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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Hlx

Z-value: 0.16

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Transcription factors associated with Hlx

Gene Symbol Gene ID Gene Info
ENSRNOG00000002309 H2.0-like homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hlxrn6_v1_chr13_-_102643223_102643223-0.072.3e-01Click!

Activity profile of Hlx motif

Sorted Z-values of Hlx motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_264975132 3.75 ENSRNOT00000021748
ladybird homeobox 1
chr4_-_180234804 3.39 ENSRNOT00000070957
basic helix-loop-helix family, member e41
chr4_+_33638709 1.50 ENSRNOT00000009888
ENSRNOT00000034719
ENSRNOT00000052333
tachykinin, precursor 1
chr8_+_5790034 1.06 ENSRNOT00000061887
matrix metallopeptidase 27
chr4_+_57925323 0.91 ENSRNOT00000085798
carboxypeptidase A5
chrX_-_115175299 0.89 ENSRNOT00000074322
doublecortin
chr14_+_23405717 0.87 ENSRNOT00000029805
transmembrane protease, serine 11C
chr1_-_166912524 0.70 ENSRNOT00000092952
inositol polyphosphate phosphatase-like 1
chr1_-_101819478 0.57 ENSRNOT00000056181
glutamate-rich WD repeat containing 1
chr3_-_90751055 0.38 ENSRNOT00000040741
LRRGT00091
chr17_+_52938980 0.16 ENSRNOT00000081052
GA binding protein transcription factor, beta subunit 1-like
chr1_-_101095594 0.02 ENSRNOT00000027944
Fc fragment of IgG receptor and transporter

Network of associatons between targets according to the STRING database.

First level regulatory network of Hlx

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.7 GO:0048664 neuron fate determination(GO:0048664)
0.3 3.4 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.3 1.5 GO:2000851 positive regulation of saliva secretion(GO:0046878) positive regulation of glucocorticoid secretion(GO:2000851)
0.1 0.9 GO:0097264 self proteolysis(GO:0097264)
0.1 0.7 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.9 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.6 GO:0006337 nucleosome disassembly(GO:0006337)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.4 GO:0043426 MRF binding(GO:0043426)
0.1 0.7 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.7 PID EPHA2 FWD PATHWAY EPHA2 forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane