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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Hoxd12

Z-value: 0.46

Motif logo

Transcription factors associated with Hoxd12

Gene Symbol Gene ID Gene Info
ENSRNOG00000001587 homeo box D12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxd12rn6_v1_chr3_+_61597382_615973820.081.4e-01Click!

Activity profile of Hoxd12 motif

Sorted Z-values of Hoxd12 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_84632817 13.16 ENSRNOT00000076942
muscular LMNA-interacting protein
chr13_+_57243877 12.96 ENSRNOT00000083693
potassium sodium-activated channel subfamily T member 2
chr1_-_93949187 12.86 ENSRNOT00000018956
zinc finger protein 536
chr11_-_59110562 11.72 ENSRNOT00000047907
ENSRNOT00000042024
limbic system-associated membrane protein
chr9_+_73529612 11.04 ENSRNOT00000032430
unc-80 homolog, NALCN activator
chr9_-_60330086 10.79 ENSRNOT00000092162
ENSRNOT00000093630
dynein, axonemal, heavy chain 7
chr13_+_77485113 9.67 ENSRNOT00000080254
tenascin R
chr9_+_118586179 9.36 ENSRNOT00000022351
DLG associated protein 1
chr14_+_12218553 9.33 ENSRNOT00000003237
protein kinase, cGMP-dependent, type II
chr13_-_107886476 8.78 ENSRNOT00000077282
potassium two pore domain channel subfamily K member 2
chr6_+_83421882 8.16 ENSRNOT00000084258
leucine rich repeat and fibronectin type III domain containing 5
chr3_+_48096954 7.82 ENSRNOT00000068238
ENSRNOT00000064344
ENSRNOT00000044638
solute carrier family 4 member 10
chr18_-_8360684 7.64 ENSRNOT00000021170
cadherin 2
chr9_+_95501778 7.23 ENSRNOT00000086805
secreted phosphoprotein 2
chr3_-_67787990 7.17 ENSRNOT00000064851
NCK-associated protein 1
chr10_-_87248572 6.88 ENSRNOT00000066637
ENSRNOT00000085677
keratin 26
chr20_+_5008508 6.59 ENSRNOT00000001153
von Willebrand factor A domain containing 7
chr7_-_93280009 6.53 ENSRNOT00000064877
sterile alpha motif domain containing 12
chr10_+_77537340 6.39 ENSRNOT00000003297
transmembrane protein 100
chr7_-_134722215 6.22 ENSRNOT00000036750
prickle planar cell polarity protein 1
chrX_+_53053609 5.77 ENSRNOT00000058357
dystrophin
chr2_+_60337667 5.67 ENSRNOT00000024035
alanine-glyoxylate aminotransferase 2
chr8_+_87630916 5.57 ENSRNOT00000016428
myosin VI
chr4_+_99063181 5.41 ENSRNOT00000008840
fatty acid binding protein 1
chr15_-_43542939 5.03 ENSRNOT00000012996
dihydropyrimidinase-like 2
chr9_+_20048121 5.00 ENSRNOT00000014791
meprin 1 subunit alpha
chr2_-_250923744 4.64 ENSRNOT00000084996
chloride channel accessory 1
chr2_-_173087648 4.55 ENSRNOT00000091079
IQ motif containing J
chr1_+_143036218 4.33 ENSRNOT00000025797
phosphodiesterase 8A
chr2_+_52431601 4.30 ENSRNOT00000023554
3-hydroxy-3-methylglutaryl-CoA synthase 1
chr17_+_11683862 4.19 ENSRNOT00000024766
msh homeobox 2
chr1_+_148240504 4.18 ENSRNOT00000085373
Cytochrome P450, family 2, subfamily c, polypeptide 7-like
chr8_+_59507990 4.06 ENSRNOT00000018003
hydroxylysine kinase
chr16_+_22361998 4.00 ENSRNOT00000016193
solute carrier family 18 member A1
chr16_+_2706428 3.99 ENSRNOT00000077117
interleukin 17 receptor D
chrM_+_7758 3.76 ENSRNOT00000046201
mitochondrially encoded ATP synthase 8
chr2_+_260249566 3.66 ENSRNOT00000089358
solute carrier family 44, member 5
chrM_+_5323 3.49 ENSRNOT00000050156
mitochondrially encoded cytochrome c oxidase 1
chr13_+_91080341 3.43 ENSRNOT00000000058
C-reactive protein
chr10_+_70262361 3.42 ENSRNOT00000064625
ENSRNOT00000076973
unc-45 myosin chaperone B
chr3_+_140024043 3.41 ENSRNOT00000086409
Ras and Rab interactor 2
chr9_-_30844199 3.37 ENSRNOT00000017169
collagen type XIX alpha 1 chain
chr3_+_14889510 3.16 ENSRNOT00000080760
DAB2 interacting protein
chr1_-_169344306 3.10 ENSRNOT00000022852
ubiquilin-like
chr14_-_16903242 3.03 ENSRNOT00000003001
shroom family member 3
chr14_-_62595854 2.85 ENSRNOT00000003024
Yip1 domain family, member 7
chr4_+_158243086 2.66 ENSRNOT00000032112
anoctamin 2
chr3_+_151126591 2.62 ENSRNOT00000025859
myosin heavy chain 7B
chr20_+_41266566 2.41 ENSRNOT00000000653
fyn-related Src family tyrosine kinase
chr3_-_125017377 2.41 ENSRNOT00000028889
prokineticin receptor 2
chr4_-_176922424 2.39 ENSRNOT00000055540
ATP binding cassette subfamily C member 9
chr8_-_6235967 2.29 ENSRNOT00000068290
hypothetical protein LOC654482
chr18_-_26211445 2.20 ENSRNOT00000027739
neuronal regeneration related protein
chr2_-_57935334 2.19 ENSRNOT00000022319
ENSRNOT00000085599
ENSRNOT00000077790
ENSRNOT00000035821
solute carrier family 1 member 3
chrM_+_7919 2.18 ENSRNOT00000046108
mitochondrially encoded ATP synthase 6
chr14_+_39368530 2.14 ENSRNOT00000084367
cytochrome c oxidase subunit 7B2
chr1_+_14797766 2.03 ENSRNOT00000016048
oligodendrocyte transcription factor 3
chr20_+_5049496 2.02 ENSRNOT00000088251
ENSRNOT00000001118
dimethylarginine dimethylaminohydrolase 2
chr8_+_106816152 1.93 ENSRNOT00000047613
Fas apoptotic inhibitory molecule
chr4_-_51199570 1.85 ENSRNOT00000010788
solute carrier family 13 member 1
chr2_-_173800761 1.84 ENSRNOT00000039524
WD repeat domain 49
chr11_+_46108470 1.80 ENSRNOT00000073467
adhesion G protein-coupled receptor G7
chr7_-_75288365 1.79 ENSRNOT00000036904
ankyrin repeat domain 46
chr7_+_123168811 1.76 ENSRNOT00000007091
cold shock domain containing C2
chr8_+_107229832 1.71 ENSRNOT00000045821
Fas apoptotic inhibitory molecule
chr20_+_1749716 1.70 ENSRNOT00000048856
olfactory receptor 1735
chr3_+_73352352 1.69 ENSRNOT00000012814
olfactory receptor 472
chr3_+_93648343 1.68 ENSRNOT00000091164

chr14_+_104480662 1.66 ENSRNOT00000078710
RAB1A, member RAS oncogene family
chrM_+_8599 1.54 ENSRNOT00000049683
mitochondrially encoded cytochrome C oxidase III
chr18_+_30880020 1.26 ENSRNOT00000060468
protocadherin gamma subfamily B, 5
chr7_+_140829076 1.26 ENSRNOT00000086179
spermatogenesis associated, serine-rich 2
chr1_+_204959174 1.20 ENSRNOT00000023257
zinc finger RANBP2-type containing 1
chr19_-_22194740 1.15 ENSRNOT00000086187
phosphorylase kinase regulatory subunit beta
chr13_+_44615553 1.03 ENSRNOT00000082439
ENSRNOT00000005289
RAB3 GTPase activating protein catalytic subunit 1
chr18_+_14756684 0.99 ENSRNOT00000076085
ENSRNOT00000076129
microtubule-associated protein, RP/EB family, member 2
chr19_-_17045349 0.95 ENSRNOT00000086829
FTO, alpha-ketoglutarate dependent dioxygenase
chr2_+_226563050 0.93 ENSRNOT00000065111
breast cancer anti-estrogen resistance 3
chr5_-_50221095 0.90 ENSRNOT00000012164
similar to hypothetical protein
chr1_-_238376841 0.85 ENSRNOT00000076393
transmembrane channel-like 1
chr5_+_117698764 0.79 ENSRNOT00000011486
angiopoietin-like 3
chr5_+_4373626 0.73 ENSRNOT00000064946
EYA transcriptional coactivator and phosphatase 1
chr11_+_46793777 0.72 ENSRNOT00000002232
adhesion G protein-coupled receptor G7
chr1_-_129217058 0.70 ENSRNOT00000086439
pyroglutamyl-peptidase I-like
chr16_-_16762240 0.69 ENSRNOT00000080746

chr4_+_157726941 0.62 ENSRNOT00000025081
vesicle-associated membrane protein 1
chr1_-_131460473 0.50 ENSRNOT00000084336
nuclear receptor subfamily 2, group F, member 2
chr7_-_145062956 0.35 ENSRNOT00000055274
similar to CDNA sequence BC048502
chr2_+_8732932 0.28 ENSRNOT00000072849
arrestin domain containing 3
chr6_+_52459946 0.20 ENSRNOT00000073277
ENSRNOT00000013474
ataxin 7-like 1
chr13_+_49005405 0.18 ENSRNOT00000092560
ENSRNOT00000076457
LEM domain containing 1
chr9_+_19451630 0.10 ENSRNOT00000065048
ectonucleotide pyrophosphatase/phosphodiesterase 4
chr3_+_154910626 0.09 ENSRNOT00000079515
Ral GTPase activating protein non-catalytic beta subunit
chr1_+_41192824 0.03 ENSRNOT00000082133
estrogen receptor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxd12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.3 GO:2001226 negative regulation of chloride transport(GO:2001226)
2.9 8.8 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
1.9 5.8 GO:0021629 muscle attachment(GO:0016203) olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
1.9 5.7 GO:0019265 glycine biosynthetic process, by transamination of glyoxylate(GO:0019265)
1.8 5.4 GO:0051977 lysophospholipid transport(GO:0051977)
1.6 9.7 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
1.5 7.6 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
1.4 7.2 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
1.4 12.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
1.4 4.2 GO:0035880 embryonic nail plate morphogenesis(GO:0035880) positive regulation of mesenchymal cell apoptotic process(GO:2001055)
1.2 9.4 GO:0070842 aggresome assembly(GO:0070842)
1.1 2.2 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.9 6.4 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.9 19.5 GO:0035641 locomotory exploration behavior(GO:0035641)
0.8 4.0 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.8 3.2 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.7 6.2 GO:0051890 regulation of cardioblast differentiation(GO:0051890)
0.6 10.8 GO:0036159 inner dynein arm assembly(GO:0036159)
0.6 3.4 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.5 2.4 GO:0060327 cytoplasmic actin-based contraction involved in cell motility(GO:0060327)
0.5 13.2 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.4 1.2 GO:1990168 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) protein K33-linked deubiquitination(GO:1990168)
0.3 1.0 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
0.3 2.0 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.3 0.9 GO:0042245 RNA repair(GO:0042245)
0.3 5.0 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.3 3.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.3 0.3 GO:0071877 regulation of adrenergic receptor signaling pathway(GO:0071877) positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.2 5.6 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.2 2.0 GO:0006527 arginine catabolic process(GO:0006527)
0.2 4.3 GO:0009642 response to light intensity(GO:0009642) cellular response to cholesterol(GO:0071397)
0.2 5.9 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 1.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 0.9 GO:0060005 vestibular reflex(GO:0060005)
0.2 0.5 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.2 0.8 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.2 4.2 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 4.3 GO:1903206 negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.1 1.9 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.1 3.6 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.1 0.7 GO:0016576 histone dephosphorylation(GO:0016576) semicircular canal morphogenesis(GO:0048752)
0.1 7.3 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 7.2 GO:0046849 bone remodeling(GO:0046849)
0.1 13.0 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.1 3.4 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.9 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 2.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 2.2 GO:0031103 axon regeneration(GO:0031103)
0.0 0.6 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 2.1 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 3.0 GO:0060606 neural tube closure(GO:0001843) tube closure(GO:0060606)
0.0 7.8 GO:0007409 axonogenesis(GO:0007409)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 10.8 GO:0036156 inner dynein arm(GO:0036156)
1.9 9.7 GO:0072534 perineuronal net(GO:0072534)
1.3 7.8 GO:0097441 basilar dendrite(GO:0097441)
1.1 8.8 GO:0044305 calyx of Held(GO:0044305)
1.1 3.2 GO:1990032 parallel fiber(GO:1990032)
0.8 7.2 GO:0031209 SCAR complex(GO:0031209)
0.6 2.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.6 7.6 GO:0016342 catenin complex(GO:0016342)
0.5 5.4 GO:0045179 apical cortex(GO:0045179)
0.4 5.9 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.3 5.6 GO:0045277 respiratory chain complex IV(GO:0045277)
0.3 5.8 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.3 2.6 GO:0097512 cardiac myofibril(GO:0097512)
0.2 4.6 GO:0042589 zymogen granule membrane(GO:0042589)
0.2 0.6 GO:0070821 azurophil granule membrane(GO:0035577) tertiary granule membrane(GO:0070821)
0.2 5.6 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 1.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 13.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 11.7 GO:0031225 anchored component of membrane(GO:0031225)
0.1 8.0 GO:0016605 PML body(GO:0016605)
0.1 0.9 GO:0032426 stereocilium tip(GO:0032426)
0.0 15.6 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.0 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 9.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 5.1 GO:0043195 terminal bouton(GO:0043195)
0.0 3.4 GO:0030175 filopodium(GO:0030175)
0.0 1.0 GO:0035371 microtubule plus-end(GO:0035371)
0.0 3.5 GO:0043204 perikaryon(GO:0043204)
0.0 2.7 GO:0005882 intermediate filament(GO:0005882)
0.0 3.0 GO:0043296 apical junction complex(GO:0043296)
0.0 2.2 GO:0043197 dendritic spine(GO:0043197)
0.0 1.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 4.0 GO:0098793 presynapse(GO:0098793)
0.0 5.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 5.1 GO:0016607 nuclear speck(GO:0016607)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 9.3 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690)
1.8 8.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
1.6 12.9 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
1.3 4.0 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
1.1 5.7 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.9 5.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.9 4.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.8 2.4 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.7 9.4 GO:0098879 structural constituent of postsynaptic specialization(GO:0098879) structural constituent of postsynaptic density(GO:0098919)
0.7 2.0 GO:0016403 dimethylargininase activity(GO:0016403)
0.6 7.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.5 3.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.5 4.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.5 3.4 GO:0001849 complement component C1q binding(GO:0001849)
0.4 13.0 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.4 2.2 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.4 2.4 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.4 7.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.3 5.8 GO:0017166 vinculin binding(GO:0017166)
0.3 7.8 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.2 4.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2 0.9 GO:0035514 DNA demethylase activity(GO:0035514) oxidative RNA demethylase activity(GO:0035515)
0.2 5.6 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 4.2 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.1 19.0 GO:0003774 motor activity(GO:0003774)
0.1 15.2 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.1 1.9 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 0.9 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 10.5 GO:0005178 integrin binding(GO:0005178)
0.1 3.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 4.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 5.9 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 1.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 5.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 5.0 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.0 0.5 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 3.0 GO:0051015 actin filament binding(GO:0051015)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0031690 adrenergic receptor binding(GO:0031690)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 12.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.2 4.0 PID FGF PATHWAY FGF signaling pathway
0.2 11.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 3.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 3.6 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 4.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 16.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.7 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 5.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.5 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 9.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.7 8.8 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.6 5.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.4 5.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.3 3.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.3 5.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.3 7.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 7.7 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 5.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 4.0 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.1 2.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 3.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 2.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 5.4 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 2.2 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 3.6 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation