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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Hnf1b

Z-value: 6.05

Motif logo

Transcription factors associated with Hnf1b

Gene Symbol Gene ID Gene Info
ENSRNOG00000002598 HNF1 homeobox B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hnf1brn6_v1_chr10_+_71159869_711599840.702.4e-48Click!

Activity profile of Hnf1b motif

Sorted Z-values of Hnf1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_91427575 662.96 ENSRNOT00000012092
amyloid P component, serum
chr14_-_19132208 605.47 ENSRNOT00000060535
afamin
chr14_+_20266891 572.17 ENSRNOT00000004174
group specific component
chr17_+_69588085 566.81 ENSRNOT00000064884
aldo-keto reductase family 1, member C12-like 1
chr1_+_189289957 493.73 ENSRNOT00000020587
acyl-CoA synthetase medium-chain family member 1
chr11_-_81639872 466.41 ENSRNOT00000047595
ENSRNOT00000090031
ENSRNOT00000081864
histidine-rich glycoprotein
chr17_-_69711689 451.98 ENSRNOT00000041925
aldo-keto reductase family 1, member C12
chr6_+_80188943 451.28 ENSRNOT00000059335
melanoma inhibitory activity 2
chr17_-_43543172 434.42 ENSRNOT00000080684
ENSRNOT00000029626
ENSRNOT00000082719
solute carrier family 17 member 3
chr3_+_159936856 429.68 ENSRNOT00000078703
hepatocyte nuclear factor 4, alpha
chr10_+_89285855 415.65 ENSRNOT00000028033
glucose-6-phosphatase, catalytic subunit
chr20_-_5123073 395.90 ENSRNOT00000001126
apolipoprotein M
chr10_+_89286047 387.65 ENSRNOT00000085831
glucose-6-phosphatase, catalytic subunit
chr6_+_127743971 379.31 ENSRNOT00000013045
serpin family A member 4
chr3_-_14229067 378.99 ENSRNOT00000025534
ENSRNOT00000092865
complement C5
chr1_+_88955440 378.19 ENSRNOT00000091101
proline dehydrogenase 2
chr10_+_96639924 373.90 ENSRNOT00000004756
apolipoprotein H
chr1_+_88955135 367.91 ENSRNOT00000083550
proline dehydrogenase 2
chr17_+_69634890 366.39 ENSRNOT00000029049
aldo-keto reductase family 1, member C13
chr13_-_56958549 362.48 ENSRNOT00000017293
ENSRNOT00000083912
similar to complement factor H-related protein
chr18_-_38185812 361.26 ENSRNOT00000017969
serine peptidase inhibitor, Kazal type 1-like
chr3_+_159902441 351.67 ENSRNOT00000089893
ENSRNOT00000011978
hepatocyte nuclear factor 4, alpha
chr18_-_35071619 349.12 ENSRNOT00000075695
serine protease inhibitor Kazal-type 3-like
chr1_+_263554453 347.95 ENSRNOT00000070861
ATP binding cassette subfamily C member 2
chr2_-_182035032 346.01 ENSRNOT00000009813
fibrinogen beta chain
chr2_+_182006242 344.69 ENSRNOT00000064091
fibrinogen alpha chain
chr17_-_43584152 336.00 ENSRNOT00000023241
solute carrier family 17, member 2
chr20_+_30690810 330.09 ENSRNOT00000000687
pterin-4 alpha-carbinolamine dehydratase 1
chr14_-_19191863 324.82 ENSRNOT00000003921
albumin
chr14_+_87448692 319.64 ENSRNOT00000077177
insulin-like growth factor binding protein 1
chr1_-_48563776 304.98 ENSRNOT00000023368
plasminogen
chr2_-_243407608 299.89 ENSRNOT00000014631
microsomal triglyceride transfer protein
chr13_+_56598957 298.60 ENSRNOT00000016944
ENSRNOT00000080335
ENSRNOT00000089913
coagulation factor XIII B chain
chr2_+_235264219 291.68 ENSRNOT00000086245
complement factor I
chr5_+_134492756 287.56 ENSRNOT00000012888
ENSRNOT00000057095
ENSRNOT00000051385
cytochrome P450, family 4, subfamily a, polypeptide 1
chr14_-_19159923 285.72 ENSRNOT00000003879
alpha-fetoprotein
chr11_-_66034573 282.49 ENSRNOT00000003645
homogentisate 1, 2-dioxygenase
chr5_-_126053726 282.14 ENSRNOT00000008535
proprotein convertase subtilisin/kexin type 9
chr14_-_19072677 271.46 ENSRNOT00000060548
similar to alpha-fetoprotein
chr5_-_79008363 267.24 ENSRNOT00000010040
kinesin family member 12
chr9_+_95256627 262.36 ENSRNOT00000025291
UDP glucuronosyltransferase family 1 member A5
chr1_+_250426158 260.63 ENSRNOT00000067643
APOBEC1 complementation factor
chr9_+_95295701 252.46 ENSRNOT00000025045
UDP glucuronosyltransferase family 1 member A5
chr4_+_68849033 252.27 ENSRNOT00000016912
maltase-glucoamylase
chr6_-_127508452 247.23 ENSRNOT00000073709
protein Z-dependent protease inhibitor-like
chr13_-_47377703 245.57 ENSRNOT00000005461
complement component 4 binding protein, alpha
chr3_-_127500709 244.83 ENSRNOT00000006330
hydroxyacid oxidase 1
chr2_+_23289374 242.45 ENSRNOT00000090666
ENSRNOT00000032783
dimethylglycine dehydrogenase
chr7_-_30105132 237.73 ENSRNOT00000091227
nuclear receptor subfamily 1, group H, member 4
chr20_-_27117663 235.49 ENSRNOT00000000434
phenazine biosynthesis-like protein domain containing 1
chr9_+_95161157 235.09 ENSRNOT00000071200
UDP glucuronosyltransferase family 1 member A5
chr13_-_50549981 231.95 ENSRNOT00000003918
ENSRNOT00000080486
golgi transport 1A
chr5_-_124403195 230.79 ENSRNOT00000067850
complement C8 alpha chain
chr2_-_216443518 227.92 ENSRNOT00000022496
amylase, alpha 1A
chr8_-_77398156 227.89 ENSRNOT00000091858
ENSRNOT00000085349
ENSRNOT00000082763
lipase C, hepatic type
chrX_-_32153794 223.08 ENSRNOT00000005348
transmembrane protein 27
chr1_+_189328246 221.07 ENSRNOT00000084260
acyl-CoA synthetase medium-chain family member 1
chr9_+_95274707 216.58 ENSRNOT00000045163
UDP glucuronosyltransferase family 1 member A5
chr1_+_32221636 215.97 ENSRNOT00000022346
ENSRNOT00000089941
solute carrier family 6 member 18
chr3_-_48372583 213.10 ENSRNOT00000040482
ENSRNOT00000077788
ENSRNOT00000085426
dipeptidylpeptidase 4
chr1_+_277068761 213.05 ENSRNOT00000044183
ENSRNOT00000022382
hyaluronan binding protein 2
chr1_+_261291870 213.00 ENSRNOT00000049914
4-hydroxy-2-oxoglutarate aldolase 1
chr5_+_33784715 209.79 ENSRNOT00000035685
solute carrier family 7 member 13
chr14_-_80973456 203.39 ENSRNOT00000013257
HGF activator
chr2_-_88763733 199.47 ENSRNOT00000059424
similar to solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr5_+_137356801 181.33 ENSRNOT00000027432
similar to RIKEN cDNA 2610528J11
chrX_-_110232179 180.11 ENSRNOT00000014739
serpin family A member 7
chr4_-_176381477 179.78 ENSRNOT00000048367
solute carrier organic anion transporter family, member 1a6
chr3_+_117421604 171.37 ENSRNOT00000008860
ENSRNOT00000008857
solute carrier family 12 member 1
chr6_-_26385761 170.95 ENSRNOT00000073228
glucokinase regulator
chr14_-_44613904 170.28 ENSRNOT00000003811
klotho beta
chr1_+_189514553 168.67 ENSRNOT00000020039
acyl-CoA synthetase medium-chain family member 3
chr14_+_22251499 168.18 ENSRNOT00000087991
ENSRNOT00000002705
UDP glucuronosyltransferase 2 family, polypeptide A1
chr20_-_45126062 167.95 ENSRNOT00000000720
similar to KIAA1919 protein
chr4_-_65818521 167.42 ENSRNOT00000064201
ATPase H+ transporting V0 subunit a4
chr5_+_117698764 166.54 ENSRNOT00000011486
angiopoietin-like 3
chr8_-_84320714 164.38 ENSRNOT00000079356
ENSRNOT00000088487
tubulointerstitial nephritis antigen
chr14_-_91996774 164.06 ENSRNOT00000005851
dopa decarboxylase
chr11_-_80981415 162.13 ENSRNOT00000002499
ENSRNOT00000002496
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr19_+_568287 161.44 ENSRNOT00000016419
cadherin 16
chr4_+_172119331 158.33 ENSRNOT00000010579
microsomal glutathione S-transferase 1
chr8_+_103337472 153.98 ENSRNOT00000049729
progestin and adipoQ receptor family member 9
chr1_+_107262659 151.68 ENSRNOT00000022499
growth arrest-specific 2
chr14_+_22724070 148.58 ENSRNOT00000089471
UDP glucuronosyltransferase 2 family, polypeptide B10
chr2_-_100372252 142.77 ENSRNOT00000011890
hepatocyte nuclear factor 4, gamma
chr10_-_65692016 141.39 ENSRNOT00000085074
ENSRNOT00000038690
solute carrier family 13 member 2
chr8_+_49713190 120.56 ENSRNOT00000022074
FXYD domain-containing ion transport regulator 2
chr14_+_77067503 117.25 ENSRNOT00000085275
solute carrier family 2 member 9
chr8_+_22856539 117.23 ENSRNOT00000015381
angiopoietin-like 8
chr4_-_51199570 110.98 ENSRNOT00000010788
solute carrier family 13 member 1
chr4_+_173732248 102.79 ENSRNOT00000041499
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
chr2_+_222021103 102.70 ENSRNOT00000086125
dihydropyrimidine dehydrogenase
chr2_-_158156444 102.28 ENSRNOT00000088559
ventricular zone expressed PH domain-containing 1
chr2_-_158156150 101.90 ENSRNOT00000016621
ventricular zone expressed PH domain-containing 1
chr5_+_124476168 100.80 ENSRNOT00000077754
similar to novel protein
chr17_+_69761118 98.11 ENSRNOT00000023739
aldo-keto reductase family 1, member C3
chr13_+_42008842 97.08 ENSRNOT00000038811
G protein-coupled receptor 39
chr2_-_88660449 96.63 ENSRNOT00000051741
solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr16_+_7758996 96.24 ENSRNOT00000061063
biotinidase
chr8_-_127900463 95.68 ENSRNOT00000078303
solute carrier family 22 member 13
chr7_-_68549763 94.21 ENSRNOT00000078014
solute carrier family 16 member 7
chr7_-_120518653 91.65 ENSRNOT00000016362
BAI1-associated protein 2-like 2
chr3_-_146396299 87.24 ENSRNOT00000040188
ENSRNOT00000008931
adipocyte plasma membrane associated protein
chr8_-_52937972 85.11 ENSRNOT00000007789
nicotinamide N-methyltransferase
chr7_+_29435444 83.76 ENSRNOT00000008613
solute carrier family 5 member 8
chr3_-_2453933 83.68 ENSRNOT00000014060
solute carrier family 34 member 3
chr14_+_2892753 83.66 ENSRNOT00000061630
ecotropic viral integration site 5
chr1_-_266428239 77.52 ENSRNOT00000027160
cytochrome P450, family 17, subfamily a, polypeptide 1
chr13_-_102756174 76.48 ENSRNOT00000029439
mitochondrial amidoxime reducing component 2
chr4_-_82295470 76.15 ENSRNOT00000091073
homeobox A10
chr4_-_82209933 75.48 ENSRNOT00000091106
homeobox protein Hox-A10-like
chr10_-_103848035 71.30 ENSRNOT00000029001
fatty acid desaturase 6
chr10_-_71491743 69.10 ENSRNOT00000038955
uncharacterized LOC102552988
chr2_-_166682325 68.42 ENSRNOT00000091198
ENSRNOT00000012422
serine palmitoyltransferase, small subunit B
chr15_+_104026601 66.54 ENSRNOT00000013520
ENSRNOT00000083269
ENSRNOT00000093403
claudin 10
chr1_-_87147308 65.07 ENSRNOT00000027773
ENSRNOT00000089305
ENSRNOT00000090402
actinin alpha 4
chr7_-_97071968 64.75 ENSRNOT00000006596
solute carrier family 22 (organic cation transporter), member 22
chr2_-_88553086 63.14 ENSRNOT00000042494
similar to solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr20_+_32717564 60.94 ENSRNOT00000030642
regulatory factor X, 6
chr11_-_82810014 58.07 ENSRNOT00000083539
mitogen-activated protein kinase kinase kinase 13
chr10_+_56822756 57.63 ENSRNOT00000025372
solute carrier family 16, member 11
chr19_-_39267928 56.06 ENSRNOT00000027686
transmembrane p24 trafficking protein 6
chr15_+_56756661 55.90 ENSRNOT00000013324
esterase D
chr5_+_138685624 54.14 ENSRNOT00000011867
guanylate cyclase activator 2A
chr1_-_15374850 51.53 ENSRNOT00000016728
peroxisomal biogenesis factor 7
chr13_+_47454591 51.17 ENSRNOT00000005791
similar to specifically androgen-regulated protein
chr5_-_131860637 50.33 ENSRNOT00000064569
ENSRNOT00000080242
solute carrier family 5 member 9
chr5_-_158439078 49.69 ENSRNOT00000025517
kelch domain containing 7A
chr4_-_149988295 49.45 ENSRNOT00000019649
FXYD domain-containing ion transport regulator 4
chr13_-_53870428 48.25 ENSRNOT00000000812
nuclear receptor subfamily 5, group A, member 2
chr9_-_42839837 47.86 ENSRNOT00000038610
neuralized E3 ubiquitin protein ligase 3
chr5_+_157416897 46.81 ENSRNOT00000023358
ring finger protein 186
chr14_+_80195715 44.03 ENSRNOT00000010784
SH3 domain and tetratricopeptide repeats 1
chr5_-_138697641 42.48 ENSRNOT00000012062
guanylate cyclase activator 2B
chr8_-_127912860 39.81 ENSRNOT00000040498
similar to solute carrier family 22 (organic cation transporter), member 13
chr4_-_120559078 39.68 ENSRNOT00000085730
ENSRNOT00000079575
kelch repeat and BTB domain containing 12
chr9_-_88356716 37.54 ENSRNOT00000077503
collagen type IV alpha 4 chain
chr1_+_83965608 36.43 ENSRNOT00000079995
cytochrome P450, family 2, subfamily t, polypeptide 1
chr7_+_76059386 36.39 ENSRNOT00000009337
grainyhead-like transcription factor 2
chr1_-_101095594 34.23 ENSRNOT00000027944
Fc fragment of IgG receptor and transporter
chr11_+_77644541 31.59 ENSRNOT00000074688
transmembrane protein 207
chr16_-_75179089 31.47 ENSRNOT00000058061
defensin beta 9
chr7_-_120077612 30.77 ENSRNOT00000011750
galectin 2
chr6_-_142418779 26.39 ENSRNOT00000072280
ENSRNOT00000065808

chr4_-_155051429 26.32 ENSRNOT00000020094
killer cell lectin like receptor G1
chr7_-_98270110 24.59 ENSRNOT00000064847
annexin A13
chr2_+_185846232 24.38 ENSRNOT00000023418
LPS responsive beige-like anchor protein
chr7_-_140291620 24.20 ENSRNOT00000088323
adenylate cyclase 6
chr1_+_31124825 24.13 ENSRNOT00000092105

chr1_-_53802658 24.12 ENSRNOT00000032667
afadin, adherens junction formation factor
chr4_-_30380119 23.38 ENSRNOT00000036460
paraoxonase 2
chr9_-_92524739 23.31 ENSRNOT00000089889
solute carrier family 16, member 14
chr17_-_10004321 22.96 ENSRNOT00000042394
fibroblast growth factor receptor 4
chr10_-_13446135 22.14 ENSRNOT00000084991
potassium channel tetramerization domain containing 5
chr1_-_199341302 21.48 ENSRNOT00000073596
vitamin K epoxide reductase complex, subunit 1
chr3_-_9807328 19.80 ENSRNOT00000064660
torsin family 1, member A
chr13_+_90514336 19.07 ENSRNOT00000088996
ENSRNOT00000085377
peroxisomal biogenesis factor 19
chr16_+_29674793 17.88 ENSRNOT00000059724
annexin A10
chr4_+_78263866 17.05 ENSRNOT00000033807
expressed sequence AI854703
chr11_+_81796891 16.74 ENSRNOT00000058402
crystallin, gamma S
chr3_+_103597194 16.22 ENSRNOT00000073004
similar to olfactory receptor 1318
chr5_+_116420690 15.92 ENSRNOT00000087089
nuclear factor I/A
chr6_-_44363915 15.48 ENSRNOT00000085925
inhibitor of DNA binding 2, HLH protein
chr17_+_77167740 15.24 ENSRNOT00000042881
optineurin
chrX_+_33443186 14.33 ENSRNOT00000005622
S100 calcium binding protein G
chr7_-_3707226 13.53 ENSRNOT00000064380
olfactory receptor 879
chr4_+_156324922 12.94 ENSRNOT00000039463
vomeronasal 2 receptor, 48
chr1_-_172395872 12.83 ENSRNOT00000055174
olfactory receptor 252
chr1_+_164705604 11.75 ENSRNOT00000051450
ENSRNOT00000071384
olfactory receptor 36
chr1_-_172567846 10.96 ENSRNOT00000012974
olfactory receptor 259
chr3_-_167759273 10.03 ENSRNOT00000049457

chr1_-_101819478 9.55 ENSRNOT00000056181
glutamate-rich WD repeat containing 1
chr11_+_18454144 9.27 ENSRNOT00000072550

chr15_-_55277713 9.12 ENSRNOT00000023037
integral membrane protein 2B
chr6_-_142385773 8.93 ENSRNOT00000071555

chr1_-_167893061 8.60 ENSRNOT00000049401
olfactory receptor 60
chr2_+_149843282 8.30 ENSRNOT00000074805
similar to hypothetical protein C130079G13
chr7_-_50034932 8.17 ENSRNOT00000081885
protein tyrosine phosphatase, receptor type, Q
chr11_+_28724341 7.62 ENSRNOT00000049858
RIKEN cDNA 2310034C09-like
chr3_-_103301388 7.58 ENSRNOT00000046162
olfactory receptor 788
chr8_+_73682887 7.56 ENSRNOT00000057522
vacuolar protein sorting 13C
chr15_+_35685009 7.53 ENSRNOT00000085764
olfactory receptor 144-like
chr18_-_71614980 7.42 ENSRNOT00000032563
peroxisomal biogenesis factor 19-like
chr7_-_9427506 7.36 ENSRNOT00000041565
olfactory receptor 1068
chr5_-_16995304 7.22 ENSRNOT00000061780
short chain dehydrogenase/reductase family 16C, member 6
chr8_-_19586811 7.12 ENSRNOT00000091744
olfactory receptor 1149
chr11_-_23058456 7.03 ENSRNOT00000073285
olfactory receptor 6C6-like
chr4_+_72388568 6.97 ENSRNOT00000038359
olfactory receptor 809
chr4_+_166222451 6.30 ENSRNOT00000045884
proline-rich protein 15
chr18_-_31749647 5.81 ENSRNOT00000044287
nuclear receptor subfamily 3, group C, member 1
chr16_+_2634603 5.80 ENSRNOT00000019113
HESX homeobox 1
chr4_+_166211646 5.58 ENSRNOT00000007139
ENSRNOT00000007119
proline-rich protein 15
chr1_+_168390615 5.23 ENSRNOT00000039822
olfactory receptor 87
chr10_+_111770168 4.29 ENSRNOT00000074598
vomeronasal 2 receptor, 65
chr1_+_168326922 4.28 ENSRNOT00000046793
olfactory receptor 83
chr7_+_6215743 4.10 ENSRNOT00000050967
olfactory receptor 1002
chr3_-_78974631 4.07 ENSRNOT00000087245
olfactory receptor 733
chr10_+_112056994 4.03 ENSRNOT00000073032
vomeronasal 2 receptor, 65
chr15_+_39638510 3.80 ENSRNOT00000037800
RCC1 and BTB domain containing protein 1
chr17_+_42695322 3.77 ENSRNOT00000073558

Network of associatons between targets according to the STRING database.

First level regulatory network of Hnf1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
248.7 746.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
244.8 244.8 GO:0009441 glycolate metabolic process(GO:0009441)
195.3 781.3 GO:0042977 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
165.7 663.0 GO:0052422 modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422) regulation of exo-alpha-sialidase activity(GO:1903015)
155.5 466.4 GO:0097037 heme export(GO:0097037)
138.1 690.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
132.0 395.9 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
107.4 966.5 GO:0052697 xenobiotic glucuronidation(GO:0052697)
101.8 305.4 GO:0010034 response to acetate(GO:0010034)
101.7 305.0 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
93.5 373.9 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
87.0 348.0 GO:0050787 detoxification of mercury ion(GO:0050787)
81.9 245.6 GO:0045959 negative regulation of complement activation, classical pathway(GO:0045959)
80.8 242.4 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
80.3 803.3 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
79.2 237.7 GO:0034971 histone H3-R17 methylation(GO:0034971)
78.5 235.5 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
75.2 451.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
71.9 287.6 GO:0048252 lauric acid metabolic process(GO:0048252)
71.0 213.1 GO:0061744 motor behavior(GO:0061744)
70.5 282.1 GO:0032805 positive regulation of low-density lipoprotein particle receptor catabolic process(GO:0032805)
65.2 260.6 GO:0016554 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) cytidine to uridine editing(GO:0016554)
63.2 379.0 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
61.3 612.6 GO:0006558 L-phenylalanine metabolic process(GO:0006558) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221)
57.1 171.4 GO:0032978 protein insertion into membrane from inner side(GO:0032978)
54.1 324.8 GO:0001907 killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004) response to platinum ion(GO:0070541)
54.0 162.1 GO:1990743 protein sialylation(GO:1990743)
53.3 213.1 GO:1904975 response to bleomycin(GO:1904975)
53.2 213.0 GO:0009436 glyoxylate catabolic process(GO:0009436)
50.2 854.1 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
42.8 299.9 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
42.0 168.2 GO:0052695 cellular glucuronidation(GO:0052695)
41.0 164.1 GO:0052314 phytoalexin metabolic process(GO:0052314)
36.8 699.5 GO:1902572 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
34.2 102.7 GO:0006214 thymidine catabolic process(GO:0006214) pyrimidine deoxyribonucleoside catabolic process(GO:0046127)
34.2 171.0 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) negative regulation of glucokinase activity(GO:0033132) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594) negative regulation of hexokinase activity(GO:1903300)
34.1 170.3 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
33.3 166.5 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
32.7 98.1 GO:0019747 response to jasmonic acid(GO:0009753) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of isoprenoid metabolic process(GO:0019747) cellular response to jasmonic acid stimulus(GO:0071395)
32.4 97.1 GO:0035483 gastric emptying(GO:0035483)
29.8 595.1 GO:0042359 vitamin D metabolic process(GO:0042359)
24.8 223.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
22.0 285.7 GO:0042448 progesterone metabolic process(GO:0042448)
19.1 76.5 GO:0042126 nitrate metabolic process(GO:0042126)
18.8 94.2 GO:1901475 pyruvate transmembrane transport(GO:1901475)
18.0 180.1 GO:0070327 thyroid hormone transport(GO:0070327)
17.1 68.4 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
16.2 64.8 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
15.1 605.5 GO:0051180 vitamin transport(GO:0051180)
14.1 297.0 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
13.0 65.1 GO:0048549 positive regulation of pinocytosis(GO:0048549)
12.9 167.4 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
12.3 491.1 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
11.3 135.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
10.7 117.3 GO:0046415 urate metabolic process(GO:0046415)
10.4 522.5 GO:0006956 complement activation(GO:0006956)
10.4 291.5 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
10.3 883.5 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
9.9 158.3 GO:0071447 cellular response to hydroperoxide(GO:0071447)
9.7 48.3 GO:0061113 pancreas morphogenesis(GO:0061113)
9.6 48.0 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
9.3 55.9 GO:0046292 formaldehyde metabolic process(GO:0046292)
9.1 36.4 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
8.8 96.6 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
7.1 120.6 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
6.9 111.0 GO:1902358 sulfate transmembrane transport(GO:1902358)
6.5 123.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
6.1 91.7 GO:0051764 actin crosslink formation(GO:0051764)
6.1 60.9 GO:0003310 pancreatic A cell differentiation(GO:0003310)
5.7 102.8 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
5.4 21.5 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
5.3 85.1 GO:0001887 selenium compound metabolic process(GO:0001887)
5.2 15.5 GO:0001966 thigmotaxis(GO:0001966)
5.0 216.0 GO:0006972 hyperosmotic response(GO:0006972)
4.8 24.1 GO:0034334 adherens junction maintenance(GO:0034334)
4.0 24.2 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660)
3.8 19.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
3.3 19.8 GO:0051584 regulation of dopamine uptake involved in synaptic transmission(GO:0051584) regulation of catecholamine uptake involved in synaptic transmission(GO:0051940)
3.0 96.2 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
2.9 37.5 GO:0032836 glomerular basement membrane development(GO:0032836)
2.6 34.2 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
2.6 481.9 GO:0007596 blood coagulation(GO:0007596)
2.3 22.8 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
2.3 9.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
2.2 76.1 GO:0060065 uterus development(GO:0060065)
2.1 100.8 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
1.6 15.9 GO:0072189 ureter development(GO:0072189)
1.6 379.3 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
1.5 252.7 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
1.5 5.8 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
1.4 83.7 GO:0031338 regulation of vesicle fusion(GO:0031338)
1.3 36.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
1.2 1147.5 GO:0055114 oxidation-reduction process(GO:0055114)
1.1 49.4 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
1.0 5.8 GO:0030916 otic vesicle formation(GO:0030916)
0.9 9.5 GO:0006337 nucleosome disassembly(GO:0006337)
0.7 141.4 GO:0098656 anion transmembrane transport(GO:0098656)
0.5 32.9 GO:0000186 activation of MAPKK activity(GO:0000186)
0.4 8.2 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.4 103.3 GO:0007018 microtubule-based movement(GO:0007018)
0.4 2.8 GO:0042976 activation of Janus kinase activity(GO:0042976)
0.3 72.8 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.2 2.7 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 2.2 GO:0070166 enamel mineralization(GO:0070166)
0.1 23.4 GO:0009636 response to toxic substance(GO:0009636)
0.1 22.1 GO:0051260 protein homooligomerization(GO:0051260)
0.1 44.7 GO:0005975 carbohydrate metabolic process(GO:0005975)
0.1 3.4 GO:0050909 sensory perception of taste(GO:0050909)
0.0 3.4 GO:0007601 visual perception(GO:0007601)
0.0 3.0 GO:0030326 embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113)
0.0 1.2 GO:0060038 cardiac muscle cell proliferation(GO:0060038)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
116.6 466.4 GO:0061474 phagolysosome membrane(GO:0061474)
101.7 305.0 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
87.1 609.8 GO:0005579 membrane attack complex(GO:0005579)
86.3 690.7 GO:0005577 fibrinogen complex(GO:0005577)
79.2 395.9 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
49.1 245.6 GO:0043159 acrosomal matrix(GO:0043159)
43.2 561.0 GO:0046581 intercellular canaliculus(GO:0046581)
41.5 373.9 GO:0042627 chylomicron(GO:0042627)
37.2 260.6 GO:0045293 mRNA editing complex(GO:0045293)
33.5 167.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
27.3 3109.3 GO:0072562 blood microparticle(GO:0072562)
23.1 439.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
18.0 162.1 GO:0000138 Golgi trans cisterna(GO:0000138)
16.3 227.9 GO:0034364 high-density lipoprotein particle(GO:0034364)
13.0 324.1 GO:0031528 microvillus membrane(GO:0031528)
10.0 120.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
9.2 91.7 GO:0071439 clathrin complex(GO:0071439)
8.6 68.4 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
7.4 237.7 GO:0005719 nuclear euchromatin(GO:0005719)
7.2 282.1 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
5.9 65.1 GO:0031143 pseudopodium(GO:0031143)
5.8 741.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
5.7 439.8 GO:0031526 brush border membrane(GO:0031526)
5.0 699.5 GO:0001669 acrosomal vesicle(GO:0001669)
4.9 102.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
4.7 37.5 GO:0098642 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
4.5 58.1 GO:0008385 IkappaB kinase complex(GO:0008385)
4.0 19.8 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
3.9 267.2 GO:0005871 kinesin complex(GO:0005871)
3.2 538.6 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
2.0 2645.4 GO:0005615 extracellular space(GO:0005615)
1.9 632.3 GO:0016324 apical plasma membrane(GO:0016324)
1.8 689.9 GO:0005667 transcription factor complex(GO:0005667)
1.6 380.8 GO:0005759 mitochondrial matrix(GO:0005759)
1.6 700.4 GO:0005743 mitochondrial inner membrane(GO:0005743)
1.2 39.1 GO:0001772 immunological synapse(GO:0001772)
1.0 71.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.9 2.7 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.9 1842.8 GO:0070062 extracellular exosome(GO:0070062)
0.8 419.2 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.6 548.6 GO:0005887 integral component of plasma membrane(GO:0005887)
0.5 24.1 GO:0043296 apical junction complex(GO:0043296)
0.4 193.6 GO:0005576 extracellular region(GO:0005576)
0.3 15.2 GO:0005776 autophagosome(GO:0005776)
0.3 8.2 GO:0032421 stereocilium bundle(GO:0032421)
0.3 212.3 GO:0005739 mitochondrion(GO:0005739)
0.1 536.8 GO:0016021 integral component of membrane(GO:0016021)
0.1 24.4 GO:0000323 lytic vacuole(GO:0000323) lysosome(GO:0005764)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
248.7 746.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
160.7 803.3 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
126.3 379.0 GO:0031714 C5a anaphylatoxin chemotactic receptor binding(GO:0031714)
124.6 373.9 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
120.0 480.2 GO:0016160 amylase activity(GO:0016160)
110.4 883.5 GO:0003996 acyl-CoA ligase activity(GO:0003996)
110.0 330.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
97.8 586.5 GO:0005499 vitamin D binding(GO:0005499)
94.7 663.0 GO:0001849 complement component C1q binding(GO:0001849)
79.2 237.7 GO:0038181 bile acid receptor activity(GO:0038181)
75.2 451.3 GO:0042954 lipoprotein transporter activity(GO:0042954)
71.9 287.6 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
71.2 854.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
65.1 781.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
61.2 244.8 GO:0003973 (S)-2-hydroxy-acid oxidase activity(GO:0003973)
57.1 171.4 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
55.8 223.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
54.7 164.1 GO:0004058 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
53.2 213.0 GO:0016833 oxo-acid-lyase activity(GO:0016833)
53.1 1114.9 GO:0034185 apolipoprotein binding(GO:0034185)
40.5 162.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
40.1 1242.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
39.7 476.4 GO:0001848 complement binding(GO:0001848)
35.5 319.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
34.2 102.7 GO:0017113 dihydrouracil dehydrogenase (NAD+) activity(GO:0004159) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
32.7 98.1 GO:0045550 geranylgeranyl reductase activity(GO:0045550) delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
32.1 96.2 GO:0047708 biotinidase activity(GO:0047708)
28.4 85.1 GO:0098603 selenol Se-methyltransferase activity(GO:0098603)
25.0 200.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
24.4 171.0 GO:0070095 fructose-6-phosphate binding(GO:0070095)
22.5 180.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
21.8 435.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
21.3 213.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
19.1 76.5 GO:0008940 nitrate reductase activity(GO:0008940)
18.8 94.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
18.5 166.5 GO:0004859 phospholipase inhibitor activity(GO:0004859)
17.1 324.8 GO:0015643 toxic substance binding(GO:0015643)
16.2 242.4 GO:0005542 folic acid binding(GO:0005542)
15.8 110.6 GO:0004064 arylesterase activity(GO:0004064)
14.7 117.3 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
13.8 96.6 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
13.7 68.4 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
12.8 102.8 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
11.7 1326.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
10.1 70.6 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
9.3 120.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
9.1 209.2 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
8.8 158.3 GO:0043295 glutathione binding(GO:0043295)
8.6 605.5 GO:0019842 vitamin binding(GO:0019842)
8.0 167.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
7.3 389.4 GO:0005044 scavenger receptor activity(GO:0005044)
7.2 21.5 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
6.9 111.0 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
6.8 34.2 GO:0019770 IgG receptor activity(GO:0019770)
6.4 193.2 GO:0017134 fibroblast growth factor binding(GO:0017134)
6.4 514.8 GO:0015297 antiporter activity(GO:0015297)
6.2 166.7 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
5.5 77.5 GO:0016832 aldehyde-lyase activity(GO:0016832)
5.1 667.5 GO:0030674 protein binding, bridging(GO:0030674)
4.8 395.9 GO:0016209 antioxidant activity(GO:0016209)
4.0 24.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
3.8 30.8 GO:0016936 galactoside binding(GO:0016936)
3.5 24.6 GO:1901611 phosphatidylglycerol binding(GO:1901611)
3.4 287.2 GO:0003707 steroid hormone receptor activity(GO:0003707)
3.1 260.6 GO:0003725 double-stranded RNA binding(GO:0003725)
3.0 267.2 GO:0003777 microtubule motor activity(GO:0003777)
3.0 36.4 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
3.0 344.4 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
2.7 65.1 GO:0042974 retinoic acid receptor binding(GO:0042974)
2.2 58.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
2.1 36.4 GO:0019825 oxygen binding(GO:0019825)
2.1 1381.7 GO:0016491 oxidoreductase activity(GO:0016491)
1.9 401.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
1.8 55.9 GO:0016790 thiolester hydrolase activity(GO:0016790)
1.6 19.8 GO:0051787 misfolded protein binding(GO:0051787)
1.3 22.1 GO:0097602 cullin family protein binding(GO:0097602)
1.2 172.5 GO:0016853 isomerase activity(GO:0016853)
0.8 16.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.7 2.2 GO:0046848 hydroxyapatite binding(GO:0046848)
0.7 111.6 GO:0005179 hormone activity(GO:0005179)
0.7 9.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.7 52.1 GO:0051117 ATPase binding(GO:0051117)
0.6 37.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.3 37.3 GO:0042826 histone deacetylase binding(GO:0042826)
0.3 9.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.3 3.4 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.1 15.5 GO:0044325 ion channel binding(GO:0044325)
0.1 21.9 GO:0008017 microtubule binding(GO:0008017)
0.1 24.1 GO:0045296 cadherin binding(GO:0045296)
0.0 18.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 5.8 GO:0008022 protein C-terminus binding(GO:0008022)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
45.8 2520.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
22.3 690.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
11.5 379.3 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
7.4 305.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
6.6 245.6 PID CD40 PATHWAY CD40/CD40L signaling
4.7 1091.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
4.0 174.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
3.3 193.2 PID FGF PATHWAY FGF signaling pathway
3.3 102.8 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
2.5 76.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
2.3 160.4 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
1.6 58.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
1.3 24.2 PID LPA4 PATHWAY LPA4-mediated signaling events
1.1 51.8 PID AURORA B PATHWAY Aurora B signaling
0.7 136.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.6 26.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.6 19.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.4 15.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.4 18.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.3 30.1 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.3 15.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 53.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 3.4 PID CONE PATHWAY Visual signal transduction: Cones

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
72.9 437.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
67.5 1283.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
61.8 989.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
41.3 537.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
34.2 924.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
32.5 324.8 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
31.2 624.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
31.0 527.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
29.0 609.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
24.8 346.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
21.6 974.2 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
19.7 649.7 REACTOME STEROID HORMONES Genes involved in Steroid hormones
17.8 213.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
15.2 958.2 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
13.5 538.6 REACTOME AMYLOIDS Genes involved in Amyloids
13.0 117.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
10.9 164.1 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
10.8 162.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
9.8 363.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
7.9 102.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
7.4 193.2 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
7.2 166.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
6.4 167.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
6.1 531.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
5.6 151.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
4.7 837.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
4.4 48.3 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
4.1 77.9 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
3.6 21.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
3.0 315.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
2.0 66.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
1.6 24.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
1.6 75.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
1.0 156.4 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.4 20.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.3 97.1 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.2 5.8 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression