Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation
Downloads

Results for Hoxb7

Z-value: 3.83

Motif logo

Transcription factors associated with Hoxb7

Gene Symbol Gene ID Gene Info
ENSRNOG00000007611 homeo box B7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxb7rn6_v1_chr10_+_84135116_841351160.062.8e-01Click!

Activity profile of Hoxb7 motif

Sorted Z-values of Hoxb7 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_46731403 269.20 ENSRNOT00000017624
teneurin transmembrane protein 3
chr16_-_39476384 234.71 ENSRNOT00000092968
glycoprotein m6a
chrX_-_142164220 206.12 ENSRNOT00000064780
fibroblast growth factor 13
chr1_-_93949187 193.54 ENSRNOT00000018956
zinc finger protein 536
chr11_-_4397361 180.77 ENSRNOT00000046370
cell adhesion molecule 2
chr16_-_39476025 180.55 ENSRNOT00000014312
glycoprotein m6a
chr6_+_48452369 179.34 ENSRNOT00000044310
myelin transcription factor 1-like
chr6_+_64789940 176.90 ENSRNOT00000085979
ENSRNOT00000059739
ENSRNOT00000051908
ENSRNOT00000082793
ENSRNOT00000078583
ENSRNOT00000091677
ENSRNOT00000093241
neuronal cell adhesion molecule
chr3_+_48096954 162.65 ENSRNOT00000068238
ENSRNOT00000064344
ENSRNOT00000044638
solute carrier family 4 member 10
chr3_-_52447622 157.66 ENSRNOT00000083552
sodium voltage-gated channel alpha subunit 1
chr2_+_217963456 155.31 ENSRNOT00000024243
olfactomedin 3
chr9_-_32019205 153.80 ENSRNOT00000016194
adhesion G protein-coupled receptor B3
chr5_+_120340646 153.32 ENSRNOT00000086259
ENSRNOT00000086539
DnaJ heat shock protein family (Hsp40) member C6
chr1_+_240355149 148.88 ENSRNOT00000018521
transient receptor potential cation channel, subfamily M, member 3
chr10_-_8654892 142.27 ENSRNOT00000066534
RNA binding protein, fox-1 homolog 1
chr2_-_89310946 139.45 ENSRNOT00000015195
RALY RNA binding protein-like
chr3_-_48831417 130.38 ENSRNOT00000009920
ENSRNOT00000085246
potassium voltage-gated channel subfamily H member 7
chr3_+_48082935 129.99 ENSRNOT00000087711
ENSRNOT00000067545
solute carrier family 4 member 10
chr4_-_85915099 129.66 ENSRNOT00000016182
neuronal differentiation 6
chr12_-_29743705 128.43 ENSRNOT00000001185
calneuron 1
chr4_-_40385349 124.26 ENSRNOT00000039005
G protein-coupled receptor 85
chr10_-_27862868 124.18 ENSRNOT00000004877
gamma-aminobutyric acid type A receptor alpha 6 subunit
chr8_-_47094352 123.44 ENSRNOT00000048347
glutamate ionotropic receptor kainate type subunit 4
chr17_+_63635086 123.06 ENSRNOT00000020634
disco-interacting protein 2 homolog C
chr9_-_30844199 121.56 ENSRNOT00000017169
collagen type XIX alpha 1 chain
chr10_-_27179900 120.78 ENSRNOT00000082445
gamma-aminobutyric acid type A receptor gamma 2 subunit
chr15_-_77736892 120.66 ENSRNOT00000057924
protocadherin 9
chr3_-_26056818 120.36 ENSRNOT00000044209
LDL receptor related protein 1B
chr3_-_44086006 119.85 ENSRNOT00000034449
ENSRNOT00000082604
ermin
chr14_-_43143973 118.07 ENSRNOT00000003248
ubiquitin C-terminal hydrolase L1
chr7_-_50278842 117.52 ENSRNOT00000088950
synaptotagmin 1
chr3_-_66417741 113.19 ENSRNOT00000007662
neuronal differentiation 1
chr3_+_48106099 111.89 ENSRNOT00000007218
solute carrier family 4 member 10
chr20_-_25826658 106.13 ENSRNOT00000057950
ENSRNOT00000084660
catenin alpha 3
chr2_+_144861455 105.67 ENSRNOT00000093284
ENSRNOT00000019748
ENSRNOT00000072110
doublecortin-like kinase 1
chr4_+_172942020 102.37 ENSRNOT00000072450
LIM domain only 3
chr18_-_37096132 101.58 ENSRNOT00000041188
protein phosphatase 2, regulatory subunit B, beta
chr4_-_55011415 99.58 ENSRNOT00000056996
glutamate metabotropic receptor 8
chr15_+_11298478 98.22 ENSRNOT00000007672
leucine rich repeat containing 3B
chr1_-_279277339 97.91 ENSRNOT00000023667
GDNF family receptor alpha 1
chr2_+_102685513 97.55 ENSRNOT00000033940
basic helix-loop-helix family, member e22
chr15_-_93307420 92.74 ENSRNOT00000012195
SLIT and NTRK-like family, member 1
chr10_+_99388130 92.72 ENSRNOT00000006238
potassium voltage-gated channel subfamily J member 16
chr2_-_173087648 91.51 ENSRNOT00000091079
IQ motif containing J
chr2_-_41784929 91.51 ENSRNOT00000086851
RAB3C, member RAS oncogene family
chr11_-_27971359 90.23 ENSRNOT00000085629
ENSRNOT00000051060
ENSRNOT00000042581
ENSRNOT00000050073
ENSRNOT00000081066
glutamate ionotropic receptor kainate type subunit 1
chr19_+_6046665 89.51 ENSRNOT00000084126
cadherin 8
chr2_-_5577369 89.51 ENSRNOT00000093420
nuclear receptor subfamily 2, group F, member 1
chr3_-_51612397 89.27 ENSRNOT00000081401
sodium voltage-gated channel alpha subunit 3
chr1_+_27476375 87.45 ENSRNOT00000047224
ENSRNOT00000075427
sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2-like
chr2_+_66940057 85.91 ENSRNOT00000043050
cadherin 9
chr10_-_8498422 84.01 ENSRNOT00000082332
RNA binding protein, fox-1 homolog 1
chr4_-_135069970 83.78 ENSRNOT00000008221
contactin 3
chr9_+_73378057 83.55 ENSRNOT00000043627
ENSRNOT00000045766
ENSRNOT00000092445
ENSRNOT00000037974
microtubule-associated protein 2
chr9_+_73334618 83.19 ENSRNOT00000092717
microtubule-associated protein 2
chr15_+_38341089 83.03 ENSRNOT00000015367
fibroblast growth factor 9
chr1_-_173764246 82.69 ENSRNOT00000019690
ENSRNOT00000086944
LIM domain only 1
chr2_-_63166509 82.22 ENSRNOT00000018246
cadherin 6
chrX_+_33884499 81.80 ENSRNOT00000090041
RALBP1 associated Eps domain containing protein 2
chr15_+_104026601 81.27 ENSRNOT00000013520
ENSRNOT00000083269
ENSRNOT00000093403
claudin 10
chr15_-_14737704 80.57 ENSRNOT00000011307
synaptoporin
chr20_+_25990304 80.49 ENSRNOT00000033980
leucine rich repeat transmembrane neuronal 3
chr7_-_83670356 80.45 ENSRNOT00000005584
syntabulin
chr3_+_47677720 80.28 ENSRNOT00000065340
T-box, brain, 1
chr2_-_35104963 78.88 ENSRNOT00000018058
regulator of G-protein signaling 7-binding protein
chr7_-_92996025 78.20 ENSRNOT00000076327
sterile alpha motif domain containing 12
chr2_+_145174876 77.99 ENSRNOT00000040631
mab-21 like 1
chr15_+_96821832 76.94 ENSRNOT00000012785
SLIT and NTRK-like family, member 5
chr17_+_47721977 76.71 ENSRNOT00000080800
amphiphysin-like
chr5_-_109651730 76.57 ENSRNOT00000093032
ELAV like RNA binding protein 2
chr14_+_66598259 76.19 ENSRNOT00000049743
potassium voltage-gated channel interacting protein 4
chr1_+_106998623 75.79 ENSRNOT00000022383
solute carrier family 17 member 6
chr12_-_35979193 74.81 ENSRNOT00000071104
transmembrane protein 132B
chr2_+_69415057 73.78 ENSRNOT00000013152
cadherin 10
chr4_+_94696965 73.78 ENSRNOT00000064696
glutamate ionotropic receptor delta type subunit 2
chrX_-_32153794 73.74 ENSRNOT00000005348
transmembrane protein 27
chr3_+_51687809 73.67 ENSRNOT00000087242
sodium voltage-gated channel alpha subunit 2
chr14_+_114152472 73.08 ENSRNOT00000042965
reticulon 4
chr10_-_27366665 71.82 ENSRNOT00000004725
gamma-aminobutyric acid type A receptor alpha1 subunit
chr1_+_234363994 71.40 ENSRNOT00000018137
RAR-related orphan receptor B
chr9_+_73418607 71.15 ENSRNOT00000092547
microtubule-associated protein 2
chr15_+_17775692 70.76 ENSRNOT00000061169
similar to RIKEN cDNA 4933406L09
chr2_-_231648122 70.70 ENSRNOT00000014962
ankyrin 2
chr10_-_27179254 70.35 ENSRNOT00000004619
gamma-aminobutyric acid type A receptor gamma 2 subunit
chr6_+_83421882 69.14 ENSRNOT00000084258
leucine rich repeat and fibronectin type III domain containing 5
chr14_+_39964588 68.77 ENSRNOT00000003240
gamma-aminobutyric acid type A receptor gamma 1 subunit
chr4_+_110699557 68.62 ENSRNOT00000030588
ENSRNOT00000092261
leucine rich repeat transmembrane neuronal 4
chrX_+_6791136 68.04 ENSRNOT00000003984
norrin-like
chrX_+_23081125 67.88 ENSRNOT00000071639

chrX_-_142248369 67.87 ENSRNOT00000091330
fibroblast growth factor 13
chr15_+_1054937 67.66 ENSRNOT00000008154

chr9_-_85243001 67.63 ENSRNOT00000020219
secretogranin II
chr18_-_6782757 67.31 ENSRNOT00000068150
aquaporin 4
chr2_-_184263564 66.62 ENSRNOT00000015279
F-box and WD repeat domain containing 7
chr6_-_8344574 66.61 ENSRNOT00000009660
prolyl endopeptidase-like
chr2_+_72006099 66.48 ENSRNOT00000034044
cadherin 12
chr9_+_86874685 66.38 ENSRNOT00000041337
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr9_+_118849302 66.36 ENSRNOT00000087592
DLG associated protein 1
chr2_+_11658568 66.20 ENSRNOT00000076408
ENSRNOT00000076416
ENSRNOT00000076992
ENSRNOT00000075931
ENSRNOT00000076136
ENSRNOT00000076481
ENSRNOT00000076084
ENSRNOT00000076230
ENSRNOT00000076710
ENSRNOT00000076239
myocyte enhancer factor 2C
chrX_-_29648359 66.19 ENSRNOT00000086721
ENSRNOT00000006777
glycoprotein m6b
chr5_+_29538380 65.97 ENSRNOT00000010845
calbindin 1
chr15_+_17834635 65.84 ENSRNOT00000085530
similar to RIKEN cDNA 4933406L09
chr4_+_22859622 65.64 ENSRNOT00000073501
ENSRNOT00000068410
ADAM metallopeptidase domain 22
chr5_-_12526962 64.95 ENSRNOT00000092104
suppression of tumorigenicity 18
chr7_-_76294663 64.89 ENSRNOT00000064513
neurocalcin delta
chr7_+_133457255 64.80 ENSRNOT00000080621
contactin 1
chr7_-_66172360 64.73 ENSRNOT00000005537
family with sequence similarity 19 member A2, C-C motif chemokine like
chr5_-_168734296 64.10 ENSRNOT00000066120
calmodulin binding transcription activator 1
chr20_-_54517709 63.98 ENSRNOT00000076234
glutamate ionotropic receptor kainate type subunit 2
chr13_+_106463368 63.62 ENSRNOT00000003489
estrogen-related receptor gamma
chr8_-_120446455 63.60 ENSRNOT00000085161
ENSRNOT00000042854
ENSRNOT00000037199
cAMP regulated phosphoprotein 21
chr7_-_29701586 63.24 ENSRNOT00000009084
ENSRNOT00000089269
anoctamin 4
chr2_-_95472115 62.79 ENSRNOT00000015720
stathmin 2
chr18_-_24182012 62.78 ENSRNOT00000023594
synaptotagmin 4
chr3_-_158328881 62.38 ENSRNOT00000044466
protein tyrosine phosphatase, receptor type, T
chr2_+_116970344 62.34 ENSRNOT00000039603
EGF-like and EMI domain containing 1
chr4_+_24222500 61.65 ENSRNOT00000045346
zinc finger protein 804B
chr4_-_15859132 60.66 ENSRNOT00000082161
calcium voltage-gated channel auxiliary subunit alpha2delta 1
chrX_+_118197217 60.32 ENSRNOT00000090922
5-hydroxytryptamine receptor 2C
chr14_-_28856214 59.85 ENSRNOT00000044659
adhesion G protein-coupled receptor L3
chr1_+_268189277 59.56 ENSRNOT00000065001
sortilin-related VPS10 domain containing receptor 3
chr6_+_8284878 59.46 ENSRNOT00000009581
solute carrier family 3 member 1
chr4_+_136512201 59.39 ENSRNOT00000051645
contactin 6
chr5_-_105579959 59.33 ENSRNOT00000010827
solute carrier family 24 member 2
chr5_+_22392732 59.20 ENSRNOT00000087182
clavesin 1
chr20_+_20378861 59.04 ENSRNOT00000091044
ankyrin 3
chr8_-_84320714 58.93 ENSRNOT00000079356
ENSRNOT00000088487
tubulointerstitial nephritis antigen
chr3_-_25212049 58.07 ENSRNOT00000040023
LDL receptor related protein 1B
chr1_+_198383201 57.44 ENSRNOT00000037405
seizure related 6 homolog like 2
chr4_+_138269142 57.11 ENSRNOT00000007788
contactin 4
chr2_-_57935334 57.09 ENSRNOT00000022319
ENSRNOT00000085599
ENSRNOT00000077790
ENSRNOT00000035821
solute carrier family 1 member 3
chr13_-_49487892 56.51 ENSRNOT00000044972
neurofascin
chr5_+_22380334 56.41 ENSRNOT00000009744
clavesin 1
chrX_+_53053609 56.24 ENSRNOT00000058357
dystrophin
chr2_-_179704629 56.15 ENSRNOT00000083361
ENSRNOT00000077941
glutamate ionotropic receptor AMPA type subunit 2
chr13_-_102857551 56.14 ENSRNOT00000080309
microtubule affinity regulating kinase 1
chr4_+_64088900 55.90 ENSRNOT00000075341
cholinergic receptor, muscarinic 2
chr6_-_23291568 55.88 ENSRNOT00000085708
CAP-GLY domain containing linker protein family, member 4
chr13_-_107886476 55.54 ENSRNOT00000077282
potassium two pore domain channel subfamily K member 2
chr8_-_87419564 55.42 ENSRNOT00000015365
filamin A interacting protein 1
chr9_-_60672246 54.58 ENSRNOT00000017761
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr8_-_14880644 54.45 ENSRNOT00000015977
FAT atypical cadherin 3
chr2_+_18354542 54.28 ENSRNOT00000042958
hyaluronan and proteoglycan link protein 1
chr4_+_70252366 54.25 ENSRNOT00000073039
cell adhesion molecule L1-like
chr12_-_5682608 54.12 ENSRNOT00000076483
FRY microtubule binding protein
chr2_+_74360622 53.54 ENSRNOT00000014013
cadherin 18
chr8_+_82038967 53.45 ENSRNOT00000079535
myosin VA
chrM_+_7919 53.41 ENSRNOT00000046108
mitochondrially encoded ATP synthase 6
chrM_+_10160 53.30 ENSRNOT00000042928
mitochondrially encoded NADH dehydrogenase 4
chrX_-_115175299 53.28 ENSRNOT00000074322
doublecortin
chr9_+_77834091 53.04 ENSRNOT00000033459
von Willebrand factor C domain-containing protein 2-like
chr10_-_66848388 52.97 ENSRNOT00000018891
oligodendrocyte-myelin glycoprotein
chr2_-_111793326 52.53 ENSRNOT00000092660
neuroligin 1
chr18_+_62852303 52.27 ENSRNOT00000087673
G protein subunit alpha L
chr17_+_41798783 52.14 ENSRNOT00000023519
neurensin 1
chr6_-_114476723 52.00 ENSRNOT00000005162
deiodinase, iodothyronine, type II
chr8_-_30222036 51.94 ENSRNOT00000035454
neurotrimin
chr7_+_44009069 51.83 ENSRNOT00000005523
MGAT4 family, member C
chr4_-_21668570 51.68 ENSRNOT00000007723
similar to RIKEN cDNA 9330182L06
chr12_-_10335499 51.52 ENSRNOT00000071567
WAS protein family, member 3
chr1_+_59156251 50.74 ENSRNOT00000017442
limb and CNS expressed 1
chr11_+_20474483 50.72 ENSRNOT00000082417
ENSRNOT00000002895
neural cell adhesion molecule 2
chr15_+_56666012 50.69 ENSRNOT00000013408
5-hydroxytryptamine receptor 2A
chr10_-_21265026 50.63 ENSRNOT00000011922
teneurin transmembrane protein 2
chr1_-_43638161 50.05 ENSRNOT00000024460
interaction protein for cytohesin exchange factors 1
chr1_+_256955652 49.74 ENSRNOT00000020411
leucine-rich, glioma inactivated 1
chr13_-_95250235 49.69 ENSRNOT00000085648
AKT serine/threonine kinase 3
chr14_-_6679878 49.59 ENSRNOT00000075989
ENSRNOT00000067875
secreted phosphoprotein 1
chr17_+_11683862 49.36 ENSRNOT00000024766
msh homeobox 2
chr4_+_21462779 49.16 ENSRNOT00000089747
glutamate metabotropic receptor 3
chr3_-_46726946 49.12 ENSRNOT00000011030
ENSRNOT00000086576
integrin subunit beta 6
chr18_-_14016713 48.90 ENSRNOT00000041125
nucleolar protein 4
chr2_-_184289126 48.73 ENSRNOT00000081678
F-box and WD repeat domain containing 7
chr3_-_57957346 48.72 ENSRNOT00000036728
solute carrier family 25 member 12
chr18_+_65285318 48.64 ENSRNOT00000020431
transcription factor 4
chrX_+_84064427 48.54 ENSRNOT00000046364
zinc finger protein 711
chr5_-_60655985 48.54 ENSRNOT00000093103
F-box protein 10
chr4_+_139670092 48.45 ENSRNOT00000008879
leucine rich repeat neuronal 1
chr5_-_12563429 48.39 ENSRNOT00000059625
suppression of tumorigenicity 18
chrM_+_7758 48.17 ENSRNOT00000046201
mitochondrially encoded ATP synthase 8
chr7_-_58149061 48.17 ENSRNOT00000005157
tryptophan hydroxylase 2
chr9_+_79630604 48.12 ENSRNOT00000021539
ENSRNOT00000083979
transmembrane protein 169
chr13_-_76049363 48.01 ENSRNOT00000075865
ENSRNOT00000007455
BMP/retinoic acid inducible neural specific 2
chr9_-_19613360 47.61 ENSRNOT00000029593
regulator of calcineurin 2
chr3_-_66885085 47.16 ENSRNOT00000084299
ENSRNOT00000090547
phosphodiesterase 1A
chr7_-_44121130 47.13 ENSRNOT00000005706
neurotensin
chr18_-_77579969 47.11 ENSRNOT00000034896
spalt-like transcription factor 3
chr3_-_51643140 46.95 ENSRNOT00000006646
sodium voltage-gated channel alpha subunit 3
chr2_+_263212051 46.55 ENSRNOT00000089396
neuronal growth regulator 1
chr15_+_4209703 46.49 ENSRNOT00000082236
protein phosphatase 3 catalytic subunit beta
chr14_-_66978499 46.11 ENSRNOT00000081601
slit guidance ligand 2
chr13_+_24823488 46.07 ENSRNOT00000019907
cadherin 20
chr2_-_88553086 45.92 ENSRNOT00000042494
similar to solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr6_-_51019407 45.61 ENSRNOT00000011659
G protein-coupled receptor 22
chr18_+_30581530 45.60 ENSRNOT00000048166
protocadherin beta 20
chr2_+_3662763 45.39 ENSRNOT00000017828
multiple C2 and transmembrane domain containing 1
chr4_-_86466797 45.35 ENSRNOT00000017531
phosphodiesterase 1C
chr2_-_88763733 44.80 ENSRNOT00000059424
similar to solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr1_-_16203838 44.70 ENSRNOT00000018556
ENSRNOT00000078586
phosphodiesterase 7B
chr10_-_91661558 44.51 ENSRNOT00000043156

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb7

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
41.2 288.7 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
38.4 115.3 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
38.3 153.3 GO:0072318 clathrin coat disassembly(GO:0072318)
37.0 111.0 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
33.5 167.3 GO:0061743 motor learning(GO:0061743)
30.1 331.0 GO:0097264 self proteolysis(GO:0097264)
29.2 87.6 GO:0021836 chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
28.3 113.1 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
26.5 105.8 GO:0043490 malate-aspartate shuttle(GO:0043490)
26.3 52.5 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
25.9 233.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
24.1 457.8 GO:0021860 pyramidal neuron development(GO:0021860)
22.6 113.2 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
22.0 154.0 GO:0046684 response to pyrethroid(GO:0046684)
21.1 63.4 GO:1904937 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
21.1 63.2 GO:0090247 cell motility involved in somitogenic axis elongation(GO:0090247) regulation of cell motility involved in somitogenic axis elongation(GO:0090249)
20.8 83.4 GO:0051643 endoplasmic reticulum localization(GO:0051643)
20.4 183.6 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
19.6 19.6 GO:0044330 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330)
19.2 153.4 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
18.9 189.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
18.8 262.9 GO:0071420 cellular response to histamine(GO:0071420)
18.7 56.2 GO:0021629 muscle attachment(GO:0016203) olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
18.5 55.5 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
18.5 129.5 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
17.5 105.3 GO:2000987 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
17.5 52.4 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
16.8 67.3 GO:0060354 negative regulation of cell adhesion molecule production(GO:0060354)
16.8 33.6 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
16.5 66.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
16.5 49.6 GO:0006710 androgen catabolic process(GO:0006710)
16.5 165.1 GO:0007412 axon target recognition(GO:0007412)
16.5 66.0 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
16.5 66.0 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
16.5 49.4 GO:0035880 embryonic nail plate morphogenesis(GO:0035880) positive regulation of mesenchymal cell apoptotic process(GO:2001055)
16.1 48.2 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
15.8 157.7 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
15.2 60.7 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
15.2 75.8 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
14.8 74.0 GO:0036233 glycine import(GO:0036233)
14.8 59.0 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
14.4 86.6 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
13.7 41.0 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
13.5 54.1 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
13.5 148.7 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
13.3 106.1 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
12.9 12.9 GO:0031583 phospholipase D-activating G-protein coupled receptor signaling pathway(GO:0031583)
12.8 191.3 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
12.7 241.5 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
12.6 63.2 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
12.6 62.8 GO:2000301 negative regulation of vesicle fusion(GO:0031339) negative regulation of synaptic vesicle exocytosis(GO:2000301)
11.7 70.4 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
11.7 35.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
11.4 34.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
11.3 440.2 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
11.3 90.2 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054) negative regulation of synaptic transmission, GABAergic(GO:0032229)
11.0 44.0 GO:0097105 presynaptic membrane assembly(GO:0097105)
10.8 54.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
10.7 21.4 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
10.5 73.7 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
10.5 31.5 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
10.5 167.5 GO:1901629 regulation of presynaptic membrane organization(GO:1901629)
10.3 123.6 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
10.3 30.8 GO:2000118 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
10.2 51.1 GO:0051964 negative regulation of synapse assembly(GO:0051964)
10.1 60.7 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048) positive regulation of high voltage-gated calcium channel activity(GO:1901843)
10.1 30.2 GO:0032978 protein insertion into membrane from inner side(GO:0032978)
10.0 40.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
10.0 30.0 GO:0015827 angiotensin-mediated drinking behavior(GO:0003051) tryptophan transport(GO:0015827) positive regulation of gap junction assembly(GO:1903598)
9.8 49.1 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
9.7 29.0 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
9.7 19.3 GO:2000468 regulation of peroxidase activity(GO:2000468)
9.6 38.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
9.5 28.5 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
9.4 37.8 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
9.4 47.1 GO:0097332 response to antipsychotic drug(GO:0097332)
9.3 37.0 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
9.0 26.9 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
9.0 62.8 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
8.9 35.8 GO:0031179 peptide modification(GO:0031179)
8.8 79.2 GO:0060484 lung-associated mesenchyme development(GO:0060484)
8.8 43.8 GO:0060023 soft palate development(GO:0060023)
8.7 34.7 GO:0045900 negative regulation of translational elongation(GO:0045900)
8.7 52.0 GO:0042447 hormone catabolic process(GO:0042447)
8.6 60.5 GO:2000020 positive regulation of male gonad development(GO:2000020)
8.5 299.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
8.5 33.9 GO:0051692 cellular oligosaccharide catabolic process(GO:0051692)
8.4 42.0 GO:0019520 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
8.3 25.0 GO:0051866 general adaptation syndrome(GO:0051866)
8.3 66.4 GO:0070842 aggresome assembly(GO:0070842)
8.3 49.7 GO:0021633 optic nerve structural organization(GO:0021633)
8.3 24.8 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
8.2 41.2 GO:0048852 diencephalon morphogenesis(GO:0048852)
8.0 16.0 GO:0098953 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628) protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645)
7.9 31.5 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
7.9 31.5 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
7.8 1098.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
7.8 62.1 GO:0009405 pathogenesis(GO:0009405)
7.7 23.2 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
7.6 38.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
7.6 128.7 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
7.5 246.7 GO:0031114 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
7.4 22.2 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
7.3 101.6 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
7.2 21.7 GO:0016476 regulation of embryonic cell shape(GO:0016476)
7.2 129.7 GO:0021542 dentate gyrus development(GO:0021542)
7.1 149.6 GO:0016048 detection of temperature stimulus(GO:0016048)
7.1 92.5 GO:0046069 cGMP catabolic process(GO:0046069)
7.1 28.2 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
6.9 75.8 GO:0071578 zinc II ion transmembrane import(GO:0071578)
6.8 20.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
6.7 13.5 GO:0010813 neuropeptide catabolic process(GO:0010813)
6.7 26.8 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
6.6 39.8 GO:0060385 axonogenesis involved in innervation(GO:0060385)
6.5 71.4 GO:0035881 amacrine cell differentiation(GO:0035881)
6.5 19.4 GO:0072193 ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
6.2 43.7 GO:0010649 regulation of cell communication by electrical coupling(GO:0010649)
6.2 18.7 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
6.2 31.0 GO:0015889 cobalamin transport(GO:0015889)
6.1 42.9 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
6.0 162.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
6.0 18.0 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
6.0 23.9 GO:0071651 regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877) positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
6.0 17.9 GO:0060988 lipid tube assembly(GO:0060988)
5.9 41.5 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
5.9 342.4 GO:0051965 positive regulation of synapse assembly(GO:0051965)
5.7 131.9 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
5.7 11.5 GO:0072138 mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
5.7 22.6 GO:0007638 mechanosensory behavior(GO:0007638)
5.6 61.8 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
5.6 78.0 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
5.5 32.8 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
5.4 32.4 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
5.2 15.7 GO:1990790 response to glial cell derived neurotrophic factor(GO:1990790) cellular response to glial cell derived neurotrophic factor(GO:1990792)
5.2 26.0 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
5.2 15.5 GO:0035709 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
5.2 10.3 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
5.1 30.8 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
5.1 10.2 GO:1902896 terminal web assembly(GO:1902896)
5.1 20.3 GO:0051660 establishment of centrosome localization(GO:0051660)
5.0 169.1 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
4.9 14.7 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
4.8 43.6 GO:0007097 nuclear migration(GO:0007097)
4.8 154.2 GO:0010107 potassium ion import(GO:0010107)
4.7 18.9 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
4.7 23.5 GO:0097070 ductus arteriosus closure(GO:0097070)
4.6 9.2 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
4.5 72.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
4.5 9.0 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
4.5 63.1 GO:0048245 eosinophil chemotaxis(GO:0048245)
4.4 123.7 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
4.4 122.9 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
4.4 26.3 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
4.4 26.3 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
4.4 30.5 GO:0097084 vascular smooth muscle cell development(GO:0097084)
4.4 21.8 GO:0006564 L-serine biosynthetic process(GO:0006564)
4.3 4.3 GO:0006649 phospholipid transfer to membrane(GO:0006649)
4.3 13.0 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
4.3 17.3 GO:0060178 regulation of exocyst localization(GO:0060178)
4.3 12.8 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
4.3 59.6 GO:1900452 regulation of long term synaptic depression(GO:1900452)
4.2 38.1 GO:0051013 microtubule severing(GO:0051013)
4.2 21.1 GO:0071692 protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
4.2 16.7 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
4.1 8.2 GO:0097325 melanocyte proliferation(GO:0097325)
4.0 8.0 GO:2000078 positive regulation of type B pancreatic cell development(GO:2000078)
4.0 44.1 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
4.0 11.9 GO:0038086 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091) response to formaldehyde(GO:1904404)
3.9 27.6 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
3.9 11.8 GO:0032472 Golgi calcium ion transport(GO:0032472)
3.9 39.3 GO:2001053 regulation of mesenchymal cell apoptotic process(GO:2001053) negative regulation of mesenchymal cell apoptotic process(GO:2001054)
3.9 125.5 GO:0042462 eye photoreceptor cell development(GO:0042462)
3.9 38.8 GO:0006677 glycosylceramide metabolic process(GO:0006677)
3.9 30.8 GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
3.8 57.4 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
3.7 11.2 GO:0086028 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
3.7 18.7 GO:0035063 nuclear speck organization(GO:0035063)
3.7 82.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
3.6 50.7 GO:0007413 axonal fasciculation(GO:0007413)
3.6 35.6 GO:0021891 olfactory bulb interneuron development(GO:0021891)
3.5 10.4 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
3.4 24.0 GO:0000103 sulfate assimilation(GO:0000103)
3.4 16.8 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
3.3 30.0 GO:0045760 positive regulation of action potential(GO:0045760)
3.3 36.4 GO:0009642 response to light intensity(GO:0009642)
3.2 70.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
3.1 65.6 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
3.1 59.3 GO:0060292 long term synaptic depression(GO:0060292)
3.1 9.3 GO:0061303 cornea development in camera-type eye(GO:0061303)
3.1 24.6 GO:0051694 pointed-end actin filament capping(GO:0051694)
2.9 11.6 GO:0071313 cellular response to caffeine(GO:0071313)
2.9 14.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
2.9 109.6 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
2.9 8.6 GO:1904746 glomerular endothelium development(GO:0072011) negative regulation of apoptotic process involved in morphogenesis(GO:1902338) negative regulation of apoptotic process involved in development(GO:1904746)
2.9 28.5 GO:0019695 choline metabolic process(GO:0019695)
2.8 41.5 GO:0048149 behavioral response to ethanol(GO:0048149)
2.7 13.4 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
2.7 13.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
2.7 29.2 GO:0007602 phototransduction(GO:0007602)
2.5 10.1 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
2.5 14.9 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
2.5 131.0 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
2.5 34.6 GO:0007256 activation of JNKK activity(GO:0007256)
2.5 22.2 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
2.4 24.3 GO:0001778 plasma membrane repair(GO:0001778)
2.4 4.8 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
2.4 28.7 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
2.3 7.0 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
2.3 9.2 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
2.2 28.8 GO:0019985 translesion synthesis(GO:0019985)
2.1 87.5 GO:0002028 regulation of sodium ion transport(GO:0002028)
2.1 18.9 GO:0048739 cardiac muscle fiber development(GO:0048739)
2.1 53.5 GO:0048679 regulation of axon regeneration(GO:0048679)
2.0 4.0 GO:1902276 amylase secretion(GO:0036394) pancreatic amylase secretion(GO:0036395) regulation of pancreatic amylase secretion(GO:1902276)
2.0 50.7 GO:0097352 autophagosome maturation(GO:0097352)
1.9 13.5 GO:0051036 regulation of endosome size(GO:0051036)
1.9 26.8 GO:0031643 positive regulation of myelination(GO:0031643)
1.9 7.5 GO:0050957 equilibrioception(GO:0050957)
1.9 9.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
1.8 14.7 GO:0061042 vascular wound healing(GO:0061042)
1.7 12.2 GO:0032808 lacrimal gland development(GO:0032808)
1.7 19.1 GO:0010669 epithelial structure maintenance(GO:0010669)
1.7 92.5 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
1.7 28.8 GO:1902358 sulfate transmembrane transport(GO:1902358)
1.7 16.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
1.6 19.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
1.6 9.6 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
1.6 7.9 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
1.6 3.1 GO:1901963 regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963)
1.6 9.4 GO:2000169 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
1.5 13.8 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
1.5 10.6 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
1.5 3.0 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
1.5 14.7 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
1.5 8.8 GO:0048752 semicircular canal morphogenesis(GO:0048752)
1.5 11.6 GO:0048840 otolith development(GO:0048840)
1.5 4.4 GO:0061470 T follicular helper cell differentiation(GO:0061470)
1.4 10.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
1.4 38.5 GO:2000272 negative regulation of receptor activity(GO:2000272)
1.4 9.9 GO:0071000 response to magnetism(GO:0071000)
1.4 11.2 GO:0097369 sodium ion import(GO:0097369)
1.3 6.7 GO:0008295 spermidine biosynthetic process(GO:0008295)
1.3 10.6 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
1.3 17.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
1.3 18.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
1.3 5.1 GO:0051971 positive regulation of transmission of nerve impulse(GO:0051971)
1.3 48.3 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
1.3 16.5 GO:0006622 protein targeting to lysosome(GO:0006622)
1.3 8.8 GO:0071233 cellular response to leucine(GO:0071233)
1.2 4.9 GO:0071492 cellular response to UV-A(GO:0071492)
1.2 117.5 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
1.2 12.8 GO:0030828 positive regulation of cGMP metabolic process(GO:0030825) positive regulation of cGMP biosynthetic process(GO:0030828)
1.2 48.6 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071)
1.1 14.9 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
1.1 2.3 GO:0060789 hair follicle placode formation(GO:0060789)
1.1 10.0 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
1.0 22.9 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
1.0 3.1 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
1.0 4.1 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
1.0 22.6 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
1.0 13.3 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
1.0 26.6 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
1.0 9.1 GO:0072501 cellular divalent inorganic anion homeostasis(GO:0072501)
1.0 8.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
1.0 11.0 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
1.0 4.9 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
1.0 6.8 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.9 29.8 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.9 35.3 GO:0042220 response to cocaine(GO:0042220)
0.9 6.3 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.9 12.2 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.9 19.2 GO:0045109 intermediate filament organization(GO:0045109)
0.9 24.3 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.9 6.9 GO:1900040 regulation of interleukin-2 secretion(GO:1900040) positive regulation of interleukin-2 secretion(GO:1900042)
0.9 21.4 GO:0044705 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.8 99.0 GO:0008360 regulation of cell shape(GO:0008360)
0.8 19.5 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.8 3.2 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.8 35.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.8 50.3 GO:0021549 cerebellum development(GO:0021549)
0.8 3.2 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.8 3.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.8 40.1 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.8 20.0 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.7 18.0 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.7 4.4 GO:0032288 myelin assembly(GO:0032288)
0.7 9.5 GO:0043586 tongue development(GO:0043586)
0.7 10.0 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.7 23.3 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.7 4.8 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.7 59.5 GO:0006865 amino acid transport(GO:0006865)
0.7 2.0 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.6 83.6 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.6 9.0 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.6 9.3 GO:0098926 postsynaptic signal transduction(GO:0098926)
0.6 4.0 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.5 10.9 GO:0060143 positive regulation of syncytium formation by plasma membrane fusion(GO:0060143)
0.5 12.3 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.5 1.5 GO:0048664 neuron fate determination(GO:0048664)
0.5 7.5 GO:0030517 negative regulation of axon extension(GO:0030517)
0.5 46.9 GO:0032526 response to retinoic acid(GO:0032526)
0.5 31.2 GO:0045333 cellular respiration(GO:0045333)
0.4 1.7 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.4 1.7 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.4 1.3 GO:0060005 vestibular reflex(GO:0060005)
0.4 29.6 GO:0090630 activation of GTPase activity(GO:0090630)
0.4 3.2 GO:0001967 suckling behavior(GO:0001967)
0.4 0.8 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.4 4.4 GO:0042534 tumor necrosis factor biosynthetic process(GO:0042533) regulation of tumor necrosis factor biosynthetic process(GO:0042534)
0.4 1.1 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.4 3.9 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.3 2.4 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.3 25.8 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.3 3.0 GO:0070327 thyroid hormone transport(GO:0070327)
0.3 13.7 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.3 4.3 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.3 23.6 GO:0050806 positive regulation of synaptic transmission(GO:0050806)
0.3 8.6 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.3 25.6 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.3 3.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.3 0.8 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.3 4.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.2 8.1 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.2 10.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.2 17.2 GO:0030010 establishment of cell polarity(GO:0030010)
0.2 2.8 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.2 20.9 GO:0019882 antigen processing and presentation(GO:0019882)
0.2 17.6 GO:0019722 calcium-mediated signaling(GO:0019722)
0.2 8.5 GO:0048278 vesicle docking(GO:0048278)
0.2 4.4 GO:0006298 mismatch repair(GO:0006298)
0.2 2.8 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.2 4.7 GO:0060976 coronary vasculature development(GO:0060976)
0.2 6.0 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.2 0.5 GO:0033386 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386) farnesyl diphosphate biosynthetic process(GO:0045337)
0.2 0.6 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.4 GO:0017143 insecticide metabolic process(GO:0017143)
0.1 0.7 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.1 0.6 GO:0070417 cellular response to cold(GO:0070417)
0.1 5.9 GO:1902749 regulation of cell cycle G2/M phase transition(GO:1902749)
0.1 2.7 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.1 2.9 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.1 1.3 GO:0048538 thymus development(GO:0048538)
0.1 1.9 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 0.2 GO:2001279 regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
0.0 2.1 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.0 8.1 GO:0001822 kidney development(GO:0001822)
0.0 1.3 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.7 GO:0007099 centriole replication(GO:0007099)
0.0 0.5 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.6 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.6 GO:0009855 specification of symmetry(GO:0009799) determination of bilateral symmetry(GO:0009855)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
71.4 642.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
46.3 277.7 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
27.8 83.4 GO:0042642 actomyosin, myosin complex part(GO:0042642)
23.1 115.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
20.0 119.9 GO:0033269 internode region of axon(GO:0033269)
19.4 523.8 GO:0043194 axon initial segment(GO:0043194)
19.3 116.0 GO:0042584 chromaffin granule membrane(GO:0042584)
16.2 243.3 GO:0043083 synaptic cleft(GO:0043083)
15.0 344.9 GO:1902711 GABA-A receptor complex(GO:1902711)
14.6 43.8 GO:0005592 collagen type XI trimer(GO:0005592)
12.7 38.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
12.7 76.4 GO:0016012 sarcoglycan complex(GO:0016012)
12.3 37.0 GO:0098855 HCN channel complex(GO:0098855)
12.1 386.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
11.4 466.6 GO:0044295 axonal growth cone(GO:0044295)
9.6 143.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
9.6 9.6 GO:0014801 longitudinal sarcoplasmic reticulum(GO:0014801)
9.3 55.9 GO:0032280 symmetric synapse(GO:0032280)
9.3 130.4 GO:0031045 dense core granule(GO:0031045)
9.1 618.4 GO:0014704 intercalated disc(GO:0014704)
8.9 80.4 GO:0097433 dense body(GO:0097433)
8.8 70.4 GO:0031209 SCAR complex(GO:0031209)
8.2 123.7 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
7.8 156.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
7.7 46.5 GO:0005955 calcineurin complex(GO:0005955)
7.1 78.0 GO:0070852 cell body fiber(GO:0070852)
7.0 118.6 GO:0044291 cell-cell contact zone(GO:0044291)
6.9 55.5 GO:0044305 calyx of Held(GO:0044305)
6.8 41.0 GO:0032584 growth cone membrane(GO:0032584)
6.6 257.1 GO:0032809 neuronal cell body membrane(GO:0032809)
6.2 73.8 GO:0030008 TRAPP complex(GO:0030008)
6.1 164.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
5.6 581.5 GO:0031225 anchored component of membrane(GO:0031225)
5.6 16.8 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
5.5 77.5 GO:0032433 filopodium tip(GO:0032433)
5.1 10.2 GO:1990357 terminal web(GO:1990357)
4.8 19.3 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
4.7 14.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
4.7 42.0 GO:0071821 FANCM-MHF complex(GO:0071821)
4.4 114.9 GO:0030673 axolemma(GO:0030673)
4.4 52.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
4.3 221.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
4.3 21.7 GO:0005940 septin ring(GO:0005940)
4.3 12.9 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
4.3 115.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
4.3 42.8 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
4.2 12.5 GO:0044308 axonal spine(GO:0044308)
3.7 55.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
3.7 14.7 GO:0070545 PeBoW complex(GO:0070545)
3.6 40.0 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
3.5 35.3 GO:0042788 polysomal ribosome(GO:0042788)
3.5 41.4 GO:0045275 respiratory chain complex III(GO:0045275)
3.4 27.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
3.4 73.8 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
3.1 21.4 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
2.9 47.0 GO:0030061 mitochondrial crista(GO:0030061)
2.9 20.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
2.9 498.8 GO:0045211 postsynaptic membrane(GO:0045211)
2.8 117.0 GO:1904115 axon cytoplasm(GO:1904115)
2.7 73.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
2.7 24.3 GO:0005826 actomyosin contractile ring(GO:0005826)
2.7 18.9 GO:0005827 polar microtubule(GO:0005827)
2.7 34.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
2.6 13.0 GO:0070695 FHF complex(GO:0070695)
2.6 167.8 GO:0031901 early endosome membrane(GO:0031901)
2.4 28.8 GO:0005796 Golgi lumen(GO:0005796)
2.3 38.7 GO:0000930 gamma-tubulin complex(GO:0000930)
2.2 44.4 GO:0010369 chromocenter(GO:0010369)
2.2 31.0 GO:0043202 lysosomal lumen(GO:0043202)
2.2 154.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
2.1 17.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
2.0 8.2 GO:0071438 invadopodium membrane(GO:0071438)
2.0 22.4 GO:0043196 varicosity(GO:0043196)
2.0 340.7 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
2.0 13.8 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
1.9 22.6 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
1.8 272.8 GO:0005802 trans-Golgi network(GO:0005802)
1.7 27.6 GO:0097225 sperm midpiece(GO:0097225)
1.7 20.3 GO:0097539 ciliary transition fiber(GO:0097539)
1.7 30.3 GO:0030131 clathrin adaptor complex(GO:0030131)
1.7 11.6 GO:0030314 junctional membrane complex(GO:0030314)
1.6 67.3 GO:0009925 basal plasma membrane(GO:0009925)
1.6 49.1 GO:0008305 integrin complex(GO:0008305)
1.6 4.8 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
1.6 167.5 GO:0098794 postsynapse(GO:0098794)
1.5 16.2 GO:0002177 manchette(GO:0002177)
1.5 4.4 GO:0030906 retromer, cargo-selective complex(GO:0030906)
1.5 11.6 GO:0043020 NADPH oxidase complex(GO:0043020)
1.4 33.9 GO:0035371 microtubule plus-end(GO:0035371)
1.3 10.0 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
1.2 34.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
1.2 137.7 GO:0030427 site of polarized growth(GO:0030427)
1.2 988.4 GO:0005887 integral component of plasma membrane(GO:0005887)
1.2 20.4 GO:0070469 respiratory chain(GO:0070469)
1.2 13.0 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
1.2 10.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
1.1 11.0 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
1.1 100.4 GO:0008021 synaptic vesicle(GO:0008021)
1.1 68.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
1.1 24.6 GO:0005865 striated muscle thin filament(GO:0005865)
1.0 3.1 GO:1990909 Wnt signalosome(GO:1990909)
1.0 6.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
1.0 4.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
1.0 13.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.9 76.4 GO:0030018 Z disc(GO:0030018)
0.9 48.4 GO:0043679 axon terminus(GO:0043679)
0.9 214.5 GO:0030425 dendrite(GO:0030425)
0.8 7.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.8 24.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.8 37.0 GO:0045171 intercellular bridge(GO:0045171)
0.8 18.6 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.8 10.0 GO:0000242 pericentriolar material(GO:0000242)
0.8 16.6 GO:0097546 ciliary base(GO:0097546)
0.7 22.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.7 14.2 GO:0070822 Sin3-type complex(GO:0070822)
0.7 4.5 GO:0031430 M band(GO:0031430)
0.7 45.2 GO:0045177 apical part of cell(GO:0045177)
0.7 113.4 GO:0043025 neuronal cell body(GO:0043025)
0.7 2.0 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.7 8.5 GO:0060170 ciliary membrane(GO:0060170)
0.6 9.1 GO:0071565 nBAF complex(GO:0071565)
0.6 51.0 GO:0005814 centriole(GO:0005814)
0.6 4.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.6 13.2 GO:0005839 proteasome core complex(GO:0005839)
0.6 18.8 GO:0016235 aggresome(GO:0016235)
0.5 31.1 GO:0030424 axon(GO:0030424)
0.5 12.5 GO:0001533 cornified envelope(GO:0001533)
0.5 8.5 GO:0031201 SNARE complex(GO:0031201)
0.5 3.0 GO:0035189 Rb-E2F complex(GO:0035189)
0.5 12.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.5 57.2 GO:0045202 synapse(GO:0045202)
0.5 7.7 GO:0030126 COPI vesicle coat(GO:0030126)
0.4 14.7 GO:0008180 COP9 signalosome(GO:0008180)
0.4 5.9 GO:0032421 stereocilium bundle(GO:0032421)
0.4 14.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.3 16.3 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.3 7.9 GO:0005844 polysome(GO:0005844)
0.2 35.7 GO:0005874 microtubule(GO:0005874)
0.2 17.2 GO:0005795 Golgi stack(GO:0005795)
0.2 1.3 GO:0032426 stereocilium tip(GO:0032426)
0.2 1.9 GO:0030118 clathrin coat(GO:0030118)
0.2 21.2 GO:0043235 receptor complex(GO:0043235)
0.2 9.3 GO:0016592 mediator complex(GO:0016592)
0.2 7.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 13.7 GO:0005923 bicellular tight junction(GO:0005923)
0.2 8.7 GO:0030027 lamellipodium(GO:0030027)
0.2 8.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.2 37.9 GO:0015629 actin cytoskeleton(GO:0015629)
0.1 5.4 GO:0072686 mitotic spindle(GO:0072686)
0.1 8.3 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 2.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 7.1 GO:0031252 cell leading edge(GO:0031252)
0.1 4.7 GO:1990391 DNA repair complex(GO:1990391)
0.1 1.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 270.4 GO:0016021 integral component of membrane(GO:0016021)
0.0 0.2 GO:0034451 centriolar satellite(GO:0034451)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
57.8 462.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
47.7 333.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
39.2 196.0 GO:0008503 benzodiazepine receptor activity(GO:0008503)
37.7 339.5 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
37.0 111.0 GO:0071886 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding(GO:0071886)
36.1 180.3 GO:0030348 syntaxin-3 binding(GO:0030348)
29.5 118.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
29.4 88.2 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
25.9 103.7 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
24.9 99.6 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
23.6 70.9 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
23.1 92.5 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
23.1 115.3 GO:0050816 phosphothreonine binding(GO:0050816)
22.5 67.5 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
20.2 60.7 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
17.6 52.9 GO:1990763 arrestin family protein binding(GO:1990763)
17.5 52.4 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
17.0 170.0 GO:0003680 AT DNA binding(GO:0003680)
16.5 66.0 GO:0099510 calcium ion binding involved in regulation of cytosolic calcium ion concentration(GO:0099510)
16.4 49.2 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
15.9 63.6 GO:0050682 AF-2 domain binding(GO:0050682)
14.6 410.0 GO:0031402 sodium ion binding(GO:0031402)
14.4 404.5 GO:0005452 inorganic anion exchanger activity(GO:0005452)
14.3 71.4 GO:0008502 melatonin receptor activity(GO:0008502)
13.9 55.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
13.4 160.6 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
13.1 301.3 GO:0002162 dystroglycan binding(GO:0002162)
12.7 38.0 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
12.3 147.5 GO:0008046 axon guidance receptor activity(GO:0008046)
11.8 270.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
11.6 46.5 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
11.4 57.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
11.3 33.9 GO:0017042 glycosylceramidase activity(GO:0017042)
10.9 109.2 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
10.1 30.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
9.5 38.1 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
9.4 65.9 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
8.9 35.8 GO:0016842 amidine-lyase activity(GO:0016842)
8.9 26.7 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
8.7 234.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
8.6 103.5 GO:0070008 serine-type exopeptidase activity(GO:0070008)
8.3 33.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
8.2 41.0 GO:0005042 netrin receptor activity(GO:0005042)
7.9 31.5 GO:0008940 nitrate reductase activity(GO:0008940)
7.8 38.8 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
7.7 30.8 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
7.6 105.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
7.4 22.2 GO:0019807 aspartoacylase activity(GO:0019807)
7.3 29.0 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
7.0 42.0 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
6.9 54.9 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
6.7 47.1 GO:0001595 angiotensin receptor activity(GO:0001595)
6.7 313.5 GO:0017080 sodium channel regulator activity(GO:0017080)
6.6 39.7 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
6.5 19.6 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
6.4 19.3 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
6.3 18.9 GO:0031208 POZ domain binding(GO:0031208)
6.2 30.8 GO:1902282 A-type (transient outward) potassium channel activity(GO:0005250) voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
6.1 72.9 GO:0030215 semaphorin receptor binding(GO:0030215)
5.7 40.1 GO:0015368 calcium:cation antiporter activity(GO:0015368)
5.6 163.8 GO:0017075 syntaxin-1 binding(GO:0017075)
5.6 22.4 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
5.5 210.7 GO:0005227 calcium activated cation channel activity(GO:0005227)
5.5 49.7 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
5.5 125.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
5.2 62.4 GO:0045294 alpha-catenin binding(GO:0045294)
5.2 41.4 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
5.2 15.5 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
5.1 20.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
5.1 66.4 GO:0098919 structural constituent of postsynaptic specialization(GO:0098879) structural constituent of postsynaptic density(GO:0098919)
4.9 73.8 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
4.9 233.5 GO:0015459 potassium channel regulator activity(GO:0015459)
4.8 115.7 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
4.8 14.4 GO:0042296 ISG15 transferase activity(GO:0042296)
4.8 67.3 GO:0015250 water channel activity(GO:0015250)
4.8 28.5 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
4.7 28.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
4.7 56.1 GO:0070300 phosphatidic acid binding(GO:0070300)
4.6 68.8 GO:0050811 GABA receptor binding(GO:0050811)
4.5 103.8 GO:0031489 myosin V binding(GO:0031489)
4.4 31.0 GO:0030492 hemoglobin binding(GO:0030492)
4.4 30.5 GO:0071253 connexin binding(GO:0071253)
4.3 12.9 GO:0031708 endothelin B receptor binding(GO:0031708)
4.3 439.5 GO:0005262 calcium channel activity(GO:0005262)
4.0 11.9 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
3.9 31.5 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
3.9 31.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
3.7 63.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
3.7 37.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
3.5 10.6 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
3.4 17.2 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
3.4 10.3 GO:0031852 mu-type opioid receptor binding(GO:0031852)
3.4 24.0 GO:0004062 aryl sulfotransferase activity(GO:0004062)
3.4 27.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
3.3 16.7 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
3.3 46.4 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
3.3 19.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
3.2 19.1 GO:0030274 LIM domain binding(GO:0030274)
3.2 34.7 GO:0035613 RNA stem-loop binding(GO:0035613)
3.1 9.3 GO:0047522 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
3.1 70.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
3.0 9.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
3.0 174.9 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
3.0 81.1 GO:0043014 alpha-tubulin binding(GO:0043014)
2.8 39.8 GO:0042043 neurexin family protein binding(GO:0042043)
2.7 29.8 GO:0051378 serotonin binding(GO:0051378)
2.7 8.0 GO:0016015 morphogen activity(GO:0016015)
2.5 48.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
2.5 10.0 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
2.5 9.9 GO:0005136 interleukin-4 receptor binding(GO:0005136)
2.5 17.3 GO:0002151 G-quadruplex RNA binding(GO:0002151)
2.5 9.9 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
2.4 22.0 GO:0045499 chemorepellent activity(GO:0045499)
2.4 70.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
2.4 19.4 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
2.3 7.0 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
2.3 99.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
2.3 46.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
2.2 62.2 GO:0042056 chemoattractant activity(GO:0042056)
2.2 211.9 GO:0004860 protein kinase inhibitor activity(GO:0004860)
2.2 15.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
2.2 39.3 GO:0005523 tropomyosin binding(GO:0005523)
2.2 54.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
2.1 29.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
2.1 6.3 GO:0070052 collagen V binding(GO:0070052)
2.0 10.2 GO:0001729 ceramide kinase activity(GO:0001729)
2.0 18.0 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
2.0 35.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
2.0 56.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
1.9 28.8 GO:0008409 5'-3' exonuclease activity(GO:0008409)
1.9 41.4 GO:0005112 Notch binding(GO:0005112)
1.9 167.1 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
1.8 25.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
1.8 9.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
1.8 28.8 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
1.8 23.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
1.8 24.8 GO:0043422 protein kinase B binding(GO:0043422)
1.7 10.4 GO:0035033 histone deacetylase regulator activity(GO:0035033)
1.7 86.8 GO:0048365 Rac GTPase binding(GO:0048365)
1.7 25.1 GO:0005540 hyaluronic acid binding(GO:0005540)
1.6 96.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
1.6 7.9 GO:1990715 mRNA CDS binding(GO:1990715)
1.5 35.3 GO:0017091 AU-rich element binding(GO:0017091)
1.5 16.4 GO:0035198 miRNA binding(GO:0035198)
1.5 7.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
1.5 11.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
1.4 18.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
1.4 30.7 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
1.4 11.1 GO:0008432 JUN kinase binding(GO:0008432)
1.4 52.4 GO:0050840 extracellular matrix binding(GO:0050840)
1.4 11.0 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
1.3 18.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
1.3 118.7 GO:0044325 ion channel binding(GO:0044325)
1.3 32.1 GO:0003785 actin monomer binding(GO:0003785)
1.3 67.4 GO:0005080 protein kinase C binding(GO:0005080)
1.3 812.7 GO:0005509 calcium ion binding(GO:0005509)
1.3 6.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
1.3 27.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
1.2 15.7 GO:0071837 HMG box domain binding(GO:0071837)
1.2 4.8 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
1.2 25.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
1.2 39.8 GO:0001540 beta-amyloid binding(GO:0001540)
1.1 17.5 GO:0000146 microfilament motor activity(GO:0000146)
1.0 13.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
1.0 277.8 GO:0030695 GTPase regulator activity(GO:0030695)
1.0 8.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
1.0 23.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
1.0 14.1 GO:0033038 bitter taste receptor activity(GO:0033038)
1.0 4.9 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
1.0 6.7 GO:0019808 polyamine binding(GO:0019808)
0.9 45.5 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.9 9.2 GO:0048018 receptor agonist activity(GO:0048018)
0.9 4.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.9 29.1 GO:0005109 frizzled binding(GO:0005109)
0.9 48.0 GO:0046332 SMAD binding(GO:0046332)
0.9 21.8 GO:0008483 transaminase activity(GO:0008483)
0.8 89.8 GO:0051015 actin filament binding(GO:0051015)
0.8 7.2 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.8 4.0 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.8 11.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.8 6.1 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.8 20.4 GO:0009055 electron carrier activity(GO:0009055)
0.7 22.8 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.7 5.8 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.7 65.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.7 511.0 GO:0042803 protein homodimerization activity(GO:0042803)
0.7 11.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.7 6.0 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.6 4.4 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.6 21.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.6 9.3 GO:0050681 androgen receptor binding(GO:0050681)
0.6 5.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.6 10.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.6 4.4 GO:0030983 mismatched DNA binding(GO:0030983)
0.5 77.7 GO:0000287 magnesium ion binding(GO:0000287)
0.5 92.8 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.5 13.2 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.5 1.9 GO:0004594 pantothenate kinase activity(GO:0004594)
0.4 4.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.4 29.4 GO:0030165 PDZ domain binding(GO:0030165)
0.4 15.1 GO:0032934 sterol binding(GO:0032934)
0.4 39.2 GO:0016503 pheromone receptor activity(GO:0016503)
0.4 3.5 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.4 1.9 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.4 3.0 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.4 12.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.4 1.8 GO:0070728 leucine binding(GO:0070728)
0.3 7.9 GO:0004407 histone deacetylase activity(GO:0004407)
0.3 6.9 GO:0030506 ankyrin binding(GO:0030506)
0.3 6.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.3 7.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.3 12.2 GO:0003774 motor activity(GO:0003774)
0.3 18.0 GO:0017137 Rab GTPase binding(GO:0017137)
0.3 12.7 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.3 18.4 GO:0002020 protease binding(GO:0002020)
0.3 6.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 8.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.2 63.5 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.2 27.7 GO:0016874 ligase activity(GO:0016874)
0.2 0.3 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.2 1.9 GO:0051011 microtubule minus-end binding(GO:0051011)
0.2 42.7 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.2 10.1 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.1 2.0 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 28.3 GO:0015631 tubulin binding(GO:0015631)
0.1 0.4 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.1 1.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.5 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 1.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 19.6 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 99.7 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
3.8 97.9 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
3.4 133.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
3.1 90.2 PID MYC PATHWAY C-MYC pathway
3.1 210.1 PID LKB1 PATHWAY LKB1 signaling events
3.1 49.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
3.0 42.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
3.0 145.6 NABA COLLAGENS Genes encoding collagen proteins
3.0 41.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
2.9 113.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
2.7 192.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
2.4 40.9 PID LPA4 PATHWAY LPA4-mediated signaling events
2.4 88.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
2.3 65.8 PID EPHA FWDPATHWAY EPHA forward signaling
2.2 67.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
2.1 92.9 PID ATR PATHWAY ATR signaling pathway
2.1 74.7 SIG CD40PATHWAYMAP Genes related to CD40 signaling
2.0 50.9 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
2.0 66.6 PID CDC42 PATHWAY CDC42 signaling events
1.9 83.8 PID RAC1 PATHWAY RAC1 signaling pathway
1.9 53.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
1.9 37.6 PID GLYPICAN 1PATHWAY Glypican 1 network
1.9 41.0 PID NETRIN PATHWAY Netrin-mediated signaling events
1.7 50.6 PID NCADHERIN PATHWAY N-cadherin signaling events
1.7 11.9 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
1.6 98.7 PID NOTCH PATHWAY Notch signaling pathway
1.5 15.4 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
1.4 42.9 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
1.4 22.0 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
1.3 82.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
1.2 37.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
1.2 29.2 ST G ALPHA I PATHWAY G alpha i Pathway
1.1 20.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.8 13.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.8 234.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.7 5.0 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.7 23.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.7 28.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.7 104.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.7 9.3 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.6 24.2 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.5 24.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.4 8.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.4 10.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.3 9.7 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.2 11.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 6.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.2 7.7 PID P53 REGULATION PATHWAY p53 pathway
0.2 0.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 3.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.3 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
22.8 638.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
22.8 387.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
21.4 342.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
10.1 140.8 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
9.6 336.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
8.4 117.5 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
7.8 47.0 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
7.7 207.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
7.4 51.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
6.8 148.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
6.7 153.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
6.4 83.0 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
5.6 67.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
5.0 80.8 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
5.0 124.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
4.5 134.6 REACTOME MYOGENESIS Genes involved in Myogenesis
4.5 13.5 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
4.3 55.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
4.1 49.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
3.9 97.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
3.9 66.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
3.8 107.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
3.8 191.2 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
3.8 83.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
3.8 15.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
3.8 184.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
3.6 115.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
3.5 74.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
3.5 76.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
3.4 48.0 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
3.3 192.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
3.1 56.2 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
3.0 38.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
2.9 72.1 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
2.8 158.2 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
2.7 161.4 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
2.6 247.7 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
2.6 47.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
2.4 31.0 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
2.3 158.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
2.2 82.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
2.1 66.8 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
1.9 18.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
1.8 47.0 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
1.7 29.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
1.7 63.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
1.6 26.2 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
1.6 27.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
1.5 39.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
1.4 70.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
1.3 41.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
1.2 31.5 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
1.2 21.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
1.2 40.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.9 16.0 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.9 13.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.9 22.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.8 10.0 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.8 10.6 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.8 7.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.8 46.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.7 11.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.7 15.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.7 44.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.6 16.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.6 6.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.5 31.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.5 16.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.4 4.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.4 15.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.4 3.0 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.4 7.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.3 7.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.3 9.3 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.3 4.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.2 54.4 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.2 11.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.2 5.0 REACTOME ORC1 REMOVAL FROM CHROMATIN Genes involved in Orc1 removal from chromatin
0.2 1.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2 14.6 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.1 6.2 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.1 4.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 0.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 0.4 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 2.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.9 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.8 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation