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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Hoxd11_Cdx1_Hoxc11

Z-value: 0.77

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Transcription factors associated with Hoxd11_Cdx1_Hoxc11

Gene Symbol Gene ID Gene Info
ENSRNOG00000051472 homeobox D11
ENSRNOG00000060334 caudal type homeo box 1
ENSRNOG00000016141 homeobox C11

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxd11rn6_v1_chr3_+_61604672_616046720.542.0e-25Click!
Hoxc11rn6_v1_chr7_+_144565392_1445653920.382.8e-12Click!
Cdx1rn6_v1_chr18_-_56355490_56355490-0.044.8e-01Click!

Activity profile of Hoxd11_Cdx1_Hoxc11 motif

Sorted Z-values of Hoxd11_Cdx1_Hoxc11 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_20048121 52.47 ENSRNOT00000014791
meprin 1 subunit alpha
chr4_-_51199570 43.11 ENSRNOT00000010788
solute carrier family 13 member 1
chr16_+_2706428 33.82 ENSRNOT00000077117
interleukin 17 receptor D
chr1_-_207811008 28.42 ENSRNOT00000080506
clarin 3
chr14_-_20920286 23.26 ENSRNOT00000004391
solute carrier family 4 member 4
chr4_+_99063181 22.73 ENSRNOT00000008840
fatty acid binding protein 1
chr4_-_173640684 22.30 ENSRNOT00000010728
RERG like
chr2_-_100249811 20.37 ENSRNOT00000086760
hepatocyte nuclear factor 4, gamma
chr3_+_159902441 20.36 ENSRNOT00000089893
ENSRNOT00000011978
hepatocyte nuclear factor 4, alpha
chr10_-_88060561 20.08 ENSRNOT00000019133
keratin 19
chr20_+_3677474 19.62 ENSRNOT00000047663
metallothionein 1M
chr9_-_60330086 18.53 ENSRNOT00000092162
ENSRNOT00000093630
dynein, axonemal, heavy chain 7
chr8_+_67753279 17.76 ENSRNOT00000009716
calmodulin-like 4
chr1_+_213511874 16.51 ENSRNOT00000078080
ENSRNOT00000016883
cytochrome P450, family 2, subfamily e, polypeptide 1
chr5_-_147784311 16.48 ENSRNOT00000074172
family with sequence similarity 167, member B
chr14_+_12218553 16.36 ENSRNOT00000003237
protein kinase, cGMP-dependent, type II
chr5_+_117698764 15.03 ENSRNOT00000011486
angiopoietin-like 3
chr9_-_52238564 14.51 ENSRNOT00000005073
collagen type V alpha 2 chain
chr3_+_151126591 13.24 ENSRNOT00000025859
myosin heavy chain 7B
chr1_+_41192824 12.92 ENSRNOT00000082133
estrogen receptor 1
chr20_-_14020007 12.55 ENSRNOT00000093521
gamma-glutamyltransferase 1
chr8_-_6235967 12.27 ENSRNOT00000068290
hypothetical protein LOC654482
chr18_-_24823837 10.98 ENSRNOT00000021405
ENSRNOT00000090390
myosin VIIb
chr19_-_22194740 10.91 ENSRNOT00000086187
phosphorylase kinase regulatory subunit beta
chr2_-_154418629 9.99 ENSRNOT00000076274
ENSRNOT00000076165
phospholipase C, eta 1
chr2_+_60920257 9.70 ENSRNOT00000025170
C1q and tumor necrosis factor related protein 3
chr13_+_57243877 9.38 ENSRNOT00000083693
potassium sodium-activated channel subfamily T member 2
chr2_+_8732932 9.21 ENSRNOT00000072849
arrestin domain containing 3
chr17_-_18590536 8.98 ENSRNOT00000078992
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr5_+_167141875 8.90 ENSRNOT00000089314
solute carrier family 2 member 5
chr4_-_82289672 8.87 ENSRNOT00000036394
homeobox A10
chr2_-_204254699 8.75 ENSRNOT00000021487
mab-21 like 3
chr13_-_50514151 8.60 ENSRNOT00000003951
renin
chr20_+_41266566 8.44 ENSRNOT00000000653
fyn-related Src family tyrosine kinase
chr9_+_81689802 8.42 ENSRNOT00000021432
villin 1
chr4_-_178441547 8.19 ENSRNOT00000087434
ENSRNOT00000055542
SRY box 5
chr19_-_37916813 7.92 ENSRNOT00000026585
lecithin cholesterol acyltransferase
chrX_+_112769645 7.88 ENSRNOT00000064478
collagen type IV alpha 5 chain
chr13_-_111972603 7.81 ENSRNOT00000007870
hydroxysteroid 11-beta dehydrogenase 1
chr7_+_116090189 7.79 ENSRNOT00000081571
prostate stem cell antigen
chr5_+_162808646 7.64 ENSRNOT00000021155
dehydrogenase/reductase 3
chr18_-_8360684 7.42 ENSRNOT00000021170
cadherin 2
chr8_+_49621568 7.09 ENSRNOT00000021949
transmembrane protease, serine 13
chr4_+_155313671 6.88 ENSRNOT00000020812
microfibrillar associated protein 5
chr12_-_40590361 6.84 ENSRNOT00000067503
transmembrane protein 116
chr8_+_80965255 6.76 ENSRNOT00000079508
WD repeat domain 72
chr7_+_38742051 6.76 ENSRNOT00000006070
decorin
chr11_+_46108470 6.71 ENSRNOT00000073467
adhesion G protein-coupled receptor G7
chr6_-_42002819 6.50 ENSRNOT00000032417
growth regulation by estrogen in breast cancer 1
chrX_-_139079336 6.34 ENSRNOT00000047605
ubiquitin specific peptidase 26
chr16_+_54291251 6.24 ENSRNOT00000079006
microtubule associated tumor suppressor 1
chr10_+_77537340 6.24 ENSRNOT00000003297
transmembrane protein 100
chrX_+_110789269 6.02 ENSRNOT00000086014
ring finger protein 128, E3 ubiquitin protein ligase
chr7_+_76092503 6.01 ENSRNOT00000079692
grainyhead-like transcription factor 2
chr19_+_9895121 6.00 ENSRNOT00000033953
protease, serine, 54
chr3_+_93648343 5.87 ENSRNOT00000091164

chr4_+_167017816 5.59 ENSRNOT00000055734
taste receptor, type 2, member 145
chr2_+_200572502 5.57 ENSRNOT00000074666
zinc finger protein 697
chrM_+_3904 5.51 ENSRNOT00000040993
mitochondrially encoded NADH dehydrogenase 2
chr1_-_89369960 5.06 ENSRNOT00000028545
hepcidin antimicrobial peptide
chr2_-_88553086 4.91 ENSRNOT00000042494
similar to solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr1_-_238376841 4.84 ENSRNOT00000076393
transmembrane channel-like 1
chr6_+_73358112 4.69 ENSRNOT00000041373
Rho GTPase activating protein 5
chr5_+_167142182 4.69 ENSRNOT00000024054
solute carrier family 2 member 5
chr9_+_52023295 4.68 ENSRNOT00000004956
collagen type III alpha 1 chain
chr8_-_63750531 4.67 ENSRNOT00000009496
neogenin 1
chr3_+_140024043 4.67 ENSRNOT00000086409
Ras and Rab interactor 2
chr4_-_28702559 4.52 ENSRNOT00000013910
ENSRNOT00000013937
calcitonin receptor
chr8_-_109560747 4.51 ENSRNOT00000087334
protein phosphatase 2, regulatory subunit B'', alpha
chr20_+_5008508 4.44 ENSRNOT00000001153
von Willebrand factor A domain containing 7
chr11_+_46793777 4.34 ENSRNOT00000002232
adhesion G protein-coupled receptor G7
chr14_-_66978499 4.29 ENSRNOT00000081601
slit guidance ligand 2
chr7_+_130042947 4.13 ENSRNOT00000089707
pannexin 2
chr1_-_126211439 4.04 ENSRNOT00000014988
tight junction protein 1
chr3_-_78112770 3.96 ENSRNOT00000008396
olfactory receptor 694
chr1_-_169344306 3.82 ENSRNOT00000022852
ubiquilin-like
chr8_+_117906014 3.77 ENSRNOT00000056180
serine peptidase inhibitor, Kazal type 8
chr16_+_22361998 3.74 ENSRNOT00000016193
solute carrier family 18 member A1
chr2_-_154418920 3.72 ENSRNOT00000076326
phospholipase C, eta 1
chr1_+_78546012 3.71 ENSRNOT00000058172
G protein subunit gamma 5
chr18_-_26211445 3.69 ENSRNOT00000027739
neuronal regeneration related protein
chr8_+_119030875 3.64 ENSRNOT00000028458
myosin light chain 3
chr17_-_42127678 3.49 ENSRNOT00000024196
glycosylphosphatidylinositol specific phospholipase D1
chr7_-_134722215 3.48 ENSRNOT00000036750
prickle planar cell polarity protein 1
chr7_-_118332577 3.44 ENSRNOT00000090370
RNA binding protein, fox-1 homolog 2
chr6_-_22138286 3.37 ENSRNOT00000007607
Yip1 domain family, member 4
chr14_+_39368530 3.30 ENSRNOT00000084367
cytochrome c oxidase subunit 7B2
chr15_+_50891127 3.26 ENSRNOT00000020728
stanniocalcin 1
chr10_+_84119884 3.21 ENSRNOT00000009951
homeo box B9
chr4_-_157486844 3.16 ENSRNOT00000038281
ENSRNOT00000022874
COP9 signalosome subunit 7A
chr1_+_193424812 3.11 ENSRNOT00000019939
aquaporin 8
chrX_+_33884499 3.11 ENSRNOT00000090041
RALBP1 associated Eps domain containing protein 2
chr5_+_172488708 3.08 ENSRNOT00000019930
MORN repeat containing 1
chrM_+_8599 3.05 ENSRNOT00000049683
mitochondrially encoded cytochrome C oxidase III
chr8_+_42613601 2.98 ENSRNOT00000040297
olfactory receptor 1264
chr15_+_17775692 2.96 ENSRNOT00000061169
similar to RIKEN cDNA 4933406L09
chr5_+_71742911 2.93 ENSRNOT00000047225
zinc finger protein 462
chr7_-_69982592 2.87 ENSRNOT00000040010
similar to developmental pluripotency associated 5
chr19_+_53044379 2.86 ENSRNOT00000072369
forkhead box C2
chr9_+_73529612 2.85 ENSRNOT00000032430
unc-80 homolog, NALCN activator
chrX_+_104734082 2.77 ENSRNOT00000005020
sushi-repeat-containing protein, X-linked 2
chrM_+_7758 2.75 ENSRNOT00000046201
mitochondrially encoded ATP synthase 8
chr2_-_79078258 2.71 ENSRNOT00000031170
F-box and leucine-rich repeat protein 7
chr7_+_64768742 2.70 ENSRNOT00000005545
glutamate receptor interacting protein 1
chr2_-_250805445 2.69 ENSRNOT00000055362
chloride channel calcium activated 4-like
chr17_-_22143324 2.64 ENSRNOT00000019361
endothelin 1
chrM_+_7919 2.59 ENSRNOT00000046108
mitochondrially encoded ATP synthase 6
chr16_+_50152008 2.53 ENSRNOT00000019237
kallikrein B1
chr6_+_76041669 2.49 ENSRNOT00000039829
family with sequence similarity 177, member A1
chr7_+_34533543 2.43 ENSRNOT00000007412
ENSRNOT00000084185
netrin 4
chr5_-_50221095 2.35 ENSRNOT00000012164
similar to hypothetical protein
chr13_+_91080341 2.35 ENSRNOT00000000058
C-reactive protein
chr2_+_54466280 2.32 ENSRNOT00000033112
complement C6
chr5_-_6186329 2.19 ENSRNOT00000012610
sulfatase 1
chr20_+_5049496 2.17 ENSRNOT00000088251
ENSRNOT00000001118
dimethylarginine dimethylaminohydrolase 2
chr4_-_84131030 2.15 ENSRNOT00000012196
carboxypeptidase, vitellogenic-like
chr6_-_8344574 2.14 ENSRNOT00000009660
prolyl endopeptidase-like
chr10_+_71546977 2.14 ENSRNOT00000041140
acetyl-CoA carboxylase alpha
chr9_+_118586179 2.13 ENSRNOT00000022351
DLG associated protein 1
chr16_-_16762240 2.10 ENSRNOT00000080746

chr4_-_167068838 2.06 ENSRNOT00000029713
taste receptor, type 2, member 125
chr13_-_37697569 2.04 ENSRNOT00000045263
similar to NADH-ubiquinone oxidoreductase B9 subunit (Complex I-B9) (CI-B9)
chr13_+_26463404 2.01 ENSRNOT00000061779
serpin B12-like
chrM_+_2740 1.99 ENSRNOT00000047550
mitochondrially encoded NADH dehydrogenase 1
chr2_-_231409988 1.98 ENSRNOT00000080637
ENSRNOT00000037255
ENSRNOT00000074002
ankyrin 2
chr14_+_104480662 1.97 ENSRNOT00000078710
RAB1A, member RAS oncogene family
chr3_+_54253949 1.97 ENSRNOT00000010018
Beta-1,3-galactosyltransferase 1
chr17_+_32973695 1.90 ENSRNOT00000065674
similar to OTTMUSP00000000621
chr7_+_142575672 1.89 ENSRNOT00000080923
ENSRNOT00000008160
sodium voltage-gated channel alpha subunit 8
chr16_+_74785281 1.85 ENSRNOT00000064316
ENSRNOT00000017106
ENSRNOT00000090646
NIMA-related kinase 3
chr6_+_94835845 1.83 ENSRNOT00000006321
JNK1/MAPK8-associated membrane protein
chr1_+_125124743 1.82 ENSRNOT00000021530
myotubularin related protein 10
chr5_-_113880911 1.77 ENSRNOT00000029441
equatorin
chr4_-_176679815 1.73 ENSRNOT00000090122
glycogen synthase 2
chr1_-_198652674 1.70 ENSRNOT00000023706
TBC1 domain family, member 10b
chr7_+_58814805 1.67 ENSRNOT00000005909
tetraspanin 8
chr1_+_44311513 1.62 ENSRNOT00000065386
T-cell lymphoma invasion and metastasis 2
chr2_+_188745503 1.62 ENSRNOT00000056652
SHC adaptor protein 1
chr3_-_52510507 1.57 ENSRNOT00000091259
sodium voltage-gated channel alpha subunit 1
chr3_-_72219246 1.55 ENSRNOT00000009903
smoothelin-like 1
chr2_-_231409496 1.54 ENSRNOT00000055615
ENSRNOT00000015386
ENSRNOT00000068415
ankyrin 2
chr18_+_35136132 1.53 ENSRNOT00000078731
serine peptidase inhibitor, Kazal type 5
chr17_+_31236015 1.49 ENSRNOT00000023149
solute carrier family 22, member 23
chr14_+_9555264 1.46 ENSRNOT00000002928
NK6 homeobox 1
chr2_+_22910236 1.46 ENSRNOT00000078266
homer scaffolding protein 1
chr12_+_9464026 1.46 ENSRNOT00000048188
caudal type homeo box 2
chr10_+_78416946 1.40 ENSRNOT00000042211

chr9_-_85617954 1.38 ENSRNOT00000077331
serpin family E member 2
chr8_-_23000455 1.34 ENSRNOT00000091027
ENSRNOT00000017493
ral guanine nucleotide dissociation stimulator-like 3
chr4_-_120157477 1.34 ENSRNOT00000046568

chr8_+_118066988 1.32 ENSRNOT00000056161
microtubule-associated protein 4
chr5_-_17399801 1.29 ENSRNOT00000011900
similar to protein tyrosine phosphatase 4a2
chr18_+_29999290 1.28 ENSRNOT00000027372
protocadherin alpha 4
chr11_-_89260297 1.27 ENSRNOT00000057502
scaffolding protein involved in DNA repair
chr1_-_168611670 1.25 ENSRNOT00000021273
olfactory receptor 106
chr1_+_31409579 1.24 ENSRNOT00000016989
similar to RIKEN cDNA 2310057J18
chr2_+_52431601 1.23 ENSRNOT00000023554
3-hydroxy-3-methylglutaryl-CoA synthase 1
chr2_+_193778042 1.20 ENSRNOT00000090212
trichohyalin
chr17_-_14627937 1.19 ENSRNOT00000020532
osteoglycin
chr3_+_43255567 1.17 ENSRNOT00000044419
glycerol-3-phosphate dehydrogenase 2
chr1_+_14797766 1.12 ENSRNOT00000016048
oligodendrocyte transcription factor 3
chr20_+_3364814 1.10 ENSRNOT00000001077
hypothetical protein MGC:15854
chr13_+_95887708 1.09 ENSRNOT00000029081
hypothetical protein LOC689766
chr7_+_64769089 1.04 ENSRNOT00000088861
glutamate receptor interacting protein 1
chr1_+_230811800 0.98 ENSRNOT00000041509
olfactory receptor 384
chr8_+_130350510 0.98 ENSRNOT00000073376
SS18 like 2
chr3_+_48096954 0.98 ENSRNOT00000068238
ENSRNOT00000064344
ENSRNOT00000044638
solute carrier family 4 member 10
chr20_+_29558689 0.95 ENSRNOT00000085229
activating signal cointegrator 1 complex subunit 1
chr8_-_60570058 0.95 ENSRNOT00000009169
S-phase cyclin A-associated protein in the ER
chr13_+_71305548 0.94 ENSRNOT00000074864
similar to putative membrane protein Re9
chr2_+_243577082 0.93 ENSRNOT00000016556
alcohol dehydrogenase 6A (class V)
chr18_+_17403407 0.91 ENSRNOT00000045150
similar to KIAA1328 protein
chr7_-_13404858 0.91 ENSRNOT00000060456
olfactory receptor 1075
chr10_-_63274640 0.90 ENSRNOT00000005129
transmembrane and immunoglobulin domain containing 1
chr20_-_5064469 0.87 ENSRNOT00000001120
lymphocyte antigen 6 complex, locus G6D
chr20_-_1099336 0.87 ENSRNOT00000071766
olfactory receptor-like protein-like
chr3_-_78790691 0.87 ENSRNOT00000008750
olfactory receptor 724
chr6_+_37144787 0.85 ENSRNOT00000075503
RAD51 associated protein 2
chr9_+_16737642 0.80 ENSRNOT00000061430
serum response factor
chr1_+_99616447 0.79 ENSRNOT00000029197
kallikrein related-peptidase 14
chr1_+_80880856 0.78 ENSRNOT00000026060
carcinoembryonic antigen-related cell adhesion molecule 20
chr7_-_145062956 0.73 ENSRNOT00000055274
similar to CDNA sequence BC048502
chr9_-_81879211 0.73 ENSRNOT00000085140
ring finger protein 25
chrX_+_6273733 0.72 ENSRNOT00000074275
NDP, norrin cystine knot growth factor
chr5_+_128881062 0.69 ENSRNOT00000057216
calreticulin 4
chr10_+_84031955 0.69 ENSRNOT00000009934
homeo box B13
chr11_+_28780446 0.68 ENSRNOT00000072546
keratin associated protein 15-1
chr6_-_103949275 0.63 ENSRNOT00000047825

chr1_-_172215730 0.63 ENSRNOT00000055175
olfactory receptor 244
chr13_+_90533365 0.57 ENSRNOT00000082469
DDB1 and CUL4 associated factor 8
chr9_+_66888393 0.52 ENSRNOT00000023536
calcium responsive transcription factor
chr7_+_140829076 0.50 ENSRNOT00000086179
spermatogenesis associated, serine-rich 2
chr8_+_106816152 0.50 ENSRNOT00000047613
Fas apoptotic inhibitory molecule
chr1_+_150492239 0.49 ENSRNOT00000047771
ENSRNOT00000048404

chr18_-_6587080 0.49 ENSRNOT00000040815
60S ribosomal protein L39
chr11_+_43486904 0.48 ENSRNOT00000083800
olfactory receptor 1549
chr2_+_112868707 0.48 ENSRNOT00000017805
neutral cholesterol ester hydrolase 1
chr2_+_166856784 0.46 ENSRNOT00000035765
otolin 1
chr10_+_45322248 0.43 ENSRNOT00000047268
tripartite motif-containing 11
chrX_-_23144324 0.43 ENSRNOT00000000178
ENSRNOT00000081239
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxd11_Cdx1_Hoxc11

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.6 22.7 GO:0051977 lysophospholipid transport(GO:0051977)
5.5 16.4 GO:2001226 negative regulation of chloride transport(GO:2001226)
5.1 20.4 GO:1902569 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
3.6 14.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
3.3 16.5 GO:0016098 monoterpenoid metabolic process(GO:0016098)
3.2 12.9 GO:1990375 baculum development(GO:1990375)
3.1 12.5 GO:0031179 peptide modification(GO:0031179)
3.0 15.0 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
2.7 13.6 GO:0015755 fructose transport(GO:0015755)
2.7 43.1 GO:1902358 sulfate transmembrane transport(GO:1902358)
2.6 7.8 GO:0006713 glucocorticoid catabolic process(GO:0006713)
2.3 9.2 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
2.2 11.0 GO:1904970 brush border assembly(GO:1904970)
2.1 8.4 GO:1902896 regulation of microvillus length(GO:0032532) terminal web assembly(GO:1902896)
1.7 3.5 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
1.7 8.6 GO:0002003 angiotensin maturation(GO:0002003) renin-angiotensin regulation of aldosterone production(GO:0002018)
1.5 4.5 GO:0090247 cell motility involved in somitogenic axis elongation(GO:0090247) regulation of cell motility involved in somitogenic axis elongation(GO:0090249)
1.5 6.0 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
1.5 7.4 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
1.4 4.3 GO:0090024 chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024)
1.4 9.7 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
1.4 8.2 GO:2000741 regulation of timing of neuron differentiation(GO:0060164) positive regulation of mesenchymal stem cell differentiation(GO:2000741)
1.3 24.2 GO:0015701 bicarbonate transport(GO:0015701)
1.3 5.1 GO:1903413 cellular response to bile acid(GO:1903413)
1.2 3.7 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.2 4.7 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
1.1 18.7 GO:0036159 inner dynein arm assembly(GO:0036159)
1.0 4.8 GO:0060005 vestibular reflex(GO:0060005)
1.0 6.8 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.9 6.2 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.9 3.5 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.8 7.9 GO:0034370 triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.8 2.3 GO:0001969 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
0.7 2.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.7 2.9 GO:0072011 apoptotic process involved in outflow tract morphogenesis(GO:0003275) glomerular endothelium development(GO:0072011) glomerular mesangial cell development(GO:0072144) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.7 2.6 GO:0014826 vein smooth muscle contraction(GO:0014826) response to prostaglandin F(GO:0034696) rhythmic excitation(GO:0043179) positive regulation of sarcomere organization(GO:0060298) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.6 20.1 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.6 3.7 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.6 3.5 GO:0051890 regulation of cardioblast differentiation(GO:0051890)
0.6 4.0 GO:0071000 response to magnetism(GO:0071000)
0.5 2.1 GO:0044268 multicellular organismal protein metabolic process(GO:0044268) malonyl-CoA biosynthetic process(GO:2001295)
0.5 3.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.5 2.5 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.5 7.9 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.5 3.4 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.5 4.1 GO:0034214 protein hexamerization(GO:0034214)
0.4 3.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.4 1.3 GO:0051012 microtubule sliding(GO:0051012)
0.4 0.8 GO:0060947 cardiac vascular smooth muscle cell differentiation(GO:0060947)
0.4 2.3 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.3 2.8 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.3 1.4 GO:0061107 seminal vesicle development(GO:0061107)
0.3 8.9 GO:0060065 uterus development(GO:0060065)
0.3 1.5 GO:0002784 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
0.3 2.1 GO:0070842 aggresome assembly(GO:0070842)
0.3 1.5 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.3 3.2 GO:0000338 protein deneddylation(GO:0000338)
0.3 7.1 GO:0061436 establishment of skin barrier(GO:0061436)
0.3 3.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.3 5.1 GO:0070166 enamel mineralization(GO:0070166)
0.2 2.0 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 5.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 1.2 GO:0019563 glycerol catabolic process(GO:0019563)
0.2 0.7 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.2 1.1 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.2 6.0 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.2 1.5 GO:0014807 regulation of somitogenesis(GO:0014807)
0.2 1.9 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.2 6.2 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.2 2.2 GO:0006527 arginine catabolic process(GO:0006527)
0.2 5.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.2 7.6 GO:0042572 retinol metabolic process(GO:0042572)
0.2 4.5 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.2 5.3 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 1.3 GO:0072757 cellular response to camptothecin(GO:0072757)
0.2 3.1 GO:1902572 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.2 3.7 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 6.9 GO:0045761 regulation of adenylate cyclase activity(GO:0045761)
0.1 8.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 4.7 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 2.0 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 1.8 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 4.7 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.1 3.6 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.1 11.3 GO:0044042 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.1 1.5 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 1.6 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 2.7 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 16.5 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.1 0.8 GO:0007320 insemination(GO:0007320)
0.1 0.4 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.4 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 1.9 GO:0019228 neuronal action potential(GO:0019228)
0.1 1.2 GO:0033197 response to vitamin E(GO:0033197)
0.1 1.7 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.4 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.5 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 3.7 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015)
0.0 3.3 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 8.9 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.9 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.4 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 3.2 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.9 GO:0045109 intermediate filament organization(GO:0045109)
0.0 1.5 GO:0048644 muscle organ morphogenesis(GO:0048644)
0.0 7.6 GO:0016042 lipid catabolic process(GO:0016042)
0.0 1.6 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.1 GO:0042245 RNA repair(GO:0042245)
0.0 0.2 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 2.0 GO:0045333 cellular respiration(GO:0045333)
0.0 0.2 GO:1900244 positive regulation of synaptic vesicle endocytosis(GO:1900244)
0.0 0.5 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 1.1 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.5 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 18.5 GO:0036156 inner dynein arm(GO:0036156)
3.6 14.5 GO:0005588 collagen type V trimer(GO:0005588)
2.9 20.1 GO:1990357 terminal web(GO:1990357)
2.8 27.8 GO:0045179 apical cortex(GO:0045179)
1.5 13.2 GO:0097512 cardiac myofibril(GO:0097512)
1.4 10.9 GO:0005964 phosphorylase kinase complex(GO:0005964)
1.3 12.9 GO:0097550 transcriptional preinitiation complex(GO:0097550)
1.2 3.7 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
1.1 19.3 GO:0098644 complex of collagen trimers(GO:0098644)
1.0 3.1 GO:0046691 intracellular canaliculus(GO:0046691)
0.6 6.9 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.6 7.4 GO:0016342 catenin complex(GO:0016342)
0.4 1.8 GO:0002079 inner acrosomal membrane(GO:0002079)
0.4 2.6 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.4 11.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.4 5.3 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.3 4.8 GO:0032426 stereocilium tip(GO:0032426)
0.3 5.8 GO:0032433 filopodium tip(GO:0032433)
0.3 2.3 GO:0005579 membrane attack complex(GO:0005579)
0.3 4.0 GO:0046581 intercellular canaliculus(GO:0046581)
0.3 14.6 GO:0016459 myosin complex(GO:0016459)
0.3 1.5 GO:0097209 epidermal lamellar body(GO:0097209)
0.2 1.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 5.1 GO:0031430 M band(GO:0031430)
0.2 1.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.2 3.3 GO:0045277 respiratory chain complex IV(GO:0045277)
0.2 9.5 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 10.2 GO:0005581 collagen trimer(GO:0005581)
0.2 3.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 10.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.2 1.0 GO:0097441 basilar dendrite(GO:0097441)
0.1 4.1 GO:0005921 gap junction(GO:0005921)
0.1 16.5 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.1 132.9 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 2.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 23.5 GO:0005769 early endosome(GO:0005769)
0.1 3.2 GO:0008180 COP9 signalosome(GO:0008180)
0.1 24.6 GO:0031965 nuclear membrane(GO:0031965)
0.1 7.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 7.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 32.8 GO:0098796 membrane protein complex(GO:0098796)
0.1 19.8 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.8 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.4 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 4.1 GO:0072562 blood microparticle(GO:0072562)
0.0 2.3 GO:0030175 filopodium(GO:0030175)
0.0 2.8 GO:0097060 synaptic membrane(GO:0097060)
0.0 3.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.8 GO:0005770 late endosome(GO:0005770)
0.0 1.7 GO:0072686 mitotic spindle(GO:0072686)
0.0 3.1 GO:0043204 perikaryon(GO:0043204)
0.0 0.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.6 GO:0005795 Golgi stack(GO:0005795)
0.0 3.8 GO:0005768 endosome(GO:0005768)
0.0 2.0 GO:0001650 fibrillar center(GO:0001650)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.1 GO:0005604 basement membrane(GO:0005604)
0.0 3.2 GO:0005911 cell-cell junction(GO:0005911)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 13.7 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
4.2 33.8 GO:0030368 interleukin-17 receptor activity(GO:0030368)
3.9 23.3 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
3.8 22.7 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
3.3 16.4 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690)
2.7 43.1 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
2.6 7.8 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
2.6 12.9 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
2.1 12.5 GO:0003840 gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
1.9 7.6 GO:0035727 lysophosphatidic acid binding(GO:0035727)
1.7 20.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
1.7 15.0 GO:0004859 phospholipase inhibitor activity(GO:0004859)
1.6 7.9 GO:0034186 apolipoprotein A-I binding(GO:0034186)
1.5 13.6 GO:0070061 fructose binding(GO:0070061)
1.4 10.9 GO:0004689 phosphorylase kinase activity(GO:0004689)
1.2 3.7 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
1.1 4.5 GO:0004948 calcitonin receptor activity(GO:0004948)
1.1 4.3 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
1.0 4.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.9 2.6 GO:0031708 endothelin B receptor binding(GO:0031708)
0.8 16.5 GO:0010181 FMN binding(GO:0010181)
0.7 2.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.6 4.0 GO:0071253 connexin binding(GO:0071253)
0.6 7.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.5 2.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.5 4.8 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.5 2.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.5 2.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.5 6.0 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.5 9.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.4 3.5 GO:0004630 phospholipase D activity(GO:0004630)
0.4 4.7 GO:0039706 co-receptor binding(GO:0039706)
0.4 52.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.4 27.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.4 2.4 GO:0043237 laminin-1 binding(GO:0043237)
0.4 1.6 GO:0048408 epidermal growth factor binding(GO:0048408)
0.4 5.6 GO:0033038 bitter taste receptor activity(GO:0033038)
0.4 2.0 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.4 2.3 GO:0001849 complement component C1q binding(GO:0001849)
0.4 1.2 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.4 9.2 GO:0031690 adrenergic receptor binding(GO:0031690)
0.4 16.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.4 1.5 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.4 7.6 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.4 2.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.3 8.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.3 9.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.3 7.5 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3 18.0 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.3 1.3 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3 36.7 GO:0003774 motor activity(GO:0003774)
0.2 1.7 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.2 1.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 2.1 GO:0098919 structural constituent of postsynaptic specialization(GO:0098879) structural constituent of postsynaptic density(GO:0098919)
0.2 3.1 GO:0015250 water channel activity(GO:0015250)
0.2 3.7 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.2 3.5 GO:0031402 sodium ion binding(GO:0031402)
0.1 8.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 4.7 GO:0042169 SH2 domain binding(GO:0042169)
0.1 6.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 3.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.4 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 5.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.8 GO:0070878 primary miRNA binding(GO:0070878)
0.1 2.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.5 GO:0005523 tropomyosin binding(GO:0005523)
0.1 3.5 GO:0030507 spectrin binding(GO:0030507)
0.1 5.9 GO:0015297 antiporter activity(GO:0015297)
0.1 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 5.3 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.1 0.4 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.1 0.9 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 17.7 GO:0003924 GTPase activity(GO:0003924)
0.1 5.7 GO:0030674 protein binding, bridging(GO:0030674)
0.1 5.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0042301 phosphate ion binding(GO:0042301)
0.0 1.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 3.7 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.8 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514) oxidative RNA demethylase activity(GO:0035515)
0.0 1.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 3.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 4.5 GO:0005549 odorant binding(GO:0005549)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 33.0 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.6 27.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.4 21.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.4 26.3 PID FGF PATHWAY FGF signaling pathway
0.3 15.0 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.2 6.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 54.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 6.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 3.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 7.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 4.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 4.0 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 4.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 4.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 6.5 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 0.8 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 3.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 2.6 PID AP1 PATHWAY AP-1 transcription factor network
0.1 9.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.2 PID FOXM1 PATHWAY FOXM1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 16.5 REACTOME XENOBIOTICS Genes involved in Xenobiotics
3.1 43.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
1.6 42.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
1.5 16.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.9 13.6 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.6 10.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.6 27.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.6 6.8 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.4 7.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.4 12.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.3 12.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.3 4.0 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.3 13.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.3 3.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 7.8 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.2 12.9 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.2 2.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 3.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 3.7 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.2 16.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 1.6 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 13.2 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 12.7 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.1 2.1 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.1 2.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 2.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 1.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 2.2 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.2 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 1.4 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 0.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 3.0 REACTOME NEURONAL SYSTEM Genes involved in Neuronal System