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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Gsx1_Alx1_Mixl1_Lbx2

Z-value: 0.93

Motif logo

Transcription factors associated with Gsx1_Alx1_Mixl1_Lbx2

Gene Symbol Gene ID Gene Info
ENSRNOG00000000952 GS homeobox 1
ENSRNOG00000004390 ALX homeobox 1
ENSRNOG00000003176 Mix paired-like homeobox 1
ENSRNOG00000052374 ladybird homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mixl1rn6_v1_chr13_-_97282299_972822990.382.6e-12Click!
Alx1rn6_v1_chr7_-_44771458_44771458-0.342.4e-10Click!
Gsx1rn6_v1_chr12_-_9607168_96071680.241.5e-05Click!
Lbx2rn6_v1_chr4_+_113918740_1139187400.107.1e-02Click!

Activity profile of Gsx1_Alx1_Mixl1_Lbx2 motif

Sorted Z-values of Gsx1_Alx1_Mixl1_Lbx2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_118197217 72.40 ENSRNOT00000090922
5-hydroxytryptamine receptor 2C
chr9_-_30844199 68.45 ENSRNOT00000017169
collagen type XIX alpha 1 chain
chr12_-_2174131 54.66 ENSRNOT00000001313
Purkinje cell protein 2
chr11_+_58624198 46.11 ENSRNOT00000002091
growth associated protein 43
chr4_-_55011415 43.40 ENSRNOT00000056996
glutamate metabotropic receptor 8
chr1_+_198383201 39.90 ENSRNOT00000037405
seizure related 6 homolog like 2
chr9_+_73418607 38.93 ENSRNOT00000092547
microtubule-associated protein 2
chr13_-_76049363 36.29 ENSRNOT00000075865
ENSRNOT00000007455
BMP/retinoic acid inducible neural specific 2
chr7_-_28711761 35.10 ENSRNOT00000006249
PARP1 binding protein
chr17_-_43807540 32.89 ENSRNOT00000074763
similar to CG31613-PA
chr1_-_215033460 32.01 ENSRNOT00000044565
dual specificity phosphatase 8
chr8_-_84506328 30.86 ENSRNOT00000064754
muscular LMNA-interacting protein
chr4_+_94696965 29.89 ENSRNOT00000064696
glutamate ionotropic receptor delta type subunit 2
chr9_-_85243001 29.34 ENSRNOT00000020219
secretogranin II
chr2_-_35104963 27.78 ENSRNOT00000018058
regulator of G-protein signaling 7-binding protein
chr15_-_95514259 26.66 ENSRNOT00000038433
SLIT and NTRK-like family, member 6
chr7_+_78558701 25.62 ENSRNOT00000006393
regulating synaptic membrane exocytosis 2
chr2_+_66940057 24.58 ENSRNOT00000043050
cadherin 9
chr17_+_47721977 24.41 ENSRNOT00000080800
amphiphysin-like
chr2_-_188559882 23.54 ENSRNOT00000088199
tripartite motif-containing 46
chr12_-_35979193 23.11 ENSRNOT00000071104
transmembrane protein 132B
chr2_-_57935334 22.27 ENSRNOT00000022319
ENSRNOT00000085599
ENSRNOT00000077790
ENSRNOT00000035821
solute carrier family 1 member 3
chr3_-_66417741 21.73 ENSRNOT00000007662
neuronal differentiation 1
chrX_+_84064427 21.25 ENSRNOT00000046364
zinc finger protein 711
chr5_-_17061837 20.86 ENSRNOT00000011892
proenkephalin
chr6_-_114476723 20.56 ENSRNOT00000005162
deiodinase, iodothyronine, type II
chr3_-_51612397 18.43 ENSRNOT00000081401
sodium voltage-gated channel alpha subunit 3
chr4_-_17594598 18.21 ENSRNOT00000008936
semaphorin 3E
chr11_-_4332255 17.90 ENSRNOT00000087133
cell adhesion molecule 2
chr4_-_157304653 17.72 ENSRNOT00000051613
leucine rich repeat containing 23
chr8_+_97291580 17.59 ENSRNOT00000018794
RAS protein-specific guanine nucleotide-releasing factor 1
chr8_+_122076759 17.44 ENSRNOT00000012545
cytoplasmic linker associated protein 2
chr10_-_74679858 17.24 ENSRNOT00000003859
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr5_-_17061361 17.09 ENSRNOT00000089318
proenkephalin
chr8_+_33239139 16.64 ENSRNOT00000011589
Rho GTPase activating protein 32
chr2_+_72006099 15.84 ENSRNOT00000034044
cadherin 12
chr4_+_158088505 15.54 ENSRNOT00000026643
von Willebrand factor
chr12_-_5682608 14.81 ENSRNOT00000076483
FRY microtubule binding protein
chr2_-_219262901 14.62 ENSRNOT00000037068
G-protein coupled receptor 88
chr8_-_120446455 14.43 ENSRNOT00000085161
ENSRNOT00000042854
ENSRNOT00000037199
cAMP regulated phosphoprotein 21
chr7_+_44009069 14.13 ENSRNOT00000005523
MGAT4 family, member C
chr10_-_66848388 14.10 ENSRNOT00000018891
oligodendrocyte-myelin glycoprotein
chr15_+_56666012 13.97 ENSRNOT00000013408
5-hydroxytryptamine receptor 2A
chr2_-_265300868 13.74 ENSRNOT00000066024
ENSRNOT00000016073
ENSRNOT00000033502
leucine rich repeat containing 7
chr2_-_256154584 13.70 ENSRNOT00000072487

chrX_+_62727755 13.02 ENSRNOT00000077055
phosphate cytidylyltransferase 1, choline, beta
chr16_-_73152921 12.97 ENSRNOT00000048602
zinc finger, matrin type 4
chr5_-_12526962 12.89 ENSRNOT00000092104
suppression of tumorigenicity 18
chr10_-_87248572 12.76 ENSRNOT00000066637
ENSRNOT00000085677
keratin 26
chrX_+_65040934 12.43 ENSRNOT00000044006
zinc finger CCCH-type containing 12B
chr14_+_37116492 12.20 ENSRNOT00000002921
sarcoglycan, beta
chr15_+_1054937 12.12 ENSRNOT00000008154

chr13_-_32427177 11.98 ENSRNOT00000044628
cadherin 19
chr2_+_198417619 11.86 ENSRNOT00000085945
histone cluster 2, H3c2
chr10_+_55940533 11.75 ENSRNOT00000012061
similar to RIKEN cDNA A030009H04
chr8_+_104106740 11.71 ENSRNOT00000015015
transcription factor Dp-2
chrX_+_131381134 11.65 ENSRNOT00000007474

chr7_+_28654733 11.56 ENSRNOT00000006174
pro-melanin-concentrating hormone
chr4_+_33638709 11.48 ENSRNOT00000009888
ENSRNOT00000034719
ENSRNOT00000052333
tachykinin, precursor 1
chr4_-_119327822 11.45 ENSRNOT00000012645
Rho GTPase activating protein 25
chr3_+_173799833 11.44 ENSRNOT00000081235
phosphatase and actin regulator 3
chr3_-_52447622 11.43 ENSRNOT00000083552
sodium voltage-gated channel alpha subunit 1
chr9_-_11027506 11.37 ENSRNOT00000071107
chromatin assembly factor 1 subunit A
chr11_-_4397361 11.27 ENSRNOT00000046370
cell adhesion molecule 2
chr3_+_48106099 11.03 ENSRNOT00000007218
solute carrier family 4 member 10
chr18_+_62852303 11.01 ENSRNOT00000087673
G protein subunit alpha L
chrX_+_65040775 11.00 ENSRNOT00000081354
zinc finger CCCH-type containing 12B
chr15_-_93748742 10.87 ENSRNOT00000093370
MYC binding protein 2, E3 ubiquitin protein ligase
chr18_-_24057917 10.80 ENSRNOT00000023874
Ras-like without CAAX 2
chr18_-_67224566 10.60 ENSRNOT00000064947
DCC netrin 1 receptor
chr3_-_151032302 10.55 ENSRNOT00000025315
gamma-glutamyltransferase 7
chr2_-_170301348 10.49 ENSRNOT00000088131
sucrase-isomaltase
chr6_+_73553210 10.46 ENSRNOT00000006562
A-kinase anchoring protein 6
chr10_-_87232723 10.36 ENSRNOT00000015150
keratin 25
chr13_-_90405591 10.19 ENSRNOT00000006849
VANGL planar cell polarity protein 2
chr13_-_111581018 10.18 ENSRNOT00000083072
ENSRNOT00000077981
SERTA domain containing 4
chr1_+_240355149 10.14 ENSRNOT00000018521
transient receptor potential cation channel, subfamily M, member 3
chr3_+_110855000 10.14 ENSRNOT00000081613
kinetochore scaffold 1
chr9_+_20241062 10.06 ENSRNOT00000071593
leucine-rich repeat-containing protein 23-like
chr2_-_139528162 9.99 ENSRNOT00000014317
solute carrier family 7 member 11
chr7_+_42269784 9.91 ENSRNOT00000008471
ENSRNOT00000007231
KIT ligand
chr1_+_8310577 9.86 ENSRNOT00000015131
human immunodeficiency virus type I enhancer binding protein 2
chr7_-_73130740 9.57 ENSRNOT00000075584
RIKEN cDNA 9430069I07 gene
chr11_-_43022565 9.42 ENSRNOT00000002285
ribosomal oxygenase 2
chr5_-_168734296 9.32 ENSRNOT00000066120
calmodulin binding transcription activator 1
chr7_-_143353925 9.17 ENSRNOT00000068533
keratin 71
chr18_-_6781841 9.16 ENSRNOT00000077606
ENSRNOT00000048109
aquaporin 4
chr19_+_39229754 9.14 ENSRNOT00000050612
vacuolar protein sorting 4 homolog A
chr2_-_231648122 9.02 ENSRNOT00000014962
ankyrin 2
chr1_-_43638161 9.01 ENSRNOT00000024460
interaction protein for cytohesin exchange factors 1
chr3_+_128828331 8.91 ENSRNOT00000045393
phospholipase C, beta 4
chr5_+_139790395 8.77 ENSRNOT00000015033
regulating synaptic membrane exocytosis 3
chr4_+_138441332 8.71 ENSRNOT00000090847
contactin 4
chr17_+_44794130 8.63 ENSRNOT00000077571
histone cluster 1, H2ac
chr9_+_10941613 8.42 ENSRNOT00000070794
semaphorin 6B
chr8_+_102304095 8.27 ENSRNOT00000011358
solute carrier family 9 member A9
chr10_+_66942398 8.16 ENSRNOT00000018986
RAB11 family interacting protein 4
chr17_+_24416651 8.03 ENSRNOT00000024458
CD83 molecule
chr11_-_11585078 7.98 ENSRNOT00000088878
roundabout guidance receptor 2
chr6_+_22696397 7.88 ENSRNOT00000011630
anaplastic lymphoma receptor tyrosine kinase
chrX_-_124464963 7.72 ENSRNOT00000036472
ENSRNOT00000077697
transmembrane protein 255A
chr7_+_133856101 7.70 ENSRNOT00000038686
PDZ domain containing RING finger 4
chr2_-_96509424 7.66 ENSRNOT00000090866
zinc finger, C2HC-type containing 1A
chr3_-_26056818 7.64 ENSRNOT00000044209
LDL receptor related protein 1B
chrX_+_6273733 7.63 ENSRNOT00000074275
NDP, norrin cystine knot growth factor
chr1_-_48825364 7.48 ENSRNOT00000024213
1-acylglycerol-3-phosphate O-acyltransferase 4
chr5_+_10178302 7.46 ENSRNOT00000009679
syntrophin, gamma 1
chr13_-_82005741 7.41 ENSRNOT00000076404
methyltransferase like 11B
chr5_+_18901039 7.31 ENSRNOT00000012066
family with sequence similarity 110, member B
chr10_-_16731898 7.25 ENSRNOT00000028186
CREB3 regulatory factor
chr5_+_133819726 7.24 ENSRNOT00000081075
Scl/Tal1 interrupting locus
chr7_+_136182224 7.16 ENSRNOT00000008159
transmembrane protein 117
chr7_+_2752680 7.14 ENSRNOT00000033726
citrate synthase
chr13_-_51992693 7.14 ENSRNOT00000008282
G protein-coupled receptor 37-like 1
chrX_+_158835811 7.14 ENSRNOT00000071888
ENSRNOT00000080110
integrator complex subunit 6 like
chr8_-_39551700 7.11 ENSRNOT00000091894
ENSRNOT00000076025
PBX/knotted 1 homeobox 2
chr7_-_107616038 7.08 ENSRNOT00000088752
src-like adaptor
chr20_+_27366213 7.08 ENSRNOT00000000302
ENSRNOT00000057939
tet methylcytosine dioxygenase 1
chr13_-_107886476 7.04 ENSRNOT00000077282
potassium two pore domain channel subfamily K member 2
chr13_-_82006005 7.00 ENSRNOT00000039581
methyltransferase like 11B
chrX_+_40460047 6.99 ENSRNOT00000010970
phosphate regulating endopeptidase homolog, X-linked
chr20_+_3830164 6.98 ENSRNOT00000045533
ENSRNOT00000084117
collagen type XI alpha 2 chain
chr18_+_31444472 6.96 ENSRNOT00000075159
ring finger protein 14
chr11_+_13499164 6.95 ENSRNOT00000013159
similar to heat shock protein 8
chr3_-_15278645 6.92 ENSRNOT00000032204
tubulin tyrosine ligase like11
chr19_+_25043680 6.90 ENSRNOT00000043971
adhesion G protein-coupled receptor L1
chr3_+_177310753 6.80 ENSRNOT00000031448
myelin transcription factor 1
chr9_+_60039297 6.77 ENSRNOT00000016262
solute carrier family 39 member 10
chr13_+_78979321 6.75 ENSRNOT00000003857
ankyrin repeat domain 45
chr15_+_4209703 6.71 ENSRNOT00000082236
protein phosphatase 3 catalytic subunit beta
chr3_-_25212049 6.69 ENSRNOT00000040023
LDL receptor related protein 1B
chr7_-_15073052 6.65 ENSRNOT00000037708
zinc finger protein 799
chr18_+_65285318 6.64 ENSRNOT00000020431
transcription factor 4
chr5_-_9035811 6.56 ENSRNOT00000082023
minichromosome maintenance domain containing 2
chr8_-_33121002 6.56 ENSRNOT00000047211
LRRGT00010-like
chr7_+_121841855 6.52 ENSRNOT00000024673
GRB2-related adaptor protein 2
chr5_+_122019301 6.51 ENSRNOT00000068158
phosphodiesterase 4B
chrX_-_104932508 6.47 ENSRNOT00000075325
NADPH oxidase 1
chr8_+_23193181 6.43 ENSRNOT00000071703
zinc finger protein 872
chr14_+_91782354 6.42 ENSRNOT00000005902
IKAROS family zinc finger 1
chr12_-_46493203 6.41 ENSRNOT00000057036
citron rho-interacting serine/threonine kinase
chr19_+_6046665 6.37 ENSRNOT00000084126
cadherin 8
chr1_-_120893997 6.36 ENSRNOT00000081028

chr10_-_91986632 6.33 ENSRNOT00000087824
N-ethylmaleimide sensitive factor, vesicle fusing ATPase
chr17_-_43798383 6.14 ENSRNOT00000075069
similar to Histone H1.2 (H1 VAR.1) (H1c)
chr3_-_90751055 6.14 ENSRNOT00000040741
LRRGT00091
chr6_-_115513354 6.07 ENSRNOT00000005881
stonin 2
chr14_-_45859908 5.98 ENSRNOT00000086994
phosphoglucomutase 2
chr7_-_76488216 5.91 ENSRNOT00000080024
neurocalcin delta
chr4_-_180234804 5.74 ENSRNOT00000070957
basic helix-loop-helix family, member e41
chr18_-_53181503 5.73 ENSRNOT00000066548
fibrillin 2
chr1_+_105284753 5.71 ENSRNOT00000041950
solute carrier family 6 member 5
chr3_-_111080705 5.70 ENSRNOT00000079339
ras homolog family member V
chr13_-_102942863 5.65 ENSRNOT00000003198
microtubule affinity regulating kinase 1
chr7_+_144865608 5.63 ENSRNOT00000091596
ENSRNOT00000055285
heterogeneous nuclear ribonucleoprotein A1
chr15_+_87722221 5.63 ENSRNOT00000082688
sciellin
chr19_-_24614019 5.59 ENSRNOT00000005124
short coiled-coil protein
chr17_+_11683862 5.56 ENSRNOT00000024766
msh homeobox 2
chrX_+_159158194 5.55 ENSRNOT00000043820
ENSRNOT00000001169
ENSRNOT00000083502
four and a half LIM domains 1
chr11_+_46737892 5.52 ENSRNOT00000052182

chr4_+_180291389 5.50 ENSRNOT00000002465
sarcospan
chr17_-_61332391 5.47 ENSRNOT00000034599
SNRPN upstream reading frame protein-like
chrX_+_105147534 5.46 ENSRNOT00000046288
centromere protein I
chr4_-_168656673 5.43 ENSRNOT00000009341
G protein-coupled receptor 19
chr1_+_13261876 5.36 ENSRNOT00000090703
RALBP1 associated Eps domain containing 1
chr18_+_16544508 5.35 ENSRNOT00000020601
elongator acetyltransferase complex subunit 2
chr14_+_104250617 5.31 ENSRNOT00000079874
sprouty-related, EVH1 domain containing 2
chr18_-_16542165 5.22 ENSRNOT00000079381
solute carrier family 39 member 6
chr3_+_47677720 5.22 ENSRNOT00000065340
T-box, brain, 1
chr2_+_18354542 5.21 ENSRNOT00000042958
hyaluronan and proteoglycan link protein 1
chr15_+_31950986 5.19 ENSRNOT00000080233

chr1_-_124803363 5.16 ENSRNOT00000066380
Kruppel-like factor 13
chr2_+_22950018 5.13 ENSRNOT00000071804
homer scaffolding protein 1
chr12_+_41486076 5.12 ENSRNOT00000057242
RBPJ interacting and tubulin associated 1
chr8_+_71514281 5.07 ENSRNOT00000022256
NS5A (hepatitis C virus) transactivated protein 9
chrX_-_29556610 5.07 ENSRNOT00000068113
trafficking protein particle complex 2
chrX_-_72034099 4.97 ENSRNOT00000004310
ERCC excision repair 6 like, spindle assembly checkpoint helicase
chr15_+_12827707 4.88 ENSRNOT00000012452
Fez family zinc finger 2
chr17_+_43632397 4.86 ENSRNOT00000013790
histone cluster 1, H2ah
chr14_+_66631690 4.84 ENSRNOT00000079658
potassium voltage-gated channel interacting protein 4
chr15_-_37831031 4.81 ENSRNOT00000091562
eukaryotic translation elongation factor 1 alpha lysine methyltransferase 1
chr9_-_53315915 4.80 ENSRNOT00000038093
myostatin
chr1_+_140792049 4.79 ENSRNOT00000049681
aggrecan
chr5_-_7941822 4.70 ENSRNOT00000079917
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr2_-_250923744 4.68 ENSRNOT00000084996
chloride channel accessory 1
chr16_+_10417185 4.67 ENSRNOT00000082186
annexin A8
chrX_+_92131209 4.65 ENSRNOT00000004462
poly A binding protein, cytoplasmic 5
chr4_+_22898527 4.63 ENSRNOT00000072455
ENSRNOT00000076123
DBF4 zinc finger
chr7_-_104801045 4.63 ENSRNOT00000079524
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr1_+_15834779 4.60 ENSRNOT00000079069
ENSRNOT00000083012
BCL2-associated transcription factor 1
chr18_+_30023828 4.55 ENSRNOT00000079008
protocadherin alpha 4
chr12_+_47551935 4.54 ENSRNOT00000056932
RGD1560398
chr1_-_38586563 4.54 ENSRNOT00000070999
ENSRNOT00000071758
similar to regulator of sex-limitation candidate 1
chr2_-_58534211 4.47 ENSRNOT00000089178
S-phase kinase associated protein 2
chr2_-_38110567 4.41 ENSRNOT00000072212
importin 11
chr8_-_83280888 4.37 ENSRNOT00000052341
GDNF family receptor alpha like
chr17_-_43640387 4.33 ENSRNOT00000087731
histone cluster 1 H1 family member c
chr10_+_1834518 4.31 ENSRNOT00000061709
predicted gene 1758
chr10_-_67401836 4.28 ENSRNOT00000073071
cytokine receptor-like factor 3
chr18_+_29960072 4.27 ENSRNOT00000071366

Network of associatons between targets according to the STRING database.

First level regulatory network of Gsx1_Alx1_Mixl1_Lbx2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
28.8 86.4 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
12.7 38.0 GO:0051867 general adaptation syndrome, behavioral process(GO:0051867)
6.5 52.0 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
5.6 22.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
5.4 54.1 GO:0016198 axon choice point recognition(GO:0016198)
5.3 26.7 GO:0060005 vestibular reflex(GO:0060005)
4.8 14.4 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
4.3 21.7 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
3.9 43.4 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
3.7 14.8 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
3.5 35.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
3.4 10.2 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
3.2 6.5 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
3.0 9.1 GO:1903774 multivesicular body assembly(GO:0036258) positive regulation of viral budding via host ESCRT complex(GO:1903774)
2.9 14.6 GO:0061743 motor learning(GO:0061743)
2.7 10.6 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
2.6 7.9 GO:0090648 response to environmental enrichment(GO:0090648)
2.6 10.5 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
2.4 7.3 GO:1902211 regulation of prolactin signaling pathway(GO:1902211)
2.4 7.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
2.3 7.0 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
2.3 7.0 GO:1904383 response to sodium phosphate(GO:1904383)
2.3 11.6 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
2.3 11.5 GO:0046878 positive regulation of saliva secretion(GO:0046878) positive regulation of glucocorticoid secretion(GO:2000851)
2.3 9.2 GO:0060354 negative regulation of cell adhesion molecule production(GO:0060354)
2.3 20.6 GO:0042447 hormone catabolic process(GO:0042447)
2.3 9.0 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
2.2 6.7 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
2.1 29.9 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
2.1 39.9 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
2.0 9.9 GO:0070668 negative regulation of mast cell apoptotic process(GO:0033026) mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
2.0 25.6 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
1.9 5.6 GO:0035880 embryonic nail plate morphogenesis(GO:0035880) positive regulation of catagen(GO:0051795) positive regulation of mesenchymal cell apoptotic process(GO:2001055)
1.8 18.4 GO:0046684 response to pyrethroid(GO:0046684)
1.8 10.8 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
1.7 17.4 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
1.7 15.5 GO:0070417 cellular response to cold(GO:0070417)
1.7 27.3 GO:0099612 protein localization to axon(GO:0099612)
1.7 10.1 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
1.6 14.5 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
1.6 6.4 GO:0045658 regulation of neutrophil differentiation(GO:0045658)
1.6 6.3 GO:0035494 SNARE complex disassembly(GO:0035494)
1.6 28.1 GO:0050930 induction of positive chemotaxis(GO:0050930)
1.4 13.0 GO:1904116 response to vasopressin(GO:1904116)
1.4 5.6 GO:1903936 cellular response to sodium arsenite(GO:1903936)
1.4 11.0 GO:0009405 pathogenesis(GO:0009405)
1.4 12.2 GO:0097084 vascular smooth muscle cell development(GO:0097084)
1.3 8.0 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
1.3 10.6 GO:0006751 glutathione catabolic process(GO:0006751)
1.3 6.6 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
1.3 10.5 GO:0016584 nucleosome positioning(GO:0016584)
1.3 3.9 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
1.3 7.6 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
1.2 2.4 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
1.2 25.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
1.2 7.0 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
1.2 7.0 GO:0060023 soft palate development(GO:0060023)
1.2 35.7 GO:0014741 negative regulation of muscle hypertrophy(GO:0014741)
1.1 8.0 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
1.1 5.7 GO:0071692 protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
1.1 38.9 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
1.1 5.7 GO:0036233 glycine import(GO:0036233)
1.1 3.3 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
1.1 12.0 GO:0071578 zinc II ion transmembrane import(GO:0071578)
1.0 3.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) protein K33-linked deubiquitination(GO:1990168)
1.0 15.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
1.0 3.0 GO:0015692 nickel cation transport(GO:0015675) vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) nickel cation transmembrane transport(GO:0035444)
1.0 17.6 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
1.0 2.9 GO:1903544 response to butyrate(GO:1903544)
1.0 2.9 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.9 9.4 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.9 2.8 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.9 12.1 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.9 25.1 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.9 10.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.9 3.6 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.9 7.2 GO:0033504 floor plate development(GO:0033504)
0.9 2.7 GO:2000721 regulation of cell growth by extracellular stimulus(GO:0001560) negative regulation of beta-amyloid clearance(GO:1900222) positive regulation of vascular smooth muscle cell differentiation(GO:1905065) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.9 3.4 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.8 3.4 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.8 7.5 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.8 7.1 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.8 4.7 GO:0032429 regulation of phospholipase A2 activity(GO:0032429)
0.8 2.3 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.7 10.5 GO:0034285 response to sucrose(GO:0009744) response to fructose(GO:0009750) response to disaccharide(GO:0034285)
0.7 4.5 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.7 1.5 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.7 4.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.7 19.5 GO:0045109 intermediate filament organization(GO:0045109)
0.7 10.0 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.7 6.9 GO:0018095 protein polyglutamylation(GO:0018095)
0.7 6.9 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.7 5.5 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.7 4.8 GO:0060591 chondroblast differentiation(GO:0060591)
0.7 10.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.6 11.0 GO:0021860 pyramidal neuron development(GO:0021860)
0.6 8.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.6 89.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.6 18.4 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.6 1.9 GO:0015808 L-alanine transport(GO:0015808)
0.6 3.1 GO:0043418 homocysteine catabolic process(GO:0043418)
0.6 3.6 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.6 1.8 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.6 6.9 GO:0001778 plasma membrane repair(GO:0001778)
0.6 5.7 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.6 2.9 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.6 5.6 GO:0061635 regulation of protein complex stability(GO:0061635)
0.6 6.6 GO:0042118 endothelial cell activation(GO:0042118)
0.5 14.1 GO:0048679 regulation of axon regeneration(GO:0048679)
0.5 36.3 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.5 2.1 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.5 37.5 GO:0006334 nucleosome assembly(GO:0006334)
0.5 5.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.5 1.0 GO:0051866 general adaptation syndrome(GO:0051866)
0.5 3.0 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.5 1.9 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.5 4.2 GO:0015816 glycine transport(GO:0015816)
0.5 2.3 GO:0006041 glucosamine metabolic process(GO:0006041)
0.5 4.1 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.5 2.3 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) glucosamine-containing compound catabolic process(GO:1901072)
0.5 3.2 GO:0045348 response to cobalamin(GO:0033590) positive regulation of MHC class II biosynthetic process(GO:0045348)
0.4 1.3 GO:0019086 late viral transcription(GO:0019086)
0.4 7.5 GO:0007602 phototransduction(GO:0007602)
0.4 0.9 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.4 0.9 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.4 4.2 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.4 7.1 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.4 4.0 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.4 3.9 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.4 3.9 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.4 1.5 GO:0051684 maintenance of Golgi location(GO:0051684)
0.4 2.6 GO:0070543 response to linoleic acid(GO:0070543)
0.4 1.5 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.4 2.2 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.4 2.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.4 2.9 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.3 1.0 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.3 2.4 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.3 8.8 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.3 5.4 GO:0043248 proteasome assembly(GO:0043248)
0.3 6.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.3 1.0 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.3 0.9 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.3 2.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.3 0.9 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.3 6.4 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.3 1.2 GO:0038110 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016) interleukin-2-mediated signaling pathway(GO:0038110)
0.3 1.5 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.3 3.3 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.3 1.5 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.3 1.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.3 7.0 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.3 3.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.3 0.8 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.3 1.5 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2 0.7 GO:0035928 mitochondrial mRNA catabolic process(GO:0000958) positive regulation of mitochondrial RNA catabolic process(GO:0000962) rRNA import into mitochondrion(GO:0035928) polyadenylation-dependent RNA catabolic process(GO:0043633)
0.2 2.0 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 1.4 GO:0032060 bleb assembly(GO:0032060)
0.2 1.6 GO:0097264 self proteolysis(GO:0097264)
0.2 1.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.2 2.0 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.2 3.5 GO:0032288 myelin assembly(GO:0032288)
0.2 0.8 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.2 4.4 GO:0016048 detection of temperature stimulus(GO:0016048)
0.2 5.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.2 9.9 GO:0034605 cellular response to heat(GO:0034605)
0.2 2.3 GO:0042048 olfactory behavior(GO:0042048)
0.2 0.4 GO:0045425 positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.2 2.3 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.2 3.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.2 1.9 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.2 1.5 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.2 2.4 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.2 2.6 GO:0032674 regulation of interleukin-5 production(GO:0032674)
0.2 4.1 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.2 12.5 GO:0006342 chromatin silencing(GO:0006342)
0.2 6.1 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.2 0.5 GO:1904618 transitional stage B cell differentiation(GO:0002332) transitional one stage B cell differentiation(GO:0002333) glomerular visceral epithelial cell apoptotic process(GO:1903210) regulation of actin filament binding(GO:1904529) positive regulation of actin filament binding(GO:1904531) regulation of actin binding(GO:1904616) positive regulation of actin binding(GO:1904618) activation of protein kinase C activity(GO:1990051)
0.2 9.3 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 2.8 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 7.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 2.3 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.1 3.1 GO:0060285 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.1 5.6 GO:0043268 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) positive regulation of potassium ion transport(GO:0043268)
0.1 1.4 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 4.4 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.1 3.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 1.9 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.1 1.2 GO:0071493 cellular response to UV-B(GO:0071493) response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 23.2 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.1 1.6 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 2.0 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 3.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 1.5 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 4.8 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.1 3.3 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 1.5 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 1.3 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 1.6 GO:0006517 protein deglycosylation(GO:0006517)
0.1 1.7 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.1 1.0 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.1 7.2 GO:2001022 positive regulation of response to DNA damage stimulus(GO:2001022)
0.1 9.7 GO:0030010 establishment of cell polarity(GO:0030010)
0.1 1.0 GO:0097435 fibril organization(GO:0097435)
0.1 3.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.2 GO:0060327 cytoplasmic actin-based contraction involved in cell motility(GO:0060327)
0.1 0.7 GO:0071625 vocalization behavior(GO:0071625)
0.1 0.4 GO:0034227 tRNA thio-modification(GO:0034227)
0.1 10.0 GO:0007411 axon guidance(GO:0007411)
0.1 0.4 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 3.1 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 4.2 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 4.7 GO:0008344 adult locomotory behavior(GO:0008344)
0.1 3.7 GO:0048278 vesicle docking(GO:0048278)
0.1 1.1 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.1 2.2 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 8.6 GO:0090068 positive regulation of cell cycle process(GO:0090068)
0.1 4.7 GO:0030216 keratinocyte differentiation(GO:0030216)
0.1 1.2 GO:0045116 protein neddylation(GO:0045116)
0.1 2.0 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.1 5.0 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.1 2.1 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.1 0.7 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.1 6.4 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.3 GO:0007379 segment specification(GO:0007379)
0.0 0.1 GO:0038001 paracrine signaling(GO:0038001)
0.0 0.7 GO:1901099 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 1.3 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 2.5 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.0 1.7 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 1.6 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 3.3 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 2.8 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.8 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 1.3 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 3.0 GO:0007409 axonogenesis(GO:0007409)
0.0 0.9 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.6 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 1.6 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.0 1.2 GO:0042100 B cell proliferation(GO:0042100)
0.0 1.1 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 1.1 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.6 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 0.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 2.1 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 1.9 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.9 GO:0048041 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041)
0.0 1.2 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 1.5 GO:0000724 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 7.7 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.9 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.4 GO:0001658 branching involved in ureteric bud morphogenesis(GO:0001658)
0.0 0.6 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 2.2 GO:0010976 positive regulation of neuron projection development(GO:0010976)
0.0 0.7 GO:0030901 midbrain development(GO:0030901)
0.0 0.1 GO:0090083 regulation of inclusion body assembly(GO:0090083)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
7.1 56.7 GO:0032584 growth cone membrane(GO:0032584)
6.3 38.0 GO:0032280 symmetric synapse(GO:0032280)
5.6 50.0 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
4.7 23.5 GO:1990769 proximal neuron projection(GO:1990769)
3.8 11.4 GO:0033186 CAF-1 complex(GO:0033186)
3.5 10.5 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
3.4 10.2 GO:0060187 cell pole(GO:0060187)
2.6 15.5 GO:0033093 Weibel-Palade body(GO:0033093)
2.5 17.4 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
2.3 7.0 GO:0005592 collagen type XI trimer(GO:0005592)
2.0 12.2 GO:0016012 sarcoglycan complex(GO:0016012)
2.0 29.3 GO:0031045 dense core granule(GO:0031045)
1.9 5.6 GO:1990826 nucleoplasmic periphery of the nuclear pore complex(GO:1990826)
1.5 30.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
1.3 9.1 GO:0090543 Flemming body(GO:0090543)
1.1 3.4 GO:1990032 parallel fiber(GO:1990032)
1.1 6.7 GO:0005955 calcineurin complex(GO:0005955)
1.1 5.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
1.0 14.0 GO:0070852 cell body fiber(GO:0070852)
1.0 3.0 GO:0070826 paraferritin complex(GO:0070826)
1.0 2.9 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
1.0 5.8 GO:0005608 laminin-3 complex(GO:0005608)
1.0 4.8 GO:0072534 perineuronal net(GO:0072534)
0.9 6.5 GO:0071438 invadopodium membrane(GO:0071438)
0.9 7.0 GO:0044305 calyx of Held(GO:0044305)
0.8 6.9 GO:0005826 actomyosin contractile ring(GO:0005826)
0.8 75.9 GO:0042734 presynaptic membrane(GO:0042734)
0.8 13.7 GO:0043194 axon initial segment(GO:0043194)
0.7 29.2 GO:0032809 neuronal cell body membrane(GO:0032809)
0.7 3.0 GO:1990005 granular vesicle(GO:1990005)
0.7 72.4 GO:0000786 nucleosome(GO:0000786)
0.7 17.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.6 1.9 GO:0014801 longitudinal sarcoplasmic reticulum(GO:0014801)
0.6 6.7 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.6 11.7 GO:0030673 axolemma(GO:0030673)
0.6 2.9 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.6 6.4 GO:0043083 synaptic cleft(GO:0043083)
0.6 29.9 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.5 5.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.5 2.3 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.5 6.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.5 14.9 GO:0043034 costamere(GO:0043034)
0.4 2.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.4 3.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.4 5.1 GO:0030008 TRAPP complex(GO:0030008)
0.4 5.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.4 4.7 GO:0042589 zymogen granule membrane(GO:0042589)
0.4 2.3 GO:0035189 Rb-E2F complex(GO:0035189)
0.4 1.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.3 6.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.3 33.1 GO:0016605 PML body(GO:0016605)
0.3 2.0 GO:0005663 DNA replication factor C complex(GO:0005663)
0.3 8.8 GO:0048786 presynaptic active zone(GO:0048786)
0.3 14.0 GO:0032153 cell division site(GO:0032153) cell division site part(GO:0032155)
0.3 2.5 GO:0016272 prefoldin complex(GO:0016272)
0.3 6.3 GO:0043198 dendritic shaft(GO:0043198)
0.3 3.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.3 2.4 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.3 2.9 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.3 0.8 GO:0036117 hyaluranon cable(GO:0036117)
0.2 2.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2 8.4 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.2 0.7 GO:0045025 mitochondrial degradosome(GO:0045025)
0.2 1.2 GO:0097452 GAIT complex(GO:0097452)
0.2 9.2 GO:0009925 basal plasma membrane(GO:0009925)
0.2 3.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 9.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 3.9 GO:0042101 T cell receptor complex(GO:0042101)
0.2 57.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.2 8.0 GO:0002102 podosome(GO:0002102)
0.2 1.7 GO:0031209 SCAR complex(GO:0031209)
0.2 3.1 GO:0071565 nBAF complex(GO:0071565)
0.2 24.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.2 138.9 GO:0043025 neuronal cell body(GO:0043025)
0.2 3.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 2.9 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.2 2.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 8.8 GO:0030175 filopodium(GO:0030175)
0.2 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.2 6.7 GO:0034704 calcium channel complex(GO:0034704)
0.2 12.5 GO:0030427 site of polarized growth(GO:0030427)
0.2 11.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.2 14.8 GO:0016363 nuclear matrix(GO:0016363)
0.1 1.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 3.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 1.5 GO:0042555 MCM complex(GO:0042555)
0.1 7.5 GO:0032587 ruffle membrane(GO:0032587)
0.1 8.7 GO:0031225 anchored component of membrane(GO:0031225)
0.1 3.2 GO:0034451 centriolar satellite(GO:0034451)
0.1 30.3 GO:0005667 transcription factor complex(GO:0005667)
0.1 4.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 1.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 8.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 1.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 35.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 1.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.3 GO:0017119 Golgi transport complex(GO:0017119)
0.1 2.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 4.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 8.8 GO:0005814 centriole(GO:0005814)
0.1 1.6 GO:0019013 viral nucleocapsid(GO:0019013)
0.1 11.5 GO:0001650 fibrillar center(GO:0001650)
0.1 2.0 GO:0097546 ciliary base(GO:0097546)
0.1 8.0 GO:0030018 Z disc(GO:0030018)
0.1 7.8 GO:0005903 brush border(GO:0005903)
0.1 26.9 GO:0000785 chromatin(GO:0000785)
0.1 0.8 GO:0032797 SMN complex(GO:0032797)
0.1 2.8 GO:0016592 mediator complex(GO:0016592)
0.1 3.0 GO:0045171 intercellular bridge(GO:0045171)
0.1 3.3 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 5.2 GO:0000776 kinetochore(GO:0000776)
0.1 3.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 6.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 2.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.6 GO:0031519 PcG protein complex(GO:0031519)
0.0 1.1 GO:0001533 cornified envelope(GO:0001533)
0.0 8.2 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 1.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 4.6 GO:0043235 receptor complex(GO:0043235)
0.0 1.0 GO:0005581 collagen trimer(GO:0005581)
0.0 5.2 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 9.5 GO:0045202 synapse(GO:0045202)
0.0 4.1 GO:0030424 axon(GO:0030424)
0.0 1.2 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.0 2.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.5 GO:0030686 90S preribosome(GO:0030686)
0.0 9.1 GO:0005730 nucleolus(GO:0005730)
0.0 3.7 GO:0016604 nuclear body(GO:0016604)
0.0 0.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
28.8 86.4 GO:0071886 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding(GO:0071886)
12.3 49.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
10.8 43.4 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
6.3 38.0 GO:0001515 opioid peptide activity(GO:0001515)
5.2 15.7 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
4.8 14.4 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
4.5 22.3 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
3.5 10.5 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
3.2 41.7 GO:0030215 semaphorin receptor binding(GO:0030215)
2.6 13.0 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
2.5 56.4 GO:0002162 dystroglycan binding(GO:0002162)
2.2 6.6 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
2.2 15.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
2.1 10.6 GO:0005042 netrin receptor activity(GO:0005042)
1.9 9.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
1.8 7.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
1.8 10.6 GO:0003840 gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
1.7 6.7 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
1.4 7.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
1.4 11.4 GO:0070087 chromo shadow domain binding(GO:0070087)
1.4 7.0 GO:0022841 potassium ion leak channel activity(GO:0022841)
1.4 7.0 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
1.3 29.9 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
1.3 6.5 GO:0015252 hydrogen ion channel activity(GO:0015252)
1.3 20.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
1.2 6.0 GO:0004614 phosphoglucomutase activity(GO:0004614)
1.2 10.5 GO:0043495 protein anchor(GO:0043495)
1.1 10.1 GO:0015643 toxic substance binding(GO:0015643)
1.1 29.9 GO:0031402 sodium ion binding(GO:0031402)
1.0 28.1 GO:0042056 chemoattractant activity(GO:0042056)
1.0 3.0 GO:0030977 taurine binding(GO:0030977)
1.0 3.0 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) nickel cation transmembrane transporter activity(GO:0015099) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) chromium ion transmembrane transporter activity(GO:0070835)
0.8 8.3 GO:0022821 potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.8 5.7 GO:0043426 MRF binding(GO:0043426)
0.8 5.6 GO:0033592 RNA strand annealing activity(GO:0033592)
0.8 2.3 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.8 2.3 GO:0002134 UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.8 5.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.7 9.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.7 8.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.7 8.0 GO:0008046 axon guidance receptor activity(GO:0008046)
0.7 9.2 GO:0015250 water channel activity(GO:0015250)
0.6 27.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.6 7.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.6 3.6 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.6 23.4 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.6 2.9 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.6 9.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.6 3.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662) vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.5 2.7 GO:0001729 ceramide kinase activity(GO:0001729)
0.5 3.9 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.5 2.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.5 3.3 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.5 1.9 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.5 6.3 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.4 14.2 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.4 6.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.4 3.5 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.4 8.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.4 11.0 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.4 9.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.4 11.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.4 10.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.4 1.2 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.4 4.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.4 2.3 GO:0004568 chitinase activity(GO:0004568)
0.4 2.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.4 4.0 GO:0051378 serotonin binding(GO:0051378)
0.4 33.5 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.4 57.5 GO:0044325 ion channel binding(GO:0044325)
0.4 2.8 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.3 4.1 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.3 17.6 GO:0035254 glutamate receptor binding(GO:0035254)
0.3 2.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.3 0.9 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.3 7.1 GO:0003785 actin monomer binding(GO:0003785)
0.3 1.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.3 78.5 GO:0030695 GTPase regulator activity(GO:0030695)
0.3 5.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 1.2 GO:0070052 collagen V binding(GO:0070052)
0.2 3.9 GO:0005523 tropomyosin binding(GO:0005523)
0.2 1.2 GO:0005131 growth hormone receptor binding(GO:0005131)
0.2 7.0 GO:0050681 androgen receptor binding(GO:0050681)
0.2 1.7 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.2 45.3 GO:0042393 histone binding(GO:0042393)
0.2 15.5 GO:0005518 collagen binding(GO:0005518)
0.2 2.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2 7.6 GO:0005109 frizzled binding(GO:0005109)
0.2 3.1 GO:0001056 RNA polymerase III activity(GO:0001056)
0.2 1.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 2.0 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 7.2 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.2 0.8 GO:0030622 U4atac snRNA binding(GO:0030622)
0.2 4.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 2.5 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.2 1.9 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.2 1.1 GO:0008061 chitin binding(GO:0008061)
0.2 0.8 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.2 7.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 4.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 2.3 GO:0042166 acetylcholine-gated cation channel activity(GO:0022848) acetylcholine binding(GO:0042166)
0.1 0.9 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 6.7 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.1 8.1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 2.6 GO:0051861 glycolipid binding(GO:0051861)
0.1 1.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 2.1 GO:0005521 lamin binding(GO:0005521)
0.1 2.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 2.7 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.1 1.8 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.7 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.9 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 2.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.4 GO:0019863 IgE binding(GO:0019863)
0.1 9.8 GO:0030165 PDZ domain binding(GO:0030165)
0.1 11.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 2.1 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 1.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.8 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 1.7 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.9 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 3.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 3.1 GO:0004177 aminopeptidase activity(GO:0004177)
0.1 2.4 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 17.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 16.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 27.7 GO:0046982 protein heterodimerization activity(GO:0046982)
0.1 18.2 GO:0003712 transcription cofactor activity(GO:0003712)
0.1 12.2 GO:0016758 transferase activity, transferring hexosyl groups(GO:0016758)
0.1 3.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 1.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 3.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 15.4 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 7.6 GO:0004386 helicase activity(GO:0004386)
0.1 1.0 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1 7.1 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.1 2.2 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 4.4 GO:0008565 protein transporter activity(GO:0008565)
0.0 4.7 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 1.2 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 7.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.6 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 1.6 GO:0004532 exoribonuclease activity(GO:0004532)
0.0 0.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.8 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 23.0 GO:0008270 zinc ion binding(GO:0008270)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 75.0 NABA COLLAGENS Genes encoding collagen proteins
1.0 49.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.8 32.0 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.7 14.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.6 38.9 PID LKB1 PATHWAY LKB1 signaling events
0.6 6.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.6 20.4 PID RAS PATHWAY Regulation of Ras family activation
0.5 6.6 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.5 10.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.4 11.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.4 9.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.4 29.2 PID AP1 PATHWAY AP-1 transcription factor network
0.4 2.6 PID IL5 PATHWAY IL5-mediated signaling events
0.4 5.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.4 7.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.3 5.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 8.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.3 17.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.3 11.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.3 10.5 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.3 8.9 ST G ALPHA I PATHWAY G alpha i Pathway
0.3 9.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.3 2.4 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.3 14.1 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.3 3.0 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.3 11.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 6.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2 1.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 15.1 PID E2F PATHWAY E2F transcription factor network
0.2 1.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 9.1 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.2 6.4 PID RHOA PATHWAY RhoA signaling pathway
0.2 11.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.2 2.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 2.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.2 3.0 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.2 9.8 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.2 4.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.2 1.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 4.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 3.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 5.7 PID PLK1 PATHWAY PLK1 signaling events
0.1 1.9 PID AURORA A PATHWAY Aurora A signaling
0.1 1.6 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 5.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 4.1 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 1.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 2.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 2.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 2.0 PID ATR PATHWAY ATR signaling pathway
0.1 1.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 0.8 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 1.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 7.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.4 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
6.2 86.4 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
2.7 76.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
1.9 42.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
1.8 11.0 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
1.7 10.5 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
1.3 75.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
1.1 15.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
1.1 18.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.9 17.6 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.9 24.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.9 14.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.8 14.1 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.8 10.6 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.8 9.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.6 16.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.6 10.8 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.5 7.0 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.5 10.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.5 9.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.5 13.0 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.5 12.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.5 5.9 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.4 23.7 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.4 6.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.4 5.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.4 7.1 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.4 4.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.4 9.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.4 6.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.3 4.8 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.3 5.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.3 3.0 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.3 46.7 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.3 6.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.3 3.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.2 7.0 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.2 7.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.2 3.9 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.2 5.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2 2.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 6.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 7.5 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.2 8.1 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.2 2.7 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.2 6.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.2 2.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2 14.9 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.2 2.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.2 3.1 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.2 2.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 1.3 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 2.9 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 2.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 2.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 0.7 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 1.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 4.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 4.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 4.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 3.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 0.9 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.1 2.5 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 4.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 4.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 5.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 0.9 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.1 5.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 2.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 0.9 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 2.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.8 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 2.3 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.8 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 1.1 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 1.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation