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GSE53960: rat RNA-Seq transcriptomic Bodymap
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Results for Irx5
Z-value: 0.90
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Transcription factors associated with Irx5
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Irx5 | rn6_v1_chr19_+_16415636_16415636 | -0.18 | 1.3e-03 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_+_189328246 Show fit | 42.63 |
ENSRNOT00000084260
|
acyl-CoA synthetase medium-chain family member 1 |
|
| chr7_-_123655896 Show fit | 42.09 |
ENSRNOT00000012413
|
cytochrome P450, family 2, subfamily d, polypeptide 2 |
|
| chr12_-_29743705 Show fit | 28.63 |
ENSRNOT00000001185
|
calneuron 1 |
|
| chr2_-_235161263 Show fit | 28.39 |
ENSRNOT00000080235
|
uncharacterized LOC103691699 |
|
| chr1_-_259287684 Show fit | 28.35 |
ENSRNOT00000054724
|
cytochrome P450, family 2, subfamily c, polypeptide 22 |
|
| chr13_-_56763981 Show fit | 27.76 |
ENSRNOT00000087916
|
complement factor H-related protein B |
|
| chr3_+_40038336 Show fit | 27.64 |
ENSRNOT00000048804
|
polypeptide N-acetylgalactosaminyltransferase 13 |
|
| chr7_-_123621102 Show fit | 27.22 |
ENSRNOT00000046024
|
cytochrome P450, family 2, subfamily d, polypeptide 5 |
|
| chr7_-_123630045 Show fit | 25.65 |
ENSRNOT00000050002
|
cytochrome P450, family 2, subfamily d, polypeptide 1 |
|
| chr7_-_123638702 Show fit | 24.55 |
ENSRNOT00000082473
ENSRNOT00000044470 ENSRNOT00000092017 |
cytochrome P450, family 2, subfamily d, polypeptide 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Irx5
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 102.8 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 1.6 | 97.7 | GO:0019369 | arachidonic acid metabolic process(GO:0019369) |
| 4.2 | 50.2 | GO:0042738 | exogenous drug catabolic process(GO:0042738) |
| 0.5 | 42.6 | GO:0035383 | acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383) |
| 0.5 | 27.6 | GO:0006493 | protein O-linked glycosylation(GO:0006493) |
| 4.5 | 22.7 | GO:0019520 | aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521) |
| 4.1 | 20.7 | GO:1904970 | brush border assembly(GO:1904970) |
| 6.7 | 20.2 | GO:1901979 | regulation of inward rectifier potassium channel activity(GO:1901979) |
| 0.1 | 17.7 | GO:0002244 | hematopoietic progenitor cell differentiation(GO:0002244) |
| 2.5 | 17.5 | GO:0051919 | positive regulation of fibrinolysis(GO:0051919) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 185.6 | GO:0016021 | integral component of membrane(GO:0016021) |
| 0.2 | 147.9 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 0.4 | 49.2 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.1 | 34.4 | GO:0000139 | Golgi membrane(GO:0000139) |
| 1.0 | 28.6 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 2.5 | 22.7 | GO:0071821 | FANCM-MHF complex(GO:0071821) |
| 0.1 | 21.3 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 6.9 | 20.7 | GO:0089717 | spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717) |
| 0.1 | 15.7 | GO:0060076 | excitatory synapse(GO:0060076) |
| 0.0 | 11.6 | GO:0005768 | endosome(GO:0005768) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.6 | 147.9 | GO:0070330 | aromatase activity(GO:0070330) |
| 0.1 | 102.8 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 5.3 | 42.6 | GO:0003996 | acyl-CoA ligase activity(GO:0003996) |
| 2.5 | 27.6 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 3.8 | 22.7 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
| 5.0 | 20.2 | GO:0015272 | ATP-activated inward rectifier potassium channel activity(GO:0015272) |
| 1.5 | 17.5 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
| 0.2 | 16.0 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 15.0 | GO:0016503 | pheromone receptor activity(GO:0016503) |
| 0.1 | 13.1 | GO:0072509 | divalent inorganic cation transmembrane transporter activity(GO:0072509) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 16.0 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.2 | 12.1 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.1 | 8.4 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 8.1 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.1 | 6.6 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.3 | 4.3 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 42.6 | REACTOME PHASE II CONJUGATION | Genes involved in Phase II conjugation |
| 0.6 | 32.7 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.5 | 20.2 | REACTOME INWARDLY RECTIFYING K CHANNELS | Genes involved in Inwardly rectifying K+ channels |
| 0.7 | 19.7 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.8 | 17.5 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
| 0.3 | 16.0 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.1 | 9.1 | REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 0.2 | 8.4 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.1 | 5.4 | REACTOME ER PHAGOSOME PATHWAY | Genes involved in ER-Phagosome pathway |
| 0.2 | 5.3 | REACTOME EXTRACELLULAR MATRIX ORGANIZATION | Genes involved in Extracellular matrix organization |