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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Hoxa13

Z-value: 0.96

Motif logo

Transcription factors associated with Hoxa13

Gene Symbol Gene ID Gene Info
ENSRNOG00000057061 homeo box A13

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxa13rn6_v1_chr4_-_82229397_822293970.164.7e-03Click!

Activity profile of Hoxa13 motif

Sorted Z-values of Hoxa13 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_5773036 33.34 ENSRNOT00000041365
FRY microtubule binding protein
chr2_+_223029559 32.70 ENSRNOT00000045584

chr12_-_2438817 30.78 ENSRNOT00000037059
C-C motif chemokine ligand 25
chr1_+_12915734 27.55 ENSRNOT00000089066
taxilin beta
chr1_-_16687817 26.82 ENSRNOT00000091376
ENSRNOT00000081620
MYB proto-oncogene, transcription factor
chr17_-_43626538 26.12 ENSRNOT00000074292
histone cluster 2, H3c2
chr3_-_60166013 25.78 ENSRNOT00000024922
WAS/WASL interacting protein family, member 1
chr14_-_71814523 25.61 ENSRNOT00000004094
bone marrow stromal cell antigen 1
chr4_-_163445302 24.03 ENSRNOT00000087106
killer cell lectin-like receptor subfamily C, member 3
chr4_+_78371121 23.46 ENSRNOT00000059157
GTPase, IMAP family member 1
chr7_+_38742051 22.93 ENSRNOT00000006070
decorin
chr2_+_93792601 22.31 ENSRNOT00000014701
ENSRNOT00000077311
fatty acid binding protein 4
chr17_+_47870611 21.79 ENSRNOT00000078555

chr1_+_8310577 20.67 ENSRNOT00000015131
human immunodeficiency virus type I enhancer binding protein 2
chr1_+_219403970 20.05 ENSRNOT00000029607
protein tyrosine phosphatase, receptor type, C-associated protein
chrX_-_77675487 19.48 ENSRNOT00000042799
cysteinyl leukotriene receptor 1
chrX_-_10031167 19.07 ENSRNOT00000060988
G protein-coupled receptor 34
chr11_-_45124423 18.43 ENSRNOT00000046383
filamin A interacting protein 1-like
chr4_+_70572942 18.38 ENSRNOT00000051964

chr5_+_90338795 17.26 ENSRNOT00000077864
ENSRNOT00000058882
similar to RIKEN cDNA 2310003M01
chr2_+_183674522 17.11 ENSRNOT00000014433
transmembrane protein 154
chr4_+_44597123 17.01 ENSRNOT00000078250
caveolin 1
chr2_-_88553086 16.99 ENSRNOT00000042494
similar to solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr12_-_40590361 16.87 ENSRNOT00000067503
transmembrane protein 116
chr4_-_109532234 16.54 ENSRNOT00000008665
regenerating family member 3 gamma
chr4_-_170860225 16.35 ENSRNOT00000007577
matrix Gla protein
chr16_+_2537248 16.32 ENSRNOT00000017995
ankyrin repeat and SOCS box-containing 14
chr15_+_33606124 16.21 ENSRNOT00000065210

chr1_-_141471010 16.00 ENSRNOT00000082164
perilipin 1
chr9_-_52238564 15.95 ENSRNOT00000005073
collagen type V alpha 2 chain
chr13_-_61070599 15.79 ENSRNOT00000005251
regulator of G-protein signaling 1
chr18_+_17091310 15.59 ENSRNOT00000093285
formin homology 2 domain containing 3
chr2_-_208215187 15.50 ENSRNOT00000047836
RAP1A, member of RAS oncogene family
chr4_+_14151343 14.38 ENSRNOT00000061687
ENSRNOT00000076573
ENSRNOT00000077219
ENSRNOT00000008319
CD36 molecule
chr10_+_57251253 14.36 ENSRNOT00000043171
60S ribosomal protein L36a
chr2_-_257484587 14.10 ENSRNOT00000083344
nexilin (F actin binding protein)
chr3_+_17107861 13.10 ENSRNOT00000043097

chr11_+_86421106 12.99 ENSRNOT00000002599
serine/threonine-protein phosphatase 2A catalytic subunit alpha-like
chr7_-_107391184 12.96 ENSRNOT00000056793
transmembrane protein 71
chr13_-_78521911 12.84 ENSRNOT00000087506
RAB GTPase activating protein 1-like
chr8_-_109560747 12.56 ENSRNOT00000087334
protein phosphatase 2, regulatory subunit B'', alpha
chr10_-_31493419 12.41 ENSRNOT00000009211
IL2-inducible T-cell kinase
chr7_-_14418950 12.40 ENSRNOT00000066722
RAS protein activator like 3
chr19_-_6293 12.39 ENSRNOT00000074240
similar to carboxylesterase 2 (intestine, liver)
chr6_+_132551394 12.26 ENSRNOT00000019583
Enah/Vasp-like
chr20_-_18060661 12.24 ENSRNOT00000070925

chr9_-_81400987 12.07 ENSRNOT00000035277
tensin 1
chr4_-_163445136 12.03 ENSRNOT00000080299
killer cell lectin-like receptor subfamily C, member 3
chr2_-_117666683 11.85 ENSRNOT00000015479

chr11_+_85508300 11.84 ENSRNOT00000038646

chr17_+_32973695 11.78 ENSRNOT00000065674
similar to OTTMUSP00000000621
chr4_+_155313671 11.71 ENSRNOT00000020812
microfibrillar associated protein 5
chr10_-_56558487 11.69 ENSRNOT00000023256
solute carrier family 2 member 4
chr17_-_18590536 11.56 ENSRNOT00000078992
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr2_+_248178389 11.23 ENSRNOT00000037339
guanylate binding protein 5
chr7_+_44146237 10.95 ENSRNOT00000058842
Ras association domain family member 9
chr4_+_162493908 10.92 ENSRNOT00000072064
C-type lectin domain family 2, member D
chrX_+_51286737 10.86 ENSRNOT00000035692
dystrophin
chr13_-_92089980 10.70 ENSRNOT00000036040
myeloid cell nuclear differentiation antigen
chr17_-_84247038 10.70 ENSRNOT00000068553
nebulette
chr4_-_51199570 10.68 ENSRNOT00000010788
solute carrier family 13 member 1
chr14_-_72122158 10.67 ENSRNOT00000064495
C1q and tumor necrosis factor related protein 7
chr1_-_204087001 10.65 ENSRNOT00000051853
carboxypeptidase X (M14 family), member 2
chr14_+_83510640 10.56 ENSRNOT00000089928
ENSRNOT00000082242
ENSRNOT00000025378
POZ (BTB) and AT hook containing zinc finger 1
chr9_-_9702306 10.46 ENSRNOT00000082341
thyroid hormone receptor interactor 10
chr17_-_65955606 10.40 ENSRNOT00000067949
ENSRNOT00000023601
ryanodine receptor 2
chr12_-_13668515 10.34 ENSRNOT00000086847
fascin actin-bundling protein 1
chr13_-_51297621 10.23 ENSRNOT00000030926
NADH:ubiquinone oxidoreductase subunit V3
chr1_-_25839198 10.23 ENSRNOT00000090388
ENSRNOT00000092757
ENSRNOT00000042072
triadin
chr10_+_764421 10.21 ENSRNOT00000084608
ENSRNOT00000087567
myosin heavy chain 11
chr4_+_157726941 10.20 ENSRNOT00000025081
vesicle-associated membrane protein 1
chr5_-_16799776 10.16 ENSRNOT00000011721
PLAG1 zinc finger
chr14_-_62595854 10.09 ENSRNOT00000003024
Yip1 domain family, member 7
chr4_-_180234804 10.08 ENSRNOT00000070957
basic helix-loop-helix family, member e41
chrM_+_3904 10.07 ENSRNOT00000040993
mitochondrially encoded NADH dehydrogenase 2
chr20_+_4363152 9.91 ENSRNOT00000000508
ENSRNOT00000084841
ENSRNOT00000072848
ENSRNOT00000077561
advanced glycosylation end product-specific receptor
chr4_+_64088900 9.91 ENSRNOT00000075341
cholinergic receptor, muscarinic 2
chr17_+_43616247 9.75 ENSRNOT00000072019
histone cluster 1, H3a
chr7_+_34533543 9.75 ENSRNOT00000007412
ENSRNOT00000084185
netrin 4
chr11_+_80255790 9.65 ENSRNOT00000002522
B-cell CLL/lymphoma 6
chr16_-_88347369 9.63 ENSRNOT00000019797
pyruvate dehydrogenase (lipoamide) alpha 1-like 1
chr2_+_148262110 9.58 ENSRNOT00000046641

chr15_-_34693034 9.58 ENSRNOT00000083314
mast cell protease 8
chr4_-_163214678 9.49 ENSRNOT00000091602
C-type lectin domain family 1, member A
chr3_-_21061070 9.42 ENSRNOT00000044461
olfactory receptor 422
chr3_+_72385666 9.18 ENSRNOT00000011168
proteoglycan 2
chr15_+_30570483 9.17 ENSRNOT00000071740

chr11_-_46369577 9.17 ENSRNOT00000049859
ENSRNOT00000047817
ENSRNOT00000002220
ENSRNOT00000002223
ENSRNOT00000063864
ENSRNOT00000070871
ENSRNOT00000072140
ABI family member 3 binding protein
chr10_+_72272248 9.08 ENSRNOT00000003908
carbonic anhydrase 4
chr2_-_45518502 9.07 ENSRNOT00000014627
heat shock protein family B (small) member 3
chr10_-_107386072 9.05 ENSRNOT00000004290
TIMP metallopeptidase inhibitor 2
chr4_-_163402561 8.95 ENSRNOT00000091890
killer cell lectin like receptor K1
chr9_-_88534710 8.95 ENSRNOT00000020880
transmembrane 4 L six family member 20
chr9_+_52023295 8.76 ENSRNOT00000004956
collagen type III alpha 1 chain
chr5_-_174921 8.75 ENSRNOT00000056239
TIMELESS interacting protein like 1
chr15_-_95514259 8.68 ENSRNOT00000038433
SLIT and NTRK-like family, member 6
chr5_-_146795866 8.60 ENSRNOT00000065640
toll-like receptor 12
chr3_+_53563194 8.54 ENSRNOT00000048300
xin actin-binding repeat containing 2
chr2_+_236625357 8.53 ENSRNOT00000081248
3'-phosphoadenosine 5'-phosphosulfate synthase 1
chr14_+_83510278 8.51 ENSRNOT00000081161
POZ (BTB) and AT hook containing zinc finger 1
chr10_-_70337532 8.49 ENSRNOT00000055963
schlafen family member 13
chr4_+_14070553 8.46 ENSRNOT00000077505
CD36 molecule
chr17_+_47241017 8.42 ENSRNOT00000092193
G protein-coupled receptor 141
chr2_-_205212681 8.38 ENSRNOT00000022575
thyroid stimulating hormone, beta
chr2_-_170301348 8.36 ENSRNOT00000088131
sucrase-isomaltase
chr13_-_26769374 8.25 ENSRNOT00000003768
BCL2, apoptosis regulator
chr2_+_40554146 8.23 ENSRNOT00000015138
phosphodiesterase 4D
chr16_-_10941414 8.19 ENSRNOT00000086627
ENSRNOT00000085414
ENSRNOT00000081631
ENSRNOT00000087521
ENSRNOT00000083623
LIM domain binding 3
chr2_+_45182402 8.06 ENSRNOT00000060673
similar to BC067074 protein
chr13_+_57243877 7.94 ENSRNOT00000083693
potassium sodium-activated channel subfamily T member 2
chr15_+_31417147 7.93 ENSRNOT00000092182

chr2_+_198359754 7.89 ENSRNOT00000048582
histone cluster 2 H2A family member b
chr18_+_15738809 7.86 ENSRNOT00000075444
microtubule-associated protein, RP/EB family, member 2
chr5_+_118418799 7.86 ENSRNOT00000012052
ALG6, alpha-1,3-glucosyltransferase
chr7_-_143228060 7.82 ENSRNOT00000088923
ENSRNOT00000012640
keratin 75
chr3_+_149624712 7.78 ENSRNOT00000018581
BPI fold containing family A, member 1
chr4_-_170740274 7.75 ENSRNOT00000012212
guanylate cyclase 2C
chr2_-_187909394 7.71 ENSRNOT00000032355
RAB25, member RAS oncogene family
chr5_-_150167077 7.67 ENSRNOT00000088493
ENSRNOT00000013761
ENSRNOT00000067349
ENSRNOT00000051097
ENSRNOT00000067189
erythrocyte membrane protein band 4.1
chr15_-_48284548 7.66 ENSRNOT00000038336
homeobox containing 1
chr1_-_62558033 7.64 ENSRNOT00000015520
zinc finger protein 40
chr1_+_75428027 7.60 ENSRNOT00000058334
phospholipase A2, group IVC
chr5_-_60191941 7.58 ENSRNOT00000033373
paired box 5
chr4_-_82209933 7.52 ENSRNOT00000091106
homeobox protein Hox-A10-like
chr2_+_38230757 7.51 ENSRNOT00000048598
similar to 60S ribosomal protein L23a
chrX_+_28539158 7.31 ENSRNOT00000073535
toll-like receptor 8
chr14_-_34561696 7.28 ENSRNOT00000059763
steroid 5 alpha-reductase 3
chr16_-_74700815 7.27 ENSRNOT00000081297
thrombospondin type 1 domain containing 1
chr11_+_85532526 7.24 ENSRNOT00000036565

chr17_-_44758170 7.20 ENSRNOT00000091176
histone cluster 1 H2B family member o
chr8_-_133128290 7.17 ENSRNOT00000008783
chemokine (C-C motif) receptor 1-like 1
chr1_-_69835185 7.11 ENSRNOT00000020757
spindle assembly abnormal protein 6 homolog
chr16_-_14360555 7.09 ENSRNOT00000065460
hypothetical gene supported by AF152002
chrX_+_78042859 7.00 ENSRNOT00000003286
lysophosphatidic acid receptor 4
chr20_+_3364814 6.97 ENSRNOT00000001077
hypothetical protein MGC:15854
chr6_-_141321108 6.94 ENSRNOT00000040556

chr4_-_82295470 6.93 ENSRNOT00000091073
homeobox A10
chr15_-_49773178 6.91 ENSRNOT00000090328

chr2_-_210116038 6.90 ENSRNOT00000074950
similar to NADH-ubiquinone oxidoreductase B9 subunit (Complex I-B9) (CI-B9)
chr10_-_15211325 6.84 ENSRNOT00000027083
ras homolog family member T2
chr7_-_73130740 6.84 ENSRNOT00000075584
RIKEN cDNA 9430069I07 gene
chr2_-_31753528 6.79 ENSRNOT00000075057
phosphoinositide-3-kinase regulatory subunit 1
chr10_+_54155876 6.76 ENSRNOT00000072855
growth arrest specific 7
chr2_-_86475096 6.75 ENSRNOT00000075247
ENSRNOT00000075062
zinc finger protein 43-like
chr6_-_142585188 6.75 ENSRNOT00000067437

chr4_-_173640684 6.74 ENSRNOT00000010728
RERG like
chrX_+_77119911 6.71 ENSRNOT00000080141
ATPase copper transporting alpha
chrM_-_14061 6.71 ENSRNOT00000051268
mitochondrially encoded NADH dehydrogenase 6
chr8_+_117906014 6.70 ENSRNOT00000056180
serine peptidase inhibitor, Kazal type 8
chr8_+_118066988 6.69 ENSRNOT00000056161
microtubule-associated protein 4
chr1_+_199352344 6.58 ENSRNOT00000026466
branched chain ketoacid dehydrogenase kinase
chrX_-_139916883 6.55 ENSRNOT00000090442
glypican 3
chr5_-_50068706 6.54 ENSRNOT00000084643
origin recognition complex, subunit 3
chr9_-_69878706 6.51 ENSRNOT00000035879
INO80 complex subunit D
chr9_+_20048121 6.50 ENSRNOT00000014791
meprin 1 subunit alpha
chr3_+_110855000 6.47 ENSRNOT00000081613
kinetochore scaffold 1
chr1_+_199351628 6.43 ENSRNOT00000078578
branched chain ketoacid dehydrogenase kinase
chr1_-_129217058 6.42 ENSRNOT00000086439
pyroglutamyl-peptidase I-like
chr10_-_37311625 6.42 ENSRNOT00000043343
jade family PHD finger 2
chrX_+_156429585 6.41 ENSRNOT00000083203
ENSRNOT00000077322
deoxyribonuclease 1-like 1
chr1_-_124803363 6.41 ENSRNOT00000066380
Kruppel-like factor 13
chr2_-_45077219 6.41 ENSRNOT00000014319
granzyme K
chr2_+_113984646 6.37 ENSRNOT00000016799
TRAF2 and NCK interacting kinase
chr2_-_96509424 6.32 ENSRNOT00000090866
zinc finger, C2HC-type containing 1A
chr15_+_31456265 6.29 ENSRNOT00000075092

chr16_+_85331866 6.28 ENSRNOT00000019615
DNA ligase 4
chr8_-_49158971 6.26 ENSRNOT00000020573
lysine methyltransferase 2A
chr3_+_161236898 6.24 ENSRNOT00000082303
ENSRNOT00000020323
ubiquitin-conjugating enzyme E2C
chr1_+_42121636 6.23 ENSRNOT00000025616
myc target 1
chr2_-_231648122 6.22 ENSRNOT00000014962
ankyrin 2
chr3_-_7796385 6.20 ENSRNOT00000082489
netrin G2
chr16_+_31734944 6.19 ENSRNOT00000059673
palladin, cytoskeletal associated protein
chr14_-_45165207 6.19 ENSRNOT00000002960
Kruppel like factor 3
chr6_+_55812747 6.18 ENSRNOT00000008106
sclerostin domain containing 1
chr1_+_137860946 6.17 ENSRNOT00000031334
ATP/GTP binding protein-like 1
chr3_+_17889972 6.17 ENSRNOT00000073021

chr17_-_389967 6.12 ENSRNOT00000023865
fructose-bisphosphatase 2
chr15_+_31097291 6.11 ENSRNOT00000075456

chr12_-_38916237 6.03 ENSRNOT00000074517
transmembrane protein 120B
chr8_+_82037977 6.02 ENSRNOT00000082288
myosin VA
chr6_-_86914883 6.01 ENSRNOT00000091202
MIS18 binding protein 1
chr15_+_32324830 5.93 ENSRNOT00000071598

chr3_+_44025300 5.90 ENSRNOT00000006319
polypeptide N-acetylgalactosaminyltransferase 5
chr1_+_174862698 5.89 ENSRNOT00000013276
SWAP switching B-cell complex 70
chr3_+_151126591 5.88 ENSRNOT00000025859
myosin heavy chain 7B
chr7_-_18793289 5.88 ENSRNOT00000036375

chr3_+_100373439 5.83 ENSRNOT00000085176
kinesin family member 18A
chr1_-_169534896 5.78 ENSRNOT00000082645
tripartite motif-containing 30C
chr2_+_113984824 5.77 ENSRNOT00000086399
TRAF2 and NCK interacting kinase
chr9_+_82741920 5.72 ENSRNOT00000027337
solute carrier family 4 member 3
chr6_-_54020406 5.72 ENSRNOT00000086038
histone deacetylase 9
chr1_-_60407295 5.71 ENSRNOT00000078350
vomeronasal 1 receptor 12
chr18_-_74478341 5.69 ENSRNOT00000074572
solute carrier family 14 member 1
chr3_-_16750564 5.66 ENSRNOT00000084111

chrX_-_157200981 5.66 ENSRNOT00000087364

chr12_-_51877624 5.66 ENSRNOT00000056800
checkpoint kinase 2
chr9_-_45206427 5.66 ENSRNOT00000042227
AF4/FMR2 family, member 3
chr12_-_22472044 5.65 ENSRNOT00000073356
UFM1-specific peptidase 1
chr3_-_24601063 5.64 ENSRNOT00000037043
40S ribosomal protein S17-like
chr1_-_89483988 5.62 ENSRNOT00000028603
FXYD domain-containing ion transport regulator 7

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxa13

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
8.9 26.8 GO:2000845 positive regulation of testosterone secretion(GO:2000845)
8.3 33.3 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
6.2 30.8 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
5.9 35.3 GO:0061737 leukotriene signaling pathway(GO:0061737)
5.7 17.0 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) regulation of inward rectifier potassium channel activity(GO:1901979) positive regulation of gap junction assembly(GO:1903598) receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
4.2 12.6 GO:0090249 cell motility involved in somitogenic axis elongation(GO:0090247) regulation of cell motility involved in somitogenic axis elongation(GO:0090249)
4.0 15.9 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
3.8 22.8 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
3.6 10.9 GO:0021629 muscle attachment(GO:0016203) olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
3.6 10.7 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
3.5 10.4 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
3.3 9.9 GO:1905204 response to selenite ion(GO:0072714) negative regulation of connective tissue replacement(GO:1905204)
3.3 6.5 GO:0072138 mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
3.2 9.7 GO:0043380 regulation of memory T cell differentiation(GO:0043380)
3.1 9.4 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
3.1 15.5 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
3.1 9.2 GO:0002215 defense response to nematode(GO:0002215)
3.0 8.9 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223) negative regulation of natural killer cell chemotaxis(GO:2000502)
2.9 22.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
2.8 11.0 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
2.8 8.3 GO:0006808 regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740) negative regulation of retinal cell programmed cell death(GO:0046671)
2.7 8.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
2.6 5.1 GO:0060559 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
2.4 7.3 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
2.4 9.7 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
2.3 13.7 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
2.2 8.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
2.2 6.5 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
2.1 6.3 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
2.1 6.2 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
2.0 24.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
2.0 9.9 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
2.0 5.9 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
1.9 5.6 GO:0033128 negative regulation of histone phosphorylation(GO:0033128)
1.8 5.4 GO:0032912 negative regulation of transforming growth factor beta2 production(GO:0032912)
1.8 5.3 GO:0097213 protein targeting to lysosome involved in chaperone-mediated autophagy(GO:0061740) regulation of lysosomal membrane permeability(GO:0097213) positive regulation of lysosomal membrane permeability(GO:0097214)
1.7 6.7 GO:0051542 elastin biosynthetic process(GO:0051542) regulation of cytochrome-c oxidase activity(GO:1904959)
1.6 4.9 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
1.6 7.9 GO:0060005 vestibular reflex(GO:0060005)
1.6 6.3 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
1.6 18.8 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
1.6 4.7 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
1.6 6.2 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
1.6 7.8 GO:0050828 regulation of liquid surface tension(GO:0050828)
1.6 6.2 GO:0098907 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
1.5 6.1 GO:0046351 disaccharide biosynthetic process(GO:0046351)
1.5 6.0 GO:0051643 endoplasmic reticulum localization(GO:0051643)
1.5 4.5 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
1.5 4.5 GO:0046340 diacylglycerol catabolic process(GO:0046340)
1.5 8.7 GO:0048478 replication fork protection(GO:0048478)
1.5 7.3 GO:0016095 polyprenol catabolic process(GO:0016095)
1.4 4.3 GO:0061470 T follicular helper cell differentiation(GO:0061470)
1.4 27.4 GO:0050872 white fat cell differentiation(GO:0050872)
1.4 5.7 GO:1903463 regulation of mitotic cell cycle DNA replication(GO:1903463)
1.4 4.2 GO:0018343 protein farnesylation(GO:0018343)
1.4 4.1 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
1.4 5.4 GO:0070560 protein secretion by platelet(GO:0070560)
1.3 9.1 GO:1905049 negative regulation of metallopeptidase activity(GO:1905049)
1.3 27.6 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
1.2 12.4 GO:0001865 NK T cell differentiation(GO:0001865)
1.2 7.4 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
1.2 8.3 GO:0000103 sulfate assimilation(GO:0000103)
1.2 3.5 GO:0060383 positive regulation of DNA strand elongation(GO:0060383)
1.2 4.7 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
1.2 3.5 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
1.1 30.9 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
1.1 3.4 GO:0072720 response to dithiothreitol(GO:0072720)
1.1 1.1 GO:0002780 antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780)
1.1 4.3 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
1.1 3.2 GO:0006407 rRNA export from nucleus(GO:0006407)
1.1 12.8 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
1.0 15.6 GO:0051639 actin filament network formation(GO:0051639)
1.0 6.2 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
1.0 3.0 GO:2000660 negative regulation of chemokine biosynthetic process(GO:0045079) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
1.0 10.1 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
1.0 6.0 GO:1900157 regulation of bone mineralization involved in bone maturation(GO:1900157)
1.0 3.9 GO:0060178 regulation of exocyst localization(GO:0060178)
0.9 10.3 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.9 5.6 GO:0071918 urea transmembrane transport(GO:0071918)
0.9 5.6 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.9 13.0 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.9 3.6 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.9 2.7 GO:0010643 positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
0.9 2.7 GO:0071461 cellular response to redox state(GO:0071461)
0.9 12.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.8 3.3 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.8 5.7 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.8 2.4 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186) negative regulation of synaptic vesicle recycling(GO:1903422)
0.8 14.4 GO:0009750 response to fructose(GO:0009750)
0.8 3.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.8 11.7 GO:0097435 fibril organization(GO:0097435)
0.8 3.8 GO:0006177 GMP biosynthetic process(GO:0006177)
0.8 2.3 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.8 3.8 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016) interleukin-2-mediated signaling pathway(GO:0038110)
0.8 5.3 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.8 3.8 GO:0061709 reticulophagy(GO:0061709)
0.7 3.7 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.7 3.6 GO:0042256 mature ribosome assembly(GO:0042256)
0.7 7.9 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.7 6.4 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.7 5.6 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.7 7.7 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.7 4.9 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.7 4.7 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.7 4.7 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808) presynaptic dense core granule exocytosis(GO:0099525)
0.7 25.6 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.6 3.2 GO:0021873 forebrain neuroblast division(GO:0021873)
0.6 3.2 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.6 9.5 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.6 2.5 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.6 3.1 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.6 3.7 GO:0072014 proximal tubule development(GO:0072014)
0.6 3.7 GO:1990928 response to amino acid starvation(GO:1990928)
0.6 3.0 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.6 3.0 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.6 5.3 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.6 1.7 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.6 3.5 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.6 2.9 GO:0045605 negative regulation of epidermal cell differentiation(GO:0045605)
0.6 4.6 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.6 2.3 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.6 5.5 GO:0006657 CDP-choline pathway(GO:0006657)
0.6 10.5 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.5 1.6 GO:1902172 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.5 2.7 GO:0089700 protein kinase D signaling(GO:0089700)
0.5 7.6 GO:0021670 lateral ventricle development(GO:0021670)
0.5 5.4 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
0.5 0.5 GO:1902623 negative regulation of neutrophil migration(GO:1902623)
0.5 4.8 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.5 3.1 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.5 3.6 GO:0001927 exocyst assembly(GO:0001927)
0.5 10.7 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.5 7.5 GO:0034501 protein localization to kinetochore(GO:0034501)
0.5 11.7 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.5 10.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.5 10.2 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.5 1.5 GO:0061341 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.5 6.2 GO:0003334 keratinocyte development(GO:0003334)
0.5 3.8 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.5 1.9 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.5 6.4 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.5 4.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.5 10.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.5 4.1 GO:1904044 response to aldosterone(GO:1904044)
0.5 8.1 GO:0007567 parturition(GO:0007567)
0.4 1.3 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.4 3.6 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.4 6.9 GO:0002227 innate immune response in mucosa(GO:0002227)
0.4 7.7 GO:0031268 pseudopodium organization(GO:0031268)
0.4 17.0 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.4 2.5 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.4 6.7 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.4 1.2 GO:0006106 fumarate metabolic process(GO:0006106)
0.4 1.2 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.4 8.6 GO:0042832 defense response to protozoan(GO:0042832)
0.4 2.5 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.4 2.8 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.4 2.0 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.4 7.5 GO:0070166 enamel mineralization(GO:0070166)
0.4 1.9 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.4 2.5 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.3 1.4 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.3 1.7 GO:0034334 adherens junction maintenance(GO:0034334)
0.3 2.3 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.3 5.9 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.3 8.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.3 2.3 GO:0043615 astrocyte cell migration(GO:0043615)
0.3 2.9 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.3 1.3 GO:0000707 meiotic DNA recombinase assembly(GO:0000707) strand invasion(GO:0042148)
0.3 1.6 GO:0070294 renal sodium ion absorption(GO:0070294)
0.3 5.7 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.3 5.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.3 3.4 GO:0042118 endothelial cell activation(GO:0042118)
0.3 1.5 GO:0060014 granulosa cell differentiation(GO:0060014)
0.3 1.5 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.3 16.7 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.3 1.5 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.3 2.7 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.3 5.0 GO:0035641 locomotory exploration behavior(GO:0035641)
0.3 3.5 GO:1901409 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.3 1.1 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
0.3 7.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.3 0.8 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.3 10.2 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.3 1.6 GO:0071051 U4 snRNA 3'-end processing(GO:0034475) DNA deamination(GO:0045006) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.3 4.0 GO:0090161 Golgi ribbon formation(GO:0090161)
0.3 7.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.3 2.4 GO:0050957 equilibrioception(GO:0050957)
0.3 1.6 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.3 7.0 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.3 10.3 GO:0045214 sarcomere organization(GO:0045214)
0.3 3.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.3 16.3 GO:0030500 regulation of bone mineralization(GO:0030500)
0.3 5.8 GO:0072520 seminiferous tubule development(GO:0072520)
0.3 15.4 GO:1902807 negative regulation of cell cycle G1/S phase transition(GO:1902807)
0.3 1.5 GO:0060732 regulation of inositol phosphate biosynthetic process(GO:0010919) positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.2 2.9 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.2 4.9 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.2 1.9 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.2 1.0 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.2 3.8 GO:0036297 interstrand cross-link repair(GO:0036297)
0.2 5.5 GO:0002675 positive regulation of acute inflammatory response(GO:0002675)
0.2 0.7 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.2 4.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 3.7 GO:0061436 establishment of skin barrier(GO:0061436)
0.2 6.8 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.2 7.9 GO:0010761 fibroblast migration(GO:0010761)
0.2 1.8 GO:0006968 cellular defense response(GO:0006968)
0.2 1.8 GO:0016075 rRNA catabolic process(GO:0016075)
0.2 2.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.2 5.5 GO:0030488 tRNA methylation(GO:0030488)
0.2 7.1 GO:0090630 activation of GTPase activity(GO:0090630)
0.2 1.7 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.2 0.8 GO:0002188 translation reinitiation(GO:0002188)
0.2 24.9 GO:0031032 actomyosin structure organization(GO:0031032)
0.2 8.5 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.2 3.7 GO:1902572 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.2 1.4 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.2 2.2 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.2 0.8 GO:0014042 positive regulation of neuron maturation(GO:0014042)
0.2 3.6 GO:0042119 neutrophil activation(GO:0042119)
0.2 2.5 GO:0035357 peroxisome proliferator activated receptor signaling pathway(GO:0035357)
0.2 0.6 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.2 2.0 GO:0042048 olfactory behavior(GO:0042048)
0.2 0.5 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.2 1.5 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 7.8 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.2 1.9 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.2 0.5 GO:1904683 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) regulation of metalloendopeptidase activity(GO:1904683) positive regulation of metalloendopeptidase activity(GO:1904685)
0.2 16.3 GO:0030183 B cell differentiation(GO:0030183)
0.2 6.0 GO:0007099 centriole replication(GO:0007099)
0.2 1.7 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.2 5.3 GO:0018345 protein palmitoylation(GO:0018345)
0.2 4.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.2 0.6 GO:0034240 negative regulation of macrophage fusion(GO:0034240)
0.2 2.7 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.2 2.7 GO:0030252 growth hormone secretion(GO:0030252)
0.1 1.0 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 0.3 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.1 0.4 GO:1903925 response to bisphenol A(GO:1903925)
0.1 0.4 GO:1900095 random inactivation of X chromosome(GO:0060816) regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1 1.0 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 2.1 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.1 8.0 GO:0045761 regulation of adenylate cyclase activity(GO:0045761)
0.1 0.8 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 1.1 GO:0060736 prostate gland growth(GO:0060736)
0.1 1.3 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.1 1.4 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 5.1 GO:0006284 base-excision repair(GO:0006284)
0.1 2.5 GO:0060065 uterus development(GO:0060065)
0.1 0.7 GO:0048820 hair follicle maturation(GO:0048820)
0.1 2.9 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.1 1.9 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.1 1.5 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 2.5 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.1 1.6 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 0.5 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.1 5.6 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 2.9 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 3.1 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.1 1.8 GO:1905145 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 2.7 GO:0042220 response to cocaine(GO:0042220)
0.1 2.5 GO:0010842 retina layer formation(GO:0010842)
0.1 3.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 0.3 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.1 0.9 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 5.1 GO:0006334 nucleosome assembly(GO:0006334)
0.1 3.4 GO:0051310 metaphase plate congression(GO:0051310)
0.1 3.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 2.2 GO:0006379 mRNA cleavage(GO:0006379)
0.1 4.7 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.1 1.1 GO:0046697 decidualization(GO:0046697)
0.1 0.7 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 2.9 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.1 0.6 GO:0040016 embryonic cleavage(GO:0040016)
0.1 1.0 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 10.5 GO:0030217 T cell differentiation(GO:0030217)
0.1 0.3 GO:0097052 L-kynurenine metabolic process(GO:0097052)
0.1 5.3 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.1 0.7 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 2.7 GO:0048278 vesicle docking(GO:0048278)
0.1 2.0 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 2.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 1.1 GO:0016180 snRNA processing(GO:0016180)
0.1 1.7 GO:0010332 response to gamma radiation(GO:0010332)
0.1 0.4 GO:0046884 follicle-stimulating hormone secretion(GO:0046884)
0.1 1.2 GO:0042749 regulation of circadian sleep/wake cycle(GO:0042749)
0.1 0.9 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 2.1 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 1.9 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.1 0.6 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 4.4 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.1 0.5 GO:1990001 positive regulation of protein polyubiquitination(GO:1902916) inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.1 1.0 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 1.7 GO:0008206 bile acid metabolic process(GO:0008206)
0.1 0.4 GO:0035745 CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745)
0.1 6.7 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.1 1.2 GO:0038202 TORC1 signaling(GO:0038202)
0.1 2.6 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 2.5 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.1 4.0 GO:0006342 chromatin silencing(GO:0006342)
0.1 1.5 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.1 9.3 GO:0016197 endosomal transport(GO:0016197)
0.0 2.9 GO:0051028 mRNA transport(GO:0051028)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.7 GO:0046037 GMP metabolic process(GO:0046037)
0.0 0.7 GO:0006415 translational termination(GO:0006415)
0.0 4.4 GO:0006486 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 5.7 GO:0030198 extracellular matrix organization(GO:0030198)
0.0 22.9 GO:0006412 translation(GO:0006412)
0.0 5.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.1 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.1 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.2 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 3.2 GO:0045444 fat cell differentiation(GO:0045444)
0.0 0.1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.8 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 1.4 GO:0021549 cerebellum development(GO:0021549)
0.0 0.5 GO:0001510 RNA methylation(GO:0001510)
0.0 0.7 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 22.4 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 11.1 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)
0.0 0.6 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.8 GO:0009408 response to heat(GO:0009408)
0.0 0.4 GO:1902117 positive regulation of organelle assembly(GO:1902117)
0.0 0.2 GO:0008542 visual learning(GO:0008542)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 15.9 GO:0005588 collagen type V trimer(GO:0005588)
3.4 10.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
3.4 10.2 GO:0070821 azurophil granule membrane(GO:0035577) tertiary granule membrane(GO:0070821)
2.6 13.0 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
2.6 10.3 GO:0044393 microspike(GO:0044393)
2.3 6.8 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
2.2 6.5 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
2.1 36.5 GO:0098644 complex of collagen trimers(GO:0098644)
2.1 6.3 GO:0032807 DNA ligase IV complex(GO:0032807)
2.0 10.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
2.0 6.0 GO:0042642 actomyosin, myosin complex part(GO:0042642)
2.0 25.6 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
2.0 17.7 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
1.8 5.3 GO:1990836 lysosomal matrix(GO:1990836)
1.7 9.9 GO:0032280 symmetric synapse(GO:0032280)
1.6 4.8 GO:0033186 CAF-1 complex(GO:0033186)
1.5 6.2 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
1.4 5.4 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
1.2 8.7 GO:0031298 replication fork protection complex(GO:0031298)
1.2 4.7 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
1.2 11.7 GO:0032593 insulin-responsive compartment(GO:0032593)
1.1 11.7 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
1.0 3.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
1.0 5.9 GO:1990393 3M complex(GO:1990393)
1.0 15.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.9 4.7 GO:0097165 nuclear stress granule(GO:0097165)
0.9 26.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.9 3.5 GO:1990005 granular vesicle(GO:1990005)
0.8 2.5 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.8 10.9 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.8 7.7 GO:0031143 pseudopodium(GO:0031143)
0.8 6.8 GO:0005828 kinetochore microtubule(GO:0005828)
0.8 2.3 GO:0034457 Mpp10 complex(GO:0034457)
0.7 15.6 GO:0005865 striated muscle thin filament(GO:0005865)
0.7 13.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.7 12.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.7 5.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.7 18.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.7 5.9 GO:0097512 cardiac myofibril(GO:0097512)
0.6 7.1 GO:0032009 early phagosome(GO:0032009)
0.6 32.2 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.6 1.9 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.6 2.5 GO:0097427 microtubule bundle(GO:0097427)
0.6 41.9 GO:0005811 lipid particle(GO:0005811)
0.6 8.0 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.6 3.3 GO:0001740 Barr body(GO:0001740)
0.5 4.9 GO:0097433 dense body(GO:0097433)
0.5 6.8 GO:0005675 holo TFIIH complex(GO:0005675)
0.5 13.4 GO:0001891 phagocytic cup(GO:0001891)
0.5 9.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.5 6.0 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.5 3.5 GO:0005683 U7 snRNP(GO:0005683)
0.5 1.5 GO:0060187 cell pole(GO:0060187)
0.5 3.8 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.5 1.9 GO:0031417 NatC complex(GO:0031417)
0.5 3.2 GO:0036449 microtubule minus-end(GO:0036449)
0.5 9.2 GO:0005614 interstitial matrix(GO:0005614)
0.4 2.7 GO:0044308 axonal spine(GO:0044308)
0.4 3.1 GO:0042788 polysomal ribosome(GO:0042788)
0.4 12.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.4 10.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.4 12.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.4 6.7 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.4 50.2 GO:0030018 Z disc(GO:0030018)
0.4 37.9 GO:0005884 actin filament(GO:0005884)
0.4 16.6 GO:0009925 basal plasma membrane(GO:0009925)
0.4 4.7 GO:0044666 MLL3/4 complex(GO:0044666)
0.3 3.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.3 9.4 GO:0035371 microtubule plus-end(GO:0035371)
0.3 33.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.3 2.3 GO:0000322 storage vacuole(GO:0000322)
0.3 1.9 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.3 6.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.3 4.1 GO:0016514 SWI/SNF complex(GO:0016514)
0.3 7.6 GO:0042588 zymogen granule(GO:0042588)
0.3 25.0 GO:0005901 caveola(GO:0005901)
0.3 35.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.3 3.4 GO:0030008 TRAPP complex(GO:0030008)
0.3 1.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.3 7.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.3 3.8 GO:0016580 Sin3 complex(GO:0016580)
0.3 1.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.3 1.8 GO:0001739 sex chromatin(GO:0001739)
0.2 1.5 GO:0005663 DNA replication factor C complex(GO:0005663)
0.2 11.2 GO:0005657 replication fork(GO:0005657)
0.2 17.5 GO:0045095 keratin filament(GO:0045095)
0.2 22.0 GO:0005604 basement membrane(GO:0005604)
0.2 8.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 0.7 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.2 5.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.2 13.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 1.5 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.2 1.9 GO:0097539 ciliary transition fiber(GO:0097539)
0.2 11.3 GO:0072686 mitotic spindle(GO:0072686)
0.2 1.5 GO:0001940 male pronucleus(GO:0001940)
0.2 4.9 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.2 2.2 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.2 4.0 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 1.4 GO:0016272 prefoldin complex(GO:0016272)
0.2 11.2 GO:0000786 nucleosome(GO:0000786)
0.2 7.6 GO:0070469 respiratory chain(GO:0070469)
0.2 1.7 GO:0005916 fascia adherens(GO:0005916)
0.2 5.7 GO:0035097 histone methyltransferase complex(GO:0035097)
0.2 2.1 GO:0005845 mRNA cap binding complex(GO:0005845)
0.2 3.7 GO:0044295 axonal growth cone(GO:0044295)
0.2 1.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 3.6 GO:0000145 exocyst(GO:0000145)
0.1 1.2 GO:0031931 TORC1 complex(GO:0031931)
0.1 1.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 5.1 GO:0016235 aggresome(GO:0016235)
0.1 2.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.6 GO:0034657 GID complex(GO:0034657)
0.1 42.6 GO:0005925 focal adhesion(GO:0005925)
0.1 1.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 11.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 0.5 GO:0033269 internode region of axon(GO:0033269)
0.1 6.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 13.3 GO:0000781 chromosome, telomeric region(GO:0000781)
0.1 1.2 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.1 2.1 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 2.7 GO:0000421 autophagosome membrane(GO:0000421)
0.1 1.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 3.5 GO:0060077 inhibitory synapse(GO:0060077)
0.1 6.1 GO:0005643 nuclear pore(GO:0005643)
0.1 6.0 GO:0005776 autophagosome(GO:0005776)
0.1 3.6 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.7 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.8 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 4.0 GO:0030863 cortical cytoskeleton(GO:0030863)
0.1 5.3 GO:0016363 nuclear matrix(GO:0016363)
0.1 0.5 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 2.7 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 28.9 GO:0016607 nuclear speck(GO:0016607)
0.1 4.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 5.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 2.8 GO:0031201 SNARE complex(GO:0031201)
0.1 10.2 GO:0030427 site of polarized growth(GO:0030427)
0.1 2.5 GO:0032420 stereocilium(GO:0032420)
0.1 4.7 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.5 GO:0000178 exosome (RNase complex)(GO:0000178)
0.1 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 3.6 GO:0005882 intermediate filament(GO:0005882)
0.1 1.7 GO:0015935 small ribosomal subunit(GO:0015935)
0.1 1.1 GO:0032039 integrator complex(GO:0032039)
0.1 2.5 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.1 15.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 18.9 GO:0016604 nuclear body(GO:0016604)
0.1 1.0 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 3.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 2.3 GO:0098800 inner mitochondrial membrane protein complex(GO:0098800)
0.1 1.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 1.8 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.1 0.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 9.0 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 1.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 9.9 GO:0005730 nucleolus(GO:0005730)
0.0 0.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.7 GO:0017053 transcriptional repressor complex(GO:0017053)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
10.3 30.8 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
8.5 25.6 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
5.4 26.8 GO:0071987 WD40-repeat domain binding(GO:0071987)
4.6 22.8 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
3.9 19.5 GO:0004974 leukotriene receptor activity(GO:0004974)
3.3 9.9 GO:1990763 arrestin family protein binding(GO:1990763)
2.8 8.5 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
2.6 10.4 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
2.5 7.6 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
2.0 9.9 GO:0050785 advanced glycation end-product receptor activity(GO:0050785)
1.8 7.3 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
1.7 7.0 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
1.7 15.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
1.7 5.2 GO:0030626 U12 snRNA binding(GO:0030626)
1.5 17.0 GO:0019870 potassium channel inhibitor activity(GO:0019870)
1.5 7.5 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
1.4 5.8 GO:0042134 rRNA primary transcript binding(GO:0042134)
1.4 10.1 GO:0043426 MRF binding(GO:0043426)
1.4 5.7 GO:0015265 urea channel activity(GO:0015265)
1.4 5.6 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
1.4 8.3 GO:0051434 BH3 domain binding(GO:0051434)
1.4 5.5 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
1.3 6.7 GO:0032767 copper-exporting ATPase activity(GO:0004008) copper-dependent protein binding(GO:0032767) copper-transporting ATPase activity(GO:0043682)
1.3 5.3 GO:0031686 A1 adenosine receptor binding(GO:0031686)
1.3 11.7 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
1.3 6.3 GO:0045322 unmethylated CpG binding(GO:0045322)
1.2 3.7 GO:0035939 microsatellite binding(GO:0035939)
1.2 4.9 GO:0019002 GMP binding(GO:0019002)
1.2 3.5 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
1.1 6.8 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
1.1 4.5 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
1.1 5.5 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
1.0 8.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
1.0 7.9 GO:0046527 glucosyltransferase activity(GO:0046527)
1.0 7.7 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
1.0 42.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.9 4.7 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.9 3.5 GO:1990955 G-rich single-stranded DNA binding(GO:1990955)
0.8 14.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.8 9.7 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.8 2.3 GO:0008520 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.8 3.8 GO:0005131 growth hormone receptor binding(GO:0005131)
0.8 5.3 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.8 9.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.7 8.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.7 5.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.7 2.8 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.7 45.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.7 4.2 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.7 6.3 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.7 2.0 GO:0001565 phorbol ester receptor activity(GO:0001565)
0.7 8.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.7 3.3 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.6 3.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.6 16.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.6 3.7 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.6 4.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.6 4.8 GO:0070087 chromo shadow domain binding(GO:0070087)
0.6 10.7 GO:0005523 tropomyosin binding(GO:0005523) filamin binding(GO:0031005)
0.6 4.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.6 4.5 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.6 1.7 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.6 1.7 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.5 3.8 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.5 7.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.5 6.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.5 3.8 GO:0003896 DNA primase activity(GO:0003896)
0.5 9.8 GO:0005522 profilin binding(GO:0005522)
0.5 4.9 GO:0030957 Tat protein binding(GO:0030957)
0.5 4.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.5 2.7 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.5 3.7 GO:0097109 neuroligin family protein binding(GO:0097109)
0.5 4.7 GO:0038064 collagen receptor activity(GO:0038064)
0.5 3.0 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.5 2.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.5 3.0 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.5 28.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.5 11.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.5 4.3 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.5 15.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.5 7.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.5 9.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.5 3.3 GO:0000405 bubble DNA binding(GO:0000405)
0.5 2.4 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.5 7.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.5 7.8 GO:0015643 toxic substance binding(GO:0015643)
0.4 19.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.4 1.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.4 9.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.4 5.7 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.4 6.1 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.4 8.9 GO:0042288 MHC class I protein binding(GO:0042288)
0.4 6.0 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.4 7.7 GO:0031489 myosin V binding(GO:0031489)
0.3 3.1 GO:0042608 T cell receptor binding(GO:0042608)
0.3 2.0 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.3 8.5 GO:0051393 alpha-actinin binding(GO:0051393)
0.3 2.9 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.3 7.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.3 3.0 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.3 1.5 GO:0001595 angiotensin receptor activity(GO:0001595)
0.3 5.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.3 28.2 GO:0019905 syntaxin binding(GO:0019905)
0.3 1.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.3 2.0 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.3 2.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.3 3.1 GO:0008097 5S rRNA binding(GO:0008097)
0.3 3.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.3 12.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.3 1.5 GO:0004568 chitinase activity(GO:0004568)
0.2 1.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 4.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.2 4.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 29.0 GO:0030674 protein binding, bridging(GO:0030674)
0.2 1.7 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.2 6.4 GO:0017091 AU-rich element binding(GO:0017091)
0.2 0.7 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.2 64.7 GO:0030246 carbohydrate binding(GO:0030246)
0.2 25.8 GO:0017124 SH3 domain binding(GO:0017124)
0.2 8.6 GO:0004180 carboxypeptidase activity(GO:0004180)
0.2 0.7 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.2 1.3 GO:0000150 recombinase activity(GO:0000150)
0.2 1.0 GO:0008061 chitin binding(GO:0008061)
0.2 15.7 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.2 67.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.2 51.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 3.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 4.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.2 6.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 1.8 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.2 9.2 GO:0005518 collagen binding(GO:0005518)
0.2 6.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 3.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.2 2.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 5.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 1.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.2 14.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 2.7 GO:0004697 protein kinase C activity(GO:0004697)
0.2 33.6 GO:0042393 histone binding(GO:0042393)
0.2 0.7 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.2 4.3 GO:0050681 androgen receptor binding(GO:0050681)
0.2 41.6 GO:0005096 GTPase activator activity(GO:0005096)
0.2 0.8 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.2 5.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 1.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.2 2.2 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.2 2.3 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 2.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.3 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.1 1.5 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 5.7 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.1 2.5 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.7 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.1 1.2 GO:0003924 GTPase activity(GO:0003924)
0.1 1.9 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 1.8 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 2.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 2.2 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 4.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 5.5 GO:0000049 tRNA binding(GO:0000049)
0.1 6.4 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.1 4.4 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 1.0 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 40.2 GO:0005525 GTP binding(GO:0005525)
0.1 1.0 GO:0000182 rDNA binding(GO:0000182)
0.1 7.3 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 10.8 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 11.6 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.1 5.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 2.9 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 1.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 11.0 GO:0044325 ion channel binding(GO:0044325)
0.1 1.6 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.1 6.0 GO:0009055 electron carrier activity(GO:0009055)
0.1 3.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.9 GO:0008198 ferrous iron binding(GO:0008198)
0.1 0.6 GO:0003916 DNA topoisomerase activity(GO:0003916) DNA topoisomerase type I activity(GO:0003917) supercoiled DNA binding(GO:0097100)
0.1 22.1 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 4.3 GO:0051117 ATPase binding(GO:0051117)
0.1 14.0 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.1 4.4 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.1 5.0 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 5.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 2.2 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 0.6 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 3.7 GO:0008186 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 2.1 GO:0042605 peptide antigen binding(GO:0042605)
0.1 0.9 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 0.8 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 1.8 GO:0043022 ribosome binding(GO:0043022)
0.0 0.7 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 2.8 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 1.2 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.6 GO:0070840 dynein complex binding(GO:0070840)
0.0 2.5 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 3.2 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 5.3 GO:0045296 cadherin binding(GO:0045296)
0.0 3.5 GO:0000287 magnesium ion binding(GO:0000287)
0.0 1.5 GO:0002020 protease binding(GO:0002020)
0.0 37.8 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 1.9 GO:0051020 GTPase binding(GO:0051020)
0.0 0.1 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.9 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.7 GO:0019955 cytokine binding(GO:0019955)
0.0 0.5 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 1.1 GO:0008047 enzyme activator activity(GO:0008047)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 7.0 PID LPA4 PATHWAY LPA4-mediated signaling events
1.2 27.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
1.1 44.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.8 22.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.8 35.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.7 3.5 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.7 35.7 PID PI3KCI PATHWAY Class I PI3K signaling events
0.5 24.8 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.5 42.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.5 15.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.5 22.3 PID AP1 PATHWAY AP-1 transcription factor network
0.5 27.1 PID ENDOTHELIN PATHWAY Endothelins
0.5 20.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.4 7.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.4 7.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.4 6.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.4 11.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.4 6.7 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.4 4.3 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.4 15.9 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.4 3.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.4 9.9 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.4 19.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.4 15.8 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.3 12.7 PID TNF PATHWAY TNF receptor signaling pathway
0.3 10.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.3 11.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.3 3.9 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.3 4.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.3 2.7 PID IGF1 PATHWAY IGF1 pathway
0.3 3.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.3 15.4 PID NOTCH PATHWAY Notch signaling pathway
0.2 11.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 9.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 3.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.2 9.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 5.4 PID BARD1 PATHWAY BARD1 signaling events
0.2 9.1 PID P53 REGULATION PATHWAY p53 pathway
0.2 5.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.2 7.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 11.0 PID CMYB PATHWAY C-MYB transcription factor network
0.2 3.6 PID INSULIN PATHWAY Insulin Pathway
0.2 7.6 PID BMP PATHWAY BMP receptor signaling
0.2 6.0 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.1 2.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 20.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.4 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 2.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 2.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 2.4 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 4.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 2.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.6 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 3.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 3.1 PID ATR PATHWAY ATR signaling pathway
0.1 21.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 1.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 59.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
1.6 22.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
1.4 19.5 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
1.3 7.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
1.1 12.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
1.0 15.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.9 24.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.8 7.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.8 7.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.8 15.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.8 10.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.7 9.9 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.7 5.7 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.7 10.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.7 28.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.7 11.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.7 8.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.7 6.5 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.6 7.0 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.6 6.3 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.6 5.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.6 4.9 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.6 30.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.6 5.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.5 13.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.5 9.2 REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.5 10.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.5 8.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.4 3.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.4 6.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.4 9.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.4 6.6 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.4 11.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.4 4.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.4 8.4 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.4 9.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.3 37.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.3 8.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.3 10.9 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.3 3.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.3 5.5 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.3 3.8 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.3 3.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.3 8.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3 4.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.3 3.8 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.3 2.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.3 23.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.3 5.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.3 10.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.3 6.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2 4.7 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.2 11.2 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.2 6.3 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.2 22.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.2 8.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 14.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.2 2.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 6.3 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.2 2.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.2 2.9 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.2 2.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.2 3.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 3.8 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.2 8.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2 5.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.2 7.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.2 2.4 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.2 6.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.2 4.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 6.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.2 3.8 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.2 2.9 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 15.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 5.1 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 6.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.5 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.1 1.9 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.7 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1 1.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 2.0 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 2.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.2 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 1.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 2.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 4.1 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 1.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 2.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.9 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.5 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0 2.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 2.1 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 4.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases