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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Klf1

Z-value: 1.74

Motif logo

Transcription factors associated with Klf1

Gene Symbol Gene ID Gene Info
ENSRNOG00000003443 Kruppel like factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Klf1rn6_v1_chr19_+_26016382_260163820.357.3e-11Click!

Activity profile of Klf1 motif

Sorted Z-values of Klf1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_10417185 49.54 ENSRNOT00000082186
annexin A8
chr7_+_11077411 44.40 ENSRNOT00000007117
sphingosine-1-phosphate receptor 4
chr10_-_104628676 43.97 ENSRNOT00000010466
unc-13 homolog D
chr19_-_37427989 40.66 ENSRNOT00000022863
tubulin polymerization-promoting protein family member 3
chr10_-_56506446 36.18 ENSRNOT00000021357
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr1_-_142615673 34.33 ENSRNOT00000018021
IQ motif containing GTPase activating protein 1
chr4_-_100883038 33.62 ENSRNOT00000041880
thymosin, beta 10-like
chr4_-_100883275 31.83 ENSRNOT00000022846
thymosin, beta 10-like
chr13_+_89774764 31.79 ENSRNOT00000005619
Rho GTPase activating protein 30
chr6_-_1942972 31.60 ENSRNOT00000048711
CDC42 effector protein 3
chr14_+_91782354 30.06 ENSRNOT00000005902
IKAROS family zinc finger 1
chr7_+_94375020 29.30 ENSRNOT00000011904
nephroblastoma overexpressed
chr5_+_62840360 29.04 ENSRNOT00000088385
collagen type XV alpha 1 chain
chr13_+_27465930 28.72 ENSRNOT00000003314
serpin family B member 10
chr13_-_70626252 28.44 ENSRNOT00000036947
laminin subunit gamma 2
chr1_-_198128857 28.35 ENSRNOT00000026496
coronin 1A
chr1_+_80321585 28.01 ENSRNOT00000022895
creatine kinase, M-type
chr4_+_144382945 27.96 ENSRNOT00000007601
caveolin 3
chr3_+_14467330 26.83 ENSRNOT00000078939
gelsolin
chr8_+_44847157 26.65 ENSRNOT00000080288
CXADR-like membrane protein
chr3_-_177201525 26.26 ENSRNOT00000022451
regulator of G-protein signaling 19
chr7_-_70476340 25.98 ENSRNOT00000006800
Rho guanine nucleotide exchange factor 25
chr9_+_14529218 25.65 ENSRNOT00000016893
apolipoprotein B mRNA editing enzyme catalytic subunit 2
chr1_-_47331412 25.09 ENSRNOT00000046746
ezrin
chr1_-_145870912 24.06 ENSRNOT00000016289
interleukin 16
chr19_+_37235001 24.05 ENSRNOT00000020908
nucleolar protein 3
chr1_-_242765807 24.03 ENSRNOT00000020763
phosphoglucomutase 5
chrX_+_156463953 23.73 ENSRNOT00000079889
filamin A
chr4_+_100407658 23.59 ENSRNOT00000018562
capping actin protein, gelsolin like
chr20_-_5618254 23.49 ENSRNOT00000092326
ENSRNOT00000000576
BCL2-antagonist/killer 1
chr2_+_190007216 23.49 ENSRNOT00000015612
S100 calcium binding protein A6
chr5_+_151413382 23.18 ENSRNOT00000012626
CD164 molecule like 2
chr8_+_75687100 23.18 ENSRNOT00000038677
annexin A2
chr10_-_88036040 23.17 ENSRNOT00000018851
keratin 13
chr2_-_203680083 23.13 ENSRNOT00000021268
Cd2 molecule
chr1_+_1180932 22.67 ENSRNOT00000087443
retinoic acid early-inducible protein 1-gamma-like
chr16_-_36080191 22.39 ENSRNOT00000017635
high mobility group box 2-like 1
chr1_+_81230612 22.37 ENSRNOT00000026489
potassium calcium-activated channel subfamily N member 4
chr2_-_77632628 22.10 ENSRNOT00000073915
brain abundant, membrane attached signal protein 1
chr1_+_168964202 22.08 ENSRNOT00000089102
hemoglobin subunit beta-2-like
chr3_-_160730360 21.86 ENSRNOT00000075864
similar to secretory leukocyte protease inhibitor
chr20_-_3401273 21.64 ENSRNOT00000089257
ENSRNOT00000078451
ENSRNOT00000001085
nurim (nuclear envelope membrane protein)
chr10_+_48903540 21.55 ENSRNOT00000004248
transient receptor potential cation channel, subfamily V, member 2
chr1_-_81412251 21.20 ENSRNOT00000026946
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr3_-_160802433 21.04 ENSRNOT00000076191
secretory leukocyte peptidase inhibitor
chr1_-_89509343 20.94 ENSRNOT00000028637
FXYD domain-containing ion transport regulator 3
chr10_-_15590220 20.77 ENSRNOT00000048977
hemoglobin alpha, adult chain 2
chr10_+_94566928 20.50 ENSRNOT00000078446
proline rich 29
chr1_-_8751198 20.38 ENSRNOT00000030511
adhesion G protein-coupled receptor G6
chr19_-_37970537 20.28 ENSRNOT00000034722
dipeptidase 2
chr7_-_143837780 20.18 ENSRNOT00000016642
integrin subunit beta 7
chrX_+_65226748 20.11 ENSRNOT00000076181
moesin
chr4_+_117744075 19.86 ENSRNOT00000081173
adducin 2
chr1_+_168945449 19.86 ENSRNOT00000087661
ENSRNOT00000019913
hemoglobin subunit beta-2-like
chr17_+_9653561 19.84 ENSRNOT00000018899
PDZ and LIM domain 7
chr2_+_209766512 19.75 ENSRNOT00000092240
potassium voltage-gated channel subfamily A member 3
chr20_-_22004209 19.39 ENSRNOT00000086250
ENSRNOT00000068778
rhotekin 2
chr3_+_66193059 19.28 ENSRNOT00000006880
integrin subunit alpha 4
chr1_+_140602542 19.24 ENSRNOT00000085570
interferon stimulated exonuclease gene 20
chr13_-_52197205 19.17 ENSRNOT00000009712
shisa family member 4
chr14_-_100217913 19.10 ENSRNOT00000079167
pleckstrin
chr13_+_109713489 18.99 ENSRNOT00000004962
basic leucine zipper ATF-like transcription factor 3
chr5_+_157282669 18.98 ENSRNOT00000022827
phospholipase A2 group IIA
chr4_-_150244372 18.93 ENSRNOT00000047685
ret proto-oncogene
chr5_+_133865331 18.73 ENSRNOT00000035409
TAL bHLH transcription factor 1, erythroid differentiation factor
chr5_+_154522119 18.72 ENSRNOT00000072618
E2F transcription factor 2
chr15_-_33629699 18.48 ENSRNOT00000023302
myosin heavy chain 6
chr10_-_15305549 18.25 ENSRNOT00000027353
phosphatidylinositol glycan anchor biosynthesis, class Q
chr7_+_70364813 18.25 ENSRNOT00000084012
ENSRNOT00000031230
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr1_-_219532609 17.90 ENSRNOT00000025641
ankyrin repeat domain 13D
chr3_-_160739137 17.81 ENSRNOT00000075836
antileukoproteinase-like 2
chr3_-_160738927 17.74 ENSRNOT00000043470
antileukoproteinase-like 2
chr1_-_227441442 17.61 ENSRNOT00000028433
membrane spanning 4-domains A1
chr2_-_164634434 17.58 ENSRNOT00000018402
latexin
chr3_+_103726238 17.58 ENSRNOT00000006776
lysophosphatidylcholine acyltransferase 4
chr13_-_47979797 17.40 ENSRNOT00000080035
Ras association domain family member 5
chr6_-_138093643 17.37 ENSRNOT00000045874
immunoglobulin heavy chain 6
chr1_-_91074294 17.33 ENSRNOT00000075236
similar to Cytochrome c oxidase polypeptide VIIa-heart, mitochondrial precursor (Cytochrome c oxidase subunit VIIa-H) (COX VIIa-M)
chr3_+_119776925 17.32 ENSRNOT00000018549
dual specificity phosphatase 2
chr1_-_277181345 17.02 ENSRNOT00000038017
ENSRNOT00000038038
nebulin-related anchoring protein
chr1_-_168972725 16.93 ENSRNOT00000090422
hemoglobin subunit beta
chr4_-_14490446 16.90 ENSRNOT00000009132
semaphorin 3C
chr14_+_71649274 16.86 ENSRNOT00000004128
fibroblast growth factor binding protein 1
chrX_-_157013443 16.84 ENSRNOT00000082711
SRSF protein kinase 3
chr16_+_3851270 16.82 ENSRNOT00000014964
placenta-specific 9
chr8_+_59278262 16.72 ENSRNOT00000017053
DnaJ heat shock protein family (Hsp40) member A4
chr1_+_40529045 16.65 ENSRNOT00000026564
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr1_+_198528635 16.53 ENSRNOT00000022765
hypothetical protein LOC308990
chr6_+_137959171 16.52 ENSRNOT00000006835
cysteine rich protein 1
chr6_-_137733026 16.49 ENSRNOT00000019213
jagged 2
chr12_-_30566032 16.41 ENSRNOT00000093378
glioblastoma amplified sequence
chrX_-_38196060 16.31 ENSRNOT00000006741
ENSRNOT00000006438
SH3 domain-containing kinase-binding protein 1
chr7_-_121232741 16.30 ENSRNOT00000023196
platelet derived growth factor subunit B
chr1_-_101903910 16.21 ENSRNOT00000028656
epithelial membrane protein 3
chr1_+_89215266 16.17 ENSRNOT00000093612
ENSRNOT00000084799
dermokine
chr7_+_120153184 16.15 ENSRNOT00000013538
galectin 1
chr3_+_123731539 16.15 ENSRNOT00000051064
cell division cycle 25B
chr19_-_11669578 16.08 ENSRNOT00000026373
G protein subunit alpha o1
chr1_+_168957460 15.85 ENSRNOT00000090745
hemoglobin subunit beta-2
chr1_+_215610368 15.79 ENSRNOT00000078903
ENSRNOT00000087781
troponin I2, fast skeletal type
chr10_-_88874528 15.78 ENSRNOT00000026783
polymerase I and transcript release factor
chr14_+_37113210 15.74 ENSRNOT00000089094
sarcoglycan, beta
chr4_+_109467272 15.64 ENSRNOT00000008212
regenerating family member 3 beta
chr5_+_152681101 15.64 ENSRNOT00000076052
ENSRNOT00000022574
stathmin 1
chr3_+_11756384 15.62 ENSRNOT00000087762
SH2 domain containing 3C
chr19_-_27464805 15.62 ENSRNOT00000039467
origin recognition complex, subunit 6
chr13_-_47154292 15.61 ENSRNOT00000005284
CD55 molecule, decay accelerating factor for complement
chr13_-_70625842 15.25 ENSRNOT00000092499
laminin subunit gamma 2
chr1_-_81627710 15.21 ENSRNOT00000071704
CD177 antigen-like
chr2_+_193866951 15.20 ENSRNOT00000013393
S100 calcium binding protein A11
chr9_-_10757720 15.10 ENSRNOT00000083848
ubiquitin-like with PHD and ring finger domains 1
chr12_-_23624212 15.06 ENSRNOT00000064405
ENSRNOT00000001943
RAS p21 protein activator 4
chr5_-_58198782 14.81 ENSRNOT00000023951
C-C motif chemokine ligand 21
chr8_-_58647933 14.79 ENSRNOT00000038830
TNF alpha induced protein 8 like 3
chr15_-_29548400 14.77 ENSRNOT00000078176

chr3_+_111049315 14.70 ENSRNOT00000017223
serine peptidase inhibitor, Kunitz type 1
chr12_-_2438817 14.64 ENSRNOT00000037059
C-C motif chemokine ligand 25
chr9_+_16702460 14.56 ENSRNOT00000061432
protein tyrosine kinase 7
chr1_+_134699299 14.53 ENSRNOT00000068766
repulsive guidance molecule family member A
chr20_-_3605638 14.52 ENSRNOT00000074460
surfactant associated 2
chr10_-_40375605 14.48 ENSRNOT00000014464
annexin A6
chr6_-_139142218 14.30 ENSRNOT00000006975
Immunoglobulin heavy chain (gamma polypeptide)
chr1_-_89488223 14.24 ENSRNOT00000028624
FXYD domain-containing ion transport regulator 1
chr8_-_116391158 14.22 ENSRNOT00000078720
ENSRNOT00000022550
G protein subunit alpha i2
chr5_-_59025631 14.11 ENSRNOT00000049000
ENSRNOT00000022801
tropomyosin 2, beta
chr9_-_14668297 14.03 ENSRNOT00000042404
triggering receptor expressed on myeloid cells-like 2
chr16_-_81243757 14.02 ENSRNOT00000024677
growth arrest specific 6
chr4_+_117743710 13.90 ENSRNOT00000021491
adducin 2
chr5_-_152358643 13.88 ENSRNOT00000021734
SH3 domain binding glutamate-rich protein like 3
chr2_+_206064394 13.86 ENSRNOT00000077739
synaptotagmin 6
chr3_-_60105212 13.78 ENSRNOT00000086329
ENSRNOT00000025158
G protein-coupled receptor 155
chr5_-_151459037 13.74 ENSRNOT00000064472
ENSRNOT00000087836
synaptotagmin-like 1
chr10_+_89251370 13.74 ENSRNOT00000076820
amine oxidase, copper containing 3
chrX_-_32355296 13.69 ENSRNOT00000081652
ENSRNOT00000065075
adaptor-related protein complex 1, sigma 2 subunit
chr14_-_45165207 13.68 ENSRNOT00000002960
Kruppel like factor 3
chr16_+_2958283 13.67 ENSRNOT00000019511
Rho guanine nucleotide exchange factor 3
chr1_-_142183884 13.60 ENSRNOT00000016032
FES proto-oncogene, tyrosine kinase
chr1_+_39811314 13.56 ENSRNOT00000022046
protein phosphatase 1, regulatory (inhibitor) subunit 14c
chr19_+_26016382 13.29 ENSRNOT00000004601
Kruppel like factor 1
chr1_-_101236065 13.16 ENSRNOT00000066834
CD37 molecule
chr7_-_119797098 13.12 ENSRNOT00000009994
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr10_-_82785142 13.09 ENSRNOT00000005381
sarcoglycan, alpha
chr5_-_72287669 13.06 ENSRNOT00000022255
Kruppel like factor 4
chr1_+_215609645 13.02 ENSRNOT00000076140
ENSRNOT00000027487
troponin I2, fast skeletal type
chr16_+_8128689 13.01 ENSRNOT00000065618
polypeptide N-acetylgalactosaminyltransferase 15
chr18_-_11789697 12.94 ENSRNOT00000077304
ENSRNOT00000064554
desmocollin 3
chr16_-_64778486 12.92 ENSRNOT00000031701
ring finger protein 122
chr10_+_70262361 12.92 ENSRNOT00000064625
ENSRNOT00000076973
unc-45 myosin chaperone B
chr19_-_55490426 12.80 ENSRNOT00000081800
CBFA2/RUNX1 translocation partner 3
chr5_+_152533349 12.76 ENSRNOT00000067524
tripartite motif containing 63
chr8_+_11931767 12.74 ENSRNOT00000087963
mastermind-like transcriptional coactivator 2
chr20_-_4863011 12.65 ENSRNOT00000079503
lymphotoxin beta
chr19_+_37568113 12.65 ENSRNOT00000023710
family with sequence similarity 65, member A
chr2_+_95320283 12.62 ENSRNOT00000015537
hes-related family bHLH transcription factor with YRPW motif 1
chr9_+_9970209 12.56 ENSRNOT00000075215
DENN/MADD domain containing 1C
chr11_+_61083757 12.50 ENSRNOT00000002790
BOC cell adhesion associated, oncogene regulated
chr1_+_142087208 12.46 ENSRNOT00000017532
protein regulator of cytokinesis 1
chr1_+_29191192 12.30 ENSRNOT00000018718
hes-related family bHLH transcription factor with YRPW motif 2
chr10_-_14022452 12.28 ENSRNOT00000016554
neuropeptide W
chr10_-_4644570 12.20 ENSRNOT00000088279
stannin
chr1_+_226091774 12.20 ENSRNOT00000027693
fatty acid desaturase 3
chr8_+_99977334 12.19 ENSRNOT00000085808
ENSRNOT00000056704
ENSRNOT00000041859
procollagen lysine, 2-oxoglutarate 5-dioxygenase 2
chr8_-_50228369 12.16 ENSRNOT00000024030
transgelin
chr10_-_56962161 12.14 ENSRNOT00000026038
arachidonate 15-lipoxygenase
chrX_+_138046494 12.12 ENSRNOT00000010596
serine/threonine kinase 26
chr1_-_82610350 11.98 ENSRNOT00000028177
cytochrome P450, family 2, subfamily s, polypeptide 1
chr20_+_44521279 11.96 ENSRNOT00000085987
FYN proto-oncogene, Src family tyrosine kinase
chr6_+_132510757 11.95 ENSRNOT00000080230
Enah/Vasp-like
chr1_+_178351680 11.91 ENSRNOT00000018532
ENSRNOT00000076925
ENSRNOT00000076430
ENSRNOT00000076756
fatty acyl CoA reductase 1
chr1_-_84145916 11.84 ENSRNOT00000081796
latent transforming growth factor beta binding protein 4
chr4_+_78320190 11.70 ENSRNOT00000032742
ENSRNOT00000091359
GTPase, IMAP family member 4
chr5_+_169288871 11.69 ENSRNOT00000055466
TNF receptor superfamily member 25
chr10_-_15577977 11.67 ENSRNOT00000052292
hemoglobin alpha, adult chain 3
chr4_+_155321553 11.64 ENSRNOT00000089614
microfibrillar associated protein 5
chr19_-_55510460 11.61 ENSRNOT00000019820
CBFA2/RUNX1 translocation partner 3
chr19_+_24846938 11.60 ENSRNOT00000045974
DExD-box helicase 39A
chr1_+_105349069 11.60 ENSRNOT00000056030
neural EGFL like 1
chr8_+_5768811 11.57 ENSRNOT00000013936
matrix metallopeptidase 8
chr5_+_64476317 11.57 ENSRNOT00000017217
collagen alpha-1(XV) chain-like
chr17_-_68559471 11.55 ENSRNOT00000023252
phosphofructokinase, platelet
chr8_+_64481172 11.54 ENSRNOT00000015332
pyruvate kinase, muscle
chr4_+_99185885 11.53 ENSRNOT00000009392
CD8b molecule
chr9_+_37727942 11.53 ENSRNOT00000016511
ENSRNOT00000074276
myotilin-like
chr10_+_91254058 11.43 ENSRNOT00000087218
ENSRNOT00000065373
formin-like 1
chr1_+_31967978 11.30 ENSRNOT00000081471
ENSRNOT00000021532
thyroid hormone receptor interactor 13
chr6_-_142903440 11.28 ENSRNOT00000075707

chr1_-_220136470 11.24 ENSRNOT00000026812
actinin alpha 3
chr15_+_24153602 11.22 ENSRNOT00000014216
galectin 3
chr12_+_49761120 11.20 ENSRNOT00000070961
myosin XVIIIb
chr1_-_100669684 11.17 ENSRNOT00000091760
myosin heavy chain 14
chr4_+_168832910 11.14 ENSRNOT00000011134
G protein-coupled receptor, class C, group 5, member A
chr1_+_85386470 11.13 ENSRNOT00000093332
ENSRNOT00000044326
pleckstrin homology and RhoGEF domain containing G2
chr17_-_47394231 11.11 ENSRNOT00000079368
ENSRNOT00000079216
secreted frizzled-related protein 4
chr10_-_87067456 11.10 ENSRNOT00000014163
C-C motif chemokine receptor 7
chr20_+_5509059 11.09 ENSRNOT00000065349
kinesin family member C1
chr1_-_100671074 11.07 ENSRNOT00000027132
myosin heavy chain 14
chr7_-_118840634 11.04 ENSRNOT00000031568
apolipoprotein L 11a
chr15_+_110114148 10.97 ENSRNOT00000006264
integrin subunit beta like 1
chr1_-_7064870 10.97 ENSRNOT00000019983
syntaxin 11
chr8_+_116686601 10.95 ENSRNOT00000066104
macrophage stimulating 1 receptor

Network of associatons between targets according to the STRING database.

First level regulatory network of Klf1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
14.7 44.0 GO:0002432 granuloma formation(GO:0002432)
9.8 29.3 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392) negative regulation of sensory perception of pain(GO:1904057)
9.7 29.1 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)
9.6 38.6 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
8.3 24.9 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
8.0 24.1 GO:0014736 negative regulation of muscle atrophy(GO:0014736)
7.7 23.2 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
7.7 23.2 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
7.5 45.2 GO:1902966 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
7.5 30.1 GO:0045658 regulation of neutrophil differentiation(GO:0045658)
7.1 42.5 GO:1904995 negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
7.1 49.5 GO:0032429 regulation of phospholipase A2 activity(GO:0032429)
7.0 105.0 GO:0015671 oxygen transport(GO:0015671)
7.0 28.0 GO:0035995 detection of muscle stretch(GO:0035995) positive regulation of caveolin-mediated endocytosis(GO:2001288)
6.9 34.3 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
6.6 13.2 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
6.5 26.1 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
6.4 19.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
6.4 25.6 GO:0016554 cytidine to uridine editing(GO:0016554)
6.3 12.6 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
6.2 18.5 GO:1905242 response to 3,3',5-triiodo-L-thyronine(GO:1905242) cellular response to 3,3',5-triiodo-L-thyronine(GO:1905243)
6.2 6.2 GO:0035993 deltoid tuberosity development(GO:0035993)
6.1 30.3 GO:0003104 positive regulation of glomerular filtration(GO:0003104)
5.6 16.7 GO:0015942 formate metabolic process(GO:0015942)
5.0 19.9 GO:0070560 protein secretion by platelet(GO:0070560)
4.8 19.3 GO:0050904 diapedesis(GO:0050904)
4.8 14.3 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788)
4.7 23.7 GO:1905031 regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905031)
4.7 4.7 GO:2000564 regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
4.5 27.0 GO:0048597 B cell selection(GO:0002339) post-embryonic camera-type eye morphogenesis(GO:0048597)
4.5 22.3 GO:2000520 regulation of immunological synapse formation(GO:2000520)
4.4 17.5 GO:1903575 cornified envelope assembly(GO:1903575)
4.4 39.3 GO:0043320 natural killer cell degranulation(GO:0043320)
4.3 17.4 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
4.3 21.5 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
4.3 34.2 GO:0010216 maintenance of DNA methylation(GO:0010216)
4.2 16.9 GO:0003350 pulmonary myocardium development(GO:0003350)
4.2 12.7 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
4.1 12.2 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
4.0 48.5 GO:0045820 negative regulation of glycolytic process(GO:0045820)
3.9 15.6 GO:1903576 response to L-arginine(GO:1903576)
3.8 11.4 GO:0002488 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
3.8 22.8 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
3.6 14.2 GO:1903797 positive regulation of inorganic anion transmembrane transport(GO:1903797)
3.5 17.6 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
3.4 10.3 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
3.4 20.6 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
3.4 6.7 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
3.4 43.7 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
3.3 13.2 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
3.3 16.5 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
3.3 65.6 GO:0070831 basement membrane assembly(GO:0070831)
3.3 9.8 GO:0046103 inosine biosynthetic process(GO:0046103)
3.2 9.7 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103)
3.2 16.2 GO:0002317 plasma cell differentiation(GO:0002317)
3.2 9.7 GO:0021678 third ventricle development(GO:0021678)
3.2 12.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
3.0 9.1 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
3.0 9.0 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
3.0 24.0 GO:0019388 galactose catabolic process(GO:0019388)
2.9 8.8 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
2.9 8.6 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
2.9 31.6 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
2.9 31.4 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
2.8 11.4 GO:0097084 vascular smooth muscle cell development(GO:0097084)
2.8 14.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
2.8 25.4 GO:0043587 tongue morphogenesis(GO:0043587)
2.8 8.5 GO:0043474 eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) rhodopsin metabolic process(GO:0046154)
2.8 16.9 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
2.8 5.5 GO:0030221 basophil differentiation(GO:0030221)
2.8 13.9 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
2.7 60.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
2.7 8.2 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
2.7 21.7 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
2.7 5.3 GO:0032423 regulation of mismatch repair(GO:0032423)
2.7 8.0 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
2.6 5.2 GO:0070268 cornification(GO:0070268)
2.6 7.7 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
2.6 23.1 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
2.5 7.6 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
2.5 7.5 GO:0021815 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
2.5 24.6 GO:0050930 induction of positive chemotaxis(GO:0050930)
2.4 7.2 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
2.4 28.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
2.4 14.3 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
2.4 9.5 GO:0034436 glycoprotein transport(GO:0034436)
2.4 7.1 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
2.4 11.8 GO:1904717 regulation of AMPA glutamate receptor clustering(GO:1904717)
2.3 4.7 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
2.3 2.3 GO:1903796 negative regulation of inorganic anion transmembrane transport(GO:1903796)
2.3 9.0 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
2.2 11.0 GO:0010032 meiotic chromosome condensation(GO:0010032)
2.2 2.2 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
2.2 13.1 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
2.2 6.5 GO:0051012 microtubule sliding(GO:0051012)
2.2 6.5 GO:1901558 response to metformin(GO:1901558) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
2.2 6.5 GO:2001106 fasciculation of motor neuron axon(GO:0097156) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
2.2 6.5 GO:0016476 regulation of embryonic cell shape(GO:0016476)
2.2 6.5 GO:0010265 SCF complex assembly(GO:0010265)
2.1 34.3 GO:0014870 response to muscle inactivity(GO:0014870)
2.1 10.5 GO:0060486 Clara cell differentiation(GO:0060486)
2.1 6.3 GO:2001205 negative regulation of osteoclast development(GO:2001205)
2.1 6.3 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
2.1 8.3 GO:0072244 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
2.1 8.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
2.1 16.5 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
2.1 6.2 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
2.0 4.0 GO:1905007 positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905007)
2.0 6.0 GO:2000660 negative regulation of chemokine biosynthetic process(GO:0045079) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
2.0 10.0 GO:2000327 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
2.0 13.9 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
2.0 11.9 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
2.0 23.7 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
2.0 5.9 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
1.9 5.8 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
1.9 5.8 GO:0072237 metanephric proximal tubule development(GO:0072237)
1.9 9.6 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
1.9 13.4 GO:0007144 female meiosis I(GO:0007144)
1.9 9.5 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
1.9 9.5 GO:0080154 regulation of fertilization(GO:0080154)
1.9 11.2 GO:0051014 actin filament severing(GO:0051014)
1.9 22.4 GO:0006265 DNA topological change(GO:0006265)
1.9 13.0 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
1.8 7.3 GO:0042339 keratan sulfate metabolic process(GO:0042339)
1.8 5.5 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
1.8 9.0 GO:1900194 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
1.8 7.2 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
1.8 5.3 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
1.8 5.3 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
1.7 3.5 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
1.7 31.2 GO:0070571 negative regulation of neuron projection regeneration(GO:0070571)
1.7 6.8 GO:0033277 abortive mitotic cell cycle(GO:0033277)
1.7 5.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
1.7 5.1 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
1.7 3.4 GO:1900195 positive regulation of oocyte maturation(GO:1900195)
1.7 8.3 GO:0090131 mesenchyme migration(GO:0090131)
1.6 9.8 GO:0090166 Golgi disassembly(GO:0090166)
1.6 6.5 GO:0006272 leading strand elongation(GO:0006272)
1.6 6.5 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
1.6 8.1 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
1.6 4.9 GO:0033566 gamma-tubulin complex localization(GO:0033566)
1.6 11.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
1.6 11.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
1.6 4.8 GO:0060594 mammary gland specification(GO:0060594)
1.6 4.8 GO:0060279 positive regulation of ovulation(GO:0060279)
1.6 20.5 GO:0006527 arginine catabolic process(GO:0006527)
1.6 9.4 GO:0002457 T cell antigen processing and presentation(GO:0002457)
1.6 6.2 GO:0072014 proximal tubule development(GO:0072014)
1.5 7.7 GO:2000173 negative regulation of branching morphogenesis of a nerve(GO:2000173)
1.5 9.2 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
1.5 30.3 GO:0006924 activation-induced cell death of T cells(GO:0006924)
1.5 13.6 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
1.5 4.4 GO:1902412 positive regulation of centriole replication(GO:0046601) regulation of mitotic cytokinesis(GO:1902412)
1.5 8.9 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
1.4 13.0 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
1.4 15.9 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
1.4 4.3 GO:0090669 telomerase RNA stabilization(GO:0090669)
1.4 7.2 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
1.4 7.1 GO:0051136 regulation of NK T cell differentiation(GO:0051136)
1.4 4.3 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344) regulation of bleb assembly(GO:1904170)
1.4 14.2 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
1.4 2.8 GO:1900114 positive regulation of histone H3-K9 trimethylation(GO:1900114)
1.4 5.6 GO:0098886 modification of dendritic spine(GO:0098886)
1.4 4.2 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
1.4 16.6 GO:0030913 paranodal junction assembly(GO:0030913)
1.4 12.4 GO:0043249 erythrocyte maturation(GO:0043249)
1.4 24.7 GO:0032816 positive regulation of natural killer cell activation(GO:0032816)
1.4 8.2 GO:0046208 spermine catabolic process(GO:0046208)
1.4 2.7 GO:0030186 melatonin metabolic process(GO:0030186)
1.4 2.7 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
1.4 8.1 GO:0021633 optic nerve structural organization(GO:0021633)
1.4 8.1 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
1.3 9.4 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
1.3 8.1 GO:0001866 NK T cell proliferation(GO:0001866)
1.3 9.4 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
1.3 14.6 GO:0060484 lung-associated mesenchyme development(GO:0060484)
1.3 5.2 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
1.3 1.3 GO:0021997 neural plate axis specification(GO:0021997)
1.3 1.3 GO:0003415 chondrocyte hypertrophy(GO:0003415)
1.3 5.1 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
1.3 10.1 GO:0060297 regulation of sarcomere organization(GO:0060297)
1.3 8.8 GO:0071681 cellular response to indole-3-methanol(GO:0071681)
1.3 3.8 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
1.2 7.4 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
1.2 17.3 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
1.2 8.6 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
1.2 3.7 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
1.2 1.2 GO:1902488 cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
1.2 6.0 GO:0033623 regulation of integrin activation(GO:0033623)
1.2 7.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
1.2 5.9 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
1.2 4.7 GO:0070459 prolactin secretion(GO:0070459)
1.2 5.9 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
1.2 23.4 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
1.2 5.8 GO:1903333 negative regulation of protein folding(GO:1903333)
1.2 4.7 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
1.2 5.8 GO:0035617 stress granule disassembly(GO:0035617)
1.2 8.1 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
1.1 5.7 GO:0031657 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
1.1 13.7 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
1.1 5.7 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
1.1 3.4 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512) regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling(GO:0060683) embryonic lung development(GO:1990401)
1.1 3.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
1.1 11.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
1.1 3.4 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
1.1 6.7 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
1.1 5.5 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
1.1 7.7 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
1.1 31.8 GO:0006270 DNA replication initiation(GO:0006270)
1.1 45.8 GO:0003009 skeletal muscle contraction(GO:0003009)
1.1 12.0 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
1.1 4.3 GO:1900224 zygotic specification of dorsal/ventral axis(GO:0007352) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
1.1 18.1 GO:0031581 hemidesmosome assembly(GO:0031581)
1.1 4.2 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
1.1 2.1 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
1.0 3.1 GO:0018201 peptidyl-glycine modification(GO:0018201)
1.0 24.0 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
1.0 3.1 GO:0060383 positive regulation of DNA strand elongation(GO:0060383)
1.0 6.2 GO:0071918 urea transmembrane transport(GO:0071918)
1.0 2.1 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
1.0 2.1 GO:1903406 regulation of sodium:potassium-exchanging ATPase activity(GO:1903406)
1.0 10.4 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
1.0 11.4 GO:0086027 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
1.0 17.6 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
1.0 6.2 GO:1990253 cellular response to leucine starvation(GO:1990253)
1.0 3.1 GO:0032472 Golgi calcium ion transport(GO:0032472)
1.0 3.0 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
1.0 3.0 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
1.0 4.0 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
1.0 8.0 GO:0006751 glutathione catabolic process(GO:0006751)
1.0 7.0 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
1.0 15.7 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
1.0 9.6 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
1.0 2.9 GO:0015820 leucine transport(GO:0015820)
0.9 3.8 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.9 8.5 GO:0002467 germinal center formation(GO:0002467)
0.9 22.5 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.9 2.8 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.9 0.9 GO:0060018 astrocyte fate commitment(GO:0060018)
0.9 13.9 GO:0032060 bleb assembly(GO:0032060)
0.9 4.6 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.9 1.8 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.9 4.6 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.9 4.5 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.9 11.7 GO:0017121 phospholipid scrambling(GO:0017121)
0.9 1.8 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.9 22.2 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.9 2.6 GO:0051305 mitotic chromosome movement towards spindle pole(GO:0007079) chromosome movement towards spindle pole(GO:0051305)
0.9 4.4 GO:0072675 osteoclast fusion(GO:0072675)
0.9 3.5 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.9 0.9 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.9 5.2 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.9 16.4 GO:0051444 negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.9 5.2 GO:0018879 biphenyl metabolic process(GO:0018879)
0.9 6.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.8 10.1 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.8 9.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.8 2.5 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.8 2.5 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541)
0.8 6.6 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.8 3.3 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.8 2.5 GO:0036446 myofibroblast differentiation(GO:0036446) cardiac fibroblast cell differentiation(GO:0060935) cardiac fibroblast cell development(GO:0060936) epicardium-derived cardiac fibroblast cell differentiation(GO:0060938) epicardium-derived cardiac fibroblast cell development(GO:0060939) regulation of myofibroblast differentiation(GO:1904760)
0.8 1.6 GO:0003419 growth plate cartilage chondrocyte proliferation(GO:0003419)
0.8 4.1 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.8 29.0 GO:0046785 microtubule polymerization(GO:0046785)
0.8 9.7 GO:0042832 defense response to protozoan(GO:0042832)
0.8 5.6 GO:0009405 pathogenesis(GO:0009405)
0.8 0.8 GO:0060947 cardiac vascular smooth muscle cell differentiation(GO:0060947)
0.8 1.6 GO:1902534 single-organism membrane invagination(GO:1902534)
0.8 17.5 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.8 1.6 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.8 2.4 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.8 3.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.8 5.5 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.8 2.4 GO:1990790 response to glial cell derived neurotrophic factor(GO:1990790) cellular response to glial cell derived neurotrophic factor(GO:1990792)
0.8 15.6 GO:0010829 negative regulation of glucose transport(GO:0010829)
0.8 5.4 GO:0060736 prostate gland growth(GO:0060736)
0.8 1.6 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.8 24.3 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.8 12.1 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.8 6.0 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.8 2.3 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.7 12.6 GO:0035587 purinergic receptor signaling pathway(GO:0035587)
0.7 3.7 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.7 21.3 GO:0030834 regulation of actin filament depolymerization(GO:0030834)
0.7 5.8 GO:0050957 equilibrioception(GO:0050957)
0.7 2.9 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.7 2.2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.7 9.4 GO:0007288 sperm axoneme assembly(GO:0007288)
0.7 8.6 GO:0032324 molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.7 19.9 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.7 4.9 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.7 3.4 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.7 5.4 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.7 3.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.7 2.7 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.7 10.6 GO:0006895 Golgi to endosome transport(GO:0006895)
0.7 11.2 GO:0019532 oxalate transport(GO:0019532) sulfate transmembrane transport(GO:1902358)
0.6 1.9 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.6 4.5 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.6 13.6 GO:0060749 mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377)
0.6 2.6 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.6 10.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.6 3.8 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.6 3.8 GO:0086036 regulation of cardiac muscle cell membrane potential(GO:0086036)
0.6 0.6 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.6 1.9 GO:0071623 negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.6 1.9 GO:0019046 viral latency(GO:0019042) release from viral latency(GO:0019046)
0.6 3.7 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.6 6.9 GO:2000352 negative regulation of endothelial cell apoptotic process(GO:2000352)
0.6 3.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.6 6.8 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.6 2.5 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.6 1.8 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.6 1.8 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.6 5.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.6 6.7 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.6 4.3 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.6 4.2 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.6 3.6 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.6 1.8 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.6 3.6 GO:0034184 positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.6 9.5 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.6 11.8 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.6 11.7 GO:0097435 fibril organization(GO:0097435)
0.6 4.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.6 1.7 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.6 2.9 GO:0071035 polyadenylation-dependent ncRNA catabolic process(GO:0043634) nuclear ncRNA surveillance(GO:0071029) nuclear retention of pre-mRNA at the site of transcription(GO:0071033) CUT catabolic process(GO:0071034) nuclear polyadenylation-dependent rRNA catabolic process(GO:0071035) CUT metabolic process(GO:0071043) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046)
0.6 4.0 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.6 3.4 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.6 7.4 GO:0006000 fructose metabolic process(GO:0006000)
0.6 1.7 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.6 7.3 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.6 6.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.6 2.8 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.6 2.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.6 2.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.5 1.1 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.5 2.7 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.5 3.8 GO:0016322 neuron remodeling(GO:0016322)
0.5 5.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.5 8.0 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.5 11.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.5 6.8 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.5 15.2 GO:0019731 antibacterial humoral response(GO:0019731)
0.5 2.6 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.5 8.3 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.5 2.6 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.5 4.7 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.5 1.0 GO:0060051 negative regulation of protein glycosylation(GO:0060051)
0.5 2.6 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.5 3.0 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.5 4.5 GO:0051532 regulation of NFAT protein import into nucleus(GO:0051532) positive regulation of NFAT protein import into nucleus(GO:0051533)
0.5 8.6 GO:0036159 inner dynein arm assembly(GO:0036159)
0.5 6.0 GO:0097205 renal filtration(GO:0097205)
0.5 1.5 GO:0036016 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.5 5.0 GO:0007520 myoblast fusion(GO:0007520)
0.5 19.1 GO:0008542 visual learning(GO:0008542)
0.5 1.0 GO:0071442 regulation of histone H3-K14 acetylation(GO:0071440) positive regulation of histone H3-K14 acetylation(GO:0071442)
0.5 2.9 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.5 12.4 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.5 1.9 GO:0042891 antibiotic transport(GO:0042891)
0.5 1.4 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.5 5.2 GO:0060412 ventricular septum morphogenesis(GO:0060412)
0.5 2.8 GO:0050917 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096) sensory perception of umami taste(GO:0050917)
0.5 2.4 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.5 12.1 GO:0002548 monocyte chemotaxis(GO:0002548)
0.5 0.9 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.5 2.8 GO:0042256 mature ribosome assembly(GO:0042256)
0.5 2.3 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.5 2.3 GO:0071373 cellular response to luteinizing hormone stimulus(GO:0071373)
0.5 1.8 GO:0002431 Fc receptor mediated stimulatory signaling pathway(GO:0002431)
0.5 0.9 GO:0007529 establishment of synaptic specificity at neuromuscular junction(GO:0007529)
0.5 1.4 GO:0071494 cellular response to UV-C(GO:0071494)
0.5 7.7 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.5 4.5 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.5 4.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.4 6.3 GO:0030252 growth hormone secretion(GO:0030252)
0.4 5.3 GO:0046599 regulation of centriole replication(GO:0046599)
0.4 5.8 GO:0007019 microtubule depolymerization(GO:0007019)
0.4 11.0 GO:0090280 positive regulation of calcium ion import(GO:0090280)
0.4 10.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.4 9.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.4 2.2 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.4 1.8 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.4 16.2 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.4 3.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.4 7.0 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.4 5.2 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.4 1.3 GO:0051697 protein delipidation(GO:0051697)
0.4 1.7 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.4 0.4 GO:0040031 snRNA modification(GO:0040031)
0.4 11.6 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.4 2.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.4 3.0 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.4 8.4 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.4 9.2 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.4 8.8 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.4 8.3 GO:1903205 regulation of hydrogen peroxide-induced cell death(GO:1903205)
0.4 1.2 GO:0016240 autophagosome docking(GO:0016240)
0.4 6.6 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.4 1.2 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.4 7.8 GO:0043029 T cell homeostasis(GO:0043029)
0.4 2.4 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.4 0.8 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.4 7.3 GO:0032274 gonadotropin secretion(GO:0032274)
0.4 0.8 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.4 4.3 GO:0060396 growth hormone receptor signaling pathway(GO:0060396)
0.4 13.7 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.4 6.6 GO:0048266 behavioral response to pain(GO:0048266)
0.4 0.8 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628)
0.4 1.2 GO:0016553 base conversion or substitution editing(GO:0016553)
0.4 7.7 GO:0030574 collagen catabolic process(GO:0030574)
0.4 3.1 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051) negative regulation of sprouting angiogenesis(GO:1903671)
0.4 3.4 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.4 6.1 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.4 9.1 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.4 2.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.4 8.3 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.4 168.5 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.4 6.8 GO:0097503 sialylation(GO:0097503)
0.4 4.1 GO:0006013 mannose metabolic process(GO:0006013)
0.4 3.4 GO:0021707 cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.4 1.9 GO:0071763 nuclear membrane organization(GO:0071763)
0.4 1.5 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.4 1.5 GO:0072161 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.4 13.7 GO:0070527 platelet aggregation(GO:0070527)
0.4 1.5 GO:1902570 protein localization to nucleolus(GO:1902570)
0.4 3.6 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.4 1.4 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.4 3.2 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.4 5.7 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.4 8.9 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.4 1.8 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.3 0.7 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.3 2.8 GO:0071371 cellular response to gonadotropin stimulus(GO:0071371)
0.3 3.4 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.3 3.1 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.3 0.7 GO:0032730 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) regulation of interleukin-1 alpha secretion(GO:0050705) positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.3 5.1 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.3 9.5 GO:2000179 positive regulation of neural precursor cell proliferation(GO:2000179)
0.3 11.4 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.3 2.7 GO:0061436 establishment of skin barrier(GO:0061436)
0.3 1.7 GO:0070986 left/right axis specification(GO:0070986)
0.3 7.3 GO:0045332 phospholipid translocation(GO:0045332)
0.3 1.0 GO:0003383 apical constriction(GO:0003383)
0.3 2.3 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.3 5.9 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.3 13.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.3 3.0 GO:0034063 stress granule assembly(GO:0034063)
0.3 1.9 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.3 3.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.3 4.7 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.3 5.7 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.3 1.6 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.3 4.4 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.3 2.8 GO:0001967 suckling behavior(GO:0001967)
0.3 2.7 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.3 9.7 GO:0048286 lung alveolus development(GO:0048286)
0.3 1.5 GO:0034349 glial cell apoptotic process(GO:0034349)
0.3 10.2 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.3 8.7 GO:0090307 mitotic spindle assembly(GO:0090307)
0.3 7.2 GO:0008088 axo-dendritic transport(GO:0008088)
0.3 1.2 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.3 4.7 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.3 0.6 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.3 3.2 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.3 9.6 GO:0002763 positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.3 1.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.3 11.8 GO:0072384 organelle transport along microtubule(GO:0072384)
0.3 1.4 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.3 4.8 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.3 0.8 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.3 1.1 GO:0051081 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.3 2.0 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.3 15.6 GO:0009408 response to heat(GO:0009408)
0.3 9.8 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.3 11.7 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.3 3.7 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.3 4.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.3 3.4 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.3 2.3 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.3 0.5 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.3 0.8 GO:1902047 polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.3 1.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.3 6.5 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.2 1.0 GO:0000733 DNA strand renaturation(GO:0000733)
0.2 2.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.2 1.2 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.2 1.4 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.2 2.4 GO:0000076 DNA replication checkpoint(GO:0000076)
0.2 0.7 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.2 2.1 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.2 7.7 GO:0051225 spindle assembly(GO:0051225)
0.2 3.0 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.2 0.7 GO:0044351 macropinocytosis(GO:0044351)
0.2 1.4 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.2 5.2 GO:0031297 replication fork processing(GO:0031297)
0.2 7.2 GO:0043462 regulation of ATPase activity(GO:0043462)
0.2 9.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.2 1.5 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.2 3.0 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.2 2.7 GO:0043489 RNA stabilization(GO:0043489)
0.2 2.7 GO:0061157 mRNA destabilization(GO:0061157)
0.2 0.6 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.2 1.0 GO:0038203 TORC2 signaling(GO:0038203)
0.2 1.8 GO:0045023 G0 to G1 transition(GO:0045023)
0.2 2.4 GO:0000042 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.2 6.4 GO:0032418 lysosome localization(GO:0032418)
0.2 6.3 GO:0006414 translational elongation(GO:0006414)
0.2 3.7 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.2 2.4 GO:0016578 histone deubiquitination(GO:0016578)
0.2 2.8 GO:0031572 mitotic G2 DNA damage checkpoint(GO:0007095) G2 DNA damage checkpoint(GO:0031572)
0.2 7.4 GO:0043966 histone H3 acetylation(GO:0043966)
0.2 5.3 GO:0018345 protein palmitoylation(GO:0018345)
0.2 1.9 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.2 4.6 GO:0000154 rRNA modification(GO:0000154)
0.2 0.4 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.2 14.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.2 0.9 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 4.7 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.2 3.6 GO:0006450 regulation of translational fidelity(GO:0006450)
0.2 3.3 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.2 1.3 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.2 2.4 GO:0070166 enamel mineralization(GO:0070166)
0.2 7.4 GO:0050715 positive regulation of cytokine secretion(GO:0050715)
0.2 2.0 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.2 0.3 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.2 1.5 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 0.7 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 1.5 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.1 0.6 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 1.7 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.1 5.2 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.1 0.4 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 0.8 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 1.9 GO:0006828 manganese ion transport(GO:0006828)
0.1 5.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.8 GO:1903306 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.1 1.8 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 4.1 GO:0006378 mRNA polyadenylation(GO:0006378)
0.1 1.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 1.7 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.8 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 5.2 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 6.9 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.1 0.7 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.1 1.6 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 1.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 1.2 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 1.5 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 0.6 GO:0006308 DNA catabolic process(GO:0006308)
0.1 0.8 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 2.4 GO:0060325 face morphogenesis(GO:0060325)
0.1 3.9 GO:0070206 protein trimerization(GO:0070206)
0.1 0.5 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1 0.3 GO:0044691 tooth eruption(GO:0044691)
0.1 2.6 GO:0032609 interferon-gamma production(GO:0032609)
0.1 0.2 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.1 1.9 GO:0030488 tRNA methylation(GO:0030488)
0.1 2.9 GO:0048512 circadian behavior(GO:0048512)
0.1 1.7 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.1 1.5 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 0.8 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.1 4.8 GO:0050821 protein stabilization(GO:0050821)
0.1 4.9 GO:0007631 feeding behavior(GO:0007631)
0.1 1.6 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.1 1.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 0.9 GO:0034453 microtubule anchoring(GO:0034453)
0.1 0.7 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.1 0.7 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.1 0.4 GO:0046710 GDP metabolic process(GO:0046710)
0.1 1.9 GO:0021762 substantia nigra development(GO:0021762)
0.1 0.1 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.1 0.8 GO:0030728 ovulation(GO:0030728)
0.1 1.4 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.1 0.4 GO:2000505 regulation of energy homeostasis(GO:2000505)
0.1 0.5 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.1 0.1 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.3 GO:0046037 GMP metabolic process(GO:0046037)
0.0 0.1 GO:0070637 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.0 0.9 GO:1990089 response to nerve growth factor(GO:1990089)
0.0 0.0 GO:0097168 mesenchymal stem cell proliferation(GO:0097168)
0.0 0.4 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 0.9 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 0.3 GO:0031424 keratinization(GO:0031424)
0.0 0.0 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.1 GO:0035855 megakaryocyte development(GO:0035855)
0.0 5.0 GO:0070489 T cell activation(GO:0042110) T cell aggregation(GO:0070489)
0.0 0.5 GO:0090382 phagosome maturation(GO:0090382)
0.0 0.3 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.5 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.3 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.0 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 1.8 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 1.3 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.2 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.3 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.3 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.8 GO:0030317 sperm motility(GO:0030317)
0.0 1.6 GO:0009615 response to virus(GO:0009615)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
11.1 44.3 GO:0005607 laminin-2 complex(GO:0005607)
9.5 105.0 GO:0005833 hemoglobin complex(GO:0005833)
8.0 31.9 GO:0097513 myosin II filament(GO:0097513)
7.9 31.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
7.3 44.0 GO:0033093 Weibel-Palade body(GO:0033093)
6.3 25.1 GO:0036398 TCR signalosome(GO:0036398) microspike(GO:0044393)
4.8 28.8 GO:0016012 sarcoglycan complex(GO:0016012)
4.6 13.9 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
4.5 26.8 GO:0030478 actin cap(GO:0030478)
3.9 27.4 GO:0090543 Flemming body(GO:0090543)
3.7 37.1 GO:0008290 F-actin capping protein complex(GO:0008290)
3.6 47.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
3.4 24.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
3.4 13.6 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
3.4 13.5 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
3.3 39.7 GO:0005861 troponin complex(GO:0005861)
3.2 9.7 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
3.0 3.0 GO:0031933 telomeric heterochromatin(GO:0031933)
2.8 16.9 GO:0005608 laminin-3 complex(GO:0005608)
2.7 8.2 GO:1902560 GMP reductase complex(GO:1902560)
2.7 24.3 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
2.7 13.3 GO:0005927 muscle tendon junction(GO:0005927)
2.7 21.2 GO:0032584 growth cone membrane(GO:0032584)
2.6 7.8 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
2.6 7.7 GO:1990423 RZZ complex(GO:1990423)
2.4 26.8 GO:0032982 myosin filament(GO:0032982)
2.4 7.3 GO:0031510 SUMO activating enzyme complex(GO:0031510)
2.4 7.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
2.2 2.2 GO:1990597 AIP1-IRE1 complex(GO:1990597)
2.1 32.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
2.0 20.1 GO:0051286 cell tip(GO:0051286)
2.0 6.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
2.0 6.0 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
1.9 5.8 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
1.9 5.8 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
1.9 5.6 GO:0097444 spine apparatus(GO:0097444)
1.8 9.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
1.8 7.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
1.7 15.6 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
1.7 8.4 GO:0034455 t-UTP complex(GO:0034455)
1.6 4.9 GO:0035101 FACT complex(GO:0035101)
1.6 17.9 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
1.6 14.6 GO:0016461 unconventional myosin complex(GO:0016461)
1.6 11.0 GO:0000796 condensin complex(GO:0000796)
1.5 6.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
1.5 13.7 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
1.5 5.8 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
1.4 13.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
1.4 7.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
1.4 53.4 GO:0001772 immunological synapse(GO:0001772)
1.4 15.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
1.4 15.0 GO:0042101 T cell receptor complex(GO:0042101)
1.4 4.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
1.4 9.5 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
1.3 6.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
1.3 6.5 GO:0005940 septin ring(GO:0005940)
1.3 20.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
1.3 6.4 GO:0098845 postsynaptic endosome(GO:0098845)
1.3 6.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
1.3 34.0 GO:0031430 M band(GO:0031430)
1.3 3.8 GO:0032398 MHC class Ib protein complex(GO:0032398)
1.2 12.5 GO:0070938 contractile ring(GO:0070938)
1.2 1.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
1.2 36.2 GO:0008305 integrin complex(GO:0008305)
1.2 4.8 GO:0034657 GID complex(GO:0034657)
1.2 5.9 GO:0043293 apoptosome(GO:0043293)
1.2 15.2 GO:0000124 SAGA complex(GO:0000124)
1.2 5.8 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
1.1 13.7 GO:0031258 lamellipodium membrane(GO:0031258)
1.1 11.2 GO:0042587 glycogen granule(GO:0042587)
1.1 5.6 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
1.1 5.5 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
1.1 12.0 GO:0044327 dendritic spine head(GO:0044327)
1.1 5.4 GO:0035061 interchromatin granule(GO:0035061)
1.1 4.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
1.1 79.0 GO:0031902 late endosome membrane(GO:0031902)
1.1 7.5 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
1.1 1.1 GO:0000346 transcription export complex(GO:0000346)
1.1 4.3 GO:0031592 centrosomal corona(GO:0031592)
1.1 7.4 GO:0008091 spectrin(GO:0008091)
1.1 12.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
1.0 8.0 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
1.0 3.0 GO:0033647 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
1.0 75.0 GO:0032432 actin filament bundle(GO:0032432)
0.9 1.9 GO:0005606 laminin-1 complex(GO:0005606)
0.9 13.9 GO:0035253 ciliary rootlet(GO:0035253)
0.9 4.6 GO:0070761 pre-snoRNP complex(GO:0070761)
0.9 3.7 GO:0033503 HULC complex(GO:0033503)
0.9 13.7 GO:0016580 Sin3 complex(GO:0016580)
0.9 2.7 GO:0097454 Schwann cell microvillus(GO:0097454)
0.9 125.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.9 2.7 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.9 4.3 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.9 10.3 GO:1990752 microtubule end(GO:1990752)
0.9 2.6 GO:0019815 B cell receptor complex(GO:0019815)
0.9 5.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.9 6.0 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.8 16.1 GO:0051233 spindle midzone(GO:0051233)
0.8 4.9 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.8 9.4 GO:0030056 hemidesmosome(GO:0030056)
0.8 24.1 GO:0008180 COP9 signalosome(GO:0008180)
0.8 4.7 GO:0036449 microtubule minus-end(GO:0036449)
0.8 19.4 GO:0042588 zymogen granule(GO:0042588)
0.8 19.3 GO:0000421 autophagosome membrane(GO:0000421)
0.8 13.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.8 8.4 GO:0016600 flotillin complex(GO:0016600)
0.7 3.7 GO:0070552 BRISC complex(GO:0070552)
0.7 4.4 GO:0097209 epidermal lamellar body(GO:0097209)
0.7 11.0 GO:0097449 astrocyte projection(GO:0097449)
0.7 5.8 GO:0031143 pseudopodium(GO:0031143)
0.7 10.9 GO:0001741 XY body(GO:0001741)
0.7 6.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.7 2.2 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.7 12.8 GO:0031672 A band(GO:0031672)
0.7 18.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.7 26.9 GO:0005720 nuclear heterochromatin(GO:0005720)
0.7 5.5 GO:0016589 NURF complex(GO:0016589)
0.7 4.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.7 2.7 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.7 3.4 GO:0097361 CIA complex(GO:0097361)
0.7 18.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.7 30.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.7 21.4 GO:0005921 gap junction(GO:0005921)
0.6 6.5 GO:0045180 basal cortex(GO:0045180)
0.6 4.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.6 10.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.6 11.2 GO:0001520 outer dense fiber(GO:0001520)
0.6 36.3 GO:0031225 anchored component of membrane(GO:0031225)
0.6 27.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.6 15.9 GO:0044295 axonal growth cone(GO:0044295)
0.6 3.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.5 19.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.5 4.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.5 3.3 GO:0005879 axonemal microtubule(GO:0005879)
0.5 3.8 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.5 5.4 GO:0071564 npBAF complex(GO:0071564)
0.5 4.8 GO:0033270 paranode region of axon(GO:0033270)
0.5 11.6 GO:0034706 sodium channel complex(GO:0034706)
0.5 4.2 GO:0070187 telosome(GO:0070187)
0.5 25.7 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.5 9.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.5 46.1 GO:0016605 PML body(GO:0016605)
0.5 12.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.5 5.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.5 2.8 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.5 5.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.5 9.0 GO:0031091 platelet alpha granule(GO:0031091)
0.5 3.2 GO:0042382 paraspeckles(GO:0042382)
0.4 4.4 GO:0002177 manchette(GO:0002177)
0.4 2.6 GO:0030914 STAGA complex(GO:0030914)
0.4 32.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.4 2.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.4 30.8 GO:0005581 collagen trimer(GO:0005581)
0.4 1.7 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.4 4.9 GO:0000812 Swr1 complex(GO:0000812)
0.4 5.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.4 11.2 GO:0030286 dynein complex(GO:0030286)
0.4 2.8 GO:0070652 HAUS complex(GO:0070652)
0.4 4.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.4 42.1 GO:0030017 sarcomere(GO:0030017)
0.4 4.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.4 0.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.4 22.0 GO:0034707 chloride channel complex(GO:0034707)
0.4 0.8 GO:0000974 Prp19 complex(GO:0000974)
0.4 6.6 GO:0005614 interstitial matrix(GO:0005614)
0.4 7.4 GO:0001533 cornified envelope(GO:0001533)
0.4 10.5 GO:0002102 podosome(GO:0002102)
0.3 3.8 GO:0031083 BLOC-1 complex(GO:0031083)
0.3 7.2 GO:0001891 phagocytic cup(GO:0001891)
0.3 1.7 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.3 5.5 GO:0005686 U2 snRNP(GO:0005686)
0.3 1.3 GO:0035363 histone locus body(GO:0035363)
0.3 80.1 GO:0005874 microtubule(GO:0005874)
0.3 0.9 GO:0000811 GINS complex(GO:0000811)
0.3 5.0 GO:0001673 male germ cell nucleus(GO:0001673)
0.3 1.8 GO:0098839 postsynaptic density membrane(GO:0098839)
0.3 0.9 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.3 3.9 GO:0005682 U5 snRNP(GO:0005682)
0.3 2.4 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.3 2.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.3 1.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.3 2.6 GO:0032009 early phagosome(GO:0032009)
0.3 3.3 GO:0032279 asymmetric synapse(GO:0032279)
0.3 1.4 GO:0089701 U2AF(GO:0089701)
0.3 24.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.3 0.8 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.3 17.4 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.3 63.3 GO:0000790 nuclear chromatin(GO:0000790)
0.3 6.5 GO:0034451 centriolar satellite(GO:0034451)
0.3 4.8 GO:0019013 viral nucleocapsid(GO:0019013)
0.3 66.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.2 13.7 GO:0016234 inclusion body(GO:0016234)
0.2 2.0 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.2 6.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 11.6 GO:0000922 spindle pole(GO:0000922)
0.2 2.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 1.6 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 1.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.2 2.1 GO:0097542 ciliary tip(GO:0097542)
0.2 2.9 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 1.6 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 0.6 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 1.2 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.2 42.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.2 5.3 GO:0035869 ciliary transition zone(GO:0035869)
0.2 0.7 GO:1990745 GARP complex(GO:0000938) EARP complex(GO:1990745)
0.2 4.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 14.5 GO:0000775 chromosome, centromeric region(GO:0000775)
0.2 0.5 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.2 6.1 GO:0045171 intercellular bridge(GO:0045171)
0.2 11.3 GO:0022626 cytosolic ribosome(GO:0022626)
0.1 8.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 4.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 1.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 1.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.3 GO:0071141 SMAD protein complex(GO:0071141)
0.1 3.7 GO:0031519 PcG protein complex(GO:0031519)
0.1 0.4 GO:0097227 septin complex(GO:0031105) sperm annulus(GO:0097227)
0.1 14.3 GO:0031012 extracellular matrix(GO:0031012)
0.1 5.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 1.9 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.4 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1 65.2 GO:0016604 nuclear body(GO:0016604)
0.1 1.0 GO:0031932 TORC2 complex(GO:0031932)
0.1 1.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 1.5 GO:0035861 site of double-strand break(GO:0035861)
0.1 1.6 GO:0042629 mast cell granule(GO:0042629)
0.1 0.3 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.3 GO:0031417 NatC complex(GO:0031417)
0.1 0.7 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 1.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 3.2 GO:0005814 centriole(GO:0005814)
0.1 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 1.7 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 1.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.3 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 1.7 GO:0005795 Golgi stack(GO:0005795)
0.0 0.1 GO:0031209 SCAR complex(GO:0031209)
0.0 0.4 GO:0000145 exocyst(GO:0000145)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
12.6 37.7 GO:0031720 haptoglobin binding(GO:0031720)
10.4 31.1 GO:0035939 microsatellite binding(GO:0035939)
7.0 126.9 GO:0044548 S100 protein binding(GO:0044548)
6.7 80.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
6.4 25.5 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
6.2 18.5 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
6.0 24.1 GO:0035877 death effector domain binding(GO:0035877)
5.7 40.2 GO:0004111 creatine kinase activity(GO:0004111)
5.7 39.7 GO:0031014 troponin T binding(GO:0031014)
5.6 16.8 GO:0016403 dimethylargininase activity(GO:0016403)
5.6 67.3 GO:0005344 oxygen transporter activity(GO:0005344)
5.6 22.4 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
5.4 16.2 GO:0048030 disaccharide binding(GO:0048030)
5.1 20.4 GO:0042610 CD8 receptor binding(GO:0042610)
5.0 15.1 GO:0033222 xylose binding(GO:0033222)
4.9 14.6 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
4.4 17.6 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
4.4 26.4 GO:0004126 cytidine deaminase activity(GO:0004126)
4.4 43.7 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
4.2 12.7 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
4.1 12.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
4.0 19.8 GO:0043120 tumor necrosis factor binding(GO:0043120)
3.8 19.2 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
3.8 19.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
3.6 14.6 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
3.5 28.0 GO:0071253 connexin binding(GO:0071253)
3.4 17.0 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
3.3 19.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
3.2 19.2 GO:0016361 activin receptor activity, type I(GO:0016361)
3.2 32.0 GO:0042609 CD4 receptor binding(GO:0042609)
3.2 22.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
3.2 35.0 GO:0032036 myosin heavy chain binding(GO:0032036)
3.2 9.5 GO:0034041 sterol-transporting ATPase activity(GO:0034041) glycoprotein transporter activity(GO:0034437)
3.0 76.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
3.0 9.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
3.0 21.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
3.0 33.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
2.9 17.5 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
2.9 11.5 GO:0003872 6-phosphofructokinase activity(GO:0003872)
2.9 11.5 GO:0004743 pyruvate kinase activity(GO:0004743)
2.9 14.3 GO:0019960 C-X3-C chemokine binding(GO:0019960)
2.7 8.2 GO:0046592 polyamine oxidase activity(GO:0046592)
2.7 8.2 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
2.7 35.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
2.7 5.3 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
2.7 21.2 GO:0004859 phospholipase inhibitor activity(GO:0004859)
2.6 7.9 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
2.6 13.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
2.6 7.7 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
2.6 7.7 GO:0046980 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
2.6 33.2 GO:0030215 semaphorin receptor binding(GO:0030215)
2.5 17.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
2.4 19.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
2.4 9.5 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
2.4 7.1 GO:0031750 D3 dopamine receptor binding(GO:0031750)
2.3 45.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
2.2 10.9 GO:0042731 PH domain binding(GO:0042731)
2.1 12.8 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
2.1 14.8 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
2.0 14.3 GO:0030274 LIM domain binding(GO:0030274)
2.0 20.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
2.0 31.6 GO:0051400 BH domain binding(GO:0051400)
2.0 17.6 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
1.9 3.8 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
1.9 45.8 GO:0005112 Notch binding(GO:0005112)
1.9 15.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
1.9 26.4 GO:0031432 titin binding(GO:0031432)
1.9 9.4 GO:0048495 Roundabout binding(GO:0048495)
1.8 25.8 GO:0042043 neurexin family protein binding(GO:0042043)
1.8 5.5 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
1.8 36.1 GO:0017049 GTP-Rho binding(GO:0017049)
1.8 7.1 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
1.7 10.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
1.7 6.7 GO:0010465 nerve growth factor receptor activity(GO:0010465) G-protein coupled neurotensin receptor activity(GO:0016492)
1.7 16.5 GO:0003680 AT DNA binding(GO:0003680)
1.6 25.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
1.6 7.9 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
1.6 6.4 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
1.6 3.2 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
1.6 6.2 GO:0015265 urea channel activity(GO:0015265)
1.6 6.2 GO:0045159 myosin II binding(GO:0045159)
1.5 18.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
1.5 9.2 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
1.5 4.5 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
1.5 9.0 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
1.5 2.9 GO:0022841 potassium ion leak channel activity(GO:0022841)
1.5 5.9 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
1.4 2.8 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
1.4 35.5 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
1.4 6.8 GO:0031849 olfactory receptor binding(GO:0031849)
1.3 9.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
1.3 8.0 GO:0036374 gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
1.3 4.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
1.3 3.9 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
1.3 17.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
1.3 13.0 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
1.3 15.5 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
1.3 3.8 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
1.3 43.3 GO:0008307 structural constituent of muscle(GO:0008307)
1.3 11.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
1.3 3.8 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
1.2 13.7 GO:0008131 primary amine oxidase activity(GO:0008131)
1.2 38.5 GO:0043236 laminin binding(GO:0043236)
1.2 7.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
1.2 31.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
1.2 4.8 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
1.2 4.7 GO:0051425 PTB domain binding(GO:0051425)
1.2 21.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
1.2 4.7 GO:0032896 stearoyl-CoA 9-desaturase activity(GO:0004768) palmitoyl-CoA 9-desaturase activity(GO:0032896)
1.1 8.0 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
1.1 8.0 GO:0003896 DNA primase activity(GO:0003896)
1.1 9.0 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
1.1 3.4 GO:0042903 tubulin deacetylase activity(GO:0042903)
1.1 15.6 GO:0003688 DNA replication origin binding(GO:0003688)
1.1 6.7 GO:0004994 somatostatin receptor activity(GO:0004994)
1.1 11.1 GO:0019957 C-C chemokine binding(GO:0019957)
1.1 3.3 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
1.1 20.7 GO:0001618 virus receptor activity(GO:0001618)
1.1 4.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
1.1 6.5 GO:0050692 DBD domain binding(GO:0050692)
1.1 11.6 GO:0004017 adenylate kinase activity(GO:0004017)
1.0 9.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
1.0 3.1 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
1.0 3.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
1.0 8.3 GO:1990459 transferrin receptor binding(GO:1990459)
1.0 8.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
1.0 7.3 GO:0044388 small protein activating enzyme binding(GO:0044388)
1.0 3.1 GO:0031770 growth hormone-releasing hormone receptor binding(GO:0031770)
1.0 19.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
1.0 4.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
1.0 5.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315) sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
1.0 4.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
1.0 12.1 GO:0035198 miRNA binding(GO:0035198)
1.0 6.0 GO:0005138 interleukin-6 receptor binding(GO:0005138)
1.0 7.0 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
1.0 5.9 GO:1990226 histone methyltransferase binding(GO:1990226)
1.0 5.8 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
1.0 3.8 GO:0031013 troponin I binding(GO:0031013)
1.0 5.7 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
1.0 2.9 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.9 3.8 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.9 14.1 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.9 16.0 GO:0071617 lysophospholipid acyltransferase activity(GO:0071617)
0.9 10.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.9 10.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.9 16.3 GO:0005522 profilin binding(GO:0005522)
0.9 7.2 GO:0001164 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.9 10.7 GO:0042301 phosphate ion binding(GO:0042301)
0.9 77.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.9 21.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.9 3.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.9 2.6 GO:0005135 interleukin-3 receptor binding(GO:0005135)
0.9 3.5 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.9 17.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.9 25.6 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.8 19.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.8 2.4 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.8 8.6 GO:0016783 sulfurtransferase activity(GO:0016783)
0.8 3.1 GO:1990955 G-rich single-stranded DNA binding(GO:1990955)
0.8 10.6 GO:0003785 actin monomer binding(GO:0003785)
0.8 23.4 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.8 9.0 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.7 11.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.7 7.4 GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.7 3.7 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.7 1.5 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.7 3.7 GO:0050816 phosphothreonine binding(GO:0050816)
0.7 7.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.7 16.9 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.7 5.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.7 2.8 GO:0061665 SUMO ligase activity(GO:0061665)
0.7 16.9 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.7 33.7 GO:0070888 E-box binding(GO:0070888)
0.7 2.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.7 21.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.7 0.7 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.7 5.6 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.7 2.7 GO:0036033 mediator complex binding(GO:0036033)
0.7 30.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.7 7.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.7 10.8 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.7 30.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.7 3.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.7 2.6 GO:0032190 acrosin binding(GO:0032190)
0.6 1.9 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.6 1.9 GO:0042895 antibiotic transporter activity(GO:0042895)
0.6 1.9 GO:0001847 opsonin receptor activity(GO:0001847)
0.6 5.0 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.6 6.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.6 3.7 GO:0050700 CARD domain binding(GO:0050700)
0.6 1.8 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.6 12.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.6 3.5 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.6 1.7 GO:0042608 T cell receptor binding(GO:0042608)
0.6 4.1 GO:0000405 bubble DNA binding(GO:0000405)
0.6 1.7 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.6 21.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.6 6.6 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.5 4.3 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.5 4.9 GO:1990446 U1 snRNP binding(GO:1990446)
0.5 4.8 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.5 37.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.5 4.3 GO:0043515 kinetochore binding(GO:0043515)
0.5 8.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.5 7.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.5 1.6 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.5 2.1 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.5 2.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.5 4.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.5 41.3 GO:0003777 microtubule motor activity(GO:0003777)
0.5 121.2 GO:0005096 GTPase activator activity(GO:0005096)
0.5 5.4 GO:0008097 5S rRNA binding(GO:0008097)
0.5 4.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.5 53.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.5 1.9 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.5 12.9 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.5 5.2 GO:0015643 toxic substance binding(GO:0015643)
0.5 3.3 GO:0017166 vinculin binding(GO:0017166)
0.5 1.8 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.5 4.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.4 6.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.4 7.9 GO:0005521 lamin binding(GO:0005521)
0.4 1.3 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.4 2.2 GO:0046625 sphingolipid binding(GO:0046625)
0.4 3.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.4 11.1 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.4 2.5 GO:0043208 glycosphingolipid binding(GO:0043208)
0.4 14.4 GO:0003774 motor activity(GO:0003774)
0.4 6.2 GO:0015926 glucosidase activity(GO:0015926)
0.4 6.5 GO:0017136 NAD-dependent histone deacetylase activity(GO:0017136)
0.4 4.8 GO:0005523 tropomyosin binding(GO:0005523)
0.4 21.2 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.4 3.2 GO:0008517 folic acid transporter activity(GO:0008517)
0.4 103.9 GO:0015631 tubulin binding(GO:0015631)
0.4 2.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.4 7.0 GO:0071889 14-3-3 protein binding(GO:0071889)
0.4 7.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.4 2.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.4 1.2 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.4 1.9 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.4 6.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.4 4.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.4 19.0 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.4 1.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.4 1.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.4 26.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.4 1.8 GO:0015616 DNA translocase activity(GO:0015616)
0.3 16.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.3 0.7 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.3 4.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.3 11.1 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.3 2.7 GO:0070411 I-SMAD binding(GO:0070411)
0.3 7.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.3 1.0 GO:0009378 four-way junction helicase activity(GO:0009378)
0.3 3.3 GO:0051378 serotonin binding(GO:0051378)
0.3 3.0 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.3 1.3 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.3 9.8 GO:0005518 collagen binding(GO:0005518)
0.3 2.6 GO:0035325 Toll-like receptor binding(GO:0035325)
0.3 40.2 GO:0008201 heparin binding(GO:0008201)
0.3 23.8 GO:0031490 chromatin DNA binding(GO:0031490)
0.3 15.1 GO:0051018 protein kinase A binding(GO:0051018)
0.3 12.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.3 15.1 GO:0031072 heat shock protein binding(GO:0031072)
0.3 2.7 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.3 2.7 GO:0005381 iron ion transmembrane transporter activity(GO:0005381) ferrous iron transmembrane transporter activity(GO:0015093)
0.3 2.6 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.3 3.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.3 8.7 GO:0017025 TBP-class protein binding(GO:0017025)
0.3 8.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.3 6.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 2.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.3 10.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.3 14.6 GO:0019003 GDP binding(GO:0019003)
0.3 0.8 GO:0042979 ornithine decarboxylase activator activity(GO:0042978) ornithine decarboxylase regulator activity(GO:0042979)
0.3 9.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.2 3.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 3.2 GO:0005537 mannose binding(GO:0005537)
0.2 5.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.2 4.4 GO:0019239 deaminase activity(GO:0019239)
0.2 2.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 4.0 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 1.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 4.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 4.1 GO:0004623 phospholipase A2 activity(GO:0004623)
0.2 13.7 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.2 0.7 GO:0022840 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.2 1.4 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.2 4.3 GO:0005234 ionotropic glutamate receptor activity(GO:0004970) extracellular-glutamate-gated ion channel activity(GO:0005234)
0.2 2.5 GO:0019864 IgG binding(GO:0019864)
0.2 2.4 GO:0097200 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153) cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.2 7.1 GO:0030515 snoRNA binding(GO:0030515)
0.2 11.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 1.9 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.2 3.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2 5.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 2.9 GO:0001056 RNA polymerase III activity(GO:0001056)
0.2 2.7 GO:0050681 androgen receptor binding(GO:0050681)
0.2 26.6 GO:0005057 receptor signaling protein activity(GO:0005057)
0.2 4.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 3.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 3.6 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.2 1.6 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.2 0.5 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.2 5.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.2 7.4 GO:0035064 methylated histone binding(GO:0035064)
0.2 7.8 GO:0004386 helicase activity(GO:0004386)
0.2 2.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 3.0 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.2 14.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 2.2 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.2 2.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 10.6 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.1 1.9 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.1 6.3 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 10.7 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 11.5 GO:0005516 calmodulin binding(GO:0005516)
0.1 10.6 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 0.9 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 5.7 GO:0000049 tRNA binding(GO:0000049)
0.1 0.9 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 9.6 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.1 8.4 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 3.1 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.1 0.9 GO:0070717 poly-purine tract binding(GO:0070717)
0.1 11.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 3.9 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.1 7.7 GO:0051015 actin filament binding(GO:0051015)
0.1 9.9 GO:0042393 histone binding(GO:0042393)
0.1 0.6 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.4 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 1.0 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 15.1 GO:0045296 cadherin binding(GO:0045296)
0.1 1.4 GO:0034061 DNA polymerase activity(GO:0034061)
0.1 3.5 GO:0019905 syntaxin binding(GO:0019905)
0.1 2.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 3.6 GO:0008237 metallopeptidase activity(GO:0008237)
0.1 0.5 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 0.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 1.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 12.9 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.1 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.6 GO:0070403 NAD+ binding(GO:0070403)
0.1 12.9 GO:0005525 GTP binding(GO:0005525)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 13.5 GO:0003682 chromatin binding(GO:0003682)
0.0 1.7 GO:0016247 channel regulator activity(GO:0016247)
0.0 0.4 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.4 GO:0015216 purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.4 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 2.9 GO:0030246 carbohydrate binding(GO:0030246)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 73.9 PID S1P S1P4 PATHWAY S1P4 pathway
3.8 64.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
2.4 9.8 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
2.4 23.9 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
2.2 31.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
2.2 57.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
2.1 21.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
1.8 31.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
1.8 28.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
1.7 8.6 ST STAT3 PATHWAY STAT3 Pathway
1.6 16.3 PID S1P S1P1 PATHWAY S1P1 pathway
1.6 32.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
1.5 36.9 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
1.4 109.4 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
1.4 40.0 PID FAS PATHWAY FAS (CD95) signaling pathway
1.4 16.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
1.4 38.0 PID RAS PATHWAY Regulation of Ras family activation
1.3 38.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
1.3 59.8 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
1.3 5.2 PID PTP1B PATHWAY Signaling events mediated by PTP1B
1.2 18.7 PID GMCSF PATHWAY GMCSF-mediated signaling events
1.2 3.7 PID IL5 PATHWAY IL5-mediated signaling events
1.2 56.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
1.1 169.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
1.1 2.2 ST JAK STAT PATHWAY Jak-STAT Pathway
1.1 16.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
1.0 15.6 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
1.0 47.0 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
1.0 17.3 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
1.0 18.3 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
1.0 7.6 PID EPO PATHWAY EPO signaling pathway
0.9 18.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.9 5.5 PID IL23 PATHWAY IL23-mediated signaling events
0.9 38.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.9 12.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.9 16.8 PID IFNG PATHWAY IFN-gamma pathway
0.9 37.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.9 8.8 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.9 17.5 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.9 16.2 PID ALK1 PATHWAY ALK1 signaling events
0.8 14.4 PID INSULIN PATHWAY Insulin Pathway
0.8 2.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.8 35.6 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.8 15.8 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.8 7.8 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.8 26.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.8 20.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.8 37.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.7 6.7 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.7 8.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.7 12.2 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.6 15.4 PID BARD1 PATHWAY BARD1 signaling events
0.6 12.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.6 3.7 PID MYC PATHWAY C-MYC pathway
0.6 22.6 PID P53 REGULATION PATHWAY p53 pathway
0.6 11.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.6 21.8 PID ATM PATHWAY ATM pathway
0.6 6.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.6 6.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.5 3.7 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.5 5.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.5 1.5 PID IL3 PATHWAY IL3-mediated signaling events
0.5 19.7 PID PLK1 PATHWAY PLK1 signaling events
0.5 15.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.5 21.0 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.5 0.9 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.5 127.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.5 20.0 PID NOTCH PATHWAY Notch signaling pathway
0.4 5.6 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.4 19.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.4 4.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.4 5.4 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.4 8.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.4 91.2 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.4 3.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.4 4.4 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.3 2.7 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.3 11.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.3 8.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.3 8.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.3 2.6 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.3 3.8 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.3 10.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 3.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.2 2.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2 3.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 3.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.2 6.6 PID AURORA B PATHWAY Aurora B signaling
0.2 36.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 8.1 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.2 4.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 4.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.2 3.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.2 0.9 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 1.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 3.6 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 0.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 1.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 0.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 3.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 0.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 1.3 PID ARF 3PATHWAY Arf1 pathway
0.1 1.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 0.9 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.6 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 41.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
2.4 7.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
2.4 92.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
2.3 36.9 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
2.2 17.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
2.1 34.9 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
1.9 52.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
1.5 52.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
1.4 42.8 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
1.4 2.8 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
1.4 12.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
1.4 25.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
1.4 41.8 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
1.4 16.5 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
1.3 25.0 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
1.3 6.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
1.2 6.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
1.2 7.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
1.2 23.6 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
1.2 29.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
1.1 14.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
1.1 6.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
1.1 15.7 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
1.1 17.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
1.1 37.2 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
1.1 17.3 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
1.1 18.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
1.1 10.7 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
1.1 55.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
1.1 102.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
1.0 7.2 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
1.0 28.8 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
1.0 10.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
1.0 8.0 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.9 43.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.9 6.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.9 43.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.8 21.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.8 10.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.8 24.0 REACTOME KINESINS Genes involved in Kinesins
0.8 21.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.8 7.0 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.8 12.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.8 8.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.7 17.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.7 13.0 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.7 9.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.7 12.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.7 12.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.7 13.0 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.7 30.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.6 8.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.6 2.6 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.6 26.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.6 10.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.6 7.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.6 22.7 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.6 13.5 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.5 5.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.5 38.9 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.5 9.0 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.5 4.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.5 29.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.5 12.0 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.5 4.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.5 8.0 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.5 5.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.5 11.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.5 12.9 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.5 51.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.5 1.8 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.4 21.0 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.4 2.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.4 4.9 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.4 5.2 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.4 18.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.4 3.3 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.4 15.3 REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH Genes involved in NCAM signaling for neurite out-growth
0.4 6.5 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.4 15.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.4 3.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.4 14.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.4 1.9 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.4 13.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.4 2.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.4 3.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.4 11.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.4 4.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.4 8.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.4 10.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.3 2.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.3 1.4 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.3 6.5 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.3 19.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.3 15.9 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.3 0.9 REACTOME DNA STRAND ELONGATION Genes involved in DNA strand elongation
0.3 4.3 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.3 1.8 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.3 3.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.3 9.5 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.3 3.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.3 21.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.3 25.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.3 1.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.3 3.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.2 2.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 9.3 REACTOME PROTEIN FOLDING Genes involved in Protein folding
0.2 4.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.2 1.9 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 5.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.2 1.9 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.2 2.6 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.2 5.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.2 3.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 3.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 3.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 0.7 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.2 2.8 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.2 2.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2 2.0 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 4.0 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 2.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 2.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 4.9 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.1 4.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 1.6 REACTOME RNA POL II PRE TRANSCRIPTION EVENTS Genes involved in RNA Polymerase II Pre-transcription Events
0.1 1.5 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.1 4.5 REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.1 0.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 1.8 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 2.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 6.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 4.2 REACTOME TRANSLATION Genes involved in Translation
0.1 0.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.7 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 0.7 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 1.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 3.6 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.0 3.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.6 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.1 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.2 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination