Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation
Downloads

Results for Gbx1_Nobox_Alx3

Z-value: 0.50

Motif logo

Transcription factors associated with Gbx1_Nobox_Alx3

Gene Symbol Gene ID Gene Info
ENSRNOG00000013369 gastrulation brain homeobox 1
ENSRNOG00000025720 NOBOX oogenesis homeobox
ENSRNOG00000018290 ALX homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Noboxrn6_v1_chr4_-_72756887_727568870.106.6e-02Click!
Gbx1rn6_v1_chr4_+_7173961_7173961-0.053.3e-01Click!
Alx3rn6_v1_chr2_+_210381829_210381829-0.053.6e-01Click!

Activity profile of Gbx1_Nobox_Alx3 motif

Sorted Z-values of Gbx1_Nobox_Alx3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_7058314 17.44 ENSRNOT00000045996
3-hydroxyanthranilate 3,4-dioxygenase
chr1_+_279633671 16.18 ENSRNOT00000036012
ENSRNOT00000091669
coiled-coil domain containing 172
chr2_+_54466280 15.82 ENSRNOT00000033112
complement C6
chr4_-_157304653 14.02 ENSRNOT00000051613
leucine rich repeat containing 23
chr13_-_76049363 13.90 ENSRNOT00000075865
ENSRNOT00000007455
BMP/retinoic acid inducible neural specific 2
chr16_+_10267482 13.84 ENSRNOT00000085255
growth differentiation factor 2
chr9_+_20241062 13.21 ENSRNOT00000071593
leucine-rich repeat-containing protein 23-like
chr2_-_219262901 12.40 ENSRNOT00000037068
G-protein coupled receptor 88
chr8_+_106449321 11.86 ENSRNOT00000018622
retinol binding protein 1
chr6_+_2216623 10.89 ENSRNOT00000008045
regulator of microtubule dynamics 2
chr10_-_93675991 9.40 ENSRNOT00000090662
membrane associated ring-CH-type finger 10
chr9_-_81566096 9.39 ENSRNOT00000019497
angio-associated, migratory cell protein
chr2_-_60657712 9.18 ENSRNOT00000040348
retinoic acid induced 14
chr4_-_17594598 9.12 ENSRNOT00000008936
semaphorin 3E
chr10_-_87248572 8.83 ENSRNOT00000066637
ENSRNOT00000085677
keratin 26
chr4_+_22898527 8.45 ENSRNOT00000072455
ENSRNOT00000076123
DBF4 zinc finger
chr9_+_53013413 7.81 ENSRNOT00000005313
ankyrin and armadillo repeat containing
chr16_+_2634603 7.76 ENSRNOT00000019113
HESX homeobox 1
chr5_+_61474000 7.16 ENSRNOT00000013930
coiled-coil domain containing 180
chr14_+_76732650 7.09 ENSRNOT00000088197
cytokine-dependent hematopoietic cell linker
chr10_-_87232723 6.84 ENSRNOT00000015150
keratin 25
chr2_-_250862419 6.76 ENSRNOT00000017943
chloride channel accessory 4
chr5_+_117698764 6.75 ENSRNOT00000011486
angiopoietin-like 3
chr4_+_6827429 6.49 ENSRNOT00000071737
Ras homolog enriched in brain
chr20_+_44680449 6.23 ENSRNOT00000000728
Traf3 interacting protein 2
chr3_-_165700489 6.04 ENSRNOT00000017008
zinc finger protein 93
chr18_-_16543992 5.96 ENSRNOT00000036306
solute carrier family 39 member 6
chr19_+_25043680 5.91 ENSRNOT00000043971
adhesion G protein-coupled receptor L1
chr7_-_68549763 5.90 ENSRNOT00000078014
solute carrier family 16 member 7
chrX_+_84064427 5.85 ENSRNOT00000046364
zinc finger protein 711
chr7_-_68512397 5.51 ENSRNOT00000058036
solute carrier family 16 member 7
chr4_+_147832136 5.49 ENSRNOT00000064603
rhodopsin
chr1_+_140998240 5.44 ENSRNOT00000023506
ENSRNOT00000090897
abhydrolase domain containing 2
chr11_-_71284939 5.26 ENSRNOT00000002421

chr2_-_138833933 5.04 ENSRNOT00000013343
protocadherin 18
chr5_-_115387377 5.01 ENSRNOT00000036030
ENSRNOT00000077492
similar to hypothetical protein MGC34837
chr3_-_57607683 4.98 ENSRNOT00000093222
ENSRNOT00000058524
methyltransferase like 8
chr8_+_85503224 4.91 ENSRNOT00000012348
glutathione S-transferase alpha 4
chr14_+_59611434 4.86 ENSRNOT00000065366
cholecystokinin A receptor
chr9_-_81566642 4.84 ENSRNOT00000080345
angio-associated, migratory cell protein
chr7_-_143228060 4.78 ENSRNOT00000088923
ENSRNOT00000012640
keratin 75
chr8_-_53816447 4.77 ENSRNOT00000011454
tetratricopeptide repeat domain 12
chr4_-_100252755 4.76 ENSRNOT00000017301
vesicle-associated membrane protein 8
chr14_-_16903242 4.72 ENSRNOT00000003001
shroom family member 3
chr2_+_80269661 4.66 ENSRNOT00000015975

chr16_+_50049828 4.64 ENSRNOT00000034448
family with sequence similarity 149, member A
chr5_+_50381244 4.59 ENSRNOT00000012385
glycoprotein hormones, alpha polypeptide
chr8_+_47674321 4.57 ENSRNOT00000026170
ENSRNOT00000078776
tripartite motif-containing 29
chr17_+_72160735 4.56 ENSRNOT00000038817
inter-alpha-trypsin inhibitor heavy chain 2
chr5_-_78985990 4.51 ENSRNOT00000009248
alpha-1-microglobulin/bikunin precursor
chr2_+_72006099 4.51 ENSRNOT00000034044
cadherin 12
chr11_-_14304603 4.42 ENSRNOT00000040202
ENSRNOT00000082143
SAM domain, SH3 domain and nuclear localization signals, 1
chr10_-_87468711 4.33 ENSRNOT00000039983
keratin associated protein 3-3
chr1_-_43638161 4.32 ENSRNOT00000024460
interaction protein for cytohesin exchange factors 1
chr18_+_81694808 4.24 ENSRNOT00000020446
cytochrome b5 type A
chr3_-_90751055 4.24 ENSRNOT00000040741
LRRGT00091
chr4_-_88684415 4.23 ENSRNOT00000009001
similar to 40S ribosomal protein S7 (S8)
chr1_+_185210922 4.21 ENSRNOT00000055120
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
chr20_-_30947484 4.17 ENSRNOT00000065614
phosphatase domain containing, paladin 1
chr11_+_45751812 4.06 ENSRNOT00000079336
similar to Dermal papilla derived protein 7
chr6_-_78549669 4.05 ENSRNOT00000009940
forkhead box A1
chr1_-_89539210 4.04 ENSRNOT00000077462
ENSRNOT00000028644
hepsin
chr3_-_66417741 4.01 ENSRNOT00000007662
neuronal differentiation 1
chr6_-_108660063 3.98 ENSRNOT00000006240
apoptosis resistant E3 ubiquitin protein ligase 1
chr8_+_57983556 3.98 ENSRNOT00000009562
similar to RIKEN cDNA 4930550C14
chr4_-_80395502 3.97 ENSRNOT00000014437
neuropeptide VF precursor
chr11_+_61609370 3.83 ENSRNOT00000088880
ENSRNOT00000082533
GRAM domain containing 1C
chr4_-_21920651 3.79 ENSRNOT00000066211
transmembrane protein 243
chr10_-_87529599 3.75 ENSRNOT00000074099
keratin associated protein 2-1
chr14_-_19072677 3.63 ENSRNOT00000060548
similar to alpha-fetoprotein
chr2_+_252090669 3.58 ENSRNOT00000020656
lysophosphatidic acid receptor 3
chr7_+_60316290 3.57 ENSRNOT00000085673
lysozyme C type 2
chr8_+_41350182 3.56 ENSRNOT00000072823
olfactory receptor 143-like
chr6_-_115616766 3.43 ENSRNOT00000006143
ENSRNOT00000045870
SEL1L ERAD E3 ligase adaptor subunit
chr9_-_4876023 3.36 ENSRNOT00000065839
similar to Sulfotransferase K1 (rSULT1C2)
chr6_-_114476723 3.35 ENSRNOT00000005162
deiodinase, iodothyronine, type II
chr10_-_87286387 3.31 ENSRNOT00000044206
keratin 28
chr7_-_145062956 3.23 ENSRNOT00000055274
similar to CDNA sequence BC048502
chr10_+_62981297 3.23 ENSRNOT00000031618
EF-hand calcium binding domain 5
chr14_-_21252538 3.17 ENSRNOT00000005003
ameloblastin
chr16_-_73152921 3.16 ENSRNOT00000048602
zinc finger, matrin type 4
chr3_-_103745236 3.12 ENSRNOT00000006876
NUT midline carcinoma, family member 1
chr10_+_82032656 3.12 ENSRNOT00000067751
ankyrin repeat domain 40
chr7_+_60316045 3.08 ENSRNOT00000064594
lysozyme C type 2
chr7_-_143497108 3.06 ENSRNOT00000048613
keratin 76
chr13_+_79378733 3.00 ENSRNOT00000039221
tumor necrosis factor superfamily member 18
chr8_-_114617466 2.96 ENSRNOT00000082992
ENSRNOT00000038160
collagen type VI alpha 5 chain
chr6_-_77421286 2.95 ENSRNOT00000011453
NK2 homeobox 1
chr17_+_25082056 2.90 ENSRNOT00000037041

chr1_-_227932603 2.88 ENSRNOT00000033795
membrane spanning 4-domains A6A
chr6_+_132510757 2.87 ENSRNOT00000080230
Enah/Vasp-like
chr12_-_45801842 2.87 ENSRNOT00000078837

chrX_+_105011489 2.87 ENSRNOT00000085068
ADP ribosylation factor like GTPase 13A
chr10_-_88670430 2.78 ENSRNOT00000025547
hypocretin neuropeptide precursor
chr13_-_90405591 2.77 ENSRNOT00000006849
VANGL planar cell polarity protein 2
chr17_+_47301511 2.75 ENSRNOT00000092051
ENSRNOT00000087178
NME/NM23 family member 8
chr12_+_18679789 2.69 ENSRNOT00000001863
cytochrome P450, family 3, subfamily a, polypeptide 9
chr10_+_87782376 2.68 ENSRNOT00000017415
hypothetical protein LOC680396
chr17_+_47302272 2.67 ENSRNOT00000090021
NME/NM23 family member 8
chr14_+_96499520 2.65 ENSRNOT00000074692

chr8_-_12993651 2.64 ENSRNOT00000033932
lysine demethylase 4D
chr3_+_113319456 2.60 ENSRNOT00000051354
creatine kinase, mitochondrial 1
chr6_-_36876805 2.58 ENSRNOT00000006482
mesogenin 1
chr20_-_10013190 2.58 ENSRNOT00000084726
ENSRNOT00000089112
radial spoke head 1 homolog
chr13_+_82438697 2.51 ENSRNOT00000003759
selectin P
chr11_-_46693565 2.50 ENSRNOT00000044900
interphotoreceptor matrix proteoglycan 2
chr19_-_58735173 2.48 ENSRNOT00000030077
pecanex homolog 2 (Drosophila)
chr13_+_91054974 2.47 ENSRNOT00000091089
C-reactive protein
chr9_+_81566074 2.40 ENSRNOT00000074131
ENSRNOT00000046229
ENSRNOT00000090383
paroxysmal nonkinesigenic dyskinesia
chr1_+_225037737 2.33 ENSRNOT00000077959
BSCL2, seipin lipid droplet biogenesis associated
chr10_+_91217079 2.29 ENSRNOT00000004218
hexamethylene bis-acetamide inducible 2
chr13_-_95250235 2.23 ENSRNOT00000085648
AKT serine/threonine kinase 3
chrX_+_118197217 2.23 ENSRNOT00000090922
5-hydroxytryptamine receptor 2C
chr19_-_25961666 2.21 ENSRNOT00000004091
calreticulin
chr8_-_40137390 2.13 ENSRNOT00000042717
pannexin 3
chr16_-_25192675 2.13 ENSRNOT00000032289
membrane associated ring-CH-type finger 1
chrX_+_74200972 2.09 ENSRNOT00000076956
cysteine-rich hydrophobic domain 1
chr1_+_87066289 2.07 ENSRNOT00000027645
calpain 12
chr5_-_12526962 2.04 ENSRNOT00000092104
suppression of tumorigenicity 18
chr14_-_104612597 2.04 ENSRNOT00000007002
solute carrier family 1 member 4
chr1_-_199159125 2.03 ENSRNOT00000025618
BCL tumor suppressor 7C
chr14_+_91588940 2.03 ENSRNOT00000057067
hypothetical LOC289778
chrX_-_16532089 2.00 ENSRNOT00000093156
diacylglycerol kinase kappa
chr3_+_15560712 1.99 ENSRNOT00000010218
prostaglandin-endoperoxide synthase 1
chr7_-_73130740 1.98 ENSRNOT00000075584
RIKEN cDNA 9430069I07 gene
chr2_-_122641409 1.96 ENSRNOT00000068334
defective in cullin neddylation 1 domain containing 1
chr3_+_19174027 1.95 ENSRNOT00000074445

chrX_+_74205842 1.89 ENSRNOT00000077003
cysteine-rich hydrophobic domain 1
chr10_+_70242874 1.85 ENSRNOT00000010924
fibronectin type III domain containing 8
chr5_+_133819726 1.81 ENSRNOT00000081075
Scl/Tal1 interrupting locus
chr1_-_166912524 1.81 ENSRNOT00000092952
inositol polyphosphate phosphatase-like 1
chr3_-_76696107 1.77 ENSRNOT00000044692
olfactory receptor 629
chr3_-_45169118 1.75 ENSRNOT00000086371
coiled-coil domain containing 148
chr5_+_117583502 1.73 ENSRNOT00000010933
ubiquitin specific peptidase 1
chrX_+_14578264 1.72 ENSRNOT00000038994
cytochrome b-245 beta chain
chr1_-_24604400 1.72 ENSRNOT00000081175
RIKEN cDNA 1700020N01 gene
chrX_+_148421627 1.68 ENSRNOT00000016754
cancer/testis antigen 2
chrX_-_124464963 1.67 ENSRNOT00000036472
ENSRNOT00000077697
transmembrane protein 255A
chr1_+_278557792 1.66 ENSRNOT00000023414
attractin like 1
chr7_+_44009069 1.64 ENSRNOT00000005523
MGAT4 family, member C
chrY_-_1398030 1.62 ENSRNOT00000088719
ubiquitin specific peptidase 9, Y-linked
chr7_-_28711761 1.61 ENSRNOT00000006249
PARP1 binding protein
chr6_-_128149220 1.59 ENSRNOT00000014204
goosecoid homeobox
chr20_+_3558827 1.59 ENSRNOT00000088130
discoidin domain receptor tyrosine kinase 1
chr3_+_16846412 1.54 ENSRNOT00000074266

chr17_-_45746753 1.53 ENSRNOT00000077475
similar to brain Zn-finger protein
chr5_+_133620706 1.53 ENSRNOT00000053202
predicted gene 12830
chr2_+_154604832 1.51 ENSRNOT00000013777
vomeronasal 2 receptor 44
chr11_-_782954 1.50 ENSRNOT00000040065
Eph receptor A3
chr4_+_2055615 1.49 ENSRNOT00000007646
ring finger protein 32
chr4_+_148476943 1.48 ENSRNOT00000017689
olfactory receptor 823
chr3_+_19045214 1.48 ENSRNOT00000070878

chr4_-_30380119 1.47 ENSRNOT00000036460
paraoxonase 2
chr12_-_17186679 1.47 ENSRNOT00000001730
UNC homeobox
chr3_+_94530586 1.46 ENSRNOT00000067860
cleavage stimulation factor subunit 3
chr4_-_50312608 1.45 ENSRNOT00000010019
Fez family zinc finger 1
chr4_+_117962319 1.43 ENSRNOT00000057441
transforming growth factor alpha
chr1_-_89269930 1.43 ENSRNOT00000028532
free fatty acid receptor 2
chr5_-_28130803 1.42 ENSRNOT00000093186
solute carrier family 26 member 7
chr3_+_149643481 1.42 ENSRNOT00000020713
BPI fold containing family A, member 5
chr1_-_101095594 1.38 ENSRNOT00000027944
Fc fragment of IgG receptor and transporter
chr13_+_56546021 1.38 ENSRNOT00000016797
abnormal spindle microtubule assembly
chr6_+_8886591 1.36 ENSRNOT00000091510
ENSRNOT00000089174
SIX homeobox 3
chr12_+_22727335 1.36 ENSRNOT00000077293
zinc finger, HIT-type containing 1
chr10_-_86004096 1.35 ENSRNOT00000091978
ENSRNOT00000066855
SH3 and cysteine rich domain 2
chr11_+_31539016 1.30 ENSRNOT00000072856
interferon alpha and beta receptor subunit 2
chr2_-_35104963 1.28 ENSRNOT00000018058
regulator of G-protein signaling 7-binding protein
chr6_-_111417813 1.27 ENSRNOT00000016324
ENSRNOT00000085458
serine palmitoyltransferase, long chain base subunit 2
chr4_-_148845267 1.24 ENSRNOT00000037397
transmembrane protein 72
chr12_-_44911147 1.22 ENSRNOT00000071074
ENSRNOT00000046190
kinase suppressor of ras 2
chr5_-_93244202 1.21 ENSRNOT00000075474
protein tyrosine phosphatase, receptor type, D
chr7_-_143167772 1.21 ENSRNOT00000011374
keratin 85
chr8_+_40410604 1.21 ENSRNOT00000049392
olfactory receptor 1202
chr1_-_173764246 1.18 ENSRNOT00000019690
ENSRNOT00000086944
LIM domain only 1
chr9_+_4107246 1.18 ENSRNOT00000078212

chr13_+_49005405 1.17 ENSRNOT00000092560
ENSRNOT00000076457
LEM domain containing 1
chr19_-_44095250 1.15 ENSRNOT00000074824
transmembrane protein 170A
chr11_-_54567357 1.14 ENSRNOT00000046890
resistin like beta
chr3_+_55461420 1.13 ENSRNOT00000073549
glucose-6-phosphatase catalytic subunit 2
chrY_-_1305026 1.13 ENSRNOT00000092901
ubiquitin specific peptidase 9, Y-linked
chr5_-_28131133 1.13 ENSRNOT00000067331
solute carrier family 26 member 7
chr5_+_135574172 1.13 ENSRNOT00000023416
testis-specific kinase 2
chr12_-_22726982 1.12 ENSRNOT00000001921
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr14_-_21128505 1.12 ENSRNOT00000004776
RUN and FYVE domain containing 3
chrX_-_35777243 1.12 ENSRNOT00000040912
retinoschisin 1
chr5_-_12172009 1.09 ENSRNOT00000061903
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chrX_-_18341467 1.07 ENSRNOT00000045802
spindlin family, member 2A
chr6_-_72805848 1.05 ENSRNOT00000009040
G protein-coupled receptor 33
chr9_+_117795132 1.04 ENSRNOT00000086943
A-kinase anchor inhibitor 1
chr1_+_169966190 1.00 ENSRNOT00000023307
olfactory receptor 190
chr16_-_14348046 1.00 ENSRNOT00000018630
cadherin-related family member 1
chr10_+_56601288 1.00 ENSRNOT00000023724
GABA type A receptor-associated protein
chr7_+_41475163 0.99 ENSRNOT00000037844
dual specificity phosphatase 6
chr7_+_58570579 0.97 ENSRNOT00000081227
RIKEN cDNA A930009A15 gene
chr3_-_122947075 0.97 ENSRNOT00000082369
PC-esterase domain containing 1A
chr15_+_44441856 0.92 ENSRNOT00000018006
gonadotropin releasing hormone 1
chr1_-_167971151 0.89 ENSRNOT00000043023
olfactory receptor 53
chr10_-_13446135 0.89 ENSRNOT00000084991
potassium channel tetramerization domain containing 5
chr3_-_10196626 0.88 ENSRNOT00000012234
PR/SET domain 12
chr12_-_22138382 0.88 ENSRNOT00000001899
leucine rich repeats and calponin homology domain containing 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Gbx1_Nobox_Alx3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 15.8 GO:0001969 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
4.4 17.4 GO:0019805 quinolinate biosynthetic process(GO:0019805)
2.5 12.4 GO:0061743 motor learning(GO:0061743)
2.3 11.4 GO:1901475 pyruvate transmembrane transport(GO:1901475)
1.6 4.8 GO:1903595 pancreatic amylase secretion(GO:0036395) regulation of pancreatic amylase secretion(GO:1902276) positive regulation of histamine secretion by mast cell(GO:1903595)
1.5 11.9 GO:0006776 vitamin A metabolic process(GO:0006776)
1.4 4.2 GO:0071579 regulation of zinc ion transport(GO:0071579)
1.4 6.8 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
1.3 4.0 GO:0034769 basement membrane disassembly(GO:0034769)
1.2 4.9 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
1.2 8.3 GO:0030916 otic vesicle formation(GO:0030916)
1.0 4.0 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
1.0 10.0 GO:0018298 protein-chromophore linkage(GO:0018298)
1.0 3.0 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.9 2.8 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.9 2.6 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.8 3.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.8 6.5 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.8 4.1 GO:0060741 prostate gland stromal morphogenesis(GO:0060741) alveolar secondary septum development(GO:0061144)
0.7 2.2 GO:0031583 phospholipase D-activating G-protein coupled receptor signaling pathway(GO:0031583)
0.7 2.2 GO:0002397 MHC class I protein complex assembly(GO:0002397)
0.7 13.8 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.7 2.7 GO:0009822 lipid hydroxylation(GO:0002933) alkaloid catabolic process(GO:0009822)
0.6 6.0 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.6 1.7 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.5 2.0 GO:0015811 L-cystine transport(GO:0015811)
0.5 1.5 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.5 7.9 GO:0006590 thyroid hormone generation(GO:0006590)
0.5 5.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.5 2.9 GO:0021759 globus pallidus development(GO:0021759)
0.5 2.4 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.4 1.3 GO:0006667 sphinganine metabolic process(GO:0006667)
0.4 2.5 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.4 2.0 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.4 1.1 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.4 1.1 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.4 1.4 GO:0002877 leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752) regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877)
0.4 8.4 GO:0035584 calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.3 2.8 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.3 6.2 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.3 1.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.3 0.9 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.3 4.9 GO:0009635 response to herbicide(GO:0009635)
0.3 3.4 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.3 0.8 GO:0060166 olfactory pit development(GO:0060166) Harderian gland development(GO:0070384)
0.3 6.8 GO:0045109 intermediate filament organization(GO:0045109)
0.3 9.1 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.2 3.6 GO:0032060 bleb assembly(GO:0032060)
0.2 2.1 GO:0034214 protein hexamerization(GO:0034214)
0.2 1.4 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
0.2 6.6 GO:0019835 cytolysis(GO:0019835)
0.2 0.7 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.2 5.0 GO:0048240 sperm capacitation(GO:0048240)
0.2 2.3 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.2 3.1 GO:0048733 sebaceous gland development(GO:0048733)
0.2 1.8 GO:0033504 floor plate development(GO:0033504)
0.2 1.0 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.2 0.6 GO:0007356 thorax and anterior abdomen determination(GO:0007356) vestibulocochlear nerve formation(GO:0021650)
0.2 2.6 GO:1902358 oxalate transport(GO:0019532) sulfate transmembrane transport(GO:1902358)
0.2 13.9 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.2 1.5 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.2 14.2 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.2 1.8 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.2 1.6 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.2 4.6 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.2 2.3 GO:0034389 lipid particle organization(GO:0034389)
0.2 0.9 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.2 0.5 GO:0070212 protein poly-ADP-ribosylation(GO:0070212) regulation of telomeric DNA binding(GO:1904742)
0.2 0.6 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.2 0.5 GO:1902211 regulation of prolactin signaling pathway(GO:1902211)
0.1 1.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 1.7 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 0.8 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 1.4 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 1.6 GO:0014029 neural crest formation(GO:0014029)
0.1 0.5 GO:0072592 positive regulation of integrin biosynthetic process(GO:0045726) pH elevation(GO:0045852) intracellular pH elevation(GO:0051454) oxygen metabolic process(GO:0072592)
0.1 3.4 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 2.0 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 1.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 4.4 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.1 2.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 2.0 GO:0045116 protein neddylation(GO:0045116)
0.1 0.6 GO:0014717 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.1 0.5 GO:0050955 thermoception(GO:0050955)
0.1 0.6 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 1.0 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.5 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 0.7 GO:0000459 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.1 1.4 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.1 0.6 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.1 1.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 2.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 7.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 0.5 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.1 0.3 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.9 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.6 GO:0015866 ADP transport(GO:0015866)
0.1 1.1 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 0.9 GO:0046599 regulation of centriole replication(GO:0046599)
0.1 0.9 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 0.7 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 0.8 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.1 1.3 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 5.5 GO:0006334 nucleosome assembly(GO:0006334)
0.1 0.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.8 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 2.6 GO:0035082 axoneme assembly(GO:0035082)
0.0 2.6 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 2.3 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 0.4 GO:0099612 protein localization to axon(GO:0099612)
0.0 3.2 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.3 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 2.5 GO:0032091 negative regulation of protein binding(GO:0032091)
0.0 4.0 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.4 GO:0098880 maintenance of postsynaptic specialization structure(GO:0098880) maintenance of postsynaptic density structure(GO:0099562)
0.0 0.3 GO:0046549 retinal cone cell development(GO:0046549)
0.0 3.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.7 GO:0032288 myelin assembly(GO:0032288)
0.0 1.2 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 3.7 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.1 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.1 GO:0090648 response to environmental enrichment(GO:0090648)
0.0 1.2 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.1 GO:0097264 self proteolysis(GO:0097264)
0.0 1.9 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.2 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.7 GO:0018149 peptide cross-linking(GO:0018149)
0.0 3.1 GO:0045444 fat cell differentiation(GO:0045444)
0.0 0.1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.6 GO:0060997 dendritic spine morphogenesis(GO:0060997)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 15.8 GO:0005579 membrane attack complex(GO:0005579)
1.6 4.8 GO:0035577 azurophil granule membrane(GO:0035577)
1.1 3.4 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.9 2.8 GO:0060187 cell pole(GO:0060187)
0.9 5.4 GO:0036157 outer dynein arm(GO:0036157) sperm cytoplasmic droplet(GO:0097598)
0.8 2.5 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.8 5.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.6 2.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.6 2.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.5 14.2 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.4 6.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.3 6.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.3 4.0 GO:0072687 meiotic spindle(GO:0072687)
0.3 19.6 GO:0045095 keratin filament(GO:0045095)
0.2 0.9 GO:1990005 granular vesicle(GO:1990005)
0.2 2.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 15.9 GO:0005882 intermediate filament(GO:0005882)
0.2 4.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 1.3 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.9 GO:0097441 basilar dendrite(GO:0097441)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 1.4 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.8 GO:0031209 SCAR complex(GO:0031209)
0.1 2.9 GO:0005921 gap junction(GO:0005921)
0.1 11.7 GO:0072562 blood microparticle(GO:0072562)
0.1 0.7 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 2.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.4 GO:1990769 proximal neuron projection(GO:1990769)
0.1 0.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.1 GO:0071437 invadopodium(GO:0071437)
0.1 8.2 GO:0000922 spindle pole(GO:0000922)
0.0 1.0 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.1 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 2.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 4.1 GO:0005902 microvillus(GO:0005902)
0.0 4.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.9 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.5 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0071547 piP-body(GO:0071547)
0.0 0.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 6.1 GO:0005681 spliceosomal complex(GO:0005681)
0.0 3.8 GO:0043296 apical junction complex(GO:0043296)
0.0 2.7 GO:0043195 terminal bouton(GO:0043195)
0.0 1.4 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 10.3 GO:0044297 cell body(GO:0044297)
0.0 0.4 GO:0001533 cornified envelope(GO:0001533)
0.0 1.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 7.8 GO:0005813 centrosome(GO:0005813)
0.0 0.7 GO:0016235 aggresome(GO:0016235)
0.0 2.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 3.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.9 GO:0043204 perikaryon(GO:0043204)
0.0 1.4 GO:0001650 fibrillar center(GO:0001650)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 11.4 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
1.1 17.4 GO:0016918 retinal binding(GO:0016918)
0.9 4.5 GO:0019862 IgA binding(GO:0019862)
0.8 3.2 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.8 6.8 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.7 9.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.7 2.0 GO:0071886 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding(GO:0071886)
0.6 17.4 GO:0019825 oxygen binding(GO:0019825)
0.6 2.5 GO:0042806 fucose binding(GO:0042806)
0.5 2.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.5 4.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.5 6.6 GO:0003796 lysozyme activity(GO:0003796)
0.5 2.0 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.5 1.5 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.5 2.4 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.4 1.3 GO:0019961 interferon binding(GO:0019961)
0.4 5.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.4 4.8 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.4 1.1 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.4 2.6 GO:0004111 creatine kinase activity(GO:0004111)
0.3 2.4 GO:0001849 complement component C1q binding(GO:0001849)
0.3 6.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.3 4.0 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.3 5.9 GO:0015643 toxic substance binding(GO:0015643)
0.3 2.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.3 1.4 GO:0019770 IgG receptor activity(GO:0019770)
0.3 1.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.3 4.9 GO:0043295 glutathione binding(GO:0043295)
0.3 5.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.3 1.3 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 2.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.2 13.8 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.2 2.9 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.2 4.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.2 1.6 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2 1.1 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.2 1.8 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.2 17.2 GO:0051082 unfolded protein binding(GO:0051082)
0.2 1.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 2.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.2 2.8 GO:0097602 cullin family protein binding(GO:0097602)
0.2 2.9 GO:0005522 profilin binding(GO:0005522)
0.2 1.5 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.9 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 4.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 2.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 2.9 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.8 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.6 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.6 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 1.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 4.6 GO:0070888 E-box binding(GO:0070888)
0.1 6.3 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 2.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.7 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 1.0 GO:0004875 complement receptor activity(GO:0004875)
0.1 1.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 13.3 GO:0003774 motor activity(GO:0003774)
0.1 4.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 3.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 2.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 1.3 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.6 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 2.0 GO:0004601 peroxidase activity(GO:0004601)
0.1 3.0 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 1.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.8 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 8.7 GO:0016874 ligase activity(GO:0016874)
0.0 6.3 GO:0005179 hormone activity(GO:0005179)
0.0 4.2 GO:0020037 heme binding(GO:0020037)
0.0 4.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.4 GO:0042287 MHC protein binding(GO:0042287)
0.0 1.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.9 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.0 2.2 GO:0005080 protein kinase C binding(GO:0005080)
0.0 3.7 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 4.8 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.0 2.3 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 1.9 GO:0019003 GDP binding(GO:0019003)
0.0 0.7 GO:0019843 rRNA binding(GO:0019843)
0.0 1.1 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.4 GO:0098919 structural constituent of postsynaptic specialization(GO:0098879) structural constituent of postsynaptic density(GO:0098919)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 17.2 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 1.5 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 8.1 GO:0003682 chromatin binding(GO:0003682)
0.0 0.7 GO:0008186 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 13.8 PID ALK1 PATHWAY ALK1 signaling events
0.3 6.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.3 11.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.2 5.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.2 1.8 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 11.0 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.1 7.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 6.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 1.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 3.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 3.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 2.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 3.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 2.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 0.9 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 1.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 2.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 9.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.6 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 7.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 17.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.8 11.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.7 6.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.7 5.5 REACTOME OPSINS Genes involved in Opsins
0.5 18.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.5 9.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.5 5.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.4 4.9 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.3 6.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.3 2.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 2.2 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.2 7.7 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.2 4.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.2 1.7 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.2 3.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.2 4.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 4.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.0 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 2.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 4.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 2.0 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 1.8 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 2.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.7 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.6 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.6 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 2.5 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 2.0 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 6.7 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.1 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 2.6 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease