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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Hoxa10

Z-value: 0.87

Motif logo

Transcription factors associated with Hoxa10

Gene Symbol Gene ID Gene Info
ENSRNOG00000057650 homeobox A10

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxa10rn6_v1_chr4_-_82295470_82295470-0.382.2e-12Click!

Activity profile of Hoxa10 motif

Sorted Z-values of Hoxa10 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_14151343 32.06 ENSRNOT00000061687
ENSRNOT00000076573
ENSRNOT00000077219
ENSRNOT00000008319
CD36 molecule
chr1_-_197821936 24.05 ENSRNOT00000055027
CD19 molecule
chr11_-_54514441 23.13 ENSRNOT00000002673
resistin-like gamma
chr4_+_98370797 22.28 ENSRNOT00000031991

chr2_+_88217188 21.91 ENSRNOT00000014267
carbonic anhydrase I
chr6_-_140880070 20.40 ENSRNOT00000073779
uncharacterized LOC691828
chr4_+_14071507 20.35 ENSRNOT00000066224
ENSRNOT00000075962
CD36 molecule
similar to fatty acid translocase/CD36
chr4_+_14213587 18.97 ENSRNOT00000067543
platelet glycoprotein 4-like
chr7_+_83373022 18.78 ENSRNOT00000057146
ENSRNOT00000005958
polycystic kidney and hepatic disease 1-like 1
chr5_-_58198782 17.32 ENSRNOT00000023951
C-C motif chemokine ligand 21
chr14_-_62595854 17.07 ENSRNOT00000003024
Yip1 domain family, member 7
chr18_-_77317969 17.03 ENSRNOT00000090369
nuclear factor of activated T-cells 1
chr3_+_18315320 15.82 ENSRNOT00000006954

chr4_-_163445302 14.89 ENSRNOT00000087106
killer cell lectin-like receptor subfamily C, member 3
chr11_+_85263536 14.77 ENSRNOT00000046465

chr3_+_173969273 14.60 ENSRNOT00000083970
cadherin 26
chr8_+_96551245 13.73 ENSRNOT00000039850
BCL2-related protein A1
chr1_+_168945449 13.51 ENSRNOT00000087661
ENSRNOT00000019913
hemoglobin subunit beta-2-like
chr2_+_248398917 13.42 ENSRNOT00000045855
guanylate binding protein 1
chr3_-_118635268 13.20 ENSRNOT00000086357
ATPase phospholipid transporting 8B4 (putative)
chr11_+_57108956 12.69 ENSRNOT00000035485
CD96 molecule
chr5_-_115387377 12.65 ENSRNOT00000036030
ENSRNOT00000077492
similar to hypothetical protein MGC34837
chr5_+_61657507 12.20 ENSRNOT00000013228
tropomodulin 1
chr11_-_45124423 12.09 ENSRNOT00000046383
filamin A interacting protein 1-like
chr13_+_53351717 11.43 ENSRNOT00000012038
kinesin family member 14
chr4_-_165192647 11.18 ENSRNOT00000086461
killer cell lectin-like receptor, subfamily A, member 5
chr11_+_85508300 10.95 ENSRNOT00000038646

chr3_-_60166013 10.05 ENSRNOT00000024922
WAS/WASL interacting protein family, member 1
chr10_-_67401836 9.87 ENSRNOT00000073071
cytokine receptor-like factor 3
chr11_-_60819249 9.28 ENSRNOT00000043917
ENSRNOT00000042447
CD200 receptor 1-like
chr16_-_48692476 9.19 ENSRNOT00000013118
interferon regulatory factor 2
chr4_-_103024841 9.08 ENSRNOT00000090283

chr4_+_61924013 8.97 ENSRNOT00000090717
bisphosphoglycerate mutase
chr2_+_231941794 8.64 ENSRNOT00000091475

chr13_+_90116843 8.60 ENSRNOT00000006306
Cd48 molecule
chr6_-_140715174 8.46 ENSRNOT00000085345

chr17_+_81922329 8.44 ENSRNOT00000031542
calcium voltage-gated channel auxiliary subunit beta 2
chr17_-_86657473 8.23 ENSRNOT00000078827

chr6_+_55465782 8.09 ENSRNOT00000006682
anterior gradient 2, protein disulphide isomerase family member
chr4_+_162493908 7.61 ENSRNOT00000072064
C-type lectin domain family 2, member D
chr10_+_87759769 7.13 ENSRNOT00000017378
ENSRNOT00000046526
keratin associated protein 9-1
chrX_-_104984341 7.03 ENSRNOT00000077996
XK related, X-linked
chr4_+_69386698 6.81 ENSRNOT00000091655
T cell receptor beta, variable 13-2
chr20_+_6351458 6.68 ENSRNOT00000091731
cyclin-dependent kinase inhibitor 1A
chr2_+_231884337 6.57 ENSRNOT00000014695
zinc finger, GRF-type containing 1
chr9_-_65736852 6.53 ENSRNOT00000087458
trafficking kinesin protein 2
chr8_+_117347029 6.45 ENSRNOT00000047717
inosine monophosphate dehydrogenase 2
chr16_-_7412150 6.37 ENSRNOT00000047252
similar to ribosomal protein S24
chr13_-_51784639 6.34 ENSRNOT00000089068
protein phosphatase 1, regulatory subunit 12B
chr10_+_75088422 6.15 ENSRNOT00000081951
myeloperoxidase
chr3_-_16753987 6.00 ENSRNOT00000091257

chr13_+_90260783 5.90 ENSRNOT00000050547
CD84 molecule
chr13_-_83425641 5.70 ENSRNOT00000063870
T-box 19
chr12_-_18303041 5.61 ENSRNOT00000032844
similar to Leukosialin precursor (Leucocyte sialoglycoprotein) (Sialophorin) (CD43) (W3/13 antigen)
chr7_-_15852930 5.54 ENSRNOT00000009270
similar to zinc finger protein 101
chr9_-_53315915 5.53 ENSRNOT00000038093
myostatin
chr1_+_84304228 5.43 ENSRNOT00000024771
periaxin
chr14_-_81023682 5.39 ENSRNOT00000081570
regulator of G-protein signaling 12
chr18_+_47613854 5.29 ENSRNOT00000025270
zinc finger protein 474
chr9_-_121725716 5.26 ENSRNOT00000087405
adenylate cyclase activating polypeptide 1
chr3_+_113918629 5.01 ENSRNOT00000078978
ENSRNOT00000037168
CTD small phosphatase like 2
chr3_+_5709236 4.98 ENSRNOT00000061201
ENSRNOT00000070887
dopamine beta-hydroxylase
chr14_+_91557601 4.95 ENSRNOT00000038733
hypothetical LOC289778
chr3_-_20518105 4.95 ENSRNOT00000050435

chr2_+_242882306 4.95 ENSRNOT00000013661
DNA-damage-inducible transcript 4-like
chr15_+_29208606 4.79 ENSRNOT00000073722
ENSRNOT00000086054
uncharacterized LOC100911980
chr4_-_165118062 4.76 ENSRNOT00000087219
Ly49s8
chr9_-_52238564 4.57 ENSRNOT00000005073
collagen type V alpha 2 chain
chr4_-_176909075 4.56 ENSRNOT00000067489
ATP binding cassette subfamily C member 9
chr13_+_48455923 4.45 ENSRNOT00000009280
Rab7b, member RAS oncogene family
chr7_-_104486710 4.45 ENSRNOT00000084764
gasdermin C
chr1_-_7443863 4.45 ENSRNOT00000088558
phosphatase and actin regulator 2
chr20_-_32296840 4.42 ENSRNOT00000080727
storkhead box 1
chr8_-_128521109 4.42 ENSRNOT00000034025
sodium voltage-gated channel alpha subunit 11
chr4_+_136078391 4.42 ENSRNOT00000048672

chr7_-_122329443 4.40 ENSRNOT00000032232
megakaryoblastic leukemia (translocation) 1
chr9_-_65737538 4.33 ENSRNOT00000014939
trafficking kinesin protein 2
chr17_-_15566332 4.25 ENSRNOT00000093743
extracellular matrix protein 2
chr5_+_147257678 4.20 ENSRNOT00000066268
ring finger protein 19B
chrX_+_77076106 4.19 ENSRNOT00000091527
ENSRNOT00000089381
ATPase copper transporting alpha
chr11_-_54545230 4.17 ENSRNOT00000002676
resistin like alpha
chr2_-_59084059 4.15 ENSRNOT00000086323
ENSRNOT00000088701
sperm flagellar 2
chr9_-_88534710 4.04 ENSRNOT00000020880
transmembrane 4 L six family member 20
chr8_-_58253688 3.93 ENSRNOT00000010956
cullin 5
chr5_-_16995304 3.87 ENSRNOT00000061780
short chain dehydrogenase/reductase family 16C, member 6
chr11_+_85633243 3.84 ENSRNOT00000045807
Ig lambda chain V-VI region AR-like
chr3_-_153321352 3.78 ENSRNOT00000064824
RB transcriptional corepressor like 1
chr15_-_108326907 3.74 ENSRNOT00000016848
G protein-coupled receptor 18
chr1_+_42121636 3.72 ENSRNOT00000025616
myc target 1
chr1_-_197801634 3.70 ENSRNOT00000090200
nuclear factor of activated T-cells 2 interacting protein
chr13_-_84759098 3.70 ENSRNOT00000058683
similar to flavin containing monooxygenase 5
chr10_-_74413745 3.69 ENSRNOT00000038296
proline rich 11
chr20_+_17750744 3.63 ENSRNOT00000000745
similar to RIKEN cDNA 1700049L16
chr20_+_3146856 3.62 ENSRNOT00000050159
RT1 class Ib, locus N2
chr5_-_16995521 3.61 ENSRNOT00000080197
short chain dehydrogenase/reductase family 16C, member 6
chr14_-_45863877 3.60 ENSRNOT00000002977
phosphoglucomutase 2
chr8_-_68275720 3.60 ENSRNOT00000079122
mitogen activated protein kinase kinase 5
chr15_+_31417147 3.59 ENSRNOT00000092182

chr15_-_49467174 3.56 ENSRNOT00000019209
ADAM metallopeptidase domain 7
chr1_-_7322424 3.53 ENSRNOT00000066725
ENSRNOT00000081112
zinc finger, C2HC-type containing 1B
chr8_-_18762922 3.50 ENSRNOT00000008423
olfactory receptor 1122
chr9_+_17734345 3.49 ENSRNOT00000067104
calpain 11
chr15_-_29761117 3.49 ENSRNOT00000075194

chr2_+_4989295 3.32 ENSRNOT00000041541
family with sequence similarity 172, member A
chr2_+_147006830 3.24 ENSRNOT00000080780

chr4_-_170186942 3.20 ENSRNOT00000082235
WW domain-binding protein 11-like 1
chrX_+_26440584 3.20 ENSRNOT00000087293
ENSRNOT00000005328
amelogenin, X-linked
chr19_+_49462129 3.19 ENSRNOT00000015158
centromere protein N
chr12_+_41200718 3.17 ENSRNOT00000038426
ENSRNOT00000048450
ENSRNOT00000067176
2'-5' oligoadenylate synthetase 1A
chr1_+_168378637 3.14 ENSRNOT00000028936
olfactory receptor 86
chr3_-_71798531 3.05 ENSRNOT00000088170
calcitonin receptor like receptor
chr6_-_86223052 3.02 ENSRNOT00000046828
fibrous sheath CABYR binding protein
chr1_-_236900904 3.01 ENSRNOT00000066846

chr14_-_21553949 2.92 ENSRNOT00000031642
submaxillary gland androgen regulated protein 3B
chr1_-_141504111 2.76 ENSRNOT00000040164
small nuclear ribonucleoprotein polypeptide E pseudogene 2
chr1_-_227392054 2.70 ENSRNOT00000054806
membrane-spanning 4-domains, subfamily A, member 13, pseudogene 1
chr1_-_90151405 2.69 ENSRNOT00000028688
similar to RIKEN cDNA 4931406P16
chr13_+_71322759 2.64 ENSRNOT00000071815
transmembrane epididymal protein 1
chr2_-_137153551 2.62 ENSRNOT00000083443

chr3_-_76926151 2.60 ENSRNOT00000049517
olfactory receptor 641
chr14_+_42007312 2.56 ENSRNOT00000063985
ATPase phospholipid transporting 8A1
chrX_+_119390013 2.50 ENSRNOT00000074269
angiotensin II receptor, type 2
chr17_+_39544281 2.39 ENSRNOT00000022871
Prolactin family 2, subfamily b, member 1
chr11_-_43099412 2.27 ENSRNOT00000002281
gamma-aminobutyric acid type A receptor rho3 subunit
chr12_+_38368693 2.24 ENSRNOT00000083261
CAP-GLY domain containing linker protein 1
chr2_-_256154584 2.24 ENSRNOT00000072487

chr13_-_82295123 2.21 ENSRNOT00000090120
similar to hypothetical protein FLJ10706
chr12_+_703281 2.20 ENSRNOT00000001464
ENSRNOT00000064951
ENSRNOT00000050733
PDS5 cohesin associated factor B
chr7_+_74350479 2.17 ENSRNOT00000089034

chr19_+_56803382 2.17 ENSRNOT00000036042
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr2_+_260039651 2.16 ENSRNOT00000073873
ankyrin repeat and SOCS box-containing 17
chrX_-_118513061 2.15 ENSRNOT00000043338
interleukin 13 receptor subunit alpha 2
chr9_+_17784468 2.13 ENSRNOT00000026831
solute carrier family 29 member 1
chr8_-_32431987 2.04 ENSRNOT00000048460
similar to 60S ribosomal protein L32
chr2_-_43067956 2.02 ENSRNOT00000090616
GC-rich promoter binding protein 1
chr16_+_71242470 2.01 ENSRNOT00000030489
leucine zipper and EF-hand containing transmembrane protein 2
chr11_-_23058456 1.99 ENSRNOT00000073285
olfactory receptor 6C6-like
chr5_+_116420690 1.99 ENSRNOT00000087089
nuclear factor I/A
chr6_-_77848434 1.95 ENSRNOT00000034342
solute carrier family 25 member 21
chr3_-_13896838 1.92 ENSRNOT00000025399
F-box and WD repeat domain containing 2
chr8_+_122197027 1.91 ENSRNOT00000013050
upstream binding protein 1 (LBP-1a)
chr7_+_120161091 1.91 ENSRNOT00000013764
nucleolar protein 12
chr13_+_110372164 1.87 ENSRNOT00000049634
similar to ribosomal protein L37
chr13_-_67688477 1.85 ENSRNOT00000068148
proteoglycan 4
chr1_-_246010594 1.80 ENSRNOT00000023762
regulatory factor X3
chr20_+_3167079 1.80 ENSRNOT00000001035
RT1 class Ib, locus N3
chr8_+_36850324 1.79 ENSRNOT00000060448
prostate and testis expressed 2
chr3_+_103597194 1.77 ENSRNOT00000073004
similar to olfactory receptor 1318
chr20_-_29558321 1.72 ENSRNOT00000000702
anaphase promoting complex subunit 16
chr4_+_160020472 1.55 ENSRNOT00000078802
poly (ADP-ribose) polymerase family, member 11
chrX_+_123912361 1.55 ENSRNOT00000092622
reproductive homeobox 5
chr5_-_113880911 1.53 ENSRNOT00000029441
equatorin
chr9_+_44681494 1.52 ENSRNOT00000035785
eukaryotic translation initiation factor 5B
chr7_+_132378273 1.52 ENSRNOT00000010990
hypothetical protein LOC690142
chr9_+_72933304 1.51 ENSRNOT00000041632
crystallin, gamma F
chr14_+_83889089 1.44 ENSRNOT00000078980
MORC family CW-type zinc finger 2
chr2_+_193627243 1.40 ENSRNOT00000082934

chr16_+_68586235 1.39 ENSRNOT00000039592
uncharacterized LOC103693984
chr4_-_58006839 1.37 ENSRNOT00000076645
centrosomal protein 41
chr16_+_51730452 1.34 ENSRNOT00000078614
a disintegrin and metalloprotease domain 34-like
chr9_-_44617210 1.33 ENSRNOT00000074343
lysozyme G1
chr18_+_30904498 1.33 ENSRNOT00000026969
protocadherin gamma subfamily A, 11
chr11_-_29638922 1.30 ENSRNOT00000048888
ribosomal protein L29-like
chr9_-_43454078 1.27 ENSRNOT00000023550
transmembrane protein 131
chrX_-_70938489 1.26 ENSRNOT00000041731
testis expressed 11
chr3_-_74567685 1.23 ENSRNOT00000068048
olfactory receptor 532
chr19_-_11669578 1.20 ENSRNOT00000026373
G protein subunit alpha o1
chrX_+_43745604 1.18 ENSRNOT00000040825
rCG36365-like
chr4_+_113918740 1.15 ENSRNOT00000086359
ladybird homeobox 2
chr15_-_27077160 1.14 ENSRNOT00000016721
olfactory receptor 1611
chr1_+_129255396 1.13 ENSRNOT00000040147
family with sequence similarity 169, member B
chr1_+_164705604 1.11 ENSRNOT00000051450
ENSRNOT00000071384
olfactory receptor 36
chr4_-_177039677 1.10 ENSRNOT00000055538
ENSRNOT00000075667
similar to Hypothetical protein MGC75664
chr19_+_26184545 1.06 ENSRNOT00000005656
deoxyhypusine synthase
chr4_+_114784408 1.06 ENSRNOT00000011189
transcription factor LBX2
chr18_-_32670665 1.05 ENSRNOT00000019409
nuclear receptor subfamily 3, group C, member 1
chr3_-_72808425 1.01 ENSRNOT00000048581
olfactory receptor 441
chr8_+_40707068 1.00 ENSRNOT00000074529
olfactory receptor 1214
chr3_-_57957346 0.99 ENSRNOT00000036728
solute carrier family 25 member 12
chr3_-_78429583 0.97 ENSRNOT00000042658
olfactory receptor 705
chr8_-_18408179 0.96 ENSRNOT00000040032

chrX_+_45614888 0.94 ENSRNOT00000058473
uncharacterized LOC100909677
chr8_+_41358307 0.93 ENSRNOT00000071307
olfactory receptor 143-like
chr20_+_1021594 0.92 ENSRNOT00000071933
olfactory receptor 14J1-like
chr13_-_98023829 0.90 ENSRNOT00000075426
kinesin family member 28, pseudogene
chr9_-_121972055 0.84 ENSRNOT00000089735
clusterin-like protein 1
chr8_-_19386384 0.83 ENSRNOT00000051572
olfactory receptor 1145
chr2_+_115272156 0.83 ENSRNOT00000075059
olfactory receptor 146-like
chr5_-_128839433 0.80 ENSRNOT00000065280
oxysterol binding protein-like 9
chr13_+_73661131 0.79 ENSRNOT00000068548
similar to interferon induced transmembrane protein 2 (1-8D)
chr8_-_4003593 0.77 ENSRNOT00000072660
vomeronasal 2 receptor, 24
chr4_+_71512695 0.77 ENSRNOT00000037220
taste receptor, type 2, member 139
chr3_+_75809445 0.76 ENSRNOT00000049950
olfactory receptor 581
chr7_+_58570579 0.74 ENSRNOT00000081227
RIKEN cDNA A930009A15 gene
chr3_-_176197753 0.73 ENSRNOT00000013189
death inducer-obliterator 1
chrX_-_97262013 0.68 ENSRNOT00000040168
claudin 34C4
chr8_+_40345160 0.67 ENSRNOT00000076308
olfactory receptor 1200
chr1_+_148862493 0.65 ENSRNOT00000073451
olfactory receptor 10A5-like
chr1_+_266844480 0.64 ENSRNOT00000027482
TATA-box binding protein associated factor 5
chr3_-_78663607 0.63 ENSRNOT00000073134
olfactory receptor 718

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxa10

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
8.7 52.4 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
8.1 40.4 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
4.3 17.0 GO:0002337 B-1a B cell differentiation(GO:0002337)
3.8 11.4 GO:0021698 cerebellar cortex structural organization(GO:0021698)
3.6 10.9 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
2.8 8.4 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
2.2 13.4 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
2.0 6.1 GO:0002148 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
2.0 12.2 GO:0014866 skeletal myofibril assembly(GO:0014866)
1.8 12.7 GO:0002370 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
1.8 5.4 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
1.7 24.0 GO:0006968 cellular defense response(GO:0006968)
1.7 5.0 GO:0046333 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
1.5 4.5 GO:0034499 late endosome to Golgi transport(GO:0034499)
1.5 5.9 GO:0032701 negative regulation of interleukin-18 production(GO:0032701)
1.3 8.1 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
1.3 5.3 GO:0002877 regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
1.3 6.5 GO:0006177 GMP biosynthetic process(GO:0006177)
1.3 9.0 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
1.2 3.6 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
1.1 4.6 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
1.0 4.2 GO:0034760 negative regulation of iron ion transmembrane transport(GO:0034760) elastin biosynthetic process(GO:0051542) regulation of cytochrome-c oxidase activity(GO:1904959)
1.0 6.7 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.9 4.6 GO:0060327 cytoplasmic actin-based contraction involved in cell motility(GO:0060327)
0.9 13.5 GO:0015671 oxygen transport(GO:0015671)
0.9 5.4 GO:0023021 termination of signal transduction(GO:0023021)
0.9 2.6 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.8 2.5 GO:0035566 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) regulation of metanephros size(GO:0035566)
0.8 5.5 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816) negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.7 2.1 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.7 15.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.6 4.4 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.6 1.8 GO:2000078 glandular epithelial cell maturation(GO:0002071) positive regulation of type B pancreatic cell development(GO:2000078)
0.6 21.9 GO:0006730 one-carbon metabolic process(GO:0006730)
0.5 4.4 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.5 18.8 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.4 2.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.4 3.9 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.3 1.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.3 1.9 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.3 1.5 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.3 4.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.3 2.1 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.3 3.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.3 1.1 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.3 1.3 GO:0035822 meiotic gene conversion(GO:0006311) gene conversion(GO:0035822)
0.2 1.0 GO:0070778 malate-aspartate shuttle(GO:0043490) L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.2 3.0 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.2 4.2 GO:0072643 interferon-gamma secretion(GO:0072643)
0.2 9.9 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.2 1.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.2 3.2 GO:0070166 enamel mineralization(GO:0070166)
0.2 3.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.2 1.1 GO:0006598 polyamine catabolic process(GO:0006598)
0.1 2.0 GO:0072189 ureter development(GO:0072189)
0.1 11.2 GO:0030101 natural killer cell activation(GO:0030101)
0.1 8.6 GO:0045576 mast cell activation(GO:0045576)
0.1 3.2 GO:0034508 centromere complex assembly(GO:0034508)
0.1 5.4 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 7.3 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.1 0.5 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 5.7 GO:0021983 pituitary gland development(GO:0021983)
0.1 13.7 GO:0021987 cerebral cortex development(GO:0021987)
0.1 3.7 GO:0016925 protein sumoylation(GO:0016925)
0.1 2.2 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 0.5 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 1.4 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.1 0.3 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 2.1 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.4 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 4.2 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 3.7 GO:0007050 cell cycle arrest(GO:0007050)
0.0 3.6 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 4.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.5 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.8 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 1.2 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.5 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.6 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.3 GO:0050912 detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.0 1.5 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 1.5 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 3.2 GO:0051607 defense response to virus(GO:0051607)
0.0 0.6 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.9 GO:0072384 organelle transport along microtubule(GO:0072384)
0.0 0.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 13.4 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
2.2 6.7 GO:0070557 PCNA-p21 complex(GO:0070557)
1.2 5.0 GO:0034774 secretory granule lumen(GO:0034774)
1.2 13.5 GO:0005833 hemoglobin complex(GO:0005833)
1.1 4.6 GO:0005588 collagen type V trimer(GO:0005588)
1.1 4.6 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
1.1 4.4 GO:0044299 C-fiber(GO:0044299)
0.7 8.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.6 56.6 GO:0031526 brush border membrane(GO:0031526)
0.5 4.2 GO:0044194 cytolytic granule(GO:0044194)
0.5 3.9 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.4 6.1 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.4 1.5 GO:0002079 inner acrosomal membrane(GO:0002079)
0.4 4.1 GO:0002177 manchette(GO:0002177)
0.3 11.4 GO:0051233 spindle midzone(GO:0051233)
0.3 12.2 GO:0008180 COP9 signalosome(GO:0008180)
0.2 2.2 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.2 7.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 4.2 GO:0005614 interstitial matrix(GO:0005614)
0.2 3.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 41.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 6.3 GO:0031672 A band(GO:0031672)
0.1 2.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 1.3 GO:0000801 central element(GO:0000801)
0.1 10.1 GO:0005884 actin filament(GO:0005884)
0.1 0.5 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 1.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.6 GO:0061700 GATOR2 complex(GO:0061700)
0.1 4.5 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 0.5 GO:0005827 polar microtubule(GO:0005827)
0.1 4.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 19.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 3.0 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 2.2 GO:0016235 aggresome(GO:0016235)
0.0 1.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 13.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 19.0 GO:0005929 cilium(GO:0005929)
0.0 3.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.5 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.4 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.5 GO:0002102 podosome(GO:0002102)
0.0 3.7 GO:0005938 cell cortex(GO:0005938)
0.0 3.2 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
10.5 52.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
4.3 17.0 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
3.4 13.4 GO:0019002 GMP binding(GO:0019002)
2.2 9.0 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
2.2 6.7 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
1.7 21.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
1.7 5.0 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
1.5 4.6 GO:0008281 sulfonylurea receptor activity(GO:0008281)
1.4 8.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
1.3 18.8 GO:0017154 semaphorin receptor activity(GO:0017154)
1.0 3.0 GO:0001605 adrenomedullin receptor activity(GO:0001605)
0.9 13.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.9 13.7 GO:0051400 BH domain binding(GO:0051400)
0.8 4.2 GO:0070052 collagen V binding(GO:0070052)
0.8 4.2 GO:0032767 copper-exporting ATPase activity(GO:0004008) copper-dependent protein binding(GO:0032767) copper-transporting ATPase activity(GO:0043682)
0.8 3.2 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.7 3.6 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.7 11.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.7 12.2 GO:0005523 tropomyosin binding(GO:0005523)
0.5 2.5 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.5 3.7 GO:0031386 protein tag(GO:0031386)
0.4 15.6 GO:0008009 chemokine activity(GO:0008009) CCR chemokine receptor binding(GO:0048020)
0.4 3.9 GO:0005000 vasopressin receptor activity(GO:0005000)
0.4 3.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.4 8.1 GO:0002162 dystroglycan binding(GO:0002162)
0.3 3.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3 3.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.3 4.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.3 6.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.2 4.1 GO:0050811 GABA receptor binding(GO:0050811)
0.2 32.4 GO:0005179 hormone activity(GO:0005179)
0.2 1.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.2 4.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 2.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 0.5 GO:0031208 POZ domain binding(GO:0031208)
0.1 4.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 6.1 GO:0004601 peroxidase activity(GO:0004601)
0.1 14.0 GO:0003823 antigen binding(GO:0003823)
0.1 3.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 5.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 20.6 GO:0005057 receptor signaling protein activity(GO:0005057)
0.1 2.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 5.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 3.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.1 GO:1990239 steroid hormone binding(GO:1990239)
0.1 4.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 1.3 GO:0003796 lysozyme activity(GO:0003796)
0.1 1.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.4 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 1.9 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 4.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 10.5 GO:0017124 SH3 domain binding(GO:0017124)
0.1 1.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 1.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 0.8 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 15.0 GO:0030246 carbohydrate binding(GO:0030246)
0.0 5.7 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 6.5 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0 0.3 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 2.0 GO:0043022 ribosome binding(GO:0043022)
0.0 1.9 GO:0019843 rRNA binding(GO:0019843)
0.0 16.5 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0 0.4 GO:0043422 protein kinase B binding(GO:0043422)
0.0 1.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0008527 taste receptor activity(GO:0008527)
0.0 1.1 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.5 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.1 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.6 GO:0004402 histone acetyltransferase activity(GO:0004402)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 41.1 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.7 6.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.3 2.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.2 10.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.2 10.3 PID BCR 5PATHWAY BCR signaling pathway
0.2 6.1 PID IL23 PATHWAY IL23-mediated signaling events
0.2 3.6 ST GA12 PATHWAY G alpha 12 Pathway
0.1 11.1 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 1.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 4.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 30.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 4.4 PID RHOA PATHWAY RhoA signaling pathway
0.1 2.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 2.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 4.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 0.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 7.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 3.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 0.4 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 3.9 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.7 36.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.7 49.1 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.5 6.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.4 6.7 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.4 22.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.4 19.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.3 9.6 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.3 12.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.3 15.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.3 5.0 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.2 5.3 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.2 4.6 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.2 3.8 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 4.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 8.6 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 11.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 1.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 3.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 2.1 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 3.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.1 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.6 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 3.6 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 1.0 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 2.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 2.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.0 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis