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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Hsfy2

Z-value: 0.77

Motif logo

Transcription factors associated with Hsfy2

Gene Symbol Gene ID Gene Info
ENSRNOG00000038569 heat shock transcription factor, Y linked 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hsfy2rn6_v1_chr9_-_63291350_63291350-0.261.8e-06Click!

Activity profile of Hsfy2 motif

Sorted Z-values of Hsfy2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_24456976 42.76 ENSRNOT00000004900
uncoupling protein 1
chr3_-_91217491 18.16 ENSRNOT00000006115
recombination activating 1
chr13_-_91981432 14.97 ENSRNOT00000004637

chr2_+_200785507 11.95 ENSRNOT00000046942
hydroxyacid oxidase 2
chr16_-_74122889 11.75 ENSRNOT00000025763
plasminogen activator, tissue type
chr8_+_49282460 11.52 ENSRNOT00000021488
CD3d molecule
chr2_+_60337667 11.29 ENSRNOT00000024035
alanine-glyoxylate aminotransferase 2
chr4_-_145390447 11.14 ENSRNOT00000091965
ENSRNOT00000012136
cell death-inducing DFFA-like effector c
chr5_-_159962676 10.78 ENSRNOT00000013550
chloride voltage-gated channel Kb
chr17_-_9762813 10.76 ENSRNOT00000033749
solute carrier family 34 member 1
chr20_-_31598118 10.53 ENSRNOT00000046537
collagen type XIII alpha 1 chain
chr10_-_47059216 10.08 ENSRNOT00000007092
serine hydroxymethyltransferase 1
chr20_-_31597830 10.00 ENSRNOT00000085877
collagen type XIII alpha 1 chain
chrX_-_1848904 9.76 ENSRNOT00000010984
regucalcin
chr4_+_71621729 9.49 ENSRNOT00000022275
glutathione S-transferase kappa 1
chr1_+_150797084 9.38 ENSRNOT00000018990
NADPH oxidase 4
chr9_-_15410943 9.15 ENSRNOT00000074217
cyclin D3
chr5_-_159962218 8.78 ENSRNOT00000050729
chloride voltage-gated channel Kb
chr2_-_235161263 8.68 ENSRNOT00000080235
uncharacterized LOC103691699
chr18_+_38292701 8.36 ENSRNOT00000037796
secretoglobin, family 3A, member 2
chr9_-_20154077 8.12 ENSRNOT00000082904
adhesion G protein-coupled receptor F5
chr4_-_176679815 8.07 ENSRNOT00000090122
glycogen synthase 2
chr8_-_107952530 7.79 ENSRNOT00000052043
claudin 18
chr9_+_61692154 7.58 ENSRNOT00000082300
heat shock protein family E member 1
chr14_+_91783514 7.50 ENSRNOT00000080753
IKAROS family zinc finger 1
chr1_-_22625204 7.33 ENSRNOT00000021694
vanin 1
chr1_-_47307488 7.33 ENSRNOT00000090033
ezrin
chr1_+_141821916 7.15 ENSRNOT00000071574
enoyl-CoA hydratase, short chain 1
chr13_-_104080631 7.05 ENSRNOT00000032865
lysophospholipase-like 1
chr19_+_55982740 6.91 ENSRNOT00000021397
dipeptidase 1 (renal)
chr10_-_31493419 6.89 ENSRNOT00000009211
IL2-inducible T-cell kinase
chr10_+_71202456 6.88 ENSRNOT00000076893
HNF1 homeobox B
chr16_-_49003246 6.82 ENSRNOT00000089501
acyl-CoA synthetase long-chain family member 1
chr4_+_145594575 6.79 ENSRNOT00000029819
interleukin-1 receptor-associated kinase 2
chr7_-_143793774 6.76 ENSRNOT00000079678
cysteine sulfinic acid decarboxylase
chr9_+_112293388 6.74 ENSRNOT00000020767
mannosidase, alpha, class 2A, member 1
chr4_+_70828894 6.62 ENSRNOT00000064892
T cell receptor beta, constant 2
chr12_+_40466495 6.56 ENSRNOT00000001816
aldehyde dehydrogenase 2 family (mitochondrial)
chr1_+_189364288 6.51 ENSRNOT00000080338
acyl-CoA synthetase medium-chain family member 1
chr20_-_4070721 6.40 ENSRNOT00000000523
RT1 class II, locus Ba
chr10_-_15235740 6.28 ENSRNOT00000027170
MAPK regulated co-repressor interacting protein 2
chr1_-_216663720 6.06 ENSRNOT00000078944
ENSRNOT00000077409
cyclin-dependent kinase inhibitor 1C
chrX_+_156319687 5.76 ENSRNOT00000091147
ENSRNOT00000079378
family with sequence similarity 3, member A
chr9_+_16924520 5.75 ENSRNOT00000025094
solute carrier family 22 member 7
chr6_+_107531528 5.70 ENSRNOT00000077555
acyl-CoA thioesterase 3
chr4_-_115015965 5.68 ENSRNOT00000014603
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr16_+_54319377 5.67 ENSRNOT00000090266
microtubule associated tumor suppressor 1
chr1_+_125229469 5.65 ENSRNOT00000021884
methylmalonyl CoA epimerase
chr1_+_199682688 5.65 ENSRNOT00000027265
ENSRNOT00000080872
solute carrier family 5 member 2
chr10_-_94576512 5.57 ENSRNOT00000035474
intercellular adhesion molecule 2
chr3_+_129462738 5.52 ENSRNOT00000077755

chr10_-_15465404 5.42 ENSRNOT00000077826
ENSRNOT00000027593
2,4-dienoyl-CoA reductase 2
chr1_+_191829555 5.30 ENSRNOT00000067138
sodium channel epithelial 1 beta subunit
chr7_-_143793970 5.29 ENSRNOT00000016205
cysteine sulfinic acid decarboxylase
chr2_+_26240385 5.28 ENSRNOT00000024292
coagulation factor II (thrombin) receptor-like 2
chr5_+_34007920 5.24 ENSRNOT00000009611
alpha tocopherol transfer protein
chr14_+_85113578 5.24 ENSRNOT00000011158
nipsnap homolog 1
chr19_-_11302938 5.20 ENSRNOT00000038212

chr10_+_86399827 5.18 ENSRNOT00000009299
growth factor receptor bound protein 7
chr5_+_4982348 5.17 ENSRNOT00000010369
lactamase, beta 2
chr1_+_104576589 5.06 ENSRNOT00000046529
neuron navigator 2
chr7_-_130405347 4.99 ENSRNOT00000013985
carnitine palmitoyltransferase 1B
chr2_-_23256158 4.96 ENSRNOT00000015336
betaine-homocysteine S-methyltransferase
chr1_-_226935689 4.95 ENSRNOT00000038807
transmembrane protein 109
chr15_+_32811135 4.85 ENSRNOT00000067689

chr3_-_67668772 4.77 ENSRNOT00000010247
frizzled-related protein
chr16_+_54291251 4.72 ENSRNOT00000079006
microtubule associated tumor suppressor 1
chr4_+_71650575 4.62 ENSRNOT00000033775
transmembrane protein 139
chr12_+_52452273 4.61 ENSRNOT00000056680
ENSRNOT00000088381
peroxisomal membrane protein 2
chr16_+_50022998 4.57 ENSRNOT00000087986
toll-like receptor 3
chr20_+_13760810 4.51 ENSRNOT00000081140
ENSRNOT00000080203
glutathione S-transferase, theta 2
chr3_+_72329967 4.50 ENSRNOT00000090256
solute carrier family 43, member 3
chr18_-_51651267 4.48 ENSRNOT00000020325
aldehyde dehydrogenase 7 family, member A1
chr8_-_52937972 4.42 ENSRNOT00000007789
nicotinamide N-methyltransferase
chr11_+_47243342 4.42 ENSRNOT00000041116
NFKB inhibitor zeta
chrX_-_13601069 4.40 ENSRNOT00000004686
ornithine carbamoyltransferase
chr14_+_71542057 4.34 ENSRNOT00000082592
ENSRNOT00000083701
ENSRNOT00000084322
prominin 1
chr5_+_126670825 4.32 ENSRNOT00000012201
cytochrome b5 reductase-like
chr3_-_79728879 4.29 ENSRNOT00000012425
NADH dehydrogenase (ubiquinone) Fe-S protein 3
chr17_-_43689311 4.16 ENSRNOT00000028779
histone cluster 1, H2bc-like 1
chr13_-_70573572 4.10 ENSRNOT00000092339
laminin subunit gamma 2
chr1_-_61872975 4.00 ENSRNOT00000078809

chr1_-_207811008 3.92 ENSRNOT00000080506
clarin 3
chr8_-_62424303 3.91 ENSRNOT00000091223
c-src tyrosine kinase
chr4_+_96562725 3.90 ENSRNOT00000009094
neuron-derived neurotrophic factor
chr19_-_57614558 3.90 ENSRNOT00000025948
similar to RIKEN cDNA 0610039J04
chr7_-_3386522 3.88 ENSRNOT00000010760
methyltransferase like 7B
chr5_+_141491223 3.88 ENSRNOT00000034839
rhomboid like 2
chr1_-_226887156 3.84 ENSRNOT00000054809
ENSRNOT00000028347
Cd6 molecule
chr2_-_47096961 3.83 ENSRNOT00000077401
integrin alpha 2
chr10_-_70337532 3.82 ENSRNOT00000055963
schlafen family member 13
chr7_-_11319516 3.77 ENSRNOT00000027784
amyloid beta precursor protein binding family A member 3
chr2_+_84275884 3.75 ENSRNOT00000014439
death-associated protein
chr2_-_117666683 3.70 ENSRNOT00000015479

chr5_-_172307431 3.67 ENSRNOT00000018453
family with sequence similarity 213, member B
chr10_+_35133252 3.65 ENSRNOT00000051916
secretoglobin, family 3A, member 1
chr7_-_63578490 3.65 ENSRNOT00000007295
Ras association domain family member 3
chr2_+_128461224 3.65 ENSRNOT00000018872
jade family PHD finger 1
chr4_+_109477920 3.58 ENSRNOT00000008468
regenerating islet-derived 3 alpha
chr1_+_228142778 3.57 ENSRNOT00000028517
mitochondrial ribosomal protein L16
chr3_-_150108898 3.51 ENSRNOT00000022914
peroxisomal membrane protein 4
chr4_+_153874852 3.50 ENSRNOT00000079744
solute carrier family 6 member 13
chrM_+_7006 3.46 ENSRNOT00000043693
mitochondrially encoded cytochrome c oxidase II
chr4_+_120672152 3.45 ENSRNOT00000077231
monoglyceride lipase
chr6_+_43884678 3.43 ENSRNOT00000091551
ribonucleotide reductase regulatory subunit M2
chr10_-_78156477 3.36 ENSRNOT00000083009
syntaxin binding protein 4
chr20_+_48504264 3.35 ENSRNOT00000087740
cell division cycle 40
chr1_-_76780230 3.32 ENSRNOT00000002046
alcohol sulfotransferase-like
chr16_-_68968248 3.31 ENSRNOT00000016885
eukaryotic translation initiation factor 4E binding protein 1
chr5_-_4975436 3.29 ENSRNOT00000062006
XK related 9
chr1_+_83653234 3.18 ENSRNOT00000085008
ENSRNOT00000084230
ENSRNOT00000090071
cytochrome P450, family 2, subfamily a, polypeptide 1
chr17_+_60059949 3.14 ENSRNOT00000025458
membrane palmitoylated protein 7
chr4_+_155321553 3.08 ENSRNOT00000089614
microfibrillar associated protein 5
chr1_-_85317968 3.04 ENSRNOT00000026891
glia maturation factor, gamma
chrX_-_74968405 3.04 ENSRNOT00000035653
similar to KIAA2022 protein
chr6_+_99402360 3.02 ENSRNOT00000078498
zinc finger and BTB domain containing 1
chr6_-_26486695 3.01 ENSRNOT00000073236
keratinocyte associated protein 3
chr10_-_76039964 3.00 ENSRNOT00000003164
musashi RNA-binding protein 2
chr9_+_9988055 2.93 ENSRNOT00000086575
ENSRNOT00000073000
solute carrier family 25 member 23
chrX_+_1787266 2.91 ENSRNOT00000011183
NADH:ubiquinone oxidoreductase subunit B11
chr2_+_127845034 2.90 ENSRNOT00000044804
La ribonucleoprotein domain family, member 1B
chr2_-_192960294 2.90 ENSRNOT00000012420
late cornified envelope protein 5A-like
chr15_+_56757315 2.88 ENSRNOT00000078013
esterase D
chr1_-_263885169 2.87 ENSRNOT00000030782
conserved helix-loop-helix ubiquitous kinase
chr17_+_72218769 2.87 ENSRNOT00000041346
ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
chr3_+_175708519 2.87 ENSRNOT00000085983

chr9_-_49950093 2.86 ENSRNOT00000023014
four and a half LIM domains 2
chr5_-_133786403 2.82 ENSRNOT00000081051
ENSRNOT00000010318
cytidine/uridine monophosphate kinase 1
chr12_-_22138382 2.81 ENSRNOT00000001899
leucine rich repeats and calponin homology domain containing 4
chr8_-_87158368 2.80 ENSRNOT00000077071
collagen type XII alpha 1 chain
chr8_-_28044876 2.77 ENSRNOT00000072152
acyl-CoA dehydrogenase family, member 8
chr15_+_32276947 2.76 ENSRNOT00000068094

chr14_+_13192347 2.75 ENSRNOT00000000092
anthrax toxin receptor 2
chr16_-_49820235 2.74 ENSRNOT00000029628
sorbin and SH3 domain containing 2
chr1_-_77865870 2.74 ENSRNOT00000017353
EH-domain containing 2
chr10_-_109747987 2.72 ENSRNOT00000054958
prolyl 4-hydroxylase subunit beta
chrX_-_72077590 2.72 ENSRNOT00000004278
ribosomal protein S4, X-linked
chrX_-_128268285 2.71 ENSRNOT00000009755
ENSRNOT00000081880
THO complex 2
chrX_-_84768463 2.69 ENSRNOT00000088570
CHM, Rab escort protein 1
chr17_+_90696019 2.67 ENSRNOT00000003438
G protein-coupled receptor 137B
chr5_+_135997052 2.66 ENSRNOT00000024921
Tctex1 domain containing 4
chr16_-_37177033 2.66 ENSRNOT00000014015
F-box protein 8
chr4_-_156427755 2.62 ENSRNOT00000085675
ENSRNOT00000014030
peroxisomal targeting signal 1 receptor-like
chr4_-_157008947 2.59 ENSRNOT00000073341
peroxisomal biogenesis factor 5
chr10_+_88764732 2.57 ENSRNOT00000026662
signal transducer and activator of transcription 5A
chr2_+_104854572 2.56 ENSRNOT00000064828
ENSRNOT00000090912
helicase-like transcription factor
chrX_+_140175861 2.55 ENSRNOT00000071222
coiled-coil domain containing 160
chr14_+_2613406 2.51 ENSRNOT00000000083
transmembrane p24 trafficking protein 5
chr6_+_64649194 2.50 ENSRNOT00000039776

chr19_+_10596960 2.49 ENSRNOT00000021769
cytokine induced apoptosis inhibitor 1
chr9_-_10054359 2.48 ENSRNOT00000072001
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr20_+_3167079 2.46 ENSRNOT00000001035
RT1 class Ib, locus N3
chr10_+_40438356 2.45 ENSRNOT00000078910
GM2 ganglioside activator
chr1_+_166893734 2.44 ENSRNOT00000026702
paired-like homeobox 2a
chr8_-_23099042 2.41 ENSRNOT00000019115
ECSIT signalling integrator
chr1_+_259926537 2.41 ENSRNOT00000073537
cyclin J
chr2_-_192671059 2.40 ENSRNOT00000012174
small proline-rich protein 1A
chr12_-_37480297 2.39 ENSRNOT00000001397
transmembrane p24 trafficking protein 2
chr9_-_99651813 2.36 ENSRNOT00000022089
NADH:ubiquinone oxidoreductase subunit A10
chr1_+_36320461 2.34 ENSRNOT00000023659
steroid 5 alpha-reductase 1
chr18_+_32273770 2.32 ENSRNOT00000087408
fibroblast growth factor 1
chr7_-_126701872 2.31 ENSRNOT00000041057
polycystin (PKD) family receptor for egg jelly
chr11_+_33863500 2.31 ENSRNOT00000072384
carbonyl reductase [NADPH] 1-like
chr9_+_95285592 2.29 ENSRNOT00000063853
UDP glucuronosyltransferase family 1 member A5
chr2_-_53140637 2.28 ENSRNOT00000060492
coiled-coil domain containing 152
chr11_-_89239798 2.27 ENSRNOT00000089517
scaffolding protein involved in DNA repair
chr19_-_10620671 2.27 ENSRNOT00000021842
C-C motif chemokine ligand 17
chr17_+_72160735 2.26 ENSRNOT00000038817
inter-alpha-trypsin inhibitor heavy chain 2
chr1_+_100755682 2.26 ENSRNOT00000035748
vaccinia related kinase 3
chr10_-_87300728 2.25 ENSRNOT00000036023
ENSRNOT00000081709
keratin 10
chr8_-_55037604 2.25 ENSRNOT00000059169
succinate dehydrogenase complex subunit D
chr12_-_11215649 2.23 ENSRNOT00000042474
ENSRNOT00000076369
cleavage and polyadenylation specific factor 4
chr2_-_193136520 2.22 ENSRNOT00000042142
keratinocyte proline-rich protein
chr1_+_57692836 2.20 ENSRNOT00000083968
ENSRNOT00000019358
chromodomain helicase DNA binding protein 1
chr14_+_84447885 2.20 ENSRNOT00000009150
GATS protein-like 3
chr15_+_105640097 2.19 ENSRNOT00000014300
muscleblind-like splicing regulator 2
chrX_+_123770337 2.19 ENSRNOT00000092554
NFKB activating protein
chr8_-_33463467 2.17 ENSRNOT00000041038
potassium voltage-gated channel subfamily J member 5
chr1_-_100669684 2.15 ENSRNOT00000091760
myosin heavy chain 14
chr9_-_61033553 2.15 ENSRNOT00000002864
ENSRNOT00000082681
general transcription factor IIIC subunit 3
chr15_+_31446983 2.14 ENSRNOT00000089506

chr19_+_38768467 2.14 ENSRNOT00000027346
cadherin 1
chr10_-_56267213 2.14 ENSRNOT00000017201
mannose-P-dolichol utilization defect 1
chr11_-_82938357 2.12 ENSRNOT00000035945
mitogen-activated protein kinase kinase kinase 13
chr2_+_34546988 2.11 ENSRNOT00000072577
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr10_-_57275708 2.11 ENSRNOT00000005370
profilin 1
chr10_+_10530365 2.10 ENSRNOT00000003843
eukaryotic elongation factor 2 lysine methyltransferase
chrX_-_77061604 2.10 ENSRNOT00000083643
ENSRNOT00000089386
magnesium transporter 1
chr14_+_22251499 2.10 ENSRNOT00000087991
ENSRNOT00000002705
UDP glucuronosyltransferase 2 family, polypeptide A1
chr1_+_257076221 2.10 ENSRNOT00000044895
solute carrier family 35, member G1
chr1_-_168471161 2.06 ENSRNOT00000055227
olfactory receptor 94
chr20_+_3875706 2.04 ENSRNOT00000036900
RT1 class II, locus Ha
chr19_-_44101365 2.02 ENSRNOT00000082182
transmembrane protein 170A
chr2_+_44664124 2.00 ENSRNOT00000066098
phospholipid phosphatase 1
chr8_+_132441285 1.99 ENSRNOT00000087488
ENSRNOT00000068233
leucyl-tRNA synthetase 2
chr10_+_96639924 1.99 ENSRNOT00000004756
apolipoprotein H
chr17_+_35435079 1.98 ENSRNOT00000074800
exocyst complex component 2
chr4_-_78074906 1.97 ENSRNOT00000080654
zinc finger protein 467
chr1_+_219000844 1.97 ENSRNOT00000022486
lysine methyltransferase 5B
chr7_-_117680004 1.96 ENSRNOT00000040422
solute carrier family 39 member 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Hsfy2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 18.2 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
4.0 12.1 GO:0042412 taurine biosynthetic process(GO:0042412)
4.0 12.0 GO:0018924 mandelate metabolic process(GO:0018924)
3.8 11.3 GO:0019265 glycine biosynthetic process, by transamination of glyoxylate(GO:0019265)
3.6 10.8 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
3.4 10.1 GO:0009177 pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
3.3 9.8 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
2.9 11.8 GO:0060279 positive regulation of ovulation(GO:0060279)
2.6 5.2 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210)
2.6 39.1 GO:0002024 diet induced thermogenesis(GO:0002024)
2.6 7.8 GO:2001205 negative regulation of osteoclast development(GO:2001205)
2.4 19.6 GO:0030321 transepithelial chloride transport(GO:0030321)
2.3 6.9 GO:1901146 mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
1.9 5.7 GO:0032789 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
1.9 7.5 GO:0045658 regulation of neutrophil differentiation(GO:0045658)
1.8 7.3 GO:1902896 terminal web assembly(GO:1902896)
1.8 11.0 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
1.7 5.0 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
1.5 4.6 GO:0006227 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
1.5 4.5 GO:0009751 response to salicylic acid(GO:0009751)
1.3 5.1 GO:0021564 vagus nerve development(GO:0021564)
1.1 4.6 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
1.1 4.3 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
1.0 6.1 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
1.0 3.0 GO:0002572 pro-T cell differentiation(GO:0002572)
1.0 6.8 GO:0034201 response to oleic acid(GO:0034201)
1.0 2.9 GO:1902741 response to acetate(GO:0010034) type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
1.0 4.8 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.9 2.7 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.9 16.3 GO:0050667 homocysteine metabolic process(GO:0050667)
0.9 8.1 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.9 4.4 GO:0006526 arginine biosynthetic process(GO:0006526)
0.9 2.6 GO:1901093 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.9 3.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.9 6.9 GO:0001865 NK T cell differentiation(GO:0001865)
0.8 11.5 GO:0045059 positive thymic T cell selection(GO:0045059)
0.8 2.4 GO:0021558 trochlear nerve development(GO:0021558)
0.8 3.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.8 2.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.7 9.1 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.7 10.5 GO:0034389 lipid particle organization(GO:0034389)
0.7 2.0 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.6 2.6 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.6 2.6 GO:0060375 development of secondary male sexual characteristics(GO:0046544) regulation of mast cell differentiation(GO:0060375)
0.6 1.9 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.6 3.8 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.6 20.5 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.6 6.7 GO:0006013 mannose metabolic process(GO:0006013)
0.6 7.3 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.6 3.0 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.6 1.8 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.6 3.0 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.6 6.6 GO:0006068 ethanol catabolic process(GO:0006068)
0.6 2.3 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.6 4.5 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.6 3.3 GO:1990928 response to amino acid starvation(GO:1990928)
0.5 2.1 GO:0060066 oviduct development(GO:0060066)
0.5 1.6 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.5 1.6 GO:0007356 thorax and anterior abdomen determination(GO:0007356)
0.5 1.5 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.5 2.0 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.5 6.9 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.5 5.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.5 3.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.5 2.9 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.5 1.9 GO:0072249 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.5 5.7 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.5 3.2 GO:0009804 coumarin metabolic process(GO:0009804)
0.5 2.7 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.4 1.3 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.4 5.4 GO:0052695 cellular glucuronidation(GO:0052695)
0.4 5.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.4 4.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.4 5.7 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.4 6.8 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.4 5.2 GO:0034063 stress granule assembly(GO:0034063)
0.4 1.2 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.4 1.2 GO:0019303 D-ribose catabolic process(GO:0019303)
0.4 2.0 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.4 0.8 GO:0061198 fungiform papilla morphogenesis(GO:0061197) fungiform papilla formation(GO:0061198)
0.4 6.4 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.4 1.5 GO:1900063 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651) regulation of peroxisome organization(GO:1900063)
0.4 1.1 GO:0060846 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) blood vessel lumenization(GO:0072554) blood vessel endothelial cell fate specification(GO:0097101) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.4 2.2 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914) potassium ion import across plasma membrane(GO:1990573)
0.3 3.4 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.3 10.4 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.3 0.7 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.3 3.6 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.3 4.3 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.3 2.3 GO:0072757 cellular response to camptothecin(GO:0072757)
0.3 3.8 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.3 1.6 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.3 2.7 GO:0018344 protein geranylgeranylation(GO:0018344)
0.3 4.4 GO:0001887 selenium compound metabolic process(GO:0001887)
0.3 1.2 GO:1902606 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.3 1.4 GO:0006564 L-serine biosynthetic process(GO:0006564) threonine metabolic process(GO:0006566)
0.3 1.2 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.3 2.0 GO:0001927 exocyst assembly(GO:0001927)
0.3 2.0 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.3 2.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.3 1.4 GO:0019563 glycerol catabolic process(GO:0019563)
0.3 2.4 GO:0006689 ganglioside catabolic process(GO:0006689)
0.3 2.4 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.3 5.7 GO:0035337 fatty-acyl-CoA metabolic process(GO:0035337)
0.3 1.9 GO:0010912 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.3 2.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.3 0.5 GO:0033084 regulation of immature T cell proliferation in thymus(GO:0033084) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.3 0.8 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.3 3.5 GO:0015693 magnesium ion transport(GO:0015693)
0.3 1.0 GO:0060178 regulation of exocyst localization(GO:0060178)
0.2 1.5 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.2 2.7 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.2 1.0 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.2 1.0 GO:0002337 B-1 B cell differentiation(GO:0001923) B-1a B cell differentiation(GO:0002337)
0.2 3.7 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.2 3.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.2 2.9 GO:0060347 heart trabecula formation(GO:0060347)
0.2 3.0 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.2 1.6 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.2 5.3 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313)
0.2 7.5 GO:0018149 peptide cross-linking(GO:0018149)
0.2 4.8 GO:0070831 basement membrane assembly(GO:0070831)
0.2 4.3 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.2 1.3 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.2 1.3 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.2 2.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.2 9.5 GO:0006749 glutathione metabolic process(GO:0006749)
0.2 1.4 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.2 1.8 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.2 12.1 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.2 0.4 GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
0.2 2.3 GO:0042448 progesterone metabolic process(GO:0042448)
0.2 1.0 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.2 1.7 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.2 2.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 0.7 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.2 0.5 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.2 1.1 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.2 5.6 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.2 1.4 GO:0061193 taste bud development(GO:0061193)
0.2 0.5 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.2 3.4 GO:0006301 postreplication repair(GO:0006301)
0.2 1.7 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.2 1.8 GO:0006517 protein deglycosylation(GO:0006517)
0.2 0.8 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.2 0.5 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.2 0.5 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.2 6.1 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.2 1.1 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.2 5.0 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.2 3.1 GO:0097435 fibril organization(GO:0097435)
0.2 2.3 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 3.7 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.1 1.5 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.1 0.3 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.1 2.9 GO:0006119 oxidative phosphorylation(GO:0006119)
0.1 0.9 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 2.5 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 2.0 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 0.4 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 2.5 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 1.4 GO:0016322 neuron remodeling(GO:0016322)
0.1 6.5 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 0.3 GO:0018992 germ-line sex determination(GO:0018992)
0.1 2.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 2.0 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 2.4 GO:0060716 vesicle targeting(GO:0006903) labyrinthine layer blood vessel development(GO:0060716)
0.1 1.8 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 1.1 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.1 0.6 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.4 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 3.8 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.1 0.4 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 2.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.2 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.1 0.3 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 2.7 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 2.2 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 2.2 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 3.8 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 0.6 GO:0071352 cellular response to interleukin-2(GO:0071352)
0.1 0.8 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.1 5.7 GO:0045333 cellular respiration(GO:0045333)
0.1 0.6 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 1.7 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1 3.5 GO:0032543 mitochondrial translation(GO:0032543)
0.1 3.3 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 0.4 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 3.8 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.1 0.3 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.4 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 1.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 1.0 GO:0051597 response to methylmercury(GO:0051597)
0.1 1.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.5 GO:0002934 desmosome organization(GO:0002934)
0.1 2.1 GO:0035987 endodermal cell differentiation(GO:0035987)
0.1 0.2 GO:1903960 negative regulation of anion channel activity(GO:0010360) negative regulation of anion transmembrane transport(GO:1903960)
0.1 3.0 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 4.9 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.3 GO:0051036 regulation of endosome size(GO:0051036)
0.0 0.7 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:0003360 brainstem development(GO:0003360)
0.0 1.1 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 2.1 GO:0035904 aorta development(GO:0035904)
0.0 2.3 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.6 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.2 GO:0032808 lacrimal gland development(GO:0032808)
0.0 1.1 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)
0.0 0.7 GO:0015695 organic cation transport(GO:0015695)
0.0 2.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 1.8 GO:0001707 mesoderm formation(GO:0001707)
0.0 0.3 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.4 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.5 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 0.5 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.2 GO:0086028 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.0 0.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 1.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.3 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.7 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 3.0 GO:0048864 stem cell development(GO:0048864)
0.0 0.5 GO:0031572 mitotic G2 DNA damage checkpoint(GO:0007095) G2 DNA damage checkpoint(GO:0031572)
0.0 0.7 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.9 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.6 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.5 GO:0030220 platelet formation(GO:0030220)
0.0 1.5 GO:0051289 protein homotetramerization(GO:0051289)
0.0 1.8 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.5 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.4 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.2 GO:0009750 response to fructose(GO:0009750)
0.0 0.8 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 1.6 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.8 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 1.2 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 1.6 GO:0017148 negative regulation of translation(GO:0017148)
0.0 18.6 GO:0050911 detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.4 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 1.5 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.1 GO:0042976 activation of Janus kinase activity(GO:0042976)
0.0 0.4 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.5 GO:0043966 histone H3 acetylation(GO:0043966)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.3 GO:0036398 TCR signalosome(GO:0036398) microspike(GO:0044393)
1.4 4.3 GO:0071914 prominosome(GO:0071914)
1.4 11.5 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
1.3 3.8 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
1.3 3.8 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
1.0 4.1 GO:0005607 laminin-2 complex(GO:0005607)
0.9 9.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.9 3.4 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.8 3.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.8 2.3 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) fumarate reductase complex(GO:0045283)
0.7 2.8 GO:0005593 FACIT collagen trimer(GO:0005593)
0.7 2.7 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.7 2.7 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.6 3.0 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.5 2.2 GO:0097513 myosin II filament(GO:0097513)
0.5 8.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.5 7.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.5 5.6 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.4 2.4 GO:0005663 DNA replication factor C complex(GO:0005663)
0.4 5.0 GO:0008385 IkappaB kinase complex(GO:0008385)
0.4 26.3 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.4 2.9 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.3 6.9 GO:0031528 microvillus membrane(GO:0031528)
0.3 1.7 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.3 1.9 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.3 2.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.3 20.5 GO:0005581 collagen trimer(GO:0005581)
0.3 3.1 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.3 7.5 GO:0001533 cornified envelope(GO:0001533)
0.3 1.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.3 1.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3 2.7 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.3 1.9 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.3 2.9 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.3 5.1 GO:0005614 interstitial matrix(GO:0005614)
0.2 2.4 GO:0045179 apical cortex(GO:0045179)
0.2 17.6 GO:0005811 lipid particle(GO:0005811)
0.2 4.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.2 2.1 GO:0016600 flotillin complex(GO:0016600)
0.2 5.0 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 1.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 5.5 GO:0034706 sodium channel complex(GO:0034706)
0.2 11.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.2 10.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 3.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 21.4 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.2 0.6 GO:0034457 Mpp10 complex(GO:0034457)
0.2 8.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 1.1 GO:1990246 uniplex complex(GO:1990246)
0.2 1.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 58.2 GO:0005759 mitochondrial matrix(GO:0005759)
0.2 10.4 GO:0034707 chloride channel complex(GO:0034707)
0.2 8.4 GO:0005844 polysome(GO:0005844)
0.2 1.0 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.2 0.7 GO:0031592 centrosomal corona(GO:0031592)
0.2 0.5 GO:1990879 CST complex(GO:1990879)
0.2 2.0 GO:0042627 chylomicron(GO:0042627)
0.2 13.9 GO:0031526 brush border membrane(GO:0031526)
0.1 0.6 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 41.0 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 2.3 GO:0070852 cell body fiber(GO:0070852)
0.1 0.7 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 6.7 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.5 GO:0005915 zonula adherens(GO:0005915)
0.1 2.4 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.1 1.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 2.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 1.8 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 1.2 GO:0034464 BBSome(GO:0034464)
0.1 0.8 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.7 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.7 GO:0000796 condensin complex(GO:0000796)
0.1 2.2 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.1 4.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 2.9 GO:0031430 M band(GO:0031430)
0.1 0.5 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 2.0 GO:0000145 exocyst(GO:0000145)
0.1 2.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 1.4 GO:0031091 platelet alpha granule(GO:0031091)
0.1 0.3 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 0.2 GO:1990836 lysosomal matrix(GO:1990836)
0.1 1.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 6.1 GO:0072562 blood microparticle(GO:0072562)
0.1 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 2.5 GO:0016235 aggresome(GO:0016235)
0.1 0.6 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 4.9 GO:0000786 nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.1 4.7 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 5.6 GO:0005923 bicellular tight junction(GO:0005923)
0.0 4.1 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 2.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.3 GO:0036449 microtubule minus-end(GO:0036449)
0.0 2.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 12.6 GO:0045177 apical part of cell(GO:0045177)
0.0 5.2 GO:0005770 late endosome(GO:0005770)
0.0 1.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 2.8 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 32.3 GO:0005739 mitochondrion(GO:0005739)
0.0 0.1 GO:0030689 Noc complex(GO:0030689)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 1.5 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 1.5 GO:0030175 filopodium(GO:0030175)
0.0 4.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.7 GO:0015030 Cajal body(GO:0015030)
0.0 5.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 2.9 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0031672 A band(GO:0031672)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
10.7 42.8 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
4.0 12.0 GO:0052852 very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
3.4 10.1 GO:0070905 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) serine binding(GO:0070905)
2.3 6.9 GO:0070573 metallodipeptidase activity(GO:0070573)
2.3 11.3 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
2.2 10.8 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
1.7 6.8 GO:0003987 acetate-CoA ligase activity(GO:0003987)
1.5 4.6 GO:0009041 uridylate kinase activity(GO:0009041) nucleoside phosphate kinase activity(GO:0050145)
1.5 4.4 GO:0098603 selenol Se-methyltransferase activity(GO:0098603)
1.4 5.7 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
1.4 5.4 GO:0019166 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
1.3 6.6 GO:0070404 NADH binding(GO:0070404)
1.2 5.0 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
1.2 8.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
1.1 4.3 GO:0015057 thrombin receptor activity(GO:0015057)
1.0 5.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
1.0 9.4 GO:0016175 NAD(P)H oxidase activity(GO:0016174) superoxide-generating NADPH oxidase activity(GO:0016175)
1.0 19.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
1.0 2.9 GO:0008384 IkappaB kinase activity(GO:0008384)
0.9 7.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.8 6.5 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.8 3.8 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.8 2.3 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.7 2.7 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.7 2.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.7 2.0 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.6 5.0 GO:0008172 S-methyltransferase activity(GO:0008172)
0.6 5.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.6 13.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.6 2.3 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.6 3.5 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.6 3.4 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.6 5.6 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.5 2.2 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.5 2.2 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.5 9.6 GO:0044548 S100 protein binding(GO:0044548)
0.5 1.6 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.5 6.7 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.5 1.5 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.5 2.4 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.5 1.4 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.5 2.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.4 6.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.4 5.8 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.4 10.5 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.4 1.2 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.4 1.1 GO:0015292 uniporter activity(GO:0015292)
0.4 1.1 GO:0034046 poly(G) binding(GO:0034046)
0.4 4.4 GO:0042301 phosphate ion binding(GO:0042301)
0.4 1.4 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.3 3.4 GO:0038064 collagen receptor activity(GO:0038064)
0.3 3.8 GO:0070513 death domain binding(GO:0070513)
0.3 1.7 GO:0004969 histamine receptor activity(GO:0004969)
0.3 2.9 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.3 2.0 GO:0031727 CCR1 chemokine receptor binding(GO:0031726) CCR2 chemokine receptor binding(GO:0031727)
0.3 5.7 GO:0016854 racemase and epimerase activity(GO:0016854)
0.3 4.5 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.3 12.5 GO:0042605 peptide antigen binding(GO:0042605)
0.3 7.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3 8.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.3 3.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.3 3.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 1.1 GO:0033149 FFAT motif binding(GO:0033149)
0.3 1.3 GO:0005550 pheromone binding(GO:0005550)
0.3 0.8 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.2 10.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.2 1.0 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.2 2.4 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 6.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.2 5.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 5.0 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.2 2.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 0.6 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.2 3.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 2.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.2 1.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.2 1.0 GO:1990932 5.8S rRNA binding(GO:1990932)
0.2 3.9 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.2 1.6 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 3.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 0.7 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.2 5.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 2.7 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 1.4 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.2 1.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.2 5.2 GO:0042165 neurotransmitter binding(GO:0042165)
0.2 2.8 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.2 4.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.2 21.8 GO:0004519 endonuclease activity(GO:0004519)
0.2 1.0 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.2 4.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 0.5 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.2 2.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 8.4 GO:0019843 rRNA binding(GO:0019843)
0.2 1.1 GO:0050700 CARD domain binding(GO:0050700)
0.2 24.8 GO:0008201 heparin binding(GO:0008201)
0.2 2.1 GO:0015095 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.0 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 3.3 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.1 1.2 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.7 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 2.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 2.0 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.1 3.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.4 GO:0004359 glutaminase activity(GO:0004359)
0.1 2.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 3.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 1.5 GO:0005522 profilin binding(GO:0005522)
0.1 0.8 GO:0003896 DNA primase activity(GO:0003896)
0.1 3.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 8.2 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.1 0.8 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 5.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 2.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 8.2 GO:0051087 chaperone binding(GO:0051087)
0.1 5.8 GO:0042805 actinin binding(GO:0042805)
0.1 2.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.3 GO:0050693 LBD domain binding(GO:0050693)
0.1 4.7 GO:0000049 tRNA binding(GO:0000049)
0.1 6.2 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 10.5 GO:0051219 phosphoprotein binding(GO:0051219)
0.1 2.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 2.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 0.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.7 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 0.5 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.1 0.7 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.6 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.4 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.3 GO:0016972 thiol oxidase activity(GO:0016972)
0.1 2.4 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.1 0.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 1.4 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 3.7 GO:0016209 antioxidant activity(GO:0016209)
0.1 7.4 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.1 6.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 2.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 2.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.5 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 1.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.5 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.0 0.5 GO:0043047 single-stranded telomeric DNA binding(GO:0043047)
0.0 3.1 GO:0032947 protein complex scaffold(GO:0032947)
0.0 1.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.8 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 1.2 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 1.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 6.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.9 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.4 GO:0005507 copper ion binding(GO:0005507)
0.0 1.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 13.0 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 2.6 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.6 GO:0043236 laminin binding(GO:0043236)
0.0 0.7 GO:0019840 isoprenoid binding(GO:0019840)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 5.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.7 GO:0043130 ubiquitin binding(GO:0043130)
0.0 4.5 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.2 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 2.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.7 GO:0099589 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0 1.3 GO:0001047 core promoter binding(GO:0001047)
0.0 0.8 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 1.2 GO:0005178 integrin binding(GO:0005178)
0.0 1.3 GO:0019905 syntaxin binding(GO:0019905)
0.0 1.4 GO:0008565 protein transporter activity(GO:0008565)
0.0 17.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.3 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 14.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.6 17.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.4 21.9 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.4 24.7 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.4 4.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.4 11.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.4 5.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.3 12.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 1.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2 2.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 6.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 9.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 8.8 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.2 4.8 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.2 8.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2 3.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.2 2.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 5.3 PID INSULIN PATHWAY Insulin Pathway
0.1 3.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 2.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 1.6 PID IL1 PATHWAY IL1-mediated signaling events
0.1 2.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 10.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 1.9 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 2.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 2.5 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 4.2 PID NOTCH PATHWAY Notch signaling pathway
0.1 3.9 PID E2F PATHWAY E2F transcription factor network
0.1 0.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 2.3 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 2.3 PID FGF PATHWAY FGF signaling pathway
0.1 2.4 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.3 PID P73PATHWAY p73 transcription factor network
0.0 1.5 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 1.3 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.7 PID AURORA B PATHWAY Aurora B signaling
0.0 0.7 PID BMP PATHWAY BMP receptor signaling
0.0 0.2 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.4 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 11.5 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
1.0 3.9 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.9 12.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.9 11.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.8 7.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.8 6.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.7 58.3 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.7 6.8 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.6 6.8 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.5 15.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.5 5.8 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.4 8.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.4 24.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.4 8.1 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.3 7.0 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.3 9.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.3 5.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.3 3.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 5.0 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.2 5.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.2 7.3 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.2 4.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 3.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 9.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.2 3.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 2.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 1.5 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.2 8.0 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.2 1.0 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.2 10.1 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.2 2.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.2 2.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.2 10.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 2.4 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1 2.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 0.9 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 3.3 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 6.6 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.1 4.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 1.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.0 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 2.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.8 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 4.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 2.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 3.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 7.3 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.1 3.3 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 5.6 REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.1 2.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 1.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 0.5 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 1.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.4 REACTOME TRAF6 MEDIATED INDUCTION OF NFKB AND MAP KINASES UPON TLR7 8 OR 9 ACTIVATION Genes involved in TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
0.1 7.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 3.8 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.1 1.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 0.9 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1 1.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.7 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.5 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 3.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.1 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 1.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.5 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 2.3 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 0.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis