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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Hoxa11_Hoxc12

Z-value: 0.54

Motif logo

Transcription factors associated with Hoxa11_Hoxc12

Gene Symbol Gene ID Gene Info
ENSRNOG00000059870 homeobox A11
ENSRNOG00000053884 homeobox A11
ENSRNOG00000016116 homeo box C12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxa11rn6_v1_chr4_-_82215022_822150220.242.0e-05Click!
Hoxc12rn6_v1_chr7_+_144547939_1445479390.081.3e-01Click!

Activity profile of Hoxa11_Hoxc12 motif

Sorted Z-values of Hoxa11_Hoxc12 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_152533349 25.23 ENSRNOT00000067524
tripartite motif containing 63
chr4_+_14151343 18.36 ENSRNOT00000061687
ENSRNOT00000076573
ENSRNOT00000077219
ENSRNOT00000008319
CD36 molecule
chr1_+_201055644 16.97 ENSRNOT00000054937
ENSRNOT00000047161
transforming, acidic coiled-coil containing protein 2
chr9_-_73958480 15.60 ENSRNOT00000017838
myosin, light chain 1
chr8_-_55087832 14.69 ENSRNOT00000032152
dihydrolipoamide S-acetyltransferase
chr3_+_53563194 13.64 ENSRNOT00000048300
xin actin-binding repeat containing 2
chr4_-_159192526 10.94 ENSRNOT00000026731
potassium voltage-gated channel subfamily A member 1
chr19_-_22194740 10.02 ENSRNOT00000086187
phosphorylase kinase regulatory subunit beta
chr4_-_82209933 9.43 ENSRNOT00000091106
homeobox protein Hox-A10-like
chrX_+_121612952 9.32 ENSRNOT00000022122

chr10_-_104179523 9.19 ENSRNOT00000005292
solute carrier family 25 member 19
chr4_-_82295470 9.17 ENSRNOT00000091073
homeobox A10
chr1_+_8310577 7.24 ENSRNOT00000015131
human immunodeficiency virus type I enhancer binding protein 2
chr4_+_14071507 7.22 ENSRNOT00000066224
ENSRNOT00000075962
CD36 molecule
similar to fatty acid translocase/CD36
chr2_-_18565842 7.18 ENSRNOT00000067456
ENSRNOT00000063821
ENSRNOT00000045532
versican
chrX_+_131617798 6.88 ENSRNOT00000074384
proline rich 32
chr1_-_93949187 6.79 ENSRNOT00000018956
zinc finger protein 536
chr13_-_51297621 6.41 ENSRNOT00000030926
NADH:ubiquinone oxidoreductase subunit V3
chr5_-_154332940 6.36 ENSRNOT00000014458
PITH domain containing 1
chr16_+_81587446 5.83 ENSRNOT00000092680
DCN1, defective in cullin neddylation 1, domain containing 2
chr4_-_82202096 5.56 ENSRNOT00000081824
homeobox protein Hox-A10-like
chrX_+_42951237 5.36 ENSRNOT00000060113
similar to vitellogenin-like 1 precursor
chr1_-_211265161 5.32 ENSRNOT00000080041
ENSRNOT00000023477
BCL2 interacting protein 3
chr1_-_53038229 5.15 ENSRNOT00000017282
mitochondrial pyruvate carrier 1
chr4_-_34194764 5.10 ENSRNOT00000045270
collagen type XXVIII alpha 1 chain
chr10_+_14543200 4.46 ENSRNOT00000047111
RGD1565784
chr9_+_50526811 4.46 ENSRNOT00000036990
similar to RIKEN cDNA 1500015O10
chr1_+_94718402 4.44 ENSRNOT00000046035
ubiquinol-cytochrome c reductase binding protein
chr7_-_11963268 4.25 ENSRNOT00000080342
ENSRNOT00000025266
casein kinase 1, gamma 2
chr1_-_207811008 3.62 ENSRNOT00000080506
clarin 3
chr6_+_18970564 3.59 ENSRNOT00000090121
ENSRNOT00000030803
CWF19-like 2, cell cycle control (S. pombe)
chr1_-_169721758 3.49 ENSRNOT00000023213
ubiquitin carboxyl-terminal hydrolase DUB-1-like
chrX_+_110007214 3.32 ENSRNOT00000093539
Nik related kinase
chr9_+_64745051 3.24 ENSRNOT00000021527
spermatogenesis associated, serine-rich 2-like
chr5_-_156734541 3.19 ENSRNOT00000021036
cytidine deaminase-like
chr11_-_61470046 3.17 ENSRNOT00000073436
N-alpha-acetyltransferase 50-like
chr11_-_4397361 3.11 ENSRNOT00000046370
cell adhesion molecule 2
chr17_+_77195247 3.08 ENSRNOT00000081940
optineurin
chr4_-_56493923 2.61 ENSRNOT00000027173
inosine monophosphate dehydrogenase 1
chr10_-_88009576 2.55 ENSRNOT00000018566
keratin 35
chr2_+_230901126 2.44 ENSRNOT00000016026
ENSRNOT00000015564
ENSRNOT00000068198
calcium/calmodulin-dependent protein kinase II delta
chr16_-_20511818 2.37 ENSRNOT00000026567
LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
chr5_+_122019301 2.35 ENSRNOT00000068158
phosphodiesterase 4B
chr6_-_105160470 2.28 ENSRNOT00000008367
a disintegrin and metalloprotease domain 4
chr5_+_154489590 2.21 ENSRNOT00000035788
inhibitor of DNA binding 3, HLH protein
chr11_+_60371729 2.20 ENSRNOT00000058453
Cd200 molecule
chr9_-_69960086 2.16 ENSRNOT00000072737
G protein-coupled receptor 1
chr10_-_29196563 2.15 ENSRNOT00000005205
fatty acid binding protein 6
chr7_-_143453544 2.13 ENSRNOT00000034450
ENSRNOT00000083956
keratin 1
keratin 5
chr5_+_127489418 2.03 ENSRNOT00000065275
similar to RIKEN cDNA 0610037L13
chr3_-_103345333 2.03 ENSRNOT00000071479
olfactory receptor 4F3/4F16/4F29-like
chr3_+_11593655 1.98 ENSRNOT00000074122
phosphatidylinositol-4-phosphate 5-kinase-like 1
chr4_-_82173207 1.94 ENSRNOT00000074167
homeo box A5
chrX_+_106306795 1.90 ENSRNOT00000073661
G protein-coupled receptor associated sorting protein 1
chr4_+_123760743 1.81 ENSRNOT00000013498
coiled-coil domain containing 174
chr5_+_33784715 1.78 ENSRNOT00000035685
solute carrier family 7 member 13
chr1_-_193700673 1.78 ENSRNOT00000071314
polyadenylate-binding protein-interacting protein 2-like 1
chr16_-_64745207 1.77 ENSRNOT00000032467
TELO2 interacting protein 2
chr4_+_10748745 1.70 ENSRNOT00000046142
round spermatid basic protein 1-like
chr10_+_57131386 1.67 ENSRNOT00000026507
proteasome subunit beta 6
chr4_-_100213858 1.66 ENSRNOT00000015562
ubiquitin specific peptidase 39
chr18_-_81428971 1.60 ENSRNOT00000065201
zinc finger protein 407
chr16_-_81587076 1.57 ENSRNOT00000092470
ENSRNOT00000092721
transmembrane and coiled-coil domain-containing protein 3
chr4_+_183656013 1.55 ENSRNOT00000055442
electron transfer flavoprotein beta subunit lysine methyltransferase
chr5_-_60559533 1.55 ENSRNOT00000092899
zinc finger and BTB domain containing 5
chr2_+_18354542 1.54 ENSRNOT00000042958
hyaluronan and proteoglycan link protein 1
chr16_+_80904125 1.52 ENSRNOT00000080832
transmembrane and coiled-coil domains 3
chr11_+_28945575 1.50 ENSRNOT00000061600
ENSRNOT00000090364

chr8_+_67615635 1.49 ENSRNOT00000008971
integrin subunit alpha 11
chr3_+_140106766 1.48 ENSRNOT00000014046
N(alpha)-acetyltransferase 20, NatB catalytic subunit
chr3_-_103400272 1.48 ENSRNOT00000046527
olfactory receptor 790
chr7_-_15852930 1.45 ENSRNOT00000009270
similar to zinc finger protein 101
chr7_-_11754508 1.44 ENSRNOT00000026341
ornithine decarboxylase antizyme 1
chr2_+_196655469 1.38 ENSRNOT00000028730
cathepsin K
chr3_-_77127190 1.33 ENSRNOT00000007996
olfactory receptor 652
chr1_-_168611670 1.33 ENSRNOT00000021273
olfactory receptor 106
chr6_-_51019407 1.33 ENSRNOT00000011659
G protein-coupled receptor 22
chr3_-_103128243 1.23 ENSRNOT00000046310
olfactory receptor 779
chr4_+_66276835 1.22 ENSRNOT00000007544
formation of mitochondrial complex V assembly factor 1
chr14_+_46001849 1.21 ENSRNOT00000076611
RELT-like 1
chr9_-_112027155 1.17 ENSRNOT00000021258
ENSRNOT00000080962
praja ring finger ubiquitin ligase 2
chr8_-_119219232 1.15 ENSRNOT00000040840
teratocarcinoma-derived growth factor 1
chr15_-_49005058 1.15 ENSRNOT00000019262
elongator acetyltransferase complex subunit 3
chr11_-_70211701 1.04 ENSRNOT00000076114
mucin 13, cell surface associated
chr2_+_186630278 1.02 ENSRNOT00000021604
similar to elongation protein 4 homolog
chr15_-_37831031 1.01 ENSRNOT00000091562
eukaryotic translation elongation factor 1 alpha lysine methyltransferase 1
chr11_-_28842287 0.97 ENSRNOT00000061610
keratin associated protein 19-5
chr17_+_47302272 0.95 ENSRNOT00000090021
NME/NM23 family member 8
chr1_-_60332899 0.92 ENSRNOT00000078636
vomeronasal type-1 receptor 4-like
chr7_-_52404774 0.92 ENSRNOT00000082100
neuron navigator 3
chr15_-_27032498 0.92 ENSRNOT00000016702
olfactory receptor 1609
chr13_+_52887649 0.92 ENSRNOT00000048033
achaete-scute family bHLH transcription factor 5
chr8_+_115131367 0.91 ENSRNOT00000014849
ribosomal protein L29
chr10_+_64336200 0.90 ENSRNOT00000046519
ribosomal protein L37
chr5_+_2043583 0.89 ENSRNOT00000082813
elongin C
chr2_-_189333015 0.84 ENSRNOT00000076424
ENSRNOT00000076952
HCLS1 associated protein X-1
chr2_-_189333322 0.84 ENSRNOT00000073599
ENSRNOT00000071253
ENSRNOT00000076325
HCLS1 associated protein X-1
chr6_+_54417903 0.81 ENSRNOT00000052356
phosphoribosyl pyrophosphate synthetase 1-like 1
chr18_-_37776453 0.80 ENSRNOT00000087876
dihydropyrimidinase-like 3
chr10_+_60231027 0.80 ENSRNOT00000085543
olfactory receptor 1482
chr8_+_99568958 0.78 ENSRNOT00000073400
phospholipid scramblase family, member 5
chr4_-_162498052 0.76 ENSRNOT00000066349
chromobox homolog 3-like
chr10_-_29196252 0.74 ENSRNOT00000083910
fatty acid binding protein 6
chr2_+_159138758 0.73 ENSRNOT00000087942

chr16_-_16762240 0.73 ENSRNOT00000080746

chr5_-_156781291 0.73 ENSRNOT00000075128
cytidine deaminase
chr7_-_97994586 0.72 ENSRNOT00000077616
WDYHV motif containing 1
chr4_-_82258765 0.72 ENSRNOT00000008523
homeo box A5
chr1_-_60517915 0.72 ENSRNOT00000078071
vomeronasal 1 receptor 11
chr8_+_45061670 0.70 ENSRNOT00000028909
brain specific homeobox
chr3_-_78663607 0.70 ENSRNOT00000073134
olfactory receptor 718
chr9_-_17880706 0.70 ENSRNOT00000031549
alanyl-tRNA synthetase 2, mitochondrial
chr10_-_83128297 0.69 ENSRNOT00000082160
lysine acetyltransferase 7
chr15_+_26033791 0.68 ENSRNOT00000020074
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chrX_+_111735820 0.68 ENSRNOT00000086948
FERM and PDZ domain containing 3
chr1_-_149859479 0.68 ENSRNOT00000052199
olfactory receptor 14A2-like
chr3_-_77677349 0.67 ENSRNOT00000084989
olfactory receptor 669
chr1_-_149675443 0.67 ENSRNOT00000086084
olfactory receptor 294
chr3_-_103265059 0.64 ENSRNOT00000073965
putative olfactory receptor GPCRLTM7
chr1_+_68239314 0.64 ENSRNOT00000070823
vomeronasal 1 receptor 109
chr1_-_174379566 0.62 ENSRNOT00000067388
TMEM9 domain family, member B
chr11_+_73693814 0.62 ENSRNOT00000081081
ENSRNOT00000002354
ENSRNOT00000090940
large 60S subunit nuclear export GTPase 1
chr10_-_44659707 0.61 ENSRNOT00000002064
similar to Alpha enolase (2-phospho-D-glycerate hydro-lyase)
chr2_+_166403265 0.61 ENSRNOT00000012417
NMD3 ribosome export adaptor
chr14_-_21898284 0.60 ENSRNOT00000036314
proline rich 27
chr1_-_149770781 0.56 ENSRNOT00000082185
olfactory receptor 16
chr6_-_92007917 0.56 ENSRNOT00000006425
ENSRNOT00000089891
SOS Ras/Rho guanine nucleotide exchange factor 2
chr14_+_812382 0.55 ENSRNOT00000041506
ENSRNOT00000039993

chrX_+_104734082 0.54 ENSRNOT00000005020
sushi-repeat-containing protein, X-linked 2
chr11_-_782954 0.52 ENSRNOT00000040065
Eph receptor A3
chr8_+_48727618 0.51 ENSRNOT00000029546
ribosomal protein s25
chr3_-_76102782 0.51 ENSRNOT00000007690
olfactory receptor 602
chr3_-_73484676 0.51 ENSRNOT00000040041
olfactory receptor 481
chr1_+_65906344 0.50 ENSRNOT00000068611
vomeronasal 2 receptor, 34
chr7_-_3123297 0.49 ENSRNOT00000061878
RAB5B, member RAS oncogene family
chr10_+_92245442 0.49 ENSRNOT00000006808
signal peptide peptidase like 2C
chr14_+_900696 0.47 ENSRNOT00000049544
vomeronasal 2 receptor, 71
chr6_-_51018050 0.45 ENSRNOT00000082691
G protein-coupled receptor 22
chr14_-_3288017 0.43 ENSRNOT00000080452
hypothetical protein LOC689986
chr19_-_19727081 0.43 ENSRNOT00000020700
adenylate cyclase 7
chr14_-_44375804 0.42 ENSRNOT00000042825
ribosomal protein P2-like
chr7_-_119200623 0.41 ENSRNOT00000029753
eukaryotic translation initiation factor 3, subunit D
chr1_-_150173316 0.39 ENSRNOT00000044676
olfactory receptor 27
chr10_-_109622745 0.39 ENSRNOT00000074354
ENSRNOT00000088317
phosphodiesterase 6G
chr10_+_63884338 0.36 ENSRNOT00000007100
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
chr2_+_187993758 0.36 ENSRNOT00000027182
Rho/Rac guanine nucleotide exchange factor 2
chr16_-_62294769 0.35 ENSRNOT00000020663
protein phosphatase 2 catalytic subunit beta
chr14_+_4362717 0.35 ENSRNOT00000002887
BarH-like homeobox 2
chr1_+_172157739 0.34 ENSRNOT00000044619
olfactory receptor 242
chr8_-_36388224 0.34 ENSRNOT00000038312
TIR domain containing adaptor protein
chr17_+_82430836 0.34 ENSRNOT00000083164
MAM and LDL receptor class A domain containing 1
chr3_+_161178117 0.32 ENSRNOT00000051826
serine peptidase inhibitor, Kunitz type 5
chr17_+_47301511 0.30 ENSRNOT00000092051
ENSRNOT00000087178
NME/NM23 family member 8
chr6_+_27535020 0.28 ENSRNOT00000076512
adhesion G protein-coupled receptor F3
chr5_-_147584038 0.28 ENSRNOT00000010983
zinc finger and BTB domain containing 8a
chr7_+_7068703 0.28 ENSRNOT00000074567
olfactory receptor 1012
chr14_+_83889089 0.28 ENSRNOT00000078980
MORC family CW-type zinc finger 2
chr3_+_78876609 0.26 ENSRNOT00000049936
olfactory receptor 726
chr1_-_150262213 0.25 ENSRNOT00000049595
olfactory receptor 32
chr3_-_77170085 0.23 ENSRNOT00000042667
olfactory receptor 654
chr3_-_74749960 0.22 ENSRNOT00000046197
olfactory receptor 491
chr10_+_29606748 0.21 ENSRNOT00000080720

chr8_+_1459526 0.20 ENSRNOT00000034503
kelch repeat and BTB domain containing 3
chr2_-_250862419 0.19 ENSRNOT00000017943
chloride channel accessory 4
chr8_+_41987849 0.19 ENSRNOT00000073800
olfactory receptor 143-like
chr8_+_41350182 0.17 ENSRNOT00000072823
olfactory receptor 143-like
chr14_-_194072 0.17 ENSRNOT00000073973
vomeronasal 2, receptor 112
chr14_-_89238094 0.17 ENSRNOT00000006818
Sad1 and UNC84 domain containing 3
chr12_+_51937175 0.16 ENSRNOT00000056780
pseudouridylate synthase 1
chr1_-_150210403 0.14 ENSRNOT00000081156
olfactory receptor 29
chr2_+_166856784 0.13 ENSRNOT00000035765
otolin 1
chr2_+_257626383 0.13 ENSRNOT00000080993
zinc finger, ZZ-type containing 3
chrX_-_79066932 0.13 ENSRNOT00000057460
similar to WASP family 1
chr1_-_59903339 0.13 ENSRNOT00000039037
formyl peptide receptor, related sequence 3
chr8_-_115263484 0.11 ENSRNOT00000039696
ENSRNOT00000081138
IQ motif containing F3
chr3_+_73235594 0.08 ENSRNOT00000082357
olfactory receptor 463
chr20_-_6556350 0.08 ENSRNOT00000035819
LEM domain containing 2
chr3_-_78429583 0.08 ENSRNOT00000042658
olfactory receptor 705
chr1_-_168310071 0.08 ENSRNOT00000044675
olfactory receptor 82
chr8_+_82380757 0.08 ENSRNOT00000013512
LEO1 homolog, Paf1/RNA polymerase II complex component
chr3_-_75576520 0.07 ENSRNOT00000083330
olfactory receptor 567
chr16_+_2706428 0.06 ENSRNOT00000077117
interleukin 17 receptor D
chr16_+_24980723 0.03 ENSRNOT00000082142
translation machinery associated 16 homolog
chr9_+_67699379 0.03 ENSRNOT00000091237
ENSRNOT00000088183
cytotoxic T-lymphocyte-associated protein 4
chr11_-_43358275 0.03 ENSRNOT00000060891
olfactory receptor 1542

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxa11_Hoxc12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 25.2 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
4.3 25.6 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
3.1 9.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
2.2 10.9 GO:0050975 sensory perception of touch(GO:0050975)
1.7 5.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
1.3 14.7 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
1.3 5.3 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
1.2 3.5 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
1.1 17.0 GO:0030953 astral microtubule organization(GO:0030953)
0.9 2.7 GO:0060764 cell-cell signaling involved in mammary gland development(GO:0060764)
0.8 2.4 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.8 3.9 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.8 6.8 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.6 4.4 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.6 3.3 GO:0060723 regulation of spongiotrophoblast cell proliferation(GO:0060721) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.5 2.6 GO:0006177 GMP biosynthetic process(GO:0006177)
0.5 4.5 GO:0070314 G1 to G0 transition(GO:0070314)
0.5 1.4 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.4 2.4 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.4 3.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.4 2.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.3 1.5 GO:1904732 regulation of electron carrier activity(GO:1904732)
0.3 5.0 GO:1902572 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.2 9.2 GO:0060065 uterus development(GO:0060065)
0.2 2.2 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.2 0.7 GO:0072720 response to dithiothreitol(GO:0072720)
0.2 1.4 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.2 13.4 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.2 0.7 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.2 0.5 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.1 0.4 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 1.7 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 1.3 GO:0006183 GTP biosynthetic process(GO:0006183)
0.1 0.4 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1 2.4 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.1 0.3 GO:2000338 chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.1 6.4 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.1 7.2 GO:0031103 axon regeneration(GO:0031103)
0.1 13.7 GO:0060048 cardiac muscle contraction(GO:0060048)
0.1 0.6 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.1 2.2 GO:0030903 notochord development(GO:0030903)
0.1 1.2 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.6 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.1 1.9 GO:0032801 receptor catabolic process(GO:0032801)
0.1 0.4 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 2.1 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 1.1 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1 7.7 GO:0044042 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.1 0.3 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.1 1.5 GO:0038065 collagen-activated signaling pathway(GO:0038065)
0.1 1.0 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.5 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.1 0.8 GO:0051764 actin crosslink formation(GO:0051764)
0.1 1.2 GO:0035329 hippo signaling(GO:0035329)
0.0 0.5 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.7 GO:0060056 mammary gland involution(GO:0060056)
0.0 1.0 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 1.6 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 2.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 4.2 GO:0008360 regulation of cell shape(GO:0008360)
0.0 2.3 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 1.2 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 1.3 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 2.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.5 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.4 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 1.1 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 0.4 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 1.7 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.8 GO:0009156 ribonucleoside monophosphate biosynthetic process(GO:0009156)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 2.9 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 14.7 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
1.3 10.0 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.8 25.2 GO:0031430 M band(GO:0031430)
0.7 10.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.5 14.3 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.4 4.4 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.3 2.4 GO:0005688 U6 snRNP(GO:0005688)
0.3 15.6 GO:0016459 myosin complex(GO:0016459)
0.2 21.4 GO:0031526 brush border membrane(GO:0031526)
0.2 1.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.2 1.3 GO:0036157 outer dynein arm(GO:0036157) sperm cytoplasmic droplet(GO:0097598)
0.2 5.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.2 0.7 GO:0031417 NatC complex(GO:0031417)
0.2 1.5 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.1 2.4 GO:0043194 axon initial segment(GO:0043194)
0.1 0.9 GO:0070449 elongin complex(GO:0070449)
0.1 6.4 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 16.0 GO:0030018 Z disc(GO:0030018)
0.1 0.9 GO:0042788 polysomal ribosome(GO:0042788)
0.1 3.1 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 2.1 GO:0001533 cornified envelope(GO:0001533)
0.1 0.5 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 1.7 GO:0005839 proteasome core complex(GO:0005839)
0.1 0.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 1.5 GO:0008305 integrin complex(GO:0008305)
0.0 0.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 3.1 GO:0005776 autophagosome(GO:0005776)
0.0 10.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 3.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.8 GO:0031941 filamentous actin(GO:0031941)
0.0 3.5 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 5.7 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.5 GO:0005844 polysome(GO:0005844)
0.0 0.6 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 1.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 25.6 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
3.1 9.2 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
2.0 27.7 GO:0031432 titin binding(GO:0031432)
1.8 14.7 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
1.3 10.0 GO:0004689 phosphorylase kinase activity(GO:0004689)
1.0 5.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.8 6.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.7 3.9 GO:0004126 cytidine deaminase activity(GO:0004126)
0.6 3.1 GO:0001155 TFIIIA-class transcription factor binding(GO:0001155)
0.6 4.4 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.5 1.4 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.5 10.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.5 2.4 GO:0042731 PH domain binding(GO:0042731)
0.4 2.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.4 7.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.4 1.1 GO:0038100 nodal binding(GO:0038100) type I activin receptor binding(GO:0070698)
0.4 1.1 GO:0010484 phosphorylase kinase regulator activity(GO:0008607) H3 histone acetyltransferase activity(GO:0010484)
0.4 1.5 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.3 13.6 GO:0051393 alpha-actinin binding(GO:0051393)
0.3 2.9 GO:0032052 bile acid binding(GO:0032052)
0.2 2.0 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.2 0.7 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.2 3.1 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.2 2.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 1.7 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 2.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.3 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.1 0.8 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.8 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 16.0 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.1 10.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.2 GO:0042923 neuropeptide binding(GO:0042923)
0.1 8.6 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 1.9 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 1.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 1.7 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.5 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.4 GO:0043394 proteoglycan binding(GO:0043394)
0.0 2.6 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.4 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.4 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0 3.3 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 1.8 GO:0015297 antiporter activity(GO:0015297)
0.0 2.3 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 2.0 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)
0.0 0.1 GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269)
0.0 2.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 17.0 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.9 GO:0019843 rRNA binding(GO:0019843)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.3 9.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 1.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 6.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 5.1 NABA COLLAGENS Genes encoding collagen proteins
0.1 4.3 PID FOXO PATHWAY FoxO family signaling
0.1 5.3 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 2.4 PID IFNG PATHWAY IFN-gamma pathway
0.1 1.5 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.4 PID AURORA A PATHWAY Aurora A signaling
0.0 0.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 2.3 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.4 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.7 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 13.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.5 7.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.5 10.0 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.4 15.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.4 27.2 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.2 2.9 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 2.6 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 10.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.2 1.4 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.2 2.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.2 10.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.2 2.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 25.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 1.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 3.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 5.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.8 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 2.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects