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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Hnf4g

Z-value: 2.70

Motif logo

Transcription factors associated with Hnf4g

Gene Symbol Gene ID Gene Info
ENSRNOG00000008971 hepatocyte nuclear factor 4, gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hnf4grn6_v1_chr2_-_100372252_1003722520.683.5e-45Click!

Activity profile of Hnf4g motif

Sorted Z-values of Hnf4g motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_123621102 134.30 ENSRNOT00000046024
cytochrome P450, family 2, subfamily d, polypeptide 5
chr16_-_81834945 107.28 ENSRNOT00000037806
coagulation factor VII
chr7_-_123655896 101.23 ENSRNOT00000012413
cytochrome P450, family 2, subfamily d, polypeptide 2
chr1_+_21525421 99.12 ENSRNOT00000017911
arginase 1
chr18_-_35071619 94.97 ENSRNOT00000075695
serine protease inhibitor Kazal-type 3-like
chr11_-_81660395 94.54 ENSRNOT00000048739
fetuin B
chr4_-_30338679 93.70 ENSRNOT00000012050
paraoxonase 3
chr2_-_23256158 89.88 ENSRNOT00000015336
betaine-homocysteine S-methyltransferase
chr11_+_65022100 88.05 ENSRNOT00000003934
nuclear receptor subfamily 1, group I, member 2
chr9_+_16314173 87.20 ENSRNOT00000072812
glycine N-methyltransferase-like
chr7_-_123630045 86.05 ENSRNOT00000050002
cytochrome P450, family 2, subfamily d, polypeptide 1
chr4_+_154215250 85.23 ENSRNOT00000072465
murinoglobulin 2
chr1_+_100470722 85.05 ENSRNOT00000086917
aspartate dehydrogenase domain containing
chr10_+_56662242 84.64 ENSRNOT00000086919
asialoglycoprotein receptor 1
chr11_-_81444375 83.41 ENSRNOT00000058479
ENSRNOT00000078131
ENSRNOT00000080949
ENSRNOT00000080562
ENSRNOT00000084867
kininogen 1
chr1_+_213511874 83.28 ENSRNOT00000078080
ENSRNOT00000016883
cytochrome P450, family 2, subfamily e, polypeptide 1
chr2_-_23289266 78.42 ENSRNOT00000061708
betaine-homocysteine S-methyltransferase 2
chr7_-_123638702 75.49 ENSRNOT00000082473
ENSRNOT00000044470
ENSRNOT00000092017
cytochrome P450, family 2, subfamily d, polypeptide 1
chr1_+_193424812 75.01 ENSRNOT00000019939
aquaporin 8
chr17_+_9736786 74.56 ENSRNOT00000081920
coagulation factor XII
chr2_+_20857202 74.52 ENSRNOT00000078919
acyl-CoA thioesterase 12
chr19_+_50246402 74.41 ENSRNOT00000018795
hydroxysteroid (17-beta) dehydrogenase 2
chr10_+_56662561 74.24 ENSRNOT00000025254
asialoglycoprotein receptor 1
chr7_-_117679219 73.52 ENSRNOT00000071522
solute carrier family 39 member 4
chr9_-_4168221 72.36 ENSRNOT00000061861
sulfotransferase family, cytosolic, 1C, member 2a
chr3_+_171213936 70.58 ENSRNOT00000031586
phosphoenolpyruvate carboxykinase 1
chr5_+_160306727 69.61 ENSRNOT00000016648
agmatinase
chr13_+_89597138 69.31 ENSRNOT00000004662
apolipoprotein A2
chr1_-_76722965 68.98 ENSRNOT00000052129
alcohol sulfotransferase-like
chr4_+_99063181 67.74 ENSRNOT00000008840
fatty acid binding protein 1
chr5_-_134207847 67.24 ENSRNOT00000083686
ENSRNOT00000088209
ENSRNOT00000051252
cytochrome P450, family 4, subfamily a, polypeptide 2
chr1_-_76780230 66.96 ENSRNOT00000002046
alcohol sulfotransferase-like
chr1_+_282678166 65.03 ENSRNOT00000045656
carboxylesterase 2C
chr8_-_130550388 63.19 ENSRNOT00000026355
cytochrome P450, family 8, subfamily b, polypeptide 1
chr6_-_129010271 62.08 ENSRNOT00000075378
serpin family A member 10
chr11_-_66034573 62.07 ENSRNOT00000003645
homogentisate 1, 2-dioxygenase
chr1_-_263803150 61.73 ENSRNOT00000017840
cytochrome P450, family 2, subfamily c, polypeptide 23
chr9_+_95285592 60.99 ENSRNOT00000063853
UDP glucuronosyltransferase family 1 member A5
chr5_+_60528997 60.88 ENSRNOT00000051445
glyoxylate and hydroxypyruvate reductase
chr1_-_224533219 59.17 ENSRNOT00000051289
integral membrane transport protein UST5r
chr1_-_80594136 58.51 ENSRNOT00000024800
apolipoprotein C2
chr5_-_124403195 58.34 ENSRNOT00000067850
complement C8 alpha chain
chr3_-_127500709 58.22 ENSRNOT00000006330
hydroxyacid oxidase 1
chr12_-_48365784 57.51 ENSRNOT00000077317
D-amino-acid oxidase
chr15_+_18451144 56.31 ENSRNOT00000010260
acyl-CoA oxidase 2
chr10_+_65767053 56.24 ENSRNOT00000078897
vitronectin
chr7_-_117680004 55.54 ENSRNOT00000040422
solute carrier family 39 member 4
chr16_+_18736154 55.42 ENSRNOT00000015723
mannose-binding lectin (protein A) 1
chr8_+_50525091 55.40 ENSRNOT00000074357
apolipoprotein A1
chr1_+_20856187 55.15 ENSRNOT00000071726
small leucine-rich protein 1
chr1_+_282640706 54.96 ENSRNOT00000073241
ENSRNOT00000080995
carboxylesterase 2C
chr17_-_43543172 54.58 ENSRNOT00000080684
ENSRNOT00000029626
ENSRNOT00000082719
solute carrier family 17 member 3
chrX_+_143097525 53.42 ENSRNOT00000004559
coagulation factor IX
chr2_+_150146234 53.01 ENSRNOT00000018761
arylacetamide deacetylase
chr9_-_4945352 52.92 ENSRNOT00000082530
sulfotransferase family 1C member 3
chr7_+_140781799 52.13 ENSRNOT00000087932
DnaJ heat shock protein family (Hsp40) member C22
chr14_-_86164341 51.83 ENSRNOT00000086343
ENSRNOT00000080147
glucokinase
chr1_+_219233750 51.64 ENSRNOT00000024112
aminoacylase 3
chr16_-_32868680 50.83 ENSRNOT00000015974
ENSRNOT00000082392
aminoadipate aminotransferase
chr19_+_15339152 50.78 ENSRNOT00000060929
carboxylesterase 1A
chr12_-_11733099 50.64 ENSRNOT00000051244
ENSRNOT00000087257
cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1
chr9_+_95256627 50.54 ENSRNOT00000025291
UDP glucuronosyltransferase family 1 member A5
chr9_+_95274707 50.36 ENSRNOT00000045163
UDP glucuronosyltransferase family 1 member A5
chr4_-_115332052 50.09 ENSRNOT00000017643
C-type lectin domain family 4, member F
chr2_+_188449210 49.58 ENSRNOT00000027700
pyruvate kinase, liver and RBC
chr1_+_100471066 49.27 ENSRNOT00000067562
aspartate dehydrogenase domain containing
chr9_+_95295701 49.14 ENSRNOT00000025045
UDP glucuronosyltransferase family 1 member A5
chr16_+_20521956 48.53 ENSRNOT00000026597
pyroglutamyl-peptidase I
chr5_+_137357674 48.48 ENSRNOT00000092813
similar to RIKEN cDNA 2610528J11
chr2_+_181987217 48.03 ENSRNOT00000034521
fibrinogen gamma chain
chr8_+_117117430 47.85 ENSRNOT00000073247
glutathione peroxidase 1
chrX_+_134940615 47.36 ENSRNOT00000005604
X-prolyl aminopeptidase 2
chr9_+_95501778 47.06 ENSRNOT00000086805
secreted phosphoprotein 2
chr10_+_71159869 46.66 ENSRNOT00000075977
ENSRNOT00000047427
HNF1 homeobox B
chr3_-_150603082 46.65 ENSRNOT00000024310
adenosylhomocysteinase
chr2_-_235052464 46.63 ENSRNOT00000093512
uncharacterized LOC103691699
chr13_+_91080341 46.34 ENSRNOT00000000058
C-reactive protein
chr20_-_12820466 46.25 ENSRNOT00000001699
formimidoyltransferase cyclodeaminase
chr1_-_102013243 46.24 ENSRNOT00000042115
ATP binding cassette subfamily C member 6
chr11_-_81717521 46.02 ENSRNOT00000058422
alpha-2-HS-glycoprotein
chr6_+_127946686 45.86 ENSRNOT00000082680
Ab1-233
chr1_+_251145253 45.79 ENSRNOT00000083555
ENSRNOT00000014979
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr15_+_34155504 45.73 ENSRNOT00000024782
dehydrogenase/reductase 4
chr13_-_50499060 45.73 ENSRNOT00000065347
ENSRNOT00000076924
ethanolamine kinase 2
chr6_-_127620296 45.67 ENSRNOT00000012577
serpin family A member 1
chr12_+_47407811 45.66 ENSRNOT00000001565
HNF1 homeobox A
chr18_+_59830363 45.45 ENSRNOT00000082650
ENSRNOT00000078378
one cut domain, family member 2
chr16_+_6970342 45.14 ENSRNOT00000061294
ENSRNOT00000048344
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr4_-_30276372 45.13 ENSRNOT00000011823
paraoxonase 1
chr1_+_16910069 44.59 ENSRNOT00000020015
aldehyde dehydrogenase 8 family, member A1
chr17_-_32076181 44.44 ENSRNOT00000074842
leukocyte elastase inhibitor A-like
chr1_-_224389389 44.37 ENSRNOT00000077408
ENSRNOT00000050010
integral membrane transport protein UST4r
chr2_+_60337667 44.13 ENSRNOT00000024035
alanine-glyoxylate aminotransferase 2
chr14_+_87448692 43.95 ENSRNOT00000077177
insulin-like growth factor binding protein 1
chr3_-_10371240 43.84 ENSRNOT00000012075
argininosuccinate synthase 1
chr1_-_76614279 43.53 ENSRNOT00000041367
ENSRNOT00000089371
alcohol sulfotransferase-like
chr2_+_55775274 43.07 ENSRNOT00000018545
complement C9
chr1_+_83744238 42.75 ENSRNOT00000028249
cytochrome P450, family 2, subfamily a, polypeptide 1
chr16_+_74534130 42.61 ENSRNOT00000050637
solute carrier family 25 member 15
chr1_-_258766881 42.26 ENSRNOT00000015801
cytochrome P450, family 2, subfamily c, polypeptide 12
chr20_-_4542073 42.18 ENSRNOT00000000477
complement factor B
chr17_+_30617382 42.04 ENSRNOT00000048923
enoyl-CoA delta isomerase 2
chr5_+_157801163 41.96 ENSRNOT00000024160
aldo-keto reductase family 7 member A3
chr7_+_70980422 41.37 ENSRNOT00000077912
retinol dehydrogenase 16 (all-trans)
chr7_+_71065197 41.31 ENSRNOT00000051075
retinol dehydrogenase 16 (all-trans)
chr3_-_101465995 40.90 ENSRNOT00000080175
gamma-butyrobetaine hydroxylase 1
chr5_-_78985990 40.87 ENSRNOT00000009248
alpha-1-microglobulin/bikunin precursor
chr2_+_23289374 40.50 ENSRNOT00000090666
ENSRNOT00000032783
dimethylglycine dehydrogenase
chr4_-_176679815 40.49 ENSRNOT00000090122
glycogen synthase 2
chr7_-_2677199 40.34 ENSRNOT00000043908
apolipoprotein N
chr1_+_83103925 40.28 ENSRNOT00000047540
ENSRNOT00000028196
cytochrome P450, family 2, subfamily b, polypeptide 2
chr1_-_224698514 40.26 ENSRNOT00000024234
solute carrier family 22, member 25
chr18_-_28428117 40.10 ENSRNOT00000078202
solute carrier family 23 member 1
chr1_-_219311502 40.06 ENSRNOT00000085439
similar to hypothetical protein MGC37914
chr9_+_9721105 39.68 ENSRNOT00000073042
ENSRNOT00000075494
complement C3
chr5_+_79179417 39.62 ENSRNOT00000010454
orosomucoid 1
chr9_-_15582556 39.48 ENSRNOT00000020516
similar to AI661453 protein
chr7_-_3386522 39.45 ENSRNOT00000010760
methyltransferase like 7B
chr6_-_127508452 39.35 ENSRNOT00000073709
protein Z-dependent protease inhibitor-like
chr4_+_157126935 39.24 ENSRNOT00000056051
complement C1r
chrX_-_1848904 39.17 ENSRNOT00000010984
regucalcin
chr1_+_81456984 38.94 ENSRNOT00000027075
ETHE1, persulfide dioxygenase
chr2_+_211546560 38.79 ENSRNOT00000033443
AKNA domain containing 1
chr4_-_82702429 38.53 ENSRNOT00000011069
3-hydroxyisobutyrate dehydrogenase
chr10_+_109708755 38.51 ENSRNOT00000083601
glucagon receptor
chr6_+_128050250 38.41 ENSRNOT00000077517
ENSRNOT00000013961
Ab1-233
chr1_-_259287684 38.32 ENSRNOT00000054724
cytochrome P450, family 2, subfamily c, polypeptide 22
chr17_-_69827112 38.29 ENSRNOT00000023835
aldo-keto reductase family 1, member C14
chr1_+_48273611 38.27 ENSRNOT00000022254
ENSRNOT00000022068
solute carrier family 22 member 1
chr15_-_34444244 37.66 ENSRNOT00000027612
cell death-inducing DFFA-like effector b
chr1_+_147713892 37.57 ENSRNOT00000092985
ENSRNOT00000054742
ENSRNOT00000074103
cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1
chr6_-_104631355 37.53 ENSRNOT00000007825
solute carrier family 10 member 1
chr1_+_36320461 37.52 ENSRNOT00000023659
steroid 5 alpha-reductase 1
chr13_-_47397890 37.31 ENSRNOT00000005505
complement component 4 binding protein, beta
chr13_+_99335020 37.27 ENSRNOT00000029787

chr17_-_9762813 36.64 ENSRNOT00000033749
solute carrier family 34 member 1
chr9_+_16565225 36.62 ENSRNOT00000022307
glycine N-methyltransferase
chrX_+_111122552 36.60 ENSRNOT00000083566
ENSRNOT00000085078
ENSRNOT00000090928
claudin 2
chr11_+_61609370 36.47 ENSRNOT00000088880
ENSRNOT00000082533
GRAM domain containing 1C
chr7_+_99158119 36.32 ENSRNOT00000044127
cytochrome P450 2B1
chr1_+_40086470 36.31 ENSRNOT00000021895
iodotyrosine deiodinase
chr13_+_82479998 36.21 ENSRNOT00000079872
coagulation factor V
chr1_-_101596822 35.86 ENSRNOT00000028490
fibroblast growth factor 21
chr18_-_28425944 35.62 ENSRNOT00000084372
solute carrier family 23 member 1
chr3_-_4055806 35.61 ENSRNOT00000026408
1-acylglycerol-3-phosphate O-acyltransferase 2
chr13_+_93684437 35.43 ENSRNOT00000005005
kynurenine 3-monooxygenase
chr14_+_22806132 35.40 ENSRNOT00000002728
UDP glucuronosyltransferase 2 family, polypeptide B10
chr13_-_56763981 35.38 ENSRNOT00000087916
complement factor H-related protein B
chr19_+_42097995 35.33 ENSRNOT00000020197
haptoglobin
chr8_-_27852996 35.22 ENSRNOT00000037790
galactosidase, beta 1-like 2
chr2_+_53109684 35.16 ENSRNOT00000086590
selenoprotein P
chr1_-_221917901 34.95 ENSRNOT00000092270
solute carrier family 22 member 12
chr13_+_44424689 34.86 ENSRNOT00000005206
aminocarboxymuconate semialdehyde decarboxylase
chr14_+_7113544 34.56 ENSRNOT00000038188
hydroxysteroid (17-beta) dehydrogenase 13
chr3_-_5802129 34.48 ENSRNOT00000009555
sarcosine dehydrogenase
chr1_+_83163079 34.41 ENSRNOT00000077725
ENSRNOT00000034845
cytochrome P450, family 2, subfamily b, polypeptide 3
chr5_-_78285451 34.33 ENSRNOT00000019924
ring finger protein 183
chr1_-_76517134 34.27 ENSRNOT00000064593
ENSRNOT00000085775
alcohol sulfotransferase-like
chr13_+_75175254 34.17 ENSRNOT00000044008
SEC16 homolog B, endoplasmic reticulum export factor
chr19_+_15294248 34.10 ENSRNOT00000024622
carboxylesterase 1F
chr12_+_9446940 34.08 ENSRNOT00000074791
ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase
chr9_+_15582564 33.96 ENSRNOT00000020640
uncharacterized LOC100912849
chr16_-_81822716 33.90 ENSRNOT00000026677
coagulation factor X
chr14_+_99919485 33.54 ENSRNOT00000006087
epidermal growth factor receptor
chr6_+_33176778 33.46 ENSRNOT00000046811
ENSRNOT00000007371
apolipoprotein B
chr8_-_111777602 33.19 ENSRNOT00000052317
ENSRNOT00000083855
similar to RIKEN cDNA 1300017J02
chr17_-_8607494 33.02 ENSRNOT00000016138
solute carrier family 25, member 48
chr1_-_198559568 32.91 ENSRNOT00000023080
quinolinate phosphoribosyltransferase
chr1_-_146289465 32.82 ENSRNOT00000017362
abhydrolase domain containing 17C
chr12_-_21832813 32.79 ENSRNOT00000075280
claudin 3
chr15_-_42693694 32.62 ENSRNOT00000022702
gulonolactone (L-) oxidase
chr10_+_56710965 32.55 ENSRNOT00000087121
asialoglycoprotein receptor 2
chr7_+_14891001 32.36 ENSRNOT00000041034
cytochrome P450, family 4, subfamily f, polypeptide 4
chr15_-_3650819 32.30 ENSRNOT00000014273
plasminogen activator, urokinase
chr14_+_17195014 32.24 ENSRNOT00000031667
C-X-C motif chemokine ligand 11
chr9_-_4978892 32.09 ENSRNOT00000015189
sulfotransferase family 1C member 3
chr18_-_15225427 31.96 ENSRNOT00000090853
ring finger protein 125
chr16_-_21099878 31.88 ENSRNOT00000027800
transmembrane 6 superfamily member 2
chr9_-_26707571 31.60 ENSRNOT00000080948

chr10_+_50928309 31.58 ENSRNOT00000033737
heparan sulfate-glucosamine 3-sulfotransferase 3A1
chr14_+_77079402 31.55 ENSRNOT00000042200
solute carrier family 2 member 9
chr10_-_70802782 31.28 ENSRNOT00000045867
chemokine (C-C motif) ligand 6
chr13_-_99287887 31.21 ENSRNOT00000004780
epoxide hydrolase 1
chr13_-_37287458 31.03 ENSRNOT00000003391
insulin induced gene 2
chr13_+_78812394 30.88 ENSRNOT00000076043
serpin family C member 1
chr17_+_69588085 30.55 ENSRNOT00000064884
aldo-keto reductase family 1, member C12-like 1
chr2_+_182006242 30.55 ENSRNOT00000064091
fibrinogen alpha chain
chrX_+_15669191 30.55 ENSRNOT00000013553
MAGI family member, X-linked
chr8_+_71914867 30.49 ENSRNOT00000023372
death-associated protein kinase 2
chr7_-_119689938 30.35 ENSRNOT00000000200
transmembrane protease, serine 6
chr4_-_122237754 30.34 ENSRNOT00000029915
carbohydrate sulfotransferase 13
chr19_-_64303 30.10 ENSRNOT00000015451
carboxylesterase 2A
chr8_-_22937909 29.85 ENSRNOT00000015684
transmembrane protein 205
chr13_+_97702097 29.83 ENSRNOT00000057787
saccharopine dehydrogenase-like oxidoreductase
chr10_+_86399827 29.80 ENSRNOT00000009299
growth factor receptor bound protein 7
chr1_-_199377035 29.70 ENSRNOT00000026572
protease, serine, 8
chr2_+_93669765 29.64 ENSRNOT00000045438
solute carrier family 10, member 5
chr20_-_28263037 29.45 ENSRNOT00000030348
ectodysplasin-A receptor
chr3_-_5976244 29.45 ENSRNOT00000009893
vav guanine nucleotide exchange factor 2
chr1_-_261986759 29.37 ENSRNOT00000021257
pyridine nucleotide-disulphide oxidoreductase domain 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Hnf4g

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
44.8 134.3 GO:0006742 NADP catabolic process(GO:0006742)
43.5 130.4 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
43.0 129.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
41.6 83.3 GO:0016098 monoterpenoid metabolic process(GO:0016098)
41.6 124.7 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
36.8 110.4 GO:1904612 response to 2,3,7,8-tetrachlorodibenzodioxine(GO:1904612)
34.0 102.1 GO:0002254 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353) activation of plasma proteins involved in acute inflammatory response(GO:0002541)
29.1 116.2 GO:0006562 proline catabolic process(GO:0006562)
28.3 113.2 GO:0035565 regulation of pronephros size(GO:0035565)
26.8 321.6 GO:0042738 exogenous drug catabolic process(GO:0042738)
26.4 158.4 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
25.2 75.7 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
24.4 73.2 GO:0019265 glycine biosynthetic process, by transamination of glyoxylate(GO:0019265)
23.4 211.0 GO:0052697 xenobiotic glucuronidation(GO:0052697)
22.8 68.5 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) formamide metabolic process(GO:0043606)
22.6 67.7 GO:0051977 lysophospholipid transport(GO:0051977)
22.3 111.6 GO:1904640 response to methionine(GO:1904640)
21.4 171.4 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
20.3 81.0 GO:0006554 lysine catabolic process(GO:0006554) L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
19.8 99.1 GO:1902023 regulation of amino acid import(GO:0010958) L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
19.5 58.5 GO:0010915 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
19.4 77.7 GO:0048252 lauric acid metabolic process(GO:0048252)
19.4 174.2 GO:0015747 urate transport(GO:0015747)
18.8 75.1 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
18.8 56.3 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
18.7 37.3 GO:0045959 negative regulation of complement activation, classical pathway(GO:0045959)
18.6 92.9 GO:0000066 mitochondrial ornithine transport(GO:0000066)
17.3 51.8 GO:0042732 D-xylose metabolic process(GO:0042732)
17.2 103.2 GO:0046874 quinolinate metabolic process(GO:0046874)
15.9 47.8 GO:0009609 response to symbiotic bacterium(GO:0009609)
15.5 46.6 GO:0097187 dentinogenesis(GO:0097187)
15.2 45.7 GO:0033986 response to methanol(GO:0033986)
15.0 45.1 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
14.8 14.8 GO:0009436 glyoxylate catabolic process(GO:0009436)
14.6 43.8 GO:0000053 argininosuccinate metabolic process(GO:0000053)
14.6 58.2 GO:0009441 glycolate metabolic process(GO:0009441)
14.0 42.0 GO:1901377 toxin catabolic process(GO:0009407) mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) secondary metabolite catabolic process(GO:0090487) organic heteropentacyclic compound catabolic process(GO:1901377)
13.9 69.6 GO:0008295 spermidine biosynthetic process(GO:0008295)
13.7 41.0 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
13.5 94.7 GO:0071267 amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
13.5 148.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
13.2 105.3 GO:1902222 L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
13.1 52.2 GO:0070813 hydrogen sulfide metabolic process(GO:0070813)
12.9 38.7 GO:1903173 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
12.8 38.5 GO:0006574 valine catabolic process(GO:0006574)
12.5 37.6 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
12.5 74.9 GO:0045329 carnitine biosynthetic process(GO:0045329)
12.1 145.7 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
11.6 186.3 GO:0001887 selenium compound metabolic process(GO:0001887)
10.9 250.8 GO:0019373 epoxygenase P450 pathway(GO:0019373)
10.8 32.3 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
10.7 75.0 GO:0015722 canalicular bile acid transport(GO:0015722)
10.6 53.0 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
10.4 51.8 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
9.9 29.8 GO:2000422 regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
9.6 28.8 GO:0046865 isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
9.6 9.6 GO:0070638 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
8.8 26.5 GO:0042412 taurine biosynthetic process(GO:0042412)
8.7 26.1 GO:0015680 intracellular copper ion transport(GO:0015680)
8.6 25.8 GO:0055129 L-proline biosynthetic process(GO:0055129)
8.6 68.9 GO:0033590 response to cobalamin(GO:0033590)
8.5 25.6 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
8.4 75.9 GO:0006703 estrogen biosynthetic process(GO:0006703)
8.3 116.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
8.3 257.4 GO:0019369 arachidonic acid metabolic process(GO:0019369)
8.0 40.2 GO:0015793 glycerol transport(GO:0015793)
7.6 75.8 GO:0070989 oxidative demethylation(GO:0070989)
7.5 52.4 GO:0006534 cysteine metabolic process(GO:0006534)
7.4 7.4 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
7.3 14.5 GO:0003285 septum secundum development(GO:0003285)
7.0 56.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
7.0 20.9 GO:1903116 gastrin-induced gastric acid secretion(GO:0001698) positive regulation of actin filament-based movement(GO:1903116)
6.9 34.5 GO:0006545 glycine biosynthetic process(GO:0006545)
6.9 20.6 GO:0031448 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
6.8 27.3 GO:0015879 carnitine transport(GO:0015879)
6.6 26.2 GO:0072021 ascending thin limb development(GO:0072021) metanephric ascending thin limb development(GO:0072218)
6.5 52.3 GO:0009437 carnitine metabolic process(GO:0009437)
6.5 13.0 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
6.5 38.9 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
6.4 38.3 GO:0015697 quaternary ammonium group transport(GO:0015697)
6.3 12.6 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
6.3 25.1 GO:0051958 methotrexate transport(GO:0051958)
6.2 12.3 GO:0046416 D-amino acid metabolic process(GO:0046416)
6.1 18.3 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
6.0 24.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
6.0 12.1 GO:0039019 pronephric nephron development(GO:0039019)
6.0 48.2 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
6.0 24.0 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
6.0 95.3 GO:1902572 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
5.9 17.8 GO:0018916 nitrobenzene metabolic process(GO:0018916)
5.9 17.7 GO:1990869 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
5.8 17.5 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
5.8 23.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
5.7 28.6 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
5.7 34.2 GO:0060267 positive regulation of respiratory burst(GO:0060267)
5.7 22.8 GO:0033231 carbohydrate export(GO:0033231) daunorubicin transport(GO:0043215) response to borneol(GO:1905230) cellular response to borneol(GO:1905231) response to codeine(GO:1905233) response to quercetin(GO:1905235) drug transport across blood-brain barrier(GO:1990962) establishment of blood-retinal barrier(GO:1990963)
5.7 11.4 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
5.7 62.5 GO:0051132 NK T cell activation(GO:0051132)
5.7 39.6 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
5.6 16.9 GO:0009216 purine deoxyribonucleoside triphosphate biosynthetic process(GO:0009216)
5.6 16.8 GO:1990402 embryonic liver development(GO:1990402)
5.5 11.0 GO:0006833 water transport(GO:0006833)
5.4 16.1 GO:0046687 response to chromate(GO:0046687)
5.3 10.6 GO:1904580 regulation of intracellular mRNA localization(GO:1904580)
5.3 31.8 GO:0006642 triglyceride mobilization(GO:0006642)
5.3 15.9 GO:0090187 pancreatic amylase secretion(GO:0036395) positive regulation of pancreatic juice secretion(GO:0090187) regulation of pancreatic amylase secretion(GO:1902276) positive regulation of histamine secretion by mast cell(GO:1903595)
5.3 37.1 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
5.3 47.5 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
5.2 15.7 GO:1904823 purine nucleobase transmembrane transport(GO:1904823)
5.2 21.0 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
5.2 20.9 GO:1903849 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
5.2 20.9 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
5.1 10.2 GO:0006552 leucine catabolic process(GO:0006552)
5.1 25.6 GO:0061144 alveolar secondary septum development(GO:0061144)
5.1 15.3 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
5.0 20.0 GO:0003343 proepicardium development(GO:0003342) septum transversum development(GO:0003343)
5.0 123.9 GO:0006956 complement activation(GO:0006956)
4.9 14.8 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
4.9 19.6 GO:0071332 cellular response to fructose stimulus(GO:0071332)
4.8 87.0 GO:0015721 bile acid and bile salt transport(GO:0015721)
4.8 14.3 GO:0045751 release of cytoplasmic sequestered NF-kappaB(GO:0008588) regulation of Toll signaling pathway(GO:0008592) negative regulation of Toll signaling pathway(GO:0045751)
4.7 19.0 GO:0030638 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
4.7 33.1 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
4.7 14.2 GO:0006649 phospholipid transfer to membrane(GO:0006649)
4.7 14.1 GO:0006543 glutamine catabolic process(GO:0006543)
4.7 51.6 GO:0042448 progesterone metabolic process(GO:0042448)
4.7 18.7 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
4.7 18.6 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
4.7 214.2 GO:0006953 acute-phase response(GO:0006953)
4.6 13.8 GO:0046356 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
4.6 36.5 GO:0070327 thyroid hormone transport(GO:0070327)
4.6 22.8 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
4.5 13.5 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
4.4 31.1 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
4.4 17.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
4.4 52.7 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
4.4 13.1 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
4.3 12.9 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
4.3 34.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
4.3 8.5 GO:0021524 visceral motor neuron differentiation(GO:0021524)
4.2 42.0 GO:0018298 protein-chromophore linkage(GO:0018298)
4.2 12.5 GO:0006045 N-acetylglucosamine biosynthetic process(GO:0006045) N-acetylneuraminate biosynthetic process(GO:0046380)
4.1 36.7 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
4.0 44.3 GO:0046415 urate metabolic process(GO:0046415)
4.0 8.0 GO:0033864 positive regulation of NAD(P)H oxidase activity(GO:0033864)
4.0 12.1 GO:0044375 regulation of peroxisome size(GO:0044375)
4.0 44.0 GO:0042574 retinal metabolic process(GO:0042574)
4.0 11.9 GO:0009758 carbohydrate utilization(GO:0009758)
4.0 11.9 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
3.9 15.8 GO:0042436 tryptophan catabolic process(GO:0006569) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
3.9 23.4 GO:0006570 tyrosine metabolic process(GO:0006570)
3.9 3.9 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
3.8 11.5 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897) negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
3.8 15.3 GO:1902896 terminal web assembly(GO:1902896)
3.8 11.5 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
3.7 14.9 GO:0042723 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
3.7 11.1 GO:1903000 regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002) lipid transport across blood brain barrier(GO:1990379)
3.7 25.7 GO:0045714 regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
3.6 25.3 GO:0006477 protein sulfation(GO:0006477)
3.6 7.2 GO:0045608 negative regulation of auditory receptor cell differentiation(GO:0045608)
3.6 10.7 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
3.5 21.2 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
3.5 3.5 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
3.5 7.1 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
3.5 7.0 GO:1990009 retinal cell apoptotic process(GO:1990009)
3.5 10.5 GO:0019303 D-ribose catabolic process(GO:0019303)
3.5 10.4 GO:0097052 L-kynurenine metabolic process(GO:0097052)
3.4 31.0 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
3.4 27.6 GO:0034312 diol biosynthetic process(GO:0034312)
3.4 75.0 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
3.4 13.5 GO:0046351 disaccharide biosynthetic process(GO:0046351)
3.4 16.8 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
3.3 10.0 GO:0010966 regulation of phosphate transport(GO:0010966)
3.3 9.9 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
3.3 19.7 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
3.3 9.8 GO:0061744 motor behavior(GO:0061744)
3.3 26.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
3.3 9.8 GO:0071623 negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024)
3.2 13.0 GO:1990839 response to endothelin(GO:1990839) cellular response to endothelin(GO:1990859)
3.2 35.7 GO:0097264 self proteolysis(GO:0097264)
3.2 6.4 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
3.2 9.7 GO:0010813 neuropeptide catabolic process(GO:0010813)
3.2 9.6 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
3.2 9.6 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
3.2 6.4 GO:0015746 citrate transport(GO:0015746)
3.1 6.3 GO:0071681 cellular response to indole-3-methanol(GO:0071681)
3.1 15.6 GO:0006741 NADP biosynthetic process(GO:0006741)
3.1 15.6 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
3.1 12.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
3.1 33.8 GO:0060046 regulation of acrosome reaction(GO:0060046)
3.1 12.2 GO:0072053 renal inner medulla development(GO:0072053)
3.1 12.2 GO:0006004 fucose metabolic process(GO:0006004)
3.0 12.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
3.0 39.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
3.0 8.9 GO:0043605 cellular amide catabolic process(GO:0043605)
3.0 5.9 GO:1901078 negative regulation of relaxation of muscle(GO:1901078)
3.0 14.8 GO:0015889 cobalamin transport(GO:0015889)
2.9 5.9 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
2.9 2.9 GO:0070428 regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
2.9 11.7 GO:0060178 regulation of exocyst localization(GO:0060178)
2.9 8.8 GO:1903769 negative regulation of cell proliferation in bone marrow(GO:1903769)
2.9 17.5 GO:0070541 response to platinum ion(GO:0070541)
2.9 17.2 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
2.9 11.4 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
2.8 8.4 GO:1901420 negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420)
2.8 8.4 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
2.8 8.3 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
2.7 5.4 GO:0072156 distal tubule morphogenesis(GO:0072156)
2.7 16.1 GO:0072615 interleukin-17 secretion(GO:0072615)
2.7 8.0 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
2.7 13.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
2.7 8.0 GO:1903181 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
2.7 8.0 GO:0032679 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
2.7 5.3 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
2.6 42.2 GO:0071872 cellular response to epinephrine stimulus(GO:0071872)
2.6 34.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
2.6 13.1 GO:0001582 detection of chemical stimulus involved in sensory perception of sweet taste(GO:0001582)
2.6 5.2 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
2.6 17.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
2.6 5.1 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
2.5 7.6 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
2.5 7.5 GO:0048550 negative regulation of pinocytosis(GO:0048550)
2.5 115.1 GO:0006635 fatty acid beta-oxidation(GO:0006635)
2.5 24.9 GO:0002934 desmosome organization(GO:0002934)
2.5 7.4 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
2.5 83.4 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
2.4 41.4 GO:0010818 T cell chemotaxis(GO:0010818)
2.4 7.3 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
2.4 12.1 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
2.4 9.5 GO:0003383 apical constriction(GO:0003383)
2.4 7.1 GO:0032532 regulation of microvillus length(GO:0032532)
2.4 9.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
2.4 4.7 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
2.4 2.4 GO:0034971 histone H3-R17 methylation(GO:0034971)
2.4 28.2 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
2.4 9.4 GO:0010424 DNA methylation on cytosine within a CG sequence(GO:0010424)
2.3 50.9 GO:0008206 bile acid metabolic process(GO:0008206)
2.3 6.9 GO:0048382 dorsal/ventral axon guidance(GO:0033563) mesendoderm development(GO:0048382)
2.3 13.8 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
2.3 6.9 GO:1901873 regulation of post-translational protein modification(GO:1901873)
2.3 29.8 GO:0034063 stress granule assembly(GO:0034063)
2.3 6.8 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
2.3 27.2 GO:0014883 transition between fast and slow fiber(GO:0014883)
2.2 6.7 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
2.2 26.7 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
2.2 15.5 GO:0060449 bud elongation involved in lung branching(GO:0060449)
2.2 6.6 GO:0018094 protein polyglycylation(GO:0018094)
2.2 8.8 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
2.2 6.6 GO:0035622 intrahepatic bile duct development(GO:0035622)
2.2 21.9 GO:0070633 transepithelial transport(GO:0070633)
2.2 10.9 GO:1904717 regulation of AMPA glutamate receptor clustering(GO:1904717)
2.2 10.8 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
2.2 6.5 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
2.2 21.5 GO:0045056 transcytosis(GO:0045056)
2.1 15.0 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
2.1 14.7 GO:0072506 phosphate ion homeostasis(GO:0055062) trivalent inorganic anion homeostasis(GO:0072506)
2.1 8.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
2.1 4.2 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
2.1 8.3 GO:1901382 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
2.1 6.2 GO:0002604 regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
2.0 18.4 GO:0035372 protein localization to microtubule(GO:0035372)
2.0 8.1 GO:0015884 folic acid transport(GO:0015884)
2.0 6.1 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
2.0 6.0 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
1.9 13.5 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418)
1.9 5.8 GO:0035973 aggrephagy(GO:0035973)
1.9 15.4 GO:0060056 mammary gland involution(GO:0060056)
1.9 3.8 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
1.9 5.7 GO:0010037 response to carbon dioxide(GO:0010037)
1.9 3.8 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
1.9 5.7 GO:0034241 positive regulation of macrophage fusion(GO:0034241)
1.9 11.3 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
1.9 11.3 GO:0015670 carbon dioxide transport(GO:0015670)
1.9 11.1 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
1.8 20.2 GO:0016540 protein autoprocessing(GO:0016540)
1.8 11.0 GO:0061074 regulation of neural retina development(GO:0061074)
1.8 12.8 GO:0043686 co-translational protein modification(GO:0043686)
1.8 1.8 GO:2000410 regulation of thymocyte migration(GO:2000410)
1.8 7.2 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
1.8 7.2 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087)
1.8 42.9 GO:0001523 retinoid metabolic process(GO:0001523)
1.8 23.2 GO:0006517 protein deglycosylation(GO:0006517)
1.8 22.9 GO:1903140 regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
1.8 5.3 GO:0060375 regulation of mast cell differentiation(GO:0060375)
1.8 26.4 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
1.7 10.5 GO:0038161 prolactin signaling pathway(GO:0038161)
1.7 24.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
1.7 5.2 GO:0080144 amino acid homeostasis(GO:0080144)
1.7 5.2 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
1.7 6.9 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
1.7 5.1 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
1.7 18.8 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
1.7 3.4 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
1.7 23.8 GO:0010040 response to iron(II) ion(GO:0010040)
1.7 11.9 GO:1903624 regulation of DNA catabolic process(GO:1903624)
1.7 6.7 GO:1990164 DNA damage response, detection of DNA damage(GO:0042769) histone H2A phosphorylation(GO:1990164)
1.7 3.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
1.7 36.7 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
1.7 5.0 GO:0001712 ectodermal cell fate commitment(GO:0001712)
1.7 6.6 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
1.7 5.0 GO:0070295 renal water absorption(GO:0070295)
1.6 4.8 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786) positive regulation of antibacterial peptide production(GO:0002803)
1.6 4.8 GO:0097298 regulation of nucleus size(GO:0097298)
1.6 22.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
1.6 4.8 GO:0071422 succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
1.6 39.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
1.5 7.7 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
1.5 18.4 GO:0001778 plasma membrane repair(GO:0001778)
1.5 24.5 GO:0002675 positive regulation of acute inflammatory response(GO:0002675)
1.5 7.5 GO:0071918 urea transmembrane transport(GO:0071918)
1.5 12.0 GO:0019388 galactose catabolic process(GO:0019388)
1.5 3.0 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
1.5 4.5 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
1.5 4.4 GO:0046100 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
1.5 16.2 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
1.5 10.2 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
1.4 15.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
1.4 18.5 GO:0006491 N-glycan processing(GO:0006491)
1.4 11.2 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
1.4 1.4 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
1.4 5.5 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
1.4 4.1 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
1.4 2.7 GO:2001226 negative regulation of chloride transport(GO:2001226)
1.4 5.5 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
1.4 4.1 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
1.4 8.2 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
1.3 13.5 GO:0016266 O-glycan processing(GO:0016266)
1.3 4.0 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
1.3 4.0 GO:0038086 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
1.3 9.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
1.3 5.3 GO:0007525 somatic muscle development(GO:0007525)
1.3 4.0 GO:0060214 endocardium formation(GO:0060214)
1.3 5.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
1.3 5.2 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
1.3 3.9 GO:0046368 GDP-L-fucose biosynthetic process(GO:0042350) GDP-L-fucose metabolic process(GO:0046368)
1.3 16.7 GO:0043129 surfactant homeostasis(GO:0043129)
1.3 3.8 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
1.3 3.8 GO:0016240 autophagosome docking(GO:0016240)
1.3 6.4 GO:0070202 regulation of establishment of protein localization to chromosome(GO:0070202)
1.3 3.8 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
1.3 7.5 GO:0071639 positive regulation of monocyte chemotactic protein-1 production(GO:0071639)
1.3 3.8 GO:1904313 response to methamphetamine hydrochloride(GO:1904313)
1.3 6.3 GO:0060263 regulation of respiratory burst(GO:0060263)
1.2 3.7 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
1.2 3.7 GO:0006116 NADH oxidation(GO:0006116)
1.2 16.0 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
1.2 8.4 GO:0072350 tricarboxylic acid metabolic process(GO:0072350)
1.2 2.4 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
1.2 9.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
1.2 4.7 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
1.2 2.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
1.2 7.0 GO:0071763 nuclear membrane organization(GO:0071763)
1.2 10.5 GO:0006689 ganglioside catabolic process(GO:0006689)
1.2 13.9 GO:0007028 cytoplasm organization(GO:0007028)
1.1 2.3 GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257)
1.1 3.4 GO:0060488 dichotomous subdivision of terminal units involved in lung branching(GO:0060448) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
1.1 17.1 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
1.1 6.8 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
1.1 2.3 GO:0072338 creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
1.1 5.7 GO:0006685 sphingomyelin catabolic process(GO:0006685)
1.1 10.1 GO:0098880 maintenance of postsynaptic specialization structure(GO:0098880) maintenance of postsynaptic density structure(GO:0099562)
1.1 18.6 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
1.1 3.3 GO:1990401 regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling(GO:0060683) embryonic lung development(GO:1990401)
1.1 6.5 GO:0031584 activation of phospholipase D activity(GO:0031584)
1.1 5.4 GO:1903960 negative regulation of anion channel activity(GO:0010360) negative regulation of anion transmembrane transport(GO:1903960)
1.1 2.2 GO:0030824 negative regulation of cGMP metabolic process(GO:0030824)
1.1 15.1 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
1.1 5.4 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
1.1 64.4 GO:0045454 cell redox homeostasis(GO:0045454)
1.1 5.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
1.1 8.6 GO:0006021 inositol biosynthetic process(GO:0006021)
1.1 2.1 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
1.1 4.2 GO:0045346 MHC class II biosynthetic process(GO:0045342) regulation of MHC class II biosynthetic process(GO:0045346)
1.0 5.2 GO:0038171 cannabinoid signaling pathway(GO:0038171)
1.0 6.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
1.0 7.3 GO:0070849 response to epidermal growth factor(GO:0070849)
1.0 13.5 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
1.0 7.2 GO:0035881 amacrine cell differentiation(GO:0035881)
1.0 4.1 GO:0097491 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
1.0 3.0 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
1.0 8.1 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
1.0 7.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
1.0 2.0 GO:0036023 embryonic skeletal limb joint morphogenesis(GO:0036023)
1.0 2.0 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
1.0 36.1 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
1.0 4.0 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
1.0 6.0 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
1.0 7.8 GO:0060481 lobar bronchus epithelium development(GO:0060481) lobar bronchus development(GO:0060482)
1.0 4.9 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
1.0 2.9 GO:0002071 glandular epithelial cell maturation(GO:0002071)
1.0 141.6 GO:0007596 blood coagulation(GO:0007596)
1.0 3.8 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
1.0 4.8 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
1.0 1.0 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.9 4.7 GO:0097278 complement-dependent cytotoxicity(GO:0097278) regulation of complement-dependent cytotoxicity(GO:1903659)
0.9 16.9 GO:1902652 secondary alcohol metabolic process(GO:1902652)
0.9 6.5 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.9 19.5 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.9 26.1 GO:0031018 endocrine pancreas development(GO:0031018)
0.9 3.7 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.9 3.7 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.9 3.7 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.9 12.0 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.9 1.8 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.9 0.9 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.9 19.0 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.9 9.9 GO:0034389 lipid particle organization(GO:0034389)
0.9 25.2 GO:0006972 hyperosmotic response(GO:0006972)
0.9 9.0 GO:0045606 positive regulation of epidermal cell differentiation(GO:0045606)
0.9 3.6 GO:0018344 protein geranylgeranylation(GO:0018344)
0.9 10.7 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.9 0.9 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.9 2.7 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.9 31.4 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.9 13.0 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.9 3.5 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.9 3.4 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.9 1.7 GO:0036102 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.8 12.7 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.8 5.9 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.8 2.5 GO:0046655 folic acid metabolic process(GO:0046655)
0.8 16.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.8 6.6 GO:0046548 retinal rod cell development(GO:0046548)
0.8 6.5 GO:0015886 heme transport(GO:0015886)
0.8 7.3 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.8 7.3 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.8 7.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.8 9.6 GO:0048368 lateral mesoderm development(GO:0048368)
0.8 10.3 GO:0010575 positive regulation of vascular endothelial growth factor production(GO:0010575)
0.8 4.0 GO:0045218 zonula adherens maintenance(GO:0045218)
0.8 1.6 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.8 3.9 GO:0051572 negative regulation of histone H3-K4 methylation(GO:0051572)
0.8 3.9 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.8 5.5 GO:0034214 protein hexamerization(GO:0034214)
0.8 4.7 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.8 1.5 GO:0002741 positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.8 10.7 GO:0002227 innate immune response in mucosa(GO:0002227)
0.8 13.0 GO:0033327 Leydig cell differentiation(GO:0033327)
0.8 3.8 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.7 20.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.7 2.9 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.7 6.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.7 2.2 GO:0045210 negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210) negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.7 4.3 GO:0032727 positive regulation of interferon-alpha production(GO:0032727)
0.7 2.8 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.7 6.4 GO:0032790 ribosome disassembly(GO:0032790)
0.7 3.5 GO:0045006 DNA deamination(GO:0045006)
0.7 17.4 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.7 4.8 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.7 6.8 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.7 24.2 GO:0016126 sterol biosynthetic process(GO:0016126)
0.7 22.4 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.7 2.0 GO:2000195 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162) negative regulation of female gonad development(GO:2000195)
0.7 2.0 GO:1903413 response to bile acid(GO:1903412) cellular response to bile acid(GO:1903413)
0.7 0.7 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.7 3.9 GO:0060023 hard palate development(GO:0060022) soft palate development(GO:0060023)
0.6 6.5 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.6 6.4 GO:0003148 outflow tract septum morphogenesis(GO:0003148)
0.6 10.9 GO:0070166 enamel mineralization(GO:0070166)
0.6 3.2 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.6 4.4 GO:0007144 female meiosis I(GO:0007144)
0.6 6.9 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.6 2.5 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.6 5.0 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.6 4.9 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.6 3.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.6 12.9 GO:0006098 pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.6 3.0 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.6 3.0 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.6 1.8 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine to uridine editing(GO:0016554) cytidine metabolic process(GO:0046087)
0.6 6.6 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.6 1.8 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.6 10.2 GO:0032801 receptor catabolic process(GO:0032801)
0.6 8.3 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.6 2.4 GO:0052695 cellular glucuronidation(GO:0052695)
0.6 4.7 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.6 1.7 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.6 1.2 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.6 3.4 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.6 50.5 GO:0007586 digestion(GO:0007586)
0.6 1.7 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.6 3.9 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.6 1.1 GO:0002215 defense response to nematode(GO:0002215)
0.6 3.9 GO:0006228 UTP biosynthetic process(GO:0006228)
0.6 5.6 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.5 4.3 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.5 3.8 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.5 10.9 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.5 8.3 GO:0019835 cytolysis(GO:0019835)
0.5 2.6 GO:0060005 vestibular reflex(GO:0060005)
0.5 4.7 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.5 5.2 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.5 4.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.5 3.1 GO:0040031 snRNA modification(GO:0040031)
0.5 2.1 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.5 2.0 GO:0060396 growth hormone receptor signaling pathway(GO:0060396)
0.5 0.5 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.5 4.5 GO:0050912 detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.5 1.5 GO:0051684 maintenance of Golgi location(GO:0051684)
0.5 3.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.5 1.0 GO:0009227 nucleotide-sugar catabolic process(GO:0009227)
0.5 2.9 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.5 10.7 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.5 1.0 GO:0048859 formation of anatomical boundary(GO:0048859)
0.5 1.4 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.5 4.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.5 4.7 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.5 4.2 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.5 4.7 GO:0002024 diet induced thermogenesis(GO:0002024)
0.5 2.8 GO:0046519 sphingoid metabolic process(GO:0046519)
0.5 0.9 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.5 0.9 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.5 2.8 GO:0051182 coenzyme transport(GO:0051182)
0.5 6.0 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.5 1.4 GO:1903406 positive regulation of synaptic growth at neuromuscular junction(GO:0045887) regulation of sodium:potassium-exchanging ATPase activity(GO:1903406) regulation of protein geranylgeranylation(GO:2000539) positive regulation of protein geranylgeranylation(GO:2000541)
0.5 2.7 GO:0015695 organic cation transport(GO:0015695)
0.5 1.8 GO:0060014 granulosa cell differentiation(GO:0060014)
0.5 4.1 GO:0019395 fatty acid oxidation(GO:0019395)
0.5 3.6 GO:2000210 positive regulation of anoikis(GO:2000210)
0.4 2.7 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.4 2.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.4 24.2 GO:0043648 dicarboxylic acid metabolic process(GO:0043648)
0.4 1.7 GO:0019563 glycerol catabolic process(GO:0019563)
0.4 4.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.4 5.6 GO:0046931 pore complex assembly(GO:0046931) nuclear pore complex assembly(GO:0051292)
0.4 1.7 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.4 3.0 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.4 11.8 GO:0030858 positive regulation of epithelial cell differentiation(GO:0030858)
0.4 0.8 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.4 22.0 GO:0055088 lipid homeostasis(GO:0055088)
0.4 6.6 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.4 4.1 GO:0032527 protein exit from endoplasmic reticulum(GO:0032527)
0.4 1.2 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.4 0.8 GO:0038007 netrin-activated signaling pathway(GO:0038007) actin filament bundle distribution(GO:0070650)
0.4 21.2 GO:0046849 bone remodeling(GO:0046849)
0.4 1.2 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.4 11.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.4 2.7 GO:0009081 branched-chain amino acid metabolic process(GO:0009081)
0.4 2.3 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.4 7.6 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.4 8.9 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.4 4.0 GO:0042407 cristae formation(GO:0042407)
0.4 3.3 GO:0006622 protein targeting to lysosome(GO:0006622)
0.4 6.1 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.4 0.7 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.4 2.8 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.3 0.7 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.3 1.7 GO:0060179 male mating behavior(GO:0060179)
0.3 6.6 GO:0048240 sperm capacitation(GO:0048240)
0.3 3.4 GO:0072678 T cell migration(GO:0072678)
0.3 2.4 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.3 2.7 GO:0048535 lymph node development(GO:0048535)
0.3 6.2 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.3 5.5 GO:1902235 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902235)
0.3 4.4 GO:0030828 positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828)
0.3 1.0 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.3 2.7 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.3 1.3 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.3 6.3 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.3 3.6 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.3 2.2 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.3 3.7 GO:0006265 DNA topological change(GO:0006265)
0.3 3.4 GO:0051639 actin filament network formation(GO:0051639)
0.3 2.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.3 2.1 GO:0002115 store-operated calcium entry(GO:0002115)
0.3 1.5 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.3 2.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.3 1.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.3 5.0 GO:0009395 phospholipid catabolic process(GO:0009395)
0.3 0.9 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.3 0.8 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.3 0.8 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.3 0.5 GO:1903918 regulation of actin filament severing(GO:1903918) negative regulation of actin filament severing(GO:1903919)
0.3 2.9 GO:0052472 modulation by host of viral transcription(GO:0043921) modulation of transcription in other organism involved in symbiotic interaction(GO:0052312) modulation by host of symbiont transcription(GO:0052472)
0.3 2.1 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.3 1.3 GO:0003417 growth plate cartilage development(GO:0003417)
0.3 34.9 GO:0031668 cellular response to extracellular stimulus(GO:0031668)
0.3 8.9 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.3 10.1 GO:0019882 antigen processing and presentation(GO:0019882)
0.3 1.3 GO:0046466 membrane lipid catabolic process(GO:0046466)
0.3 3.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 4.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 2.2 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.2 0.7 GO:0009624 response to nematode(GO:0009624)
0.2 0.7 GO:0070269 pyroptosis(GO:0070269)
0.2 0.7 GO:0046208 spermine catabolic process(GO:0046208)
0.2 1.5 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.2 10.2 GO:0032543 mitochondrial translation(GO:0032543)
0.2 0.7 GO:0002644 negative regulation of tolerance induction(GO:0002644)
0.2 2.6 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.2 123.1 GO:0055114 oxidation-reduction process(GO:0055114)
0.2 0.7 GO:1990108 protein linear deubiquitination(GO:1990108)
0.2 5.9 GO:1901998 toxin transport(GO:1901998)
0.2 0.9 GO:0032740 positive regulation of interleukin-17 production(GO:0032740)
0.2 0.9 GO:0019430 removal of superoxide radicals(GO:0019430)
0.2 0.8 GO:0050667 homocysteine metabolic process(GO:0050667)
0.2 1.7 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.2 1.2 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.2 0.4 GO:0043032 positive regulation of macrophage activation(GO:0043032)
0.2 1.6 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.2 1.0 GO:0032262 pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206)
0.2 0.6 GO:0035036 sperm-egg recognition(GO:0035036)
0.2 1.4 GO:0033623 regulation of integrin activation(GO:0033623)
0.2 1.0 GO:0051661 maintenance of centrosome location(GO:0051661)
0.2 0.6 GO:0003416 endochondral bone growth(GO:0003416) bone growth(GO:0098868)
0.2 0.2 GO:0042222 interleukin-1 biosynthetic process(GO:0042222)
0.2 4.9 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.2 1.3 GO:0032482 Rab protein signal transduction(GO:0032482)
0.2 5.0 GO:0018149 peptide cross-linking(GO:0018149)
0.2 1.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.2 6.3 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.2 0.3 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.2 1.3 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.2 5.6 GO:2001222 regulation of neuron migration(GO:2001222)
0.2 16.5 GO:0006790 sulfur compound metabolic process(GO:0006790)
0.2 5.7 GO:0050909 sensory perception of taste(GO:0050909)
0.2 0.6 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.1 191.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 0.1 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.1 0.7 GO:0090367 negative regulation of mRNA modification(GO:0090367)
0.1 2.3 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 2.8 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 0.7 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 1.3 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 0.9 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.4 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.1 0.7 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.1 1.0 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.1 0.6 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 1.7 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.1 0.2 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.1 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.3 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 1.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 2.0 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.1 1.2 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.1 1.1 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 0.9 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 0.3 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.5 GO:0045116 protein neddylation(GO:0045116)
0.1 1.9 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.1 3.5 GO:0051028 mRNA transport(GO:0051028)
0.0 0.6 GO:0045109 intermediate filament organization(GO:0045109)
0.0 1.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.5 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.4 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.8 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.0 0.2 GO:0046688 response to copper ion(GO:0046688)
0.0 0.1 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.2 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.3 GO:0048538 thymus development(GO:0048538)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
25.4 228.3 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
23.1 69.4 GO:0046691 intracellular canaliculus(GO:0046691)
14.5 101.4 GO:0005579 membrane attack complex(GO:0005579)
11.1 44.5 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
10.8 86.6 GO:0005577 fibrinogen complex(GO:0005577)
10.3 31.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
10.2 203.3 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
9.6 47.8 GO:0097413 Lewy body(GO:0097413)
9.5 56.8 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
9.2 46.2 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
8.7 26.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
8.4 33.5 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
7.8 31.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
7.5 7.5 GO:0071914 prominosome(GO:0071914)
7.1 35.5 GO:0061689 tricellular tight junction(GO:0061689)
6.9 34.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
5.3 15.9 GO:0035577 azurophil granule membrane(GO:0035577)
5.0 80.8 GO:0070852 cell body fiber(GO:0070852)
5.0 20.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
4.6 18.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
4.5 31.8 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
4.2 20.9 GO:1990769 proximal neuron projection(GO:1990769)
4.1 28.6 GO:0071438 invadopodium membrane(GO:0071438)
4.0 425.0 GO:0072562 blood microparticle(GO:0072562)
3.8 3.8 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
3.6 32.0 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
3.3 9.9 GO:0061474 phagolysosome membrane(GO:0061474)
3.1 21.7 GO:0090543 Flemming body(GO:0090543)
2.8 11.3 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
2.8 183.6 GO:0044438 microbody part(GO:0044438) peroxisomal part(GO:0044439)
2.7 136.8 GO:0055038 recycling endosome membrane(GO:0055038)
2.7 8.0 GO:0032398 MHC class Ib protein complex(GO:0032398)
2.6 13.1 GO:1903767 sweet taste receptor complex(GO:1903767) taste receptor complex(GO:1903768)
2.6 13.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
2.5 12.7 GO:0009925 basal plasma membrane(GO:0009925)
2.5 30.0 GO:0031983 vesicle lumen(GO:0031983)
2.5 222.5 GO:0031526 brush border membrane(GO:0031526)
2.4 167.4 GO:0005811 lipid particle(GO:0005811)
2.4 165.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
2.3 18.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
2.3 9.2 GO:0036156 inner dynein arm(GO:0036156)
2.3 189.9 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
2.3 13.5 GO:0097422 tubular endosome(GO:0097422)
2.2 6.6 GO:0035838 growing cell tip(GO:0035838)
2.2 38.8 GO:0031091 platelet alpha granule(GO:0031091)
2.1 166.0 GO:0005903 brush border(GO:0005903)
2.1 6.2 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
2.0 6.0 GO:0005899 insulin receptor complex(GO:0005899)
2.0 16.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
2.0 6.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
2.0 9.9 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
1.9 31.0 GO:0045180 basal cortex(GO:0045180)
1.8 18.3 GO:0002177 manchette(GO:0002177)
1.8 7.2 GO:1990005 granular vesicle(GO:1990005)
1.7 10.4 GO:1990111 spermatoproteasome complex(GO:1990111)
1.7 45.7 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
1.7 20.0 GO:0005861 troponin complex(GO:0005861)
1.6 4.9 GO:0002178 palmitoyltransferase complex(GO:0002178)
1.6 9.5 GO:0033269 internode region of axon(GO:0033269)
1.6 22.1 GO:0044215 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
1.6 1114.4 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
1.5 6.1 GO:0045098 type III intermediate filament(GO:0045098)
1.5 21.0 GO:0042612 MHC class I protein complex(GO:0042612)
1.4 37.4 GO:0045120 pronucleus(GO:0045120)
1.4 4.1 GO:0071942 XPC complex(GO:0071942)
1.4 9.6 GO:0032591 dendritic spine membrane(GO:0032591)
1.4 4.1 GO:0070421 DNA ligase III-XRCC1 complex(GO:0070421)
1.3 6.5 GO:0033093 Weibel-Palade body(GO:0033093)
1.3 3.9 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
1.2 9.9 GO:0043020 NADPH oxidase complex(GO:0043020)
1.2 4.9 GO:0005927 muscle tendon junction(GO:0005927)
1.2 4.8 GO:0097209 epidermal lamellar body(GO:0097209)
1.2 1.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
1.1 31.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
1.1 10.2 GO:0005915 zonula adherens(GO:0005915)
1.1 2.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
1.1 10.7 GO:0044754 autolysosome(GO:0044754)
1.1 24.4 GO:0042588 zymogen granule(GO:0042588)
1.1 53.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
1.1 9.5 GO:0097208 alveolar lamellar body(GO:0097208)
1.1 12.7 GO:0030127 COPII vesicle coat(GO:0030127)
1.0 1400.0 GO:0005615 extracellular space(GO:0005615)
1.0 9.3 GO:0071141 SMAD protein complex(GO:0071141)
1.0 318.1 GO:0005759 mitochondrial matrix(GO:0005759)
1.0 17.7 GO:0030057 desmosome(GO:0030057)
1.0 2.9 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
1.0 3.9 GO:0072487 MSL complex(GO:0072487)
0.9 3.7 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.9 5.5 GO:0071439 clathrin complex(GO:0071439)
0.9 27.8 GO:0005902 microvillus(GO:0005902)
0.9 1.8 GO:0055087 Ski complex(GO:0055087)
0.9 6.9 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.8 11.0 GO:0031362 intrinsic component of external side of plasma membrane(GO:0031233) anchored component of external side of plasma membrane(GO:0031362)
0.8 5.9 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.8 4.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.8 18.8 GO:0008305 integrin complex(GO:0008305)
0.8 4.7 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.8 4.7 GO:0031595 nuclear proteasome complex(GO:0031595)
0.8 6.1 GO:0005614 interstitial matrix(GO:0005614)
0.8 3.8 GO:0000138 Golgi trans cisterna(GO:0000138)
0.8 9.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.7 10.8 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.7 1.4 GO:0030056 hemidesmosome(GO:0030056)
0.7 4.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.7 27.1 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.7 3.9 GO:0043202 lysosomal lumen(GO:0043202)
0.6 3.9 GO:0043219 lateral loop(GO:0043219)
0.6 4.5 GO:0005833 hemoglobin complex(GO:0005833)
0.6 16.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.6 4.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.6 9.3 GO:0042611 MHC protein complex(GO:0042611)
0.6 15.9 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.6 4.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.6 11.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.6 3.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.6 1.7 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.6 2.3 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.6 136.5 GO:0016324 apical plasma membrane(GO:0016324)
0.6 2.8 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.6 18.0 GO:0005604 basement membrane(GO:0005604)
0.5 3.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.5 4.7 GO:0032009 early phagosome(GO:0032009)
0.5 77.3 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.5 22.6 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.5 83.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.5 9.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.5 9.3 GO:0005581 collagen trimer(GO:0005581)
0.4 7.2 GO:0000421 autophagosome membrane(GO:0000421)
0.4 3.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.4 792.0 GO:0070062 extracellular exosome(GO:0070062)
0.4 5.4 GO:0000801 central element(GO:0000801)
0.4 3.7 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.4 13.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.4 3.8 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.4 2.6 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.4 1.8 GO:0031902 late endosome membrane(GO:0031902)
0.3 3.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.3 27.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.3 4.5 GO:0001533 cornified envelope(GO:0001533)
0.3 1.7 GO:0031264 death-inducing signaling complex(GO:0031264)
0.3 67.0 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.3 2.9 GO:0030914 STAGA complex(GO:0030914)
0.3 8.1 GO:0000791 euchromatin(GO:0000791)
0.2 2.2 GO:0001772 immunological synapse(GO:0001772)
0.2 47.4 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.2 1.1 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.2 0.6 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.2 4.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.2 1.7 GO:0016580 Sin3 complex(GO:0016580)
0.2 2.0 GO:0017119 Golgi transport complex(GO:0017119)
0.2 3.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 2.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.2 0.9 GO:0030896 checkpoint clamp complex(GO:0030896)
0.2 0.8 GO:0098536 deuterosome(GO:0098536)
0.1 47.1 GO:0005667 transcription factor complex(GO:0005667)
0.1 0.7 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 1.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.4 GO:0030689 Noc complex(GO:0030689)
0.1 1.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.8 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.9 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 1.2 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.7 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
48.4 145.1 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
41.6 124.7 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
30.0 120.0 GO:0047619 acylcarnitine hydrolase activity(GO:0047619)
25.2 75.7 GO:0008520 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
25.0 200.4 GO:0008172 S-methyltransferase activity(GO:0008172)
22.4 67.2 GO:0008405 arachidonic acid 11,12-epoxygenase activity(GO:0008405)
22.1 88.3 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
21.9 218.5 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
21.7 21.7 GO:0050294 steroid sulfotransferase activity(GO:0050294)
21.3 85.0 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
20.1 823.8 GO:0070330 aromatase activity(GO:0070330)
19.6 58.7 GO:0004657 proline dehydrogenase activity(GO:0004657)
19.5 58.5 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
19.3 19.3 GO:0015350 methotrexate transporter activity(GO:0015350)
18.5 129.5 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
18.3 165.0 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
17.2 51.6 GO:0004046 aminoacylase activity(GO:0004046)
17.1 68.3 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
16.9 50.7 GO:0008458 carnitine O-octanoyltransferase activity(GO:0008458) O-octanoyltransferase activity(GO:0016414)
15.3 61.2 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
15.3 45.8 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
15.2 45.7 GO:0000253 3-keto sterol reductase activity(GO:0000253)
14.7 88.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
14.6 73.2 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
14.5 43.5 GO:0098603 selenol Se-methyltransferase activity(GO:0098603)
14.0 181.4 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
13.2 39.7 GO:0031714 C5a anaphylatoxin chemotactic receptor binding(GO:0031714)
13.0 25.9 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
12.8 38.3 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
12.7 51.0 GO:0030294 receptor signaling protein tyrosine kinase inhibitor activity(GO:0030294)
12.6 75.8 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
11.9 47.7 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
11.7 46.6 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
11.6 92.9 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
11.3 56.3 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
11.1 77.8 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
11.0 65.7 GO:0001758 retinal dehydrogenase activity(GO:0001758)
10.6 74.2 GO:0030492 hemoglobin binding(GO:0030492)
10.4 135.1 GO:0005542 folic acid binding(GO:0005542)
10.0 50.1 GO:0005534 galactose binding(GO:0005534)
9.8 49.0 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
9.7 38.9 GO:0004967 glucagon receptor activity(GO:0004967)
9.5 28.4 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
9.4 46.9 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
9.4 37.5 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
9.3 130.4 GO:0015250 water channel activity(GO:0015250)
9.3 27.9 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
9.2 46.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
9.1 45.5 GO:0004103 choline kinase activity(GO:0004103)
9.1 18.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
9.0 44.9 GO:0035473 lipase binding(GO:0035473)
8.6 51.8 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
8.4 33.5 GO:0048408 epidermal growth factor binding(GO:0048408)
8.2 32.9 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
8.2 40.9 GO:0019862 IgA binding(GO:0019862)
7.9 31.5 GO:0030283 testosterone dehydrogenase [NAD(P)] activity(GO:0030283)
7.7 23.1 GO:0004736 pyruvate carboxylase activity(GO:0004736)
7.6 235.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
7.4 140.0 GO:0001848 complement binding(GO:0001848)
7.4 36.8 GO:0005550 pheromone binding(GO:0005550)
7.2 78.7 GO:0008242 omega peptidase activity(GO:0008242)
7.1 28.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
6.7 193.7 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
6.6 26.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
6.5 45.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
6.4 38.5 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
6.4 102.1 GO:0004745 retinol dehydrogenase activity(GO:0004745)
6.3 12.7 GO:0001847 opsonin receptor activity(GO:0001847)
6.2 18.7 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
6.2 87.0 GO:0008395 steroid hydroxylase activity(GO:0008395)
6.1 18.4 GO:0009384 N-acylmannosamine kinase activity(GO:0009384)
6.0 24.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
6.0 138.7 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
6.0 47.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
5.9 23.8 GO:0030350 iron-responsive element binding(GO:0030350)
5.9 23.6 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
5.9 29.5 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
5.9 52.8 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
5.8 40.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
5.6 50.0 GO:0031995 insulin-like growth factor II binding(GO:0031995)
5.5 38.5 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
5.4 21.5 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
5.4 16.1 GO:0008142 oxysterol binding(GO:0008142)
5.3 26.7 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
5.3 154.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
5.3 15.8 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
5.2 15.7 GO:0015205 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
5.2 67.1 GO:0070402 NADPH binding(GO:0070402)
5.1 45.5 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
4.9 122.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
4.9 19.5 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
4.8 38.7 GO:0008430 selenium binding(GO:0008430)
4.8 38.2 GO:0004565 beta-galactosidase activity(GO:0004565)
4.6 9.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
4.6 13.7 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
4.5 13.4 GO:0042296 ISG15 transferase activity(GO:0042296)
4.4 22.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
4.4 13.3 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
4.4 30.9 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
4.3 25.7 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
4.3 12.8 GO:0004655 porphobilinogen synthase activity(GO:0004655)
4.2 25.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
4.2 25.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
4.0 170.8 GO:0016831 carboxy-lyase activity(GO:0016831)
4.0 31.8 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
4.0 11.9 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
3.9 47.1 GO:0001972 retinoic acid binding(GO:0001972)
3.9 15.7 GO:0035614 snRNA stem-loop binding(GO:0035614)
3.9 11.6 GO:0019807 aspartoacylase activity(GO:0019807)
3.9 11.6 GO:0004359 glutaminase activity(GO:0004359)
3.8 433.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
3.8 15.3 GO:0035727 lysophosphatidic acid binding(GO:0035727)
3.8 7.6 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
3.8 45.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
3.8 22.7 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
3.8 11.3 GO:0016748 succinyltransferase activity(GO:0016748)
3.7 11.1 GO:0046911 metal chelating activity(GO:0046911)
3.7 14.6 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
3.7 25.6 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
3.6 14.6 GO:0004064 arylesterase activity(GO:0004064)
3.6 10.8 GO:0004911 interleukin-2 receptor activity(GO:0004911)
3.5 10.5 GO:0004925 prolactin receptor activity(GO:0004925)
3.5 31.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
3.5 17.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
3.5 38.0 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
3.4 13.8 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812)
3.4 20.3 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
3.4 174.6 GO:0038024 cargo receptor activity(GO:0038024)
3.3 20.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
3.3 727.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
3.3 39.5 GO:0019864 IgG binding(GO:0019864)
3.3 71.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
3.2 9.6 GO:0002060 purine nucleobase binding(GO:0002060) purine-nucleoside phosphorylase activity(GO:0004731)
3.2 9.6 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
3.2 6.4 GO:0015137 citrate transmembrane transporter activity(GO:0015137)
3.2 9.6 GO:0097603 temperature-gated ion channel activity(GO:0097603)
3.1 34.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
3.1 61.1 GO:0004806 triglyceride lipase activity(GO:0004806)
3.0 9.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
2.9 58.7 GO:0008199 ferric iron binding(GO:0008199)
2.9 8.8 GO:0052743 inositol tetrakisphosphate phosphatase activity(GO:0052743)
2.9 34.8 GO:0010181 FMN binding(GO:0010181)
2.9 20.1 GO:0016018 cyclosporin A binding(GO:0016018)
2.8 19.9 GO:0004957 prostaglandin E receptor activity(GO:0004957)
2.8 11.3 GO:0035514 DNA demethylase activity(GO:0035514)
2.8 22.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
2.8 16.5 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
2.7 18.9 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
2.7 13.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
2.7 45.8 GO:0015643 toxic substance binding(GO:0015643)
2.7 8.0 GO:0002114 interleukin-33 receptor activity(GO:0002114)
2.6 7.9 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
2.6 13.1 GO:0033041 sweet taste receptor activity(GO:0033041)
2.6 2.6 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
2.6 15.4 GO:0004126 cytidine deaminase activity(GO:0004126)
2.6 10.2 GO:0016421 CoA carboxylase activity(GO:0016421)
2.5 10.1 GO:0097108 hedgehog family protein binding(GO:0097108)
2.5 46.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
2.4 12.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
2.4 24.0 GO:0015923 mannosidase activity(GO:0015923)
2.4 23.9 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
2.4 9.4 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
2.3 9.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
2.3 86.7 GO:0004364 glutathione transferase activity(GO:0004364)
2.2 13.5 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
2.2 6.6 GO:0070735 protein-glycine ligase activity(GO:0070735)
2.2 33.1 GO:0035497 cAMP response element binding(GO:0035497)
2.2 19.6 GO:0070061 fructose binding(GO:0070061)
2.1 43.0 GO:0019200 carbohydrate kinase activity(GO:0019200)
2.1 10.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
2.1 8.3 GO:0031686 A1 adenosine receptor binding(GO:0031686)
2.0 14.2 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
2.0 42.5 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
2.0 6.0 GO:0017098 sulfonylurea receptor binding(GO:0017098)
2.0 9.8 GO:0048039 ubiquinone binding(GO:0048039)
2.0 5.9 GO:0070644 vitamin D response element binding(GO:0070644)
1.9 7.7 GO:0070008 serine-type carboxypeptidase activity(GO:0004185) serine-type exopeptidase activity(GO:0070008)
1.9 5.6 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
1.8 14.8 GO:0016832 aldehyde-lyase activity(GO:0016832)
1.8 16.6 GO:0008494 translation activator activity(GO:0008494)
1.8 14.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
1.8 14.5 GO:0051525 NFAT protein binding(GO:0051525)
1.8 5.4 GO:0005128 erythropoietin receptor binding(GO:0005128)
1.8 8.8 GO:0031419 cobalamin binding(GO:0031419)
1.8 28.2 GO:0017081 chloride channel regulator activity(GO:0017081)
1.8 12.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
1.7 5.2 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
1.7 38.2 GO:0042288 MHC class I protein binding(GO:0042288)
1.7 6.9 GO:0008265 Mo-molybdopterin cofactor sulfurase activity(GO:0008265)
1.7 5.1 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
1.7 5.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
1.7 5.1 GO:0004522 ribonuclease A activity(GO:0004522)
1.7 6.7 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
1.6 8.2 GO:0051373 FATZ binding(GO:0051373)
1.6 8.2 GO:1990254 keratin filament binding(GO:1990254)
1.6 24.4 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
1.6 21.0 GO:0098919 structural constituent of postsynaptic specialization(GO:0098879) structural constituent of postsynaptic density(GO:0098919)
1.6 6.4 GO:0019960 C-X3-C chemokine binding(GO:0019960)
1.6 8.0 GO:0070051 fibrinogen binding(GO:0070051)
1.6 12.7 GO:0030368 interleukin-17 receptor activity(GO:0030368)
1.6 15.8 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
1.6 4.8 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
1.5 3.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
1.5 6.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
1.5 7.5 GO:0015204 urea transmembrane transporter activity(GO:0015204)
1.5 1.5 GO:0042806 fucose binding(GO:0042806)
1.4 7.2 GO:0005148 prolactin receptor binding(GO:0005148)
1.4 18.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
1.4 11.1 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
1.4 6.9 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
1.4 5.5 GO:0055077 gap junction hemi-channel activity(GO:0055077)
1.3 4.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
1.3 5.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
1.3 6.5 GO:0046923 ER retention sequence binding(GO:0046923)
1.3 10.4 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
1.3 5.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
1.2 3.7 GO:0031770 growth hormone-releasing hormone receptor binding(GO:0031770)
1.2 3.7 GO:0032142 dinucleotide insertion or deletion binding(GO:0032139) single guanine insertion binding(GO:0032142)
1.2 16.1 GO:0003796 lysozyme activity(GO:0003796)
1.2 8.6 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
1.2 8.6 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832)
1.2 22.0 GO:0005149 interleukin-1 receptor binding(GO:0005149)
1.2 41.4 GO:0042605 peptide antigen binding(GO:0042605)
1.2 13.4 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
1.2 3.6 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
1.2 72.1 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
1.2 8.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
1.2 5.9 GO:0001155 TFIIIA-class transcription factor binding(GO:0001155)
1.2 3.5 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
1.2 9.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
1.1 19.5 GO:0008483 transaminase activity(GO:0008483)
1.1 3.3 GO:1990460 leptin receptor binding(GO:1990460)
1.1 20.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
1.1 5.5 GO:0015093 iron ion transmembrane transporter activity(GO:0005381) ferrous iron transmembrane transporter activity(GO:0015093)
1.1 6.5 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
1.0 9.4 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
1.0 6.1 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
1.0 4.0 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
1.0 126.9 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
1.0 47.6 GO:0008146 sulfotransferase activity(GO:0008146)
1.0 46.2 GO:0051213 dioxygenase activity(GO:0051213)
1.0 8.8 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
1.0 11.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.9 11.2 GO:0008097 5S rRNA binding(GO:0008097)
0.9 6.5 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.9 16.3 GO:0005522 profilin binding(GO:0005522)
0.9 3.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.9 4.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.9 13.0 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.9 2.6 GO:0070698 nodal binding(GO:0038100) type I activin receptor binding(GO:0070698)
0.9 12.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.9 1.7 GO:0050051 leukotriene-B4 20-monooxygenase activity(GO:0050051) tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871)
0.8 2.5 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.8 5.0 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.8 6.6 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.8 10.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.8 8.0 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.8 2.4 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.8 6.3 GO:0019203 carbohydrate phosphatase activity(GO:0019203) sugar-phosphatase activity(GO:0050308)
0.8 7.1 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.8 3.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.8 35.5 GO:0001221 transcription cofactor binding(GO:0001221)
0.8 3.8 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.8 3.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.8 3.8 GO:1990226 histone methyltransferase binding(GO:1990226)
0.8 2.3 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.8 15.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.7 3.7 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.7 14.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.7 2.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.7 31.0 GO:0070888 E-box binding(GO:0070888)
0.7 28.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.7 2.1 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.7 4.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.7 5.5 GO:0050897 cobalt ion binding(GO:0050897)
0.7 8.7 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.7 4.7 GO:0035325 Toll-like receptor binding(GO:0035325)
0.7 17.2 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.7 2.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.7 9.8 GO:0070410 co-SMAD binding(GO:0070410)
0.7 37.3 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.6 3.9 GO:0042289 MHC class II protein binding(GO:0042289)
0.6 6.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.6 10.9 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.6 1.3 GO:0015925 galactosidase activity(GO:0015925)
0.6 3.7 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.6 2.4 GO:0015057 thrombin receptor activity(GO:0015057)
0.6 8.8 GO:0003993 acid phosphatase activity(GO:0003993)
0.6 7.1 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451)
0.6 4.7 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.6 1.7 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.6 4.4 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.6 2.8 GO:0051185 coenzyme transporter activity(GO:0051185)
0.5 4.9 GO:0030957 Tat protein binding(GO:0030957)
0.5 45.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.5 2.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.5 31.1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.5 1.6 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.5 3.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.5 6.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.5 87.4 GO:0008168 methyltransferase activity(GO:0008168)
0.5 3.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.5 7.9 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.5 14.8 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.5 3.9 GO:0016679 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.5 5.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.5 2.9 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.5 20.4 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.5 11.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.5 3.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.5 0.9 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.5 19.4 GO:0005507 copper ion binding(GO:0005507)
0.5 3.7 GO:0043237 laminin-1 binding(GO:0043237)
0.5 1.4 GO:1990459 transferrin receptor binding(GO:1990459)
0.5 5.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.4 2.2 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.4 8.0 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.4 4.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.4 94.4 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.4 0.8 GO:0046848 hydroxyapatite binding(GO:0046848)
0.4 1.7 GO:0004630 phospholipase D activity(GO:0004630)
0.4 9.4 GO:0008527 taste receptor activity(GO:0008527)
0.4 2.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.4 12.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.4 3.7 GO:0005243 gap junction channel activity(GO:0005243)
0.4 2.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.4 1.4 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.4 4.6 GO:0005537 mannose binding(GO:0005537)
0.3 2.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.3 1.4 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.3 3.8 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.3 2.7 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.3 11.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.3 17.4 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.3 1.9 GO:1990405 protein antigen binding(GO:1990405)
0.3 2.6 GO:0001055 RNA polymerase II activity(GO:0001055)
0.3 1.6 GO:0046527 glucosyltransferase activity(GO:0046527)
0.3 3.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.3 3.4 GO:0045499 chemorepellent activity(GO:0045499)
0.3 12.2 GO:0000049 tRNA binding(GO:0000049)
0.3 12.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.3 1.2 GO:0001635 calcitonin gene-related peptide receptor activity(GO:0001635)
0.3 8.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.3 2.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.3 2.6 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.3 5.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.3 4.1 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.2 7.2 GO:0050699 WW domain binding(GO:0050699)
0.2 2.2 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.2 31.5 GO:0005179 hormone activity(GO:0005179)
0.2 12.3 GO:0043022 ribosome binding(GO:0043022)
0.2 0.7 GO:0019809 spermidine binding(GO:0019809)
0.2 2.7 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.2 2.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 5.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 3.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.2 2.9 GO:0008143 poly(A) binding(GO:0008143)
0.2 5.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 0.6 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.2 1.0 GO:0031849 olfactory receptor binding(GO:0031849)
0.2 1.0 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.2 1.1 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.2 0.7 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.2 2.7 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.2 0.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 12.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.2 1.0 GO:0004954 prostanoid receptor activity(GO:0004954)
0.2 3.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 1.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 3.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 0.6 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.2 0.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.2 3.0 GO:0004497 monooxygenase activity(GO:0004497)
0.2 1.9 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 191.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 1.0 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1 5.9 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.1 0.6 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 1.1 GO:0009881 photoreceptor activity(GO:0009881)
0.1 1.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 1.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 33.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 12.7 GO:0008083 growth factor activity(GO:0008083)
0.1 1.6 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 1.7 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 0.5 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 1.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 4.1 GO:0035326 enhancer binding(GO:0035326)
0.1 1.5 GO:0017091 AU-rich element binding(GO:0017091)
0.1 2.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.7 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 0.3 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1 0.4 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.2 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 1.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.4 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.3 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.8 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.5 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.8 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.0 GO:0016015 morphogen activity(GO:0016015)
0.0 0.2 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
9.6 297.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
8.0 440.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
5.1 75.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
2.7 129.7 PID HNF3A PATHWAY FOXA1 transcription factor network
2.6 46.6 ST G ALPHA S PATHWAY G alpha s Pathway
2.1 497.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
2.0 32.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
1.8 19.9 ST JAK STAT PATHWAY Jak-STAT Pathway
1.7 32.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
1.7 11.8 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
1.6 32.9 PID EPO PATHWAY EPO signaling pathway
1.5 7.6 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
1.5 49.6 PID NECTIN PATHWAY Nectin adhesion pathway
1.5 10.5 PID ERBB4 PATHWAY ErbB4 signaling events
1.5 43.0 PID IL6 7 PATHWAY IL6-mediated signaling events
1.4 44.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
1.4 76.5 PID ATF2 PATHWAY ATF-2 transcription factor network
1.4 38.2 PID TCPTP PATHWAY Signaling events mediated by TCPTP
1.4 50.8 PID CERAMIDE PATHWAY Ceramide signaling pathway
1.4 18.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
1.3 10.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
1.0 6.8 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.9 37.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.9 56.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.8 3.9 PID S1P S1P3 PATHWAY S1P3 pathway
0.8 27.7 PID BCR 5PATHWAY BCR signaling pathway
0.7 19.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.7 14.0 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.7 19.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.6 32.3 PID BMP PATHWAY BMP receptor signaling
0.6 2.5 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.6 38.5 PID CMYB PATHWAY C-MYB transcription factor network
0.6 10.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.6 10.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.6 7.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.6 26.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.6 4.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.6 11.6 PID IL1 PATHWAY IL1-mediated signaling events
0.6 30.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.6 9.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.5 2.1 PID ALK1 PATHWAY ALK1 signaling events
0.5 2.9 PID IL3 PATHWAY IL3-mediated signaling events
0.4 12.6 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.4 19.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.4 5.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.4 13.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.4 19.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.4 5.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.4 2.3 PID ALK2 PATHWAY ALK2 signaling events
0.4 1.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.4 11.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.4 2.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.4 16.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.3 7.2 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.3 38.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 0.7 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.2 1.9 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.2 2.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 4.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.2 16.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.2 1.4 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.1 3.3 PID TNF PATHWAY TNF receptor signaling pathway
0.1 1.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 1.8 PID ARF 3PATHWAY Arf1 pathway
0.1 0.6 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 2.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 1.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 1.2 PID IL23 PATHWAY IL23-mediated signaling events
0.1 3.0 PID FOXO PATHWAY FoxO family signaling
0.0 2.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
27.8 83.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
19.5 194.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
15.2 136.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
14.2 241.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
13.4 255.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
12.4 148.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
11.9 178.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
11.7 105.0 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
11.3 202.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
11.0 143.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
10.2 295.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
9.6 115.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
8.9 168.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
8.7 183.2 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
6.8 60.9 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
6.6 256.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
6.4 6.4 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
6.3 69.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
5.8 46.5 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
5.2 67.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
5.1 50.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
4.9 791.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
4.9 44.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
4.6 41.0 REACTOME DEFENSINS Genes involved in Defensins
4.4 35.0 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
3.3 36.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
3.2 45.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
3.1 90.3 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
3.0 24.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
3.0 41.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
3.0 98.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
2.9 11.6 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
2.6 20.9 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
2.5 29.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
2.4 9.6 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
2.4 47.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
2.3 32.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
2.3 22.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
2.3 36.0 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
2.2 60.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
2.1 41.8 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
2.0 14.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
2.0 54.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
2.0 6.0 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
2.0 67.9 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
1.9 14.9 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
1.7 39.7 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
1.6 91.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
1.6 20.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
1.5 12.1 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
1.5 16.5 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
1.5 22.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
1.5 22.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
1.5 20.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
1.4 46.0 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
1.3 22.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
1.3 14.3 REACTOME BIOLOGICAL OXIDATIONS Genes involved in Biological oxidations
1.3 89.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
1.3 24.0 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
1.2 29.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
1.2 7.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
1.1 15.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
1.1 39.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
1.1 13.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
1.1 24.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
1.1 11.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
1.0 14.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
1.0 15.7 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.9 7.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.9 11.6 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.8 15.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.8 34.2 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.8 7.0 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.8 5.4 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.7 8.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.7 33.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.7 3.0 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.7 3.7 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.7 14.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.7 7.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.7 6.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.6 14.9 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.6 39.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.6 14.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.6 8.0 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.6 23.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.6 13.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.6 37.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.6 10.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.6 5.6 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.5 2.7 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.5 10.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.5 22.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.5 4.0 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.5 10.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.5 5.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.5 16.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.4 5.9 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.4 6.6 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.4 1.6 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.4 3.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.3 18.6 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.3 3.7 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.3 0.6 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.3 29.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.3 4.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.3 10.5 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.3 20.2 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.3 2.4 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.3 6.5 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.2 2.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 1.2 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.2 11.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 3.4 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.2 4.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.2 1.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.2 0.7 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.2 2.3 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.2 3.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 2.0 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.1 1.6 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.1 2.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.1 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 4.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 2.1 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 5.9 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response
0.1 0.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 2.2 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.1 3.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 4.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 0.4 REACTOME OPSINS Genes involved in Opsins
0.0 0.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.6 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.7 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling