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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Hcfc1_Six5_Smarcc2_Zfp143

Z-value: 2.43

Motif logo

Transcription factors associated with Hcfc1_Six5_Smarcc2_Zfp143

Gene Symbol Gene ID Gene Info
ENSRNOG00000051948 host cell factor C1
ENSRNOG00000060146 SIX homeobox 5
ENSRNOG00000031135 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
ENSRNOG00000010087 zinc finger protein 143

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hcfc1rn6_v1_chrX_+_156812064_1568120640.383.8e-12Click!
Zfp143rn6_v1_chr1_+_174702373_1747023730.261.7e-06Click!
Smarcc2rn6_v1_chr7_+_2875909_28759090.241.0e-05Click!
Six5rn6_v1_chr1_+_80000165_80000165-0.044.6e-01Click!

Activity profile of Hcfc1_Six5_Smarcc2_Zfp143 motif

Sorted Z-values of Hcfc1_Six5_Smarcc2_Zfp143 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_143063983 37.15 ENSRNOT00000006329
NSF attachment protein beta
chr4_-_61573003 32.83 ENSRNOT00000012179
solute carrier family 35 member B4
chr14_-_80169431 31.32 ENSRNOT00000079769
ENSRNOT00000058315
actin binding LIM protein family, member 2
chr15_-_4454958 29.91 ENSRNOT00000070933
nudix hydrolase 13
chr1_-_226255886 28.30 ENSRNOT00000027842
flap structure-specific endonuclease 1
chr7_+_117417687 27.28 ENSRNOT00000018240
MAF1 homolog, negative regulator of RNA polymerase III
chr11_+_84396033 26.67 ENSRNOT00000002316
ATP binding cassette subfamily C member 5
chr7_-_12429897 23.80 ENSRNOT00000020670
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr6_+_99883959 23.09 ENSRNOT00000010588
farnesyltransferase, CAAX box, beta
chr16_+_36116258 22.40 ENSRNOT00000017652
Sin3A associated protein 30
chr5_+_165922915 21.83 ENSRNOT00000089179
ENSRNOT00000059522
DNA fragmentation factor subunit alpha
chr11_+_47146308 21.79 ENSRNOT00000002191
centrosomal protein 97
chr2_-_41785792 21.09 ENSRNOT00000015871
RAB3C, member RAS oncogene family
chr2_-_187258140 20.86 ENSRNOT00000017735
papillary renal cell carcinoma (translocation-associated)
chr5_+_135663371 19.79 ENSRNOT00000024375
mutY DNA glycosylase
chr7_-_145450233 19.69 ENSRNOT00000092974
ENSRNOT00000021523
calcium binding and coiled coil domain 1
chr10_+_98706960 19.67 ENSRNOT00000006217
mitogen-activated protein kinase kinase 6
chr4_+_118655728 19.36 ENSRNOT00000043082
AP2 associated kinase 1
chr1_+_220307394 19.36 ENSRNOT00000071891
equilibrative nucleoside transporter 2
chr2_+_188495629 18.99 ENSRNOT00000027828
family with sequence similarity 189, member B
chr14_-_84937725 18.96 ENSRNOT00000083839
ubiquinol-cytochrome c reductase, complex III subunit X
chr1_-_82108083 18.75 ENSRNOT00000027677
ENSRNOT00000084530
glycogen synthase kinase 3 alpha
chr7_-_144322240 18.72 ENSRNOT00000089290
calcium-binding and coiled-coil domain-containing protein 1-like
chr12_+_7454884 18.42 ENSRNOT00000077328
katanin p60 ATPase-containing subunit A-like 1-like
chr1_+_220400855 18.35 ENSRNOT00000027178
solute carrier family 29 member 2
chr12_+_23789638 17.97 ENSRNOT00000001954
ENSRNOT00000084730
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
chr4_+_7282948 17.84 ENSRNOT00000011052
cyclin-dependent kinase 5
chr3_+_148327965 17.74 ENSRNOT00000010851
ENSRNOT00000088481
TPX2, microtubule nucleation factor
chr6_+_129835919 17.50 ENSRNOT00000036035
vaccinia related kinase 1
chr8_+_28045288 17.45 ENSRNOT00000085997
thymocyte nuclear protein 1
chr5_+_173542358 17.39 ENSRNOT00000027347
similar to RIKEN cDNA 9430015G10
chr3_+_8363937 17.35 ENSRNOT00000019500
solute carrier family 27 member 4
chr1_+_81373340 17.23 ENSRNOT00000026814
zinc finger protein 428
chr4_+_28441301 17.10 ENSRNOT00000067087
VPS50 EARP/GARPII complex subunit
chr3_+_110367939 16.71 ENSRNOT00000010406
BUB1 mitotic checkpoint serine/threonine kinase B
chr10_-_12994495 16.60 ENSRNOT00000004672
THO complex 6
chr2_+_174013288 16.42 ENSRNOT00000013904
serpin family I member 1
chr3_-_55951584 16.31 ENSRNOT00000036585
FAST kinase domains 1
chr8_+_28045093 16.23 ENSRNOT00000073373
thymocyte nuclear protein 1
chr7_+_11660934 16.12 ENSRNOT00000022336
lamin B2
chr1_+_75356220 15.95 ENSRNOT00000019799
DNA ligase 1
chr14_-_106393670 15.61 ENSRNOT00000011429
malate dehydrogenase 1
chr9_-_93607087 15.55 ENSRNOT00000025262
phosphodiesterase 6D
chr5_+_135562034 15.50 ENSRNOT00000056967
coiled-coil domain containing 163
chr18_-_81807627 14.99 ENSRNOT00000020376
translocase of inner mitochondrial membrane 21
chr9_+_60883981 14.98 ENSRNOT00000081002
coiled-coil domain containing 150
chr12_-_25638797 14.82 ENSRNOT00000002033
GATS protein-like 2
chr18_-_28495937 14.74 ENSRNOT00000027194
DnaJ heat shock protein family (Hsp40) member C18
chr10_+_16259728 14.73 ENSRNOT00000028115
biorientation of chromosomes in cell division 1
chr20_-_46666830 14.61 ENSRNOT00000000331
centrosomal protein 57-like 1
chr5_-_135561914 14.43 ENSRNOT00000023178
methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
chr5_+_78267248 14.29 ENSRNOT00000019910
pre-mRNA processing factor 4
chr4_-_7311807 14.28 ENSRNOT00000012222
ENSRNOT00000089817
ATP binding cassette subfamily B member 8
chr20_+_18547370 14.08 ENSRNOT00000000750
ubiquitin-conjugating enzyme E2D 1
chr7_-_83348487 13.94 ENSRNOT00000006685
NudC domain containing 1
chr4_-_60358562 13.93 ENSRNOT00000018001
coiled-coil-helix-coiled-coil-helix domain containing 3
chr11_+_88831130 13.48 ENSRNOT00000002478
dynamin 1-like
chr14_+_81725513 13.40 ENSRNOT00000020154
zinc finger FYVE-type containing 28
chr10_-_51669297 13.37 ENSRNOT00000071595
Rho GTPase activating protein 44
chr11_+_88830957 13.32 ENSRNOT00000002482
ENSRNOT00000002477
dynamin 1-like
chr10_+_10967658 13.23 ENSRNOT00000004999
cell death-inducing p53 target 1
chr2_+_93518806 13.20 ENSRNOT00000050987
sorting nexin 16
chr4_+_123118468 12.99 ENSRNOT00000010895
transmembrane protein 43
chr2_+_187893368 12.81 ENSRNOT00000092031
mex-3 RNA binding family member A
chr20_-_48503898 12.77 ENSRNOT00000073091
WAS protein family, member 1
chr3_+_11114551 12.73 ENSRNOT00000013507
phospholipid phosphatase 7
chr1_+_100473643 12.52 ENSRNOT00000026379
Josephin domain containing 2
chr11_+_32450587 12.47 ENSRNOT00000061235
small integral membrane protein 11
chr8_-_62332115 12.19 ENSRNOT00000025783
mannose phosphate isomerase (mapped)
chr9_+_93607477 12.14 ENSRNOT00000025411
COP9 signalosome subunit 7B
chr2_+_54897424 12.02 ENSRNOT00000017665
tetratricopeptide repeat domain 33
chr4_-_157347803 11.92 ENSRNOT00000020785
ubiquitin specific peptidase 5
chr1_+_142679345 11.71 ENSRNOT00000034267
zinc finger and SCAN domain containing 2
chr1_-_266142538 11.68 ENSRNOT00000026792
ARP1 actin-related protein 1 homolog A, centractin alpha
chr5_+_152681101 11.57 ENSRNOT00000076052
ENSRNOT00000022574
stathmin 1
chr1_-_84491466 11.56 ENSRNOT00000034609
mitogen activated protein kinase kinase kinase 10
chr3_-_177078594 11.54 ENSRNOT00000020695
uridine-cytidine kinase 1-like 1
chr7_+_143897014 11.53 ENSRNOT00000017314
extra spindle pole bodies like 1, separase
chr19_-_22632071 11.39 ENSRNOT00000077275
glutamic--pyruvic transaminase 2
chr4_-_119568736 11.01 ENSRNOT00000041234
aprataxin and PNKP like factor
chr4_-_123118186 10.98 ENSRNOT00000038096
coiled-coil-helix-coiled-coil-helix domain containing 4
chr2_-_211001258 10.72 ENSRNOT00000037336
ataxin 7-like 2
chr8_-_61823102 10.60 ENSRNOT00000058645
nei-like DNA glycosylase 1
chr1_-_63293635 10.59 ENSRNOT00000090337
zinc finger protein interacting with K protein 1
chr3_+_110918243 10.50 ENSRNOT00000056432
RAD51 recombinase
chr2_-_58534211 10.48 ENSRNOT00000089178
S-phase kinase associated protein 2
chr6_+_26546924 10.48 ENSRNOT00000007763
eukaryotic translation initiation factor 2B subunit delta
chr17_-_54070399 10.43 ENSRNOT00000022924
beta-1,3-N-acetylgalactosaminyltransferase 2
chr5_-_1347921 10.42 ENSRNOT00000007994
ganglioside-induced differentiation-associated-protein 1
chr1_-_71399751 10.31 ENSRNOT00000020787
zinc finger protein 444
chr20_+_45458558 10.17 ENSRNOT00000000713
cyclin-dependent kinase 19
chr19_+_54766589 10.15 ENSRNOT00000025894
Btg3 associated nuclear protein
chr5_-_136748980 10.09 ENSRNOT00000026844
importin 13
chr8_+_116297950 10.01 ENSRNOT00000051522
NPR2-like, GATOR1 complex subunit
chr5_-_138222534 9.97 ENSRNOT00000009691
zinc finger protein 691
chr11_+_61748883 9.97 ENSRNOT00000093552
queuine tRNA-ribosyltransferase accessory subunit 2
chr10_-_104179523 9.87 ENSRNOT00000005292
solute carrier family 25 member 19
chr17_-_54070231 9.84 ENSRNOT00000085150
beta-1,3-N-acetylgalactosaminyltransferase 2
chr16_+_81587446 9.80 ENSRNOT00000092680
DCN1, defective in cullin neddylation 1, domain containing 2
chr10_+_39655455 9.70 ENSRNOT00000058817
acyl-CoA synthetase long-chain family member 6
chr2_+_187288644 9.65 ENSRNOT00000035271
mitochondrial ribosomal protein L24
chr4_+_57050214 9.64 ENSRNOT00000025165
adenosylhomocysteinase-like 2
chr7_-_2986935 9.63 ENSRNOT00000081125
ENSRNOT00000006578
proliferation-associated 2G4
chr10_-_49196177 9.52 ENSRNOT00000084418
zinc finger protein 286A
chr1_-_68269117 9.52 ENSRNOT00000072367
zinc finger protein interacting with ribonucleoprotein K-like
chr1_+_157403595 9.45 ENSRNOT00000012781
coiled-coil domain containing 90B
chr7_-_36597462 9.38 ENSRNOT00000066322
mitochondrial ribosomal protein L42
chr2_-_198184739 9.37 ENSRNOT00000028751
vacuolar protein sorting 45
chr9_+_16612433 9.37 ENSRNOT00000023979
kelch domain containing 3
chr7_-_97902585 9.31 ENSRNOT00000008382
similar to RIKEN cDNA 9130401M01
chr15_-_41770112 9.24 ENSRNOT00000034400
karyopherin subunit alpha 3
chr7_-_34951644 9.20 ENSRNOT00000030015
vezatin, adherens junctions transmembrane protein
chr9_-_66877972 9.19 ENSRNOT00000023463
WD repeat domain 12
chr1_-_220136470 9.19 ENSRNOT00000026812
actinin alpha 3
chr3_-_91195981 9.16 ENSRNOT00000056935
similar to RIKEN cDNA B230118H07
chr13_+_68785827 8.87 ENSRNOT00000003517
tRNA methyltransferase 1-like
chr4_-_121565212 8.86 ENSRNOT00000088753
coiled-coil-helix-coiled-coil-helix domain containing 6
chr7_-_140342727 8.85 ENSRNOT00000089612
DEAD-box helicase 23
chr7_-_142132173 8.85 ENSRNOT00000026613
cysteine and serine rich nuclear protein 2
chr10_+_38877422 8.80 ENSRNOT00000065229
ENSRNOT00000083162
septin 8
chr3_+_57817693 8.80 ENSRNOT00000067729
ENSRNOT00000047243
ENSRNOT00000013400
dynein cytoplasmic 1 intermediate chain 2
chr1_-_64175099 8.73 ENSRNOT00000091288
NADH:ubiquinone oxidoreductase subunit A3
chr9_-_10801140 8.62 ENSRNOT00000072771
fem-1 homolog A
chr1_+_81372650 8.59 ENSRNOT00000088829
zinc finger protein 428
chr1_-_13395370 8.58 ENSRNOT00000085519
coiled-coil domain containing 28A
chr1_-_71400388 8.56 ENSRNOT00000090327
zinc finger protein 444
chr3_+_177188044 8.51 ENSRNOT00000022073
transcription elongation factor A2
chr3_-_3476215 8.51 ENSRNOT00000024352
UBA domain containing 1
chr2_-_196304169 8.49 ENSRNOT00000028639
sodium channel modifier 1
chr7_-_2786856 8.44 ENSRNOT00000047530
ENSRNOT00000086939
coenzyme Q10A
chr5_+_101526551 8.43 ENSRNOT00000015254
small nuclear RNA activating complex, polypeptide 3
chr20_+_3422461 8.41 ENSRNOT00000084917
ENSRNOT00000079854
tubulin, beta 5 class I
chr10_-_86645529 8.40 ENSRNOT00000011947
mediator complex subunit 24
chr8_+_53365857 8.29 ENSRNOT00000080712
zw10 kinetochore protein
chr2_-_189880743 8.27 ENSRNOT00000018830
SNAP-associated protein
chr5_-_136053210 8.20 ENSRNOT00000025903
kinesin family member 2C
chr3_-_11382004 8.20 ENSRNOT00000047921
ENSRNOT00000064039
dynamin 1
chr7_+_97778260 8.19 ENSRNOT00000064264
TBC1 domain family, member 31
chr12_-_23727535 8.17 ENSRNOT00000085911
ENSRNOT00000001950
deltex E3 ubiquitin ligase 2
chr1_-_86948845 8.17 ENSRNOT00000027212
NFKB inhibitor beta
chr12_-_47438931 8.13 ENSRNOT00000050782
similar to RIKEN cDNA 2210016L21 gene
chr5_-_78267063 8.13 ENSRNOT00000040894
ENSRNOT00000087648
cell division cycle 26
chr1_-_100865894 8.09 ENSRNOT00000027580
prostate tumor overexpressed 1
chr9_+_19880473 8.02 ENSRNOT00000052068
solute carrier family 25, member 27
chr10_+_83476107 8.01 ENSRNOT00000075733
prohibitin
chr10_-_15346236 8.00 ENSRNOT00000088104
ENSRNOT00000027430
calpain 15
chr19_-_38321528 7.94 ENSRNOT00000031977
sphingomyelin phosphodiesterase 3
chr3_-_150885475 7.93 ENSRNOT00000034708
ENSRNOT00000038809
phosphatidylinositol glycan anchor biosynthesis, class U
chr3_-_111013589 7.92 ENSRNOT00000016692
DnaJ heat shock protein family (Hsp40) member C17
chr1_+_203526850 7.89 ENSRNOT00000087065
BUB3 mitotic checkpoint protein
chr10_-_36336628 7.86 ENSRNOT00000030035
zinc finger protein 879
chr6_+_36107147 7.83 ENSRNOT00000006020
retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
chr7_+_2435553 7.83 ENSRNOT00000065593
primase (DNA) subunit 1
chr10_+_15538872 7.82 ENSRNOT00000060078
LUC7-like
chr10_+_46940965 7.78 ENSRNOT00000005366
LLGL1, scribble cell polarity complex component
chr14_+_106393959 7.78 ENSRNOT00000092168
WD repeat containing planar cell polarity effector
chrX_+_71155601 7.77 ENSRNOT00000076453
ENSRNOT00000048521
forkhead box O4
chr4_+_7122890 7.76 ENSRNOT00000076339
ENSRNOT00000076418
ENSRNOT00000014718
ATP binding cassette subfamily F member 2
chr19_+_38039564 7.74 ENSRNOT00000087491
nuclear factor of activated T-cells 3
chrX_-_64908682 7.70 ENSRNOT00000084107
zinc finger C4H2-type containing
chr7_+_25919867 7.68 ENSRNOT00000009625
ENSRNOT00000090153
RIC8 guanine nucleotide exchange factor B
chrX_+_15742978 7.67 ENSRNOT00000015546
coiled-coil domain containing 22
chr13_-_51784639 7.60 ENSRNOT00000089068
protein phosphatase 1, regulatory subunit 12B
chr7_-_40315377 7.52 ENSRNOT00000091319
ENSRNOT00000036141
similar to RIKEN cDNA C430008C19
chr16_-_54137660 7.46 ENSRNOT00000085435
pericentriolar material 1
chr4_+_78024765 7.42 ENSRNOT00000043856
KRAB-A domain containing 1
chr5_+_126976456 7.36 ENSRNOT00000014275
NDC1 transmembrane nucleoporin
chr5_-_135663284 7.35 ENSRNOT00000087237
ENSRNOT00000066869
target of EGR1, member 1 (nuclear)
chr3_+_35014538 7.33 ENSRNOT00000006341
kinesin family member 5C
chr9_+_79944132 7.30 ENSRNOT00000071856
ENSRNOT00000022459
Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
chr1_+_87790104 7.29 ENSRNOT00000074580
zinc finger protein 383-like
chr8_-_28044876 7.29 ENSRNOT00000072152
acyl-CoA dehydrogenase family, member 8
chrX_-_15620841 7.28 ENSRNOT00000085397
PRA1 domain family, member 2
chr8_-_106617597 7.27 ENSRNOT00000070953
mitochondrial ribosomal protein S22
chr16_-_54137485 7.24 ENSRNOT00000014202
pericentriolar material 1
chr5_+_50002184 7.21 ENSRNOT00000010962
akirin 2
chr7_-_29152442 7.16 ENSRNOT00000079774
myosin binding protein C, slow type
chr10_-_106883423 7.14 ENSRNOT00000071406
similar to threonine aldolase 1
chr1_-_185569190 7.11 ENSRNOT00000090773
similar to sid2057p
chr11_+_60907015 7.10 ENSRNOT00000002797
GTP-binding protein 8 (putative)
chr18_+_70996044 7.09 ENSRNOT00000024950
ENSRNOT00000066336
dymeclin
chr10_+_12994683 7.09 ENSRNOT00000004702
host cell factor C1 regulator 1
chr6_-_26546545 7.02 ENSRNOT00000091264
sorting nexin 17
chr12_+_2201891 7.01 ENSRNOT00000091197
ENSRNOT00000001325
resistin
chr4_-_112707270 6.99 ENSRNOT00000009308
mitochondrial ribosomal protein L19
chr2_+_206392200 6.99 ENSRNOT00000026631
round spermatid basic protein 1
chr6_+_111296417 6.97 ENSRNOT00000075425
activator of Hsp90 ATPase activity 1
chr1_+_87248489 6.95 ENSRNOT00000028091
double PHD fingers 1
chr2_+_62150251 6.94 ENSRNOT00000016196
zinc finger RNA binding protein
chr6_-_111176918 6.94 ENSRNOT00000016242
protein-O-mannosyltransferase 2
chr1_-_100530183 6.85 ENSRNOT00000067754
myosin binding protein C, fast-type
chr14_+_81340041 6.80 ENSRNOT00000082612
ENSRNOT00000066391
NOP14 nucleolar protein
chrX_-_84821775 6.78 ENSRNOT00000000174
CHM, Rab escort protein 1
chr19_+_37830917 6.75 ENSRNOT00000025608
nuclear transport factor 2
chr8_+_126411829 6.71 ENSRNOT00000013450
5-azacytidine induced 2
chr1_+_199351628 6.70 ENSRNOT00000078578
branched chain ketoacid dehydrogenase kinase
chr1_+_226947105 6.69 ENSRNOT00000028373
pre-mRNA processing factor 19
chr5_+_2042991 6.66 ENSRNOT00000050236
elongin C
chr1_-_197801634 6.66 ENSRNOT00000090200
nuclear factor of activated T-cells 2 interacting protein
chr18_-_76984203 6.65 ENSRNOT00000089122
CTD phosphatase subunit 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Hcfc1_Six5_Smarcc2_Zfp143

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
10.9 32.8 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
9.3 37.2 GO:0035494 SNARE complex disassembly(GO:0035494)
9.1 27.3 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
8.9 26.8 GO:0090149 mitochondrial membrane fission(GO:0090149)
7.7 23.1 GO:0018343 protein farnesylation(GO:0018343)
7.4 44.3 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
6.1 18.3 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
5.4 21.5 GO:0051105 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
4.9 19.7 GO:0072709 cellular response to sorbitol(GO:0072709)
4.7 18.8 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
4.6 32.4 GO:0032074 negative regulation of nuclease activity(GO:0032074)
4.4 17.5 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
3.7 11.0 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
3.4 17.0 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
3.3 13.4 GO:0098886 modification of dendritic spine(GO:0098886)
3.3 9.9 GO:0071934 thiamine transmembrane transport(GO:0071934)
3.2 9.7 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
3.1 9.2 GO:0031448 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) positive regulation of purine nucleotide catabolic process(GO:0033123)
3.0 15.0 GO:0001579 medium-chain fatty acid transport(GO:0001579)
2.9 17.5 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
2.9 11.5 GO:0044211 CTP salvage(GO:0044211)
2.8 8.4 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
2.7 11.0 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
2.6 18.1 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
2.4 7.3 GO:0090204 protein localization to nuclear pore(GO:0090204)
2.4 12.0 GO:1902774 late endosome to lysosome transport(GO:1902774)
2.4 7.1 GO:0006567 threonine catabolic process(GO:0006567)
2.3 7.0 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
2.3 7.0 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
2.3 6.9 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
2.3 20.5 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
2.2 6.7 GO:0044565 dendritic cell proliferation(GO:0044565)
2.2 24.6 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
2.2 15.1 GO:0071763 nuclear membrane organization(GO:0071763)
2.2 17.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
2.1 8.5 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
2.1 6.3 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
2.1 6.2 GO:0071929 alpha-tubulin acetylation(GO:0071929)
2.0 14.2 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
2.0 8.0 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
2.0 8.0 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
2.0 6.0 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
2.0 23.9 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
2.0 5.9 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
2.0 5.9 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
1.9 5.8 GO:0042350 GDP-L-fucose biosynthetic process(GO:0042350)
1.9 11.4 GO:0042851 L-alanine metabolic process(GO:0042851)
1.9 7.6 GO:0001682 tRNA 5'-leader removal(GO:0001682)
1.9 44.7 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
1.8 7.3 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
1.8 10.6 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
1.7 7.0 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
1.7 12.2 GO:0044036 cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
1.7 18.3 GO:1901642 nucleoside transmembrane transport(GO:1901642)
1.7 19.9 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
1.6 6.6 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
1.6 4.9 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
1.6 6.5 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
1.6 4.8 GO:0042245 RNA repair(GO:0042245)
1.6 6.3 GO:0006014 D-ribose metabolic process(GO:0006014)
1.5 1.5 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
1.5 4.5 GO:0072344 rescue of stalled ribosome(GO:0072344)
1.5 11.8 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
1.5 8.7 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
1.4 2.9 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
1.4 18.4 GO:0051013 microtubule severing(GO:0051013)
1.4 9.9 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
1.4 14.0 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
1.4 2.8 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
1.4 4.1 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
1.4 8.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
1.3 10.8 GO:1990785 response to water-immersion restraint stress(GO:1990785)
1.3 4.0 GO:0010265 SCF complex assembly(GO:0010265)
1.3 21.3 GO:0042407 cristae formation(GO:0042407)
1.3 6.6 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
1.3 15.9 GO:0007096 regulation of exit from mitosis(GO:0007096)
1.3 7.9 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
1.3 1.3 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
1.3 15.6 GO:0006108 malate metabolic process(GO:0006108)
1.3 6.5 GO:0090168 Golgi reassembly(GO:0090168)
1.3 12.8 GO:0000338 protein deneddylation(GO:0000338)
1.3 5.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
1.3 16.3 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
1.2 2.5 GO:1905146 regulation of protein catabolic process in the vacuole(GO:1904350) lysosomal protein catabolic process(GO:1905146)
1.2 14.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
1.2 8.2 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374) synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
1.1 5.5 GO:0048254 snoRNA localization(GO:0048254)
1.1 5.5 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
1.1 4.4 GO:0051958 methotrexate transport(GO:0051958)
1.1 10.9 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
1.1 3.2 GO:2001034 histone H3-K36 dimethylation(GO:0097676) positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
1.1 6.4 GO:0002051 osteoblast fate commitment(GO:0002051)
1.1 6.3 GO:0009838 abscission(GO:0009838)
1.0 4.2 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
1.0 4.2 GO:0034421 post-translational protein acetylation(GO:0034421)
1.0 25.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
1.0 7.8 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
1.0 2.9 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.9 2.8 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.9 1.9 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.9 3.7 GO:0071896 protein localization to adherens junction(GO:0071896)
0.9 6.5 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.9 2.7 GO:0006431 methionyl-tRNA aminoacylation(GO:0006431)
0.9 14.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.9 2.6 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.9 1.7 GO:0061740 late endosomal microautophagy(GO:0061738) protein targeting to lysosome involved in chaperone-mediated autophagy(GO:0061740)
0.9 12.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.9 11.1 GO:0000212 meiotic spindle organization(GO:0000212)
0.8 6.8 GO:0018344 protein geranylgeranylation(GO:0018344)
0.8 2.5 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.8 10.9 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090)
0.8 10.0 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.8 5.0 GO:0006449 regulation of translational termination(GO:0006449)
0.8 4.2 GO:1904117 cellular response to vasopressin(GO:1904117)
0.8 13.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.8 19.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.8 3.2 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.8 6.3 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.8 3.2 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.8 3.1 GO:0032077 positive regulation of deoxyribonuclease activity(GO:0032077)
0.8 6.2 GO:0007000 nucleolus organization(GO:0007000)
0.8 3.1 GO:0043179 rhythmic excitation(GO:0043179)
0.7 1.5 GO:1900195 positive regulation of oocyte maturation(GO:1900195)
0.7 4.4 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.7 8.1 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.7 2.2 GO:1904700 granulosa cell apoptotic process(GO:1904700) regulation of granulosa cell apoptotic process(GO:1904708)
0.7 2.2 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.7 5.8 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.7 3.6 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.7 2.1 GO:0090247 cell motility involved in somitogenic axis elongation(GO:0090247) regulation of cell motility involved in somitogenic axis elongation(GO:0090249)
0.7 2.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.7 2.1 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.7 2.1 GO:0072695 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.7 17.5 GO:0030488 tRNA methylation(GO:0030488)
0.7 2.8 GO:1990928 response to amino acid starvation(GO:1990928)
0.6 7.7 GO:0000733 DNA strand renaturation(GO:0000733)
0.6 1.9 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.6 5.0 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.6 5.0 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.6 4.3 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.6 6.7 GO:0034501 protein localization to kinetochore(GO:0034501)
0.6 1.2 GO:0006999 nuclear pore organization(GO:0006999)
0.6 5.5 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.6 1.2 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.6 9.6 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.6 1.2 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.6 4.2 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.6 4.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.6 1.8 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.6 6.4 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.6 12.7 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.6 1.7 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.6 2.8 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.6 1.1 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.6 1.1 GO:0061511 centriole elongation(GO:0061511)
0.6 4.0 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.6 2.8 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.6 8.9 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.6 4.4 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.5 4.4 GO:0046959 habituation(GO:0046959)
0.5 2.7 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.5 2.2 GO:0048550 negative regulation of pinocytosis(GO:0048550)
0.5 2.7 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.5 1.1 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.5 2.1 GO:0015746 citrate transport(GO:0015746)
0.5 3.7 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.5 10.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.5 1.5 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.5 6.2 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.5 2.6 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.5 11.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.5 6.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.5 10.0 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.5 3.0 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.5 1.5 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.5 4.9 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.5 1.9 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.5 6.7 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.5 4.3 GO:0016246 RNA interference(GO:0016246)
0.5 11.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.5 1.4 GO:0050883 medulla oblongata development(GO:0021550) musculoskeletal movement, spinal reflex action(GO:0050883)
0.5 6.1 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.5 8.8 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.5 3.2 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.5 14.9 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.5 3.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.5 3.2 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.4 4.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.4 15.6 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.4 3.5 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.4 6.5 GO:0048820 hair follicle maturation(GO:0048820)
0.4 3.9 GO:2000344 cortisol metabolic process(GO:0034650) cortisol biosynthetic process(GO:0034651) positive regulation of acrosome reaction(GO:2000344)
0.4 1.3 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.4 5.1 GO:0006415 translational termination(GO:0006415)
0.4 4.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.4 2.5 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.4 9.1 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.4 2.1 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.4 1.2 GO:0018201 peptidyl-glycine modification(GO:0018201)
0.4 4.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.4 3.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.4 3.2 GO:0097327 response to antineoplastic agent(GO:0097327)
0.4 1.2 GO:0098939 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.4 2.0 GO:0031053 primary miRNA processing(GO:0031053)
0.4 3.9 GO:1903350 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.4 5.0 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.4 2.7 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.4 14.6 GO:0032456 endocytic recycling(GO:0032456)
0.4 1.5 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.4 3.4 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.4 10.4 GO:0071305 cellular response to vitamin D(GO:0071305)
0.4 3.0 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.4 4.4 GO:0034063 stress granule assembly(GO:0034063)
0.4 1.5 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.4 18.0 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.4 2.9 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.4 23.1 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.4 2.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.4 1.4 GO:0097681 double-strand break repair via alternative nonhomologous end joining(GO:0097681)
0.3 2.1 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.3 1.4 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.3 6.9 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.3 1.4 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.3 1.4 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3 2.1 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.3 7.1 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.3 22.7 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.3 1.7 GO:0034227 tRNA thio-modification(GO:0034227)
0.3 5.3 GO:0043248 proteasome assembly(GO:0043248)
0.3 7.7 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.3 19.5 GO:0051225 spindle assembly(GO:0051225)
0.3 13.4 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.3 2.2 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.3 2.5 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.3 28.4 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.3 11.1 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.3 0.9 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
0.3 17.4 GO:0008033 tRNA processing(GO:0008033)
0.3 1.2 GO:0070203 regulation of establishment of protein localization to telomere(GO:0070203) positive regulation of establishment of protein localization to telomere(GO:1904851)
0.3 5.0 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.3 0.6 GO:0000019 regulation of mitotic recombination(GO:0000019) negative regulation of telomere capping(GO:1904354)
0.3 2.0 GO:0048733 sebaceous gland development(GO:0048733)
0.3 0.8 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.3 3.6 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.3 3.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.3 0.6 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.3 1.7 GO:0002634 regulation of germinal center formation(GO:0002634)
0.3 1.9 GO:0044598 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.3 2.4 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.3 3.3 GO:0043584 nose development(GO:0043584)
0.3 1.1 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.3 1.6 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.3 1.3 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.3 7.6 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.3 40.4 GO:0000375 RNA splicing, via transesterification reactions(GO:0000375)
0.3 1.0 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.2 2.5 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.2 0.7 GO:0031989 bombesin receptor signaling pathway(GO:0031989)
0.2 1.7 GO:0090344 negative regulation of cell aging(GO:0090344)
0.2 1.0 GO:1904796 regulation of core promoter binding(GO:1904796) positive regulation of core promoter binding(GO:1904798)
0.2 8.8 GO:0002181 cytoplasmic translation(GO:0002181)
0.2 1.2 GO:1904640 response to methionine(GO:1904640)
0.2 0.9 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.2 2.4 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.2 0.9 GO:0090367 negative regulation of mRNA modification(GO:0090367)
0.2 3.2 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.2 9.4 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.2 1.8 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.2 2.5 GO:0006337 nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.2 1.1 GO:0034982 protein processing involved in protein targeting to mitochondrion(GO:0006627) mitochondrial protein processing(GO:0034982)
0.2 5.1 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.2 1.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.2 5.6 GO:0016925 protein sumoylation(GO:0016925)
0.2 0.9 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.2 0.9 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.2 2.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.2 2.5 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.2 7.1 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.2 2.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 1.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.2 0.8 GO:0006554 lysine catabolic process(GO:0006554) L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.2 0.8 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.2 24.9 GO:0006364 rRNA processing(GO:0006364)
0.2 3.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 1.3 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.2 14.4 GO:0016579 protein deubiquitination(GO:0016579)
0.2 3.4 GO:0002347 response to tumor cell(GO:0002347)
0.2 19.6 GO:0019882 antigen processing and presentation(GO:0019882)
0.2 2.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.2 0.5 GO:0010458 exit from mitosis(GO:0010458)
0.2 8.3 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.2 0.5 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.2 1.2 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.2 5.2 GO:0060292 long term synaptic depression(GO:0060292)
0.2 1.7 GO:0019372 lipoxygenase pathway(GO:0019372)
0.2 2.6 GO:0052646 alditol phosphate metabolic process(GO:0052646)
0.2 5.1 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.2 3.9 GO:0010714 positive regulation of collagen metabolic process(GO:0010714)
0.2 1.1 GO:0035934 corticosterone secretion(GO:0035934)
0.2 1.0 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 3.6 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.2 0.5 GO:0070084 protein initiator methionine removal(GO:0070084)
0.2 2.9 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.1 1.5 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 0.9 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 11.8 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.1 0.7 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 10.9 GO:0008380 RNA splicing(GO:0008380)
0.1 1.0 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.5 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.9 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.6 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) positive regulation of sensory perception of pain(GO:1904058)
0.1 1.4 GO:0006527 arginine catabolic process(GO:0006527)
0.1 0.5 GO:0052422 modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.1 10.8 GO:0035308 negative regulation of protein dephosphorylation(GO:0035308)
0.1 6.9 GO:0008088 axo-dendritic transport(GO:0008088)
0.1 1.1 GO:0042048 olfactory behavior(GO:0042048)
0.1 1.0 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 1.9 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.1 1.3 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.1 4.1 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.1 1.1 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 2.8 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.1 1.4 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.1 2.6 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 3.5 GO:0032543 mitochondrial translation(GO:0032543)
0.1 0.6 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 6.5 GO:0051321 meiotic cell cycle(GO:0051321)
0.1 3.8 GO:0031023 microtubule organizing center organization(GO:0031023)
0.1 1.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.9 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.7 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.5 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 0.6 GO:0046477 galactosylceramide metabolic process(GO:0006681) glycosylceramide catabolic process(GO:0046477)
0.1 11.9 GO:0048167 regulation of synaptic plasticity(GO:0048167)
0.1 4.3 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 1.7 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 0.4 GO:0043457 regulation of cellular respiration(GO:0043457)
0.1 1.1 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.1 3.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 5.1 GO:0030500 regulation of bone mineralization(GO:0030500)
0.1 2.9 GO:0001662 behavioral fear response(GO:0001662)
0.1 1.0 GO:0007052 mitotic spindle organization(GO:0007052)
0.1 2.3 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.1 1.0 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 0.5 GO:0000060 protein import into nucleus, translocation(GO:0000060)
0.1 7.0 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.1 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 1.4 GO:0006270 DNA replication initiation(GO:0006270)
0.1 28.6 GO:0015711 organic anion transport(GO:0015711)
0.1 0.7 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012)
0.1 5.8 GO:0019827 stem cell population maintenance(GO:0019827)
0.1 0.5 GO:0002176 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.1 2.2 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.1 0.4 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.1 5.5 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 0.7 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 0.9 GO:0043486 histone exchange(GO:0043486)
0.1 0.6 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.1 2.8 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 1.3 GO:0034508 centromere complex assembly(GO:0034508)
0.1 6.7 GO:0006310 DNA recombination(GO:0006310)
0.1 8.5 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.1 8.1 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.1 1.8 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.1 14.3 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 0.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 6.3 GO:0007059 chromosome segregation(GO:0007059)
0.1 7.8 GO:0060348 bone development(GO:0060348)
0.1 13.9 GO:0051301 cell division(GO:0051301)
0.1 0.2 GO:0048749 compound eye development(GO:0048749)
0.1 1.0 GO:0006754 ATP biosynthetic process(GO:0006754)
0.1 2.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 0.1 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325)
0.1 3.7 GO:0044744 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744)
0.1 4.6 GO:0030316 osteoclast differentiation(GO:0030316)
0.1 0.4 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.2 GO:1901091 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.1 2.0 GO:0006401 RNA catabolic process(GO:0006401)
0.1 1.5 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.1 0.8 GO:0003170 heart valve development(GO:0003170)
0.1 1.7 GO:0032094 response to food(GO:0032094)
0.1 1.7 GO:0006414 translational elongation(GO:0006414)
0.1 0.9 GO:0006284 base-excision repair(GO:0006284)
0.1 0.9 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 0.7 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1 0.4 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 122.0 GO:0006355 regulation of transcription, DNA-templated(GO:0006355)
0.1 2.0 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.1 5.5 GO:0051262 protein tetramerization(GO:0051262)
0.1 0.6 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 3.9 GO:0042113 B cell activation(GO:0042113)
0.1 0.2 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.1 1.3 GO:0008038 neuron recognition(GO:0008038)
0.1 15.2 GO:0006412 translation(GO:0006412)
0.0 0.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 6.9 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0044828 negative regulation by host of viral process(GO:0044793) negative regulation by host of viral genome replication(GO:0044828)
0.0 2.7 GO:0006821 chloride transport(GO:0006821)
0.0 0.0 GO:0071307 cellular response to vitamin K(GO:0071307)
0.0 0.3 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0 1.1 GO:0021549 cerebellum development(GO:0021549)
0.0 0.8 GO:0016573 histone acetylation(GO:0016573) internal peptidyl-lysine acetylation(GO:0018393)
0.0 0.1 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.5 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 2.9 GO:0007626 locomotory behavior(GO:0007626)
0.0 0.1 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 1.7 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.6 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 2.6 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 1.0 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.0 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.2 37.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
5.9 17.8 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
4.8 14.3 GO:0071001 U4/U6 snRNP(GO:0071001)
4.5 17.8 GO:1990745 EARP complex(GO:1990745)
3.6 10.9 GO:1990423 RZZ complex(GO:1990423)
3.1 24.7 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
2.9 23.1 GO:0071439 clathrin complex(GO:0071439)
2.7 8.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
2.6 10.6 GO:0070545 PeBoW complex(GO:0070545)
2.5 10.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
2.4 17.0 GO:0061617 MICOS complex(GO:0061617)
2.3 28.1 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
2.2 17.7 GO:0043203 axon hillock(GO:0043203)
2.1 10.7 GO:0032133 chromosome passenger complex(GO:0032133)
2.1 6.3 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
2.0 6.1 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
2.0 6.0 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
2.0 16.1 GO:0005638 lamin filament(GO:0005638)
2.0 10.0 GO:1990130 Iml1 complex(GO:1990130)
2.0 19.9 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
1.9 19.3 GO:0035748 myelin sheath abaxonal region(GO:0035748)
1.8 5.4 GO:0044611 nuclear pore inner ring(GO:0044611)
1.8 5.3 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
1.7 10.5 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
1.7 8.7 GO:0030689 Noc complex(GO:0030689)
1.7 6.8 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
1.6 14.7 GO:0031209 SCAR complex(GO:0031209)
1.6 8.0 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
1.6 18.9 GO:0005859 muscle myosin complex(GO:0005859)
1.5 9.2 GO:0002142 stereocilia ankle link complex(GO:0002142)
1.5 15.0 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
1.5 8.8 GO:0030677 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
1.5 8.7 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
1.4 11.4 GO:0005869 dynactin complex(GO:0005869)
1.3 6.7 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.3 11.8 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
1.3 18.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
1.3 2.6 GO:0005683 U7 snRNP(GO:0005683)
1.3 6.5 GO:0097361 CIA complex(GO:0097361)
1.3 3.9 GO:0031372 UBC13-MMS2 complex(GO:0031372)
1.2 7.4 GO:0005879 axonemal microtubule(GO:0005879)
1.1 7.8 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
1.1 5.5 GO:0031933 telomeric heterochromatin(GO:0031933)
1.1 10.7 GO:0070652 HAUS complex(GO:0070652)
1.1 40.6 GO:0035861 site of double-strand break(GO:0035861)
1.0 2.1 GO:0035061 interchromatin granule(GO:0035061)
1.0 6.3 GO:0089701 U2AF(GO:0089701)
1.0 5.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
1.0 10.6 GO:0072687 meiotic spindle(GO:0072687)
0.9 23.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.9 13.8 GO:0071004 U2-type prespliceosome(GO:0071004)
0.9 6.3 GO:0071986 Ragulator complex(GO:0071986)
0.9 6.2 GO:0070449 elongin complex(GO:0070449)
0.9 12.4 GO:0035253 ciliary rootlet(GO:0035253)
0.9 8.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.9 1.7 GO:1990836 lysosomal matrix(GO:1990836)
0.9 4.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.8 4.2 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.8 39.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.8 8.4 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.8 2.5 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.8 48.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.8 4.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.8 5.5 GO:0042382 paraspeckles(GO:0042382)
0.8 6.1 GO:0034709 methylosome(GO:0034709)
0.8 6.1 GO:0016272 prefoldin complex(GO:0016272)
0.7 8.9 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.7 2.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.7 13.8 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.7 2.9 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.7 2.8 GO:0031417 NatC complex(GO:0031417)
0.7 2.8 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.7 2.8 GO:0005652 nuclear lamina(GO:0005652)
0.7 5.5 GO:0005687 U4 snRNP(GO:0005687)
0.7 4.2 GO:0070531 BRCA1-A complex(GO:0070531)
0.7 22.1 GO:0034451 centriolar satellite(GO:0034451)
0.7 8.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.6 7.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.6 8.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.6 8.9 GO:0005682 U5 snRNP(GO:0005682)
0.6 28.7 GO:0016592 mediator complex(GO:0016592)
0.6 2.3 GO:0030891 VCB complex(GO:0030891)
0.6 22.7 GO:0060077 inhibitory synapse(GO:0060077)
0.6 6.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.5 5.4 GO:1902555 endoribonuclease complex(GO:1902555)
0.5 2.7 GO:0005685 U1 snRNP(GO:0005685)
0.5 25.9 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.5 9.6 GO:0000800 lateral element(GO:0000800)
0.5 6.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.5 2.1 GO:0030870 Mre11 complex(GO:0030870)
0.5 5.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.5 1.5 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.5 6.9 GO:0071565 nBAF complex(GO:0071565)
0.5 4.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.5 2.0 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.5 6.2 GO:0030914 STAGA complex(GO:0030914)
0.5 12.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.4 49.4 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.4 3.9 GO:0060091 kinocilium(GO:0060091)
0.4 8.7 GO:0043196 varicosity(GO:0043196)
0.4 7.8 GO:0044447 axoneme part(GO:0044447)
0.4 5.2 GO:0005838 proteasome regulatory particle(GO:0005838)
0.4 2.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.4 2.1 GO:0072534 perineuronal net(GO:0072534)
0.4 2.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.4 8.1 GO:0005680 anaphase-promoting complex(GO:0005680)
0.4 10.8 GO:0051233 spindle midzone(GO:0051233)
0.4 11.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.4 2.0 GO:0070761 pre-snoRNP complex(GO:0070761)
0.4 16.2 GO:0048786 presynaptic active zone(GO:0048786)
0.4 5.7 GO:0035102 PRC1 complex(GO:0035102)
0.4 10.0 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.4 2.9 GO:0017119 Golgi transport complex(GO:0017119)
0.4 18.6 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.4 1.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.4 12.8 GO:0008180 COP9 signalosome(GO:0008180)
0.4 5.3 GO:0070938 contractile ring(GO:0070938)
0.3 5.7 GO:0045277 respiratory chain complex IV(GO:0045277)
0.3 22.9 GO:0005811 lipid particle(GO:0005811)
0.3 2.6 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.3 2.8 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.3 4.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.3 1.5 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.3 20.5 GO:0031901 early endosome membrane(GO:0031901)
0.3 0.6 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.3 4.2 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.3 25.5 GO:0031526 brush border membrane(GO:0031526)
0.3 1.5 GO:0097255 R2TP complex(GO:0097255)
0.3 2.3 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.3 4.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.3 1.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.3 12.9 GO:0072686 mitotic spindle(GO:0072686)
0.3 5.5 GO:0036064 ciliary basal body(GO:0036064)
0.3 5.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.3 11.6 GO:0005643 nuclear pore(GO:0005643)
0.3 2.9 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.3 1.3 GO:0061689 tricellular tight junction(GO:0061689)
0.3 5.3 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.2 11.0 GO:0015030 Cajal body(GO:0015030)
0.2 2.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.2 8.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2 16.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 9.4 GO:0000776 kinetochore(GO:0000776)
0.2 55.1 GO:0005874 microtubule(GO:0005874)
0.2 3.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 1.8 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.2 13.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 2.0 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 0.9 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 1.6 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.2 1.3 GO:0031931 TORC1 complex(GO:0031931)
0.2 18.5 GO:0005875 microtubule associated complex(GO:0005875)
0.2 12.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 2.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.2 1.5 GO:0000796 condensin complex(GO:0000796)
0.2 7.9 GO:0031672 A band(GO:0031672)
0.2 2.4 GO:0042581 specific granule(GO:0042581)
0.2 3.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 1.6 GO:0002177 manchette(GO:0002177)
0.2 31.0 GO:0043209 myelin sheath(GO:0043209)
0.2 16.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.2 55.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.2 1.3 GO:0031415 NatA complex(GO:0031415)
0.2 1.8 GO:0072546 ER membrane protein complex(GO:0072546)
0.2 37.6 GO:0030016 myofibril(GO:0030016)
0.2 12.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 21.5 GO:0005681 spliceosomal complex(GO:0005681)
0.2 1.2 GO:0000812 Swr1 complex(GO:0000812)
0.2 5.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 2.0 GO:0005796 Golgi lumen(GO:0005796)
0.2 2.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 4.0 GO:0031461 cullin-RING ubiquitin ligase complex(GO:0031461)
0.1 0.7 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 1.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 9.4 GO:0031966 mitochondrial membrane(GO:0031966)
0.1 1.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 4.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 7.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 24.4 GO:0000790 nuclear chromatin(GO:0000790)
0.1 26.3 GO:0016607 nuclear speck(GO:0016607)
0.1 94.2 GO:0005730 nucleolus(GO:0005730)
0.1 2.9 GO:0005771 multivesicular body(GO:0005771)
0.1 0.7 GO:0000813 ESCRT I complex(GO:0000813)
0.1 3.0 GO:0005921 gap junction(GO:0005921)
0.1 1.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 2.0 GO:0005839 proteasome core complex(GO:0005839)
0.1 7.7 GO:0008021 synaptic vesicle(GO:0008021)
0.1 24.9 GO:0005813 centrosome(GO:0005813)
0.1 17.2 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 0.5 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 18.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 1.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 1.5 GO:0043198 dendritic shaft(GO:0043198)
0.1 2.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.6 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 11.5 GO:0005840 ribosome(GO:0005840)
0.1 0.6 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 2.6 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.7 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.1 5.0 GO:0010008 endosome membrane(GO:0010008)
0.1 1.4 GO:0016363 nuclear matrix(GO:0016363)
0.1 0.8 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 1.6 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 24.1 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 1.4 GO:0042734 presynaptic membrane(GO:0042734)
0.1 7.7 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 2.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.4 GO:0000792 heterochromatin(GO:0000792)
0.0 2.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 8.8 GO:0000139 Golgi membrane(GO:0000139)
0.0 14.7 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 15.1 GO:0005829 cytosol(GO:0005829)
0.0 0.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 13.8 GO:0005739 mitochondrion(GO:0005739)
0.0 1.0 GO:0045095 keratin filament(GO:0045095)
0.0 41.9 GO:0005634 nucleus(GO:0005634)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
12.4 37.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
9.6 9.6 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
8.2 32.8 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
5.7 28.3 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
5.5 27.3 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
4.2 21.1 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700)
4.1 20.5 GO:0031493 nucleosomal histone binding(GO:0031493)
3.9 15.6 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
3.8 23.1 GO:0008318 protein prenyltransferase activity(GO:0008318)
3.8 11.4 GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
3.6 17.8 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
3.5 17.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
3.3 9.9 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
3.0 8.9 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
2.9 11.6 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
2.7 8.0 GO:0031871 proteinase activated receptor binding(GO:0031871)
2.5 25.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
2.5 19.9 GO:0005095 GTPase inhibitor activity(GO:0005095)
2.5 19.8 GO:0030621 U4 snRNA binding(GO:0030621)
2.3 11.5 GO:0004849 uridine kinase activity(GO:0004849)
2.2 21.6 GO:0004526 ribonuclease P activity(GO:0004526)
2.1 8.5 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
2.1 6.3 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
2.1 6.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
2.0 8.2 GO:0000403 Y-form DNA binding(GO:0000403)
2.0 6.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
2.0 5.9 GO:0004832 valine-tRNA ligase activity(GO:0004832)
2.0 7.8 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
1.9 18.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
1.8 29.0 GO:0051400 BH domain binding(GO:0051400)
1.8 5.3 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
1.8 16.0 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
1.8 29.8 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
1.8 10.5 GO:0000150 recombinase activity(GO:0000150)
1.7 6.9 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
1.7 5.0 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
1.6 19.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
1.6 4.9 GO:0030626 U12 snRNA binding(GO:0030626)
1.6 6.4 GO:0016149 translation release factor activity, codon specific(GO:0016149)
1.6 18.8 GO:0050321 tau-protein kinase activity(GO:0050321)
1.5 7.5 GO:0050733 RS domain binding(GO:0050733)
1.5 19.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
1.5 29.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
1.5 11.8 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
1.5 8.7 GO:0003923 GPI-anchor transamidase activity(GO:0003923) GPI anchor binding(GO:0034235)
1.4 8.2 GO:0031749 D2 dopamine receptor binding(GO:0031749)
1.2 5.0 GO:0031544 peptidyl-proline 3-dioxygenase activity(GO:0031544)
1.2 4.8 GO:0035514 DNA demethylase activity(GO:0035514) oxidative RNA demethylase activity(GO:0035515)
1.2 6.0 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
1.2 14.2 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
1.2 12.7 GO:0042577 lipid phosphatase activity(GO:0042577)
1.2 18.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
1.1 8.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
1.1 3.4 GO:0070883 pre-miRNA binding(GO:0070883)
1.1 5.7 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
1.1 32.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
1.1 7.8 GO:0003896 DNA primase activity(GO:0003896)
1.1 6.6 GO:0008420 CTD phosphatase activity(GO:0008420)
1.1 4.4 GO:0015350 methotrexate transporter activity(GO:0015350)
1.1 14.0 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
1.1 3.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
1.1 2.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
1.0 14.1 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
1.0 8.9 GO:0001054 RNA polymerase I activity(GO:0001054)
1.0 4.9 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.9 20.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.9 2.7 GO:0004825 methionine-tRNA ligase activity(GO:0004825)
0.9 6.2 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.9 17.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.9 2.6 GO:0071208 histone pre-mRNA DCP binding(GO:0071208) U7 snRNA binding(GO:0071209)
0.9 18.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.9 17.3 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.9 4.3 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.8 21.1 GO:0031489 myosin V binding(GO:0031489)
0.8 6.7 GO:0031386 protein tag(GO:0031386)
0.8 4.1 GO:0043559 insulin binding(GO:0043559)
0.8 7.3 GO:0036310 annealing helicase activity(GO:0036310)
0.8 3.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.8 4.0 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.8 3.9 GO:0032051 clathrin light chain binding(GO:0032051)
0.8 3.9 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.8 7.6 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.7 3.0 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.7 5.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.7 7.3 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.7 2.9 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.7 20.3 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.7 10.6 GO:0097602 cullin family protein binding(GO:0097602)
0.7 2.8 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.7 6.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.7 2.7 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.7 7.9 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.7 2.0 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.6 1.9 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.6 1.9 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.6 3.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.6 7.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.6 2.5 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.6 4.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.6 21.3 GO:0031369 translation initiation factor binding(GO:0031369)
0.6 4.0 GO:1990226 histone methyltransferase binding(GO:1990226)
0.6 21.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.6 7.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.6 19.0 GO:0050699 WW domain binding(GO:0050699)
0.5 8.7 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.5 2.1 GO:0015137 citrate transmembrane transporter activity(GO:0015137)
0.5 5.8 GO:0051011 microtubule minus-end binding(GO:0051011)
0.5 2.1 GO:0034040 lipid-transporting ATPase activity(GO:0034040) oligopeptide transmembrane transporter activity(GO:0035673)
0.5 4.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.5 26.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.5 4.6 GO:0015266 protein channel activity(GO:0015266)
0.5 2.0 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.5 6.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.5 13.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.5 1.5 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.5 1.5 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.5 7.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.5 9.5 GO:0001671 ATPase activator activity(GO:0001671)
0.5 2.4 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.5 6.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.5 1.4 GO:0016403 dimethylargininase activity(GO:0016403)
0.5 14.0 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.5 1.9 GO:0061665 SUMO ligase activity(GO:0061665)
0.5 12.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.5 15.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.5 6.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.4 8.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.4 10.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.4 1.7 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.4 8.4 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.4 8.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.4 4.9 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.4 5.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.4 1.2 GO:0019961 interferon binding(GO:0019961)
0.4 3.2 GO:0070034 telomerase RNA binding(GO:0070034)
0.4 43.7 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.4 3.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.4 2.6 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.4 1.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 3.8 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.3 2.0 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3 1.7 GO:0043515 kinetochore binding(GO:0043515)
0.3 7.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.3 7.0 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.3 1.3 GO:0050682 AF-2 domain binding(GO:0050682)
0.3 5.2 GO:0051861 glycolipid binding(GO:0051861)
0.3 2.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.3 8.5 GO:0017091 AU-rich element binding(GO:0017091)
0.3 1.8 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.3 2.1 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.3 24.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.3 2.3 GO:0030955 potassium ion binding(GO:0030955)
0.3 3.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.3 1.4 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.3 3.1 GO:0031402 sodium ion binding(GO:0031402)
0.3 18.2 GO:0032947 protein complex scaffold(GO:0032947)
0.3 0.6 GO:0097677 STAT family protein binding(GO:0097677)
0.3 7.5 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.3 3.9 GO:0017136 NAD-dependent histone deacetylase activity(GO:0017136)
0.3 1.8 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.3 9.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.3 1.5 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.2 10.9 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.2 0.7 GO:0004946 bombesin receptor activity(GO:0004946)
0.2 1.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.2 5.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 1.0 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.2 2.9 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 7.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 1.9 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.2 3.9 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 3.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 2.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 0.4 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.2 10.4 GO:0017022 myosin binding(GO:0017022)
0.2 4.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.2 55.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 2.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 6.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 0.4 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.2 0.8 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.2 0.6 GO:0003691 double-stranded telomeric DNA binding(GO:0003691) G-quadruplex DNA binding(GO:0051880)
0.2 6.2 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.2 1.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.2 1.0 GO:0001729 ceramide kinase activity(GO:0001729)
0.2 5.7 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 10.4 GO:0002039 p53 binding(GO:0002039)
0.2 0.4 GO:0000339 RNA cap binding(GO:0000339)
0.2 1.3 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.2 5.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 27.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.2 24.2 GO:0000149 SNARE binding(GO:0000149)
0.2 4.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.2 1.0 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.2 1.0 GO:0045504 dynein heavy chain binding(GO:0045504)
0.2 2.7 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.2 1.9 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.2 2.1 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.2 2.0 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.2 7.4 GO:0035064 methylated histone binding(GO:0035064)
0.1 15.3 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 1.2 GO:0008172 S-methyltransferase activity(GO:0008172) cobalamin binding(GO:0031419)
0.1 0.9 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) chondroitin sulfotransferase activity(GO:0034481)
0.1 4.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.9 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.1 1.7 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 16.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.7 GO:0030620 U2 snRNA binding(GO:0030620)
0.1 1.8 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 2.1 GO:0004532 exoribonuclease activity(GO:0004532)
0.1 2.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 23.0 GO:0061659 ubiquitin-like protein ligase activity(GO:0061659)
0.1 0.8 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 24.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 2.9 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 0.5 GO:0043404 corticotrophin-releasing factor receptor activity(GO:0015056) corticotropin-releasing hormone receptor activity(GO:0043404)
0.1 0.9 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 1.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 1.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 1.6 GO:0001190 RNA polymerase II transcription coactivator activity(GO:0001105) transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 12.1 GO:0042393 histone binding(GO:0042393)
0.1 2.2 GO:0071949 FAD binding(GO:0071949)
0.1 2.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 1.0 GO:0042285 xylosyltransferase activity(GO:0042285)
0.1 0.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 3.7 GO:0030295 protein kinase activator activity(GO:0030295)
0.1 21.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 76.7 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1 0.5 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 1.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 1.2 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.6 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 11.8 GO:0001047 core promoter binding(GO:0001047)
0.1 10.6 GO:0044325 ion channel binding(GO:0044325)
0.1 0.7 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 1.5 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)
0.1 1.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 1.6 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 1.8 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 160.4 GO:0003676 nucleic acid binding(GO:0003676)
0.1 2.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.9 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 1.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.3 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.2 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.1 1.2 GO:0051393 alpha-actinin binding(GO:0051393)
0.1 1.3 GO:0034212 peptide N-acetyltransferase activity(GO:0034212)
0.1 1.6 GO:0051213 dioxygenase activity(GO:0051213)
0.1 0.4 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 2.9 GO:0003682 chromatin binding(GO:0003682)
0.0 3.1 GO:0005518 collagen binding(GO:0005518)
0.0 1.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 1.5 GO:0043621 protein self-association(GO:0043621)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 1.3 GO:0019894 kinesin binding(GO:0019894)
0.0 1.1 GO:0004518 nuclease activity(GO:0004518)
0.0 1.5 GO:0051087 chaperone binding(GO:0051087)
0.0 1.5 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.7 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 1.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 2.6 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 2.1 GO:0005267 potassium channel activity(GO:0005267)
0.0 0.4 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.2 GO:0005521 lamin binding(GO:0005521)
0.0 1.4 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 1.1 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 3.3 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 1.3 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.0 0.6 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 2.2 GO:0008083 growth factor activity(GO:0008083)
0.0 0.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 1.6 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.0 0.2 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 5.9 GO:0008270 zinc ion binding(GO:0008270)
0.0 0.1 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0001155 RNA polymerase III transcription factor binding(GO:0001025) TFIIIA-class transcription factor binding(GO:0001155)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 32.7 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
1.4 15.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
1.2 21.8 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
1.0 44.5 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.9 34.4 PID AURORA A PATHWAY Aurora A signaling
0.8 13.9 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.7 35.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.7 22.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.7 24.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.6 22.5 PID AURORA B PATHWAY Aurora B signaling
0.6 26.1 PID ATR PATHWAY ATR signaling pathway
0.6 6.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.5 32.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.4 11.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.4 11.2 PID PLK1 PATHWAY PLK1 signaling events
0.4 17.9 PID E2F PATHWAY E2F transcription factor network
0.3 10.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.3 6.1 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.3 9.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.3 4.1 PID BARD1 PATHWAY BARD1 signaling events
0.2 6.9 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.2 17.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 14.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.2 5.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.2 10.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.2 8.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 5.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 2.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 2.1 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.2 8.7 PID P73PATHWAY p73 transcription factor network
0.2 2.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 2.8 PID ATM PATHWAY ATM pathway
0.1 1.9 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 0.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 0.3 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 3.5 PID CONE PATHWAY Visual signal transduction: Cones
0.1 6.3 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 4.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 3.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 1.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 0.9 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 1.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 5.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 1.2 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 2.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 9.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 1.7 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.6 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.7 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.3 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 53.7 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
2.5 46.8 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
2.3 24.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
2.0 31.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
1.9 66.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
1.5 23.9 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
1.4 26.7 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
1.4 4.2 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
1.3 6.6 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
1.3 2.6 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
1.1 19.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
1.0 66.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.9 19.7 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.9 8.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.9 8.2 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.9 5.4 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.8 14.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.7 2.2 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.7 12.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.7 18.4 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.7 1.3 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.6 14.2 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.6 51.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.6 11.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.6 1.8 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.6 3.9 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.5 7.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.5 6.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.5 10.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.5 14.8 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.5 61.6 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.4 21.3 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.4 15.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.4 10.3 REACTOME KINESINS Genes involved in Kinesins
0.4 7.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.4 1.2 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.4 6.4 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.4 25.7 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.4 5.1 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.4 4.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.3 3.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.3 8.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.3 8.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.3 8.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.3 6.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.3 10.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.3 6.6 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.3 1.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.3 4.0 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.3 10.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.3 6.8 REACTOME TRANSLATION Genes involved in Translation
0.3 16.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.2 1.9 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.2 3.0 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.2 2.8 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 3.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2 3.2 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.2 2.5 REACTOME ORC1 REMOVAL FROM CHROMATIN Genes involved in Orc1 removal from chromatin
0.2 2.7 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.2 1.5 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.2 18.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 8.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.2 8.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.2 3.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.2 2.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 2.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.2 4.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 6.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.2 2.0 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.2 4.4 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 2.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 14.1 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.1 1.9 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.1 1.9 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 9.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 2.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 2.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 2.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 5.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 2.2 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.1 1.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 3.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 0.8 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.1 2.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 0.9 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 0.6 REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.1 1.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 1.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 2.6 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 5.2 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 2.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 0.6 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
0.1 1.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 2.0 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 1.1 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 1.1 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 0.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.6 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 6.3 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.1 4.9 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.1 7.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 1.3 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 4.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.4 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP