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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Hoxa2

Z-value: 1.45

Motif logo

Transcription factors associated with Hoxa2

Gene Symbol Gene ID Gene Info

Activity profile of Hoxa2 motif

Sorted Z-values of Hoxa2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_3293599 81.87 ENSRNOT00000081999
ENSRNOT00000047118
ENSRNOT00000020427
ELKS/RAB6-interacting/CAST family member 2
chr3_-_45169118 37.24 ENSRNOT00000086371
coiled-coil domain containing 148
chr10_-_96131880 37.01 ENSRNOT00000004578
calcium voltage-gated channel auxiliary subunit gamma 5
chr6_+_132242328 36.94 ENSRNOT00000081088
cytochrome P450, family 46, subfamily a, polypeptide 1
chr3_+_159368273 36.67 ENSRNOT00000041688
serum/glucocorticoid regulated kinase 2
chr9_-_89193821 36.59 ENSRNOT00000090881
SPHK1 interactor, AKAP domain containing
chr16_-_7007051 32.80 ENSRNOT00000023984
inter-alpha trypsin inhibitor, heavy chain 3
chr2_+_228544418 32.62 ENSRNOT00000013030
translocation associated membrane protein 1-like 1
chr11_+_80358211 32.46 ENSRNOT00000002519
somatostatin
chr4_-_184096806 30.77 ENSRNOT00000055433
mKIAA1238 protein-like
chr6_-_86223052 30.25 ENSRNOT00000046828
fibrous sheath CABYR binding protein
chr17_+_9746485 29.86 ENSRNOT00000072298
profilin 3
chr17_-_43584152 29.36 ENSRNOT00000023241
solute carrier family 17, member 2
chr17_+_23661429 28.36 ENSRNOT00000046523
phosphatase and actin regulator 1
chr6_-_23291568 28.08 ENSRNOT00000085708
CAP-GLY domain containing linker protein family, member 4
chr9_+_95501778 26.74 ENSRNOT00000086805
secreted phosphoprotein 2
chr1_+_101161252 26.50 ENSRNOT00000028064
ENSRNOT00000064184
solute carrier family 17 member 7
chr1_+_150310319 26.46 ENSRNOT00000042081
olfactory receptor 34
chr1_+_219964429 26.43 ENSRNOT00000088288
spectrin, beta, non-erythrocytic 2
chr17_+_88215834 26.37 ENSRNOT00000034098
G protein-coupled receptor 158
chr16_+_34795971 26.35 ENSRNOT00000043510
myeloid-associated differentiation marker-like
chr2_+_147496229 25.88 ENSRNOT00000022105
transmembrane 4 L six family member 4
chr7_+_20262680 25.39 ENSRNOT00000046378
similar to hypothetical protein 4930509O22
chr4_+_22859622 24.78 ENSRNOT00000073501
ENSRNOT00000068410
ADAM metallopeptidase domain 22
chr6_+_113898420 24.38 ENSRNOT00000064872
neurexin 3
chrX_-_142248369 24.16 ENSRNOT00000091330
fibroblast growth factor 13
chr9_-_89195273 24.03 ENSRNOT00000022281
SPHK1 interactor, AKAP domain containing
chr1_+_229063714 24.03 ENSRNOT00000087526
glycine-N-acyltransferase
chr1_-_67094567 23.17 ENSRNOT00000073583

chr14_+_22517774 22.38 ENSRNOT00000047655
UDP-glucuronosyltransferase 2 family, member 37
chr16_-_75156321 22.33 ENSRNOT00000058063
defensin beta 11
chr7_-_136853957 22.31 ENSRNOT00000008985
neural EGFL like 2
chr6_+_26797126 21.83 ENSRNOT00000010586
cell growth regulator with EF hand domain 1
chr10_-_8498422 21.78 ENSRNOT00000082332
RNA binding protein, fox-1 homolog 1
chr9_-_4879755 21.72 ENSRNOT00000047615
similar to Sulfotransferase K1 (rSULT1C2)
chrX_-_1848904 21.71 ENSRNOT00000010984
regucalcin
chr9_+_4094995 21.67 ENSRNOT00000089450
sulfotransferase 1C2-like
chr13_+_24823488 21.38 ENSRNOT00000019907
cadherin 20
chrX_-_38468360 20.76 ENSRNOT00000045285
MAP7 domain containing 2
chr8_-_8524643 20.50 ENSRNOT00000009418
contactin 5
chr7_-_100382897 20.37 ENSRNOT00000006510
LOC500876
chr19_+_15294248 20.31 ENSRNOT00000024622
carboxylesterase 1F
chr19_+_6046665 20.06 ENSRNOT00000084126
cadherin 8
chr6_+_112203679 19.98 ENSRNOT00000031205
neurexin 3
chr4_-_155275161 19.94 ENSRNOT00000032690
ribosomal modification protein rimK-like family member B
chr2_-_183210799 19.83 ENSRNOT00000085382
tripartite motif-containing 2
chr1_-_227392054 19.70 ENSRNOT00000054806
membrane-spanning 4-domains, subfamily A, member 13, pseudogene 1
chr20_+_20236151 19.68 ENSRNOT00000079630
ankyrin 3
chrX_+_82143789 19.52 ENSRNOT00000003724
POU class 3 homeobox 4
chr8_-_80631873 18.60 ENSRNOT00000091661
ENSRNOT00000080662
unc-13 homolog C
chr19_+_25983169 18.50 ENSRNOT00000004404
synaptonemal complex central element protein 2
chr7_-_106753592 18.47 ENSRNOT00000006930
potassium voltage-gated channel subfamily Q member 3
chr13_+_77485113 18.44 ENSRNOT00000080254
tenascin R
chr20_-_54517709 18.25 ENSRNOT00000076234
glutamate ionotropic receptor kainate type subunit 2
chr5_-_166116516 18.17 ENSRNOT00000079919
ENSRNOT00000080888
kinesin family member 1B
chr1_+_1702696 17.93 ENSRNOT00000019181
LDL receptor related protein 11
chr16_+_56247659 17.93 ENSRNOT00000017452
tumor suppressor candidate 3
chr7_+_123482255 17.90 ENSRNOT00000064487
hypothetical protein LOC688613
chr7_+_34402738 17.77 ENSRNOT00000030985
coiled-coil domain containing 38
chr8_+_41657566 17.62 ENSRNOT00000042860
urinary protein 2
chr6_+_64808238 17.62 ENSRNOT00000093195
neuronal cell adhesion molecule
chr5_+_122390522 17.57 ENSRNOT00000064567
SH3-domain GRB2-like (endophilin) interacting protein 1
chr16_-_74330911 17.55 ENSRNOT00000084330
solute carrier family 20 member 2
chr1_-_67134827 17.51 ENSRNOT00000045214
vomeronasal 1 receptor 45
chr3_+_69549673 17.35 ENSRNOT00000043974
zinc finger protein 804A
chr2_-_173563273 17.24 ENSRNOT00000081423
zinc finger, B-box domain containing
chr4_+_96831880 17.19 ENSRNOT00000068400
RSA-14-44 protein
chr7_+_20462081 16.75 ENSRNOT00000088383

chr10_+_1920529 16.65 ENSRNOT00000072296
RIKEN cDNA A630010A05 gene
chr4_+_138269142 16.62 ENSRNOT00000007788
contactin 4
chr2_-_210738378 16.40 ENSRNOT00000025746
glutathione S-transferase, mu 6
chr9_-_4327679 16.25 ENSRNOT00000073468
sulfotransferase 1C1-like
chr15_-_6587367 16.11 ENSRNOT00000038449
zinc finger protein 385D
chr9_+_8399632 16.10 ENSRNOT00000092165
hypothetical protein LOC100360856
chr6_+_97168453 15.83 ENSRNOT00000085790
synaptotagmin 16
chr4_+_30313102 15.81 ENSRNOT00000012657
ankyrin repeat and SOCS box-containing 4
chr9_+_118849302 15.79 ENSRNOT00000087592
DLG associated protein 1
chr6_+_10483308 15.76 ENSRNOT00000074516
transmembrane protein 247
chr12_+_7502925 15.75 ENSRNOT00000072801
katanin p60 ATPase-containing subunit A-like 1-like
chr5_-_146446227 15.60 ENSRNOT00000044868
high-mobility group box 4
chr17_-_71897972 15.58 ENSRNOT00000065942
Scm-like with four mbt domains 2
chr3_-_158328881 15.52 ENSRNOT00000044466
protein tyrosine phosphatase, receptor type, T
chr11_-_81735592 15.45 ENSRNOT00000078203
alpha-2-HS-glycoprotein
chr19_-_59991590 15.40 ENSRNOT00000091620

chr18_+_61563053 15.39 ENSRNOT00000022845
gastrin releasing peptide
chr5_+_124476168 15.27 ENSRNOT00000077754
similar to novel protein
chr4_-_117589464 15.20 ENSRNOT00000021167
N-acetyltransferase 8 (GCN5-related) family member 1
chrX_+_105134498 15.16 ENSRNOT00000002058
transmembrane protein 35
chr19_+_24545318 15.04 ENSRNOT00000005071
calmegin
chr5_+_10178302 14.92 ENSRNOT00000009679
syntrophin, gamma 1
chr9_+_73378057 14.92 ENSRNOT00000043627
ENSRNOT00000045766
ENSRNOT00000092445
ENSRNOT00000037974
microtubule-associated protein 2
chr3_+_40038336 14.70 ENSRNOT00000048804
polypeptide N-acetylgalactosaminyltransferase 13
chr2_+_114413410 14.69 ENSRNOT00000015866
solute carrier family 2 member 2
chr7_-_124929025 14.69 ENSRNOT00000015447
EF-hand calcium binding domain 6
chr14_+_22724399 14.57 ENSRNOT00000002724
UDP glucuronosyltransferase 2 family, polypeptide B10
chr1_+_125367280 14.45 ENSRNOT00000022049
amyloid beta precursor protein binding family A member 2
chr9_+_4817854 14.42 ENSRNOT00000040879
sulfotransferase 1C2-like
chr1_-_215838209 14.12 ENSRNOT00000050760
insulin-like growth factor 2
chr2_+_78247448 14.09 ENSRNOT00000089805
protein FAM134B
chr4_+_64088900 14.08 ENSRNOT00000075341
cholinergic receptor, muscarinic 2
chr4_+_122217505 14.02 ENSRNOT00000030426
hypothetical protein LOC685964
chr1_-_224533219 13.96 ENSRNOT00000051289
integral membrane transport protein UST5r
chr12_-_52124779 13.89 ENSRNOT00000088839
polypeptide N-acetylgalactosaminyltransferase 9
chr9_+_73319710 13.87 ENSRNOT00000092485
microtubule-associated protein 2
chr7_-_130827152 13.85 ENSRNOT00000019406
synaptotagmin 10
chr6_+_64297888 13.81 ENSRNOT00000050222
ENSRNOT00000083088
ENSRNOT00000093147
neuronal cell adhesion molecule
chrX_-_15707436 13.74 ENSRNOT00000085907
synaptophysin
chr2_+_237679792 13.73 ENSRNOT00000064628
GIMAP family P-loop NTPase domain containing 1
chr9_-_91683468 13.67 ENSRNOT00000041550
phosphotyrosine interaction domain containing 1
chr14_-_46054022 13.52 ENSRNOT00000002982
similar to RIKEN cDNA 0610040J01
chr1_-_260992291 13.42 ENSRNOT00000035415
ENSRNOT00000034758
slit guidance ligand 1
chr3_+_148790979 13.37 ENSRNOT00000085757
kinesin family member 3B
chr17_+_43458553 13.36 ENSRNOT00000088939
solute carrier family 17, member 4
chr1_+_83714347 13.28 ENSRNOT00000085245
cytochrome P450, family 2, subfamily a, polypeptide 1
chr18_-_51651267 13.19 ENSRNOT00000020325
aldehyde dehydrogenase 7 family, member A1
chr9_+_8349033 13.06 ENSRNOT00000073775
hypothetical protein LOC100360856
chrX_-_115175299 13.02 ENSRNOT00000074322
doublecortin
chr17_-_48562838 13.00 ENSRNOT00000017102
ENSRNOT00000084702
amphiphysin
chr11_+_20474483 12.99 ENSRNOT00000082417
ENSRNOT00000002895
neural cell adhesion molecule 2
chr4_+_52129556 12.98 ENSRNOT00000009435
hyaluronoglucosaminidase 6
chr9_+_4731914 12.97 ENSRNOT00000061893

chr5_+_124021366 12.97 ENSRNOT00000009977
DAB1, reelin adaptor protein
chr13_-_42263024 12.65 ENSRNOT00000004741
Ly6/Plaur domain containing 1
chr19_-_62150423 12.63 ENSRNOT00000073524
ENSRNOT00000091209
coiled-coil domain containing 7
chr3_-_170040953 12.51 ENSRNOT00000005866
cerebellin 4 precursor
chr13_+_71331052 12.41 ENSRNOT00000075480
glutamate-ammonia ligase
chr18_-_15089988 12.37 ENSRNOT00000074116
meprin A subunit beta
chr9_-_4945352 12.30 ENSRNOT00000082530
sulfotransferase family 1C member 3
chr10_+_88356615 12.24 ENSRNOT00000022687
kelch-like family member 10
chr9_-_32868371 12.15 ENSRNOT00000038369
similar to chromosome 9 open reading frame 79
chr3_-_64543100 12.04 ENSRNOT00000025803
zinc finger protein 385B
chr5_-_134008255 12.04 ENSRNOT00000012448
cytochrome P450, family 4, subfamily a, polypeptide 8
chr19_-_50220455 11.98 ENSRNOT00000079760
short chain dehydrogenase/reductase family 42E, member 1
chr8_-_40883880 11.90 ENSRNOT00000075593
disks large homolog 5-like
chr20_-_45024315 11.88 ENSRNOT00000066856
similar to Na+ dependent glucose transporter 1
chr8_+_117906014 11.81 ENSRNOT00000056180
serine peptidase inhibitor, Kazal type 8
chr10_+_103992309 11.75 ENSRNOT00000065292
tripartite motif protein 80
chr13_-_51076852 11.72 ENSRNOT00000078993
adenosine A1 receptor
chr4_-_159192526 11.65 ENSRNOT00000026731
potassium voltage-gated channel subfamily A member 1
chr11_+_30363280 11.59 ENSRNOT00000002885
superoxide dismutase 1, soluble
chr7_-_141185710 11.55 ENSRNOT00000085033
Fas apoptotic inhibitory molecule 2
chr6_-_26445787 11.54 ENSRNOT00000084242
dihydropyrimidinase-related protein 5-like
chr1_+_189364288 11.53 ENSRNOT00000080338
acyl-CoA synthetase medium-chain family member 1
chr11_+_60102121 11.50 ENSRNOT00000045521
transmembrane protease, serine 7
chr12_+_30165694 11.37 ENSRNOT00000001211
argininosuccinate lyase
chr19_-_43841795 11.36 ENSRNOT00000079539
lactate dehydrogenase D
chr2_-_181531978 11.29 ENSRNOT00000072029
neuropeptide Y receptor Y2
chr3_+_65672058 11.28 ENSRNOT00000057901
similar to TF-1 apoptosis related protein 19
chr1_+_282568287 11.20 ENSRNOT00000015997
carboxylesterase 2I
chr17_-_57526461 11.20 ENSRNOT00000072723
ankyrin repeat domain-containing protein 26-like
chr1_-_224389389 11.18 ENSRNOT00000077408
ENSRNOT00000050010
integral membrane transport protein UST4r
chr9_+_12475006 11.11 ENSRNOT00000079703
uncharacterized LOC100912293
chr7_-_139063752 11.09 ENSRNOT00000072309
protein lifeguard 2-like
chr17_+_42133076 11.05 ENSRNOT00000031384
aldehyde dehydrogenase 5 family, member A1
chr9_+_10760113 11.03 ENSRNOT00000073054
arrestin domain containing 5
chr9_+_95309759 10.86 ENSRNOT00000051438
maestro heat-like repeat family member 2A
chr13_-_93307199 10.83 ENSRNOT00000065041
regulator of G-protein signaling 7
chr19_+_26106838 10.78 ENSRNOT00000035987
hook microtubule-tethering protein 2
chr6_-_133716847 10.75 ENSRNOT00000072399
retrotransposon-like 1
chr10_-_107539465 10.72 ENSRNOT00000004524
RNA binding protein, fox-1 homolog 3
chr2_-_235177275 10.71 ENSRNOT00000093153
uncharacterized LOC103691699
chr1_-_71710374 10.68 ENSRNOT00000078556
ENSRNOT00000046152
NLR family, pyrin domain containing 4
chr4_-_31730386 10.68 ENSRNOT00000013817
solute carrier family 25 member 13
chr1_-_148119857 10.65 ENSRNOT00000040325
Cytochrome P450, family 2, subfamily c, polypeptide 7-like
chrX_+_62282212 10.63 ENSRNOT00000039568

chr2_-_188645196 10.62 ENSRNOT00000083793
ephrin A3
chr13_-_37287458 10.59 ENSRNOT00000003391
insulin induced gene 2
chr3_+_117421604 10.58 ENSRNOT00000008860
ENSRNOT00000008857
solute carrier family 12 member 1
chr3_-_120373500 10.57 ENSRNOT00000067727
nephrocystin 1
chr2_+_68820615 10.55 ENSRNOT00000087007
ENSRNOT00000089504
epidermal growth factor
chr4_-_157294047 10.51 ENSRNOT00000005601
enolase 2
chr15_+_108608204 10.46 ENSRNOT00000018918
citrate lyase beta like
chr7_+_119647375 10.38 ENSRNOT00000046563
potassium channel tetramerization domain containing 17
chr9_+_35289443 10.37 ENSRNOT00000037765
ENSRNOT00000060503
SPATA31 subfamily E, member 1
chr10_+_34414854 10.25 ENSRNOT00000074980
similar to olfactory receptor 1394
chr2_-_172459165 10.22 ENSRNOT00000057473
schwannomin interacting protein 1
chr9_+_20251521 10.05 ENSRNOT00000005535
gamma-enolase-like
chr14_+_22072024 9.94 ENSRNOT00000002680
estrogen sulfotransferase
chr1_+_83163079 9.92 ENSRNOT00000077725
ENSRNOT00000034845
cytochrome P450, family 2, subfamily b, polypeptide 3
chr15_+_17775692 9.89 ENSRNOT00000061169
similar to RIKEN cDNA 4933406L09
chr7_-_93502571 9.83 ENSRNOT00000077033
ENSRNOT00000076080
sterile alpha motif domain containing 12
chr19_+_52258947 9.74 ENSRNOT00000021072
adenosine deaminase domain containing 2
chr3_+_75906945 9.73 ENSRNOT00000047110
olfactory receptor 586
chr1_-_189199376 9.68 ENSRNOT00000021027
uromodulin
chr8_+_53678994 9.67 ENSRNOT00000083419
dopamine receptor D2
chr1_+_98425903 9.67 ENSRNOT00000024170
hypothetical protein LOC690483
chr2_+_57276919 9.65 ENSRNOT00000063899
similar to hypothetical protein FLJ13231
chr4_+_149908375 9.64 ENSRNOT00000019504
uncharacterized LOC100909657
chr5_-_77749613 9.58 ENSRNOT00000075988
major urinary protein 5
chrX_-_42329232 9.53 ENSRNOT00000045705
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 4
chr16_+_48120864 9.42 ENSRNOT00000068562
storkhead box 2
chr17_+_56935451 9.39 ENSRNOT00000058966
similar to hypothetical protein 4930474N05
chr3_+_70327193 9.38 ENSRNOT00000089165
fibrous sheath-interacting protein 2
chr17_+_10586043 9.37 ENSRNOT00000023125
hypothetical LOC306766
chr7_-_107223047 9.33 ENSRNOT00000007250
ENSRNOT00000084875
leucine rich repeat containing 6
chr3_-_2444281 9.27 ENSRNOT00000013863
tubulin, beta 4B class IVb
chr3_+_63379031 9.22 ENSRNOT00000068199
oxysterol binding protein-like 6
chrX_-_107542510 9.21 ENSRNOT00000074140
RAB9B, member RAS oncogene family
chrX_+_71199491 9.21 ENSRNOT00000076168
ENSRNOT00000005077
ENSRNOT00000005102
neuroligin 3
chr11_-_81717521 9.15 ENSRNOT00000058422
alpha-2-HS-glycoprotein

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxa2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.2 21.7 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
6.6 26.5 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
5.9 23.8 GO:0019676 ammonia assimilation cycle(GO:0019676)
5.7 17.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
5.2 21.0 GO:0048252 lauric acid metabolic process(GO:0048252)
4.9 19.7 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
4.6 4.6 GO:0014736 negative regulation of muscle atrophy(GO:0014736)
4.6 13.7 GO:2000474 regulation of opioid receptor signaling pathway(GO:2000474)
4.4 17.5 GO:0044467 glial cell-derived neurotrophic factor secretion(GO:0044467) positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) negative regulation of dopamine receptor signaling pathway(GO:0060160) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
4.3 13.0 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
3.9 11.7 GO:0032900 regulation of nucleoside transport(GO:0032242) negative regulation of neurotrophin production(GO:0032900) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256) negative regulation of long term synaptic depression(GO:1900453)
3.9 11.6 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
3.7 11.2 GO:0016107 sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488)
3.6 18.2 GO:0019520 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
3.5 10.6 GO:0032978 protein insertion into membrane from inner side(GO:0032978)
3.5 10.6 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
3.5 31.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
3.5 24.2 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
3.4 13.7 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
3.4 13.4 GO:0021834 chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
3.1 18.4 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
2.9 14.7 GO:0015755 carbohydrate utilization(GO:0009758) fructose transport(GO:0015755)
2.9 17.6 GO:2000253 positive regulation of feeding behavior(GO:2000253)
2.9 11.6 GO:1904823 purine nucleobase transmembrane transport(GO:1904823)
2.9 34.5 GO:0016081 synaptic vesicle docking(GO:0016081)
2.8 8.5 GO:0021627 muscle attachment(GO:0016203) olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
2.8 14.1 GO:0061709 reticulophagy(GO:0061709)
2.8 14.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
2.7 10.7 GO:0043490 malate-aspartate shuttle(GO:0043490)
2.7 18.6 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
2.6 36.9 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
2.6 20.5 GO:0090394 negative regulation of excitatory postsynaptic potential(GO:0090394)
2.6 7.7 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
2.5 39.6 GO:0051923 sulfation(GO:0051923)
2.4 9.7 GO:0072218 ascending thin limb development(GO:0072021) metanephric ascending thin limb development(GO:0072218)
2.4 43.4 GO:0090129 positive regulation of synapse maturation(GO:0090129)
2.3 11.6 GO:0050975 sensory perception of touch(GO:0050975)
2.3 20.6 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
2.2 6.7 GO:0006083 acetate metabolic process(GO:0006083)
2.2 6.6 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
2.1 6.4 GO:0042412 taurine biosynthetic process(GO:0042412)
2.1 6.4 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
2.1 6.4 GO:0010034 response to acetate(GO:0010034)
2.1 6.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
2.0 12.2 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
2.0 14.1 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
2.0 10.1 GO:0002003 angiotensin maturation(GO:0002003)
2.0 46.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
2.0 15.8 GO:0070842 aggresome assembly(GO:0070842)
2.0 7.9 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
1.9 13.3 GO:0009804 coumarin metabolic process(GO:0009804)
1.9 7.6 GO:0051692 cellular oligosaccharide catabolic process(GO:0051692) regulation of exo-alpha-sialidase activity(GO:1903015)
1.9 17.0 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
1.9 61.7 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
1.9 5.6 GO:0090370 lysophospholipid transport(GO:0051977) negative regulation of cholesterol efflux(GO:0090370)
1.9 7.5 GO:0016098 monoterpenoid metabolic process(GO:0016098)
1.9 22.3 GO:0070050 development of secondary female sexual characteristics(GO:0046543) neuron cellular homeostasis(GO:0070050)
1.9 37.0 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
1.8 5.4 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
1.8 5.4 GO:0072720 response to dithiothreitol(GO:0072720)
1.8 7.0 GO:1904008 response to monosodium glutamate(GO:1904008)
1.7 10.3 GO:0097688 glutamate receptor clustering(GO:0097688)
1.7 5.0 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
1.7 6.6 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
1.6 13.2 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
1.6 4.9 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
1.5 4.6 GO:0060082 eye blink reflex(GO:0060082)
1.5 10.5 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
1.4 9.6 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
1.4 6.8 GO:1904970 brush border assembly(GO:1904970)
1.3 8.0 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
1.3 15.8 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
1.3 26.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
1.3 19.5 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
1.3 3.9 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) formamide metabolic process(GO:0043606)
1.3 17.9 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
1.3 25.4 GO:0006544 glycine metabolic process(GO:0006544)
1.3 3.8 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
1.3 5.0 GO:0060005 vestibular reflex(GO:0060005)
1.2 8.7 GO:0022605 oogenesis stage(GO:0022605)
1.2 11.2 GO:0015747 urate transport(GO:0015747)
1.2 3.7 GO:1901091 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
1.2 15.7 GO:0051013 microtubule severing(GO:0051013)
1.2 4.8 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
1.2 6.0 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
1.2 9.7 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509)
1.2 15.6 GO:0006817 phosphate ion transport(GO:0006817)
1.2 9.5 GO:0007262 STAT protein import into nucleus(GO:0007262)
1.2 4.7 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
1.2 10.5 GO:0071501 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
1.2 3.5 GO:0033869 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
1.2 18.5 GO:0060081 membrane hyperpolarization(GO:0060081)
1.1 4.5 GO:0061615 glycolytic process through fructose-6-phosphate(GO:0061615)
1.1 32.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
1.1 30.5 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
1.1 32.5 GO:0010447 response to acidic pH(GO:0010447)
1.1 24.6 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
1.1 7.7 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
1.1 6.6 GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051343)
1.1 7.7 GO:0033572 transferrin transport(GO:0033572)
1.1 16.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
1.1 4.3 GO:0007386 compartment pattern specification(GO:0007386)
1.1 4.2 GO:0010958 regulation of amino acid import(GO:0010958)
1.0 5.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
1.0 3.1 GO:0048749 compound eye development(GO:0048749)
1.0 6.1 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
1.0 6.0 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
1.0 3.0 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
1.0 3.9 GO:0031179 peptide modification(GO:0031179)
0.9 13.0 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.9 1.8 GO:0009644 response to high light intensity(GO:0009644)
0.9 3.6 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.9 2.7 GO:0006574 valine catabolic process(GO:0006574)
0.9 7.1 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.9 28.8 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.9 13.1 GO:0042407 cristae formation(GO:0042407)
0.9 11.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.8 6.5 GO:0070417 cellular response to cold(GO:0070417)
0.8 2.4 GO:0015965 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966) basophil activation(GO:0045575)
0.8 17.7 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.8 3.0 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.8 2.3 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.8 3.8 GO:0031296 cobalamin transport(GO:0015889) B cell costimulation(GO:0031296)
0.7 3.0 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.7 12.6 GO:1905145 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.7 2.2 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.7 5.9 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.7 2.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.7 11.5 GO:0021681 cerebellar granular layer development(GO:0021681)
0.7 7.9 GO:0046069 cGMP catabolic process(GO:0046069)
0.7 4.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.7 9.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.7 2.1 GO:0007403 glial cell fate determination(GO:0007403)
0.7 2.0 GO:0006214 thymidine catabolic process(GO:0006214) pyrimidine deoxyribonucleoside catabolic process(GO:0046127)
0.7 21.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.7 3.3 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.6 7.1 GO:0008090 retrograde axonal transport(GO:0008090)
0.6 101.7 GO:0007416 synapse assembly(GO:0007416)
0.6 7.1 GO:0033141 regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141) serine phosphorylation of STAT protein(GO:0042501)
0.6 5.7 GO:0007000 nucleolus organization(GO:0007000)
0.6 4.4 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.6 5.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.6 11.8 GO:1902572 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.6 1.8 GO:1990168 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.6 8.9 GO:0051639 actin filament network formation(GO:0051639)
0.6 5.3 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.6 4.7 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.6 1.7 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.6 29.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.5 7.1 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.5 6.3 GO:0036159 inner dynein arm assembly(GO:0036159)
0.5 7.9 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.5 13.0 GO:0007413 axonal fasciculation(GO:0007413)
0.5 8.7 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.5 10.2 GO:0008210 estrogen metabolic process(GO:0008210)
0.5 2.0 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.5 3.9 GO:0061635 regulation of protein complex stability(GO:0061635)
0.5 5.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.5 1.9 GO:2000074 regulation of type B pancreatic cell development(GO:2000074) negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.5 5.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.5 2.4 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.5 10.4 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.4 4.9 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.4 8.5 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.4 8.0 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.4 2.2 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.4 15.0 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.4 2.5 GO:0038161 prolactin signaling pathway(GO:0038161)
0.4 21.9 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.4 33.7 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.4 8.6 GO:0032098 regulation of appetite(GO:0032098)
0.4 3.9 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.4 1.6 GO:0015879 carnitine transport(GO:0015879)
0.4 2.7 GO:0016576 histone dephosphorylation(GO:0016576)
0.4 3.8 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.4 1.9 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.4 10.6 GO:0016079 synaptic vesicle exocytosis(GO:0016079)
0.4 6.1 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.4 4.0 GO:0045056 transcytosis(GO:0045056)
0.4 38.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.4 6.0 GO:0043248 proteasome assembly(GO:0043248)
0.4 13.0 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.3 20.2 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.3 14.3 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.3 5.4 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.3 6.0 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.3 13.8 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.3 7.9 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.3 2.9 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.3 10.6 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.3 8.9 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.3 7.6 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.3 2.5 GO:0051665 membrane raft localization(GO:0051665)
0.3 2.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.3 3.6 GO:0007035 vacuolar acidification(GO:0007035)
0.3 0.6 GO:0097327 response to antineoplastic agent(GO:0097327)
0.3 6.3 GO:0006541 glutamine metabolic process(GO:0006541)
0.3 8.0 GO:1901998 toxin transport(GO:1901998)
0.3 2.6 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.3 4.5 GO:0007616 long-term memory(GO:0007616)
0.3 0.8 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.3 2.0 GO:0035881 amacrine cell differentiation(GO:0035881)
0.3 10.1 GO:0035902 response to immobilization stress(GO:0035902)
0.3 1.9 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.3 6.5 GO:0031572 mitotic G2 DNA damage checkpoint(GO:0007095) G2 DNA damage checkpoint(GO:0031572)
0.3 25.2 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.3 3.2 GO:0048672 bleb assembly(GO:0032060) positive regulation of collateral sprouting(GO:0048672)
0.3 4.0 GO:0044458 motile cilium assembly(GO:0044458)
0.2 34.7 GO:0007411 axon guidance(GO:0007411)
0.2 3.2 GO:0019532 oxalate transport(GO:0019532)
0.2 3.5 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.2 0.7 GO:0072695 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.2 6.5 GO:0008347 glial cell migration(GO:0008347)
0.2 5.0 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.2 9.7 GO:0016126 sterol biosynthetic process(GO:0016126)
0.2 5.2 GO:0071450 cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451)
0.2 6.9 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.2 22.4 GO:0030308 negative regulation of cell growth(GO:0030308)
0.2 0.6 GO:0034757 negative regulation of iron ion transport(GO:0034757)
0.2 2.8 GO:0036065 fucosylation(GO:0036065)
0.2 3.6 GO:0097503 sialylation(GO:0097503)
0.2 7.2 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.2 6.2 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.2 8.1 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.2 4.1 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.2 5.6 GO:0035418 protein localization to synapse(GO:0035418)
0.2 235.7 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.2 0.9 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.2 8.1 GO:0046849 bone remodeling(GO:0046849)
0.2 6.5 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.2 11.5 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.2 8.0 GO:0032106 positive regulation of macroautophagy(GO:0016239) positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.2 12.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.2 4.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.2 1.0 GO:1903541 regulation of exosomal secretion(GO:1903541)
0.2 18.7 GO:0007605 sensory perception of sound(GO:0007605)
0.2 1.8 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.2 29.9 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.1 0.9 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 4.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 2.4 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.1 1.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.4 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 4.9 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 0.6 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 2.0 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 0.4 GO:0046368 GDP-L-fucose biosynthetic process(GO:0042350) GDP-L-fucose metabolic process(GO:0046368)
0.1 9.5 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.1 8.0 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 5.5 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.1 19.4 GO:0072659 protein localization to plasma membrane(GO:0072659)
0.1 2.7 GO:0008333 endosome to lysosome transport(GO:0008333)
0.1 4.3 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 0.8 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.1 2.9 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 1.2 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 4.1 GO:0009142 nucleoside triphosphate biosynthetic process(GO:0009142)
0.1 0.4 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628)
0.1 0.5 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.1 4.0 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 0.7 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 0.2 GO:1904720 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721) negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
0.1 0.6 GO:0046519 sphingoid metabolic process(GO:0046519)
0.1 1.5 GO:0001893 maternal placenta development(GO:0001893)
0.0 1.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.5 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.8 GO:0042993 positive regulation of transcription factor import into nucleus(GO:0042993)
0.0 5.9 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 5.9 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 2.2 GO:0030316 osteoclast differentiation(GO:0030316)
0.0 0.2 GO:0018377 N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377)
0.0 0.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 1.7 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.5 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 3.6 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.7 GO:0070207 protein homotrimerization(GO:0070207)
0.0 3.2 GO:0006790 sulfur compound metabolic process(GO:0006790)
0.0 0.2 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.4 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.8 GO:0032543 mitochondrial translation(GO:0032543)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 18.4 GO:0072534 perineuronal net(GO:0072534)
3.5 10.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
3.4 20.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
3.4 10.3 GO:0098982 glycine-gated chloride channel complex(GO:0016935) GABA-ergic synapse(GO:0098982)
3.3 26.7 GO:0044305 calyx of Held(GO:0044305)
3.2 28.8 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
3.0 18.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
2.8 14.2 GO:0070695 FHF complex(GO:0070695)
2.7 69.6 GO:0043194 axon initial segment(GO:0043194)
2.7 13.4 GO:0016939 kinesin II complex(GO:0016939)
2.7 26.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
2.6 23.1 GO:0008091 spectrin(GO:0008091)
2.3 14.1 GO:0032280 symmetric synapse(GO:0032280)
2.3 7.0 GO:0005899 insulin receptor complex(GO:0005899)
2.0 18.2 GO:0071821 FANCM-MHF complex(GO:0071821)
2.0 15.8 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
2.0 110.5 GO:0048786 presynaptic active zone(GO:0048786)
1.9 13.1 GO:0061617 MICOS complex(GO:0061617)
1.8 30.3 GO:0035686 sperm fibrous sheath(GO:0035686)
1.6 6.5 GO:0031021 interphase microtubule organizing center(GO:0031021)
1.6 21.1 GO:0000801 central element(GO:0000801)
1.6 6.3 GO:0036156 inner dynein arm(GO:0036156)
1.5 15.0 GO:0001772 immunological synapse(GO:0001772)
1.4 7.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
1.4 21.2 GO:0043083 synaptic cleft(GO:0043083)
1.2 37.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
1.2 5.9 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
1.2 17.6 GO:0030122 AP-2 adaptor complex(GO:0030122)
1.0 11.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
1.0 8.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.9 11.4 GO:0070852 cell body fiber(GO:0070852)
0.8 11.6 GO:0033270 paranode region of axon(GO:0033270) juxtaparanode region of axon(GO:0044224)
0.7 12.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.7 3.6 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.7 11.6 GO:0031045 dense core granule(GO:0031045)
0.7 4.8 GO:0031595 nuclear proteasome complex(GO:0031595)
0.7 6.0 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.7 7.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.6 6.2 GO:0070187 telosome(GO:0070187)
0.6 34.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.6 7.9 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.6 10.5 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.5 10.8 GO:0044292 dendrite terminus(GO:0044292)
0.5 7.9 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.5 23.4 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.5 20.2 GO:0035869 ciliary transition zone(GO:0035869)
0.5 9.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.5 32.8 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.5 8.5 GO:0001520 outer dense fiber(GO:0001520)
0.5 10.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.5 9.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.4 3.3 GO:0000243 commitment complex(GO:0000243)
0.4 9.2 GO:0060077 inhibitory synapse(GO:0060077)
0.4 8.9 GO:0005865 striated muscle thin filament(GO:0005865)
0.4 1.9 GO:0005726 perichromatin fibrils(GO:0005726)
0.4 3.5 GO:0030314 junctional membrane complex(GO:0030314)
0.4 3.0 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.4 5.0 GO:0032426 stereocilium tip(GO:0032426)
0.3 2.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.3 2.0 GO:0090543 Flemming body(GO:0090543)
0.3 6.0 GO:0005922 connexon complex(GO:0005922)
0.3 3.3 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.3 5.4 GO:0097449 astrocyte projection(GO:0097449)
0.3 15.2 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.3 21.4 GO:0031526 brush border membrane(GO:0031526)
0.3 1.7 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.3 28.7 GO:0031225 anchored component of membrane(GO:0031225)
0.3 1.9 GO:0071203 WASH complex(GO:0071203)
0.3 7.9 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.3 4.9 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.3 3.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 6.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 15.5 GO:0031901 early endosome membrane(GO:0031901)
0.2 41.3 GO:0030424 axon(GO:0030424)
0.2 11.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 7.1 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 14.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 8.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 0.9 GO:0097470 ribbon synapse(GO:0097470)
0.2 25.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.2 15.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 24.7 GO:0043204 perikaryon(GO:0043204)
0.2 62.7 GO:0098793 presynapse(GO:0098793)
0.2 9.0 GO:0005871 kinesin complex(GO:0005871)
0.2 2.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.2 31.2 GO:0097223 sperm part(GO:0097223)
0.2 10.3 GO:0032587 ruffle membrane(GO:0032587)
0.2 9.3 GO:0005903 brush border(GO:0005903)
0.2 1.4 GO:0098642 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.2 23.2 GO:0005802 trans-Golgi network(GO:0005802)
0.2 18.6 GO:0030018 Z disc(GO:0030018)
0.2 7.0 GO:0030017 sarcomere(GO:0030017)
0.2 2.2 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 1.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 15.1 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 1.0 GO:0000815 ESCRT III complex(GO:0000815)
0.1 55.6 GO:0043025 neuronal cell body(GO:0043025)
0.1 2.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.2 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 7.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 2.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 32.1 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 3.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 3.3 GO:0045171 intercellular bridge(GO:0045171)
0.1 93.9 GO:0005739 mitochondrion(GO:0005739)
0.1 1.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 5.5 GO:0036064 ciliary basal body(GO:0036064)
0.1 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 2.5 GO:0030427 site of polarized growth(GO:0030427)
0.1 0.6 GO:0017119 Golgi transport complex(GO:0017119)
0.1 3.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 2.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 9.2 GO:0045202 synapse(GO:0045202)
0.1 6.7 GO:0005929 cilium(GO:0005929)
0.0 258.3 GO:0016021 integral component of membrane(GO:0016021)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
16.9 50.7 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
8.8 44.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
6.2 24.6 GO:0030294 receptor signaling protein tyrosine kinase inhibitor activity(GO:0030294)
5.4 37.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
4.7 14.1 GO:1990763 arrestin family protein binding(GO:1990763)
4.6 46.3 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
4.0 24.0 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
3.9 11.6 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
3.8 15.2 GO:0016842 amidine-lyase activity(GO:0016842)
3.7 11.2 GO:0045550 geranylgeranyl reductase activity(GO:0045550)
3.5 10.6 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
3.5 31.4 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
3.4 20.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
3.4 10.3 GO:0022852 glycine-gated chloride ion channel activity(GO:0022852)
3.0 18.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
3.0 8.9 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508)
2.8 8.3 GO:0031765 galanin receptor binding(GO:0031763) type 2 galanin receptor binding(GO:0031765) type 3 galanin receptor binding(GO:0031766)
2.7 18.9 GO:0045503 dynein light chain binding(GO:0045503)
2.6 18.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
2.5 7.6 GO:0017042 glycosylceramidase activity(GO:0017042)
2.5 7.4 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
2.3 11.7 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
2.3 11.6 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
2.3 11.3 GO:0001601 peptide YY receptor activity(GO:0001601)
2.2 8.9 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
2.2 6.6 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
2.1 6.4 GO:0017168 5-oxoprolinase (ATP-hydrolyzing) activity(GO:0017168)
2.1 10.7 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
2.1 10.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
2.0 6.0 GO:0019809 spermidine binding(GO:0019809)
2.0 7.9 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
2.0 7.9 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
1.9 36.7 GO:0017081 chloride channel regulator activity(GO:0017081)
1.9 13.4 GO:0048495 Roundabout binding(GO:0048495)
1.9 17.2 GO:0019992 diacylglycerol binding(GO:0019992)
1.8 5.4 GO:0047522 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
1.8 5.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
1.7 15.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
1.7 39.3 GO:0002162 dystroglycan binding(GO:0002162)
1.6 4.9 GO:0008948 oxaloacetate decarboxylase activity(GO:0008948)
1.6 13.0 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
1.6 9.7 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
1.6 6.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
1.6 45.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
1.5 14.7 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
1.5 39.6 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
1.4 11.5 GO:0003996 acyl-CoA ligase activity(GO:0003996)
1.4 11.2 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
1.4 5.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
1.3 14.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
1.3 5.0 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
1.3 5.0 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
1.2 15.8 GO:0098919 structural constituent of postsynaptic specialization(GO:0098879) structural constituent of postsynaptic density(GO:0098919)
1.2 17.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
1.2 15.5 GO:0045295 gamma-catenin binding(GO:0045295)
1.2 4.7 GO:0004743 pyruvate kinase activity(GO:0004743)
1.2 3.5 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
1.1 4.6 GO:0035877 death effector domain binding(GO:0035877)
1.1 4.6 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
1.1 4.5 GO:0003872 6-phosphofructokinase activity(GO:0003872)
1.1 9.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
1.1 21.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
1.1 8.7 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
1.1 5.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
1.1 10.8 GO:0051959 dynein light intermediate chain binding(GO:0051959)
1.1 6.4 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
1.0 28.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
1.0 10.5 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
1.0 42.6 GO:0005246 calcium channel regulator activity(GO:0005246)
1.0 4.1 GO:0004127 cytidylate kinase activity(GO:0004127)
1.0 36.9 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
1.0 8.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
1.0 10.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
1.0 15.7 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
1.0 61.7 GO:0051018 protein kinase A binding(GO:0051018)
1.0 3.9 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.9 2.8 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.9 7.1 GO:0016679 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.9 3.5 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.9 10.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.8 10.8 GO:0003796 lysozyme activity(GO:0003796)
0.8 2.5 GO:0004925 prolactin receptor activity(GO:0004925)
0.8 13.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.8 5.7 GO:0019808 polyamine binding(GO:0019808)
0.8 13.8 GO:0001594 trace-amine receptor activity(GO:0001594)
0.8 9.7 GO:0019864 IgG binding(GO:0019864)
0.8 3.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.8 2.4 GO:0099567 N-terminal myristoylation domain binding(GO:0031997) calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099567)
0.8 4.8 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.8 6.4 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.8 36.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.8 10.9 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.8 1.6 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.7 3.7 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.7 2.2 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.7 7.9 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.7 7.1 GO:0001846 opsonin binding(GO:0001846)
0.7 7.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.7 2.0 GO:0002061 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydrouracil dehydrogenase (NAD+) activity(GO:0004159) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.7 5.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.7 5.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.7 5.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.7 4.0 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.7 9.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.6 26.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.6 5.6 GO:0009881 photoreceptor activity(GO:0009881)
0.6 7.6 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.6 7.0 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.6 16.1 GO:0005158 insulin receptor binding(GO:0005158)
0.6 34.5 GO:0008146 sulfotransferase activity(GO:0008146)
0.6 7.5 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.6 15.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.6 11.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.5 6.5 GO:0004000 adenosine deaminase activity(GO:0004000)
0.5 3.8 GO:0031419 cobalamin binding(GO:0031419)
0.5 70.1 GO:0030165 PDZ domain binding(GO:0030165)
0.5 3.8 GO:0045545 syndecan binding(GO:0045545)
0.5 13.7 GO:0050699 WW domain binding(GO:0050699)
0.5 8.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.5 53.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.5 9.5 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.5 16.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.5 12.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.5 4.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.5 10.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.5 2.3 GO:0051373 FATZ binding(GO:0051373)
0.5 9.5 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.5 7.7 GO:0070410 co-SMAD binding(GO:0070410)
0.4 3.6 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.4 3.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.4 7.4 GO:0097602 cullin family protein binding(GO:0097602)
0.4 31.9 GO:0003777 microtubule motor activity(GO:0003777)
0.4 11.0 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.4 29.7 GO:0030276 clathrin binding(GO:0030276)
0.4 22.3 GO:0005080 protein kinase C binding(GO:0005080)
0.4 16.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.4 8.9 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.4 33.6 GO:0002039 p53 binding(GO:0002039)
0.4 1.5 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
0.4 7.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.4 1.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.4 3.8 GO:0010181 FMN binding(GO:0010181)
0.4 7.1 GO:0008199 ferric iron binding(GO:0008199)
0.4 5.2 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.4 37.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.4 58.3 GO:0008017 microtubule binding(GO:0008017)
0.4 9.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.3 10.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.3 19.1 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.3 2.9 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.3 4.9 GO:0001056 RNA polymerase III activity(GO:0001056)
0.3 4.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.3 1.2 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.3 9.5 GO:0099589 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.3 1.7 GO:0005047 signal recognition particle binding(GO:0005047)
0.3 109.6 GO:0005549 odorant binding(GO:0005549)
0.3 5.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.3 2.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.3 5.6 GO:0004623 phospholipase A2 activity(GO:0004623)
0.2 1.7 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273) potassium ion antiporter activity(GO:0022821)
0.2 6.4 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2 3.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.2 16.6 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.2 1.1 GO:0001729 ceramide kinase activity(GO:0001729)
0.2 0.6 GO:0030283 testosterone dehydrogenase [NAD(P)] activity(GO:0030283)
0.2 4.2 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.2 22.0 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.2 2.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 4.7 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 1.9 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 2.7 GO:0016289 CoA hydrolase activity(GO:0016289)
0.2 2.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 4.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 2.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 2.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 5.3 GO:0005109 frizzled binding(GO:0005109)
0.1 126.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 4.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 30.7 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 4.5 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 14.0 GO:0005516 calmodulin binding(GO:0005516)
0.1 7.9 GO:0019003 GDP binding(GO:0019003)
0.1 28.5 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 2.4 GO:0005112 Notch binding(GO:0005112)
0.1 7.9 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.1 12.7 GO:0005179 hormone activity(GO:0005179)
0.1 5.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 0.6 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 12.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 4.4 GO:0004177 aminopeptidase activity(GO:0004177)
0.1 9.8 GO:0008565 protein transporter activity(GO:0008565)
0.1 6.9 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.1 0.7 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 4.7 GO:0017022 myosin binding(GO:0017022)
0.1 5.2 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 0.5 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 1.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 9.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 2.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 7.8 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.1 0.3 GO:0003921 GMP synthase activity(GO:0003921) GMP synthase (glutamine-hydrolyzing) activity(GO:0003922)
0.1 6.7 GO:0005178 integrin binding(GO:0005178)
0.1 6.1 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.1 2.0 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 2.3 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.8 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 6.5 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 3.5 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.5 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 47.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.7 26.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.6 33.3 PID BMP PATHWAY BMP receptor signaling
0.6 3.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.5 6.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.5 20.1 ST G ALPHA I PATHWAY G alpha i Pathway
0.4 4.9 ST STAT3 PATHWAY STAT3 Pathway
0.4 23.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.4 25.1 PID LKB1 PATHWAY LKB1 signaling events
0.4 9.0 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.4 11.5 PID FAS PATHWAY FAS (CD95) signaling pathway
0.4 9.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.3 13.0 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.3 8.0 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.3 11.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.2 9.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 4.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 4.1 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 10.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 2.5 PID FOXO PATHWAY FoxO family signaling
0.1 1.7 PID IL3 PATHWAY IL3-mediated signaling events
0.1 2.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 2.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 1.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 3.2 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 1.7 PID FGF PATHWAY FGF signaling pathway
0.0 0.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.5 ST JNK MAPK PATHWAY JNK MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 36.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
2.6 92.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
2.5 7.5 REACTOME XENOBIOTICS Genes involved in Xenobiotics
1.3 20.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
1.2 26.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
1.0 40.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
1.0 20.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
1.0 17.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.9 11.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.9 13.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.8 4.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.8 19.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.8 14.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.7 11.0 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.7 22.4 REACTOME KINESINS Genes involved in Kinesins
0.7 5.6 REACTOME OPSINS Genes involved in Opsins
0.7 33.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.7 42.0 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.7 14.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.7 34.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.6 10.0 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.5 7.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.5 10.5 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.5 7.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.5 13.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.5 9.0 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.5 6.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.4 9.0 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.4 5.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.4 15.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.4 6.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.4 10.3 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.4 9.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.4 6.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.4 5.6 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.3 11.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.3 7.1 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.3 8.7 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.3 6.0 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.3 8.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.3 8.5 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.3 4.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.3 2.5 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.3 4.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.3 7.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.3 4.0 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.3 2.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.3 1.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 4.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.2 13.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.2 25.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 3.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 11.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.2 3.8 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 5.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.2 2.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 10.8 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.2 7.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 5.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.2 0.8 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.2 4.1 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.2 2.0 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 2.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 13.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 3.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 4.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 5.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 7.8 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.1 1.6 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 1.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 0.4 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.1 0.7 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 3.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.1 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 5.7 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.2 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 4.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.6 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 1.1 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR