Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation
Downloads

Results for Klf16_Sp8

Z-value: 2.51

Motif logo

Transcription factors associated with Klf16_Sp8

Gene Symbol Gene ID Gene Info
ENSRNOG00000033694 Kruppel-like factor 16
ENSRNOG00000005943 Sp8 transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Klf16rn6_v1_chr7_+_12006710_12006710-0.446.7e-17Click!
Sp8rn6_v1_chr6_+_146784915_146784915-0.226.7e-05Click!

Activity profile of Klf16_Sp8 motif

Sorted Z-values of Klf16_Sp8 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_36320461 185.52 ENSRNOT00000023659
steroid 5 alpha-reductase 1
chr13_-_50499060 156.41 ENSRNOT00000065347
ENSRNOT00000076924
ethanolamine kinase 2
chr8_-_22937909 131.40 ENSRNOT00000015684
transmembrane protein 205
chr7_-_12246729 130.00 ENSRNOT00000044030
receptor accessory protein 6
chrX_-_54303729 115.47 ENSRNOT00000087919
ENSRNOT00000064340
ENSRNOT00000051249
ENSRNOT00000087547
glycerol kinase
chr16_-_32868680 113.82 ENSRNOT00000015974
ENSRNOT00000082392
aminoadipate aminotransferase
chr6_-_108167185 110.45 ENSRNOT00000015545
aldehyde dehydrogenase 6 family, member A1
chr1_-_80666566 107.61 ENSRNOT00000082125
ENSRNOT00000025388
nectin cell adhesion molecule 2
chr3_-_176144531 102.70 ENSRNOT00000082266
transcription factor like 5
chr1_-_80599572 99.23 ENSRNOT00000024832
apolipoprotein C4
chr3_+_151032952 95.88 ENSRNOT00000064013
acyl-CoA synthetase short-chain family member 2
chr3_-_10375826 93.96 ENSRNOT00000093365
argininosuccinate synthase 1
chr12_-_22194287 93.33 ENSRNOT00000082895
ENSRNOT00000001905
transferrin receptor 2
chr7_+_12247498 90.64 ENSRNOT00000022358
proprotein convertase subtilisin/kexin type 4
chr7_+_12043794 85.69 ENSRNOT00000039813
ATPase phospholipid transporting 8B3
chr7_-_119623072 85.28 ENSRNOT00000050511
thiosulfate sulfurtransferase
chr5_+_154598758 78.95 ENSRNOT00000015776
transcription elongation factor A3
chr7_+_28066635 78.67 ENSRNOT00000005844
phenylalanine hydroxylase
chr12_+_12227010 77.66 ENSRNOT00000060843
ENSRNOT00000092610
BAI1-associated protein 2-like 1
chr8_-_116422366 76.00 ENSRNOT00000023623
solute carrier family 38, member 3
chr16_+_20521956 75.84 ENSRNOT00000026597
pyroglutamyl-peptidase I
chr18_-_51651267 75.51 ENSRNOT00000020325
aldehyde dehydrogenase 7 family, member A1
chr1_-_256813711 75.04 ENSRNOT00000021055
retinol binding protein 4
chr17_+_76306585 74.41 ENSRNOT00000065978
dehydrogenase E1 and transketolase domain containing 1
chr4_+_153217782 74.29 ENSRNOT00000015499
CECR2, histone acetyl-lysine reader
chr15_-_84748525 73.95 ENSRNOT00000090009
Kruppel-like factor 12
chr2_-_23256158 73.61 ENSRNOT00000015336
betaine-homocysteine S-methyltransferase
chr10_+_89376530 72.35 ENSRNOT00000028089
Rho family GTPase 2
chr1_+_219759183 69.29 ENSRNOT00000026316
pyruvate carboxylase
chr15_-_19733967 69.08 ENSRNOT00000012036
glucosamine-phosphate N-acetyltransferase 1
chr2_+_21931493 68.11 ENSRNOT00000018259
dihydrofolate reductase
chr6_+_127400585 67.86 ENSRNOT00000087429
protein phosphatase 4, regulatory subunit 4
chr1_-_80609836 66.96 ENSRNOT00000091647
ENSRNOT00000046169
apolipoprotein C1
chr17_-_417480 66.63 ENSRNOT00000023685
fructose-bisphosphatase 1
chr1_-_216663720 66.45 ENSRNOT00000078944
ENSRNOT00000077409
cyclin-dependent kinase inhibitor 1C
chr7_+_2605719 65.25 ENSRNOT00000018737
glutaminase 2
chr12_+_19599834 65.08 ENSRNOT00000092039
ENSRNOT00000042006
stromal antigen 3
chr19_+_23389375 64.62 ENSRNOT00000018629
spalt-like transcription factor 1
chr5_-_134207847 64.56 ENSRNOT00000083686
ENSRNOT00000088209
ENSRNOT00000051252
cytochrome P450, family 4, subfamily a, polypeptide 2
chr13_+_85580828 63.79 ENSRNOT00000005611
aldehyde dehydrogenase 9 family, member A1
chr5_+_126164674 62.57 ENSRNOT00000009402
24-dehydrocholesterol reductase
chr1_+_217018916 62.54 ENSRNOT00000028195
ENSRNOT00000078979
7-dehydrocholesterol reductase
chr6_-_127653124 61.82 ENSRNOT00000047324
serpin family A member 11
chr3_-_138116664 60.89 ENSRNOT00000055602
ribosome binding protein 1
chr8_+_22937916 60.86 ENSRNOT00000088255
ENSRNOT00000049993
coiled-coil domain containing 159
chr20_-_14193690 60.70 ENSRNOT00000058237
beta-ureidopropionase 1
chr19_-_37916813 60.46 ENSRNOT00000026585
lecithin cholesterol acyltransferase
chr2_-_264293010 59.52 ENSRNOT00000082532
ENSRNOT00000067843
cystathionine gamma-lyase
chr1_-_214202853 59.43 ENSRNOT00000022954
lamin tail domain containing 2
chr10_+_109665682 59.18 ENSRNOT00000054963
solute carrier family 25 member 10
chrY_-_1403422 58.53 ENSRNOT00000093067
ubiquitin specific peptidase 9, Y-linked
chr7_+_26375866 57.86 ENSRNOT00000059639
aldehyde dehydrogenase 1 family, member L2
chr1_+_243477493 57.66 ENSRNOT00000021779
ENSRNOT00000085356
doublesex and mab-3 related transcription factor 1
chr5_+_60528997 56.74 ENSRNOT00000051445
glyoxylate and hydroxypyruvate reductase
chr10_+_4951557 56.68 ENSRNOT00000003451
protamine 3
chr20_+_13799102 54.93 ENSRNOT00000001669
glutathione S-transferase theta 1
chr1_-_78573374 54.63 ENSRNOT00000090519
Rho GTPase activating protein 35
chr6_+_111176798 54.44 ENSRNOT00000072215
glutathione S-transferase zeta 1
chr19_+_26106838 54.20 ENSRNOT00000035987
hook microtubule-tethering protein 2
chr7_+_126619196 54.20 ENSRNOT00000030082
peroxisome proliferator activated receptor alpha
chr5_+_154552195 54.15 ENSRNOT00000072864
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr15_-_3435888 54.12 ENSRNOT00000016709
adenosine kinase
chr4_+_117679342 53.45 ENSRNOT00000021272
folliculogenesis specific bHLH transcription factor
chr12_-_21832813 52.88 ENSRNOT00000075280
claudin 3
chr20_+_28989491 52.85 ENSRNOT00000074524
phospholipase A2, group XIIB
chr3_-_5481144 52.43 ENSRNOT00000078429
surfeit 4
chr2_+_78825074 52.39 ENSRNOT00000032027
membrane associated ring-CH-type finger 11
chr2_+_77868412 51.43 ENSRNOT00000065897
ENSRNOT00000014022
myosin X
chr8_+_64364741 51.39 ENSRNOT00000082840
CUGBP, Elav-like family member 6
chr6_-_94834908 51.31 ENSRNOT00000006284
trans-L-3-hydroxyproline dehydratase
chr3_+_5481522 51.25 ENSRNOT00000031316
serine/threonine kinase-like domain containing 1
chrX_+_123205869 51.09 ENSRNOT00000017101
ENSRNOT00000079231
progesterone receptor membrane component 1
chr3_-_62524996 50.70 ENSRNOT00000002114
nuclear factor, erythroid 2-like 2
chr1_-_247476827 50.68 ENSRNOT00000021298
insulin-like 6
chr1_-_101210675 50.65 ENSRNOT00000028082
dickkopf like acrosomal protein 1
chr17_+_21382455 50.54 ENSRNOT00000019756
ELOVL fatty acid elongase 2
chr2_-_185168476 50.10 ENSRNOT00000093447
family with sequence similarity 160, member A1
chr8_+_127735258 49.93 ENSRNOT00000015888
villin-like
chr14_+_70164650 49.91 ENSRNOT00000004385
quinoid dihydropteridine reductase
chr2_-_210703606 49.89 ENSRNOT00000077563
glutathione S-transferase, mu 6-like
chrY_+_422855 49.36 ENSRNOT00000092178
ubiquitin-activating enzyme, Chr Y
chr1_+_98440186 49.34 ENSRNOT00000024150
IgLON family member 5
chr15_-_41890716 48.97 ENSRNOT00000020419
SPRY domain containing 7
chr7_-_34406318 48.83 ENSRNOT00000007331
amidohydrolase domain containing 1
chr5_+_136112417 48.82 ENSRNOT00000025990
transmembrane protein 53
chr7_+_12314848 48.77 ENSRNOT00000028969
guanidinoacetate N-methyltransferase
chr10_-_103826448 48.71 ENSRNOT00000085636
ferredoxin reductase
chr19_-_22632071 48.51 ENSRNOT00000077275
glutamic--pyruvic transaminase 2
chr19_-_37370429 48.34 ENSRNOT00000022497
potassium channel tetramerization domain containing 19
chr1_-_273758247 47.38 ENSRNOT00000033148
X-prolyl aminopeptidase 1
chr1_+_82169620 47.30 ENSRNOT00000088955
ENSRNOT00000068251
proline rich 19
chrX_+_69730242 46.70 ENSRNOT00000075980
ENSRNOT00000076425
ectodysplasin-A
chr1_-_263803150 46.51 ENSRNOT00000017840
cytochrome P450, family 2, subfamily c, polypeptide 23
chr6_-_128567198 46.49 ENSRNOT00000065529
calmin
chr7_+_34326087 46.26 ENSRNOT00000006971
histidine ammonia lyase
chr17_+_76002275 46.15 ENSRNOT00000092665
ENSRNOT00000086701
enoyl CoA hydratase domain containing 3
chr14_+_85113578 46.04 ENSRNOT00000011158
nipsnap homolog 1
chr10_+_56546710 46.04 ENSRNOT00000023003
Y box binding protein 2
chr18_+_79773608 45.79 ENSRNOT00000088484
zinc finger protein 516
chr2_-_21931720 45.61 ENSRNOT00000018449
mutS homolog 3
chr2_-_23289266 45.50 ENSRNOT00000061708
betaine-homocysteine S-methyltransferase 2
chr16_-_20641908 45.28 ENSRNOT00000026846
elongation factor for RNA polymerase II
chr8_-_114853103 45.13 ENSRNOT00000074595
glycerate kinase
chr9_-_61974898 45.12 ENSRNOT00000091519
boule homolog, RNA binding protein
chr9_-_64573076 44.52 ENSRNOT00000084658
protein boule-like
chr3_+_170354141 44.49 ENSRNOT00000005901
family with sequence similarity 210, member B
chr18_-_28454756 44.42 ENSRNOT00000040091
spermatogenesis associated 24
chr8_+_81766041 44.26 ENSRNOT00000032280
one cut homeobox 1
chr10_-_61772250 44.13 ENSRNOT00000092338
ENSRNOT00000085394
ENSRNOT00000046110
serine racemase
chr1_-_226657408 44.13 ENSRNOT00000028102
triokinase and FMN cyclase
chr16_+_47717951 43.99 ENSRNOT00000018689
inhibitor of growth family, member 2
chr1_+_226687258 43.91 ENSRNOT00000079679
von Willebrand factor C and EGF domains
chr10_+_56445647 43.78 ENSRNOT00000056870
transmembrane protein 256
chr8_-_94368834 43.54 ENSRNOT00000078977
malic enzyme 1
chr2_-_260148589 43.53 ENSRNOT00000013238
acyl-CoA dehydrogenase, C-4 to C-12 straight chain
chr18_-_61707307 43.47 ENSRNOT00000085784
ENSRNOT00000032047
lectin, mannose-binding, 1
chr1_-_107373807 43.21 ENSRNOT00000056024
small VCP interacting protein
chr14_+_115166416 43.12 ENSRNOT00000088916
ENSRNOT00000078329
proteasome activator subunit 4
chr14_-_16979760 43.01 ENSRNOT00000003020
starch binding domain 1
chr1_+_166893734 43.00 ENSRNOT00000026702
paired-like homeobox 2a
chr2_-_53413638 42.80 ENSRNOT00000021081
growth hormone receptor
chr11_+_30363280 42.50 ENSRNOT00000002885
superoxide dismutase 1, soluble
chr6_-_7058314 42.49 ENSRNOT00000045996
3-hydroxyanthranilate 3,4-dioxygenase
chr11_+_7210209 42.38 ENSRNOT00000076695
1,4-alpha-glucan branching enzyme 1
chr1_-_273758442 41.94 ENSRNOT00000088016
X-prolyl aminopeptidase 1
chr1_+_216677373 41.85 ENSRNOT00000027925
solute carrier family 22, member 18
chr5_-_164971903 41.75 ENSRNOT00000067059
F-box protein 44
chr9_+_53906073 41.60 ENSRNOT00000017813
Ngfi-A binding protein 1
chr16_-_7026540 41.56 ENSRNOT00000051751
inter-alpha trypsin inhibitor, heavy chain 1
chr9_-_16612136 41.44 ENSRNOT00000023495
male-enhanced antigen 1
chr15_+_46008613 41.41 ENSRNOT00000066864
ENSRNOT00000080537
WD repeat and FYVE domain containing 2
chr15_-_46367302 41.36 ENSRNOT00000032089
farnesyl diphosphate farnesyl transferase 1
chr5_-_169167831 41.32 ENSRNOT00000012407
PHD finger protein 13
chr8_-_50526843 41.03 ENSRNOT00000092188

chr1_-_92069160 41.03 ENSRNOT00000039115
dpy-19-like 3 (C. elegans)
chrX_+_157095937 40.92 ENSRNOT00000091792
B-cell receptor-associated protein 31
chr1_-_163328591 40.89 ENSRNOT00000034843
tsukushi, small leucine rich proteoglycan
chr19_-_49532811 40.67 ENSRNOT00000015967
glycine cleavage system protein H
chr2_+_23289374 40.57 ENSRNOT00000090666
ENSRNOT00000032783
dimethylglycine dehydrogenase
chr5_+_61565064 40.57 ENSRNOT00000090186
tudor domain containing 7
chr8_-_47529689 40.41 ENSRNOT00000012826
out at first homolog
chr11_+_87204175 40.34 ENSRNOT00000000306
solute carrier family 25 member 1
chr17_+_77167740 40.18 ENSRNOT00000042881
optineurin
chr2_+_195617021 40.15 ENSRNOT00000067042
ENSRNOT00000036656
RAR-related orphan receptor C
leucine rich repeat and Ig domain containing 4
chr9_-_64573660 39.95 ENSRNOT00000021299
protein boule-like
chr2_-_128002005 39.84 ENSRNOT00000018796
progesterone receptor membrane component 2
chr9_+_95501778 39.77 ENSRNOT00000086805
secreted phosphoprotein 2
chr4_-_157009674 39.56 ENSRNOT00000071625
peroxisomal biogenesis factor 5
chr9_-_92435363 39.47 ENSRNOT00000093735
ENSRNOT00000022822
ENSRNOT00000093245
thyroid hormone receptor interactor 12
chr19_+_15195565 39.33 ENSRNOT00000090865
ENSRNOT00000078874
carboxylesterase 1D
chr8_-_40078165 39.27 ENSRNOT00000014866
sperm autoantigenic protein 17
chr1_+_201981357 39.19 ENSRNOT00000027999
acyl-CoA dehydrogenase, short/branched chain
chr1_-_80615704 38.63 ENSRNOT00000041891
apolipoprotein E
chr19_+_15033108 38.62 ENSRNOT00000021812
carboxylesterase 1D
chr5_-_127523089 38.57 ENSRNOT00000016954
carnitine palmitoyltransferase 2
chr7_+_94795214 38.51 ENSRNOT00000005722
DEP domain containing MTOR-interacting protein
chr5_+_9279970 38.43 ENSRNOT00000067977
myeloblastosis oncogene-like 1
chr16_-_81797815 38.38 ENSRNOT00000026666
protein Z, vitamin K-dependent plasma glycoprotein
chr18_-_15167311 38.36 ENSRNOT00000021061
ring finger protein 138
chr9_-_61975640 38.36 ENSRNOT00000085744
boule homolog, RNA binding protein
chr8_+_106449321 38.34 ENSRNOT00000018622
retinol binding protein 1
chr10_+_83954279 38.18 ENSRNOT00000006594
tubulin tyrosine ligase like 6
chr4_+_27175243 38.12 ENSRNOT00000009985
cytochrome P450, family 51
chr1_+_218632764 38.11 ENSRNOT00000019861
testis expressed metallothionein like protein
chr7_-_11186130 38.04 ENSRNOT00000075038
small integral membrane protein 24
chr14_+_44479614 37.80 ENSRNOT00000003691
UDP-glucose 6-dehydrogenase
chr10_+_14240219 37.57 ENSRNOT00000020233
insulin-like growth factor binding protein, acid labile subunit
chr19_+_15294248 37.43 ENSRNOT00000024622
carboxylesterase 1F
chr12_+_15890170 37.43 ENSRNOT00000001654
G protein subunit alpha 12
chr19_+_25983169 37.42 ENSRNOT00000004404
synaptonemal complex central element protein 2
chr3_+_151553578 37.39 ENSRNOT00000045484
ERGIC and golgi 3
chr5_-_78379346 37.35 ENSRNOT00000020625
aminolevulinate dehydratase
chr13_-_37287458 37.31 ENSRNOT00000003391
insulin induced gene 2
chr18_+_59830363 37.26 ENSRNOT00000082650
ENSRNOT00000078378
one cut domain, family member 2
chr16_-_54513349 37.25 ENSRNOT00000014809
ENSRNOT00000015127
solute carrier family 7 member 2
chr5_-_136112344 37.25 ENSRNOT00000050195
RGD1563714
chr1_+_198690794 37.17 ENSRNOT00000023999
zinc finger protein 771
chr4_+_121612332 37.16 ENSRNOT00000077374
ENSRNOT00000084494
thioredoxin reductase 3
chr10_-_13580821 37.05 ENSRNOT00000009735
netrin 3
chr1_+_40086470 36.81 ENSRNOT00000021895
iodotyrosine deiodinase
chr3_+_134413170 36.70 ENSRNOT00000074338

chr3_+_95233874 36.69 ENSRNOT00000079743
hypothetical protein LOC691083
chrX_-_33665821 36.69 ENSRNOT00000066676
RB binding protein 7, chromatin remodeling factor
chr9_-_80295446 36.62 ENSRNOT00000023769
transition protein 1
chr1_+_72636959 36.40 ENSRNOT00000023489
interleukin 11
chr17_+_18029124 36.38 ENSRNOT00000022085
thiopurine S-methyltransferase
chr16_+_74865516 36.33 ENSRNOT00000058072
ATPase copper transporting beta
chr12_+_16913312 36.27 ENSRNOT00000001718
transmembrane protein 184A
chr6_+_37144787 36.20 ENSRNOT00000075503
RAD51 associated protein 2
chr17_+_78817529 36.03 ENSRNOT00000021918
meiosis/spermiogenesis associated 1
chr19_+_58746313 35.88 ENSRNOT00000026986
mitogen-activated protein kinase kinase kinase 21
chr6_+_128973956 35.88 ENSRNOT00000075399
family with sequence similarity 181, member A
chr8_-_27852996 35.86 ENSRNOT00000037790
galactosidase, beta 1-like 2
chr16_-_81834945 35.79 ENSRNOT00000037806
coagulation factor VII
chrX_+_71272042 35.48 ENSRNOT00000076034
ENSRNOT00000076816
gap junction protein, beta 1
chr9_+_112293388 35.39 ENSRNOT00000020767
mannosidase, alpha, class 2A, member 1
chr12_+_36734372 35.36 ENSRNOT00000001301
scavenger receptor class B, member 1
chr3_-_94686989 35.28 ENSRNOT00000016677
DEP domain containing 7
chr10_+_103972888 35.27 ENSRNOT00000067838
potassium channel tetramerization domain containing 2
chr10_-_104748003 34.98 ENSRNOT00000042372
ENSRNOT00000046754
acyl-CoA oxidase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Klf16_Sp8

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
51.5 154.4 GO:0006574 valine catabolic process(GO:0006574)
47.6 142.7 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
44.8 134.3 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
41.7 125.1 GO:0000053 argininosuccinate metabolic process(GO:0000053)
38.1 114.2 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
37.8 113.4 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
37.6 112.8 GO:0016128 phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
35.6 106.7 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343)
34.6 276.8 GO:0006559 L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
31.7 95.1 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) formamide metabolic process(GO:0043606)
31.1 93.4 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
29.3 117.2 GO:0010915 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
28.9 86.8 GO:0009397 folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
28.5 85.6 GO:0046086 adenosine biosynthetic process(GO:0046086)
28.4 85.3 GO:0035928 rRNA import into mitochondrion(GO:0035928)
27.5 109.8 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
26.0 78.1 GO:0046865 isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
26.0 78.0 GO:0019541 acetate metabolic process(GO:0006083) propionate metabolic process(GO:0019541)
25.1 75.3 GO:1902024 histidine transport(GO:0015817) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
24.9 99.6 GO:0048252 lauric acid metabolic process(GO:0048252)
24.8 99.0 GO:0046351 disaccharide biosynthetic process(GO:0046351)
24.7 74.2 GO:0071422 succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
24.0 96.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
23.9 143.6 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
23.1 185.1 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
22.5 67.6 GO:2000384 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
22.3 22.3 GO:0032805 positive regulation of low-density lipoprotein particle receptor catabolic process(GO:0032805)
22.1 66.3 GO:0006543 glutamine catabolic process(GO:0006543)
21.8 65.3 GO:0009751 response to salicylic acid(GO:0009751)
20.5 82.2 GO:0019483 beta-alanine biosynthetic process(GO:0019483)
20.2 40.3 GO:0015746 citrate transport(GO:0015746)
19.9 39.9 GO:1902221 L-phenylalanine metabolic process(GO:0006558) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221)
19.7 19.7 GO:0046439 cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
19.6 78.2 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
19.1 57.2 GO:1905225 response to thyrotropin-releasing hormone(GO:1905225)
18.3 55.0 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
17.2 51.6 GO:0015920 lipopolysaccharide transport(GO:0015920)
17.2 103.1 GO:0034370 triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
16.6 16.6 GO:2000188 regulation of cholesterol homeostasis(GO:2000188)
16.6 49.7 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
16.4 131.2 GO:0009698 phenylpropanoid metabolic process(GO:0009698)
15.7 62.7 GO:0097069 cellular response to thyroxine stimulus(GO:0097069)
15.7 78.4 GO:0046146 tetrahydrobiopterin metabolic process(GO:0046146)
15.5 108.8 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
15.3 45.8 GO:0089718 amino acid import across plasma membrane(GO:0089718)
15.2 15.2 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
15.1 60.6 GO:0035565 regulation of pronephros size(GO:0035565)
14.9 29.7 GO:0016107 sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488)
14.8 44.5 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
14.8 44.3 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
14.7 44.1 GO:0046416 D-amino acid metabolic process(GO:0046416)
14.6 14.6 GO:0034971 histone H3-R17 methylation(GO:0034971)
14.6 43.9 GO:0007308 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
14.6 218.9 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
14.6 58.3 GO:0018992 germ-line sex determination(GO:0018992)
14.4 57.8 GO:0015879 carnitine transport(GO:0015879)
14.0 56.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
14.0 42.0 GO:0021558 trochlear nerve development(GO:0021558)
13.9 13.9 GO:0009436 glyoxylate catabolic process(GO:0009436)
13.9 69.5 GO:0060903 positive regulation of meiosis I(GO:0060903)
13.9 41.6 GO:0010133 proline catabolic process(GO:0006562) proline catabolic process to glutamate(GO:0010133)
13.8 41.3 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
13.8 55.0 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
13.7 41.2 GO:0018916 nitrobenzene metabolic process(GO:0018916)
13.7 27.4 GO:0072719 cellular response to cisplatin(GO:0072719)
13.7 54.6 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
13.4 40.3 GO:0006565 L-serine catabolic process(GO:0006565)
13.4 215.1 GO:0042448 progesterone metabolic process(GO:0042448)
13.4 26.7 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
13.3 40.0 GO:0030091 protein repair(GO:0030091)
13.3 39.8 GO:0015680 intracellular copper ion transport(GO:0015680)
13.2 39.6 GO:0036166 phenotypic switching(GO:0036166)
13.0 38.9 GO:0098749 cerebellar neuron development(GO:0098749)
12.9 51.7 GO:1990402 embryonic liver development(GO:1990402)
12.8 38.5 GO:0021539 subthalamus development(GO:0021539)
12.7 12.7 GO:0002930 trabecular meshwork development(GO:0002930)
12.6 25.1 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
12.3 36.8 GO:0006570 tyrosine metabolic process(GO:0006570)
12.2 48.8 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
12.2 73.2 GO:0070541 response to platinum ion(GO:0070541)
12.0 35.9 GO:0042732 D-xylose metabolic process(GO:0042732)
11.8 35.5 GO:0071579 regulation of zinc ion transport(GO:0071579)
11.4 11.4 GO:0006538 glutamate catabolic process(GO:0006538)
11.4 45.4 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
11.3 45.1 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
11.2 44.7 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
11.0 44.1 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
11.0 32.9 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
10.9 32.8 GO:0006059 hexitol metabolic process(GO:0006059)
10.9 32.8 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
10.9 65.6 GO:0006069 ethanol oxidation(GO:0006069)
10.9 54.3 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
10.8 75.4 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
10.7 21.5 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
10.6 10.6 GO:0006553 lysine metabolic process(GO:0006553)
10.6 31.7 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
10.5 21.1 GO:0006526 arginine biosynthetic process(GO:0006526)
10.5 73.4 GO:0006577 amino-acid betaine metabolic process(GO:0006577)
10.4 41.7 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
10.4 20.8 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
10.4 41.5 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
10.2 30.5 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
10.1 10.1 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
10.1 50.6 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
10.0 39.8 GO:0010534 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
9.8 39.3 GO:0006741 NADP biosynthetic process(GO:0006741)
9.7 9.7 GO:0009216 purine deoxyribonucleoside triphosphate biosynthetic process(GO:0009216)
9.7 38.8 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
9.7 96.9 GO:0015886 heme transport(GO:0015886)
9.6 9.6 GO:0046544 development of secondary male sexual characteristics(GO:0046544)
9.6 67.1 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
9.6 28.7 GO:1901873 regulation of post-translational protein modification(GO:1901873)
9.6 19.1 GO:0043691 reverse cholesterol transport(GO:0043691)
9.5 19.0 GO:0006548 histidine catabolic process(GO:0006548)
9.4 18.9 GO:0071400 cellular response to oleic acid(GO:0071400)
9.4 328.2 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
9.4 56.2 GO:0006041 glucosamine metabolic process(GO:0006041)
9.4 28.1 GO:0070370 cellular heat acclimation(GO:0070370)
9.3 56.0 GO:0009078 alanine metabolic process(GO:0006522) pyruvate family amino acid metabolic process(GO:0009078) L-alanine metabolic process(GO:0042851)
9.3 18.7 GO:0046874 quinolinate metabolic process(GO:0046874)
9.3 37.2 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
9.3 27.8 GO:0060061 Spemann organizer formation(GO:0060061)
9.3 37.1 GO:1903334 positive regulation of protein folding(GO:1903334)
9.3 27.8 GO:0070634 transepithelial ammonium transport(GO:0070634)
9.2 27.6 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
9.1 45.6 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
9.1 45.6 GO:0030070 insulin processing(GO:0030070)
9.1 54.6 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
9.0 324.0 GO:0006695 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
8.9 26.8 GO:0042126 nitrate metabolic process(GO:0042126)
8.9 26.6 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
8.8 53.1 GO:0006528 asparagine metabolic process(GO:0006528)
8.8 26.5 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
8.8 43.8 GO:0060327 cytoplasmic actin-based contraction involved in cell motility(GO:0060327)
8.8 52.6 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
8.7 43.5 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
8.6 17.2 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
8.6 8.6 GO:0045764 positive regulation of cellular amino acid metabolic process(GO:0045764)
8.5 17.0 GO:1901856 negative regulation of cellular respiration(GO:1901856)
8.5 25.5 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
8.5 42.5 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
8.4 33.7 GO:0021526 medial motor column neuron differentiation(GO:0021526)
8.4 33.4 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
8.3 25.0 GO:0006552 leucine catabolic process(GO:0006552)
8.3 16.6 GO:0007356 thorax and anterior abdomen determination(GO:0007356)
8.3 16.5 GO:0016094 polyprenol biosynthetic process(GO:0016094)
8.3 16.5 GO:0006714 sesquiterpenoid metabolic process(GO:0006714)
8.2 33.0 GO:0000050 urea cycle(GO:0000050)
8.2 8.2 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
8.2 32.8 GO:0061073 ciliary body morphogenesis(GO:0061073)
8.2 32.6 GO:1901382 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
8.1 89.6 GO:0019363 nicotinamide nucleotide biosynthetic process(GO:0019359) pyridine nucleotide biosynthetic process(GO:0019363)
8.0 24.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
8.0 15.9 GO:1904612 response to 2,3,7,8-tetrachlorodibenzodioxine(GO:1904612)
7.9 39.5 GO:0006600 creatine metabolic process(GO:0006600)
7.9 23.6 GO:0006545 glycine biosynthetic process(GO:0006545)
7.8 7.8 GO:0061740 protein targeting to lysosome involved in chaperone-mediated autophagy(GO:0061740)
7.8 23.4 GO:1990743 protein sialylation(GO:1990743)
7.8 15.6 GO:0035937 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
7.8 54.5 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
7.8 147.8 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
7.7 30.9 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
7.7 23.0 GO:0090081 regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
7.6 30.4 GO:2000195 negative regulation of female gonad development(GO:2000195)
7.6 30.3 GO:0035772 interleukin-13-mediated signaling pathway(GO:0035772)
7.6 37.8 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
7.5 60.2 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
7.5 22.6 GO:0002397 MHC class I protein complex assembly(GO:0002397)
7.5 15.0 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
7.4 14.9 GO:0060468 prevention of polyspermy(GO:0060468)
7.4 22.3 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
7.4 14.9 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
7.4 44.5 GO:0090383 phagosome acidification(GO:0090383)
7.3 43.9 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
7.3 29.1 GO:0003253 cardiac neural crest cell migration involved in outflow tract morphogenesis(GO:0003253)
7.2 21.7 GO:1905204 septum secundum development(GO:0003285) negative regulation of connective tissue replacement(GO:1905204)
7.2 7.2 GO:1990379 lipid transport across blood brain barrier(GO:1990379)
7.1 71.3 GO:0001842 neural fold formation(GO:0001842)
7.1 7.1 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
7.1 14.2 GO:0009071 serine family amino acid catabolic process(GO:0009071)
7.1 21.2 GO:0034696 response to prostaglandin F(GO:0034696)
7.0 34.9 GO:1901475 pyruvate transmembrane transport(GO:1901475)
6.9 20.7 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
6.9 48.3 GO:0010815 bradykinin catabolic process(GO:0010815)
6.9 20.6 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
6.8 34.2 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
6.8 61.4 GO:0097501 stress response to metal ion(GO:0097501)
6.8 20.4 GO:0006106 fumarate metabolic process(GO:0006106)
6.8 6.8 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
6.7 20.2 GO:0044108 calcitriol biosynthetic process from calciol(GO:0036378) cellular alcohol metabolic process(GO:0044107) cellular alcohol biosynthetic process(GO:0044108)
6.7 20.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
6.7 46.8 GO:0043686 co-translational protein modification(GO:0043686)
6.7 20.0 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
6.7 13.3 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
6.6 19.8 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
6.6 46.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
6.6 19.8 GO:0072615 interleukin-17 secretion(GO:0072615)
6.6 19.7 GO:2000611 positive regulation of thyroid hormone generation(GO:2000611)
6.5 19.5 GO:0035711 T-helper 1 cell activation(GO:0035711)
6.5 25.9 GO:1904378 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
6.5 19.4 GO:0003342 proepicardium development(GO:0003342) septum transversum development(GO:0003343)
6.4 45.0 GO:0007290 spermatid nucleus elongation(GO:0007290)
6.4 25.7 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
6.3 31.6 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
6.3 37.8 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
6.3 18.8 GO:0018201 peptidyl-glycine modification(GO:0018201)
6.3 12.5 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
6.2 18.7 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
6.2 31.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
6.2 12.4 GO:0060155 platelet dense granule organization(GO:0060155)
6.2 111.7 GO:0015936 coenzyme A metabolic process(GO:0015936)
6.2 55.7 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
6.2 18.6 GO:0009407 toxin catabolic process(GO:0009407) mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) secondary metabolite catabolic process(GO:0090487) organic heteropentacyclic compound catabolic process(GO:1901377)
6.2 30.8 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
6.1 18.3 GO:0008211 glucocorticoid metabolic process(GO:0008211)
6.1 12.2 GO:0039019 pronephric nephron development(GO:0039019)
6.1 48.6 GO:0006776 vitamin A metabolic process(GO:0006776)
6.1 36.4 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
6.0 30.2 GO:0006105 succinate metabolic process(GO:0006105)
6.0 41.7 GO:0014886 transition between slow and fast fiber(GO:0014886)
5.9 53.4 GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042)
5.9 29.7 GO:0045218 zonula adherens maintenance(GO:0045218)
5.9 23.7 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
5.9 53.2 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
5.9 82.7 GO:0034498 early endosome to Golgi transport(GO:0034498)
5.9 11.8 GO:0048382 mesendoderm development(GO:0048382)
5.9 17.7 GO:1904056 regulation of cholangiocyte proliferation(GO:1904054) positive regulation of cholangiocyte proliferation(GO:1904056)
5.8 17.4 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
5.8 40.5 GO:0001920 negative regulation of receptor recycling(GO:0001920)
5.7 17.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
5.7 40.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
5.7 5.7 GO:0033483 gas homeostasis(GO:0033483)
5.7 28.4 GO:0009068 aspartate family amino acid catabolic process(GO:0009068)
5.6 117.6 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
5.6 11.2 GO:0015811 L-cystine transport(GO:0015811)
5.6 11.1 GO:0048793 pronephros development(GO:0048793)
5.5 22.2 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
5.5 27.6 GO:0009446 putrescine biosynthetic process(GO:0009446)
5.5 21.9 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
5.5 27.3 GO:0072240 DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240)
5.5 283.8 GO:0006635 fatty acid beta-oxidation(GO:0006635)
5.4 10.9 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
5.4 16.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
5.4 37.7 GO:0060720 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
5.3 16.0 GO:0030242 pexophagy(GO:0030242)
5.3 5.3 GO:0061017 hepatoblast differentiation(GO:0061017)
5.3 111.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
5.3 15.9 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
5.2 31.4 GO:0010044 response to aluminum ion(GO:0010044)
5.2 10.5 GO:0006011 UDP-glucose metabolic process(GO:0006011)
5.2 15.7 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
5.2 20.9 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
5.2 36.3 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
5.2 25.9 GO:1904970 brush border assembly(GO:1904970)
5.2 98.0 GO:0006101 citrate metabolic process(GO:0006101)
5.1 20.5 GO:1904975 response to bleomycin(GO:1904975)
5.1 5.1 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
5.1 45.9 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
5.1 10.2 GO:0051177 meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177)
5.1 30.4 GO:0006477 protein sulfation(GO:0006477)
5.1 45.5 GO:0002176 male germ cell proliferation(GO:0002176)
5.1 5.1 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
5.0 25.2 GO:1902774 late endosome to lysosome transport(GO:1902774)
5.0 35.2 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
5.0 5.0 GO:0009946 proximal/distal axis specification(GO:0009946)
5.0 40.0 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
5.0 20.0 GO:1902534 single-organism membrane invagination(GO:1902534)
5.0 29.9 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
5.0 14.9 GO:0034499 late endosome to Golgi transport(GO:0034499)
5.0 14.9 GO:0072752 cellular response to rapamycin(GO:0072752)
5.0 39.7 GO:0060687 regulation of branching involved in prostate gland morphogenesis(GO:0060687)
4.9 14.8 GO:0032258 CVT pathway(GO:0032258)
4.9 34.5 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
4.9 63.6 GO:0051013 microtubule severing(GO:0051013)
4.9 4.9 GO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769)
4.8 9.7 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
4.8 9.7 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
4.8 14.4 GO:0045054 constitutive secretory pathway(GO:0045054)
4.8 14.4 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
4.8 19.1 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
4.8 19.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
4.7 19.0 GO:0061107 seminal vesicle development(GO:0061107)
4.7 19.0 GO:0014028 notochord formation(GO:0014028)
4.7 9.5 GO:0018963 phthalate metabolic process(GO:0018963)
4.7 33.0 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
4.7 33.0 GO:0007144 female meiosis I(GO:0007144)
4.7 18.8 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
4.7 14.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
4.7 9.4 GO:0019660 fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
4.6 46.3 GO:0045792 negative regulation of cell size(GO:0045792)
4.6 4.6 GO:0007227 signal transduction downstream of smoothened(GO:0007227)
4.6 36.8 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
4.6 50.4 GO:0006108 malate metabolic process(GO:0006108)
4.6 32.0 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
4.6 22.8 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
4.5 22.7 GO:0048240 sperm capacitation(GO:0048240)
4.5 9.0 GO:0032364 oxygen homeostasis(GO:0032364)
4.5 4.5 GO:1903094 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
4.5 76.0 GO:0006855 drug transmembrane transport(GO:0006855)
4.5 102.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
4.4 17.8 GO:0030382 sperm mitochondrion organization(GO:0030382)
4.4 13.3 GO:0006710 androgen catabolic process(GO:0006710)
4.4 17.7 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
4.4 4.4 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
4.4 17.6 GO:0061743 motor learning(GO:0061743)
4.4 17.5 GO:0050893 sensory processing(GO:0050893)
4.4 30.6 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
4.4 8.8 GO:0003275 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
4.4 30.6 GO:0006703 estrogen biosynthetic process(GO:0006703)
4.4 8.7 GO:0072061 inner medullary collecting duct development(GO:0072061)
4.4 139.5 GO:0006749 glutathione metabolic process(GO:0006749)
4.3 8.7 GO:1904057 negative regulation of sensory perception of pain(GO:1904057)
4.3 30.4 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
4.3 34.7 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
4.3 8.7 GO:0007341 penetration of zona pellucida(GO:0007341)
4.3 8.6 GO:0072179 kidney rudiment formation(GO:0072003) nephric duct formation(GO:0072179) mesonephric duct formation(GO:0072181)
4.3 8.6 GO:0009445 putrescine metabolic process(GO:0009445)
4.3 21.6 GO:0000066 mitochondrial ornithine transport(GO:0000066)
4.3 34.4 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
4.3 8.6 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
4.3 4.3 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
4.3 8.6 GO:1904252 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
4.3 8.5 GO:0006114 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
4.3 12.8 GO:0055129 L-proline biosynthetic process(GO:0055129)
4.3 12.8 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
4.2 4.2 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
4.2 4.2 GO:0072525 pyridine-containing compound biosynthetic process(GO:0072525)
4.2 25.4 GO:0006657 CDP-choline pathway(GO:0006657)
4.2 37.8 GO:0090114 COPII-coated vesicle budding(GO:0090114)
4.2 16.7 GO:0006004 fucose metabolic process(GO:0006004)
4.2 191.7 GO:0008203 cholesterol metabolic process(GO:0008203)
4.2 12.5 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
4.2 4.2 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
4.2 16.6 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
4.1 12.4 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
4.1 20.7 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
4.1 8.3 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
4.1 12.4 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
4.1 12.4 GO:0090249 cell motility involved in somitogenic axis elongation(GO:0090247) regulation of cell motility involved in somitogenic axis elongation(GO:0090249)
4.1 20.5 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
4.1 12.3 GO:0070084 protein initiator methionine removal(GO:0070084)
4.1 20.3 GO:0035935 androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834)
4.0 16.1 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
4.0 8.0 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
4.0 16.0 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
4.0 8.0 GO:1990859 response to endothelin(GO:1990839) cellular response to endothelin(GO:1990859)
4.0 4.0 GO:0072053 renal inner medulla development(GO:0072053)
4.0 15.8 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
3.9 19.5 GO:0038007 netrin-activated signaling pathway(GO:0038007)
3.9 3.9 GO:0071217 cellular response to external biotic stimulus(GO:0071217)
3.9 7.8 GO:2000978 negative regulation of forebrain neuron differentiation(GO:2000978)
3.9 7.8 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
3.9 58.3 GO:0034587 piRNA metabolic process(GO:0034587)
3.9 19.4 GO:0038161 prolactin signaling pathway(GO:0038161)
3.9 11.6 GO:0019230 proprioception(GO:0019230)
3.9 3.9 GO:0032264 IMP salvage(GO:0032264)
3.8 134.5 GO:0007340 acrosome reaction(GO:0007340)
3.8 30.5 GO:0097327 response to antineoplastic agent(GO:0097327)
3.8 3.8 GO:0006311 meiotic gene conversion(GO:0006311) gene conversion(GO:0035822)
3.8 7.5 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
3.8 15.0 GO:0015793 glycerol transport(GO:0015793)
3.7 22.5 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
3.7 18.7 GO:0046881 positive regulation of follicle-stimulating hormone secretion(GO:0046881)
3.7 7.5 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
3.7 11.2 GO:0060816 random inactivation of X chromosome(GO:0060816) regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
3.7 3.7 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
3.7 51.8 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
3.7 22.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
3.7 18.4 GO:0061635 regulation of protein complex stability(GO:0061635)
3.7 66.1 GO:0045948 positive regulation of translational initiation(GO:0045948)
3.7 11.0 GO:0090367 negative regulation of mRNA modification(GO:0090367)
3.6 3.6 GO:0042668 auditory receptor cell fate determination(GO:0042668)
3.6 7.3 GO:0021698 cerebellar cortex structural organization(GO:0021698)
3.6 47.0 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
3.6 7.2 GO:0072221 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
3.6 25.1 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
3.6 17.9 GO:0016558 protein import into peroxisome matrix(GO:0016558)
3.6 10.7 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
3.6 10.7 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
3.6 17.8 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
3.6 3.6 GO:0099403 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
3.6 10.7 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
3.5 21.3 GO:0048859 formation of anatomical boundary(GO:0048859)
3.5 3.5 GO:0035106 operant conditioning(GO:0035106)
3.5 14.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
3.5 31.6 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
3.5 10.5 GO:0009301 snRNA transcription(GO:0009301)
3.5 3.5 GO:1904059 regulation of locomotor rhythm(GO:1904059)
3.5 14.0 GO:0030647 aminoglycoside antibiotic metabolic process(GO:0030647)
3.5 7.0 GO:0030210 heparin biosynthetic process(GO:0030210)
3.5 45.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
3.5 6.9 GO:0014735 regulation of muscle atrophy(GO:0014735)
3.5 6.9 GO:0009826 unidimensional cell growth(GO:0009826)
3.5 38.0 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
3.5 10.4 GO:0021764 amygdala development(GO:0021764)
3.4 6.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
3.4 20.6 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
3.4 17.0 GO:0007343 egg activation(GO:0007343)
3.4 10.2 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
3.4 13.5 GO:0097068 response to thyroxine(GO:0097068)
3.4 13.5 GO:0010587 miRNA catabolic process(GO:0010587)
3.4 6.8 GO:0061325 canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) cell proliferation involved in outflow tract morphogenesis(GO:0061325) receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963) regulation of cardiac ventricle development(GO:1904412)
3.4 30.4 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
3.4 30.2 GO:0070314 G1 to G0 transition(GO:0070314)
3.4 13.4 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
3.4 26.8 GO:0043482 endosome to melanosome transport(GO:0035646) pigment accumulation(GO:0043476) cellular pigment accumulation(GO:0043482) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
3.3 16.7 GO:0036016 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
3.3 6.6 GO:1904444 regulation of establishment of Sertoli cell barrier(GO:1904444)
3.3 13.2 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
3.3 3.3 GO:0060460 left lung development(GO:0060459) left lung morphogenesis(GO:0060460)
3.3 9.8 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
3.3 29.5 GO:0007028 cytoplasm organization(GO:0007028)
3.3 6.6 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
3.3 22.8 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
3.3 6.5 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
3.3 6.5 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
3.2 9.7 GO:0021524 visceral motor neuron differentiation(GO:0021524)
3.2 13.0 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
3.2 9.7 GO:2000682 positive regulation of rubidium ion transport(GO:2000682) positive regulation of rubidium ion transmembrane transporter activity(GO:2000688)
3.2 32.2 GO:0018298 protein-chromophore linkage(GO:0018298)
3.2 9.7 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
3.2 16.1 GO:0060179 male mating behavior(GO:0060179)
3.2 9.6 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
3.2 38.4 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
3.2 12.8 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
3.2 12.8 GO:0048669 collateral sprouting in absence of injury(GO:0048669)
3.2 9.5 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
3.2 12.7 GO:1901911 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
3.2 41.0 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
3.2 25.2 GO:0006068 ethanol catabolic process(GO:0006068) primary alcohol catabolic process(GO:0034310)
3.1 18.9 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
3.1 6.3 GO:0021603 cranial nerve formation(GO:0021603)
3.1 12.6 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
3.1 9.4 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
3.1 116.3 GO:0007032 endosome organization(GO:0007032)
3.1 72.3 GO:0007129 synapsis(GO:0007129)
3.1 22.0 GO:0035437 maintenance of protein localization in endoplasmic reticulum(GO:0035437)
3.1 34.5 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
3.1 6.3 GO:0031223 auditory behavior(GO:0031223)
3.1 18.8 GO:0072718 response to cisplatin(GO:0072718)
3.1 34.2 GO:0001967 suckling behavior(GO:0001967)
3.1 12.4 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
3.1 18.5 GO:0043587 tongue morphogenesis(GO:0043587)
3.1 9.2 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
3.1 9.2 GO:2000224 regulation of testosterone biosynthetic process(GO:2000224)
3.1 64.6 GO:0007130 synaptonemal complex assembly(GO:0007130)
3.1 18.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
3.1 27.5 GO:0072711 cellular response to hydroxyurea(GO:0072711)
3.1 24.5 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
3.1 12.2 GO:0006499 N-terminal protein myristoylation(GO:0006499)
3.0 21.3 GO:0060539 diaphragm development(GO:0060539)
3.0 6.1 GO:0005984 disaccharide metabolic process(GO:0005984)
3.0 9.0 GO:0071000 response to magnetism(GO:0071000)
3.0 3.0 GO:0010847 regulation of chromatin assembly(GO:0010847)
3.0 18.0 GO:0035095 behavioral response to nicotine(GO:0035095)
3.0 12.0 GO:0032849 regulation of cellular pH reduction(GO:0032847) positive regulation of cellular pH reduction(GO:0032849)
3.0 11.9 GO:0034398 telomere tethering at nuclear periphery(GO:0034398)
3.0 5.9 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
2.9 29.5 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
2.9 8.8 GO:0042374 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
2.9 8.7 GO:1903699 tarsal gland development(GO:1903699)
2.9 5.8 GO:1904045 cellular response to aldosterone(GO:1904045)
2.9 26.1 GO:0033762 response to glucagon(GO:0033762)
2.9 23.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
2.9 2.9 GO:0072709 cellular response to sorbitol(GO:0072709)
2.9 5.8 GO:2000437 regulation of monocyte extravasation(GO:2000437)
2.9 8.6 GO:1904823 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
2.9 20.0 GO:1901858 regulation of mitochondrial DNA metabolic process(GO:1901858)
2.9 22.9 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
2.8 17.0 GO:0018206 N-terminal peptidyl-methionine acetylation(GO:0017196) peptidyl-methionine modification(GO:0018206)
2.8 8.5 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
2.8 28.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
2.8 8.5 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
2.8 19.6 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
2.8 13.9 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
2.8 25.0 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
2.8 24.9 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
2.8 2.8 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
2.8 5.5 GO:1990478 response to ultrasound(GO:1990478)
2.8 8.3 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
2.7 27.3 GO:0009313 oligosaccharide catabolic process(GO:0009313)
2.7 30.0 GO:0003351 epithelial cilium movement(GO:0003351)
2.7 19.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
2.7 10.9 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
2.7 29.6 GO:0045056 transcytosis(GO:0045056)
2.7 8.0 GO:1902463 protein localization to cell leading edge(GO:1902463)
2.7 45.4 GO:0046460 neutral lipid biosynthetic process(GO:0046460) acylglycerol biosynthetic process(GO:0046463)
2.7 2.7 GO:0072289 renal vesicle induction(GO:0072034) ureter morphogenesis(GO:0072197) metanephric nephron tubule formation(GO:0072289)
2.7 13.3 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
2.7 8.0 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
2.6 18.5 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
2.6 5.3 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
2.6 28.9 GO:0000338 protein deneddylation(GO:0000338)
2.6 21.0 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
2.6 15.7 GO:0050957 equilibrioception(GO:0050957)
2.6 26.1 GO:0098902 regulation of membrane depolarization during action potential(GO:0098902)
2.6 5.2 GO:0035092 sperm chromatin condensation(GO:0035092)
2.6 15.6 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
2.6 43.7 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
2.6 25.7 GO:0034389 lipid particle organization(GO:0034389)
2.6 5.1 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
2.6 7.7 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
2.5 7.6 GO:0015766 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
2.5 17.8 GO:0070633 transepithelial transport(GO:0070633)
2.5 17.7 GO:0051549 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
2.5 35.4 GO:0009404 toxin metabolic process(GO:0009404)
2.5 15.0 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
2.5 19.9 GO:0032369 negative regulation of lipid transport(GO:0032369)
2.5 7.5 GO:1990166 protein localization to site of double-strand break(GO:1990166)
2.5 32.3 GO:0006517 protein deglycosylation(GO:0006517)
2.5 14.9 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
2.5 7.5 GO:1990168 protein K29-linked deubiquitination(GO:0035523) protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
2.5 7.4 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
2.5 117.8 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
2.4 26.9 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
2.4 9.8 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
2.4 21.9 GO:0042574 retinal metabolic process(GO:0042574)
2.4 21.7 GO:0046033 AMP metabolic process(GO:0046033)
2.4 7.2 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
2.4 2.4 GO:0051305 meiotic chromosome movement towards spindle pole(GO:0016344) chromosome movement towards spindle pole(GO:0051305)
2.4 4.8 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
2.4 9.6 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
2.4 21.5 GO:0051450 myoblast proliferation(GO:0051450)
2.4 7.1 GO:1901367 response to L-cysteine(GO:1901367)
2.4 7.1 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
2.3 9.3 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
2.3 18.6 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
2.3 30.2 GO:0033327 Leydig cell differentiation(GO:0033327)
2.3 13.9 GO:0006706 steroid catabolic process(GO:0006706)
2.3 36.8 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
2.3 6.9 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
2.3 6.8 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
2.3 77.6 GO:0031018 endocrine pancreas development(GO:0031018)
2.3 29.5 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
2.3 24.9 GO:0035268 protein mannosylation(GO:0035268)
2.3 4.5 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
2.2 13.5 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
2.2 8.9 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
2.2 13.4 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
2.2 4.5 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
2.2 8.9 GO:0019563 glycerol catabolic process(GO:0019563)
2.2 24.4 GO:0006465 signal peptide processing(GO:0006465)
2.2 2.2 GO:0060594 mammary gland specification(GO:0060594)
2.2 2.2 GO:0010635 regulation of mitochondrial fusion(GO:0010635)
2.2 48.3 GO:0002115 store-operated calcium entry(GO:0002115)
2.2 19.6 GO:0035608 protein deglutamylation(GO:0035608)
2.2 4.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
2.2 28.2 GO:0042407 cristae formation(GO:0042407)
2.2 4.3 GO:0001777 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
2.1 47.3 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
2.1 27.6 GO:0043248 proteasome assembly(GO:0043248)
2.1 4.2 GO:0071469 cellular response to alkaline pH(GO:0071469)
2.1 14.8 GO:0036159 inner dynein arm assembly(GO:0036159)
2.1 6.3 GO:0035036 sperm-egg recognition(GO:0035036)
2.1 27.4 GO:0015868 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
2.1 6.3 GO:0043654 recognition of apoptotic cell(GO:0043654)
2.1 12.6 GO:0060579 ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
2.1 12.5 GO:0032025 response to cobalt ion(GO:0032025)
2.1 6.2 GO:1902235 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902235)
2.1 47.6 GO:0045116 protein neddylation(GO:0045116)
2.1 10.4 GO:0048496 maintenance of organ identity(GO:0048496)
2.1 4.1 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
2.1 6.2 GO:0071529 cementum mineralization(GO:0071529)
2.1 55.8 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
2.1 8.2 GO:0006983 ER overload response(GO:0006983)
2.1 2.1 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
2.1 4.1 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
2.0 28.7 GO:0006783 heme biosynthetic process(GO:0006783)
2.0 10.2 GO:0042359 vitamin D metabolic process(GO:0042359)
2.0 4.1 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
2.0 2.0 GO:0040034 regulation of development, heterochronic(GO:0040034)
2.0 10.1 GO:0008292 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
2.0 10.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
2.0 14.2 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
2.0 10.1 GO:0015677 copper ion import(GO:0015677)
2.0 4.0 GO:0070193 synaptonemal complex organization(GO:0070193)
2.0 22.1 GO:0001886 endothelial cell morphogenesis(GO:0001886)
2.0 6.0 GO:0002525 acute inflammatory response to non-antigenic stimulus(GO:0002525)
2.0 2.0 GO:0045836 positive regulation of meiotic nuclear division(GO:0045836)
2.0 13.8 GO:0072717 cellular response to actinomycin D(GO:0072717)
2.0 3.9 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
1.9 11.7 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
1.9 13.6 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
1.9 13.5 GO:0070986 left/right axis specification(GO:0070986)
1.9 5.8 GO:0023021 termination of signal transduction(GO:0023021)
1.9 3.8 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) positive regulation of oocyte maturation(GO:1900195)
1.9 1.9 GO:0032762 mast cell cytokine production(GO:0032762)
1.9 5.7 GO:0031989 bombesin receptor signaling pathway(GO:0031989)
1.9 3.8 GO:0060751 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
1.9 9.4 GO:0071569 protein ufmylation(GO:0071569)
1.9 16.9 GO:0052697 xenobiotic glucuronidation(GO:0052697)
1.9 13.2 GO:0060710 chorio-allantoic fusion(GO:0060710)
1.9 22.5 GO:0021895 cerebral cortex neuron differentiation(GO:0021895)
1.9 3.8 GO:0045900 negative regulation of translational elongation(GO:0045900)
1.9 48.8 GO:0006879 cellular iron ion homeostasis(GO:0006879)
1.9 15.0 GO:0071468 cellular response to acidic pH(GO:0071468)
1.9 3.7 GO:0032900 negative regulation of neurotrophin production(GO:0032900)
1.9 11.2 GO:0021563 glossopharyngeal nerve development(GO:0021563)
1.9 5.6 GO:1902267 polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267)
1.8 7.4 GO:0034472 snRNA 3'-end processing(GO:0034472)
1.8 33.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
1.8 40.4 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
1.8 5.5 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
1.8 20.1 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
1.8 7.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
1.8 10.9 GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
1.8 5.4 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
1.8 10.8 GO:0035331 negative regulation of hippo signaling(GO:0035331)
1.8 5.4 GO:0042363 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) fat-soluble vitamin catabolic process(GO:0042363)
1.8 30.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
1.8 30.5 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
1.8 5.3 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
1.8 7.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
1.8 8.8 GO:0071472 cellular response to salt stress(GO:0071472)
1.8 7.0 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
1.8 5.3 GO:0071934 thiamine transmembrane transport(GO:0071934)
1.8 26.3 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
1.8 5.3 GO:0080154 regulation of fertilization(GO:0080154)
1.7 12.2 GO:0048840 otolith development(GO:0048840)
1.7 82.1 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418) tRNA aminoacylation(GO:0043039)
1.7 59.3 GO:0006505 GPI anchor metabolic process(GO:0006505)
1.7 1.7 GO:0007141 male meiosis I(GO:0007141)
1.7 109.6 GO:0030317 sperm motility(GO:0030317)
1.7 38.2 GO:0019373 epoxygenase P450 pathway(GO:0019373)
1.7 3.5 GO:0046477 glycosylceramide catabolic process(GO:0046477)
1.7 1.7 GO:0033564 anterior/posterior axon guidance(GO:0033564)
1.7 6.9 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
1.7 20.6 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
1.7 5.1 GO:0050955 thermoception(GO:0050955)
1.7 15.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
1.7 3.4 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
1.7 5.1 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
1.7 5.1 GO:1903225 integrin biosynthetic process(GO:0045112) negative regulation of endodermal cell differentiation(GO:1903225)
1.7 13.6 GO:0055059 asymmetric neuroblast division(GO:0055059)
1.7 3.4 GO:0035966 response to topologically incorrect protein(GO:0035966)
1.7 15.2 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
1.7 3.3 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
1.7 11.7 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
1.7 8.3 GO:0071294 cellular response to zinc ion(GO:0071294)
1.7 9.9 GO:2000035 regulation of stem cell division(GO:2000035)
1.7 3.3 GO:0016068 regulation of type I hypersensitivity(GO:0001810) type I hypersensitivity(GO:0016068)
1.6 11.5 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
1.6 18.1 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
1.6 11.5 GO:1903672 positive regulation of sprouting angiogenesis(GO:1903672)
1.6 14.8 GO:0048853 forebrain morphogenesis(GO:0048853)
1.6 29.4 GO:0006020 inositol metabolic process(GO:0006020)
1.6 4.9 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
1.6 4.9 GO:0060363 cranial suture morphogenesis(GO:0060363)
1.6 4.9 GO:1990403 embryonic brain development(GO:1990403)
1.6 4.8 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
1.6 1.6 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
1.6 8.0 GO:0010042 response to manganese ion(GO:0010042)
1.6 3.2 GO:0010998 regulation of translational initiation by eIF2 alpha phosphorylation(GO:0010998)
1.6 8.0 GO:0006699 bile acid biosynthetic process(GO:0006699)
1.6 12.8 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
1.6 23.9 GO:0035518 histone H2A monoubiquitination(GO:0035518)
1.6 4.8 GO:1903999 negative regulation of eating behavior(GO:1903999)
1.6 8.0 GO:0033034 positive regulation of neutrophil apoptotic process(GO:0033031) positive regulation of myeloid cell apoptotic process(GO:0033034)
1.6 4.8 GO:0032053 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
1.6 3.2 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
1.6 1.6 GO:1902915 protein poly-ADP-ribosylation(GO:0070212) negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
1.6 67.6 GO:0006414 translational elongation(GO:0006414)
1.6 3.1 GO:0036093 germ cell proliferation(GO:0036093)
1.6 7.8 GO:0014029 neural crest formation(GO:0014029)
1.6 34.3 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
1.5 1.5 GO:0044330 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330)
1.5 4.6 GO:1900060 negative regulation of sphingolipid biosynthetic process(GO:0090155) cellular sphingolipid homeostasis(GO:0090156) negative regulation of ceramide biosynthetic process(GO:1900060)
1.5 53.6 GO:0061077 chaperone-mediated protein folding(GO:0061077)
1.5 1.5 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
1.5 91.0 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
1.5 3.0 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
1.5 7.5 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
1.5 9.0 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
1.5 10.4 GO:0090161 Golgi ribbon formation(GO:0090161)
1.5 4.5 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
1.5 4.4 GO:0042976 activation of Janus kinase activity(GO:0042976)
1.5 13.2 GO:0007258 JUN phosphorylation(GO:0007258)
1.5 4.4 GO:0009597 detection of virus(GO:0009597)
1.5 7.3 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
1.5 11.7 GO:0044705 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
1.5 2.9 GO:0061009 common bile duct development(GO:0061009)
1.5 5.8 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
1.5 5.8 GO:0010992 ubiquitin homeostasis(GO:0010992)
1.4 52.2 GO:0032543 mitochondrial translation(GO:0032543)
1.4 7.2 GO:0035627 ceramide transport(GO:0035627)
1.4 15.9 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
1.4 4.3 GO:0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
1.4 10.1 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
1.4 2.9 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
1.4 7.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
1.4 8.5 GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394)
1.4 2.8 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128)
1.4 1.4 GO:0003415 chondrocyte hypertrophy(GO:0003415)
1.4 8.4 GO:0060177 regulation of angiotensin levels in blood(GO:0002002) regulation of angiotensin metabolic process(GO:0060177)
1.4 5.6 GO:0006544 glycine metabolic process(GO:0006544)
1.4 4.2 GO:0060536 cartilage morphogenesis(GO:0060536)
1.4 2.8 GO:0035376 sterol import(GO:0035376) cholesterol import(GO:0070508)
1.4 7.0 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
1.4 4.2 GO:1904178 sterol regulatory element binding protein import into nucleus(GO:0035105) negative regulation of adipose tissue development(GO:1904178)
1.4 37.7 GO:0002675 positive regulation of acute inflammatory response(GO:0002675)
1.4 5.6 GO:0046040 IMP metabolic process(GO:0046040)
1.4 7.0 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
1.4 5.6 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
1.4 6.9 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
1.4 12.5 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
1.4 11.1 GO:0001887 selenium compound metabolic process(GO:0001887)
1.4 4.1 GO:1902963 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
1.4 13.8 GO:2000169 regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
1.4 6.9 GO:0030432 peristalsis(GO:0030432)
1.4 4.1 GO:2000293 regulation of defecation(GO:2000292) negative regulation of defecation(GO:2000293)
1.4 6.9 GO:0015684 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
1.4 4.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
1.4 8.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
1.3 8.0 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
1.3 1.3 GO:0071387 cellular response to cortisol stimulus(GO:0071387)
1.3 30.5 GO:0006986 response to unfolded protein(GO:0006986)
1.3 35.2 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
1.3 5.2 GO:0060856 establishment of blood-brain barrier(GO:0060856)
1.3 5.2 GO:0015889 cobalamin transport(GO:0015889)
1.3 5.2 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
1.3 2.6 GO:0070861 regulation of protein exit from endoplasmic reticulum(GO:0070861) negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
1.3 3.9 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
1.3 20.4 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
1.3 3.8 GO:0008209 androgen metabolic process(GO:0008209)
1.3 10.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
1.3 3.8 GO:1902608 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
1.3 6.3 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
1.3 7.5 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
1.3 15.1 GO:1904030 negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
1.3 3.8 GO:0022900 electron transport chain(GO:0022900)
1.3 1.3 GO:0060702 negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702)
1.3 3.8 GO:0003263 cardioblast proliferation(GO:0003263) regulation of cardioblast proliferation(GO:0003264)
1.2 6.2 GO:0043586 tongue development(GO:0043586)
1.2 6.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
1.2 4.9 GO:0030576 Cajal body organization(GO:0030576)
1.2 2.5 GO:0046292 formaldehyde metabolic process(GO:0046292)
1.2 7.3 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
1.2 2.4 GO:0071362 cellular response to ether(GO:0071362) response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
1.2 4.9 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
1.2 3.6 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
1.2 8.5 GO:1901374 acetate ester transport(GO:1901374)
1.2 20.6 GO:0006098 pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
1.2 4.8 GO:0090151 establishment of protein localization to mitochondrial membrane(GO:0090151)
1.2 4.8 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
1.2 4.8 GO:0001555 oocyte growth(GO:0001555)
1.2 4.8 GO:0033523 histone H2B ubiquitination(GO:0033523)
1.2 7.2 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
1.2 16.8 GO:0016180 snRNA processing(GO:0016180)
1.2 2.4 GO:0035461 vitamin transmembrane transport(GO:0035461)
1.2 21.6 GO:0044458 motile cilium assembly(GO:0044458)
1.2 7.2 GO:0048102 autophagic cell death(GO:0048102)
1.2 8.3 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
1.2 7.1 GO:0001711 endodermal cell fate commitment(GO:0001711)
1.2 19.9 GO:0035987 endodermal cell differentiation(GO:0035987)
1.2 11.7 GO:0000920 cell separation after cytokinesis(GO:0000920)
1.2 16.3 GO:0070932 histone H3 deacetylation(GO:0070932)
1.2 2.3 GO:0016078 tRNA catabolic process(GO:0016078)
1.1 42.8 GO:0045454 cell redox homeostasis(GO:0045454)
1.1 5.6 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
1.1 10.1 GO:0048665 neuron fate specification(GO:0048665)
1.1 5.6 GO:0060484 lung-associated mesenchyme development(GO:0060484)
1.1 34.4 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
1.1 5.5 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
1.1 2.2 GO:0001543 ovarian follicle rupture(GO:0001543)
1.1 9.9 GO:0070327 thyroid hormone transport(GO:0070327)
1.1 14.3 GO:0098880 maintenance of postsynaptic specialization structure(GO:0098880) maintenance of postsynaptic density structure(GO:0099562)
1.1 1.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
1.1 4.4 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
1.1 2.2 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
1.1 7.6 GO:0046051 UTP metabolic process(GO:0046051)
1.1 10.8 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
1.1 2.2 GO:0046104 thymidine metabolic process(GO:0046104)
1.1 1.1 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
1.1 2.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
1.1 39.2 GO:0070830 bicellular tight junction assembly(GO:0070830)
1.1 6.3 GO:0070669 response to interleukin-2(GO:0070669)
1.0 16.8 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
1.0 8.4 GO:0016125 sterol metabolic process(GO:0016125)
1.0 5.2 GO:0060157 urinary bladder development(GO:0060157)
1.0 18.7 GO:0006694 steroid biosynthetic process(GO:0006694)
1.0 3.1 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
1.0 4.0 GO:0009115 xanthine catabolic process(GO:0009115)
1.0 9.0 GO:0042572 retinol metabolic process(GO:0042572)
1.0 320.6 GO:0007283 spermatogenesis(GO:0007283)
1.0 4.0 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
1.0 2.0 GO:1990009 retinal cell apoptotic process(GO:1990009)
1.0 1.9 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.9 12.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.9 3.8 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.9 26.3 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.9 9.3 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.9 14.7 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.9 7.3 GO:0009062 fatty acid catabolic process(GO:0009062)
0.9 4.6 GO:0015732 prostaglandin transport(GO:0015732)
0.9 1.8 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660)
0.9 1.8 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.9 1.8 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.9 10.8 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
0.9 1.8 GO:0071896 protein localization to adherens junction(GO:0071896)
0.9 2.7 GO:0048664 neuron fate determination(GO:0048664)
0.9 5.4 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.9 10.7 GO:0035584 calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.9 0.9 GO:0090009 primitive streak formation(GO:0090009)
0.9 18.3 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.9 5.2 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.9 35.4 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.9 2.6 GO:0016264 gap junction assembly(GO:0016264)
0.9 3.4 GO:0021984 adenohypophysis development(GO:0021984)
0.9 3.4 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.8 8.5 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.8 18.6 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.8 3.4 GO:0061709 reticulophagy(GO:0061709)
0.8 2.5 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.8 9.2 GO:0006312 mitotic recombination(GO:0006312)
0.8 3.3 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.8 10.7 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.8 7.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.8 6.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.8 9.0 GO:0033623 regulation of integrin activation(GO:0033623)
0.8 0.8 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.8 4.0 GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter(GO:0072364)
0.8 3.2 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902165) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.8 4.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.8 12.7 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.8 2.4 GO:0006563 L-serine metabolic process(GO:0006563)
0.8 7.8 GO:0019532 oxalate transport(GO:0019532)
0.8 23.4 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.8 10.1 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.8 1.6 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.8 4.7 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.8 2.3 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
0.8 8.5 GO:1900120 regulation of receptor binding(GO:1900120)
0.8 0.8 GO:0022615 protein to membrane docking(GO:0022615)
0.8 9.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.8 7.5 GO:0038092 nodal signaling pathway(GO:0038092)
0.8 5.3 GO:0015747 urate transport(GO:0015747)
0.7 0.7 GO:0051867 general adaptation syndrome, behavioral process(GO:0051867)
0.7 2.2 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.7 5.2 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.7 1.5 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.7 5.2 GO:0002911 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.7 2.2 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.7 5.1 GO:0060037 pharyngeal system development(GO:0060037)
0.7 11.4 GO:0001964 startle response(GO:0001964)
0.7 7.6 GO:0016574 histone ubiquitination(GO:0016574)
0.7 6.9 GO:0003417 growth plate cartilage development(GO:0003417)
0.7 2.7 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.7 5.4 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.7 12.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.7 2.0 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.7 1.3 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.7 3.4 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.7 2.7 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.7 5.3 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.7 11.2 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.7 2.0 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.7 0.7 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.7 4.0 GO:2000191 regulation of fatty acid transport(GO:2000191)
0.7 2.0 GO:0008206 bile acid metabolic process(GO:0008206)
0.7 0.7 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.6 3.9 GO:1904424 regulation of GTP binding(GO:1904424)
0.6 4.5 GO:0046415 urate metabolic process(GO:0046415)
0.6 1.9 GO:0038171 cannabinoid signaling pathway(GO:0038171)
0.6 1.3 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.6 0.6 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.6 1.9 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.6 1.9 GO:0045938 positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.6 18.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.6 0.6 GO:0019086 late viral transcription(GO:0019086)
0.6 22.2 GO:0051298 centrosome duplication(GO:0051298)
0.6 10.5 GO:0043648 dicarboxylic acid metabolic process(GO:0043648)
0.6 0.6 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.6 3.7 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.6 0.6 GO:0070471 uterine smooth muscle contraction(GO:0070471) regulation of uterine smooth muscle contraction(GO:0070472)
0.6 1.2 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.6 2.4 GO:0060178 regulation of exocyst localization(GO:0060178)
0.6 1.2 GO:0071895 odontoblast differentiation(GO:0071895)
0.6 5.8 GO:0071420 cellular response to histamine(GO:0071420)
0.6 1.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.6 1.7 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.6 7.9 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.6 1.1 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.6 9.0 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.6 11.7 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.6 14.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.6 2.2 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.5 18.5 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.5 5.4 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.5 1.6 GO:0051684 maintenance of Golgi location(GO:0051684)
0.5 5.9 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.5 2.2 GO:0048820 hair follicle maturation(GO:0048820)
0.5 1.1 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.5 2.7 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.5 1.6 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.5 0.5 GO:0009644 response to high light intensity(GO:0009644)
0.5 8.0 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.5 5.8 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.5 13.1 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.5 2.1 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.5 1.0 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.5 3.1 GO:0042446 hormone biosynthetic process(GO:0042446)
0.5 1.5 GO:0014739 positive regulation of muscle hyperplasia(GO:0014739)
0.5 9.7 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.5 2.0 GO:0001302 replicative cell aging(GO:0001302)
0.5 3.0 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.5 3.0 GO:0070166 enamel mineralization(GO:0070166)
0.5 1.5 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.5 8.0 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.5 4.0 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.5 6.8 GO:0060074 synapse maturation(GO:0060074)
0.5 9.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.5 5.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.5 2.9 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.5 5.3 GO:0042737 drug catabolic process(GO:0042737)
0.5 1.4 GO:0035878 nail development(GO:0035878)
0.5 5.6 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.5 2.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.5 1.8 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.5 1.4 GO:1904948 midbrain dopaminergic neuron differentiation(GO:1904948)
0.5 7.3 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.4 3.6 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.4 1.3 GO:0002158 osteoclast proliferation(GO:0002158)
0.4 1.8 GO:0010840 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.4 4.9 GO:0003341 cilium movement(GO:0003341)
0.4 5.7 GO:0060416 response to growth hormone(GO:0060416)
0.4 7.0 GO:0061512 protein localization to cilium(GO:0061512)
0.4 0.9 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.4 3.5 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.4 3.0 GO:0072348 sulfur compound transport(GO:0072348)
0.4 0.9 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.4 1.7 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.4 2.5 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.4 0.8 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.4 2.1 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.4 2.0 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.4 1.2 GO:0009750 response to fructose(GO:0009750)
0.4 1.2 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.4 6.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.4 5.3 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.4 1.6 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.4 2.0 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.4 0.8 GO:0060253 negative regulation of glial cell proliferation(GO:0060253)
0.4 0.8 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.4 2.7 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.4 1.1 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.4 0.4 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.4 1.9 GO:0032790 ribosome disassembly(GO:0032790)
0.4 22.5 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.4 1.1 GO:1901073 N-acetylglucosamine biosynthetic process(GO:0006045) N-acetylneuraminate biosynthetic process(GO:0046380) glucosamine-containing compound biosynthetic process(GO:1901073)
0.4 1.8 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.4 0.4 GO:0072202 cell differentiation involved in metanephros development(GO:0072202)
0.4 9.4 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.3 1.4 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.3 0.3 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.3 0.7 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.3 2.0 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.3 0.7 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.3 3.6 GO:0032836 glomerular basement membrane development(GO:0032836)
0.3 3.9 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.3 3.8 GO:0035137 hindlimb morphogenesis(GO:0035137)
0.3 0.6 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.3 0.3 GO:2000848 positive regulation of corticosteroid hormone secretion(GO:2000848)
0.3 1.2 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.3 6.7 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.3 29.2 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.3 6.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.3 3.8 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.3 6.2 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.3 1.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.3 2.0 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.3 2.0 GO:0031643 positive regulation of myelination(GO:0031643)
0.3 1.7 GO:0002192 cap-independent translational initiation(GO:0002190) IRES-dependent translational initiation(GO:0002192)
0.3 0.8 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.3 0.8 GO:0016240 autophagosome docking(GO:0016240)
0.3 0.8 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.3 1.4 GO:0002093 auditory receptor cell morphogenesis(GO:0002093)
0.3 1.4 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.3 1.3 GO:0089700 protein kinase D signaling(GO:0089700)
0.3 1.1 GO:0031507 heterochromatin assembly(GO:0031507)
0.3 1.8 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.3 3.8 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.3 1.3 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.3 2.3 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.2 1.0 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 10.0 GO:0006400 tRNA modification(GO:0006400)
0.2 13.0 GO:0016579 protein deubiquitination(GO:0016579)
0.2 1.3 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.2 0.4 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.2 1.7 GO:0032400 melanosome localization(GO:0032400)
0.2 2.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.2 7.0 GO:0060173 appendage development(GO:0048736) limb development(GO:0060173)
0.2 2.4 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.2 0.6 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.2 0.4 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.2 0.4 GO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
0.2 0.2 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.2 0.8 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.2 0.8 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.2 0.7 GO:0000212 meiotic spindle organization(GO:0000212)
0.1 0.7 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.1 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.1 0.9 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.1 1.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.3 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.1 2.5 GO:0098781 rRNA transcription(GO:0009303) ncRNA transcription(GO:0098781)
0.1 164.2 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 0.5 GO:0050917 sensory perception of umami taste(GO:0050917)
0.1 7.3 GO:0035308 negative regulation of protein dephosphorylation(GO:0035308)
0.1 0.6 GO:0023019 signal transduction involved in regulation of gene expression(GO:0023019)
0.1 0.2 GO:0036514 dopaminergic neuron axon guidance(GO:0036514) serotonergic neuron axon guidance(GO:0036515) planar cell polarity pathway involved in axon guidance(GO:1904938)
0.1 0.4 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 2.6 GO:0006112 energy reserve metabolic process(GO:0006112)
0.1 0.3 GO:0097502 mannosylation(GO:0097502)
0.1 2.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.4 GO:0072602 interleukin-4 secretion(GO:0072602)
0.1 0.6 GO:0042481 regulation of odontogenesis(GO:0042481)
0.1 0.2 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.1 4.1 GO:0045333 cellular respiration(GO:0045333)
0.1 0.8 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.1 0.1 GO:0001969 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
0.1 0.5 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1 0.1 GO:0034776 response to histamine(GO:0034776)
0.1 1.9 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.1 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.1 0.5 GO:0035743 CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745)
0.0 0.1 GO:0051030 snRNA transport(GO:0051030)
0.0 0.1 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.3 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.2 GO:0045616 regulation of keratinocyte differentiation(GO:0045616)
0.0 0.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.3 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.0 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.0 0.0 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.0 0.1 GO:0072575 hepatocyte proliferation(GO:0072574) epithelial cell proliferation involved in liver morphogenesis(GO:0072575)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
43.3 130.0 GO:0044317 rod spherule(GO:0044317)
24.4 146.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
22.7 68.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
21.7 65.1 GO:0000802 transverse filament(GO:0000802)
20.9 125.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
19.9 317.7 GO:0070852 cell body fiber(GO:0070852)
18.2 54.6 GO:0005960 glycine cleavage complex(GO:0005960)
18.2 236.1 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
17.8 89.2 GO:0070695 FHF complex(GO:0070695)
17.5 87.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
15.4 46.3 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
14.3 42.9 GO:0044316 cone cell pedicle(GO:0044316)
13.0 13.0 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
12.7 38.2 GO:0036488 CHOP-C/EBP complex(GO:0036488)
10.8 118.8 GO:0005915 zonula adherens(GO:0005915)
10.5 31.6 GO:0097543 ciliary inversin compartment(GO:0097543)
9.9 158.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
9.8 39.3 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
9.5 28.6 GO:0071942 XPC complex(GO:0071942)
9.3 27.8 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
9.2 27.6 GO:0055087 Ski complex(GO:0055087)
9.1 36.4 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
9.1 36.4 GO:0035363 histone locus body(GO:0035363)
8.9 187.9 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
8.7 52.4 GO:1990111 spermatoproteasome complex(GO:1990111)
8.6 42.8 GO:0070195 growth hormone receptor complex(GO:0070195)
8.5 42.5 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
8.4 50.6 GO:0097422 tubular endosome(GO:0097422)
8.4 33.6 GO:1990005 granular vesicle(GO:1990005)
8.4 25.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
8.3 24.9 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) fumarate reductase complex(GO:0045283)
8.2 8.2 GO:0031595 nuclear proteasome complex(GO:0031595)
8.1 56.6 GO:0070449 elongin complex(GO:0070449)
8.0 40.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
7.6 83.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
7.6 22.7 GO:0005956 protein kinase CK2 complex(GO:0005956)
7.5 37.7 GO:0048179 activin receptor complex(GO:0048179)
7.5 22.4 GO:1990429 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
7.3 43.7 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
7.2 21.7 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
7.2 21.5 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
7.0 147.5 GO:0001673 male germ cell nucleus(GO:0001673)
6.6 73.0 GO:0031010 ISWI-type complex(GO:0031010)
6.5 25.9 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
6.4 38.5 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
6.2 43.3 GO:0032300 mismatch repair complex(GO:0032300)
6.1 6.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
5.9 23.6 GO:0001405 presequence translocase-associated import motor(GO:0001405)
5.9 17.7 GO:0008537 proteasome activator complex(GO:0008537)
5.8 23.1 GO:0031417 NatC complex(GO:0031417)
5.7 17.0 GO:1990357 terminal web(GO:1990357)
5.7 22.7 GO:0072487 MSL complex(GO:0072487)
5.6 22.6 GO:0032280 symmetric synapse(GO:0032280)
5.6 22.4 GO:0061474 phagolysosome membrane(GO:0061474)
5.6 16.8 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
5.6 66.7 GO:0000801 central element(GO:0000801)
5.6 72.2 GO:0008385 IkappaB kinase complex(GO:0008385)
5.5 110.5 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
5.4 118.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
5.2 31.5 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
5.2 5.2 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
5.2 20.9 GO:0030121 AP-1 adaptor complex(GO:0030121)
5.2 135.7 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
5.2 15.6 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
5.1 36.0 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
5.1 36.0 GO:0016602 CCAAT-binding factor complex(GO:0016602)
5.1 5.1 GO:0045273 respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281)
5.1 86.3 GO:0035686 sperm fibrous sheath(GO:0035686)
5.0 5.0 GO:0060187 cell pole(GO:0060187)
4.9 53.8 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
4.8 24.0 GO:0030891 VCB complex(GO:0030891)
4.7 85.0 GO:0032433 filopodium tip(GO:0032433)
4.7 42.2 GO:0000138 Golgi trans cisterna(GO:0000138)
4.7 14.0 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
4.7 42.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
4.7 28.0 GO:0016461 unconventional myosin complex(GO:0016461)
4.6 32.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
4.5 49.7 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
4.5 35.9 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
4.3 13.0 GO:1990597 AIP1-IRE1 complex(GO:1990597)
4.2 101.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
4.2 611.2 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
4.2 37.4 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
4.0 35.9 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
3.9 19.5 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
3.8 26.9 GO:0097524 sperm plasma membrane(GO:0097524)
3.8 26.8 GO:0071203 WASH complex(GO:0071203)
3.7 48.7 GO:0000407 pre-autophagosomal structure(GO:0000407)
3.7 33.7 GO:0045179 apical cortex(GO:0045179)
3.7 55.9 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
3.7 14.9 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
3.7 7.4 GO:0030906 retromer, cargo-selective complex(GO:0030906)
3.7 44.0 GO:0032426 stereocilium tip(GO:0032426)
3.7 29.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
3.6 36.1 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
3.6 93.9 GO:0005640 nuclear outer membrane(GO:0005640)
3.6 21.5 GO:0005787 signal peptidase complex(GO:0005787)
3.5 1061.2 GO:0005759 mitochondrial matrix(GO:0005759)
3.5 10.6 GO:0005899 insulin receptor complex(GO:0005899)
3.5 21.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
3.5 21.2 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
3.5 31.4 GO:0098651 basement membrane collagen trimer(GO:0098651)
3.4 224.1 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
3.4 13.6 GO:0044301 climbing fiber(GO:0044301)
3.3 16.7 GO:0097452 GAIT complex(GO:0097452)
3.3 56.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
3.3 13.3 GO:0030478 actin cap(GO:0030478)
3.3 36.1 GO:0046581 intercellular canaliculus(GO:0046581)
3.2 9.7 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
3.2 22.4 GO:0061617 MICOS complex(GO:0061617)
3.2 419.8 GO:0001669 acrosomal vesicle(GO:0001669)
3.2 15.9 GO:0005785 signal recognition particle receptor complex(GO:0005785)
3.2 47.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
3.1 9.4 GO:0045098 type III intermediate filament(GO:0045098)
3.0 21.3 GO:0030991 intraciliary transport particle A(GO:0030991)
3.0 12.0 GO:0090543 Flemming body(GO:0090543)
3.0 11.8 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
3.0 11.8 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
2.8 58.2 GO:0005922 connexon complex(GO:0005922)
2.8 2.8 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
2.8 19.4 GO:0001739 sex chromatin(GO:0001739)
2.7 8.2 GO:0098830 presynaptic endosome(GO:0098830)
2.7 8.1 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
2.7 10.7 GO:0070876 SOSS complex(GO:0070876)
2.7 8.0 GO:0032807 DNA ligase IV complex(GO:0032807)
2.5 15.2 GO:0070847 core mediator complex(GO:0070847)
2.5 7.6 GO:0005745 m-AAA complex(GO:0005745)
2.5 10.0 GO:0061689 tricellular tight junction(GO:0061689)
2.5 15.0 GO:0030896 checkpoint clamp complex(GO:0030896)
2.5 12.3 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
2.4 2.4 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
2.4 9.7 GO:0005927 muscle tendon junction(GO:0005927)
2.4 127.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
2.4 21.6 GO:0070652 HAUS complex(GO:0070652)
2.3 72.6 GO:0035861 site of double-strand break(GO:0035861)
2.3 16.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
2.3 9.2 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
2.3 13.5 GO:0005672 transcription factor TFIIA complex(GO:0005672)
2.2 9.0 GO:0070765 gamma-secretase complex(GO:0070765)
2.2 11.0 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
2.2 99.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
2.2 43.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
2.1 12.8 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
2.1 4.3 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
2.1 10.5 GO:0097413 Lewy body(GO:0097413)
2.1 14.5 GO:0005827 polar microtubule(GO:0005827)
2.0 6.1 GO:0061574 ASAP complex(GO:0061574)
2.0 48.0 GO:0000795 synaptonemal complex(GO:0000795)
2.0 13.9 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
1.9 22.7 GO:0005832 chaperonin-containing T-complex(GO:0005832)
1.9 7.6 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
1.9 11.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
1.9 18.6 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
1.8 12.8 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
1.8 7.3 GO:0070578 RISC-loading complex(GO:0070578)
1.8 14.5 GO:0031209 SCAR complex(GO:0031209)
1.8 35.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
1.7 7.0 GO:0005879 axonemal microtubule(GO:0005879)
1.7 19.2 GO:0030008 TRAPP complex(GO:0030008)
1.7 3.5 GO:1990462 omegasome membrane(GO:1903349) omegasome(GO:1990462)
1.7 5.2 GO:0043564 Ku70:Ku80 complex(GO:0043564)
1.7 3.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
1.7 12.0 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
1.7 60.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
1.7 20.4 GO:0043202 lysosomal lumen(GO:0043202)
1.7 11.9 GO:0031415 NatA complex(GO:0031415)
1.7 13.6 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
1.7 5.1 GO:0034457 Mpp10 complex(GO:0034457)
1.7 166.4 GO:0072562 blood microparticle(GO:0072562)
1.7 11.7 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
1.7 11.6 GO:0016342 catenin complex(GO:0016342)
1.7 1.7 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
1.6 59.3 GO:1904115 axon cytoplasm(GO:1904115)
1.6 36.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
1.6 47.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
1.6 8.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
1.6 11.3 GO:1990909 Wnt signalosome(GO:1990909)
1.6 8.0 GO:0044194 cytolytic granule(GO:0044194)
1.6 19.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
1.6 3.2 GO:0034774 secretory granule lumen(GO:0034774)
1.6 11.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
1.6 106.2 GO:0031526 brush border membrane(GO:0031526)
1.5 59.8 GO:0005844 polysome(GO:0005844)
1.5 15.3 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
1.5 19.4 GO:0030126 COPI vesicle coat(GO:0030126)
1.5 16.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
1.5 8.9 GO:0005796 Golgi lumen(GO:0005796)
1.5 13.2 GO:0000813 ESCRT I complex(GO:0000813)
1.4 5.7 GO:0031597 cytosolic proteasome complex(GO:0031597)
1.4 8.6 GO:0033391 chromatoid body(GO:0033391)
1.4 2067.1 GO:0005739 mitochondrion(GO:0005739)
1.4 7.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
1.4 45.2 GO:0005801 cis-Golgi network(GO:0005801)
1.4 38.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
1.4 19.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
1.4 61.8 GO:0005637 nuclear inner membrane(GO:0005637)
1.3 699.8 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
1.3 28.2 GO:0032420 stereocilium(GO:0032420)
1.3 4.0 GO:0043511 inhibin complex(GO:0043511)
1.3 14.4 GO:0097539 ciliary transition fiber(GO:0097539)
1.3 2.5 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
1.3 31.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
1.3 16.3 GO:0035253 ciliary rootlet(GO:0035253)
1.2 24.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
1.2 12.1 GO:0072687 meiotic spindle(GO:0072687)
1.2 25.2 GO:0045120 pronucleus(GO:0045120)
1.2 13.1 GO:0030057 desmosome(GO:0030057)
1.2 20.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
1.2 11.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
1.1 7.8 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
1.1 8.8 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
1.1 4.4 GO:0005606 laminin-1 complex(GO:0005606)
1.0 5.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
1.0 40.1 GO:0043034 costamere(GO:0043034)
1.0 62.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
1.0 1.0 GO:0000137 Golgi cis cisterna(GO:0000137)
1.0 59.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
1.0 4.0 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
1.0 10.8 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
1.0 47.6 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
1.0 37.1 GO:0005811 lipid particle(GO:0005811)
0.9 3.8 GO:1990393 3M complex(GO:1990393)
0.9 8.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.9 2.8 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.9 13.0 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.9 2.7 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.9 8.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.9 8.0 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.9 4.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.9 1.7 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.9 1.7 GO:0034455 t-UTP complex(GO:0034455)
0.9 12.9 GO:0032039 integrator complex(GO:0032039)
0.8 40.4 GO:0005776 autophagosome(GO:0005776)
0.8 4.8 GO:0099571 postsynaptic actin cytoskeleton(GO:0098871) postsynaptic cytoskeleton(GO:0099571)
0.8 4.8 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.8 2.3 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.7 8.1 GO:0022624 proteasome accessory complex(GO:0022624)
0.7 1.5 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.7 3.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.7 6.6 GO:0035102 PRC1 complex(GO:0035102)
0.7 0.7 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.7 2.6 GO:0032021 NELF complex(GO:0032021)
0.6 1.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.6 1.8 GO:1990879 CST complex(GO:1990879)
0.6 6.8 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.6 5.5 GO:0005839 proteasome core complex(GO:0005839)
0.6 24.9 GO:0030667 secretory granule membrane(GO:0030667)
0.5 1.1 GO:0097165 nuclear stress granule(GO:0097165)
0.5 2.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.5 2.1 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.5 3.1 GO:0036396 MIS complex(GO:0036396)
0.5 1.5 GO:0071001 U4/U6 snRNP(GO:0071001)
0.5 6.1 GO:0005861 troponin complex(GO:0005861)
0.5 1.0 GO:0070939 Dsl1p complex(GO:0070939)
0.5 0.5 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.5 2.4 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.5 3.3 GO:0061700 GATOR2 complex(GO:0061700)
0.5 4.2 GO:0005845 mRNA cap binding complex(GO:0005845)
0.5 30.5 GO:0045095 keratin filament(GO:0045095)
0.4 2.5 GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177) proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.4 3.2 GO:0002177 manchette(GO:0002177)
0.3 1.4 GO:0018444 translation release factor complex(GO:0018444)
0.3 5.8 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.3 0.7 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.3 10.9 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.3 4.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 1.3 GO:0032584 growth cone membrane(GO:0032584)
0.3 1.8 GO:0000125 PCAF complex(GO:0000125)
0.3 3.5 GO:0032797 SMN complex(GO:0032797)
0.3 1.4 GO:0016272 prefoldin complex(GO:0016272)
0.3 1.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.3 0.8 GO:0044611 nuclear pore inner ring(GO:0044611)
0.3 2.2 GO:0000439 core TFIIH complex(GO:0000439)
0.3 1.9 GO:0033263 CORVET complex(GO:0033263)
0.3 2.3 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.2 2.5 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.2 0.5 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128)
0.2 2.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 8.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 0.6 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.2 2.0 GO:0017119 Golgi transport complex(GO:0017119)
0.2 1.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 1.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 0.5 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 2.1 GO:0000502 proteasome complex(GO:0000502)
0.1 2.0 GO:0001741 XY body(GO:0001741)
0.1 0.6 GO:0035859 Seh1-associated complex(GO:0035859)
0.1 0.4 GO:0036156 inner dynein arm(GO:0036156)
0.1 0.9 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.1 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 1.2 GO:0005882 intermediate filament(GO:0005882)
0.0 0.1 GO:0060091 kinocilium(GO:0060091)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.8 GO:0044291 cell-cell contact zone(GO:0044291)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
47.1 188.5 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
44.8 134.3 GO:0004370 glycerol kinase activity(GO:0004370)
44.6 223.2 GO:0004103 choline kinase activity(GO:0004103)
38.1 114.2 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
32.0 95.9 GO:0008405 arachidonic acid 11,12-epoxygenase activity(GO:0008405)
28.5 113.8 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
28.4 85.3 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
28.2 84.5 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
28.1 84.3 GO:0004359 glutaminase activity(GO:0004359)
27.1 135.4 GO:0034186 apolipoprotein A-I binding(GO:0034186)
26.1 78.2 GO:0004736 pyruvate carboxylase activity(GO:0004736)
25.7 77.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
25.1 75.3 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290)
25.1 100.3 GO:0003987 acetate-CoA ligase activity(GO:0003987)
25.0 75.0 GO:0008142 oxysterol binding(GO:0008142)
24.7 74.2 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
23.1 46.3 GO:0016841 ammonia-lyase activity(GO:0016841)
22.7 68.0 GO:0046911 metal chelating activity(GO:0046911)
21.4 85.4 GO:0004771 sterol esterase activity(GO:0004771)
21.2 169.5 GO:0008172 S-methyltransferase activity(GO:0008172)
20.2 40.3 GO:0015137 citrate transmembrane transporter activity(GO:0015137)
19.8 59.4 GO:0004655 porphobilinogen synthase activity(GO:0004655)
19.7 59.0 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
19.3 77.3 GO:0051870 methotrexate binding(GO:0051870)
18.8 37.5 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
18.7 56.0 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
18.1 54.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
17.5 70.1 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
17.1 51.3 GO:0000253 3-keto sterol reductase activity(GO:0000253)
16.6 49.9 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
16.5 49.6 GO:0032810 sterol response element binding(GO:0032810)
16.2 48.7 GO:0031752 D5 dopamine receptor binding(GO:0031752)
16.1 113.0 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
16.0 48.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
15.8 15.8 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
15.6 46.8 GO:0015203 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
15.5 31.0 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
15.2 75.8 GO:0070404 NADH binding(GO:0070404)
15.1 226.6 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
14.7 44.1 GO:0004522 ribonuclease A activity(GO:0004522)
14.6 43.9 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
14.5 43.5 GO:0008948 oxaloacetate decarboxylase activity(GO:0008948)
14.5 58.0 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
14.3 43.0 GO:2001070 starch binding(GO:2001070)
14.3 14.3 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
13.9 41.6 GO:0004657 proline dehydrogenase activity(GO:0004657)
13.4 120.4 GO:0008494 translation activator activity(GO:0008494)
13.1 52.3 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
13.0 91.0 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
12.5 49.9 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
12.4 49.4 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
12.1 36.4 GO:0045550 geranylgeranyl reductase activity(GO:0045550)
11.8 106.3 GO:0070402 NADPH binding(GO:0070402)
11.8 59.0 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
11.6 92.7 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
11.6 34.7 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
11.5 57.4 GO:0004301 epoxide hydrolase activity(GO:0004301)
11.4 297.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
11.2 56.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
11.0 99.0 GO:0019841 retinol binding(GO:0019841)
11.0 241.9 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
10.9 427.0 GO:0004364 glutathione transferase activity(GO:0004364)
10.9 32.8 GO:0004046 aminoacylase activity(GO:0004046)
10.7 53.6 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
10.7 42.8 GO:0004903 growth hormone receptor activity(GO:0004903)
10.7 63.9 GO:0005499 vitamin D binding(GO:0005499)
10.6 42.6 GO:0033149 FFAT motif binding(GO:0033149)
10.6 31.7 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
10.6 31.7 GO:0034057 RNA strand-exchange activity(GO:0034057)
10.5 115.7 GO:0039706 co-receptor binding(GO:0039706)
10.5 31.5 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
10.5 41.9 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
10.3 31.0 GO:0004807 triose-phosphate isomerase activity(GO:0004807)
10.1 80.8 GO:0051525 NFAT protein binding(GO:0051525)
10.0 90.1 GO:0005542 folic acid binding(GO:0005542)
9.9 29.7 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
9.9 29.6 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
9.7 38.9 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
9.7 19.4 GO:0032767 copper-dependent protein binding(GO:0032767)
9.4 28.2 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
9.4 37.5 GO:0004594 pantothenate kinase activity(GO:0004594)
9.3 18.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
9.2 27.5 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
9.0 35.9 GO:1904288 BAT3 complex binding(GO:1904288)
9.0 98.7 GO:0008242 omega peptidase activity(GO:0008242)
8.9 8.9 GO:0016151 nickel cation binding(GO:0016151)
8.7 26.2 GO:0043295 glutathione binding(GO:0043295)
8.7 61.0 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
8.5 8.5 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
8.4 25.3 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
8.4 42.2 GO:0035473 lipase binding(GO:0035473)
8.3 8.3 GO:0030284 estrogen receptor activity(GO:0030284)
8.3 24.9 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
8.3 49.8 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
8.2 41.1 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
8.2 24.5 GO:0004774 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775)
8.0 40.2 GO:0001155 TFIIIA-class transcription factor binding(GO:0001155)
8.0 64.2 GO:0015232 heme transporter activity(GO:0015232)
7.8 39.2 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
7.8 31.1 GO:0016842 amidine-lyase activity(GO:0016842)
7.8 31.1 GO:0061665 SUMO ligase activity(GO:0061665)
7.8 31.0 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
7.6 22.9 GO:0038100 nodal binding(GO:0038100)
7.5 29.9 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
7.5 22.4 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
7.4 22.3 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
7.4 22.3 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
7.4 29.6 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
7.4 22.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
7.4 58.8 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
7.3 29.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
7.2 72.4 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
7.2 21.5 GO:0042903 tubulin deacetylase activity(GO:0042903)
7.2 28.6 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
7.0 28.0 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
7.0 21.0 GO:0004335 galactokinase activity(GO:0004335)
7.0 34.9 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
7.0 34.9 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
6.9 62.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
6.9 27.6 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
6.8 27.4 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
6.6 32.9 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
6.6 65.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
6.5 58.3 GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679)
6.5 116.5 GO:0015643 toxic substance binding(GO:0015643)
6.4 19.2 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
6.4 31.9 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
6.3 139.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
6.2 6.2 GO:0038132 neuregulin binding(GO:0038132)
6.0 36.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
6.0 59.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
5.9 83.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
5.9 77.0 GO:0016881 acid-amino acid ligase activity(GO:0016881)
5.9 23.6 GO:0048408 epidermal growth factor binding(GO:0048408)
5.9 17.6 GO:0004040 amidase activity(GO:0004040)
5.8 40.8 GO:0034711 inhibin binding(GO:0034711)
5.8 23.3 GO:0047619 acylcarnitine hydrolase activity(GO:0047619)
5.8 69.7 GO:0016208 AMP binding(GO:0016208)
5.7 11.4 GO:0097677 STAT family protein binding(GO:0097677)
5.7 22.9 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
5.7 11.4 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
5.7 74.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
5.7 28.3 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
5.6 5.6 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
5.5 49.8 GO:0004017 adenylate kinase activity(GO:0004017)
5.5 11.1 GO:0098603 selenol Se-methyltransferase activity(GO:0098603)
5.5 215.3 GO:0070330 aromatase activity(GO:0070330)
5.5 16.5 GO:0070012 oligopeptidase activity(GO:0070012)
5.5 10.9 GO:0070698 type I activin receptor binding(GO:0070698)
5.5 27.3 GO:0004427 inorganic diphosphatase activity(GO:0004427)
5.3 21.3 GO:0004967 glucagon receptor activity(GO:0004967)
5.3 42.5 GO:0070053 thrombospondin receptor activity(GO:0070053)
5.3 21.2 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
5.3 15.9 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
5.3 26.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
5.2 15.7 GO:0005128 erythropoietin receptor binding(GO:0005128)
5.2 36.3 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
5.2 56.8 GO:0001972 retinoic acid binding(GO:0001972)
5.1 15.4 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
5.1 51.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
5.1 35.9 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
5.1 5.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
5.0 30.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
5.0 19.9 GO:0035727 lysophosphatidic acid binding(GO:0035727)
5.0 14.9 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
4.8 38.8 GO:0004311 farnesyltranstransferase activity(GO:0004311)
4.8 14.5 GO:0008396 oxysterol 7-alpha-hydroxylase activity(GO:0008396)
4.8 24.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
4.8 81.9 GO:0016854 racemase and epimerase activity(GO:0016854)
4.8 28.8 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
4.8 28.7 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
4.7 14.2 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
4.7 14.2 GO:0050294 steroid sulfotransferase activity(GO:0050294)
4.7 14.2 GO:0070905 serine binding(GO:0070905)
4.6 13.9 GO:0016833 oxo-acid-lyase activity(GO:0016833)
4.6 9.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
4.6 13.7 GO:0034618 arginine binding(GO:0034618)
4.6 22.8 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
4.5 94.4 GO:0015238 drug transmembrane transporter activity(GO:0015238)
4.5 22.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
4.5 13.4 GO:0004925 prolactin receptor activity(GO:0004925)
4.4 4.4 GO:0005135 interleukin-3 receptor binding(GO:0005135)
4.4 52.8 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
4.3 34.8 GO:0032184 SUMO polymer binding(GO:0032184)
4.3 43.3 GO:0070888 E-box binding(GO:0070888)
4.3 8.6 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
4.3 77.7 GO:0005537 mannose binding(GO:0005537)
4.3 17.3 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
4.3 12.9 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
4.3 17.2 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
4.3 25.7 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
4.3 17.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
4.2 42.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
4.2 33.6 GO:0004565 beta-galactosidase activity(GO:0004565)
4.2 25.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
4.2 4.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
4.2 46.0 GO:0051787 misfolded protein binding(GO:0051787)
4.2 25.0 GO:0001159 core promoter proximal region DNA binding(GO:0001159)
4.1 33.0 GO:0016885 ligase activity, forming carbon-carbon bonds(GO:0016885)
4.1 78.0 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
4.1 69.6 GO:0097602 cullin family protein binding(GO:0097602)
4.1 32.6 GO:0016405 CoA-ligase activity(GO:0016405)
4.1 40.6 GO:0042577 lipid phosphatase activity(GO:0042577)
4.1 89.2 GO:0003746 translation elongation factor activity(GO:0003746)
4.0 52.6 GO:0070628 proteasome binding(GO:0070628)
4.0 12.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
4.0 24.1 GO:0008420 CTD phosphatase activity(GO:0008420)
4.0 72.4 GO:0010181 FMN binding(GO:0010181)
4.0 28.1 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
4.0 20.0 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
3.9 19.6 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
3.9 11.8 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
3.9 19.5 GO:0005042 netrin receptor activity(GO:0005042)
3.9 23.4 GO:0042954 lipoprotein transporter activity(GO:0042954)
3.9 19.5 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
3.9 54.5 GO:0005243 gap junction channel activity(GO:0005243)
3.9 31.0 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
3.9 42.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
3.8 106.3 GO:0008198 ferrous iron binding(GO:0008198)
3.8 11.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
3.7 33.7 GO:0055102 lipase inhibitor activity(GO:0055102)
3.7 3.7 GO:0019238 cyclohydrolase activity(GO:0019238)
3.7 48.2 GO:0050321 tau-protein kinase activity(GO:0050321)
3.7 14.8 GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269)
3.7 22.0 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
3.7 11.0 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
3.6 43.5 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
3.6 125.6 GO:0045182 translation regulator activity(GO:0045182)
3.6 32.2 GO:0009881 photoreceptor activity(GO:0009881)
3.6 10.7 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
3.6 21.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
3.6 21.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
3.6 24.9 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
3.5 102.9 GO:0070064 proline-rich region binding(GO:0070064)
3.5 21.3 GO:0046870 cadmium ion binding(GO:0046870)
3.5 17.7 GO:0032557 pyrimidine ribonucleotide binding(GO:0032557)
3.5 3.5 GO:0032564 dATP binding(GO:0032564)
3.5 42.1 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
3.5 66.5 GO:0000030 mannosyltransferase activity(GO:0000030)
3.5 10.4 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
3.4 48.1 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
3.4 58.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
3.4 101.7 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
3.3 23.3 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
3.3 6.6 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
3.3 6.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
3.2 16.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
3.2 9.7 GO:0048039 ubiquinone binding(GO:0048039)
3.2 38.4 GO:0034185 apolipoprotein binding(GO:0034185)
3.2 31.9 GO:0051766 inositol trisphosphate kinase activity(GO:0051766)
3.2 12.7 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
3.2 82.1 GO:0019200 carbohydrate kinase activity(GO:0019200)
3.1 31.4 GO:0001846 opsonin binding(GO:0001846)
3.1 15.6 GO:0032027 myosin light chain binding(GO:0032027)
3.1 18.7 GO:0090599 alpha-glucosidase activity(GO:0090599)
3.1 15.6 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
3.1 140.2 GO:0019213 deacetylase activity(GO:0019213)
3.1 15.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
3.1 9.3 GO:0031208 POZ domain binding(GO:0031208)
3.1 89.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
3.0 3.0 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
3.0 20.7 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
2.9 2.9 GO:0019788 NEDD8 transferase activity(GO:0019788)
2.9 8.8 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
2.9 8.7 GO:0001069 regulatory region RNA binding(GO:0001069)
2.9 11.6 GO:0061133 endopeptidase activator activity(GO:0061133)
2.9 11.6 GO:0050682 AF-2 domain binding(GO:0050682)
2.9 14.4 GO:0071987 WD40-repeat domain binding(GO:0071987)
2.9 8.6 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
2.9 31.5 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
2.8 5.7 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
2.8 22.6 GO:0004035 alkaline phosphatase activity(GO:0004035)
2.8 14.1 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
2.8 11.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
2.8 11.1 GO:0015245 fatty acid transporter activity(GO:0015245)
2.8 13.9 GO:0046923 ER retention sequence binding(GO:0046923)
2.8 11.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
2.7 27.3 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
2.7 37.9 GO:0048018 receptor agonist activity(GO:0048018)
2.7 67.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
2.7 8.0 GO:0005534 galactose binding(GO:0005534)
2.7 80.1 GO:0042165 neurotransmitter binding(GO:0042165)
2.7 8.0 GO:0097603 temperature-gated ion channel activity(GO:0097603)
2.6 26.5 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
2.6 26.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
2.6 10.4 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
2.6 10.3 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
2.6 61.8 GO:0071837 HMG box domain binding(GO:0071837)
2.6 7.7 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
2.5 7.6 GO:0030984 kininogen binding(GO:0030984)
2.5 25.5 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
2.5 7.6 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
2.5 5.1 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
2.5 12.5 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
2.5 22.2 GO:0098879 structural constituent of postsynaptic specialization(GO:0098879) structural constituent of postsynaptic density(GO:0098919)
2.4 19.6 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
2.4 34.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
2.4 7.2 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
2.4 16.8 GO:0005173 stem cell factor receptor binding(GO:0005173)
2.4 7.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
2.4 28.6 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
2.4 11.9 GO:0097016 L27 domain binding(GO:0097016)
2.4 7.1 GO:0003921 GMP synthase activity(GO:0003921) GMP synthase (glutamine-hydrolyzing) activity(GO:0003922)
2.4 11.8 GO:0046790 virion binding(GO:0046790)
2.4 7.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
2.3 14.1 GO:0031014 troponin T binding(GO:0031014)
2.3 2.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
2.3 4.7 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
2.3 7.0 GO:0098821 BMP receptor activity(GO:0098821)
2.3 7.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)
2.3 34.6 GO:0045295 gamma-catenin binding(GO:0045295)
2.3 13.8 GO:0008395 steroid hydroxylase activity(GO:0008395)
2.3 16.0 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
2.3 4.5 GO:0030957 Tat protein binding(GO:0030957)
2.3 15.8 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
2.2 13.5 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
2.2 11.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
2.2 9.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
2.2 11.2 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
2.2 64.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
2.2 52.9 GO:0030332 cyclin binding(GO:0030332)
2.2 11.0 GO:0051920 peroxiredoxin activity(GO:0051920)
2.2 6.6 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
2.2 10.9 GO:0044390 ubiquitin-like protein conjugating enzyme binding(GO:0044390)
2.2 13.0 GO:0002151 G-quadruplex RNA binding(GO:0002151)
2.2 10.8 GO:0032052 bile acid binding(GO:0032052)
2.2 17.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
2.1 4.3 GO:0031177 phosphopantetheine binding(GO:0031177)
2.1 17.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
2.1 8.5 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
2.1 55.3 GO:0070001 aspartic-type peptidase activity(GO:0070001)
2.1 6.4 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
2.1 4.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
2.1 4.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
2.1 10.5 GO:0030348 syntaxin-3 binding(GO:0030348)
2.0 6.1 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
2.0 14.0 GO:0045503 dynein light chain binding(GO:0045503)
2.0 7.9 GO:0016149 translation release factor activity, codon specific(GO:0016149)
1.9 412.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
1.9 19.4 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
1.9 44.4 GO:0050661 NADP binding(GO:0050661)
1.9 38.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
1.9 5.7 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
1.9 5.7 GO:0004946 bombesin receptor activity(GO:0004946)
1.9 3.8 GO:0042134 rRNA primary transcript binding(GO:0042134)
1.9 29.9 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
1.9 20.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
1.9 9.3 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
1.8 20.2 GO:0070567 cytidylyltransferase activity(GO:0070567)
1.8 5.5 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
1.8 61.7 GO:0030506 ankyrin binding(GO:0030506)
1.8 21.7 GO:0004806 triglyceride lipase activity(GO:0004806)
1.8 10.7 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
1.7 14.0 GO:0001848 complement binding(GO:0001848)
1.7 7.0 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
1.7 10.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
1.7 13.8 GO:0030983 mismatched DNA binding(GO:0030983)
1.7 12.0 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832)
1.7 22.2 GO:0043522 leucine zipper domain binding(GO:0043522)
1.7 10.2 GO:0070410 co-SMAD binding(GO:0070410)
1.7 8.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
1.7 8.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
1.7 193.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
1.7 6.7 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
1.7 25.2 GO:0031418 L-ascorbic acid binding(GO:0031418)
1.7 80.1 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
1.7 9.9 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
1.7 44.6 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
1.6 32.9 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
1.6 9.8 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
1.6 11.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
1.6 103.4 GO:0005496 steroid binding(GO:0005496)
1.6 9.5 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
1.6 4.8 GO:0031893 vasopressin receptor binding(GO:0031893)
1.6 37.9 GO:0008308 voltage-gated anion channel activity(GO:0008308)
1.5 20.1 GO:0019789 SUMO transferase activity(GO:0019789)
1.5 10.8 GO:0045545 syndecan binding(GO:0045545)
1.5 6.1 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
1.5 19.8 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
1.5 6.0 GO:0019784 NEDD8-specific protease activity(GO:0019784)
1.5 4.5 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
1.5 1.5 GO:0042296 ISG15 transferase activity(GO:0042296)
1.5 26.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
1.5 11.8 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
1.5 19.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
1.5 22.0 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
1.5 33.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
1.4 5.7 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829)
1.4 14.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
1.4 2.8 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
1.4 4.2 GO:0004586 ornithine decarboxylase activity(GO:0004586)
1.4 2.8 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
1.4 9.8 GO:0016018 cyclosporin A binding(GO:0016018)
1.4 19.5 GO:0008199 ferric iron binding(GO:0008199)
1.4 5.6 GO:0035198 miRNA binding(GO:0035198)
1.4 8.3 GO:0070728 leucine binding(GO:0070728)
1.4 44.3 GO:0016836 hydro-lyase activity(GO:0016836)
1.4 17.9 GO:0001222 transcription corepressor binding(GO:0001222)
1.4 5.5 GO:0035614 snRNA stem-loop binding(GO:0035614)
1.4 19.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
1.4 12.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
1.4 17.6 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
1.3 9.4 GO:0070700 BMP receptor binding(GO:0070700)
1.3 9.4 GO:0004622 lysophospholipase activity(GO:0004622)
1.3 35.0 GO:0016831 carboxy-lyase activity(GO:0016831)
1.3 6.7 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
1.3 17.4 GO:0016289 CoA hydrolase activity(GO:0016289)
1.3 13.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
1.3 4.0 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
1.3 6.7 GO:0033265 choline binding(GO:0033265)
1.3 7.9 GO:0004659 prenyltransferase activity(GO:0004659)
1.3 9.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
1.3 22.2 GO:0008266 poly(U) RNA binding(GO:0008266)
1.3 38.8 GO:0051059 NF-kappaB binding(GO:0051059)
1.3 10.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
1.3 6.3 GO:0005550 pheromone binding(GO:0005550)
1.3 8.8 GO:0008061 chitin binding(GO:0008061)
1.3 20.2 GO:0000400 four-way junction DNA binding(GO:0000400)
1.2 40.5 GO:0008536 Ran GTPase binding(GO:0008536)
1.2 3.7 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
1.2 1.2 GO:0043559 insulin binding(GO:0043559)
1.2 4.9 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056) corticotropin-releasing hormone receptor activity(GO:0043404)
1.2 3.6 GO:0004064 arylesterase activity(GO:0004064)
1.2 2.4 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
1.2 14.4 GO:0004177 aminopeptidase activity(GO:0004177)
1.2 4.7 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
1.2 15.3 GO:0003993 acid phosphatase activity(GO:0003993)
1.2 2.3 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
1.2 1.2 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
1.1 17.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
1.1 9.1 GO:0043495 protein anchor(GO:0043495)
1.1 18.1 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
1.1 25.8 GO:0004623 phospholipase A2 activity(GO:0004623)
1.1 10.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
1.1 10.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
1.1 21.0 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
1.1 67.8 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
1.1 7.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
1.1 3.3 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
1.1 18.5 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
1.1 79.9 GO:0051082 unfolded protein binding(GO:0051082)
1.1 18.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
1.1 11.7 GO:0008131 primary amine oxidase activity(GO:0008131)
1.1 4.2 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
1.0 24.1 GO:0046966 thyroid hormone receptor binding(GO:0046966)
1.0 4.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
1.0 5.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
1.0 1.0 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
1.0 3.1 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
1.0 8.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
1.0 7.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
1.0 14.8 GO:0031996 thioesterase binding(GO:0031996)
1.0 4.8 GO:0004689 phosphorylase kinase activity(GO:0004689)
1.0 5.8 GO:0052744 phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.9 2.8 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.9 12.2 GO:0008483 transaminase activity(GO:0008483)
0.9 3.7 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.9 80.1 GO:0101005 ubiquitinyl hydrolase activity(GO:0101005)
0.9 8.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.9 5.5 GO:0042285 xylosyltransferase activity(GO:0042285)
0.9 12.9 GO:0070840 dynein complex binding(GO:0070840)
0.9 11.0 GO:0042056 chemoattractant activity(GO:0042056)
0.9 7.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.9 3.6 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.9 3.6 GO:0002046 opsin binding(GO:0002046)
0.9 4.5 GO:0071253 connexin binding(GO:0071253)
0.9 19.5 GO:0051287 NAD binding(GO:0051287)
0.9 3.5 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.9 22.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.9 5.2 GO:0031419 cobalamin binding(GO:0031419)
0.9 33.8 GO:0051213 dioxygenase activity(GO:0051213)
0.9 5.2 GO:0005047 signal recognition particle binding(GO:0005047)
0.9 8.6 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.9 21.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.8 3.4 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.8 5.9 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.8 3.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.8 3.3 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.8 17.2 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.8 3.2 GO:0001091 RNA polymerase II basal transcription factor binding(GO:0001091)
0.8 4.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.8 7.2 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.8 8.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.8 3.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.8 3.9 GO:0004985 opioid receptor activity(GO:0004985)
0.8 12.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.8 1.5 GO:0030621 U4 snRNA binding(GO:0030621)
0.8 30.1 GO:0030507 spectrin binding(GO:0030507)
0.8 16.9 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.8 2.3 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.7 3.0 GO:0034452 dynactin binding(GO:0034452)
0.7 11.9 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.7 9.6 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.7 16.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.7 1.5 GO:0035613 RNA stem-loop binding(GO:0035613)
0.7 8.0 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.7 5.8 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.7 5.8 GO:0016783 sulfurtransferase activity(GO:0016783)
0.7 23.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.7 3.6 GO:0051185 coenzyme transporter activity(GO:0051185)
0.7 2.2 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.7 9.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.7 10.3 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.7 114.4 GO:0017137 Rab GTPase binding(GO:0017137)
0.7 1.4 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.7 3.4 GO:0004977 melanocortin receptor activity(GO:0004977)
0.7 18.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.7 3.3 GO:0001007 transcription factor activity, RNA polymerase III transcription factor binding(GO:0001007)
0.6 8.4 GO:0003796 lysozyme activity(GO:0003796)
0.6 16.0 GO:0009975 cyclase activity(GO:0009975)
0.6 5.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.6 16.8 GO:0001221 transcription cofactor binding(GO:0001221)
0.6 97.9 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.6 4.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.6 3.5 GO:0071723 lipopeptide binding(GO:0071723)
0.6 1.8 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.6 8.1 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.6 2.3 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.6 2.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.6 2.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.6 8.0 GO:0033038 bitter taste receptor activity(GO:0033038)
0.6 1.7 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.6 4.0 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.6 7.4 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.6 2.3 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.6 1.7 GO:0030977 taurine binding(GO:0030977)
0.6 7.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.6 1.7 GO:0016748 succinyltransferase activity(GO:0016748)
0.5 6.0 GO:0070513 death domain binding(GO:0070513)
0.5 19.0 GO:0004620 phospholipase activity(GO:0004620)
0.5 6.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.5 1.5 GO:0001605 adrenomedullin receptor activity(GO:0001605)
0.5 1.5 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.5 8.5 GO:0001594 trace-amine receptor activity(GO:0001594)
0.5 4.0 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.5 3.4 GO:0004966 galanin receptor activity(GO:0004966)
0.5 3.9 GO:0008432 JUN kinase binding(GO:0008432)
0.5 6.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.5 17.1 GO:0004497 monooxygenase activity(GO:0004497)
0.5 14.6 GO:0099589 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.5 29.4 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.5 11.4 GO:0070491 repressing transcription factor binding(GO:0070491)
0.5 3.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.5 1.8 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.4 2.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.4 32.0 GO:0043130 ubiquitin binding(GO:0043130)
0.4 12.1 GO:0005109 frizzled binding(GO:0005109)
0.4 1.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.4 1.6 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.4 2.5 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.4 8.2 GO:0016896 3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.4 0.8 GO:0015616 DNA translocase activity(GO:0015616)
0.4 1.6 GO:0099528 G-protein coupled neurotransmitter receptor activity(GO:0099528)
0.4 16.4 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.4 1.9 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.4 1.9 GO:0030280 structural constituent of epidermis(GO:0030280)
0.4 3.4 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.4 15.7 GO:0035064 methylated histone binding(GO:0035064)
0.4 0.4 GO:0070883 pre-miRNA binding(GO:0070883)
0.4 5.5 GO:0031369 translation initiation factor binding(GO:0031369)
0.4 9.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.3 1.4 GO:0019776 Atg8 ligase activity(GO:0019776)
0.3 5.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.3 1.9 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.3 0.6 GO:0001635 calcitonin gene-related peptide receptor activity(GO:0001635)
0.3 42.7 GO:0005179 hormone activity(GO:0005179)
0.3 34.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.3 4.0 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.3 1.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.3 3.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.3 2.9 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.3 71.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.3 1.1 GO:0055100 adiponectin binding(GO:0055100)
0.3 0.8 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.3 3.5 GO:0043274 phospholipase binding(GO:0043274)
0.3 2.4 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.3 1.3 GO:0004974 leukotriene receptor activity(GO:0004974)
0.3 3.6 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.2 8.9 GO:0043022 ribosome binding(GO:0043022)
0.2 29.7 GO:0008168 methyltransferase activity(GO:0008168)
0.2 10.9 GO:0032947 protein complex scaffold(GO:0032947)
0.2 14.7 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.2 0.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.2 0.4 GO:0098918 structural constituent of synapse(GO:0098918)
0.2 1.3 GO:0005549 odorant binding(GO:0005549)
0.2 1.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.2 0.8 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.2 1.0 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2 60.9 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.2 2.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 1.5 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.1 156.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 4.0 GO:0038024 cargo receptor activity(GO:0038024)
0.1 0.3 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 35.3 GO:0019787 ubiquitin-like protein transferase activity(GO:0019787)
0.1 0.7 GO:0030275 LRR domain binding(GO:0030275)
0.1 0.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.5 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.2 GO:0000991 transcription factor activity, core RNA polymerase II binding(GO:0000991)
0.1 0.8 GO:0031491 nucleosome binding(GO:0031491)
0.1 0.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 1.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 7.4 GO:0003735 structural constituent of ribosome(GO:0003735)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
6.7 6.7 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
5.2 10.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
5.1 280.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
3.4 72.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
3.3 13.2 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
3.0 12.1 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
2.6 55.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
2.3 66.9 PID WNT SIGNALING PATHWAY Wnt signaling network
2.2 12.9 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
2.1 60.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
2.0 89.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
2.0 90.1 PID HNF3A PATHWAY FOXA1 transcription factor network
1.9 39.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
1.7 7.0 ST JAK STAT PATHWAY Jak-STAT Pathway
1.4 18.6 PID S1P S1P2 PATHWAY S1P2 pathway
1.4 35.4 PID ALK1 PATHWAY ALK1 signaling events
1.4 21.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
1.4 25.2 PID TRAIL PATHWAY TRAIL signaling pathway
1.4 48.7 PID AURORA A PATHWAY Aurora A signaling
1.4 36.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
1.4 27.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
1.3 8.0 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
1.3 34.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
1.3 67.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
1.2 9.6 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
1.2 25.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
1.1 55.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
1.1 5.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
1.1 19.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
1.1 7.5 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
1.0 24.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
1.0 12.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.9 9.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.7 22.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.7 45.4 PID E2F PATHWAY E2F transcription factor network
0.7 17.9 PID NETRIN PATHWAY Netrin-mediated signaling events
0.7 23.2 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.6 5.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.6 4.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.6 145.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.6 27.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.5 20.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.5 2.9 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.5 2.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.5 1.4 PID CD40 PATHWAY CD40/CD40L signaling
0.4 5.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.4 4.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.4 6.1 PID TNF PATHWAY TNF receptor signaling pathway
0.4 6.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.3 0.6 ST ADRENERGIC Adrenergic Pathway
0.3 3.9 PID FOXO PATHWAY FoxO family signaling
0.2 3.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 64.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.2 0.8 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.2 8.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.2 2.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 0.5 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 1.5 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.6 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.4 PID MTOR 4PATHWAY mTOR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
23.4 210.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
17.8 248.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
15.9 190.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
14.9 119.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
14.1 254.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
13.8 398.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
13.4 133.8 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
13.0 221.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
11.4 113.8 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
11.2 258.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
9.6 115.2 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
8.8 123.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
8.0 135.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
7.9 1038.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
7.9 94.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
7.6 22.7 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
7.5 89.8 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
6.9 137.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
6.8 88.8 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
6.8 6.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
6.4 173.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
6.1 103.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
5.7 68.0 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
5.5 219.0 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
5.0 5.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
4.9 9.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
4.9 4.9 REACTOME MITOTIC M M G1 PHASES Genes involved in Mitotic M-M/G1 phases
4.8 48.4 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
4.8 72.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
4.6 13.8 REACTOME XENOBIOTICS Genes involved in Xenobiotics
4.5 170.0 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
4.4 88.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
4.4 157.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
4.3 64.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
4.3 123.8 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
4.1 45.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
4.0 167.8 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
4.0 23.7 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
4.0 31.6 REACTOME OPSINS Genes involved in Opsins
3.8 72.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
3.8 41.8 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
3.7 59.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
3.6 50.6 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
3.5 38.6 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
3.5 24.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
3.4 37.0 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
3.3 52.7 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
3.3 78.1 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
3.1 55.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
3.1 30.9 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
3.1 43.0 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
3.1 45.9 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
2.8 56.8 REACTOME STEROID HORMONES Genes involved in Steroid hormones
2.8 39.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
2.8 108.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
2.8 57.9 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
2.7 30.2 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
2.5 53.4 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
2.5 53.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
2.5 5.1 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
2.5 47.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
2.5 27.5 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
2.5 32.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
2.5 14.9 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
2.5 81.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
2.5 36.8 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
2.4 2.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
2.4 50.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
2.4 2.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
2.3 32.6 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
2.3 18.4 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
2.3 22.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
2.2 22.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
2.2 28.6 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
2.2 10.8 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
2.2 86.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
2.1 58.9 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
2.1 43.6 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
2.1 24.9 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
2.0 22.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
1.9 25.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
1.9 16.8 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
1.9 77.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
1.8 43.6 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
1.8 41.1 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
1.8 5.4 REACTOME PKB MEDIATED EVENTS Genes involved in PKB-mediated events
1.6 19.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
1.6 6.5 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
1.6 28.9 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
1.6 62.2 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
1.5 95.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
1.5 11.8 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
1.5 88.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
1.5 18.9 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
1.5 2.9 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
1.4 45.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
1.4 8.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
1.4 10.9 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
1.4 10.9 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
1.3 4.0 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
1.3 18.2 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
1.3 16.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
1.2 53.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
1.2 4.9 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
1.2 16.9 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
1.2 86.7 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
1.2 9.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
1.2 3.5 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
1.1 11.2 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
1.1 15.6 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
1.1 36.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
1.0 164.5 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
1.0 15.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
1.0 2.9 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.9 45.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.9 2.8 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.8 2.5 REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES Genes involved in MAPK targets/ Nuclear events mediated by MAP kinases
0.8 42.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.8 17.1 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.8 21.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.7 6.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.7 8.7 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.7 12.9 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.7 12.1 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.7 12.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.6 13.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.6 2.5 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.6 19.1 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.6 2.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.6 6.8 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.5 13.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.4 12.6 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.4 7.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.3 2.0 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.3 6.6 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.3 3.8 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.2 6.1 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.2 4.6 REACTOME BIOLOGICAL OXIDATIONS Genes involved in Biological oxidations
0.2 1.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 3.4 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.2 0.6 REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS Genes involved in Acetylcholine Binding And Downstream Events
0.1 8.5 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.1 1.8 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 1.0 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.0 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex