyl aminopeptidase
chr11_-_11585078 2.26 ENSRNOT00000088878
Robo2
roundabout guidance receptor 2
chrX_-_124252447 2.23 ENSRNOT00000061546
Rhox12
reproductive homeobox 12
chr6_+_18880737 2.10 ENSRNOT00000003432
Alkbh8
alkB homolog 8, tRNA methyltransferase
chr2_-_149444548 2.05 ENSRNOT00000018600
P2ry12
purinergic receptor P2Y12
chr1_+_79631668 2.02 ENSRNOT00000083546
ENSRNOT00000035286
Mill1
MHC I like leukocyte 1
chr15_-_46166335 1.93 ENSRNOT00000059215
Defb42
defensin beta 42
chr14_+_7026769 1.89 ENSRNOT00000071955
LOC100359907
secretory calcium-binding phosphoprotein proline-glutamine rich 1-like
chr2_+_145174876 1.63 ENSRNOT00000040631
Mab21l1
mab-21 like 1
chr3_+_119561290 1.59 ENSRNOT00000015843
Blvra
biliverdin reductase A
chr2_-_35550204 1.57 ENSRNOT00000084377
Olr1280
olfactory receptor 1280
chr10_+_67810810 1.56 ENSRNOT00000079156
Psmd11
proteasome 26S subunit, non-ATPase 11
chr8_-_44565861 1.48 ENSRNOT00000049921
AABR07069997.1

chr15_+_27438853 1.37 ENSRNOT00000011636
Olr1622
olfactory receptor 1622
chr2_+_226563050 1.36 ENSRNOT00000065111
Bcar3
breast cancer anti-estrogen resistance 3
chr1_-_813517 1.24 ENSRNOT00000041332
Vom2r5
vomeronasal 2 receptor, 5
chr16_-_75241303 1.24 ENSRNOT00000058056
Defb2
defensin beta 2
chr9_-_121725716 1.02 ENSRNOT00000087405
Adcyap1
adenylate cyclase activating polypeptide 1
chr8_+_19888667 0.93 ENSRNOT00000078593
Zfp317
zinc finger protein 317
chr14_-_1785698 0.92 ENSRNOT00000071182
Vom2r73
vomeronasal 2 receptor, 73
chr1_+_230628996 0.90 ENSRNOT00000017604
Olr376
olfactory receptor 376
chr18_-_36322320 0.82 ENSRNOT00000060260
Grxcr2
glutaredoxin and cysteine rich domain containing 2
chr1_+_22319353 0.80 ENSRNOT00000038523
Taar9
trace amine-associated receptor 9
chr14_-_24123253 0.80 ENSRNOT00000002743
Tmprss11b
transmembrane protease, serine 11B
chr15_-_54528480 0.76 ENSRNOT00000066888
Fndc3a
fibronectin type III domain containing 3a
chrM_+_9451 0.74 ENSRNOT00000041241
Mt-nd3
mitochondrially encoded NADH dehydrogenase 3
chr1_-_69016426 0.73 ENSRNOT00000093436
Vom2r3

chr10_+_67810655 0.73 ENSRNOT00000064285
Psmd11
proteasome 26S subunit, non-ATPase 11
chr2_+_239415046 0.63 ENSRNOT00000072196
Cxxc4
CXXC finger protein 4
chrX_+_112311251 0.63 ENSRNOT00000086698
AABR07040855.1

chr14_+_23405717 0.60 ENSRNOT00000029805
Tmprss11c
transmembrane protease, serine 11C
chr2_-_198706428 0.60 ENSRNOT00000085006
Polr3gl
RNA polymerase III subunit G like
chr11_-_43594659 0.58 ENSRNOT00000086976
Olr1555
olfactory receptor 1555
chr3_+_77289805 0.57 ENSRNOT00000040581
LOC100910858
olfactory receptor 4P4-like
chr8_+_117297670 0.51 ENSRNOT00000082628
Qars
glutaminyl-tRNA synthetase
chrX_-_120521871 0.50 ENSRNOT00000080863
LOC100362376
LRRGT00025-like
chr14_+_36047144 0.39 ENSRNOT00000003088
Lnx1
ligand of numb-protein X 1
chr3_+_76052230 0.16 ENSRNOT00000039963
LOC100911380
olfactory receptor 5W2-like
chr15_+_35889080 0.15 ENSRNOT00000075355
LOC100910640
olfactory receptor 144-like
chr10_+_112056994 0.11 ENSRNOT00000073032
Vom2r65
vomeronasal 2 receptor, 65
chr10_-_60032218 0.11 ENSRNOT00000072328
Olr1481
olfactory receptor 1481

Network of associatons between targets according to the STRING database.

First level regulatory network of Lhx3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.8 20.4 GO:1990743 protein sialylation(GO:1990743)
4.5 13.5 GO:0001969 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
4.3 13.0 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
4.0 12.0 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
3.9 15.6 GO:1904009 cellular response to monosodium glutamate(GO:1904009)
1.6 14.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
1.4 5.7 GO:0030242 pexophagy(GO:0030242)
1.4 7.0 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
1.3 10.7 GO:0042905 optic cup morphogenesis involved in camera-type eye development(GO:0002072) 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
1.2 5.8 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.9 8.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.8 4.1 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
0.8 3.9 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.8 6.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.7 7.9 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.7 2.1 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.7 3.4 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.6 4.9 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.6 23.1 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.5 2.0 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.5 2.3 GO:0002003 angiotensin maturation(GO:0002003)
0.5 2.3 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.4 4.2 GO:0048664 neuron fate determination(GO:0048664)
0.4 2.8 GO:0006751 glutathione catabolic process(GO:0006751)
0.3 4.3 GO:0001778 plasma membrane repair(GO:0001778)
0.3 1.6 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.3 6.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.3 10.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.3 1.0 GO:0002877 regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
0.2 3.6 GO:0030497 fatty acid elongation(GO:0030497)
0.2 20.0 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.2 10.8 GO:0007616 long-term memory(GO:0007616)
0.2 10.6 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.2 2.1 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.2 23.8 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.2 11.1 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.2 16.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.2 8.2 GO:0000266 mitochondrial fission(GO:0000266)
0.1 3.0 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 2.3 GO:0043248 proteasome assembly(GO:0043248)
0.1 3.8 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 6.5 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.7 GO:0009642 response to light intensity(GO:0009642)
0.1 1.4 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 0.6 GO:0097264 self proteolysis(GO:0097264)
0.0 2.5 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 2.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 2.9 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 3.0 GO:0042476 odontogenesis(GO:0042476)
0.0 0.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.5 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 23.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
1.9 13.5 GO:0005579 membrane attack complex(GO:0005579)
1.4 4.1 GO:0005899 insulin receptor complex(GO:0005899)
1.0 15.6 GO:0005883 neurofilament(GO:0005883)
0.8 7.0 GO:0031209 SCAR complex(GO:0031209)
0.5 14.2 GO:0043194 axon initial segment(GO:0043194)
0.5 28.7 GO:0034707 chloride channel complex(GO:0034707)
0.5 4.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.4 20.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.3 11.1 GO:0001772 immunological synapse(GO:0001772)
0.3 2.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.3 13.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 4.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 2.3 GO:0031983 vesicle lumen(GO:0031983)
0.2 6.1 GO:0005771 multivesicular body(GO:0005771)
0.1 2.0 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 2.3 GO:0030673 axolemma(GO:0030673)
0.1 8.8 GO:0031985 Golgi cisterna(GO:0031985)
0.1 5.7 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 7.9 GO:0042734 presynaptic membrane(GO:0042734)
0.1 8.6 GO:0072562 blood microparticle(GO:0072562)
0.1 3.2 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 7.9 GO:0000922 spindle pole(GO:0000922)
0.0 0.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 2.1 GO:0005901 caveola(GO:0005901)
0.0 3.9 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 9.3 GO:0043025 neuronal cell body(GO:0043025)
0.0 8.2 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 15.8 GO:0045202 synapse(GO:0045202)
0.0 0.8 GO:0005902 microvillus(GO:0005902)
0.0 4.2 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.8 20.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
3.6 10.7 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
2.0 7.9 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
1.3 23.8 GO:0017081 chloride channel regulator activity(GO:0017081)
1.2 9.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
1.0 9.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
1.0 23.1 GO:0002162 dystroglycan binding(GO:0002162)
0.9 10.3 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.8 4.5 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.7 3.6 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812)
0.6 10.8 GO:0050811 GABA receptor binding(GO:0050811)
0.5 5.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.5 2.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.5 4.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.5 2.8 GO:0036374 gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.5 6.1 GO:0019841 retinol binding(GO:0019841)
0.4 3.0 GO:0035375 zymogen binding(GO:0035375)
0.3 2.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.3 6.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 5.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.2 2.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 16.1 GO:0005254 chloride channel activity(GO:0005254)
0.1 7.0 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 3.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 2.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 16.9 GO:0030695 GTPase regulator activity(GO:0030695)
0.1 11.4 GO:0005516 calmodulin binding(GO:0005516)
0.1 1.6 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 3.0 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 1.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.8 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 1.4 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0 1.0 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 2.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 8.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 4.1 GO:0016758 transferase activity, transferring hexosyl groups(GO:0016758)
0.0 2.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 4.3 GO:0015631 tubulin binding(GO:0015631)
0.0 4.3 GO:0003779 actin binding(GO:0003779)
0.0 0.5 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.4 23.1 PID LKB1 PATHWAY LKB1 signaling events
0.3 4.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.2 6.1 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.2 16.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 7.0 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 4.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 3.0 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 24.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
1.3 10.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.6 22.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.4 14.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.4 7.9 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3 4.5 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.3 4.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.2 2.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 6.1 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 5.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 2.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 1.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 2.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 2.3 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.6 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.0 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors