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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Irx5

Z-value: 0.90

Motif logo

Transcription factors associated with Irx5

Gene Symbol Gene ID Gene Info
ENSRNOG00000011180 iroquois homeobox 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Irx5rn6_v1_chr19_+_16415636_16415636-0.181.3e-03Click!

Activity profile of Irx5 motif

Sorted Z-values of Irx5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_189328246 42.63 ENSRNOT00000084260
acyl-CoA synthetase medium-chain family member 1
chr7_-_123655896 42.09 ENSRNOT00000012413
cytochrome P450, family 2, subfamily d, polypeptide 2
chr12_-_29743705 28.63 ENSRNOT00000001185
calneuron 1
chr2_-_235161263 28.39 ENSRNOT00000080235
uncharacterized LOC103691699
chr1_-_259287684 28.35 ENSRNOT00000054724
cytochrome P450, family 2, subfamily c, polypeptide 22
chr13_-_56763981 27.76 ENSRNOT00000087916
complement factor H-related protein B
chr3_+_40038336 27.64 ENSRNOT00000048804
polypeptide N-acetylgalactosaminyltransferase 13
chr7_-_123621102 27.22 ENSRNOT00000046024
cytochrome P450, family 2, subfamily d, polypeptide 5
chr7_-_123630045 25.65 ENSRNOT00000050002
cytochrome P450, family 2, subfamily d, polypeptide 1
chr7_-_123638702 24.55 ENSRNOT00000082473
ENSRNOT00000044470
ENSRNOT00000092017
cytochrome P450, family 2, subfamily d, polypeptide 1
chr5_-_166116516 22.69 ENSRNOT00000079919
ENSRNOT00000080888
kinesin family member 1B
chr17_-_10439691 20.74 ENSRNOT00000024151
cadherin-related family member 2
chr8_+_33514042 20.15 ENSRNOT00000081614
ENSRNOT00000081525
potassium voltage-gated channel subfamily J member 1
chr3_+_134440195 19.41 ENSRNOT00000072928

chr16_+_50181316 17.51 ENSRNOT00000077662
coagulation factor XI
chr2_+_251200686 15.98 ENSRNOT00000019210
collagen type XXIV alpha 1 chain
chr1_+_80141630 15.04 ENSRNOT00000029552
optic atrophy 3
chr4_-_52350624 14.68 ENSRNOT00000060476
transmembrane protein 229A
chr7_+_26522314 13.16 ENSRNOT00000011572
solute carrier family 41 member 2
chr8_+_5676665 12.14 ENSRNOT00000012310
matrix metallopeptidase 3
chr14_-_46153212 11.82 ENSRNOT00000079269
NACHT and WD repeat domain containing 2
chr8_+_57936650 11.62 ENSRNOT00000089686
exophilin 5
chr2_+_228544418 10.09 ENSRNOT00000013030
translocation associated membrane protein 1-like 1
chr3_+_112916217 9.56 ENSRNOT00000030065
transmembrane protein 62
chr1_+_268189277 9.14 ENSRNOT00000065001
sortilin-related VPS10 domain containing receptor 3
chr7_+_139685573 8.41 ENSRNOT00000088376
phosphofructokinase, muscle
chr6_+_107999846 8.25 ENSRNOT00000058095
prostaglandin reductase 2
chr1_-_100969560 8.06 ENSRNOT00000035908
carnitine palmitoyltransferase 1c
chr1_+_261497059 7.60 ENSRNOT00000020390
golgin A7 family, member B
chr8_+_42511520 7.59 ENSRNOT00000042974
olfactory receptor 1259
chr16_+_25773602 7.42 ENSRNOT00000047750
glyceraldehyde-3-phosphate dehydrogenase, pseudogene 2
chr20_-_422464 7.39 ENSRNOT00000051646
olfactory receptor 1673
chr9_+_65013862 7.18 ENSRNOT00000092906
ENSRNOT00000081146
aldehyde oxidase 3
chr13_+_57243877 7.11 ENSRNOT00000083693
potassium sodium-activated channel subfamily T member 2
chr10_-_12818137 7.08 ENSRNOT00000060972
olfactory receptor 1382
chr7_-_124999137 7.05 ENSRNOT00000039228
patatin-like phospholipase domain containing 5
chr2_+_208738132 6.64 ENSRNOT00000023972

chr18_-_28017925 6.60 ENSRNOT00000075420
leucine rich repeat transmembrane neuronal 2
chr4_+_29978739 6.58 ENSRNOT00000011756
protein phosphatase 1, regulatory subunit 9A
chr2_+_104744461 6.57 ENSRNOT00000016083
ENSRNOT00000082627
ceruloplasmin
chr5_+_122390522 6.47 ENSRNOT00000064567
SH3-domain GRB2-like (endophilin) interacting protein 1
chr10_-_36336628 6.38 ENSRNOT00000030035
zinc finger protein 879
chr11_-_45688560 6.01 ENSRNOT00000081508
olfactory receptor 1536
chr10_+_55997614 5.85 ENSRNOT00000013071
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr3_+_77018186 5.57 ENSRNOT00000074443
olfactory receptor 646
chr17_+_76359022 5.36 ENSRNOT00000039621
ENSRNOT00000092481
Sec61 translocon alpha 2 subunit
chr4_-_142970245 5.13 ENSRNOT00000067815

chr3_-_78571715 4.83 ENSRNOT00000044992
olfactory receptor 712
chrM_+_3904 4.83 ENSRNOT00000040993
mitochondrially encoded NADH dehydrogenase 2
chr3_-_103217528 4.76 ENSRNOT00000074456
olfactory receptor 784
chr4_+_21462779 4.70 ENSRNOT00000089747
glutamate metabotropic receptor 3
chr1_-_276228574 4.65 ENSRNOT00000021746
guanylate cyclase 2G
chr4_-_103403976 4.58 ENSRNOT00000088153

chrX_-_119162518 4.48 ENSRNOT00000073176
ubiquitin-conjugating enzyme E2 W
chr1_+_68528976 4.46 ENSRNOT00000072292
vomeronasal 1 receptor 27
chr10_-_52290657 4.32 ENSRNOT00000005293
mitogen activated protein kinase kinase 4
chr1_+_75194565 4.28 ENSRNOT00000050604
vomeronasal 1 receptor 60
chr1_-_60634546 4.17 ENSRNOT00000051451
vomeronasal 1 receptor 15
chrX_-_37003642 4.09 ENSRNOT00000040770
ENSRNOT00000058834
ENSRNOT00000058833
adhesion G protein-coupled receptor G2
chr1_+_168196862 4.06 ENSRNOT00000021006
olfactory receptor 74
chr1_+_229349133 4.02 ENSRNOT00000075498
serine protease inhibitor Kazal-type 14-like
chr1_+_201901342 4.01 ENSRNOT00000036657
similar to synaptonemal complex protein 3
chr2_-_259382765 3.99 ENSRNOT00000091407
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr10_-_12674077 3.85 ENSRNOT00000041353
olfactory receptor 1376
chr19_+_51317425 3.83 ENSRNOT00000019298
cadherin 13
chr1_+_157920786 3.77 ENSRNOT00000014284
family with sequence similarity 181, member B
chr3_-_78595778 3.73 ENSRNOT00000084255
olfactory receptor 715
chr1_-_230687157 3.71 ENSRNOT00000048193
olfactory receptor 380
chr1_+_167786337 3.67 ENSRNOT00000024945
olfactory receptor 48
chr2_-_149754776 3.63 ENSRNOT00000035057
similar to hypothetical protein C130079G13
chr5_+_69305190 3.55 ENSRNOT00000074390
olfactory receptor 13C3-like
chr3_-_2845593 3.54 ENSRNOT00000067479
transmembrane protein 141
chr3_-_73543088 3.51 ENSRNOT00000012912
olfactory receptor 485
chr9_-_92524739 3.38 ENSRNOT00000089889
solute carrier family 16, member 14
chr4_+_72603242 3.34 ENSRNOT00000007229
olfactory receptor 818
chr1_-_103811148 3.27 ENSRNOT00000030162
MAS-related G protein-coupled receptor, member X2-like
chr7_-_6803318 3.21 ENSRNOT00000084203
olfactory receptor 954
chr3_-_78790691 3.08 ENSRNOT00000008750
olfactory receptor 724
chr3_+_93968855 2.99 ENSRNOT00000014478
F-box protein 3
chrX_+_159560292 2.98 ENSRNOT00000087250
vestigial like family member 1
chr7_+_9279620 2.79 ENSRNOT00000011225
olfactory receptor 1064
chr8_-_114013623 2.78 ENSRNOT00000018175
ATPase secretory pathway Ca2+ transporting 1
chr3_-_103128243 2.72 ENSRNOT00000046310
olfactory receptor 779
chr1_+_168341595 2.60 ENSRNOT00000048411
olfactory receptor 84
chr1_-_168611670 2.59 ENSRNOT00000021273
olfactory receptor 106
chr7_-_5106708 2.49 ENSRNOT00000046001
olfactory receptor 892
chr7_-_15856676 2.48 ENSRNOT00000086553

chr3_-_78409263 2.44 ENSRNOT00000041001
olfactory receptor 704
chr5_-_69277783 2.36 ENSRNOT00000046638
olfactory receptor 847
chr1_-_149175205 2.29 ENSRNOT00000089091
ENSRNOT00000045611
ENSRNOT00000089015
vomeronasal 2 receptor, 42
chr1_+_225690756 2.25 ENSRNOT00000027498
prostatic steroid-binding protein C2
chr3_-_73580594 2.22 ENSRNOT00000012929
olfactory receptor 488
chr3_-_78663607 2.04 ENSRNOT00000073134
olfactory receptor 718
chr3_-_77792014 1.99 ENSRNOT00000091085
olfactory receptor 671
chrX_-_152110010 1.98 ENSRNOT00000044666
melanoma antigen family A, 5-like
chr1_-_147272006 1.95 ENSRNOT00000086862

chr1_+_60117804 1.90 ENSRNOT00000080437
vomeronasal 1 receptor 8
chr3_+_75768699 1.79 ENSRNOT00000071912

chr17_-_42817037 1.73 ENSRNOT00000023166
Prolactin family 3, subfamily c, member 1
chr3_-_78886096 1.72 ENSRNOT00000008864
olfactory receptor 729
chr7_+_47928060 1.71 ENSRNOT00000005740
coiled-coil domain containing 59
chr4_+_87312766 1.69 ENSRNOT00000052126
vomeronasal 1 receptor 71
chr20_-_11498277 1.69 ENSRNOT00000046763

chr3_+_75834770 1.68 ENSRNOT00000043371
olfactory receptor 582
chr1_+_72230038 1.58 ENSRNOT00000058997
vomeronasal 1 receptor 38
chr4_+_157057601 1.54 ENSRNOT00000040592
Zinc finger protein 42-like
chr7_-_3707226 1.43 ENSRNOT00000064380
olfactory receptor 879
chr3_-_78555530 1.42 ENSRNOT00000089672
olfactory receptor 711
chr5_+_108935189 1.31 ENSRNOT00000071169

chr1_+_168403613 1.30 ENSRNOT00000079028
olfactory receptor 88
chr1_+_168411463 1.28 ENSRNOT00000072397
olfactory receptor 89
chr1_+_230604386 1.25 ENSRNOT00000040608
olfactory receptor 375
chr3_+_75437833 1.24 ENSRNOT00000042246
olfactory receptor 561
chr3_-_76696107 1.23 ENSRNOT00000044692
olfactory receptor 629
chr11_-_43594659 1.22 ENSRNOT00000086976
olfactory receptor 1555
chr11_-_70211701 1.05 ENSRNOT00000076114
mucin 13, cell surface associated
chr20_+_734642 0.99 ENSRNOT00000073543
olfactory receptor 1688
chr7_-_47928674 0.96 ENSRNOT00000038144
methyltransferase like 25
chr10_+_61160125 0.95 ENSRNOT00000074715
olfactory receptor 1519
chr18_-_26658892 0.91 ENSRNOT00000038247
erythrocyte membrane protein band 4.1 like 4A
chr1_-_169770188 0.88 ENSRNOT00000072602
olfactory receptor 165
chr3_-_74790822 0.86 ENSRNOT00000045888
olfactory receptor 8K3-like
chr8_+_25246292 0.86 ENSRNOT00000021625
neuropeptide S receptor 1
chr8_-_50246656 0.78 ENSRNOT00000024240
SID1 transmembrane family, member 2
chr1_-_168015148 0.72 ENSRNOT00000020691
olfactory receptor 50
chr1_-_66688422 0.66 ENSRNOT00000082786
vomeronasal 1 receptor 57
chr1_-_60281386 0.63 ENSRNOT00000092184
vomeronasal 1 receptor 10
chr8_-_117237229 0.63 ENSRNOT00000071381
kelch domain containing 8B
chr1_-_172030164 0.53 ENSRNOT00000026807
ovochymase 2
chr17_+_79749747 0.48 ENSRNOT00000081743

chr2_-_220838905 0.46 ENSRNOT00000078914

chr7_-_143167772 0.37 ENSRNOT00000011374
keratin 85
chr2_+_194557986 0.29 ENSRNOT00000070843
TD and POZ domain-containing protein 2-like
chr14_+_1318157 0.25 ENSRNOT00000061889
vomeronasal 2 receptor, 67
chr3_+_76768051 0.19 ENSRNOT00000047382
olfactory receptor 634
chr1_-_67284864 0.14 ENSRNOT00000082908
similar to zinc finger and SCAN domain containing 4
chr3_-_74906989 0.13 ENSRNOT00000071001
olfactory receptor 545
chr1_+_75748916 0.12 ENSRNOT00000083154
ENSRNOT00000089836
binder of sperm protein homolog 1
chr8_+_19888667 0.09 ENSRNOT00000078593
zinc finger protein 317
chr1_-_168310071 0.06 ENSRNOT00000044675
olfactory receptor 82
chr3_+_75809445 0.05 ENSRNOT00000049950
olfactory receptor 581
chr1_+_169741497 0.02 ENSRNOT00000072865
olfactory receptor 164

Network of associatons between targets according to the STRING database.

First level regulatory network of Irx5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.7 20.2 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
4.5 22.7 GO:0019520 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
4.2 50.2 GO:0042738 exogenous drug catabolic process(GO:0042738)
4.1 20.7 GO:1904970 brush border assembly(GO:1904970)
2.5 17.5 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
2.1 8.4 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
1.7 12.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
1.6 97.7 GO:0019369 arachidonic acid metabolic process(GO:0019369)
1.4 7.2 GO:0009115 xanthine catabolic process(GO:0009115)
1.2 11.6 GO:0071985 multivesicular body sorting pathway(GO:0071985)
1.1 6.6 GO:1900272 negative regulation of long-term synaptic potentiation(GO:1900272)
1.1 4.3 GO:0072709 cellular response to sorbitol(GO:0072709)
1.0 7.6 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.9 2.8 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.9 6.5 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.8 6.6 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.8 6.6 GO:0015679 plasma membrane copper ion transport(GO:0015679)
0.5 9.1 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.5 8.1 GO:0009437 carnitine metabolic process(GO:0009437)
0.5 15.0 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.5 27.6 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.5 3.8 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.5 42.6 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.4 4.7 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.3 8.3 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.2 4.0 GO:0006677 glycosylceramide metabolic process(GO:0006677)
0.2 4.5 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.2 1.5 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.2 4.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 0.9 GO:2000293 negative regulation of eating behavior(GO:1903999) regulation of defecation(GO:2000292) negative regulation of defecation(GO:2000293)
0.2 7.0 GO:0019433 triglyceride catabolic process(GO:0019433)
0.2 3.5 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.8 GO:0033227 dsRNA transport(GO:0033227)
0.1 4.7 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.1 17.7 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.1 102.8 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 1.0 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 9.1 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 7.1 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 13.1 GO:0070838 divalent metal ion transport(GO:0070838)
0.0 4.1 GO:0007286 spermatid development(GO:0007286)
0.0 14.1 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.9 20.7 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
2.8 8.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
2.5 22.7 GO:0071821 FANCM-MHF complex(GO:0071821)
1.6 6.6 GO:1990761 growth cone lamellipodium(GO:1990761)
1.5 5.9 GO:0031417 NatC complex(GO:0031417)
1.0 28.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.7 7.6 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.4 6.5 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.4 49.2 GO:0072562 blood microparticle(GO:0072562)
0.2 8.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 4.7 GO:0097449 astrocyte projection(GO:0097449)
0.2 4.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 147.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 4.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 7.0 GO:0005811 lipid particle(GO:0005811)
0.1 34.4 GO:0000139 Golgi membrane(GO:0000139)
0.1 4.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 7.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 21.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 15.7 GO:0060076 excitatory synapse(GO:0060076)
0.0 3.8 GO:0005901 caveola(GO:0005901)
0.0 185.6 GO:0016021 integral component of membrane(GO:0016021)
0.0 11.6 GO:0005768 endosome(GO:0005768)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 42.6 GO:0003996 acyl-CoA ligase activity(GO:0003996)
5.0 20.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
3.8 22.7 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
3.6 147.9 GO:0070330 aromatase activity(GO:0070330)
2.8 8.3 GO:0047522 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
2.5 27.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
2.1 8.4 GO:0003872 6-phosphofructokinase activity(GO:0003872)
2.0 8.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
1.6 4.7 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
1.5 17.5 GO:0070008 serine-type exopeptidase activity(GO:0070008)
1.4 7.2 GO:0016726 aldehyde oxidase activity(GO:0004031) xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
1.1 6.6 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
1.0 3.8 GO:0055100 adiponectin binding(GO:0055100)
0.8 4.0 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.5 6.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.4 4.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.4 7.0 GO:0004806 triglyceride lipase activity(GO:0004806)
0.3 2.8 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.3 7.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 16.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 6.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 7.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 4.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 4.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 0.8 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 15.0 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 12.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 102.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 5.4 GO:0043022 ribosome binding(GO:0043022)
0.1 0.9 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 13.1 GO:0072509 divalent inorganic cation transmembrane transporter activity(GO:0072509)
0.1 11.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 6.5 GO:0017124 SH3 domain binding(GO:0017124)
0.0 2.2 GO:0005496 steroid binding(GO:0005496)
0.0 4.5 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 11.9 GO:0005509 calcium ion binding(GO:0005509)
0.0 9.9 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 3.0 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 1.7 GO:0005179 hormone activity(GO:0005179)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 16.0 NABA COLLAGENS Genes encoding collagen proteins
0.3 4.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 12.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 8.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 8.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 6.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 17.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.7 19.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.6 32.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.5 20.2 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.5 42.6 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.3 16.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 4.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 8.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 5.3 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.2 4.3 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 3.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 5.4 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.1 9.1 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 2.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 3.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation