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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Lhx2_Hoxc5

Z-value: 0.80

Motif logo

Transcription factors associated with Lhx2_Hoxc5

Gene Symbol Gene ID Gene Info
ENSRNOG00000010551 LIM homeobox 2
ENSRNOG00000016598 homeo box C5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxc5rn6_v1_chr7_+_144628120_1446281200.401.3e-13Click!
Lhx2rn6_v1_chr3_+_22640545_22640604-0.401.6e-13Click!

Activity profile of Lhx2_Hoxc5 motif

Sorted Z-values of Lhx2_Hoxc5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_101791337 27.70 ENSRNOT00000046937
solute carrier family 5 member 12
chr10_-_34242985 22.80 ENSRNOT00000046438
similar to novel protein
chr2_+_200793571 19.96 ENSRNOT00000091444
hydroxyacid oxidase 2
chr3_+_171213936 19.59 ENSRNOT00000031586
phosphoenolpyruvate carboxykinase 1
chr18_-_15089988 19.31 ENSRNOT00000074116
meprin A subunit beta
chr13_-_83457888 19.17 ENSRNOT00000076289
ENSRNOT00000004065
SFT2 domain containing 2
chr3_+_159368273 18.87 ENSRNOT00000041688
serum/glucocorticoid regulated kinase 2
chr1_-_189182306 18.77 ENSRNOT00000021249
glycoprotein 2
chrM_+_9870 18.40 ENSRNOT00000044582
mitochondrially encoded NADH 4L dehydrogenase
chr1_-_189181901 16.71 ENSRNOT00000092022
glycoprotein 2
chr6_-_7058314 16.63 ENSRNOT00000045996
3-hydroxyanthranilate 3,4-dioxygenase
chr5_+_6373583 16.62 ENSRNOT00000084749

chr6_+_8284878 16.55 ENSRNOT00000009581
solute carrier family 3 member 1
chr4_+_88694583 16.40 ENSRNOT00000009202
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr8_+_85059051 15.78 ENSRNOT00000033196
glutamate-cysteine ligase, catalytic subunit
chr2_+_60337667 15.78 ENSRNOT00000024035
alanine-glyoxylate aminotransferase 2
chr13_-_50514151 15.63 ENSRNOT00000003951
renin
chrM_+_10160 15.33 ENSRNOT00000042928
mitochondrially encoded NADH dehydrogenase 4
chr17_-_9762813 14.83 ENSRNOT00000033749
solute carrier family 34 member 1
chr4_+_61814974 14.77 ENSRNOT00000074951
aldo-keto reductase family 1 member B10
chr9_-_4876023 14.31 ENSRNOT00000065839
similar to Sulfotransferase K1 (rSULT1C2)
chr3_-_94808861 13.80 ENSRNOT00000038464
proline rich and Gla domain 4
chr13_-_67206688 13.28 ENSRNOT00000003630
ENSRNOT00000090693
phospholipase A2 group IVA
chr8_-_84320714 13.03 ENSRNOT00000079356
ENSRNOT00000088487
tubulointerstitial nephritis antigen
chr13_-_77821312 13.02 ENSRNOT00000082110

chr3_-_76518601 12.76 ENSRNOT00000071021
olfactory receptor 623
chr19_-_37796089 12.46 ENSRNOT00000024891
RAN binding protein 10
chr1_-_267463694 12.28 ENSRNOT00000084851
ENSRNOT00000016645
collagen type XVII alpha 1 chain
chr9_+_4107246 12.18 ENSRNOT00000078212

chr17_+_69761118 11.85 ENSRNOT00000023739
aldo-keto reductase family 1, member C3
chr2_+_256964860 11.76 ENSRNOT00000073547
interferon-induced protein 44-like
chr1_-_224698514 11.72 ENSRNOT00000024234
solute carrier family 22, member 25
chr2_-_216382244 11.62 ENSRNOT00000086695
ENSRNOT00000087259
pancreatic alpha-amylase-like
chr19_+_15081590 11.44 ENSRNOT00000024187
carboxylesterase 1F
chr3_+_159936856 11.31 ENSRNOT00000078703
hepatocyte nuclear factor 4, alpha
chr1_-_73399579 11.31 ENSRNOT00000077186
leukocyte immunoglobulin like receptor B4
chr2_-_216348194 11.24 ENSRNOT00000087839
pancreatic alpha-amylase-like
chr11_+_85263536 11.21 ENSRNOT00000046465

chr4_-_176381477 10.82 ENSRNOT00000048367
solute carrier organic anion transporter family, member 1a6
chrM_+_7919 10.81 ENSRNOT00000046108
mitochondrially encoded ATP synthase 6
chr1_+_32221636 10.78 ENSRNOT00000022346
ENSRNOT00000089941
solute carrier family 6 member 18
chr18_+_55466373 10.71 ENSRNOT00000074629
interferon-inducible GTPase 1-like
chrM_+_7006 10.50 ENSRNOT00000043693
mitochondrially encoded cytochrome c oxidase II
chr5_-_12172009 10.05 ENSRNOT00000061903
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr8_+_49713190 10.05 ENSRNOT00000022074
FXYD domain-containing ion transport regulator 2
chr9_+_95161157 10.01 ENSRNOT00000071200
UDP glucuronosyltransferase family 1 member A5
chr5_+_24410863 9.98 ENSRNOT00000010591
tumor protein p53 inducible nuclear protein 1
chr1_+_150310319 9.89 ENSRNOT00000042081
olfactory receptor 34
chr20_+_32717564 9.88 ENSRNOT00000030642
regulatory factor X, 6
chr9_+_8054466 9.88 ENSRNOT00000081513
adhesion G protein-coupled receptor E4
chr4_+_31229913 9.82 ENSRNOT00000077134
ENSRNOT00000087897
sterile alpha motif domain containing 9-like
chr4_+_148782479 9.81 ENSRNOT00000018133
similar to hypothetical protein MGC6835
chr14_-_6533524 9.78 ENSRNOT00000079795
ATP-binding cassette, subfamily G (WHITE), member 3-like 1
chrM_+_11736 9.77 ENSRNOT00000048767
mitochondrially encoded NADH dehydrogenase 5
chr13_+_89386023 9.74 ENSRNOT00000086223
Fc fragment of IgG receptor IIIa
chr1_+_48273611 9.72 ENSRNOT00000022254
ENSRNOT00000022068
solute carrier family 22 member 1
chr20_+_3176107 9.70 ENSRNOT00000001036
RT1 class Ib, locus S3
chr4_-_117607428 9.47 ENSRNOT00000021243
probable N-acetyltransferase CML6
chr10_-_82117109 9.40 ENSRNOT00000079711
ATP binding cassette subfamily C member 3
chr7_-_107768072 9.39 ENSRNOT00000093189
N-myc downstream regulated 1
chr3_-_14643897 9.37 ENSRNOT00000082008
ENSRNOT00000025983
glycoprotein, alpha-galactosyltransferase 1
chr4_+_88184956 9.37 ENSRNOT00000077129
vomeronasal 1 receptor 83
chr3_+_20303979 9.31 ENSRNOT00000058331

chr9_+_61692154 9.29 ENSRNOT00000082300
heat shock protein family E member 1
chr6_-_140880070 9.28 ENSRNOT00000073779
uncharacterized LOC691828
chr14_-_64476796 9.26 ENSRNOT00000029104
glucosidase, beta, acid 3
chrM_+_3904 9.20 ENSRNOT00000040993
mitochondrially encoded NADH dehydrogenase 2
chr7_+_71057911 9.16 ENSRNOT00000037218
retinol dehydrogenase 16 (all-trans)
chr3_-_154627257 8.91 ENSRNOT00000018328
transglutaminase 2
chr2_+_23289374 8.68 ENSRNOT00000090666
ENSRNOT00000032783
dimethylglycine dehydrogenase
chr4_-_71229575 8.59 ENSRNOT00000076650
TRPM8 channel-associated factor 2
chr10_+_69412017 8.54 ENSRNOT00000009448
C-C motif chemokine ligand 2
chr4_-_163463718 8.49 ENSRNOT00000085671
killer cell lectin like receptor C1
chr4_-_70628470 8.48 ENSRNOT00000029319
trypsin 5
chr20_-_9855443 8.40 ENSRNOT00000090275
ENSRNOT00000066266
trefoil factor 3
chr4_+_88328061 8.37 ENSRNOT00000084775
vomeronasal 1 receptor 87
chrX_+_37329779 8.34 ENSRNOT00000038352
ENSRNOT00000088802
pyruvate dehydrogenase (lipoamide) alpha 1
chr2_-_200513564 8.21 ENSRNOT00000056173
phosphoglycerate dehydrogenase
chr1_-_101095594 8.17 ENSRNOT00000027944
Fc fragment of IgG receptor and transporter
chr13_+_82369493 8.11 ENSRNOT00000003733
selectin L
chr2_+_60169517 8.06 ENSRNOT00000080974
prolactin receptor
chr10_-_90307658 8.05 ENSRNOT00000092102
solute carrier family 4 member 1
chrM_+_7758 7.92 ENSRNOT00000046201
mitochondrially encoded ATP synthase 8
chr4_+_157107469 7.81 ENSRNOT00000015678
complement C1r subcomponent like
chr10_+_95770154 7.80 ENSRNOT00000030300
helicase with zinc finger
chr3_-_14229067 7.80 ENSRNOT00000025534
ENSRNOT00000092865
complement C5
chr4_-_72074683 7.64 ENSRNOT00000071511
family with sequence similarity 115, member C
chr2_+_80269661 7.58 ENSRNOT00000015975

chr1_-_263803150 7.58 ENSRNOT00000017840
cytochrome P450, family 2, subfamily c, polypeptide 23
chr14_-_45859908 7.57 ENSRNOT00000086994
phosphoglucomutase 2
chr9_-_105693357 7.56 ENSRNOT00000066968
nudix hydrolase 12
chr20_+_3246739 7.50 ENSRNOT00000061299
RT1 class I, locus T24, gene 2
chr12_-_46493203 7.47 ENSRNOT00000057036
citron rho-interacting serine/threonine kinase
chr3_+_19690016 7.43 ENSRNOT00000085460

chr20_-_45053640 7.43 ENSRNOT00000072256
similar to Na+ dependent glucose transporter 1
chrM_+_8599 7.40 ENSRNOT00000049683
mitochondrially encoded cytochrome C oxidase III
chr19_+_15081158 7.37 ENSRNOT00000074070
carboxylesterase 1F
chr8_+_85489553 7.33 ENSRNOT00000082158
ribosomal protein L12, pseudogene 1
chr15_+_42808897 7.30 ENSRNOT00000023475
cholinergic receptor nicotinic alpha 2 subunit
chrX_-_15347591 7.29 ENSRNOT00000037066
translocase of inner mitochondrial membrane 17b
chr2_+_248398917 7.29 ENSRNOT00000045855
guanylate binding protein 1
chr1_+_140998240 7.20 ENSRNOT00000023506
ENSRNOT00000090897
abhydrolase domain containing 2
chr3_+_16753703 7.11 ENSRNOT00000077741

chr8_+_2604962 7.01 ENSRNOT00000009993
caspase 1
chr20_-_14020007 6.91 ENSRNOT00000093521
gamma-glutamyltransferase 1
chr3_+_72134731 6.88 ENSRNOT00000083592
yippee-like 4
chr2_+_187447501 6.78 ENSRNOT00000038589
IQ motif containing GTPase activating protein 3
chr1_+_229519506 6.76 ENSRNOT00000016593
glycine-N-acyltransferase-like 2
chr1_-_116153722 6.72 ENSRNOT00000041605
formyl peptide receptor 3
chr6_-_143195445 6.61 ENSRNOT00000078672

chr4_-_163762434 6.45 ENSRNOT00000081854
immunoreceptor Ly49si1
chr2_+_220432037 6.45 ENSRNOT00000021988
ferric-chelate reductase 1
chr7_-_15073052 6.43 ENSRNOT00000037708
zinc finger protein 799
chr4_-_165026414 6.41 ENSRNOT00000071421
killer cell lectin-like receptor, subfamily A, member 1
chr4_-_64981384 6.38 ENSRNOT00000017338
cAMP responsive element binding protein 3-like 2
chr3_+_17889972 6.36 ENSRNOT00000073021

chr14_+_5928737 6.32 ENSRNOT00000071877
ENSRNOT00000040985
ENSRNOT00000074889
macrophage activation 2 like
chr10_-_57837602 6.31 ENSRNOT00000075185
NLR family, pyrin domain containing 1B
chr9_+_71915421 6.29 ENSRNOT00000020447
phosphoinositide kinase, FYVE-type zinc finger containing
chr9_+_95202632 6.27 ENSRNOT00000025652
UDP glucuronosyltransferase family 1 member A5
chr6_-_122239614 6.24 ENSRNOT00000005015
galactosylceramidase
chr7_+_18068060 6.23 ENSRNOT00000065474
vomeronasal 1 receptor 107
chr7_-_3707226 6.23 ENSRNOT00000064380
olfactory receptor 879
chr6_-_111417813 6.21 ENSRNOT00000016324
ENSRNOT00000085458
serine palmitoyltransferase, long chain base subunit 2
chr2_+_251983339 6.06 ENSRNOT00000020230
mucolipin 3
chr18_-_41389510 6.02 ENSRNOT00000005476
ENSRNOT00000005446
semaphorin 6A
chr1_+_141767940 6.01 ENSRNOT00000064034
zinc finger protein 710
chr2_+_186776644 6.00 ENSRNOT00000046778
Fc receptor-like 3
chr2_-_33025271 5.99 ENSRNOT00000074941
microtubule associated serine/threonine kinase family member 4
chr4_-_88684415 5.98 ENSRNOT00000009001
similar to 40S ribosomal protein S7 (S8)
chr1_-_38538987 5.96 ENSRNOT00000090406
ENSRNOT00000071275
zinc finger protein 728-like
chr13_-_78885464 5.95 ENSRNOT00000003828
aspartyl-tRNA synthetase 2 (mitochondrial)
chr14_-_38128015 5.95 ENSRNOT00000090303
ENSRNOT00000034642
NIPA-like domain containing 1
chr5_-_147412705 5.94 ENSRNOT00000010688
similar to mKIAA1522 protein
chr7_+_29435444 5.92 ENSRNOT00000008613
solute carrier family 5 member 8
chr5_+_58995249 5.91 ENSRNOT00000023411
coiled-coil domain containing 107
chr8_+_128027958 5.90 ENSRNOT00000045049
acetyl-Coenzyme A acyltransferase 1B
chr1_+_213686046 5.89 ENSRNOT00000019808
NACHT, LRR and PYD domains-containing protein 6-like
chr2_-_192288568 5.81 ENSRNOT00000067346

chr20_+_13817795 5.81 ENSRNOT00000036518
glutathione S-transferase, theta 3
chr4_-_164453171 5.79 ENSRNOT00000077539
ENSRNOT00000083610
ENSRNOT00000079975
Ly49 stimulatory receptor 6
chr7_-_71139267 5.79 ENSRNOT00000065232
similar to Retinol dehydrogenase type II (RODH II) (29 k-protein)
chr1_-_166939541 5.74 ENSRNOT00000079675
folate receptor 1
chr16_-_29936307 5.73 ENSRNOT00000088707
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr1_-_263762785 5.71 ENSRNOT00000018221
carboxypeptidase N subunit 1
chr1_+_213676954 5.70 ENSRNOT00000050551
NLR family, pyrin domain containing 6
chr4_+_163174487 5.69 ENSRNOT00000088108
C-type lectin domain family 9, member A
chr2_-_147392062 5.68 ENSRNOT00000021535
transmembrane 4 L six family member 1
chr1_-_224533219 5.62 ENSRNOT00000051289
integral membrane transport protein UST5r
chr14_-_84662143 5.61 ENSRNOT00000057529
ENSRNOT00000080078
HORMA domain containing 2
chr6_+_139405966 5.60 ENSRNOT00000088974

chr12_-_24775891 5.58 ENSRNOT00000074851
Williams Beuren syndrome chromosome region 27
chr3_+_119561290 5.56 ENSRNOT00000015843
biliverdin reductase A
chr2_+_30685840 5.56 ENSRNOT00000031385
coiled-coil domain containing 125
chr4_+_1591444 5.53 ENSRNOT00000078277
olfactory receptor 1245
chr15_-_93765498 5.51 ENSRNOT00000093297
MYC binding protein 2, E3 ubiquitin protein ligase
chr17_-_43504604 5.48 ENSRNOT00000083829
ENSRNOT00000066313
solute carrier family 17 member 1
chr7_-_142318620 5.46 ENSRNOT00000006351
chymotrypsin-like elastase family, member 1
chr1_+_61786900 5.42 ENSRNOT00000090287

chrM_+_9451 5.39 ENSRNOT00000041241
mitochondrially encoded NADH dehydrogenase 3
chr17_-_43807540 5.36 ENSRNOT00000074763
similar to CG31613-PA
chrM_-_14061 5.35 ENSRNOT00000051268
mitochondrially encoded NADH dehydrogenase 6
chr4_+_166993669 5.30 ENSRNOT00000045376
taste receptor, type 2, member 109
chr10_+_84966989 5.27 ENSRNOT00000013580
secernin 2
chr20_+_44680449 5.26 ENSRNOT00000000728
Traf3 interacting protein 2
chr16_-_37177033 5.26 ENSRNOT00000014015
F-box protein 8
chr4_+_88207124 5.25 ENSRNOT00000082459
vomeronasal 1 receptor 84
chr4_+_99823252 5.25 ENSRNOT00000013587
RNA polymerase I subunit A
chr17_-_79085076 5.24 ENSRNOT00000057851
family with sequence similarity 171, member A1
chr10_-_34961349 5.24 ENSRNOT00000004885
heterogeneous nuclear ribonucleoprotein A/B
chr1_-_256734719 5.23 ENSRNOT00000021546
ENSRNOT00000089456
myoferlin
chr11_+_54619129 5.21 ENSRNOT00000059924
T cell receptor associated transmembrane adaptor 1
chr13_-_80775230 5.17 ENSRNOT00000091389
ENSRNOT00000004762
flavin containing monooxygenase 2
chr19_-_601469 5.17 ENSRNOT00000016462
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr3_+_20163337 5.16 ENSRNOT00000075136

chr3_+_11763706 5.14 ENSRNOT00000078366
SH2 domain containing 3C
chrX_+_112311251 5.13 ENSRNOT00000086698

chr4_-_164406146 5.12 ENSRNOT00000090110
killer cell lectin-like receptor subfamily A, member 22
chr11_+_85430400 5.11 ENSRNOT00000083198

chr13_-_91981432 5.10 ENSRNOT00000004637

chr1_-_252808380 5.09 ENSRNOT00000025856
cholesterol 25-hydroxylase
chr10_-_89130339 5.08 ENSRNOT00000027640
enhancer of zeste 1 polycomb repressive complex 2 subunit
chr7_-_5818625 5.07 ENSRNOT00000051699
olfactory receptor 886
chr12_+_24761210 5.04 ENSRNOT00000002003
claudin 4
chr9_+_10013854 5.02 ENSRNOT00000077653
ENSRNOT00000072033
KH-type splicing regulatory protein
chr1_+_227240383 4.99 ENSRNOT00000074127
membrane spanning 4-domains A6E
chr6_+_86785771 4.99 ENSRNOT00000066702
pre-mRNA processing factor 39
chr20_+_3155652 4.97 ENSRNOT00000042882
RT1 class Ib, locus S2
chr11_+_31539016 4.96 ENSRNOT00000072856
interferon alpha and beta receptor subunit 2
chr3_+_19174027 4.96 ENSRNOT00000074445

chr8_+_69127708 4.95 ENSRNOT00000013490
small nuclear RNA activating complex, polypeptide 5
chr8_+_117117430 4.94 ENSRNOT00000073247
glutathione peroxidase 1
chr7_-_142180997 4.93 ENSRNOT00000087632
transcription factor CP2
chr4_-_165192647 4.92 ENSRNOT00000086461
killer cell lectin-like receptor, subfamily A, member 5
chr1_+_60117804 4.90 ENSRNOT00000080437
vomeronasal 1 receptor 8
chr9_+_95295701 4.89 ENSRNOT00000025045
UDP glucuronosyltransferase family 1 member A5
chr10_-_34961608 4.88 ENSRNOT00000033056
heterogeneous nuclear ribonucleoprotein A/B
chr19_+_53044379 4.86 ENSRNOT00000072369
forkhead box C2
chr1_-_101819478 4.85 ENSRNOT00000056181
glutamate-rich WD repeat containing 1
chr15_-_82581916 4.81 ENSRNOT00000057891
similar to ribosomal protein L27

Network of associatons between targets according to the STRING database.

First level regulatory network of Lhx2_Hoxc5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
8.9 26.6 GO:0016487 sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488)
8.9 35.5 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
6.7 20.0 GO:0018924 mandelate metabolic process(GO:0018924)
5.3 15.8 GO:0019265 glycine biosynthetic process, by transamination of glyoxylate(GO:0019265)
4.9 14.8 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
4.9 19.6 GO:0006114 glycerol biosynthetic process(GO:0006114)
4.6 4.6 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
4.2 16.6 GO:0019805 quinolinate biosynthetic process(GO:0019805)
3.9 15.8 GO:0097069 cellular response to thyroxine stimulus(GO:0097069)
3.6 18.2 GO:0002003 angiotensin maturation(GO:0002003)
3.4 16.9 GO:0006564 L-serine biosynthetic process(GO:0006564)
3.3 10.0 GO:0036446 myofibroblast differentiation(GO:0036446) response to methyl methanesulfonate(GO:0072702) cellular response to methyl methanesulfonate(GO:0072703) regulation of myofibroblast differentiation(GO:1904760)
3.2 9.7 GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
3.2 9.6 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
3.1 9.4 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
3.0 8.9 GO:0018199 peptidyl-glutamine modification(GO:0018199)
2.9 8.7 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
2.8 8.5 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
2.8 11.3 GO:1902569 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
2.8 25.1 GO:0052697 xenobiotic glucuronidation(GO:0052697)
2.6 28.5 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
2.5 7.6 GO:0019677 NADP catabolic process(GO:0006742) NAD catabolic process(GO:0019677)
2.4 9.4 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
2.1 6.2 GO:0006667 sphinganine metabolic process(GO:0006667)
1.9 5.7 GO:0060974 cell migration involved in heart formation(GO:0060974)
1.9 5.7 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
1.9 13.3 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
1.9 5.7 GO:0010133 proline catabolic process to glutamate(GO:0010133)
1.8 20.1 GO:0015747 urate transport(GO:0015747)
1.8 5.3 GO:0090024 negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024)
1.8 7.0 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
1.8 7.0 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
1.7 6.9 GO:0031179 peptide modification(GO:0031179)
1.6 4.9 GO:0009609 response to symbiotic bacterium(GO:0009609)
1.6 3.3 GO:0009608 response to symbiont(GO:0009608)
1.6 8.0 GO:0010037 response to carbon dioxide(GO:0010037)
1.6 9.4 GO:0042908 xenobiotic transport(GO:0042908)
1.5 4.5 GO:1901227 negative regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901227)
1.5 6.0 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
1.4 13.0 GO:0070543 response to linoleic acid(GO:0070543)
1.4 2.9 GO:2000464 positive regulation of astrocyte chemotaxis(GO:2000464)
1.4 10.1 GO:0019374 galactolipid metabolic process(GO:0019374)
1.4 8.6 GO:0010360 negative regulation of anion channel activity(GO:0010360)
1.4 4.2 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
1.4 2.8 GO:1904580 regulation of intracellular mRNA localization(GO:1904580)
1.4 15.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
1.4 4.1 GO:0071350 interleukin-12-mediated signaling pathway(GO:0035722) interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-12(GO:0071349) cellular response to interleukin-15(GO:0071350) regulation of monocyte extravasation(GO:2000437)
1.4 4.1 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
1.3 5.2 GO:0072592 oxygen metabolic process(GO:0072592)
1.2 7.3 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
1.2 3.6 GO:0045210 negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210)
1.2 17.9 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
1.2 4.7 GO:0098705 copper ion import across plasma membrane(GO:0098705) copper ion import into cell(GO:1902861)
1.2 8.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
1.2 3.5 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
1.2 2.3 GO:0009644 response to high light intensity(GO:0009644)
1.1 12.6 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
1.1 9.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
1.1 5.7 GO:0030070 insulin processing(GO:0030070)
1.1 3.4 GO:1903936 cellular response to sodium arsenite(GO:1903936)
1.1 4.5 GO:0048252 lauric acid metabolic process(GO:0048252)
1.1 5.6 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
1.1 3.3 GO:1900673 olefin metabolic process(GO:1900673)
1.1 5.5 GO:0061113 pancreas morphogenesis(GO:0061113)
1.1 3.3 GO:0071461 cellular response to redox state(GO:0071461)
1.1 10.6 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
1.0 2.1 GO:0097214 regulation of lysosomal membrane permeability(GO:0097213) positive regulation of lysosomal membrane permeability(GO:0097214)
1.0 23.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
1.0 5.2 GO:0009758 carbohydrate utilization(GO:0009758)
1.0 3.1 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
1.0 3.1 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
1.0 3.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
1.0 3.1 GO:2000422 regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
1.0 6.0 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
1.0 8.0 GO:0090241 negative regulation of histone H4 acetylation(GO:0090241)
1.0 9.9 GO:0003310 pancreatic A cell differentiation(GO:0003310)
1.0 4.0 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
1.0 3.9 GO:0045658 regulation of neutrophil differentiation(GO:0045658)
1.0 2.9 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
1.0 9.6 GO:0015697 quaternary ammonium group transport(GO:0015697)
1.0 41.1 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
1.0 43.0 GO:0035456 response to interferon-beta(GO:0035456)
0.9 10.3 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.9 3.8 GO:0006172 ADP biosynthetic process(GO:0006172)
0.9 1.8 GO:0016095 polyprenol catabolic process(GO:0016095)
0.9 2.7 GO:0071245 cellular response to carbon monoxide(GO:0071245)
0.9 3.5 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.9 4.4 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.9 4.4 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.9 2.6 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.9 4.3 GO:0031055 chromatin remodeling at centromere(GO:0031055) pericentric heterochromatin assembly(GO:0031508)
0.9 2.6 GO:0036395 pancreatic amylase secretion(GO:0036395) regulation of pancreatic amylase secretion(GO:1902276) positive regulation of histamine secretion by mast cell(GO:1903595)
0.9 1.7 GO:0000958 mitochondrial mRNA catabolic process(GO:0000958) positive regulation of mitochondrial RNA catabolic process(GO:0000962)
0.8 0.8 GO:0007493 endodermal cell fate determination(GO:0007493)
0.8 3.3 GO:0071492 cellular response to UV-A(GO:0071492)
0.8 8.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.8 4.8 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.8 3.2 GO:0035772 interleukin-13-mediated signaling pathway(GO:0035772)
0.8 2.4 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.8 2.4 GO:0034031 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
0.8 9.9 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.8 5.3 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.7 20.2 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.7 2.2 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.7 2.9 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.7 2.2 GO:0051933 lactate biosynthetic process(GO:0019249) amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.7 1.5 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.7 2.2 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.7 2.2 GO:0070814 hydrogen sulfide biosynthetic process(GO:0070814)
0.7 5.0 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.7 2.9 GO:0070269 pyroptosis(GO:0070269)
0.7 4.3 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.7 3.6 GO:0001555 oocyte growth(GO:0001555)
0.7 4.9 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.7 2.1 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.7 2.8 GO:1990375 baculum development(GO:1990375)
0.7 2.1 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.7 3.5 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.7 2.1 GO:0072697 protein localization to cell cortex(GO:0072697)
0.7 2.7 GO:0070827 chromatin maintenance(GO:0070827)
0.7 3.4 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.7 4.7 GO:0015670 carbon dioxide transport(GO:0015670)
0.7 2.0 GO:0000105 histidine biosynthetic process(GO:0000105)
0.7 9.3 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.7 2.0 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.7 5.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.6 3.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.6 2.6 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.6 12.2 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.6 4.4 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.6 3.1 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.6 2.5 GO:2000814 positive regulation of barbed-end actin filament capping(GO:2000814)
0.6 1.8 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.6 1.8 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.6 3.5 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.6 2.9 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.6 9.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.6 2.9 GO:0034227 tRNA thio-modification(GO:0034227)
0.6 2.3 GO:0032701 negative regulation of interleukin-18 production(GO:0032701)
0.6 5.1 GO:0035754 B cell chemotaxis(GO:0035754)
0.6 6.8 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.6 2.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.6 5.6 GO:0045144 meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177)
0.6 10.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.6 2.8 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.6 4.4 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.5 4.4 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.5 2.7 GO:0098953 gamma-aminobutyric acid receptor clustering(GO:0097112) receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.5 2.1 GO:0006272 leading strand elongation(GO:0006272)
0.5 1.6 GO:0052572 response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.5 1.6 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.5 1.6 GO:0006431 methionyl-tRNA aminoacylation(GO:0006431)
0.5 6.2 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.5 1.5 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.5 3.0 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.5 4.6 GO:0070995 NADPH oxidation(GO:0070995)
0.5 1.5 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.5 4.0 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.5 4.9 GO:0009642 response to light intensity(GO:0009642)
0.5 1.0 GO:0072347 response to anesthetic(GO:0072347)
0.5 6.3 GO:0050718 positive regulation of interleukin-1 secretion(GO:0050716) positive regulation of interleukin-1 beta secretion(GO:0050718)
0.5 1.9 GO:0051106 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.5 1.4 GO:0006552 leucine catabolic process(GO:0006552)
0.5 1.4 GO:0070295 renal water absorption(GO:0070295)
0.5 4.3 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.5 19.5 GO:0050912 detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.5 1.4 GO:1904835 vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835)
0.5 2.4 GO:0060327 cytoplasmic actin-based contraction involved in cell motility(GO:0060327)
0.5 2.3 GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.5 3.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.5 4.1 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.5 3.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.5 5.5 GO:0070255 regulation of mucus secretion(GO:0070255)
0.5 3.6 GO:0022614 membrane to membrane docking(GO:0022614)
0.4 2.7 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.4 3.1 GO:0042940 D-amino acid transport(GO:0042940)
0.4 3.5 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.4 2.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.4 1.3 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.4 1.3 GO:0002644 negative regulation of tolerance induction(GO:0002644)
0.4 1.7 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.4 1.3 GO:0044375 regulation of peroxisome size(GO:0044375)
0.4 3.9 GO:0008063 Toll signaling pathway(GO:0008063)
0.4 1.7 GO:1904923 regulation of mitophagy in response to mitochondrial depolarization(GO:1904923)
0.4 3.0 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.4 6.8 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.4 5.5 GO:0046415 urate metabolic process(GO:0046415)
0.4 4.5 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.4 4.1 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.4 5.3 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.4 2.4 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.4 3.2 GO:0046884 follicle-stimulating hormone secretion(GO:0046884)
0.4 1.2 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.4 2.8 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.4 10.8 GO:0042168 heme metabolic process(GO:0042168)
0.4 4.0 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.4 3.6 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.4 5.5 GO:0032060 bleb assembly(GO:0032060)
0.4 2.3 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.4 1.5 GO:0002084 protein depalmitoylation(GO:0002084)
0.4 1.1 GO:0048382 lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378) mesendoderm development(GO:0048382) regulation of cardiac ventricle development(GO:1904412)
0.4 4.5 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.4 1.9 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.4 1.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.4 1.5 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.4 1.1 GO:0035973 aggrephagy(GO:0035973)
0.4 1.1 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.4 1.1 GO:0009597 detection of virus(GO:0009597)
0.4 9.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.4 1.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.4 1.4 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.4 3.2 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.4 2.1 GO:1903142 negative regulation of excitatory postsynaptic potential(GO:0090394) positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.3 6.5 GO:0006855 drug transmembrane transport(GO:0006855)
0.3 2.7 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.3 5.5 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.3 4.1 GO:0006265 DNA topological change(GO:0006265)
0.3 0.7 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.3 0.7 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.3 1.0 GO:0003162 atrioventricular node development(GO:0003162)
0.3 2.0 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.3 0.3 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.3 1.0 GO:0015680 intracellular copper ion transport(GO:0015680)
0.3 6.3 GO:0032288 myelin assembly(GO:0032288)
0.3 0.7 GO:0034421 post-translational protein acetylation(GO:0034421)
0.3 2.0 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.3 1.3 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.3 3.3 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.3 1.3 GO:0070314 G1 to G0 transition(GO:0070314)
0.3 1.9 GO:0036438 maintenance of lens transparency(GO:0036438)
0.3 12.1 GO:1901998 toxin transport(GO:1901998)
0.3 8.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.3 0.9 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168)
0.3 0.9 GO:0060383 positive regulation of DNA strand elongation(GO:0060383)
0.3 2.2 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.3 0.6 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.3 3.9 GO:0034063 stress granule assembly(GO:0034063)
0.3 0.9 GO:2000017 endocardial cushion cell differentiation(GO:0061443) positive regulation of determination of dorsal identity(GO:2000017)
0.3 9.5 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.3 2.9 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.3 2.9 GO:0097264 self proteolysis(GO:0097264)
0.3 5.2 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.3 1.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.3 2.0 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.3 1.7 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.3 3.4 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.3 1.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.3 1.4 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.3 1.1 GO:0030449 regulation of complement activation(GO:0030449)
0.3 1.4 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.3 1.6 GO:0006776 vitamin A metabolic process(GO:0006776)
0.3 2.7 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.3 1.8 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.3 1.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.3 3.2 GO:0071168 protein localization to chromatin(GO:0071168)
0.3 1.6 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945) cellular response to leucine(GO:0071233)
0.3 2.9 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.3 2.6 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.3 1.0 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.3 4.4 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.3 1.0 GO:1903413 cellular response to bile acid(GO:1903413)
0.3 6.9 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.3 2.0 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.2 1.5 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.2 1.2 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.2 2.2 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.2 3.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.2 5.7 GO:0048240 sperm capacitation(GO:0048240)
0.2 2.3 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.2 2.3 GO:0006968 cellular defense response(GO:0006968)
0.2 0.9 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.2 0.7 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.2 0.9 GO:0035747 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.2 1.6 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.2 0.7 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.2 2.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.2 1.8 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.2 4.0 GO:0042119 neutrophil activation(GO:0042119)
0.2 4.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 5.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.2 2.0 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.2 2.2 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.2 3.2 GO:0045986 negative regulation of smooth muscle contraction(GO:0045986)
0.2 0.6 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.2 0.9 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.2 1.9 GO:0009235 cobalamin metabolic process(GO:0009235)
0.2 1.7 GO:0019388 galactose catabolic process(GO:0019388)
0.2 2.5 GO:0051382 kinetochore assembly(GO:0051382)
0.2 2.3 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.2 6.5 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.2 1.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.2 0.8 GO:0060594 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776) mammary gland specification(GO:0060594)
0.2 5.7 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.2 6.3 GO:0006972 hyperosmotic response(GO:0006972)
0.2 3.2 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.2 1.0 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.2 4.6 GO:0006730 one-carbon metabolic process(GO:0006730)
0.2 5.8 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.2 2.9 GO:0042438 melanin biosynthetic process(GO:0042438)
0.2 2.8 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.2 0.6 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.2 0.4 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.2 3.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 1.6 GO:0018344 protein geranylgeranylation(GO:0018344)
0.2 0.5 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.2 1.6 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.2 2.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.2 2.6 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.2 0.3 GO:1901143 insulin catabolic process(GO:1901143)
0.2 0.9 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.2 0.3 GO:0048539 bone marrow development(GO:0048539)
0.2 2.9 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.2 1.0 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.2 4.4 GO:0009303 rRNA transcription(GO:0009303)
0.2 3.9 GO:1904894 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.2 0.5 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.2 4.0 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.2 7.2 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968) cellular response to unfolded protein(GO:0034620)
0.2 1.2 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.2 2.8 GO:0031268 pseudopodium organization(GO:0031268)
0.2 2.5 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.2 1.0 GO:0002446 neutrophil mediated immunity(GO:0002446)
0.2 3.1 GO:0007567 parturition(GO:0007567)
0.2 10.7 GO:0006334 nucleosome assembly(GO:0006334)
0.2 3.4 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.2 1.1 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.2 0.8 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.2 9.7 GO:0030101 natural killer cell activation(GO:0030101)
0.2 2.7 GO:0002820 negative regulation of adaptive immune response(GO:0002820)
0.2 0.5 GO:0021997 neural plate axis specification(GO:0021997)
0.2 5.1 GO:0002548 monocyte chemotaxis(GO:0002548)
0.2 0.5 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.2 2.9 GO:0002360 T cell lineage commitment(GO:0002360)
0.2 1.5 GO:0002517 T cell tolerance induction(GO:0002517)
0.2 1.4 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950) induction of positive chemotaxis(GO:0050930)
0.2 4.4 GO:0006801 superoxide metabolic process(GO:0006801)
0.1 5.5 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 0.7 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.1 0.7 GO:1904400 response to Thyroid stimulating hormone(GO:1904400) cellular response to Thyroid stimulating hormone(GO:1904401)
0.1 2.9 GO:0070228 regulation of lymphocyte apoptotic process(GO:0070228)
0.1 1.2 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 199.2 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.1 0.7 GO:0003360 brainstem development(GO:0003360)
0.1 7.6 GO:0033574 response to testosterone(GO:0033574)
0.1 3.6 GO:0006829 zinc II ion transport(GO:0006829)
0.1 0.4 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.8 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 1.4 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 4.0 GO:0010288 response to lead ion(GO:0010288)
0.1 1.1 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.1 1.4 GO:0007097 nuclear migration(GO:0007097)
0.1 5.7 GO:0050715 positive regulation of cytokine secretion(GO:0050715)
0.1 3.2 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 1.3 GO:0032674 regulation of interleukin-5 production(GO:0032674)
0.1 0.6 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 9.9 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.1 1.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 1.0 GO:0045954 positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.1 1.6 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 0.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.1 1.1 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 2.0 GO:0030574 collagen catabolic process(GO:0030574)
0.1 0.6 GO:1902022 lysine transport(GO:0015819) L-lysine transport(GO:1902022) L-lysine transmembrane transport(GO:1903401)
0.1 0.4 GO:0060857 establishment of glial blood-brain barrier(GO:0060857)
0.1 0.3 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.1 1.8 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.1 0.7 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 1.1 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.1 1.4 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 4.7 GO:0042220 response to cocaine(GO:0042220)
0.1 0.5 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 4.0 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.1 0.4 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 0.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 1.1 GO:0051205 protein insertion into membrane(GO:0051205)
0.1 0.6 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 3.2 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 0.2 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.1 4.4 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.1 0.5 GO:0061709 reticulophagy(GO:0061709)
0.1 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 4.2 GO:0006278 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.1 1.9 GO:0019835 cytolysis(GO:0019835)
0.1 0.9 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.6 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.6 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.2 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
0.1 0.6 GO:0046512 sphingosine biosynthetic process(GO:0046512)
0.1 1.9 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.1 0.2 GO:0043201 response to leucine(GO:0043201)
0.1 0.6 GO:0045059 positive regulation of T cell differentiation in thymus(GO:0033089) positive thymic T cell selection(GO:0045059) positive regulation of thymocyte aggregation(GO:2000400)
0.1 1.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 1.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.6 GO:0051182 coenzyme transport(GO:0051182)
0.1 1.7 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.1 0.5 GO:0016926 protein desumoylation(GO:0016926)
0.1 2.5 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.1 1.0 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 1.3 GO:0030318 melanocyte differentiation(GO:0030318)
0.1 0.4 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1 0.2 GO:0014908 myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.1 1.2 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.1 0.9 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 5.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 0.7 GO:0060539 diaphragm development(GO:0060539)
0.1 2.2 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.1 0.3 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.1 2.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.6 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 1.0 GO:0045332 phospholipid translocation(GO:0045332)
0.1 5.2 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.1 1.5 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.1 0.8 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.1 1.1 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.9 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 6.7 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.1 1.2 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.1 0.6 GO:0000338 protein deneddylation(GO:0000338)
0.1 2.3 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 1.4 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.1 0.2 GO:2000618 regulation of histone H4-K16 acetylation(GO:2000618)
0.1 1.5 GO:0034605 cellular response to heat(GO:0034605)
0.1 1.9 GO:0097202 activation of cysteine-type endopeptidase activity(GO:0097202)
0.1 1.2 GO:0000266 mitochondrial fission(GO:0000266)
0.1 6.6 GO:0042742 defense response to bacterium(GO:0042742)
0.1 1.2 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 0.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.1 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
0.1 0.4 GO:0033504 floor plate development(GO:0033504)
0.1 0.5 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 0.8 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 0.3 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 1.1 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.8 GO:0010458 exit from mitosis(GO:0010458)
0.0 1.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.8 GO:0097502 mannosylation(GO:0097502)
0.0 1.2 GO:0001885 endothelial cell development(GO:0001885)
0.0 2.1 GO:0007569 cell aging(GO:0007569)
0.0 10.4 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.1 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 2.7 GO:0060996 dendritic spine development(GO:0060996)
0.0 0.2 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 1.3 GO:0033619 membrane protein proteolysis(GO:0033619)
0.0 1.5 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.6 GO:0046037 GMP metabolic process(GO:0046037)
0.0 3.9 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.0 0.6 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.5 GO:1900003 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.8 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 1.3 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.2 GO:0031497 chromatin assembly(GO:0031497)
0.0 0.1 GO:0070202 regulation of establishment of protein localization to chromosome(GO:0070202)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 13.6 GO:0006955 immune response(GO:0006955)
0.0 0.5 GO:0001556 oocyte maturation(GO:0001556)
0.0 1.2 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.2 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.5 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.4 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.6 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 1.8 GO:0021987 cerebral cortex development(GO:0021987)
0.0 0.4 GO:0031572 mitotic G2 DNA damage checkpoint(GO:0007095) G2 DNA damage checkpoint(GO:0031572)
0.0 0.5 GO:0000154 rRNA modification(GO:0000154)
0.0 0.3 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 0.2 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.8 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 7.4 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 2.1 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.3 GO:0048662 negative regulation of smooth muscle cell proliferation(GO:0048662)
0.0 0.3 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.1 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910)
0.0 0.0 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.0 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.0 0.1 GO:0030497 fatty acid elongation(GO:0030497)
0.0 1.0 GO:0006364 rRNA processing(GO:0006364)
0.0 0.3 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.5 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.3 GO:0033045 regulation of sister chromatid segregation(GO:0033045)
0.0 0.4 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.7 GO:0032398 MHC class Ib protein complex(GO:0032398)
3.2 3.2 GO:0000798 nuclear cohesin complex(GO:0000798)
2.8 8.3 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
2.1 8.5 GO:0044299 C-fiber(GO:0044299)
2.0 9.9 GO:0072557 IPAF inflammasome complex(GO:0072557)
1.8 7.3 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
1.6 11.3 GO:0005579 membrane attack complex(GO:0005579)
1.6 6.3 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
1.4 5.7 GO:0061702 inflammasome complex(GO:0061702)
1.4 4.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
1.2 18.4 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
1.1 3.4 GO:1990826 nucleoplasmic periphery of the nuclear pore complex(GO:1990826)
1.1 3.4 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
1.1 56.1 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
1.1 3.2 GO:0070826 paraferritin complex(GO:0070826)
1.0 7.2 GO:0097524 sperm plasma membrane(GO:0097524)
1.0 8.0 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
1.0 4.9 GO:0097413 Lewy body(GO:0097413)
0.9 2.8 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.9 3.6 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.9 3.6 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.9 4.4 GO:0071953 elastic fiber(GO:0071953)
0.9 2.6 GO:0035577 azurophil granule membrane(GO:0035577)
0.9 6.8 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.8 6.2 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.8 0.8 GO:0000815 ESCRT III complex(GO:0000815)
0.8 2.3 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.7 2.2 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.7 3.7 GO:0000243 commitment complex(GO:0000243)
0.7 14.5 GO:0019013 viral nucleocapsid(GO:0019013)
0.7 3.5 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.7 10.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.7 2.1 GO:1990836 lysosomal matrix(GO:1990836)
0.7 3.4 GO:0070552 BRISC complex(GO:0070552)
0.7 6.8 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.7 3.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.7 1.3 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.7 3.3 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.6 1.9 GO:0045025 mitochondrial degradosome(GO:0045025)
0.6 1.9 GO:0019815 B cell receptor complex(GO:0019815)
0.6 53.7 GO:0031526 brush border membrane(GO:0031526)
0.6 1.9 GO:0045203 intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203)
0.6 1.8 GO:1990032 parallel fiber(GO:1990032)
0.6 17.3 GO:0042588 zymogen granule(GO:0042588)
0.6 2.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.6 3.5 GO:0070820 tertiary granule(GO:0070820)
0.6 7.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.6 9.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.5 4.3 GO:0001740 Barr body(GO:0001740)
0.5 2.1 GO:0061474 phagolysosome(GO:0032010) phagolysosome membrane(GO:0061474)
0.5 10.7 GO:0030056 hemidesmosome(GO:0030056)
0.5 8.1 GO:0042101 T cell receptor complex(GO:0042101)
0.5 1.5 GO:0044317 rod spherule(GO:0044317)
0.5 4.7 GO:0032437 cuticular plate(GO:0032437)
0.5 9.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.5 2.7 GO:0098871 postsynaptic actin cytoskeleton(GO:0098871) postsynaptic cytoskeleton(GO:0099571)
0.5 0.9 GO:0005608 laminin-3 complex(GO:0005608)
0.4 3.1 GO:0030870 Mre11 complex(GO:0030870)
0.4 5.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.4 1.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.4 1.6 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.4 1.6 GO:0097196 Shu complex(GO:0097196)
0.4 4.0 GO:0043020 NADPH oxidase complex(GO:0043020)
0.4 4.2 GO:0044754 autolysosome(GO:0044754)
0.4 1.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.4 2.3 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.4 2.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.4 1.8 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.4 2.2 GO:0035189 Rb-E2F complex(GO:0035189)
0.3 1.4 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.3 1.4 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.3 1.4 GO:0042585 germinal vesicle(GO:0042585) dendritic branch(GO:0044307)
0.3 26.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.3 8.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.3 50.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.3 1.8 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.3 2.4 GO:0097443 sorting endosome(GO:0097443)
0.3 4.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.3 1.8 GO:0005726 perichromatin fibrils(GO:0005726)
0.3 8.2 GO:0070469 respiratory chain(GO:0070469)
0.3 7.0 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.3 3.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.3 2.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.3 2.8 GO:0001939 female pronucleus(GO:0001939)
0.3 1.0 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.3 1.5 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.3 5.0 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 2.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.2 9.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 2.8 GO:0031143 pseudopodium(GO:0031143)
0.2 23.9 GO:0031225 anchored component of membrane(GO:0031225)
0.2 0.7 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.2 1.1 GO:0034455 t-UTP complex(GO:0034455)
0.2 1.8 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.2 3.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.2 1.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.2 3.0 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 1.5 GO:0030991 intraciliary transport particle A(GO:0030991)
0.2 5.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 3.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 6.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 2.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 59.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.2 1.6 GO:0031931 TORC1 complex(GO:0031931)
0.2 2.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.2 1.9 GO:0070652 HAUS complex(GO:0070652)
0.2 0.9 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.2 0.6 GO:1902560 GMP reductase complex(GO:1902560)
0.2 0.9 GO:0048179 activin receptor complex(GO:0048179)
0.2 0.4 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.2 2.3 GO:0000801 central element(GO:0000801)
0.2 1.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 13.1 GO:0005776 autophagosome(GO:0005776)
0.2 1.6 GO:1990023 mitotic spindle midzone(GO:1990023)
0.2 3.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.2 2.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 3.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.2 14.2 GO:0031985 Golgi cisterna(GO:0031985)
0.2 3.1 GO:0005614 interstitial matrix(GO:0005614)
0.2 0.6 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.2 3.9 GO:0046930 pore complex(GO:0046930)
0.1 6.3 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 1.0 GO:0016589 NURF complex(GO:0016589)
0.1 2.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 3.9 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.4 GO:0005682 U5 snRNP(GO:0005682)
0.1 1.5 GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177)
0.1 1.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.8 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 1.1 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 0.9 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 3.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 29.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 1.5 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 0.7 GO:0042581 specific granule(GO:0042581)
0.1 7.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 11.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.7 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.9 GO:0070187 telosome(GO:0070187)
0.1 5.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 28.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 5.6 GO:0042641 actomyosin(GO:0042641)
0.1 2.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.9 GO:0098645 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 0.5 GO:0005796 Golgi lumen(GO:0005796)
0.1 10.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 13.8 GO:0005840 ribosome(GO:0005840)
0.1 69.8 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 1.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.8 GO:0031082 BLOC complex(GO:0031082)
0.1 0.5 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.8 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 5.1 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 3.3 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 0.5 GO:0030914 STAGA complex(GO:0030914)
0.1 0.4 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 1.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 6.8 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 4.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 2.5 GO:0000795 synaptonemal complex(GO:0000795)
0.1 1.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.1 GO:1990423 RZZ complex(GO:1990423)
0.1 160.2 GO:0070062 extracellular exosome(GO:0070062)
0.1 0.8 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 1.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 2.8 GO:0000776 kinetochore(GO:0000776)
0.1 0.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.6 GO:0071564 npBAF complex(GO:0071564)
0.1 4.1 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.1 12.2 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1 0.8 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 2.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 1.6 GO:0005811 lipid particle(GO:0005811)
0.0 16.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.7 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 0.3 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 6.9 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 2.0 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.3 GO:0005643 nuclear pore(GO:0005643)
0.0 0.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.4 GO:0055037 recycling endosome(GO:0055037)
0.0 0.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 1.8 GO:0005774 vacuolar membrane(GO:0005774)
0.0 127.0 GO:0016021 integral component of membrane(GO:0016021)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.6 GO:0005581 collagen trimer(GO:0005581)
0.0 0.0 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.9 26.6 GO:0045550 geranylgeranyl reductase activity(GO:0045550)
7.6 22.9 GO:0004556 alpha-amylase activity(GO:0004556)
6.7 20.0 GO:0052853 very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
3.6 17.9 GO:0019770 IgG receptor activity(GO:0019770)
3.6 28.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
3.2 9.7 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
3.2 15.8 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
3.1 12.5 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
3.1 9.3 GO:0017042 glycosylceramidase activity(GO:0017042)
3.0 14.8 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
2.7 8.1 GO:0004925 prolactin receptor activity(GO:0004925)
2.6 7.8 GO:0031714 C5a anaphylatoxin chemotactic receptor binding(GO:0031714)
2.5 10.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
2.5 9.9 GO:0051870 methotrexate binding(GO:0051870)
2.3 9.4 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
2.3 62.1 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
2.1 8.3 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
2.1 12.3 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
2.0 20.1 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
1.9 7.6 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
1.9 5.7 GO:0004657 proline dehydrogenase activity(GO:0004657)
1.9 5.6 GO:0031871 proteinase activated receptor binding(GO:0031871)
1.8 7.3 GO:0019002 GMP binding(GO:0019002)
1.7 5.2 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
1.7 5.0 GO:0019961 interferon binding(GO:0019961)
1.6 9.7 GO:0030881 beta-2-microglobulin binding(GO:0030881)
1.6 6.5 GO:0000293 ferric-chelate reductase activity(GO:0000293)
1.5 7.6 GO:0004614 phosphoglucomutase activity(GO:0004614)
1.5 13.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
1.5 4.4 GO:0008405 arachidonic acid 11,12-epoxygenase activity(GO:0008405)
1.4 4.1 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
1.4 8.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
1.3 5.3 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
1.3 7.9 GO:0032027 myosin light chain binding(GO:0032027)
1.3 7.6 GO:0003840 gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
1.2 6.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
1.1 3.4 GO:0004793 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
1.1 6.8 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
1.1 5.5 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
1.1 4.4 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
1.1 4.4 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
1.1 3.2 GO:0001605 adrenomedullin receptor activity(GO:0001605)
1.1 3.2 GO:0047708 biotinidase activity(GO:0047708)
1.0 2.1 GO:0031686 A1 adenosine receptor binding(GO:0031686)
1.0 18.9 GO:0017081 chloride channel regulator activity(GO:0017081)
1.0 2.9 GO:0004924 oncostatin-M receptor activity(GO:0004924)
1.0 3.9 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312) PTB domain binding(GO:0051425)
0.9 2.8 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.9 11.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.9 11.8 GO:1990405 protein antigen binding(GO:1990405)
0.9 8.0 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.9 8.9 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.9 3.6 GO:0019776 Atg8 ligase activity(GO:0019776)
0.9 15.8 GO:0016595 glutamate binding(GO:0016595)
0.9 3.5 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.8 5.9 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.8 3.3 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.8 7.3 GO:0015266 protein channel activity(GO:0015266) P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.8 25.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.8 2.4 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.8 6.3 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.8 3.1 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.8 3.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.8 2.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.7 15.6 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.7 2.2 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.7 74.0 GO:0016503 pheromone receptor activity(GO:0016503)
0.7 5.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.7 8.7 GO:0005542 folic acid binding(GO:0005542)
0.7 14.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.7 4.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.7 3.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.7 2.7 GO:0008940 nitrate reductase activity(GO:0008940)
0.7 2.7 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.7 3.3 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.7 4.6 GO:0004064 arylesterase activity(GO:0004064)
0.7 18.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.6 1.3 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.6 8.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.6 5.7 GO:0005000 vasopressin receptor activity(GO:0005000)
0.6 3.7 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.6 0.6 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.6 9.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.6 1.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.6 13.2 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.6 2.4 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.6 7.1 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.6 4.7 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.6 5.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.6 2.9 GO:0045322 unmethylated CpG binding(GO:0045322)
0.6 2.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.6 10.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.6 3.4 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.6 40.3 GO:0003823 antigen binding(GO:0003823)
0.5 1.6 GO:0000991 transcription factor activity, core RNA polymerase II binding(GO:0000991)
0.5 7.0 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.5 2.7 GO:1990932 5.8S rRNA binding(GO:1990932)
0.5 2.7 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.5 14.9 GO:0008527 taste receptor activity(GO:0008527)
0.5 6.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.5 1.6 GO:0004825 methionine-tRNA ligase activity(GO:0004825)
0.5 7.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.5 10.8 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.5 2.0 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.5 8.0 GO:0035497 cAMP response element binding(GO:0035497)
0.5 14.9 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.5 3.5 GO:0004630 phospholipase D activity(GO:0004630)
0.5 2.9 GO:1990226 histone methyltransferase binding(GO:1990226)
0.5 3.4 GO:0033592 RNA strand annealing activity(GO:0033592)
0.5 1.4 GO:0015254 glycerol channel activity(GO:0015254)
0.5 3.8 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.5 6.3 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.5 1.9 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.5 2.9 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.5 9.8 GO:0017127 cholesterol transporter activity(GO:0017127)
0.5 5.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.5 1.8 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.5 1.8 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.5 2.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.4 1.8 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.4 4.4 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.4 2.6 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.4 2.2 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.4 9.0 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.4 0.4 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.4 5.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.4 4.9 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.4 5.3 GO:0016805 dipeptidase activity(GO:0016805)
0.4 10.7 GO:0042287 MHC protein binding(GO:0042287)
0.4 9.0 GO:0051861 glycolipid binding(GO:0051861)
0.4 1.6 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.4 3.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.4 3.1 GO:0051525 NFAT protein binding(GO:0051525)
0.4 5.0 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.4 1.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.4 4.6 GO:0070402 NADPH binding(GO:0070402)
0.4 2.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.4 6.6 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.4 0.7 GO:0015616 DNA translocase activity(GO:0015616)
0.4 1.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.4 2.8 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.3 1.4 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.3 4.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.3 1.0 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.3 1.7 GO:0019862 IgA binding(GO:0019862)
0.3 3.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174) superoxide-generating NADPH oxidase activity(GO:0016175)
0.3 1.4 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.3 3.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.3 4.9 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.3 3.6 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.3 3.5 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.3 0.9 GO:0001847 opsonin receptor activity(GO:0001847)
0.3 5.5 GO:0016504 peptidase activator activity(GO:0016504)
0.3 2.1 GO:0003896 DNA primase activity(GO:0003896)
0.3 1.5 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.3 2.4 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.3 5.3 GO:0008483 transaminase activity(GO:0008483)
0.3 2.6 GO:0001846 opsonin binding(GO:0001846)
0.3 1.5 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.3 1.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.3 16.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.3 2.0 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.3 1.1 GO:0000405 bubble DNA binding(GO:0000405)
0.3 1.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.3 1.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.3 3.6 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.3 0.6 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.3 1.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.3 21.0 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.3 1.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.3 1.5 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.3 4.0 GO:0044548 S100 protein binding(GO:0044548)
0.2 1.0 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.2 1.2 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.2 1.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 2.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2 3.3 GO:0070410 co-SMAD binding(GO:0070410)
0.2 1.4 GO:0033691 sialic acid binding(GO:0033691)
0.2 4.2 GO:0005522 profilin binding(GO:0005522)
0.2 4.6 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.2 1.4 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.2 0.9 GO:0017002 activin receptor activity, type I(GO:0016361) activin-activated receptor activity(GO:0017002)
0.2 4.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 4.5 GO:0004601 peroxidase activity(GO:0004601)
0.2 1.8 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.2 1.7 GO:0015925 galactosidase activity(GO:0015925)
0.2 0.6 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.2 4.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 2.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.2 5.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 1.0 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.2 0.8 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.2 6.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.2 1.6 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.2 5.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 3.9 GO:0015288 porin activity(GO:0015288)
0.2 1.0 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 4.1 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 3.1 GO:0051400 BH domain binding(GO:0051400)
0.2 3.1 GO:0071949 FAD binding(GO:0071949)
0.2 1.1 GO:0098821 BMP receptor activity(GO:0098821)
0.2 2.3 GO:0008097 5S rRNA binding(GO:0008097)
0.2 1.7 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.2 5.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 4.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 2.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.2 0.6 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.2 4.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 17.9 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.2 1.4 GO:0016421 CoA carboxylase activity(GO:0016421)
0.2 5.4 GO:0036002 pre-mRNA binding(GO:0036002)
0.2 1.6 GO:0019841 retinol binding(GO:0019841)
0.2 1.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.2 4.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 9.5 GO:0051287 NAD binding(GO:0051287)
0.2 7.3 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.2 68.0 GO:0005525 GTP binding(GO:0005525)
0.2 47.4 GO:0030246 carbohydrate binding(GO:0030246)
0.2 4.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 2.3 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.2 2.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 1.4 GO:0042165 neurotransmitter binding(GO:0042165)
0.2 1.6 GO:0008061 chitin binding(GO:0008061)
0.2 4.3 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.2 0.5 GO:0005119 smoothened binding(GO:0005119)
0.2 6.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 0.8 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 1.4 GO:0017136 NAD-dependent histone deacetylase activity(GO:0017136) histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) NAD-dependent protein deacetylase activity(GO:0034979)
0.2 0.5 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.2 0.3 GO:0016882 cyclo-ligase activity(GO:0016882)
0.2 3.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 1.0 GO:0004111 creatine kinase activity(GO:0004111)
0.1 1.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 2.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 1.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.7 GO:0055104 ligase inhibitor activity(GO:0055104) large ribosomal subunit rRNA binding(GO:0070180) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 13.4 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.1 4.0 GO:0070888 E-box binding(GO:0070888)
0.1 54.5 GO:0005549 odorant binding(GO:0005549)
0.1 5.4 GO:0070330 aromatase activity(GO:0070330)
0.1 0.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 8.3 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 1.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.6 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 1.1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 2.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 5.7 GO:0035064 methylated histone binding(GO:0035064)
0.1 6.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 1.8 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 2.1 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 27.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 0.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 2.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.3 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 0.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 1.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.6 GO:0017040 ceramidase activity(GO:0017040)
0.1 19.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.6 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 0.4 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 1.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 80.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 2.1 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 2.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 10.7 GO:0042393 histone binding(GO:0042393)
0.1 5.4 GO:0097110 scaffold protein binding(GO:0097110)
0.1 0.7 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.9 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 1.0 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 1.5 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1 2.1 GO:0030515 snoRNA binding(GO:0030515)
0.1 2.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 1.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 4.7 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 0.2 GO:0015292 uniporter activity(GO:0015292)
0.1 0.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.2 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.1 1.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 1.4 GO:0016209 antioxidant activity(GO:0016209)
0.1 2.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 10.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 2.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.1 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.3 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.1 1.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.4 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 1.5 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 2.6 GO:0035326 enhancer binding(GO:0035326)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.5 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 1.7 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.2 GO:0004945 angiotensin type II receptor activity(GO:0004945) endothelin receptor activity(GO:0004962)
0.0 1.1 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 7.3 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.8 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 1.2 GO:0017046 peptide hormone binding(GO:0017046)
0.0 9.2 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.9 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.2 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.7 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 1.2 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 25.2 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.7 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 1.8 GO:0051087 chaperone binding(GO:0051087)
0.0 7.2 GO:0045296 cadherin binding(GO:0045296)
0.0 0.1 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812)
0.0 0.5 GO:0017171 serine-type peptidase activity(GO:0008236) serine hydrolase activity(GO:0017171)
0.0 0.5 GO:0000049 tRNA binding(GO:0000049)
0.0 0.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.5 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.9 GO:0002039 p53 binding(GO:0002039)
0.0 0.6 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 0.1 GO:0035375 zymogen binding(GO:0035375)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.1 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 0.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.3 GO:0016896 3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0 3.8 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 1.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.7 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.0 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 17.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.8 2.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.6 7.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.6 32.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.6 9.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.5 3.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.5 1.5 PID IL5 PATHWAY IL5-mediated signaling events
0.4 6.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.4 24.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.4 7.0 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.3 3.8 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.3 22.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.3 21.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.3 12.9 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.3 2.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.3 13.1 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.3 4.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.2 1.0 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.2 7.6 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.2 8.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.2 5.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.2 10.7 PID RHOA PATHWAY RhoA signaling pathway
0.2 4.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.2 1.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.2 6.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 5.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.2 3.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 3.9 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.2 4.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2 4.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.2 4.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.2 4.7 PID RAS PATHWAY Regulation of Ras family activation
0.2 2.8 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.2 3.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 24.5 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.2 3.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.2 5.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.2 9.2 PID E2F PATHWAY E2F transcription factor network
0.2 6.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.2 1.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2 3.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.2 4.0 PID ARF6 PATHWAY Arf6 signaling events
0.2 2.3 ST ADRENERGIC Adrenergic Pathway
0.2 10.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.2 4.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.2 2.0 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.2 5.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 2.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 2.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 8.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 1.4 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 1.5 PID CD40 PATHWAY CD40/CD40L signaling
0.1 3.6 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 1.9 PID BCR 5PATHWAY BCR signaling pathway
0.1 1.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 3.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 2.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 1.4 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 2.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 2.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 1.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 0.9 PID ALK2 PATHWAY ALK2 signaling events
0.1 1.0 PID MYC PATHWAY C-MYC pathway
0.1 0.5 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.1 1.5 PID FGF PATHWAY FGF signaling pathway
0.1 12.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 0.9 PID BARD1 PATHWAY BARD1 signaling events
0.1 1.0 PID CDC42 PATHWAY CDC42 signaling events
0.1 0.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 1.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.5 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.1 PID BMP PATHWAY BMP receptor signaling
0.0 1.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.1 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.6 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.5 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.4 PID P73PATHWAY p73 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 29.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
1.7 15.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
1.2 15.8 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
1.0 15.9 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.9 13.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.9 44.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.8 24.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.8 4.9 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.8 15.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.8 4.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.8 9.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.8 9.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.8 13.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.6 7.0 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.6 7.0 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.6 6.9 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.6 21.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.5 5.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.5 14.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.5 3.5 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.5 1.5 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.5 17.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.4 8.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.4 6.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.4 14.0 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.4 7.5 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.4 8.1 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.4 8.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.4 7.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.4 9.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.4 6.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.3 19.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.3 8.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.3 3.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.3 12.0 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.3 5.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.3 5.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.3 3.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.3 3.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.3 3.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.3 5.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.3 5.0 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.3 5.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.3 5.1 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.3 4.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.3 1.8 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.3 5.2 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.3 3.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.3 2.0 REACTOME DEFENSINS Genes involved in Defensins
0.3 5.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.2 4.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.2 13.0 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.2 2.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 12.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.2 5.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 5.5 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.2 3.4 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.2 3.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.2 2.8 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.2 1.0 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 10.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 6.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 1.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.2 7.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2 3.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 2.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 6.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.2 3.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 2.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 1.8 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 9.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 2.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.2 10.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.2 6.7 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.2 6.4 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.2 3.5 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 1.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 2.2 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.1 1.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 2.6 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 2.0 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 3.7 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 5.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 2.7 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.1 3.8 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.1 1.4 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 2.5 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 2.9 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 2.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 3.1 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.0 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 5.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 1.7 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.1 1.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 1.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 2.4 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 9.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.7 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1 1.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 0.8 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 3.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 2.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 5.7 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.1 1.1 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.7 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 3.6 REACTOME SIGNALING BY THE B CELL RECEPTOR BCR Genes involved in Signaling by the B Cell Receptor (BCR)
0.0 0.8 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 2.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.5 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.5 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.3 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME PURINE METABOLISM Genes involved in Purine metabolism
0.0 0.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling