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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Hoxb8_Pdx1

Z-value: 1.06

Motif logo

Transcription factors associated with Hoxb8_Pdx1

Gene Symbol Gene ID Gene Info
ENSRNOG00000007585 homeo box B8
ENSRNOG00000046458 pancreatic and duodenal homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxb8rn6_v1_chr10_+_84131495_841314950.331.5e-09Click!
Pdx1rn6_v1_chr12_-_9501213_95012130.115.4e-02Click!

Activity profile of Hoxb8_Pdx1 motif

Sorted Z-values of Hoxb8_Pdx1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_201620642 64.51 ENSRNOT00000093674
deleted in malignant brain tumors 1
chr2_-_105089659 56.60 ENSRNOT00000043381
carboxypeptidase B1
chr7_+_125288081 54.49 ENSRNOT00000085216
parvin, gamma
chr16_-_29936307 44.44 ENSRNOT00000088707
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr3_-_23020441 38.09 ENSRNOT00000017651
nuclear receptor subfamily 5, group A, member 1
chr1_-_197821936 33.68 ENSRNOT00000055027
CD19 molecule
chr10_+_84200880 29.37 ENSRNOT00000011213
homeobox B2
chr16_-_31301880 25.24 ENSRNOT00000084847
ENSRNOT00000083943

chr16_-_71040847 25.16 ENSRNOT00000020606
steroidogenic acute regulatory protein
chr4_-_82133605 23.49 ENSRNOT00000008023
homeobox A2
chr9_-_42839837 22.96 ENSRNOT00000038610
neuralized E3 ubiquitin protein ligase 3
chr7_+_37812831 21.73 ENSRNOT00000005910
BTG anti-proliferation factor 1
chr8_-_114617466 16.96 ENSRNOT00000082992
ENSRNOT00000038160
collagen type VI alpha 5 chain
chr6_-_143195143 16.59 ENSRNOT00000081337

chr2_-_200762492 15.61 ENSRNOT00000056172
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr2_-_200762206 15.56 ENSRNOT00000068511
ENSRNOT00000086835
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr5_-_2803855 15.40 ENSRNOT00000009490
ribosomal protein S8-like
chr9_-_52238564 15.17 ENSRNOT00000005073
collagen type V alpha 2 chain
chr5_-_12172009 14.49 ENSRNOT00000061903
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr9_-_14706557 14.34 ENSRNOT00000048975
triggering receptor expressed on myeloid cells-like 4
chr1_+_15834779 14.24 ENSRNOT00000079069
ENSRNOT00000083012
BCL2-associated transcription factor 1
chr1_+_264893162 13.71 ENSRNOT00000021714
T-cell leukemia, homeobox 1
chr2_-_203680083 13.62 ENSRNOT00000021268
Cd2 molecule
chr9_+_112360419 13.16 ENSRNOT00000086682
mannosidase, alpha, class 2A, member 1
chr3_+_19495628 13.01 ENSRNOT00000077990
immunoglobulin kappa variable 4-57
chr11_+_53140599 12.78 ENSRNOT00000083438
BBX, HMG-box containing
chrX_+_119390013 12.58 ENSRNOT00000074269
angiotensin II receptor, type 2
chr8_-_77398156 12.50 ENSRNOT00000091858
ENSRNOT00000085349
ENSRNOT00000082763
lipase C, hepatic type
chr8_+_44136496 12.47 ENSRNOT00000087022
sodium voltage-gated channel beta subunit 3
chr15_-_36798814 12.21 ENSRNOT00000065764
centromere protein J
chr17_-_39824299 11.70 ENSRNOT00000023412
prolactin
chr3_+_148579920 11.54 ENSRNOT00000012432
HCK proto-oncogene, Src family tyrosine kinase
chr1_-_16687817 11.48 ENSRNOT00000091376
ENSRNOT00000081620
MYB proto-oncogene, transcription factor
chr13_-_83457888 11.42 ENSRNOT00000076289
ENSRNOT00000004065
SFT2 domain containing 2
chrX_-_123486814 11.05 ENSRNOT00000016993
similar to hypothetical protein FLJ22965
chr1_-_198476476 10.94 ENSRNOT00000027525
kinesin family member 22
chr5_-_76261198 10.83 ENSRNOT00000087380

chr13_+_27465930 10.82 ENSRNOT00000003314
serpin family B member 10
chr20_-_5037022 10.80 ENSRNOT00000091022
ENSRNOT00000060762
mutS homolog 5
chr16_-_79700992 10.23 ENSRNOT00000016420
kelch repeat and BTB domain containing 11
chr2_+_235596907 10.10 ENSRNOT00000071463
ENSRNOT00000075728
collagen type XXV alpha 1 chain
chr5_-_50638136 10.08 ENSRNOT00000012519
MOB kinase activator 3B
chr1_-_166912524 10.07 ENSRNOT00000092952
inositol polyphosphate phosphatase-like 1
chr4_+_57952982 10.07 ENSRNOT00000014465
carboxypeptidase A1
chrX_+_35869538 9.98 ENSRNOT00000058947
protein phosphatase with EF-hand domain 1
chr3_-_55451798 9.93 ENSRNOT00000008837
SPC25, NDC80 kinetochore complex component
chr4_-_168517177 9.89 ENSRNOT00000009151
dual specificity phosphatase 16
chr11_+_85508300 9.83 ENSRNOT00000038646

chr2_+_212247451 9.68 ENSRNOT00000027813
vav guanine nucleotide exchange factor 3
chr3_+_17546566 9.66 ENSRNOT00000050825

chr2_-_91497091 9.45 ENSRNOT00000015185
proprotein convertase subtilisin/kexin type 1
chr9_-_119869639 9.40 ENSRNOT00000080498
NDC80 kinetochore complex component
chr6_-_140407307 9.28 ENSRNOT00000079087

chr4_-_163849618 9.24 ENSRNOT00000086363
ENSRNOT00000077637
immunoreceptor Ly49si1
chr11_+_85532526 9.15 ENSRNOT00000036565

chr4_+_70689737 9.10 ENSRNOT00000018852
protease, serine, 2
chr6_+_132510757 8.94 ENSRNOT00000080230
Enah/Vasp-like
chr4_+_102876038 8.81 ENSRNOT00000085205

chr11_+_85618714 8.73 ENSRNOT00000074614

chr2_+_55835151 8.68 ENSRNOT00000018634
FYN binding protein
chr8_-_104155775 8.60 ENSRNOT00000042885
60S ribosomal protein L31-like
chr14_+_43810119 8.55 ENSRNOT00000003327
RNA binding motif protein 47
chr15_-_33285779 8.52 ENSRNOT00000036150
cadherin 24
chr1_-_102826965 8.38 ENSRNOT00000078692
serum amyloid A4
chr9_+_8093262 8.36 ENSRNOT00000080314
adhesion G protein-coupled receptor E4
chr3_+_145764932 8.34 ENSRNOT00000075257

chr7_+_11660934 8.29 ENSRNOT00000022336
lamin B2
chr10_+_61685645 8.26 ENSRNOT00000003933
MAX network transcriptional repressor
chr13_-_61591139 8.09 ENSRNOT00000005324
regulator of G-protein signaling 18
chr4_+_55720010 7.94 ENSRNOT00000063987
fascin actin-bundling protein 3
chr11_+_30904733 7.90 ENSRNOT00000036027
melanocortin 2 receptor accessory protein
chr14_+_45062662 7.90 ENSRNOT00000059124
toll-like receptor 10
chr8_+_132828091 7.83 ENSRNOT00000008269
C-C motif chemokine receptor 9
chr20_-_4817146 7.70 ENSRNOT00000080174
DExD-box helicase 39B
chr3_-_20479999 7.46 ENSRNOT00000050573

chr3_+_72395218 7.42 ENSRNOT00000057616
proteoglycan 3, pro eosinophil major basic protein 2
chr14_-_14390699 7.38 ENSRNOT00000046639
annexin A3
chr1_-_227932603 7.38 ENSRNOT00000033795
membrane spanning 4-domains A6A
chr4_-_62526724 7.29 ENSRNOT00000038950
similar to Solute carrier family 23, member 2 (Sodium-dependent vitamin C transporter 2)
chr4_-_129515435 7.08 ENSRNOT00000039353
EGF domain specific O-linked N-acetylglucosamine transferase
chrX_-_1952111 6.99 ENSRNOT00000061140
jade family PHD finger 3
chr1_-_189182306 6.96 ENSRNOT00000021249
glycoprotein 2
chr10_-_75171774 6.90 ENSRNOT00000011735
eosinophil peroxidase
chr7_-_71139267 6.83 ENSRNOT00000065232
similar to Retinol dehydrogenase type II (RODH II) (29 k-protein)
chr4_+_99823252 6.82 ENSRNOT00000013587
RNA polymerase I subunit A
chr3_-_72171078 6.81 ENSRNOT00000009817
serpin family G member 1
chr1_+_219390523 6.81 ENSRNOT00000054852
G protein-coupled receptor 152
chr6_+_139551751 6.77 ENSRNOT00000081684

chr7_+_133856101 6.76 ENSRNOT00000038686
PDZ domain containing RING finger 4
chr14_+_3506339 6.72 ENSRNOT00000002867
transforming growth factor beta receptor 3
chr4_+_88119838 6.70 ENSRNOT00000073173
vomeronasal 1 receptor 82
chr6_-_139041654 6.55 ENSRNOT00000075664

chrX_+_984798 6.51 ENSRNOT00000073016
zinc finger protein 182
chr6_+_106052212 6.48 ENSRNOT00000010626
signal-induced proliferation-associated 1 like 1
chr1_+_140601791 6.46 ENSRNOT00000091588
interferon stimulated exonuclease gene 20
chr4_-_167202106 6.38 ENSRNOT00000038581
taste receptor, type 2, member 140
chr11_+_85561460 6.36 ENSRNOT00000075455

chr2_-_41871858 6.35 ENSRNOT00000039720
Grb2-binding adaptor protein, transmembrane
chr10_+_47930633 6.28 ENSRNOT00000003515
GRB2-related adaptor protein
chr9_+_67774150 6.27 ENSRNOT00000091060
inducible T-cell co-stimulator
chr1_+_84280945 6.26 ENSRNOT00000057190
SERTA domain containing 3
chr9_+_79944132 6.22 ENSRNOT00000071856
ENSRNOT00000022459
Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
chr6_-_138640187 6.18 ENSRNOT00000087983

chr6_+_139209936 6.10 ENSRNOT00000087620

chr3_+_61658245 6.03 ENSRNOT00000033511
homeo box D3
chr4_-_162856663 6.01 ENSRNOT00000077791
C-type lectin domain family 2, member E
chr10_-_89454681 5.96 ENSRNOT00000028109
BRCA1, DNA repair associated
chr1_-_124803363 5.96 ENSRNOT00000066380
Kruppel-like factor 13
chr1_-_189181901 5.95 ENSRNOT00000092022
glycoprotein 2
chr15_-_34693034 5.93 ENSRNOT00000083314
mast cell protease 8
chr6_-_139747737 5.92 ENSRNOT00000090626

chr20_+_8312792 5.83 ENSRNOT00000083108
cap methyltransferase 1
chr17_-_42276797 5.83 ENSRNOT00000083996
uncharacterized LOC100911664
chr11_+_17538063 5.79 ENSRNOT00000031889
ENSRNOT00000090878
chondrolectin
chr17_+_9596957 5.79 ENSRNOT00000017349
family with sequence similarity 193, member B
chr1_-_271256379 5.74 ENSRNOT00000081605
inositol 1,4,5-trisphosphate receptor-interacting protein-like
chr1_-_267653389 5.69 ENSRNOT00000082550
inositol 1,4,5-trisphosphate receptor-interacting protein-like
chr3_-_118635268 5.68 ENSRNOT00000086357
ATPase phospholipid transporting 8B4 (putative)
chr3_-_47025128 5.66 ENSRNOT00000011682
RNA binding motif, single stranded interacting protein 1
chr5_-_164348713 5.62 ENSRNOT00000087044
similar to casein kinase 1, gamma 3 isoform 2
chr16_-_11214948 5.40 ENSRNOT00000023369
similar to 60S ribosomal protein L38
chr9_-_88748866 5.40 ENSRNOT00000071906
ribosomal protein L30-like 1
chr3_+_118317761 5.40 ENSRNOT00000012700
fibroblast growth factor 7
chr4_-_164536556 5.39 ENSRNOT00000087796
Ly49 inhibitory receptor 2
chr6_-_138536162 5.39 ENSRNOT00000083031

chr12_-_38274036 5.32 ENSRNOT00000063990
kinetochore associated 1
chr16_+_11032531 5.31 ENSRNOT00000078390
WAPL cohesin release factor
chr20_-_5166252 5.28 ENSRNOT00000001138
allograft inflammatory factor 1
chr16_+_61926586 5.28 ENSRNOT00000058884

chr6_+_139345486 5.22 ENSRNOT00000081540

chr6_-_138948583 5.20 ENSRNOT00000084614

chr1_+_7726529 5.12 ENSRNOT00000073460
adenosine deaminase, tRNA-specific 2
chr7_+_63467216 5.10 ENSRNOT00000064349
N-acetylglucosamine-6-sulfatase-like
chr4_-_165456677 4.93 ENSRNOT00000082207
killer cell lectin-like receptor, subfamily A, member 2
chr6_-_141008427 4.89 ENSRNOT00000074472

chr9_+_67699379 4.86 ENSRNOT00000091237
ENSRNOT00000088183
cytotoxic T-lymphocyte-associated protein 4
chr17_-_2660902 4.85 ENSRNOT00000067979
major facilitator superfamily domain containing 14B
chr18_+_79773608 4.84 ENSRNOT00000088484
zinc finger protein 516
chr6_+_29106141 4.84 ENSRNOT00000084560
ATPase family, AAA domain containing 2B
chr1_+_199495298 4.83 ENSRNOT00000086003
ENSRNOT00000026748
integrin subunit alpha D
chr6_-_138679665 4.79 ENSRNOT00000086777

chr20_+_42966140 4.78 ENSRNOT00000000707
myristoylated alanine rich protein kinase C substrate
chrX_+_112311251 4.72 ENSRNOT00000086698

chr13_-_82295123 4.72 ENSRNOT00000090120
similar to hypothetical protein FLJ10706
chr4_+_14039977 4.71 ENSRNOT00000091249
ENSRNOT00000075878
CD36 molecule
chr12_-_52396066 4.70 ENSRNOT00000056712
leucine rich colipase-like 1
chr16_-_23991570 4.70 ENSRNOT00000044198
ENSRNOT00000018854
N-acetyltransferase 2
N-acetyltransferase 1
chr4_-_170740274 4.58 ENSRNOT00000012212
guanylate cyclase 2C
chr1_-_101095594 4.58 ENSRNOT00000027944
Fc fragment of IgG receptor and transporter
chr16_-_7412150 4.55 ENSRNOT00000047252
similar to ribosomal protein S24
chr4_-_132740938 4.52 ENSRNOT00000007185
RING1 and YY1 binding protein
chr17_+_23135985 4.51 ENSRNOT00000090794
neural precursor cell expressed, developmentally down-regulated 9
chr6_+_135610743 4.50 ENSRNOT00000010906
Tnf receptor-associated factor 3
chr6_-_138948424 4.49 ENSRNOT00000072566

chr7_-_1738642 4.38 ENSRNOT00000075554

chr11_-_60931794 4.36 ENSRNOT00000018473
nucleolus and neural progenitor protein
chr16_+_2634603 4.34 ENSRNOT00000019113
HESX homeobox 1
chr1_-_48797631 4.31 ENSRNOT00000082958
1-acylglycerol-3-phosphate O-acyltransferase 4
chr4_-_82177420 4.30 ENSRNOT00000074452
homeobox protein Hox-A6-like
chr17_-_90522091 4.30 ENSRNOT00000077767
lysosomal trafficking regulator
chrX_+_21499934 4.28 ENSRNOT00000090890
ENSRNOT00000081037
HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
chr14_+_19319299 4.27 ENSRNOT00000086542
ankyrin repeat domain 17
chr11_+_88376256 4.26 ENSRNOT00000081776
pre-B lymphocyte 1
chr4_-_162230859 4.25 ENSRNOT00000042872
similar to osteoclast inhibitory lectin
chr8_-_92942076 4.23 ENSRNOT00000056937
family with sequence similarity 46, member A
chr4_-_131694755 4.22 ENSRNOT00000013271
forkhead box P1
chr15_+_60084918 4.22 ENSRNOT00000012632
epithelial stromal interaction 1
chr1_+_22332090 4.20 ENSRNOT00000091252
trace amine-associated receptor 8c (Taar8c), mRNA
chr6_-_138679506 4.16 ENSRNOT00000075376

chr5_+_44270057 4.11 ENSRNOT00000042939
similar to ribosomal protein S12
chr8_-_52828134 4.10 ENSRNOT00000007736
RNA binding motif protein 7
chr15_+_4254499 4.08 ENSRNOT00000061686
annexin A7
chr7_-_14189688 4.06 ENSRNOT00000037456
notch 3
chr5_+_48303366 4.03 ENSRNOT00000009973
gamma-aminobutyric acid type A receptor rho 2 subunit
chrX_+_124894466 4.00 ENSRNOT00000080894
MCTS1, re-initiation and release factor
chr13_-_68253251 3.98 ENSRNOT00000076776
hemicentin 1
chrX_+_77119911 3.96 ENSRNOT00000080141
ATPase copper transporting alpha
chr14_-_72122158 3.91 ENSRNOT00000064495
C1q and tumor necrosis factor related protein 7
chr2_-_196526886 3.88 ENSRNOT00000077325
SET domain, bifurcated 1
chr4_+_166601960 3.87 ENSRNOT00000073394

chr11_-_29638922 3.83 ENSRNOT00000048888
ribosomal protein L29-like
chr13_-_83917001 3.81 ENSRNOT00000004387
ENSRNOT00000082422
RCSD domain containing 1
chr5_+_135412256 3.81 ENSRNOT00000076094
GC-rich promoter binding protein 1-like 1
chr8_+_99632803 3.80 ENSRNOT00000087190
phospholipid scramblase 1
chr14_+_1937041 3.78 ENSRNOT00000000040
transmembrane emp24 protein transport domain containing 11
chr16_-_21338771 3.78 ENSRNOT00000014265
PBX homeobox 4
chr4_-_82263302 3.77 ENSRNOT00000082933
homeobox protein Hox-A6-like
chr10_-_87153982 3.75 ENSRNOT00000014414
keratin 222
chr3_+_4867233 3.73 ENSRNOT00000006754
ribosomal protein L7a
chrX_-_1856258 3.72 ENSRNOT00000079980
similar to RuvB-like protein 1
chr5_+_117586103 3.64 ENSRNOT00000084640
ubiquitin specific peptidase 1
chr15_+_4400991 3.64 ENSRNOT00000008553
ecdysoneless cell cycle regulator
chr13_-_83202864 3.55 ENSRNOT00000003976
X-C motif chemokine ligand 1
chr6_-_139654508 3.49 ENSRNOT00000082576

chr18_+_27632786 3.42 ENSRNOT00000073564
ENSRNOT00000078969
receptor accessory protein 2
chr5_-_150994913 3.41 ENSRNOT00000075506
similar to RIKEN cDNA 2900010J23
chr4_-_82263117 3.40 ENSRNOT00000008542
homeobox protein Hox-A6-like
chr17_-_4123302 3.39 ENSRNOT00000039754
similar to cathepsin M
chr5_+_47546014 3.39 ENSRNOT00000065882
BTB domain and CNC homolog 2
chr7_+_2300434 3.36 ENSRNOT00000071785

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb8_Pdx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
9.8 29.4 GO:0021569 rhombomere 3 development(GO:0021569) rhombomere 4 development(GO:0021570)
9.5 38.1 GO:2000195 negative regulation of female gonad development(GO:2000195)
8.4 25.2 GO:0017143 insecticide metabolic process(GO:0017143)
5.9 35.1 GO:0034757 negative regulation of iron ion transport(GO:0034757)
4.2 12.6 GO:0035566 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) regulation of metanephros size(GO:0035566)
4.2 12.5 GO:0010034 response to acetate(GO:0010034)
3.8 11.5 GO:2000845 positive regulation of testosterone secretion(GO:2000845)
3.8 15.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
3.6 71.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
3.6 3.6 GO:2000537 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
3.2 12.9 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
3.1 12.2 GO:0061511 centriole elongation(GO:0061511)
2.5 35.6 GO:0006968 cellular defense response(GO:0006968)
2.5 7.5 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
2.5 7.4 GO:0045575 basophil activation(GO:0045575)
2.4 14.3 GO:0002457 T cell antigen processing and presentation(GO:0002457)
2.4 9.4 GO:0010157 response to chlorate(GO:0010157)
2.3 6.9 GO:0002215 defense response to nematode(GO:0002215)
2.2 6.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
2.1 4.3 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
2.1 8.5 GO:0016554 cytidine to uridine editing(GO:0016554)
2.0 6.0 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
2.0 21.7 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
1.9 5.8 GO:0036451 cap mRNA methylation(GO:0036451)
1.8 7.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
1.8 5.3 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
1.8 5.3 GO:0014739 positive regulation of muscle hyperplasia(GO:0014739)
1.6 6.4 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
1.6 3.2 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)
1.5 6.0 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
1.5 11.7 GO:0007262 STAT protein import into nucleus(GO:0007262)
1.4 4.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
1.2 4.9 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
1.2 13.2 GO:0006013 mannose metabolic process(GO:0006013)
1.2 9.4 GO:0090267 positive regulation of spindle checkpoint(GO:0090232) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
1.1 13.6 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
1.1 7.7 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
1.0 4.1 GO:0009992 cellular water homeostasis(GO:0009992)
1.0 2.9 GO:0042350 GDP-L-fucose biosynthetic process(GO:0042350)
1.0 6.8 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
1.0 2.9 GO:0080144 amino acid homeostasis(GO:0080144)
0.9 2.8 GO:0032916 positive regulation of transforming growth factor beta3 production(GO:0032916)
0.9 10.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.9 10.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.9 10.0 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.8 2.5 GO:0016488 sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488)
0.8 2.5 GO:0048014 Tie signaling pathway(GO:0048014)
0.8 4.7 GO:0072564 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.8 7.0 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.8 2.3 GO:0000053 argininosuccinate metabolic process(GO:0000053)
0.7 3.7 GO:1904401 cellular response to Thyroid stimulating hormone(GO:1904401)
0.7 8.9 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.7 4.3 GO:0030916 otic vesicle formation(GO:0030916)
0.7 4.8 GO:0031584 activation of phospholipase D activity(GO:0031584) regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.6 3.2 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666) positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.6 2.5 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.6 1.8 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.6 11.5 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.6 58.1 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.6 2.4 GO:0035494 SNARE complex disassembly(GO:0035494)
0.6 2.4 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.6 7.5 GO:0002441 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.6 7.4 GO:0043312 neutrophil degranulation(GO:0043312)
0.6 6.8 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.6 6.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.5 3.8 GO:2000371 phosphatidylserine exposure on apoptotic cell surface(GO:0070782) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.5 6.0 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.5 2.2 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.5 4.8 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.5 3.2 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.5 1.6 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.5 4.1 GO:0072104 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.5 2.0 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.5 4.5 GO:0008063 Toll signaling pathway(GO:0008063)
0.5 1.5 GO:0030576 Cajal body organization(GO:0030576)
0.5 3.5 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.5 12.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.5 4.8 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.5 1.9 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.5 4.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.4 7.8 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.4 2.6 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.4 3.4 GO:0032596 protein transport into membrane raft(GO:0032596)
0.4 10.8 GO:0006298 mismatch repair(GO:0006298)
0.4 12.6 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.4 1.2 GO:0033986 response to methanol(GO:0033986)
0.4 2.8 GO:0010587 miRNA catabolic process(GO:0010587)
0.4 9.1 GO:0030574 collagen catabolic process(GO:0030574)
0.4 1.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4 1.8 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.4 1.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.4 2.5 GO:0048496 maintenance of organ identity(GO:0048496)
0.4 15.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.4 2.5 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.3 10.9 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.3 1.3 GO:0002188 translation reinitiation(GO:0002188)
0.3 4.7 GO:0097068 response to thyroxine(GO:0097068)
0.3 2.7 GO:0006021 inositol biosynthetic process(GO:0006021)
0.3 6.3 GO:0002517 T cell tolerance induction(GO:0002517)
0.3 4.6 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.3 2.3 GO:0098535 de novo centriole assembly(GO:0098535)
0.3 13.7 GO:0048536 spleen development(GO:0048536)
0.3 3.6 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.3 4.5 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.3 11.4 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.3 1.2 GO:0060178 regulation of exocyst localization(GO:0060178)
0.3 5.6 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.3 3.1 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.3 12.7 GO:0050873 brown fat cell differentiation(GO:0050873)
0.3 3.8 GO:0071474 cellular hyperosmotic response(GO:0071474)
0.2 9.8 GO:0006953 acute-phase response(GO:0006953)
0.2 1.8 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 2.3 GO:0097264 self proteolysis(GO:0097264)
0.2 1.0 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.2 2.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.2 1.7 GO:0009235 cobalamin metabolic process(GO:0009235)
0.2 0.8 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.2 1.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 2.0 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.2 3.0 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.2 2.8 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2 1.3 GO:0042447 hormone catabolic process(GO:0042447)
0.2 4.4 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.2 8.7 GO:0045576 mast cell activation(GO:0045576)
0.1 4.3 GO:0016574 histone ubiquitination(GO:0016574)
0.1 2.5 GO:0006677 glycosylceramide metabolic process(GO:0006677)
0.1 7.1 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.1 2.1 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.1 9.3 GO:2001022 positive regulation of response to DNA damage stimulus(GO:2001022)
0.1 2.0 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.1 1.7 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 8.3 GO:0007569 cell aging(GO:0007569)
0.1 4.0 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 2.6 GO:0000154 rRNA modification(GO:0000154)
0.1 1.0 GO:0035745 CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745)
0.1 3.2 GO:0008206 bile acid metabolic process(GO:0008206)
0.1 1.0 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 2.2 GO:0034508 centromere complex assembly(GO:0034508)
0.1 0.9 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1 0.3 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.1 1.6 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 6.2 GO:0007052 mitotic spindle organization(GO:0007052)
0.1 3.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 2.6 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 1.9 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.6 GO:0003416 endochondral bone growth(GO:0003416)
0.1 1.6 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.1 0.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 4.2 GO:1900046 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.1 1.8 GO:0051225 spindle assembly(GO:0051225)
0.1 5.3 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.1 4.3 GO:0002377 immunoglobulin production(GO:0002377)
0.1 2.1 GO:0006378 mRNA polyadenylation(GO:0006378)
0.1 1.3 GO:0045116 protein neddylation(GO:0045116)
0.1 0.4 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.1 0.7 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 3.6 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.1 1.0 GO:0006415 translational termination(GO:0006415)
0.1 0.5 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 1.4 GO:0006284 base-excision repair(GO:0006284)
0.0 0.4 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 6.1 GO:0060348 bone development(GO:0060348)
0.0 4.2 GO:0007586 digestion(GO:0007586)
0.0 1.5 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 2.5 GO:0016575 histone deacetylation(GO:0016575)
0.0 2.5 GO:0050909 sensory perception of taste(GO:0050909)
0.0 1.4 GO:0001658 branching involved in ureteric bud morphogenesis(GO:0001658)
0.0 2.8 GO:0008033 tRNA processing(GO:0008033)
0.0 4.6 GO:0006479 protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.0 0.6 GO:0032438 melanosome organization(GO:0032438) pigment granule organization(GO:0048753)
0.0 4.1 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 2.5 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.5 GO:0007035 vacuolar acidification(GO:0007035)
0.0 3.5 GO:0007286 spermatid development(GO:0007286)
0.0 0.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998) cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0 0.6 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 2.1 GO:0008643 carbohydrate transport(GO:0008643)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.1 GO:0015747 urate transport(GO:0015747)
0.0 0.6 GO:0050688 regulation of defense response to virus(GO:0050688)
0.0 0.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.4 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.4 GO:0060292 long term synaptic depression(GO:0060292)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 19.3 GO:0031262 Ndc80 complex(GO:0031262)
3.8 15.2 GO:0005588 collagen type V trimer(GO:0005588)
3.4 64.5 GO:0042589 zymogen granule membrane(GO:0042589)
2.2 6.7 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
1.8 5.3 GO:1990423 RZZ complex(GO:1990423)
1.5 6.0 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
1.3 21.6 GO:0030061 mitochondrial crista(GO:0030061)
1.2 4.8 GO:0042585 germinal vesicle(GO:0042585) dendritic branch(GO:0044307)
0.9 2.8 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.9 2.6 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.9 7.7 GO:0005688 U6 snRNP(GO:0005688)
0.7 2.9 GO:0044299 C-fiber(GO:0044299)
0.7 2.2 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.7 20.9 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.7 4.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.6 7.7 GO:0035631 CD40 receptor complex(GO:0035631)
0.6 5.0 GO:0005638 lamin filament(GO:0005638)
0.6 9.1 GO:0042581 specific granule(GO:0042581)
0.6 3.6 GO:0097255 R2TP complex(GO:0097255)
0.6 6.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.6 3.3 GO:0097422 tubular endosome(GO:0097422)
0.5 2.1 GO:0042382 paraspeckles(GO:0042382)
0.5 2.1 GO:0048179 activin receptor complex(GO:0048179)
0.5 1.9 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.4 2.6 GO:0070761 pre-snoRNP complex(GO:0070761)
0.4 2.5 GO:1990696 stereocilia ankle link complex(GO:0002142) USH2 complex(GO:1990696)
0.4 6.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.4 5.3 GO:0008278 cohesin complex(GO:0008278)
0.4 3.7 GO:0042788 polysomal ribosome(GO:0042788)
0.4 16.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.4 3.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.3 37.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.3 1.5 GO:0098536 deuterosome(GO:0098536)
0.3 0.8 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.2 9.8 GO:0000795 synaptonemal complex(GO:0000795)
0.2 16.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 12.9 GO:0031225 anchored component of membrane(GO:0031225)
0.2 3.8 GO:0001741 XY body(GO:0001741)
0.2 2.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 5.3 GO:0001891 phagocytic cup(GO:0001891)
0.2 0.4 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.2 1.9 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.2 10.0 GO:0005801 cis-Golgi network(GO:0005801)
0.2 14.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 1.8 GO:0070652 HAUS complex(GO:0070652)
0.2 4.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 2.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 8.0 GO:0015030 Cajal body(GO:0015030)
0.1 14.7 GO:0005902 microvillus(GO:0005902)
0.1 2.9 GO:0005614 interstitial matrix(GO:0005614)
0.1 2.3 GO:0070852 cell body fiber(GO:0070852)
0.1 2.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 2.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 10.9 GO:0072686 mitotic spindle(GO:0072686)
0.1 5.6 GO:0016235 aggresome(GO:0016235)
0.1 8.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 2.4 GO:0030057 desmosome(GO:0030057)
0.1 9.7 GO:0072562 blood microparticle(GO:0072562)
0.1 6.5 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.1 2.9 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 1.8 GO:0033391 chromatoid body(GO:0033391)
0.1 0.5 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 27.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 3.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 4.5 GO:0031519 PcG protein complex(GO:0031519)
0.1 0.3 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 7.9 GO:0005884 actin filament(GO:0005884)
0.1 25.7 GO:0016607 nuclear speck(GO:0016607)
0.1 4.0 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 4.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 3.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 6.7 GO:0005814 centriole(GO:0005814)
0.1 0.6 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.4 GO:0071203 WASH complex(GO:0071203)
0.1 2.2 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 3.1 GO:0000922 spindle pole(GO:0000922)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 2.5 GO:0016605 PML body(GO:0016605)
0.0 0.9 GO:0032420 stereocilium(GO:0032420)
0.0 10.2 GO:0000790 nuclear chromatin(GO:0000790)
0.0 8.7 GO:0005840 ribosome(GO:0005840)
0.0 2.8 GO:0000785 chromatin(GO:0000785)
0.0 6.9 GO:0016604 nuclear body(GO:0016604)
0.0 0.9 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.4 GO:0005883 neurofilament(GO:0005883)
0.0 2.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 33.5 GO:0005654 nucleoplasm(GO:0005654)
0.0 2.6 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 9.5 GO:0005730 nucleolus(GO:0005730)
0.0 3.4 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.9 GO:0045095 keratin filament(GO:0045095)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
10.4 31.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
9.1 63.9 GO:0035375 zymogen binding(GO:0035375)
3.6 14.5 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
2.6 7.9 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
2.5 12.6 GO:0004945 angiotensin type II receptor activity(GO:0004945)
2.4 64.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
2.3 11.5 GO:0071987 WD40-repeat domain binding(GO:0071987)
2.1 12.5 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
1.9 5.8 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
1.8 11.0 GO:0005148 prolactin receptor binding(GO:0005148)
1.6 4.7 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
1.5 7.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
1.4 7.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
1.3 6.5 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
1.1 10.1 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
1.1 25.2 GO:0017127 cholesterol transporter activity(GO:0017127)
1.1 5.4 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
1.0 9.4 GO:0043559 insulin binding(GO:0043559)
1.0 13.2 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
1.0 7.7 GO:0030621 U6 snRNA binding(GO:0017070) U4 snRNA binding(GO:0030621)
0.9 4.7 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.9 2.8 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.9 2.8 GO:1990763 arrestin family protein binding(GO:1990763)
0.9 2.8 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.9 4.6 GO:0019770 IgG receptor activity(GO:0019770)
0.9 2.7 GO:0008254 3'-nucleotidase activity(GO:0008254)
0.8 10.8 GO:0030983 mismatched DNA binding(GO:0030983)
0.8 2.5 GO:0045550 geranylgeranyl reductase activity(GO:0045550)
0.8 2.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.8 4.0 GO:0032767 copper-exporting ATPase activity(GO:0004008) copper-dependent protein binding(GO:0032767) copper-transporting ATPase activity(GO:0043682)
0.8 6.8 GO:0001054 RNA polymerase I activity(GO:0001054)
0.7 9.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.7 2.1 GO:0038100 nodal binding(GO:0038100)
0.7 6.2 GO:0036310 annealing helicase activity(GO:0036310)
0.7 6.7 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.7 8.5 GO:0070097 alpha-catenin binding(GO:0045294) delta-catenin binding(GO:0070097)
0.6 1.9 GO:0004775 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.6 2.5 GO:0001635 calcitonin gene-related peptide receptor activity(GO:0001635)
0.6 1.8 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.6 2.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.6 2.3 GO:0001055 RNA polymerase II activity(GO:0001055)
0.5 6.0 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.5 3.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.5 7.8 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.5 4.2 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.5 2.5 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.5 1.4 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.4 39.1 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.4 3.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.4 3.3 GO:0034452 dynactin binding(GO:0034452)
0.4 2.5 GO:0033142 progesterone receptor binding(GO:0033142)
0.4 6.8 GO:0005522 profilin binding(GO:0005522)
0.4 2.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.4 2.6 GO:1990226 histone methyltransferase binding(GO:1990226)
0.4 1.8 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.4 4.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.4 6.8 GO:0001848 complement binding(GO:0001848)
0.3 10.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.3 2.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.3 3.0 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.3 1.9 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.3 3.8 GO:0042609 CD4 receptor binding(GO:0042609)
0.3 4.6 GO:0015643 toxic substance binding(GO:0015643)
0.3 6.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.3 26.5 GO:0003823 antigen binding(GO:0003823)
0.3 11.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.3 6.3 GO:0031996 thioesterase binding(GO:0031996)
0.3 4.0 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.3 1.0 GO:0030294 receptor signaling protein tyrosine kinase inhibitor activity(GO:0030294)
0.3 5.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 3.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.2 2.6 GO:0051011 microtubule minus-end binding(GO:0051011)
0.2 0.9 GO:0002046 opsin binding(GO:0002046)
0.2 2.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.2 7.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 2.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.2 6.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 4.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 1.8 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.2 30.1 GO:0005057 receptor signaling protein activity(GO:0005057)
0.2 0.7 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.2 4.2 GO:0050681 androgen receptor binding(GO:0050681)
0.2 9.4 GO:0030145 manganese ion binding(GO:0030145)
0.2 13.8 GO:0046332 SMAD binding(GO:0046332)
0.2 2.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.2 2.0 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.1 6.9 GO:0004601 peroxidase activity(GO:0004601)
0.1 2.8 GO:0010181 FMN binding(GO:0010181)
0.1 1.0 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 2.1 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.1 2.8 GO:0070064 proline-rich region binding(GO:0070064)
0.1 2.1 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.1 0.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.3 GO:0030283 testosterone dehydrogenase [NAD(P)] activity(GO:0030283)
0.1 3.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 3.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 2.6 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 1.9 GO:0043422 protein kinase B binding(GO:0043422)
0.1 30.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 4.8 GO:0005080 protein kinase C binding(GO:0005080)
0.1 3.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 6.0 GO:0003684 damaged DNA binding(GO:0003684)
0.1 0.4 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 1.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 0.5 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.1 5.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.0 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 3.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 4.8 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 7.2 GO:0003777 microtubule motor activity(GO:0003777)
0.1 1.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 2.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 19.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 8.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 12.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 1.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 3.0 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 14.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 6.7 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 10.7 GO:0051015 actin filament binding(GO:0051015)
0.1 2.5 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 36.2 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1 6.4 GO:0019905 syntaxin binding(GO:0019905)
0.1 0.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 4.3 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.8 GO:0097602 cullin family protein binding(GO:0097602)
0.0 1.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 18.3 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 3.2 GO:0019955 cytokine binding(GO:0019955)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 8.0 GO:0003682 chromatin binding(GO:0003682)
0.0 0.6 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 1.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.4 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 2.1 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.0 0.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 15.5 GO:0003677 DNA binding(GO:0003677)
0.0 0.5 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 1.1 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 1.7 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0019534 toxin transporter activity(GO:0019534)
0.0 1.2 GO:0002020 protease binding(GO:0002020)
0.0 2.2 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.4 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 57.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.8 34.6 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.8 19.8 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.7 24.7 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.5 25.4 NABA COLLAGENS Genes encoding collagen proteins
0.3 11.7 PID ERBB4 PATHWAY ErbB4 signaling events
0.3 6.0 PID AURORA A PATHWAY Aurora A signaling
0.3 7.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.2 2.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 48.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 7.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 7.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.2 4.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 1.9 ST GAQ PATHWAY G alpha q Pathway
0.2 8.4 PID AURORA B PATHWAY Aurora B signaling
0.2 4.9 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.2 4.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 10.6 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.2 11.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 6.2 PID ATR PATHWAY ATR signaling pathway
0.1 8.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 31.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 3.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 1.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 1.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 2.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 12.5 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 4.5 PID E2F PATHWAY E2F transcription factor network
0.1 3.7 PID NOTCH PATHWAY Notch signaling pathway
0.1 1.8 PID FOXO PATHWAY FoxO family signaling
0.1 2.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 3.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 3.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 2.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.0 PID BMP PATHWAY BMP receptor signaling
0.0 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.2 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 31.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
1.3 11.5 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
1.2 25.2 REACTOME STEROID HORMONES Genes involved in Steroid hormones
1.2 9.4 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.9 8.2 REACTOME DEFENSINS Genes involved in Defensins
0.8 32.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.7 12.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.7 15.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.6 13.2 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.6 11.7 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.5 4.8 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.5 3.2 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.5 4.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.4 9.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.4 4.5 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.4 9.7 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.4 27.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.4 3.6 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.4 10.1 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.4 6.0 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.3 6.8 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.3 5.4 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.3 2.8 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.3 26.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.3 7.2 REACTOME KINESINS Genes involved in Kinesins
0.3 4.9 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.3 3.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.3 6.3 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.3 11.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.2 16.1 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.2 11.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 10.8 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.2 2.6 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2 4.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 2.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 2.8 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.2 5.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.2 1.9 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.2 2.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 8.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 4.0 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 1.9 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 2.4 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 2.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 4.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 6.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 2.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 1.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.8 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 8.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 5.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 1.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 1.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 0.9 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.1 7.9 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.1 6.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 2.1 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 2.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 0.5 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.1 2.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 2.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 4.6 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.1 2.0 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.8 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.1 2.1 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 0.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.1 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 9.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 3.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+