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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Gsx2_Hoxd3_Vax1

Z-value: 0.62

Motif logo

Transcription factors associated with Gsx2_Hoxd3_Vax1

Gene Symbol Gene ID Gene Info
ENSRNOG00000002266 GS homeobox 2
ENSRNOG00000001577 homeo box D3
ENSRNOG00000008824 ventral anterior homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxd3rn6_v1_chr3_+_61658245_616582450.327.6e-09Click!
Vax1rn6_v1_chr1_-_280338813_2803388130.071.9e-01Click!
Gsx2rn6_v1_chr14_-_35652709_35652709-0.027.8e-01Click!

Activity profile of Gsx2_Hoxd3_Vax1 motif

Sorted Z-values of Gsx2_Hoxd3_Vax1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_76488216 29.77 ENSRNOT00000080024
neurocalcin delta
chr8_+_33239139 27.89 ENSRNOT00000011589
Rho GTPase activating protein 32
chr2_-_158133861 26.36 ENSRNOT00000090700
ventricular zone expressed PH domain-containing 1
chr1_+_87224677 24.02 ENSRNOT00000028070
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr17_-_87826421 18.94 ENSRNOT00000068156
Rho GTPase activating protein 21
chr5_-_161981441 18.02 ENSRNOT00000020316
podoplanin
chr8_-_7426611 12.02 ENSRNOT00000031492
Rho GTPase activating protein 42
chr2_-_138833933 11.80 ENSRNOT00000013343
protocadherin 18
chr2_-_57935334 11.52 ENSRNOT00000022319
ENSRNOT00000085599
ENSRNOT00000077790
ENSRNOT00000035821
solute carrier family 1 member 3
chr9_+_73418607 11.13 ENSRNOT00000092547
microtubule-associated protein 2
chr12_-_19167015 11.13 ENSRNOT00000001797
gap junction protein, gamma 3
chr18_+_30036887 9.96 ENSRNOT00000077824
protocadherin alpha 4
chr7_-_101138860 9.52 ENSRNOT00000077137

chr17_+_11683862 8.75 ENSRNOT00000024766
msh homeobox 2
chr5_-_168734296 8.60 ENSRNOT00000066120
calmodulin binding transcription activator 1
chr1_+_59156251 8.59 ENSRNOT00000017442
limb and CNS expressed 1
chr2_-_158156444 8.37 ENSRNOT00000088559
ventricular zone expressed PH domain-containing 1
chr2_+_266315036 7.89 ENSRNOT00000055245
wntless Wnt ligand secretion mediator
chr7_-_101138373 7.83 ENSRNOT00000043257
Ab1-152
chr6_+_2216623 7.63 ENSRNOT00000008045
regulator of microtubule dynamics 2
chrX_+_6273733 7.61 ENSRNOT00000074275
NDP, norrin cystine knot growth factor
chr18_+_32336102 7.43 ENSRNOT00000018577
fibroblast growth factor 1
chr5_-_17061837 7.34 ENSRNOT00000011892
proenkephalin
chr2_-_40386669 7.02 ENSRNOT00000014074
ELOVL fatty acid elongase 7
chr11_-_62067655 6.93 ENSRNOT00000093382
zinc finger and BTB domain containing 20
chr1_+_217345545 6.73 ENSRNOT00000071741
SH3 and multiple ankyrin repeat domains 2
chrX_+_14019961 6.50 ENSRNOT00000004785
synaptotagmin-like 5
chr6_+_104291071 6.48 ENSRNOT00000006798
solute carrier family 39, member 9
chr6_+_8284878 6.37 ENSRNOT00000009581
solute carrier family 3 member 1
chr2_+_252090669 6.34 ENSRNOT00000020656
lysophosphatidic acid receptor 3
chr18_-_26656879 6.20 ENSRNOT00000086729
erythrocyte membrane protein band 4.1 like 4A
chr3_-_154627257 6.12 ENSRNOT00000018328
transglutaminase 2
chr2_-_238369692 5.93 ENSRNOT00000041583
Rho guanine nucleotide exchange factor 38
chr7_-_143497108 5.91 ENSRNOT00000048613
keratin 76
chrX_+_84064427 5.87 ENSRNOT00000046364
zinc finger protein 711
chr9_-_44419998 5.67 ENSRNOT00000091397
ENSRNOT00000083747
testis specific 10
chr11_+_36851038 5.65 ENSRNOT00000002221
ENSRNOT00000061047
Purkinje cell protein 4
chr2_+_145174876 5.63 ENSRNOT00000040631
mab-21 like 1
chr5_-_17061361 5.58 ENSRNOT00000089318
proenkephalin
chr17_-_84247038 5.52 ENSRNOT00000068553
nebulette
chr2_+_158097843 5.49 ENSRNOT00000016541
pentraxin 3
chr2_+_54466280 5.31 ENSRNOT00000033112
complement C6
chr2_+_66940057 5.31 ENSRNOT00000043050
cadherin 9
chr5_+_64476317 5.27 ENSRNOT00000017217
collagen alpha-1(XV) chain-like
chr9_-_44237117 5.23 ENSRNOT00000068496
similar to putative protein (5S487)
chr2_-_219262901 5.16 ENSRNOT00000037068
G-protein coupled receptor 88
chr18_+_51523758 5.06 ENSRNOT00000078518
GRAM domain containing 3
chr8_-_78233430 5.01 ENSRNOT00000083220
cingulin-like 1
chrX_+_65566047 4.95 ENSRNOT00000092103
hephaestin
chr17_-_14627937 4.89 ENSRNOT00000020532
osteoglycin
chr2_-_60657712 4.87 ENSRNOT00000040348
retinoic acid induced 14
chr6_-_144123596 4.65 ENSRNOT00000006144
ENSRNOT00000087845
WD repeat domain 60
chr6_+_104291340 4.64 ENSRNOT00000089313
solute carrier family 39, member 9
chr16_-_10802512 4.64 ENSRNOT00000079554
bone morphogenetic protein receptor type 1A
chr18_-_24735349 4.55 ENSRNOT00000036537
G protein-coupled receptor 17
chr3_+_15560712 4.54 ENSRNOT00000010218
prostaglandin-endoperoxide synthase 1
chr20_+_13817795 4.50 ENSRNOT00000036518
glutathione S-transferase, theta 3
chr1_-_256734719 4.47 ENSRNOT00000021546
ENSRNOT00000089456
myoferlin
chr8_+_44136496 4.35 ENSRNOT00000087022
sodium voltage-gated channel beta subunit 3
chr4_+_139670092 4.31 ENSRNOT00000008879
leucine rich repeat neuronal 1
chr4_-_84740909 4.27 ENSRNOT00000013088
secernin 1
chr4_-_72143748 4.20 ENSRNOT00000024428
TRPM8 channel-associated factor 1
chr10_+_54156649 3.96 ENSRNOT00000074718
growth arrest specific 7
chr1_-_236900904 3.95 ENSRNOT00000066846

chr2_+_202200797 3.91 ENSRNOT00000042263
ENSRNOT00000071938
sperm associated antigen 17
chr4_+_158088505 3.88 ENSRNOT00000026643
von Willebrand factor
chr20_-_30947484 3.81 ENSRNOT00000065614
phosphatase domain containing, paladin 1
chr10_-_51778939 3.80 ENSRNOT00000078675
ENSRNOT00000057562
myocardin
chr12_-_6078411 3.80 ENSRNOT00000001197
relaxin/insulin-like family peptide receptor 2
chr4_-_100252755 3.70 ENSRNOT00000017301
vesicle-associated membrane protein 8
chr5_-_147412705 3.53 ENSRNOT00000010688
similar to mKIAA1522 protein
chr18_+_30435119 3.53 ENSRNOT00000027190
protocadherin beta 8
chr5_+_18901039 3.53 ENSRNOT00000012066
family with sequence similarity 110, member B
chr14_-_82975263 3.49 ENSRNOT00000024165
solute carrier family 5 member 1
chrX_-_69218526 3.43 ENSRNOT00000092321
ENSRNOT00000074071
ENSRNOT00000092571
praja ring finger ubiquitin ligase 1
chr1_-_224698514 3.42 ENSRNOT00000024234
solute carrier family 22, member 25
chr4_-_62860446 3.41 ENSRNOT00000015752
family with sequence similarity 180, member A
chr16_-_3765917 3.38 ENSRNOT00000088284
double homeobox B-like 1
chr3_-_46942966 3.28 ENSRNOT00000087439
RNA binding motif, single stranded interacting protein 1
chr2_+_143656793 3.09 ENSRNOT00000084527
ENSRNOT00000017453
periostin
chr1_-_67065797 3.03 ENSRNOT00000048152
vomeronasal 1 receptor 46
chr10_-_82117109 3.02 ENSRNOT00000079711
ATP binding cassette subfamily C member 3
chr3_+_5709236 3.00 ENSRNOT00000061201
ENSRNOT00000070887
dopamine beta-hydroxylase
chr9_-_85243001 2.97 ENSRNOT00000020219
secretogranin II
chr14_-_45859908 2.96 ENSRNOT00000086994
phosphoglucomutase 2
chr3_+_148654668 2.95 ENSRNOT00000081370
transmembrane 9 superfamily member 4
chr14_+_39964588 2.91 ENSRNOT00000003240
gamma-aminobutyric acid type A receptor gamma 1 subunit
chr7_+_26256459 2.88 ENSRNOT00000010986
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2
chr1_-_215033460 2.81 ENSRNOT00000044565
dual specificity phosphatase 8
chr9_+_67234303 2.79 ENSRNOT00000050179
abl-interactor 2
chr2_-_187113717 2.75 ENSRNOT00000020147
leucine rich repeat containing 71
chr2_+_248398917 2.71 ENSRNOT00000045855
guanylate binding protein 1
chr11_+_70056624 2.71 ENSRNOT00000002447

chr8_-_102149912 2.66 ENSRNOT00000011263
similar to Ab2-095
chr8_-_33121002 2.63 ENSRNOT00000047211
LRRGT00010-like
chr1_+_48077033 2.62 ENSRNOT00000020100
MAS1 proto-oncogene, G protein-coupled receptor
chr1_+_168575090 2.57 ENSRNOT00000048299
olfactory receptor 103
chr11_-_61234944 2.52 ENSRNOT00000059680
cilia and flagella associated protein 44
chr1_-_101095594 2.49 ENSRNOT00000027944
Fc fragment of IgG receptor and transporter
chr1_+_99505677 2.41 ENSRNOT00000024645
zinc finger protein 719
chr6_+_95205153 2.41 ENSRNOT00000007339
leucine rich repeat containing 9
chr1_-_23556241 2.40 ENSRNOT00000072943
syntaxin-7-like
chr12_+_2140203 2.37 ENSRNOT00000084906
calmodulin regulated spectrin-associated protein family, member 3
chr2_-_33025271 2.34 ENSRNOT00000074941
microtubule associated serine/threonine kinase family member 4
chr8_-_84835060 2.32 ENSRNOT00000007867
leucine rich repeat containing 1
chr5_-_133959447 2.32 ENSRNOT00000011985
cytochrome P450, family 4, subfamily x, polypeptide 1
chr7_-_107203897 2.30 ENSRNOT00000086263
leucine rich repeat containing 6
chr3_+_159368273 2.30 ENSRNOT00000041688
serum/glucocorticoid regulated kinase 2
chr3_-_52664209 2.26 ENSRNOT00000065126
ENSRNOT00000079020
sodium voltage-gated channel alpha subunit 9
chr10_+_103395511 2.21 ENSRNOT00000004256
G protein-coupled receptor, class C, group 5, member C
chr15_+_11298478 2.18 ENSRNOT00000007672
leucine rich repeat containing 3B
chr6_-_3355339 2.14 ENSRNOT00000084602
mitogen-activated protein kinase kinase kinase kinase 3
chr1_+_80279706 2.13 ENSRNOT00000047105
protein phosphatase 1, regulatory subunit 13 like
chr4_-_176909075 2.12 ENSRNOT00000067489
ATP binding cassette subfamily C member 9
chr8_-_17525906 2.09 ENSRNOT00000007855
N-acetylated alpha-linked acidic dipeptidase 2
chr7_+_6644643 2.07 ENSRNOT00000051670
olfactory receptor 962
chr4_+_87608301 1.98 ENSRNOT00000058702
vomeronasal 1 receptor 71
chr13_+_60619309 1.97 ENSRNOT00000082129

chr13_+_82355886 1.97 ENSRNOT00000076757
selectin E
chr2_-_96509424 1.95 ENSRNOT00000090866
zinc finger, C2HC-type containing 1A
chr1_-_72184265 1.90 ENSRNOT00000047856
vomeronasal 1 receptor 36
chr14_-_77810147 1.88 ENSRNOT00000035427
cytokine like 1
chr10_+_104582955 1.87 ENSRNOT00000009733
unkempt family zinc finger
chr15_+_108526014 1.87 ENSRNOT00000017211
transmembrane 9 superfamily member 2
chr13_+_82355471 1.85 ENSRNOT00000030677
selectin E
chr2_-_181900856 1.84 ENSRNOT00000082156
lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)
chr18_+_17043903 1.84 ENSRNOT00000068139
formin homology 2 domain containing 3
chr7_+_72924799 1.83 ENSRNOT00000008969
lysosomal protein transmembrane 4 beta
chr14_+_34446616 1.82 ENSRNOT00000002976
clock circadian regulator
chr4_-_55011415 1.67 ENSRNOT00000056996
glutamate metabotropic receptor 8
chr3_-_14643897 1.63 ENSRNOT00000082008
ENSRNOT00000025983
glycoprotein, alpha-galactosyltransferase 1
chr1_-_275882444 1.63 ENSRNOT00000083215
glycerol-3-phosphate acyltransferase, mitochondrial
chr20_+_3230052 1.57 ENSRNOT00000078454
RT1 class I, locus T24, gene 3
chr2_-_25235275 1.56 ENSRNOT00000061580
F2R like trypsin receptor 1
chr12_+_17253791 1.54 ENSRNOT00000083814
zinc finger AN1-type containing 2A
chr12_-_52658275 1.54 ENSRNOT00000041981
zinc finger protein 605
chr6_+_29977797 1.51 ENSRNOT00000071784
FK506 binding protein 1B
chr15_+_45712821 1.49 ENSRNOT00000083381
ENSRNOT00000045833
family with sequence similarity 124 member A
chr8_+_59344083 1.46 ENSRNOT00000031175
cellular retinoic acid binding protein 1
chr7_+_71157664 1.41 ENSRNOT00000005919
short chain dehydrogenase/reductase family 9C, member 7
chr14_-_5101177 1.38 ENSRNOT00000002888
leucine rich repeat containing 8 family, member D
chr3_-_3594475 1.35 ENSRNOT00000064861
RGD1564379
chr7_-_14364178 1.34 ENSRNOT00000090673
A-kinase anchoring protein 8 like
chr2_-_93985378 1.33 ENSRNOT00000075493
fatty acid binding protein 5, epidermal
chr20_+_3246739 1.33 ENSRNOT00000061299
RT1 class I, locus T24, gene 2
chr3_-_111087347 1.33 ENSRNOT00000018277
ras homolog family member V
chrX_-_152642531 1.29 ENSRNOT00000085037
gamma-aminobutyric acid type A receptor alpha3 subunit
chr10_+_86399827 1.29 ENSRNOT00000009299
growth factor receptor bound protein 7
chr9_+_84203072 1.20 ENSRNOT00000018882
sphingosine-1-phosphate phosphatase 2
chr3_+_117421604 1.18 ENSRNOT00000008860
ENSRNOT00000008857
solute carrier family 12 member 1
chr10_+_64174931 1.17 ENSRNOT00000035948
RGD1565611
chr5_+_129756149 1.13 ENSRNOT00000067277
DMRT-like family A2
chr1_+_86429262 1.12 ENSRNOT00000045789
vomeronasal 1 receptor 3
chr2_+_243577082 1.12 ENSRNOT00000016556
alcohol dehydrogenase 6A (class V)
chr12_+_19328957 1.10 ENSRNOT00000033288
canopy FGF signaling regulator 4
chr1_+_75298364 1.05 ENSRNOT00000018981
vomeronasal 1 receptor 61
chr1_+_170205591 1.05 ENSRNOT00000071063
similar to olfactory receptor 692
chr4_-_88684415 1.03 ENSRNOT00000009001
similar to 40S ribosomal protein S7 (S8)
chr8_+_41302631 1.02 ENSRNOT00000076963
olfactory receptor 143-like
chr3_-_160561741 1.00 ENSRNOT00000018364
potassium voltage-gated channel, modifier subfamily S, member 1
chr3_-_76102782 0.98 ENSRNOT00000007690
olfactory receptor 602
chr10_-_47546037 0.96 ENSRNOT00000066109
aldehyde dehydrogenase 3 family, member A2
chr1_+_277355619 0.96 ENSRNOT00000022788
NHL repeat containing 2
chr15_-_54528480 0.93 ENSRNOT00000066888
fibronectin type III domain containing 3a
chrX_+_68627313 0.89 ENSRNOT00000076699
ENSRNOT00000076795
ENSRNOT00000008705
Yip1 domain family, member 6
chr6_-_104290579 0.88 ENSRNOT00000066014
enhancer of rudimentary homolog (Drosophila)
chr5_+_58995249 0.88 ENSRNOT00000023411
coiled-coil domain containing 107
chr14_-_82658891 0.87 ENSRNOT00000006841
UV-stimulated scaffold protein A
chr4_+_6827429 0.87 ENSRNOT00000071737
Ras homolog enriched in brain
chr13_-_89545182 0.86 ENSRNOT00000078402
Purkinje cell protein 4-like 1
chrM_+_9870 0.83 ENSRNOT00000044582
mitochondrially encoded NADH 4L dehydrogenase
chr17_-_54678710 0.83 ENSRNOT00000046013
zinc finger E-box binding homeobox 1
chr1_-_190370499 0.80 ENSRNOT00000084389

chr6_-_127319362 0.80 ENSRNOT00000012256
DEAD-box helicase 24
chr7_-_55604403 0.79 ENSRNOT00000088732
ataxin 7-like 3B
chr17_+_45801528 0.78 ENSRNOT00000089221
olfactory receptor 1664
chr15_-_93765498 0.76 ENSRNOT00000093297
MYC binding protein 2, E3 ubiquitin protein ligase
chr10_-_47546345 0.72 ENSRNOT00000077461
aldehyde dehydrogenase 3 family, member A2
chr10_-_52290657 0.71 ENSRNOT00000005293
mitogen activated protein kinase kinase 4
chr7_-_3229167 0.69 ENSRNOT00000008929
transmembrane protein 198b
chr14_-_24123253 0.67 ENSRNOT00000002743
transmembrane protease, serine 11B
chr4_-_51199570 0.64 ENSRNOT00000010788
solute carrier family 13 member 1
chr2_+_85305225 0.64 ENSRNOT00000015904
taste receptor, type 2, member 119
chr3_-_114251647 0.63 ENSRNOT00000024245
dual oxidase maturation factor 1
chrX_+_37329779 0.61 ENSRNOT00000038352
ENSRNOT00000088802
pyruvate dehydrogenase (lipoamide) alpha 1
chr5_-_28164326 0.60 ENSRNOT00000088165
solute carrier family 26 member 7
chr8_+_18795525 0.60 ENSRNOT00000050430
olfactory receptor 1124
chr3_+_102947730 0.58 ENSRNOT00000071260
olfactory receptor 773
chr9_+_10013854 0.57 ENSRNOT00000077653
ENSRNOT00000072033
KH-type splicing regulatory protein
chr14_-_6533524 0.56 ENSRNOT00000079795
ATP-binding cassette, subfamily G (WHITE), member 3-like 1
chr14_+_70164650 0.55 ENSRNOT00000004385
quinoid dihydropteridine reductase
chr2_+_187951344 0.54 ENSRNOT00000027123
signal sequence receptor, beta
chr9_+_95295701 0.54 ENSRNOT00000025045
UDP glucuronosyltransferase family 1 member A5
chr12_-_37538403 0.53 ENSRNOT00000001402
small nuclear ribonucleoprotein U11/U12 subunit 35
chr8_+_41336340 0.52 ENSRNOT00000072049
olfactory receptor 1225
chr3_+_72134731 0.51 ENSRNOT00000083592
yippee-like 4
chr7_-_15821927 0.49 ENSRNOT00000050658
similar to zinc finger protein 101
chr5_+_142986526 0.49 ENSRNOT00000012811
R-spondin 1
chr18_-_16543992 0.46 ENSRNOT00000036306
solute carrier family 39 member 6
chr9_+_15513063 0.44 ENSRNOT00000020499
TATA-box binding protein associated factor 8

Network of associatons between targets according to the STRING database.

First level regulatory network of Gsx2_Hoxd3_Vax1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 18.9 GO:0051684 maintenance of Golgi location(GO:0051684)
4.3 12.9 GO:0051867 general adaptation syndrome, behavioral process(GO:0051867)
4.0 12.0 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
2.9 8.8 GO:2001055 embryonic nail plate morphogenesis(GO:0035880) positive regulation of mesenchymal cell apoptotic process(GO:2001055)
2.9 11.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
2.6 7.9 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
2.3 18.0 GO:0015884 folic acid transport(GO:0015884)
2.0 6.1 GO:0018199 peptidyl-glutamine modification(GO:0018199)
1.8 5.5 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
1.8 5.3 GO:0001905 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
1.5 4.6 GO:0048372 lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378) regulation of cardiac ventricle development(GO:1904412)
1.5 7.4 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
1.4 5.6 GO:1904009 cellular response to monosodium glutamate(GO:1904009)
1.4 7.0 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
1.4 5.5 GO:0052422 modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422) regulation of exo-alpha-sialidase activity(GO:1903015)
1.3 7.6 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
1.3 3.8 GO:1900222 regulation of cell growth by extracellular stimulus(GO:0001560) negative regulation of beta-amyloid clearance(GO:1900222) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
1.2 3.7 GO:1903595 pancreatic amylase secretion(GO:0036395) regulation of pancreatic amylase secretion(GO:1902276) positive regulation of histamine secretion by mast cell(GO:1903595)
1.2 4.6 GO:0035926 chemokine (C-C motif) ligand 2 secretion(GO:0035926)
1.0 5.2 GO:0061743 motor learning(GO:0061743)
1.0 3.0 GO:0006589 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
1.0 3.9 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.9 4.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.7 3.5 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.7 2.7 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.6 4.3 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.6 4.2 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.6 2.3 GO:0043179 rhythmic excitation(GO:0043179)
0.6 1.7 GO:0033306 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.5 1.6 GO:0042125 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.5 2.1 GO:0060327 cytoplasmic actin-based contraction involved in cell motility(GO:0060327)
0.5 6.7 GO:0099562 maintenance of postsynaptic specialization structure(GO:0098880) maintenance of postsynaptic density structure(GO:0099562)
0.5 3.0 GO:0042908 xenobiotic transport(GO:0042908)
0.5 2.4 GO:0045218 zonula adherens maintenance(GO:0045218)
0.4 3.9 GO:0070417 cellular response to cold(GO:0070417)
0.4 2.8 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.4 5.9 GO:0048733 sebaceous gland development(GO:0048733)
0.4 1.2 GO:0032978 protein insertion into membrane from inner side(GO:0032978)
0.4 1.2 GO:0016598 protein arginylation(GO:0016598)
0.4 2.7 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.4 11.6 GO:0006829 zinc II ion transport(GO:0006829)
0.4 4.5 GO:0001778 plasma membrane repair(GO:0001778)
0.4 1.5 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.4 6.3 GO:0032060 bleb assembly(GO:0032060)
0.3 3.4 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.3 2.3 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.3 3.4 GO:0015747 urate transport(GO:0015747)
0.3 8.6 GO:0097352 autophagosome maturation(GO:0097352)
0.3 11.1 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.3 29.8 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.3 1.5 GO:0051775 response to redox state(GO:0051775)
0.2 3.0 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.2 2.6 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.2 1.8 GO:0006776 vitamin A metabolic process(GO:0006776)
0.2 4.5 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.2 1.9 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.2 24.6 GO:0035690 cellular response to drug(GO:0035690)
0.2 30.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 0.6 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.2 3.0 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.2 1.3 GO:0051081 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.2 1.6 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.2 0.7 GO:0072709 cellular response to sorbitol(GO:0072709)
0.2 1.7 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.2 2.5 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.2 3.8 GO:0006825 copper ion transport(GO:0006825)
0.2 2.1 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.2 4.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 2.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 1.2 GO:0006670 sphingosine metabolic process(GO:0006670)
0.1 3.8 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.1 3.8 GO:0001556 oocyte maturation(GO:0001556)
0.1 2.5 GO:0060285 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.1 1.8 GO:0051639 actin filament network formation(GO:0051639)
0.1 6.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 8.6 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 1.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 1.3 GO:0034063 stress granule assembly(GO:0034063)
0.1 2.1 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.1 0.6 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.1 2.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.8 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 4.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.3 GO:1904742 protein poly-ADP-ribosylation(GO:0070212) regulation of telomeric DNA binding(GO:1904742)
0.1 1.9 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 0.9 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 0.6 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.1 1.5 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.1 11.1 GO:0042552 myelination(GO:0042552)
0.1 1.2 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.1 0.4 GO:0034227 tRNA thio-modification(GO:0034227)
0.1 2.7 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.1 1.3 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 0.5 GO:2000254 regulation of male germ cell proliferation(GO:2000254)
0.1 4.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.5 GO:0052697 xenobiotic glucuronidation(GO:0052697)
0.1 0.9 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.1 1.0 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.1 0.8 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 4.7 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.1 2.3 GO:0048662 negative regulation of smooth muscle cell proliferation(GO:0048662)
0.0 0.4 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 22.9 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.0 3.8 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.6 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 5.9 GO:0006865 amino acid transport(GO:0006865)
0.0 0.9 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.3 GO:0090042 tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043)
0.0 4.0 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.5 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.2 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 1.9 GO:0048278 vesicle docking(GO:0048278)
0.0 2.5 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 2.3 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 0.9 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.4 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.7 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.1 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 3.0 GO:0006006 glucose metabolic process(GO:0006006)
0.0 1.0 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 3.2 GO:0030031 cell projection assembly(GO:0030031)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 12.9 GO:0032280 symmetric synapse(GO:0032280)
1.2 11.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
1.2 3.7 GO:0035577 azurophil granule membrane(GO:0035577)
1.2 4.7 GO:0031021 interphase microtubule organizing center(GO:0031021)
1.0 17.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.8 3.9 GO:1990716 axonemal central apparatus(GO:1990716)
0.8 12.4 GO:0005883 neurofilament(GO:0005883)
0.8 5.3 GO:0005579 membrane attack complex(GO:0005579)
0.7 3.0 GO:0034774 secretory granule lumen(GO:0034774)
0.7 2.7 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.6 3.9 GO:0033093 Weibel-Palade body(GO:0033093)
0.5 2.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.5 11.1 GO:0005922 connexon complex(GO:0005922)
0.3 2.4 GO:0036449 microtubule minus-end(GO:0036449)
0.3 6.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.3 2.3 GO:0031209 SCAR complex(GO:0031209)
0.3 8.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 1.7 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 32.8 GO:0001650 fibrillar center(GO:0001650)
0.2 0.6 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 3.0 GO:0031045 dense core granule(GO:0031045)
0.2 2.7 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 1.6 GO:0031143 pseudopodium(GO:0031143)
0.1 2.9 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 9.9 GO:0031526 brush border membrane(GO:0031526)
0.1 0.4 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.1 12.9 GO:0005901 caveola(GO:0005901)
0.1 1.8 GO:0033391 chromatoid body(GO:0033391)
0.1 5.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.5 GO:0000243 commitment complex(GO:0000243)
0.1 4.2 GO:0034707 chloride channel complex(GO:0034707)
0.1 1.8 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 4.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 5.0 GO:0016459 myosin complex(GO:0016459)
0.1 0.9 GO:0034709 methylosome(GO:0034709)
0.1 4.8 GO:0005581 collagen trimer(GO:0005581)
0.1 4.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 14.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 2.3 GO:0045171 intercellular bridge(GO:0045171)
0.1 29.1 GO:0031012 extracellular matrix(GO:0031012)
0.1 1.8 GO:0005771 multivesicular body(GO:0005771)
0.1 19.4 GO:0015629 actin cytoskeleton(GO:0015629)
0.1 0.3 GO:0000125 PCAF complex(GO:0000125)
0.1 2.4 GO:0031201 SNARE complex(GO:0031201)
0.0 1.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 13.5 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 1.9 GO:0005844 polysome(GO:0005844)
0.0 1.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 6.3 GO:0070382 exocytic vesicle(GO:0070382)
0.0 1.7 GO:0042734 presynaptic membrane(GO:0042734)
0.0 22.3 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.9 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 7.1 GO:0030424 axon(GO:0030424)
0.0 7.0 GO:0016607 nuclear speck(GO:0016607)
0.0 0.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 1.6 GO:0005741 mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968)
0.0 2.9 GO:0005769 early endosome(GO:0005769)
0.0 4.2 GO:0005874 microtubule(GO:0005874)
0.0 1.1 GO:0000502 proteasome complex(GO:0000502)
0.0 9.1 GO:0005789 endoplasmic reticulum membrane(GO:0005789)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 11.5 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
2.3 18.0 GO:0008517 folic acid transporter activity(GO:0008517)
2.2 12.9 GO:0001515 opioid peptide activity(GO:0001515)
1.4 5.6 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
1.1 29.8 GO:0043014 alpha-tubulin binding(GO:0043014)
1.1 7.9 GO:0031852 mu-type opioid receptor binding(GO:0031852)
1.0 3.0 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.8 5.0 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.8 24.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.8 5.5 GO:0001849 complement component C1q binding(GO:0001849)
0.8 4.6 GO:0098821 BMP receptor activity(GO:0098821)
0.7 2.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.7 7.0 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.7 2.7 GO:0019002 GMP binding(GO:0019002)
0.7 4.7 GO:0045503 dynein light chain binding(GO:0045503)
0.6 6.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.6 3.0 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.5 4.3 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.5 6.7 GO:0098879 structural constituent of postsynaptic specialization(GO:0098879) structural constituent of postsynaptic density(GO:0098919)
0.5 2.5 GO:0019770 IgG receptor activity(GO:0019770)
0.5 11.1 GO:0002162 dystroglycan binding(GO:0002162)
0.4 1.7 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.4 7.4 GO:0044548 S100 protein binding(GO:0044548)
0.4 1.6 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.4 1.2 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.4 1.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.4 1.6 GO:0015057 thrombin receptor activity(GO:0015057)
0.4 2.6 GO:0001595 angiotensin receptor activity(GO:0001595)
0.4 2.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.3 3.4 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.3 3.0 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.3 5.5 GO:0005523 tropomyosin binding(GO:0005523)
0.3 3.8 GO:0033691 sialic acid binding(GO:0033691)
0.3 6.0 GO:0017081 chloride channel regulator activity(GO:0017081)
0.3 1.9 GO:1990715 mRNA CDS binding(GO:1990715)
0.3 4.3 GO:0016805 dipeptidase activity(GO:0016805)
0.3 1.7 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.3 1.6 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.3 3.8 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.3 3.3 GO:0019841 retinol binding(GO:0019841)
0.2 2.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.2 57.8 GO:0005096 GTPase activator activity(GO:0005096)
0.2 7.6 GO:0005109 frizzled binding(GO:0005109)
0.2 1.8 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.2 2.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 2.9 GO:0050811 GABA receptor binding(GO:0050811)
0.2 3.9 GO:0019865 immunoglobulin binding(GO:0019865)
0.2 0.6 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.2 1.5 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 3.0 GO:0042056 chemoattractant activity(GO:0042056)
0.1 3.8 GO:0070412 R-SMAD binding(GO:0070412)
0.1 12.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.6 GO:0070404 NADH binding(GO:0070404)
0.1 1.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 2.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.1 4.5 GO:0004601 peroxidase activity(GO:0004601)
0.1 3.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 6.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 2.8 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.3 GO:0005521 lamin binding(GO:0005521)
0.1 1.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 1.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 7.0 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 0.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.4 GO:0003840 gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.1 2.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 2.1 GO:0004180 carboxypeptidase activity(GO:0004180)
0.1 2.7 GO:0070888 E-box binding(GO:0070888)
0.1 0.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 2.0 GO:0070330 aromatase activity(GO:0070330)
0.0 1.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.6 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.9 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 1.0 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 4.0 GO:0051015 actin filament binding(GO:0051015)
0.0 5.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 4.2 GO:0044325 ion channel binding(GO:0044325)
0.0 1.3 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.6 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 9.3 GO:0046873 metal ion transmembrane transporter activity(GO:0046873)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.7 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 9.1 GO:0005509 calcium ion binding(GO:0005509)
0.0 3.5 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.9 GO:0019003 GDP binding(GO:0019003)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 2.1 GO:0000287 magnesium ion binding(GO:0000287)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 24.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.3 27.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.2 6.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.2 5.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2 11.3 PID LKB1 PATHWAY LKB1 signaling events
0.2 11.8 PID AP1 PATHWAY AP-1 transcription factor network
0.1 7.4 PID FGF PATHWAY FGF signaling pathway
0.1 6.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 5.6 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.1 0.7 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 1.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 4.7 PID BMP PATHWAY BMP receptor signaling
0.1 1.6 ST GA12 PATHWAY G alpha 12 Pathway
0.1 4.5 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 1.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 1.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 1.8 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 1.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 3.8 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 2.2 PID P53 REGULATION PATHWAY p53 pathway
0.0 7.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.3 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.6 PID TNF PATHWAY TNF receptor signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 29.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.6 7.4 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.4 7.0 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.3 4.5 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.3 17.4 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.3 3.9 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.3 3.0 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 5.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 5.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.2 3.0 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.2 3.7 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.2 5.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 4.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 17.6 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 0.9 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 4.2 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 1.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.8 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 1.8 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 2.1 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 1.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 4.1 REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.1 1.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 2.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.7 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 1.9 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 3.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation