ISMARA results: Gtf2i

Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation

Downloads

Results for Gtf2i_Gtf2f1

Z-value: 1.59

Motif logo

Transcription factors associated with Gtf2i_Gtf2f1

Gene Symbol	Gene ID	Gene Info
Gtf2i NCBI RGD Ensembl	ENSRNOG00000001479	general transcription factor II I
Gtf2f1 NCBI RGD Ensembl	ENSRNOG00000047134	general transcription factor IIF subunit 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Gtf2f1	rn6_v1_chr9_+_10033011_10033011	0.71	9.2e-50	Click!
Gtf2i	rn6_v1_chr12_+_25435567_25435567	0.70	1.6e-47	Click!

Activity profile of Gtf2i_Gtf2f1 motif

Sorted Z-values of Gtf2i_Gtf2f1 motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr10_+_56627411 Show fit	52.44	ENSRNOT00000089108 ENSRNOT00000068493	Dlg4 NCBI RGD Ensembl Show fit	discs large MAGUK scaffold protein 4
chrX_-_124464963 Show fit	52.18	ENSRNOT00000036472 ENSRNOT00000077697	Tmem255a NCBI RGD Ensembl Show fit	transmembrane protein 255A
chrX_-_123662350 Show fit	38.86	ENSRNOT00000092624	Sept6 NCBI RGD Ensembl Show fit	septin 6
chr17_-_10766253 Show fit	38.13	ENSRNOT00000000117	Cplx2 NCBI RGD Ensembl Show fit	complexin 2
chr20_+_5535432 Show fit	37.06	ENSRNOT00000040859	Syngap1 NCBI RGD Ensembl Show fit	synaptic Ras GTPase activating protein 1
chr5_-_75319765 Show fit	35.99	ENSRNOT00000085698	Svep1 NCBI RGD Ensembl Show fit	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr19_+_2393059 Show fit	35.81	ENSRNOT00000018535	Cdh11 NCBI RGD Ensembl Show fit	cadherin 11
chr14_+_70780623 Show fit	33.48	ENSRNOT00000083871 ENSRNOT00000058803	Ldb2 NCBI RGD Ensembl Show fit	LIM domain binding 2
chr11_-_11585765 Show fit	30.26	ENSRNOT00000066439	Robo2 NCBI RGD Ensembl Show fit	roundabout guidance receptor 2
chr5_-_75319189 Show fit	29.72	ENSRNOT00000047200	Svep1 NCBI RGD Ensembl Show fit	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Gtf2i_Gtf2f1

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	102.3	GO:0008542	visual learning(GO:0008542)
3.8	60.1	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
1.5	57.3	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
10.5	52.4	GO:0098970	receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
4.9	48.9	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
8.0	48.2	GO:0014053	negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.1	45.3	GO:0043547	positive regulation of GTPase activity(GO:0043547)
14.9	44.8	GO:1902748	positive regulation of lens fiber cell differentiation(GO:1902748)
6.3	44.3	GO:0099525	presynaptic dense core granule exocytosis(GO:0099525)
13.2	39.6	GO:1990926	short-term synaptic potentiation(GO:1990926)

Showing 1 to 10 of 721 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	107.1	GO:0043198	dendritic shaft(GO:0043198)
0.7	96.6	GO:0030426	growth cone(GO:0030426)
7.2	86.2	GO:0098839	postsynaptic density membrane(GO:0098839)
0.6	84.3	GO:0043204	perikaryon(GO:0043204)
11.9	71.3	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.4	67.2	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.6	66.9	GO:0016363	nuclear matrix(GO:0016363)
22.2	66.5	GO:0032173	septin collar(GO:0032173)
0.3	60.8	GO:0031252	cell leading edge(GO:0031252)
0.4	59.9	GO:0060076	excitatory synapse(GO:0060076)

Showing 1 to 10 of 297 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
4.3	129.1	GO:0017075	syntaxin-1 binding(GO:0017075)
0.3	127.9	GO:0005525	GTP binding(GO:0005525)
1.3	101.9	GO:0005518	collagen binding(GO:0005518)
0.6	77.0	GO:0017124	SH3 domain binding(GO:0017124)
10.2	61.4	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
7.6	52.9	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
1.1	52.8	GO:0048365	Rac GTPase binding(GO:0048365)
0.2	48.5	GO:0015631	tubulin binding(GO:0015631)
11.8	47.0	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
3.1	43.4	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)

Showing 1 to 10 of 413 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	118.4	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.5	80.4	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
2.0	65.3	ST GA12 PATHWAY	G alpha 12 Pathway
1.6	62.7	PID REELIN PATHWAY	Reelin signaling pathway
0.9	48.6	PID RHOA REG PATHWAY	Regulation of RhoA activity
1.5	46.3	PID RAS PATHWAY	Regulation of Ras family activation
0.9	45.3	NABA COLLAGENS	Genes encoding collagen proteins
1.0	41.7	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
1.0	41.5	PID NCADHERIN PATHWAY	N-cadherin signaling events
1.3	39.9	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte

Showing 1 to 10 of 98 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	90.5	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.7	73.5	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
1.0	60.7	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
4.2	58.5	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
2.5	54.7	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
1.9	54.6	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.8	48.7	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
1.8	45.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.3	44.2	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.5	42.5	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation

Showing 1 to 10 of 143 entries

Results for Gtf2i_Gtf2f1

Z-value: 1.59

Motif logo

Transcription factors associated with Gtf2i_Gtf2f1

Activity-expression correlation:

Activity profile of Gtf2i_Gtf2f1 motif

Sorted Z-values of Gtf2i_Gtf2f1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Gtf2i_Gtf2f1

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: