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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Isl2

Z-value: 0.56

Motif logo

Transcription factors associated with Isl2

Gene Symbol Gene ID Gene Info
ENSRNOG00000015336 ISL LIM homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Isl2rn6_v1_chr8_+_60117729_601177290.342.8e-10Click!

Activity profile of Isl2 motif

Sorted Z-values of Isl2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_28164326 9.78 ENSRNOT00000088165
solute carrier family 26 member 7
chr5_+_28485619 9.60 ENSRNOT00000093341
ENSRNOT00000093129
uncharacterized LOC100912373
chr16_-_49574314 9.49 ENSRNOT00000017568
ENSRNOT00000085535
ENSRNOT00000017054
PDZ and LIM domain 3
chr3_+_143119687 9.25 ENSRNOT00000006608
cystatin 12
chr5_-_115387377 9.12 ENSRNOT00000036030
ENSRNOT00000077492
similar to hypothetical protein MGC34837
chr10_+_84135116 8.61 ENSRNOT00000031035
homeo box B7
chr1_+_128637049 8.37 ENSRNOT00000018639
tetratricopeptide repeat domain 23
chr1_-_227457629 7.71 ENSRNOT00000035910
ENSRNOT00000073770
membrane spanning 4-domains A5
chr16_-_24951612 7.63 ENSRNOT00000018987
transketolase-like 2
chr4_+_29535852 7.35 ENSRNOT00000087619
collagen, type I, alpha 2
chr14_+_34389991 7.06 ENSRNOT00000002953
phosducin-like 2
chr1_+_128606770 6.83 ENSRNOT00000073355
tetratricopeptide repeat domain 23
chr6_-_42002819 6.60 ENSRNOT00000032417
growth regulation by estrogen in breast cancer 1
chr4_-_163762434 6.49 ENSRNOT00000081854
immunoreceptor Ly49si1
chr1_-_237910012 6.37 ENSRNOT00000023664
annexin A1
chr14_-_21748356 6.36 ENSRNOT00000002670
calcium binding protein, spermatid associated 1
chr20_+_17750744 6.24 ENSRNOT00000000745
similar to RIKEN cDNA 1700049L16
chr9_-_105376935 6.24 ENSRNOT00000043386
solute carrier organic anion transporter family, member 6d1
chr13_-_74005486 6.21 ENSRNOT00000090173

chr14_+_17228856 5.99 ENSRNOT00000003082
C-X-C motif chemokine ligand 9
chr13_-_105684374 5.99 ENSRNOT00000073142
spermatogenesis associated 17
chr13_-_83457888 5.93 ENSRNOT00000076289
ENSRNOT00000004065
SFT2 domain containing 2
chr1_+_101603222 5.79 ENSRNOT00000033278
izumo sperm-egg fusion 1
chr4_-_164015365 5.68 ENSRNOT00000078121
immunoreceptor Ly49si2
chr4_+_1470716 5.62 ENSRNOT00000044223
olfactory receptor 1235
chr19_-_42180362 5.60 ENSRNOT00000089515
polyamine modulated factor 1 binding protein 1
chr5_+_133896141 5.60 ENSRNOT00000011434
PDZK1 interacting protein 1
chr9_-_104870225 5.54 ENSRNOT00000065171
solute carrier organic anion transporter family, member 6d1
chr1_-_54854353 5.49 ENSRNOT00000072895
sperm motility kinase 2A
chr9_-_104870382 5.46 ENSRNOT00000084398
solute carrier organic anion transporter family, member 6d1
chr17_+_47302272 5.22 ENSRNOT00000090021
NME/NM23 family member 8
chr16_+_72010106 5.15 ENSRNOT00000058330
ADAM metallopeptidase domain 5
chr5_-_113880911 5.13 ENSRNOT00000029441
equatorin
chr17_+_89452814 5.11 ENSRNOT00000058760
similar to MAP/microtubule affinity-regulating kinase 4 (MAP/microtubule affinity-regulating kinase like 1)
chr15_+_80040842 5.08 ENSRNOT00000043065
similar to RIKEN cDNA 4921530L21
chr1_-_14117021 5.03 ENSRNOT00000004344
similar to hypothetical protein 4933423E17
chr8_+_79638696 5.02 ENSRNOT00000085959
dyslexia susceptibility 1 candidate 1
chr17_-_42031265 4.78 ENSRNOT00000068021
doublecortin domain containing 2
chr3_-_37854561 4.68 ENSRNOT00000076095
nebulin
chr1_+_201337416 4.67 ENSRNOT00000067742
BTB domain containing 16
chr9_-_80167033 4.57 ENSRNOT00000023530
insulin-like growth factor binding protein 5
chr14_-_77810147 4.56 ENSRNOT00000035427
cytokine like 1
chr2_+_2729829 4.55 ENSRNOT00000017068
spermatogenesis associated 9
chr5_-_129175597 4.51 ENSRNOT00000012112
hypothetical protein LOC689589
chr8_+_117170620 4.50 ENSRNOT00000075271
hypothetical LOC498675
chr6_+_101288951 4.48 ENSRNOT00000046901
RGD1562540
chr17_+_47301511 4.34 ENSRNOT00000092051
ENSRNOT00000087178
NME/NM23 family member 8
chr9_-_104467973 4.33 ENSRNOT00000026099
solute carrier organic anion transporter family member 6B1
chrX_-_159841072 4.29 ENSRNOT00000001158
Rac/Cdc42 guanine nucleotide exchange factor 6
chr7_-_124929025 4.21 ENSRNOT00000015447
EF-hand calcium binding domain 6
chr9_+_53013413 4.13 ENSRNOT00000005313
ankyrin and armadillo repeat containing
chrX_+_25737292 4.05 ENSRNOT00000004893
similar to RIKEN cDNA 4933400A11
chr1_-_67284864 4.04 ENSRNOT00000082908
similar to zinc finger and SCAN domain containing 4
chr9_-_80166807 4.02 ENSRNOT00000079493
insulin-like growth factor binding protein 5
chr8_+_22559098 4.01 ENSRNOT00000041091
hypothetical protein LOC691141
chr17_-_14627937 3.98 ENSRNOT00000020532
osteoglycin
chr15_-_35153804 3.86 ENSRNOT00000050660
granzyme N
chr2_-_157035483 3.80 ENSRNOT00000076491
similar to RalA binding protein 1
chrX_-_63999622 3.78 ENSRNOT00000090902
protein gar2-like
chr10_-_13716931 3.73 ENSRNOT00000060818
ATP-binding cassette, subfamily A (ABC1), member 17
chr1_+_253221812 3.67 ENSRNOT00000085880
ENSRNOT00000054753
kinesin family member 20B
chrX_-_124162058 3.65 ENSRNOT00000071436
similar to B-cell translocation gene 1
chr5_+_103251986 3.61 ENSRNOT00000008757
centlein
chr10_-_10767389 3.58 ENSRNOT00000066754
small integral membrane protein 22
chr1_+_18491384 3.49 ENSRNOT00000079138
ENSRNOT00000014917
laminin subunit alpha 2
chr4_-_176606382 3.49 ENSRNOT00000065576
RecQ like helicase
chr1_+_252284464 3.47 ENSRNOT00000027969
lipase F, gastric type
chr6_-_99273033 3.40 ENSRNOT00000088808
testis expressed 21
chr19_-_49510901 3.39 ENSRNOT00000082929
ENSRNOT00000079969
hypothetical protein LOC687399
chr9_+_8054466 3.33 ENSRNOT00000081513
adhesion G protein-coupled receptor E4
chr2_-_181900856 3.32 ENSRNOT00000082156
lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)
chrX_+_84064427 3.29 ENSRNOT00000046364
zinc finger protein 711
chr10_+_56524468 3.26 ENSRNOT00000022041
G protein pathway suppressor 2
chrX_-_98095663 3.19 ENSRNOT00000004491
RNA binding motif 31, Y-linked
chr16_-_29936307 3.15 ENSRNOT00000088707
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr4_+_61814974 3.09 ENSRNOT00000074951
aldo-keto reductase family 1 member B10
chr7_-_143167772 3.06 ENSRNOT00000011374
keratin 85
chrX_+_77143892 3.04 ENSRNOT00000085227
ATPase copper transporting alpha
chr2_-_216348194 3.02 ENSRNOT00000087839
pancreatic alpha-amylase-like
chr6_-_94932806 2.98 ENSRNOT00000006346
coiled-coil domain containing 175
chr7_+_38858062 2.91 ENSRNOT00000006234
keratocan
chr10_+_61685645 2.89 ENSRNOT00000003933
MAX network transcriptional repressor
chr9_+_60900213 2.88 ENSRNOT00000017859
coiled-coil domain containing 150
chr9_+_8052210 2.86 ENSRNOT00000073659
adhesion G protein-coupled receptor E4
chr9_-_27452902 2.85 ENSRNOT00000018325
glutathione S-transferase alpha 1
chr3_+_8430829 2.85 ENSRNOT00000090440
ENSRNOT00000060969
cerebral endothelial cell adhesion molecule
chr1_+_79631668 2.82 ENSRNOT00000083546
ENSRNOT00000035286
MHC I like leukocyte 1
chr1_-_127292090 2.81 ENSRNOT00000016959
leucine-rich repeat kinase 1
chr14_-_21299068 2.79 ENSRNOT00000065778
amelotin
chr2_+_122877286 2.76 ENSRNOT00000033080
arylsulfatase E
chr9_-_70449796 2.69 ENSRNOT00000086391
malate dehydrogenase 1B
chr11_-_28900376 2.69 ENSRNOT00000061606
keratin associated protein 16-5
chr14_-_21810314 2.68 ENSRNOT00000002671
casein kappa
chr10_-_98469799 2.65 ENSRNOT00000087502
ENSRNOT00000088646
ATP binding cassette subfamily A member 9
chr5_-_108747666 2.63 ENSRNOT00000072732
zinc finger protein 353
chr10_-_29026002 2.62 ENSRNOT00000005070
pituitary tumor-transforming 1
chr11_+_15081774 2.58 ENSRNOT00000009911
ubiquitin carboxyl-terminal hydrolase 25-like
chr4_-_184096806 2.52 ENSRNOT00000055433
mKIAA1238 protein-like
chr4_-_164899041 2.51 ENSRNOT00000090316
Ly49 inhibitory receptor 2
chr8_-_40883880 2.50 ENSRNOT00000075593
disks large homolog 5-like
chr2_-_192288568 2.49 ENSRNOT00000067346

chr7_+_2300434 2.47 ENSRNOT00000071785

chr2_-_216382244 2.41 ENSRNOT00000086695
ENSRNOT00000087259
pancreatic alpha-amylase-like
chr4_-_50693869 2.39 ENSRNOT00000064228
ring finger protein 148
chr4_-_164304532 2.38 ENSRNOT00000089484
Ly49 inhibitory receptor 5
chr1_+_80028928 2.38 ENSRNOT00000012082
F-box protein 46
chr16_+_39145230 2.38 ENSRNOT00000092942
ADAM metallopeptidase domain 21
chr5_+_142986526 2.34 ENSRNOT00000012811
R-spondin 1
chr10_+_87759769 2.32 ENSRNOT00000017378
ENSRNOT00000046526
keratin associated protein 9-1
chr1_+_225163391 2.31 ENSRNOT00000027305
eukaryotic translation elongation factor 1 gamma
chr8_-_17524839 2.30 ENSRNOT00000081679
N-acetylated alpha-linked acidic dipeptidase 2
chr10_-_82117109 2.29 ENSRNOT00000079711
ATP binding cassette subfamily C member 3
chr3_+_48626038 2.29 ENSRNOT00000009697
grancalcin
chr13_-_82295123 2.25 ENSRNOT00000090120
similar to hypothetical protein FLJ10706
chr3_+_93909156 2.24 ENSRNOT00000090365
LIM domain only 2
chr6_-_140880070 2.20 ENSRNOT00000073779
uncharacterized LOC691828
chr12_-_30491102 2.20 ENSRNOT00000001224
sulfatase modifying factor 2
chrX_+_23414354 2.18 ENSRNOT00000031235
claudin 34A
chr6_+_76079880 2.14 ENSRNOT00000009304
similar to 1110008L16Rik protein
chr4_+_22898527 2.09 ENSRNOT00000072455
ENSRNOT00000076123
DBF4 zinc finger
chr2_+_30664639 2.08 ENSRNOT00000076372
ENSRNOT00000076294
ENSRNOT00000076434
ENSRNOT00000076484
TATA-box binding protein associated factor 9
chr2_-_27343998 2.08 ENSRNOT00000091418
DNA polymerase kappa
chr1_+_61382118 2.05 ENSRNOT00000050119
zinc finger protein 52
chr3_-_57607683 2.03 ENSRNOT00000093222
ENSRNOT00000058524
methyltransferase like 8
chr14_-_21709084 2.01 ENSRNOT00000087477
submaxillary gland androgen regulated protein 3B
chr5_+_144106802 2.00 ENSRNOT00000035637
ENSRNOT00000079779
LSM10, U7 small nuclear RNA associated
chr14_+_23405717 2.00 ENSRNOT00000029805
transmembrane protease, serine 11C
chr4_-_155690869 1.98 ENSRNOT00000012216
complement C3a receptor 1
chr1_-_78180216 1.97 ENSRNOT00000071576
complement component 5a receptor 2
chr4_-_80395502 1.94 ENSRNOT00000014437
neuropeptide VF precursor
chr15_-_32925673 1.93 ENSRNOT00000081045
olfactory receptor 1646
chr10_-_34242985 1.88 ENSRNOT00000046438
similar to novel protein
chr8_+_104106740 1.87 ENSRNOT00000015015
transcription factor Dp-2
chr3_-_80933283 1.86 ENSRNOT00000007771
cAMP responsive element binding protein 3-like 1
chr12_+_41316764 1.85 ENSRNOT00000090867
2'-5'-oligoadenylate synthetase 3
chr7_+_16404755 1.83 ENSRNOT00000044977
olfactory receptor 6C70-like
chr16_+_29674793 1.80 ENSRNOT00000059724
annexin A10
chr7_-_139649286 1.78 ENSRNOT00000080056
SUMO1/sentrin specific peptidase 1
chr3_+_102456938 1.75 ENSRNOT00000051827
olfactory receptor 748
chr1_-_227965386 1.74 ENSRNOT00000028491
membrane spanning 4-domains A2
chr15_-_36798814 1.73 ENSRNOT00000065764
centromere protein J
chr14_-_21758788 1.68 ENSRNOT00000038520
RIKEN cDNA 2310003L06 gene
chr5_-_162751128 1.68 ENSRNOT00000068281
similar to novel protein similar to esterases
chrX_-_64715823 1.66 ENSRNOT00000076297
ankyrin repeat and SOCS box-containing 12
chr4_-_66955732 1.66 ENSRNOT00000084282
lysine (K)-specific demethylase 7A
chr8_+_127702534 1.66 ENSRNOT00000075793
CTD small phosphatase like
chr11_+_81358592 1.66 ENSRNOT00000002487
replication factor C subunit 4
chr3_-_431933 1.63 ENSRNOT00000033653
speckle type BTB/POZ protein like
chr8_-_84835060 1.63 ENSRNOT00000007867
leucine rich repeat containing 1
chrX_+_124631881 1.63 ENSRNOT00000009329
ATPase Na+/K+ transporting family member beta 4
chr4_-_162649618 1.62 ENSRNOT00000050861
killer cell lectin-like receptor, subfamily A, member 5
chr2_-_192481273 1.62 ENSRNOT00000012135
small proline-rich protein 2D
chr1_-_90057923 1.55 ENSRNOT00000028674
programmed cell death 2-like
chr1_-_126211439 1.54 ENSRNOT00000014988
tight junction protein 1
chr2_+_30664217 1.53 ENSRNOT00000076786
adenylate kinase 6
chr15_+_39779648 1.51 ENSRNOT00000084505
calcium binding protein 39-like
chr4_+_163349125 1.50 ENSRNOT00000084823
killer cell lectin-like receptor, family E, member 1
chr17_-_10001901 1.43 ENSRNOT00000082836
fibroblast growth factor receptor 4
chr3_-_147263275 1.42 ENSRNOT00000029620
proteasome inhibitor subunit 1
chr8_-_128026841 1.41 ENSRNOT00000018341
myeloid differentiation primary response 88
chr8_+_40707068 1.38 ENSRNOT00000074529
olfactory receptor 1214
chr4_+_156752082 1.38 ENSRNOT00000084588
ENSRNOT00000068407
CD163 molecule
chr3_-_102484517 1.37 ENSRNOT00000006522
olfactory receptor 750
chr3_-_165700489 1.35 ENSRNOT00000017008
zinc finger protein 93
chr17_+_84881414 1.33 ENSRNOT00000034157
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10
chr17_+_45467015 1.32 ENSRNOT00000081408
glutathione peroxidase 5
chr1_-_755645 1.31 ENSRNOT00000073546
vomeronasal 2 receptor, 6
chr7_-_143497108 1.29 ENSRNOT00000048613
keratin 76
chr3_+_160092975 1.28 ENSRNOT00000080707
cAMP-dependent protein kinase inhibitor gamma
chr2_-_198706428 1.28 ENSRNOT00000085006
RNA polymerase III subunit G like
chr8_+_61671513 1.28 ENSRNOT00000091128
protein tyrosine phosphatase, non-receptor type 9
chr4_+_149908375 1.27 ENSRNOT00000019504
uncharacterized LOC100909657
chr4_-_170186942 1.25 ENSRNOT00000082235
WW domain-binding protein 11-like 1
chr2_+_88217188 1.25 ENSRNOT00000014267
carbonic anhydrase I
chr20_-_13994794 1.24 ENSRNOT00000093466
gamma-glutamyltransferase 5
chr1_-_167698263 1.24 ENSRNOT00000093046
tripartite motif-containing 21
chr4_+_70614524 1.22 ENSRNOT00000041100
protease, serine 3
chr10_+_95770154 1.21 ENSRNOT00000030300
helicase with zinc finger
chr1_+_169115981 1.21 ENSRNOT00000067478
olfactory receptor 135
chr3_+_63379031 1.19 ENSRNOT00000068199
oxysterol binding protein-like 6
chr4_-_59014416 1.18 ENSRNOT00000049811
similar to 60S ribosomal protein L38
chr1_+_227892956 1.17 ENSRNOT00000028483

chr15_+_108318664 1.17 ENSRNOT00000057469
UBA domain containing 2
chr14_-_24123253 1.13 ENSRNOT00000002743
transmembrane protease, serine 11B
chr15_-_36451720 1.13 ENSRNOT00000075752
similar to granzyme C
chr6_-_105214329 1.09 ENSRNOT00000008954
COX16, cytochrome c oxidase assembly homolog
chr8_-_53277859 1.09 ENSRNOT00000009574
5-hydroxytryptamine receptor 3B
chr9_-_14550625 1.06 ENSRNOT00000078227
O-acyl-ADP-ribose deacylase 1
chr7_+_18068060 1.05 ENSRNOT00000065474
vomeronasal 1 receptor 107
chr1_-_238376841 1.04 ENSRNOT00000076393
transmembrane channel-like 1
chr15_-_35394792 1.04 ENSRNOT00000028058
granzyme C
chr19_-_56799445 1.04 ENSRNOT00000024491
similar to TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr4_-_148437961 1.02 ENSRNOT00000082907
arachidonate 5-lipoxygenase
chr7_+_122203532 1.02 ENSRNOT00000025382
small G protein signaling modulator 3
chr4_-_164536556 1.01 ENSRNOT00000087796
Ly49 inhibitory receptor 2
chr10_+_106812739 1.01 ENSRNOT00000074225
synaptogyrin 2
chr3_+_112346627 1.00 ENSRNOT00000074392
synaptosomal-associated protein 23
chr5_+_124476168 0.99 ENSRNOT00000077754
similar to novel protein
chr5_+_163867961 0.97 ENSRNOT00000081495

chr9_+_95161157 0.96 ENSRNOT00000071200
UDP glucuronosyltransferase family 1 member A5

Network of associatons between targets according to the STRING database.

First level regulatory network of Isl2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.6 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
1.3 6.4 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627) negative regulation of T-helper 2 cell differentiation(GO:0045629)
1.2 3.7 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
1.0 3.1 GO:0016107 sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488)
1.0 5.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.9 2.8 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.9 7.1 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.9 9.6 GO:0006228 UTP biosynthetic process(GO:0006228)
0.8 3.0 GO:0051542 negative regulation of iron ion transmembrane transport(GO:0034760) elastin biosynthetic process(GO:0051542) regulation of cytochrome-c oxidase activity(GO:1904959)
0.7 2.8 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.7 2.0 GO:0002462 tolerance induction to nonself antigen(GO:0002462)
0.7 2.6 GO:1902623 negative regulation of neutrophil migration(GO:1902623)
0.6 9.8 GO:1902358 oxalate transport(GO:0019532) sulfate transmembrane transport(GO:1902358)
0.5 2.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.5 10.5 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.5 6.0 GO:0006108 malate metabolic process(GO:0006108)
0.5 1.5 GO:0002856 stimulatory C-type lectin receptor signaling pathway(GO:0002223) negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859)
0.5 5.8 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.5 1.4 GO:0072566 chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.5 9.6 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.4 1.7 GO:0061511 centriole elongation(GO:0061511)
0.4 3.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.4 2.3 GO:0042908 xenobiotic transport(GO:0042908)
0.4 4.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.4 1.4 GO:0007037 vacuolar phosphate transport(GO:0007037) positive regulation of parathyroid hormone secretion(GO:2000830)
0.3 1.7 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.3 2.9 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.3 8.6 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.3 3.5 GO:0000733 DNA strand renaturation(GO:0000733)
0.3 6.0 GO:0010818 T cell chemotaxis(GO:0010818) induction of positive chemotaxis(GO:0050930) positive regulation of myoblast fusion(GO:1901741)
0.3 1.9 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.3 2.1 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.3 0.9 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.3 2.1 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.3 2.3 GO:2000254 regulation of male germ cell proliferation(GO:2000254)
0.3 0.5 GO:0016095 polyprenol catabolic process(GO:0016095)
0.3 1.0 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
0.3 1.8 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.2 4.6 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.2 0.7 GO:0032672 regulation of interleukin-3 production(GO:0032672) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.2 0.7 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.2 1.5 GO:0071000 response to magnetism(GO:0071000)
0.2 2.8 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.2 1.0 GO:0060005 vestibular reflex(GO:0060005)
0.2 1.7 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 0.8 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.2 1.9 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.2 2.0 GO:0097264 self proteolysis(GO:0097264)
0.2 2.3 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.2 1.9 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.2 2.8 GO:0036035 osteoclast development(GO:0036035)
0.2 2.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.2 1.7 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.2 1.9 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.2 1.2 GO:0006751 glutathione catabolic process(GO:0006751)
0.2 1.2 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.2 0.8 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 0.9 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 1.0 GO:0048227 regulation of Rab protein signal transduction(GO:0032483) plasma membrane to endosome transport(GO:0048227)
0.1 1.0 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 4.8 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.1 0.7 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 2.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.4 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.1 0.5 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.3 GO:0089709 histidine transport(GO:0015817) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 1.0 GO:0052697 xenobiotic glucuronidation(GO:0052697)
0.1 1.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 1.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 4.3 GO:0014037 Schwann cell differentiation(GO:0014037)
0.1 3.3 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.1 0.5 GO:0061364 negative regulation of negative chemotaxis(GO:0050925) apoptotic process involved in luteolysis(GO:0061364)
0.1 2.4 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 0.9 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.8 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.4 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 1.3 GO:0048733 sebaceous gland development(GO:0048733)
0.1 0.4 GO:0043313 regulation of neutrophil degranulation(GO:0043313)
0.1 0.5 GO:0043587 tongue morphogenesis(GO:0043587)
0.1 0.2 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.6 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 4.0 GO:0048662 negative regulation of smooth muscle cell proliferation(GO:0048662)
0.1 0.5 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 2.0 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 0.8 GO:0001886 endothelial cell morphogenesis(GO:0001886) positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 0.9 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 1.3 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.6 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.1 0.5 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.2 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.1 10.2 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.1 0.8 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.8 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 0.3 GO:0060721 regulation of spongiotrophoblast cell proliferation(GO:0060721) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.8 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.4 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.2 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 2.7 GO:0007595 lactation(GO:0007595)
0.0 0.3 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.0 0.2 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 1.3 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.8 GO:0031572 mitotic G2 DNA damage checkpoint(GO:0007095) G2 DNA damage checkpoint(GO:0031572) mitotic G2/M transition checkpoint(GO:0044818)
0.0 1.4 GO:0018149 peptide cross-linking(GO:0018149)
0.0 1.7 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.1 GO:1902961 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.8 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.0 1.4 GO:1901799 negative regulation of proteasomal protein catabolic process(GO:1901799)
0.0 2.1 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 0.2 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 1.4 GO:0006414 translational elongation(GO:0006414)
0.0 0.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 1.0 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.6 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 3.2 GO:0008584 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 1.0 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.4 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.7 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.5 GO:0030101 natural killer cell activation(GO:0030101)
0.0 0.8 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.8 GO:0007569 cell aging(GO:0007569)
0.0 0.5 GO:0033003 regulation of mast cell activation(GO:0033003)
0.0 1.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.5 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.6 GO:1990090 cellular response to nerve growth factor stimulus(GO:1990090)
0.0 0.9 GO:0098869 cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.7 GO:0010043 response to zinc ion(GO:0010043)
0.0 4.3 GO:0007283 spermatogenesis(GO:0007283)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 9.6 GO:0097598 outer dynein arm(GO:0036157) sperm cytoplasmic droplet(GO:0097598)
1.4 8.6 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
1.3 5.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.7 6.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.6 10.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.3 2.1 GO:0000125 PCAF complex(GO:0000125)
0.3 4.8 GO:0060091 kinocilium(GO:0060091)
0.3 5.8 GO:0001520 outer dense fiber(GO:0001520)
0.3 2.0 GO:0005683 U7 snRNP(GO:0005683)
0.3 1.7 GO:0005663 DNA replication factor C complex(GO:0005663)
0.3 5.8 GO:0002080 acrosomal membrane(GO:0002080)
0.2 3.7 GO:1990023 mitotic spindle pole(GO:0097431) mitotic spindle midzone(GO:1990023)
0.2 1.6 GO:0097524 sperm plasma membrane(GO:0097524)
0.2 6.6 GO:0005605 basal lamina(GO:0005605)
0.2 0.8 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.2 2.8 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 1.1 GO:0001740 Barr body(GO:0001740)
0.1 1.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.5 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 1.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 2.8 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 1.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 1.0 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.6 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 3.3 GO:0005771 multivesicular body(GO:0005771)
0.1 1.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.7 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 1.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.0 GO:0042581 specific granule(GO:0042581)
0.1 0.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.2 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.1 1.4 GO:0001533 cornified envelope(GO:0001533)
0.0 3.5 GO:0045095 keratin filament(GO:0045095)
0.0 5.1 GO:0005814 centriole(GO:0005814)
0.0 2.1 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 2.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 1.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 6.0 GO:0030018 Z disc(GO:0030018)
0.0 2.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.9 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.0 GO:0005921 gap junction(GO:0005921)
0.0 4.6 GO:0031514 motile cilium(GO:0031514)
0.0 1.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.5 GO:0030673 axolemma(GO:0030673)
0.0 1.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 3.7 GO:0030027 lamellipodium(GO:0030027)
0.0 4.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.9 GO:0043296 apical junction complex(GO:0043296)
0.0 1.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 5.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.4 GO:0000502 proteasome complex(GO:0000502)
0.0 3.8 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.1 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 3.6 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.4 GO:0004556 alpha-amylase activity(GO:0004556)
1.3 6.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
1.2 6.0 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
1.0 3.1 GO:0045550 geranylgeranyl reductase activity(GO:0045550)
1.0 8.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.9 7.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.8 2.5 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.8 9.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.7 10.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.7 2.7 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.7 2.0 GO:0071209 histone pre-mRNA DCP binding(GO:0071208) U7 snRNA binding(GO:0071209)
0.7 2.0 GO:0001847 opsonin receptor activity(GO:0001847)
0.7 9.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.6 5.8 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.6 3.0 GO:0032767 copper-exporting ATPase activity(GO:0004008) copper-dependent protein binding(GO:0032767) copper-transporting ATPase activity(GO:0043682)
0.6 3.5 GO:0009378 four-way junction helicase activity(GO:0009378)
0.5 9.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.5 3.3 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.5 1.4 GO:0070976 TIR domain binding(GO:0070976)
0.4 2.2 GO:0004140 adenylate kinase activity(GO:0004017) dephospho-CoA kinase activity(GO:0004140)
0.4 1.7 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.4 2.4 GO:0019767 IgE receptor activity(GO:0019767)
0.4 2.8 GO:0004065 arylsulfatase activity(GO:0004065)
0.4 1.8 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.3 1.0 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.3 0.8 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.3 2.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.3 2.8 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.3 3.3 GO:0019841 retinol binding(GO:0019841)
0.3 2.3 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.3 2.5 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 3.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 0.9 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.2 2.0 GO:0004875 complement receptor activity(GO:0004875)
0.2 2.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.2 1.2 GO:0003840 gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.2 9.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 1.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2 4.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 1.5 GO:0071253 connexin binding(GO:0071253)
0.2 1.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 1.3 GO:0004064 arylesterase activity(GO:0004064)
0.2 11.9 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2 0.5 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.2 0.8 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 0.6 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.5 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 0.6 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 2.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 1.0 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 7.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.3 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290)
0.1 2.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.8 GO:0030274 LIM domain binding(GO:0030274)
0.1 2.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.4 GO:0070628 proteasome binding(GO:0070628)
0.1 0.4 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.1 7.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 2.2 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 0.5 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 17.1 GO:0030246 carbohydrate binding(GO:0030246)
0.1 2.3 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 4.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 1.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 9.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.8 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 5.6 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.3 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.0 0.2 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.5 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 1.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 1.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.1 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.9 GO:0046332 SMAD binding(GO:0046332)
0.0 0.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0008527 taste receptor activity(GO:0008527)
0.0 1.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 3.3 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 2.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 4.2 GO:0005525 GTP binding(GO:0005525)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.2 3.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 6.0 PID IL23 PATHWAY IL23-mediated signaling events
0.1 4.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 2.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 1.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 2.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.1 PID MYC PATHWAY C-MYC pathway
0.1 1.4 PID FGF PATHWAY FGF signaling pathway
0.1 4.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.5 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 7.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 7.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.7 PID E2F PATHWAY E2F transcription factor network
0.0 0.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.8 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.0 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.4 8.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 4.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 2.9 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 2.0 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 1.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 2.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 4.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 1.1 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.1 4.6 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.1 2.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 4.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.5 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 2.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 3.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 10.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 2.1 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 4.0 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 1.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.9 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 5.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 3.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 3.2 REACTOME TRANSLATION Genes involved in Translation
0.0 1.1 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.0 0.4 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes