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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Gata3

Z-value: 2.17

Motif logo

Transcription factors associated with Gata3

Gene Symbol Gene ID Gene Info
ENSRNOG00000019336 GATA binding protein 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gata3rn6_v1_chr17_+_72429618_72429618-0.302.7e-08Click!

Activity profile of Gata3 motif

Sorted Z-values of Gata3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_72889270 38.16 ENSRNOT00000058843
ENSRNOT00000034957
troponin T1, slow skeletal type
chrX_-_64715823 37.38 ENSRNOT00000076297
ankyrin repeat and SOCS box-containing 12
chr14_-_86047162 35.33 ENSRNOT00000018227
phosphoglycerate mutase 2
chr4_-_132111079 33.86 ENSRNOT00000013719
eukaryotic translation initiation factor 4E family member 3
chr9_-_73948583 33.52 ENSRNOT00000018097
myosin, light chain 1
chrX_+_71342775 33.35 ENSRNOT00000004888
integrin subunit beta 1 binding protein 2
chr10_+_45289741 33.34 ENSRNOT00000066190
histone cluster 3, H2ba
chr2_+_104416972 33.16 ENSRNOT00000017125
tripartite motif-containing 55
chr1_+_193537137 33.09 ENSRNOT00000029967

chr16_+_25773602 32.08 ENSRNOT00000047750
glyceraldehyde-3-phosphate dehydrogenase, pseudogene 2
chr1_-_197858016 31.04 ENSRNOT00000074778
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr5_+_115649046 30.95 ENSRNOT00000041328
glyceraldehyde-3-phosphate dehydrogenase
chr10_-_8498422 30.30 ENSRNOT00000082332
RNA binding protein, fox-1 homolog 1
chr8_+_45561390 30.09 ENSRNOT00000047820

chr4_-_129619142 28.10 ENSRNOT00000047453
leiomodin 3
chr6_+_113898420 28.10 ENSRNOT00000064872
neurexin 3
chr10_-_45297385 27.95 ENSRNOT00000041187
histone cluster 3 H2B family member b
chr10_-_109729019 27.92 ENSRNOT00000054959
protein phosphatase 1, regulatory subunit 27
chr17_-_18592750 27.72 ENSRNOT00000065742
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr8_-_80631873 27.68 ENSRNOT00000091661
ENSRNOT00000080662
unc-13 homolog C
chr11_+_60073383 26.99 ENSRNOT00000087508
transgelin 3
chr12_+_46257343 26.50 ENSRNOT00000083569
transmembrane protein 233
chr3_-_52510507 26.50 ENSRNOT00000091259
sodium voltage-gated channel alpha subunit 1
chr10_-_90999506 26.09 ENSRNOT00000034401
glial fibrillary acidic protein
chr3_-_63568464 25.81 ENSRNOT00000068494

chr4_-_89151184 24.71 ENSRNOT00000010263
nucleosome assembly protein 1-like 5
chr6_+_23337571 24.71 ENSRNOT00000011832
similar to hypothetical protein MGC38716
chr6_-_26624092 24.63 ENSRNOT00000008113
tripartite motif-containing 54
chr5_-_155258392 23.57 ENSRNOT00000017065
complement C1q C chain
chr10_+_53778662 23.33 ENSRNOT00000045718
myosin heavy chain 2
chr14_-_112946204 23.25 ENSRNOT00000056813
coiled-coil domain-containing protein 85A-like
chr14_+_108826831 22.90 ENSRNOT00000083146
ENSRNOT00000009421
B-cell CLL/lymphoma 11A
chr6_+_112203679 22.71 ENSRNOT00000031205
neurexin 3
chr18_+_83777665 22.28 ENSRNOT00000018682
cerebellin 2 precursor
chr7_-_119896925 22.09 ENSRNOT00000010609
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr3_+_16413080 21.79 ENSRNOT00000040386
Ig kappa chain V19-17-like
chr18_-_63825408 21.45 ENSRNOT00000043709
similar to glyceraldehyde-3-phosphate dehydrogenase
chr9_+_37727942 21.24 ENSRNOT00000016511
ENSRNOT00000074276
myotilin-like
chr2_+_252771017 21.21 ENSRNOT00000075452
ENSRNOT00000055318
tubulin tyrosine ligase like 7
chr4_+_106323089 21.20 ENSRNOT00000091402

chr4_+_102147211 21.04 ENSRNOT00000083239

chrX_+_70563570 21.04 ENSRNOT00000003772
glycerophosphodiester phosphodiesterase domain containing 2
chr17_-_61332391 20.94 ENSRNOT00000034599
SNRPN upstream reading frame protein-like
chr13_+_103396314 20.50 ENSRNOT00000049499
solute carrier family 30, member 10
chr3_+_113251778 20.37 ENSRNOT00000083005
microtubule-associated protein 1A
chr15_-_33656089 20.35 ENSRNOT00000024186
myosin heavy chain 7
chr3_-_94182714 19.55 ENSRNOT00000015073
hypothetical protein LOC100362814
chr13_+_47602692 19.51 ENSRNOT00000038822
Fc fragment of IgM receptor
chr1_+_165482155 19.13 ENSRNOT00000024005
uncoupling protein 3
chr10_-_102289837 19.10 ENSRNOT00000044922

chr10_-_27179900 19.04 ENSRNOT00000082445
gamma-aminobutyric acid type A receptor gamma 2 subunit
chr6_+_48708368 18.97 ENSRNOT00000005905
myelin transcription factor 1-like
chr18_-_28438654 18.66 ENSRNOT00000036301
marginal zone B and B1 cell-specific protein
chr18_-_18079560 18.65 ENSRNOT00000072093

chr4_-_85915099 18.63 ENSRNOT00000016182
neuronal differentiation 6
chr10_-_90995982 18.62 ENSRNOT00000093266
glial fibrillary acidic protein
chr3_-_158328881 18.40 ENSRNOT00000044466
protein tyrosine phosphatase, receptor type, T
chr14_+_60764409 18.17 ENSRNOT00000005168
leucine-rich repeat LGI family, member 2
chr3_+_20303979 18.12 ENSRNOT00000058331

chrX_-_32355296 18.08 ENSRNOT00000081652
ENSRNOT00000065075
adaptor-related protein complex 1, sigma 2 subunit
chr11_+_85430400 18.07 ENSRNOT00000083198

chr1_-_101360971 17.95 ENSRNOT00000028164
lin-7 homolog B, crumbs cell polarity complex component
chr17_+_12762752 17.69 ENSRNOT00000044842
DIRAS family GTPase 2
chr3_-_129357348 17.61 ENSRNOT00000084829
ENSRNOT00000007410
p21 (RAC1) activated kinase 7
chr5_+_140888973 17.50 ENSRNOT00000020524
5'-nucleotidase, cytosolic IA
chr1_-_167202767 17.46 ENSRNOT00000055243
ADP-ribosyltransferase 5
chrX_-_15707436 17.38 ENSRNOT00000085907
synaptophysin
chr2_-_210943620 17.36 ENSRNOT00000026750
G protein-coupled receptor 61
chr10_+_19366793 17.35 ENSRNOT00000050610
family with sequence similarity 196, member B
chr15_+_51756978 17.10 ENSRNOT00000024067
early growth response 3
chr6_+_76349362 17.05 ENSRNOT00000043224
aldolase 1 A retrogene 2
chr13_+_52625441 17.03 ENSRNOT00000012095
troponin I1, slow skeletal type
chr3_+_57770948 16.95 ENSRNOT00000038429

chr13_+_52624878 16.61 ENSRNOT00000076054
ENSRNOT00000076299
troponin I1, slow skeletal type
chr7_-_136853957 16.59 ENSRNOT00000008985
neural EGFL like 2
chr8_+_100260049 16.47 ENSRNOT00000011090

chr10_+_83636518 16.45 ENSRNOT00000007352
phosphoethanolamine/phosphocholine phosphatase 1
chr17_+_88215834 16.41 ENSRNOT00000034098
G protein-coupled receptor 158
chr17_-_31706523 16.30 ENSRNOT00000071312

chr2_+_222792999 16.25 ENSRNOT00000036228

chr1_-_89358166 16.15 ENSRNOT00000044532
myelin-associated glycoprotein
chr3_+_132052612 15.91 ENSRNOT00000030148

chrX_-_64800435 15.90 ENSRNOT00000005663
ankyrin repeat and SOCS box-containing 12
chr15_-_70399924 15.79 ENSRNOT00000087940
diaphanous-related formin 3
chr5_+_154800226 15.72 ENSRNOT00000016046
5-hydroxytryptamine receptor 1D
chr2_+_36246628 15.66 ENSRNOT00000013618
5-hydroxytryptamine receptor 1A
chr17_+_15924048 15.65 ENSRNOT00000050696
WNK lysine deficient protein kinase 2
chr18_-_60835739 15.61 ENSRNOT00000039569
similar to glyceraldehyde-3-phosphate dehydrogenase
chr4_-_103646906 15.45 ENSRNOT00000047620

chr3_+_155103150 15.30 ENSRNOT00000020720
solute carrier family 32 member 1
chr13_-_82005741 15.25 ENSRNOT00000076404
methyltransferase like 11B
chr13_+_99663150 15.24 ENSRNOT00000036705
cornichon family AMPA receptor auxiliary protein 3
chr20_-_15334745 15.21 ENSRNOT00000067633
protocadherin 15
chr7_-_143353925 15.16 ENSRNOT00000068533
keratin 71
chr4_-_103369224 15.15 ENSRNOT00000075709

chr15_-_14737704 15.10 ENSRNOT00000011307
synaptoporin
chr3_-_16753987 15.08 ENSRNOT00000091257

chr3_+_16495748 15.08 ENSRNOT00000045492

chr6_-_128989812 14.99 ENSRNOT00000085943
ankyrin repeat and SOCS box protein 2-like
chr3_+_11593655 14.86 ENSRNOT00000074122
phosphatidylinositol-4-phosphate 5-kinase-like 1
chr1_-_5165859 14.85 ENSRNOT00000044325
ENSRNOT00000019319
glutamate metabotropic receptor 1
chr1_-_227441442 14.85 ENSRNOT00000028433
membrane spanning 4-domains A1
chr3_-_11885311 14.81 ENSRNOT00000021189
ENSRNOT00000021178
syntaxin binding protein 1
chr5_-_130085838 14.77 ENSRNOT00000035252
ELAV like RNA binding protein 4
chr5_+_22380334 14.76 ENSRNOT00000009744
clavesin 1
chr3_+_16753703 14.65 ENSRNOT00000077741

chr4_+_102489916 14.57 ENSRNOT00000082031

chr10_+_65586504 14.56 ENSRNOT00000015535
ENSRNOT00000046388
aldolase, fructose-bisphosphate C
chr17_+_44760056 14.46 ENSRNOT00000052073
similar to H3 histone, family 3B
chr5_+_162031722 14.42 ENSRNOT00000020483
leucine rich repeat containing 38
chr6_-_138900915 14.41 ENSRNOT00000075363

chr10_-_110585376 14.34 ENSRNOT00000054917
Rab40b, member RAS oncogene family
chr6_-_141062581 14.29 ENSRNOT00000073446

chr13_-_82006005 14.27 ENSRNOT00000039581
methyltransferase like 11B
chr14_+_75880410 14.27 ENSRNOT00000014078
heparan sulfate-glucosamine 3-sulfotransferase 1
chr5_-_147827863 14.24 ENSRNOT00000075659
coiled coil domain containing 28B
chr9_+_81816872 14.12 ENSRNOT00000041407
phospholipase C, delta 4
chr13_-_51183269 14.09 ENSRNOT00000039540
PTPRF interacting protein alpha 4
chr13_-_103080920 14.08 ENSRNOT00000034990

chr4_-_103258134 14.07 ENSRNOT00000086827

chr3_-_17081510 13.99 ENSRNOT00000063862

chr1_+_25173242 13.77 ENSRNOT00000016518
clavesin 2
chr5_-_58950373 13.75 ENSRNOT00000060442
Cd72 molecule
chr5_+_22392732 13.72 ENSRNOT00000087182
clavesin 1
chr3_-_72219246 13.62 ENSRNOT00000009903
smoothelin-like 1
chr6_-_138632159 13.56 ENSRNOT00000082921
ENSRNOT00000040702
immunoglobulin heavy constant mu
chr7_-_44121130 13.53 ENSRNOT00000005706
neurotensin
chr3_-_16999720 13.39 ENSRNOT00000074382
similar to immunoglobulin kappa-chain VK-1
chr2_-_144323254 13.25 ENSRNOT00000018780
serine-rich and transmembrane domain containing 1
chr1_-_198128857 13.23 ENSRNOT00000026496
coronin 1A
chr3_+_19274273 13.09 ENSRNOT00000040102

chr9_+_73528681 12.97 ENSRNOT00000084340
unc-80 homolog, NALCN activator
chr3_+_17139670 12.95 ENSRNOT00000073316

chr2_-_140618405 12.86 ENSRNOT00000017736
SET domain containing (lysine methyltransferase) 7
chr20_-_28263037 12.74 ENSRNOT00000030348
ectodysplasin-A receptor
chr4_-_103115522 12.72 ENSRNOT00000074206

chr18_+_59748444 12.72 ENSRNOT00000024752
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr4_+_102068556 12.72 ENSRNOT00000077412

chr3_+_51737904 12.69 ENSRNOT00000007069
sodium voltage-gated channel alpha subunit 2
chr3_-_16537433 12.57 ENSRNOT00000048523

chr6_-_140880070 12.55 ENSRNOT00000073779
uncharacterized LOC691828
chr13_-_90602365 12.43 ENSRNOT00000009344
calsequestrin 1
chr11_+_86092468 12.36 ENSRNOT00000057971
lambda-chain C1-region-like
chr1_+_192233910 12.29 ENSRNOT00000016418
ENSRNOT00000016442
protein kinase C, beta
chr1_+_272799784 12.13 ENSRNOT00000016052
insulin 1
chr17_-_31916553 12.12 ENSRNOT00000074220
uncharacterized LOC100911032
chr6_-_138631997 12.08 ENSRNOT00000073304

chr4_+_102262007 12.05 ENSRNOT00000079328

chr12_+_48316143 12.00 ENSRNOT00000084511
SV2 related protein
chr3_-_51643140 11.98 ENSRNOT00000006646
sodium voltage-gated channel alpha subunit 3
chr20_+_3830376 11.95 ENSRNOT00000085547
collagen type XI alpha 2 chain
chr2_+_226825635 11.89 ENSRNOT00000042173

chr6_-_141147264 11.84 ENSRNOT00000042900
Igh protein-like
chr17_-_31813716 11.84 ENSRNOT00000074147

chr2_+_189629297 11.83 ENSRNOT00000049810
DENN domain containing 4B
chr3_+_18706988 11.82 ENSRNOT00000074650

chr3_-_105512939 11.67 ENSRNOT00000011773
actin, alpha, cardiac muscle 1
chr10_-_108691367 11.65 ENSRNOT00000005067
neuronal pentraxin 1
chr3_+_2591331 11.62 ENSRNOT00000017466
suppressor APC domain containing 2
chr4_-_168656673 11.54 ENSRNOT00000009341
G protein-coupled receptor 19
chr17_+_44763598 11.50 ENSRNOT00000079880
histone cluster 1, H3b
chr1_-_98521706 11.38 ENSRNOT00000015941
sialic acid binding Ig-like lectin 10
chr16_+_39827749 11.31 ENSRNOT00000074885
WD repeat domain 17
chr10_-_31493419 11.27 ENSRNOT00000009211
IL2-inducible T-cell kinase
chr12_-_22211071 11.23 ENSRNOT00000087817
ENSRNOT00000001910
actin-like 6B
chr3_+_19441604 11.16 ENSRNOT00000090581

chr5_-_77173502 11.15 ENSRNOT00000023588
solute carrier family 46, member 2
chr4_+_70828894 11.10 ENSRNOT00000064892
T cell receptor beta, constant 2
chr6_+_147876557 11.09 ENSRNOT00000080090
transmembrane protein 196
chr6_-_142676432 11.06 ENSRNOT00000074947

chr8_+_130401470 11.06 ENSRNOT00000043346
zinc finger and BTB domain containing 47
chr9_+_41295909 11.01 ENSRNOT00000018935
Rho guanine nucleotide exchange factor 4
chr2_+_40554146 10.99 ENSRNOT00000015138
phosphodiesterase 4D
chr5_+_18963937 10.97 ENSRNOT00000082188

chr11_+_70687500 10.81 ENSRNOT00000037432

chr14_+_46649971 10.80 ENSRNOT00000085875

chr5_+_142875773 10.77 ENSRNOT00000082120
ENSRNOT00000056496
EPH receptor A10
chr10_-_56962161 10.76 ENSRNOT00000026038
arachidonate 15-lipoxygenase
chr15_-_61564695 10.68 ENSRNOT00000068216
regulator of cell cycle
chr20_+_3875706 10.66 ENSRNOT00000036900
RT1 class II, locus Ha
chr4_+_101909389 10.57 ENSRNOT00000086458

chr4_+_102643934 10.54 ENSRNOT00000058389
uncharacterized LOC100911032
chr1_-_100980340 10.52 ENSRNOT00000064272
protein arginine methyltransferase 1
chr1_-_215836641 10.51 ENSRNOT00000080246
insulin-like growth factor 2
chr2_+_113984824 10.50 ENSRNOT00000086399
TRAF2 and NCK interacting kinase
chr1_-_98521551 10.48 ENSRNOT00000081922
sialic acid binding Ig-like lectin 10
chr2_+_113984646 10.42 ENSRNOT00000016799
TRAF2 and NCK interacting kinase
chr16_+_16949232 10.42 ENSRNOT00000047499

chr1_-_219422268 10.42 ENSRNOT00000025092
carnosine synthase 1
chr2_+_83393282 10.36 ENSRNOT00000044871
catenin delta 2
chr1_+_219250265 10.33 ENSRNOT00000024353
double C2-like domains, gamma
chr9_-_13877130 10.27 ENSRNOT00000015705
leucine rich repeat and fibronectin type III domain containing 2
chr3_-_60611924 10.18 ENSRNOT00000068745
chimerin 1
chrX_+_65800059 10.16 ENSRNOT00000076428
G protein-coupled receptor 165
chr13_-_89594738 10.04 ENSRNOT00000004641
translocase of outer mitochondrial membrane 40 like
chr15_+_344685 9.98 ENSRNOT00000065542
ENSRNOT00000066928
potassium calcium-activated channel subfamily M alpha 1
chr18_+_14471213 9.97 ENSRNOT00000045224
dystrobrevin, alpha
chr4_+_98481520 9.97 ENSRNOT00000078381
ENSRNOT00000048493

chr6_+_139405966 9.90 ENSRNOT00000088974

chr17_-_54808483 9.83 ENSRNOT00000075683

Network of associatons between targets according to the STRING database.

First level regulatory network of Gata3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
19.5 58.5 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
10.3 31.0 GO:0031448 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) positive regulation of endoplasmic reticulum calcium ion concentration(GO:0032470)
10.3 30.9 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
9.8 29.5 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
7.6 22.9 GO:1903860 negative regulation of dendrite extension(GO:1903860)
7.5 44.7 GO:1904714 positive regulation of Schwann cell proliferation(GO:0010625) regulation of chaperone-mediated autophagy(GO:1904714)
6.0 18.1 GO:0071579 regulation of zinc ion transport(GO:0071579)
5.8 17.4 GO:2000474 regulation of opioid receptor signaling pathway(GO:2000474)
5.0 35.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
4.9 14.8 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
4.7 18.7 GO:2001274 immunoglobulin biosynthetic process(GO:0002378) negative regulation of glucose import in response to insulin stimulus(GO:2001274)
4.4 13.2 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
4.2 12.7 GO:1990743 protein sialylation(GO:1990743)
4.1 12.3 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
3.7 11.0 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
3.6 10.7 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
3.5 28.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
3.3 10.0 GO:0060082 eye blink reflex(GO:0060082)
3.3 26.2 GO:0014883 transition between fast and slow fiber(GO:0014883)
3.1 12.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
3.1 24.7 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
3.0 17.9 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
3.0 8.9 GO:0046103 inosine biosynthetic process(GO:0046103)
2.8 50.8 GO:0090129 positive regulation of synapse maturation(GO:0090129)
2.7 10.9 GO:0002188 translation reinitiation(GO:0002188)
2.7 13.5 GO:0097332 response to antipsychotic drug(GO:0097332)
2.6 10.5 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
2.6 15.7 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
2.6 10.4 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
2.6 7.8 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
2.6 12.8 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
2.6 7.7 GO:1990091 sodium-dependent self proteolysis(GO:1990091)
2.5 15.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
2.5 14.9 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
2.5 7.4 GO:0031632 positive regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031632)
2.4 26.8 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
2.4 7.2 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
2.3 9.4 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
2.3 18.7 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
2.3 9.3 GO:0050893 sensory processing(GO:0050893)
2.3 9.2 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
2.3 6.9 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
2.3 9.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
2.2 9.0 GO:1901423 response to benzene(GO:1901423)
2.2 8.9 GO:1902473 regulation of protein localization to synapse(GO:1902473) positive regulation of protein localization to synapse(GO:1902474)
2.2 10.8 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
2.1 15.0 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
2.1 6.4 GO:0018343 protein farnesylation(GO:0018343)
2.1 16.9 GO:0007021 tubulin complex assembly(GO:0007021)
2.0 6.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
2.0 6.1 GO:0021589 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) lateral motor column neuron migration(GO:0097477)
2.0 11.9 GO:0060023 soft palate development(GO:0060023)
1.9 11.6 GO:2000354 regulation of ovarian follicle development(GO:2000354)
1.9 5.8 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
1.9 5.7 GO:1990009 retinal cell apoptotic process(GO:1990009)
1.9 3.8 GO:0033123 positive regulation of purine nucleotide catabolic process(GO:0033123)
1.8 24.0 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
1.8 36.6 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
1.8 12.7 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
1.8 7.3 GO:1904975 response to bleomycin(GO:1904975)
1.8 23.3 GO:0001778 plasma membrane repair(GO:0001778)
1.8 5.4 GO:0000189 MAPK import into nucleus(GO:0000189) diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
1.8 5.4 GO:0019417 sulfur oxidation(GO:0019417)
1.8 17.5 GO:0046085 adenosine metabolic process(GO:0046085)
1.7 12.2 GO:0046684 response to pyrethroid(GO:0046684)
1.7 22.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.7 5.2 GO:0033566 gamma-tubulin complex localization(GO:0033566)
1.7 8.6 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
1.7 6.8 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
1.7 11.8 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
1.7 15.2 GO:0050957 equilibrioception(GO:0050957)
1.7 6.7 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
1.7 8.3 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
1.6 4.8 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
1.6 22.3 GO:0071420 cellular response to histamine(GO:0071420)
1.6 22.2 GO:0007256 activation of JNKK activity(GO:0007256)
1.6 12.7 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
1.5 6.0 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
1.5 6.0 GO:0035470 positive regulation of vascular wound healing(GO:0035470) hematopoietic stem cell migration(GO:0035701) response to ultrasound(GO:1990478)
1.5 16.5 GO:0090527 actin filament reorganization(GO:0090527)
1.5 10.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
1.5 16.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
1.5 4.4 GO:1905076 peptidyl-serine ADP-ribosylation(GO:0018312) myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760) regulation of interleukin-17 secretion(GO:1905076) negative regulation of interleukin-17 secretion(GO:1905077) negative regulation of ATP biosynthetic process(GO:2001170)
1.4 8.5 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
1.4 7.1 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
1.4 4.2 GO:0060300 regulation of cytokine activity(GO:0060300)
1.4 7.0 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
1.4 2.8 GO:0042940 D-amino acid transport(GO:0042940)
1.4 5.6 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
1.4 16.6 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
1.4 4.1 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
1.3 5.3 GO:0090204 protein localization to nuclear pore(GO:0090204)
1.3 52.0 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
1.3 12.9 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
1.3 6.4 GO:0006741 NADP biosynthetic process(GO:0006741)
1.3 3.8 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
1.3 11.3 GO:0001865 NK T cell differentiation(GO:0001865)
1.2 4.9 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
1.2 17.1 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
1.2 23.0 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
1.2 14.3 GO:0035865 cellular response to potassium ion(GO:0035865)
1.2 11.9 GO:0070837 dehydroascorbic acid transport(GO:0070837)
1.2 127.6 GO:0006334 nucleosome assembly(GO:0006334)
1.2 8.2 GO:0061718 NADH regeneration(GO:0006735) positive regulation of glucokinase activity(GO:0033133) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) positive regulation of hexokinase activity(GO:1903301)
1.2 7.0 GO:1990928 response to amino acid starvation(GO:1990928)
1.2 12.7 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
1.1 7.8 GO:0000492 box C/D snoRNP assembly(GO:0000492)
1.0 24.1 GO:0045109 intermediate filament organization(GO:0045109)
1.0 6.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
1.0 10.3 GO:0018095 protein polyglutamylation(GO:0018095)
1.0 5.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
1.0 3.0 GO:0097296 regulation of lung blood pressure(GO:0014916) positive regulation of transforming growth factor beta3 production(GO:0032916) activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
1.0 2.0 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
1.0 5.9 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
1.0 18.6 GO:0021542 dentate gyrus development(GO:0021542)
1.0 9.7 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
1.0 8.6 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.9 2.8 GO:0045751 regulation of Toll signaling pathway(GO:0008592) negative regulation of Toll signaling pathway(GO:0045751)
0.9 2.8 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.9 12.7 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.9 2.7 GO:0046952 ketone body catabolic process(GO:0046952)
0.9 3.5 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.9 6.0 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.9 1.7 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
0.9 3.4 GO:0032701 negative regulation of interleukin-18 production(GO:0032701)
0.8 3.4 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.8 5.9 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.8 3.3 GO:0045794 negative regulation of cell volume(GO:0045794)
0.8 5.8 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.8 5.7 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317) response to water-immersion restraint stress(GO:1990785)
0.8 4.9 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.8 3.2 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.8 8.1 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.8 3.2 GO:2000416 regulation of eosinophil migration(GO:2000416) positive regulation of eosinophil migration(GO:2000418)
0.8 3.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.8 2.4 GO:0002477 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481)
0.8 1.6 GO:1905065 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.8 7.0 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.8 13.1 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.8 1.5 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.8 4.6 GO:0032825 positive regulation of natural killer cell differentiation(GO:0032825)
0.8 3.8 GO:0019372 lipoxygenase pathway(GO:0019372)
0.8 6.9 GO:0032230 positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.8 7.6 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.8 9.8 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.8 3.0 GO:0048143 negative regulation of photoreceptor cell differentiation(GO:0046533) astrocyte activation(GO:0048143) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.7 4.5 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.7 2.2 GO:1900368 regulation of RNA interference(GO:1900368)
0.7 3.7 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.7 8.1 GO:0099612 protein localization to axon(GO:0099612)
0.7 2.9 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.7 14.3 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.7 2.8 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.7 33.3 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.7 60.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.7 4.9 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.7 7.0 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.7 0.7 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.7 7.7 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.7 6.3 GO:0051026 chiasma assembly(GO:0051026)
0.7 3.5 GO:1904401 cellular response to Thyroid stimulating hormone(GO:1904401)
0.7 2.1 GO:1903544 response to butyrate(GO:1903544)
0.7 11.0 GO:0031643 positive regulation of myelination(GO:0031643)
0.7 8.1 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.7 3.3 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.7 4.0 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.7 6.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.6 3.8 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.6 10.0 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.6 3.7 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.6 3.1 GO:0010701 positive regulation of chronic inflammatory response(GO:0002678) positive regulation of norepinephrine secretion(GO:0010701)
0.6 4.9 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
0.6 7.3 GO:0035630 bone mineralization involved in bone maturation(GO:0035630)
0.6 2.4 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.6 7.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.6 1.8 GO:0010903 negative regulation of cytokine secretion involved in immune response(GO:0002740) negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) diacylglycerol catabolic process(GO:0046340)
0.6 10.7 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.6 3.0 GO:0030222 eosinophil differentiation(GO:0030222)
0.6 4.7 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007) negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.6 2.2 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.5 3.2 GO:0072675 osteoclast fusion(GO:0072675)
0.5 1.1 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.5 5.8 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.5 1.0 GO:2000078 positive regulation of type B pancreatic cell development(GO:2000078)
0.5 9.2 GO:0035641 locomotory exploration behavior(GO:0035641)
0.5 3.0 GO:0032790 ribosome disassembly(GO:0032790)
0.5 4.0 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.5 4.0 GO:0019388 galactose catabolic process(GO:0019388)
0.5 2.5 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.5 3.5 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.5 3.9 GO:0002934 desmosome organization(GO:0002934)
0.5 2.4 GO:0043418 homocysteine catabolic process(GO:0043418)
0.5 4.9 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.5 8.1 GO:0034453 microtubule anchoring(GO:0034453)
0.5 6.2 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.5 6.2 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.5 5.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206) negative regulation of axon regeneration(GO:0048681)
0.5 1.4 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.5 4.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.5 16.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.5 27.2 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.4 7.2 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.4 10.7 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.4 6.7 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.4 3.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.4 5.3 GO:0032096 negative regulation of response to food(GO:0032096)
0.4 5.3 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.4 6.1 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.4 4.3 GO:0090161 Golgi ribbon formation(GO:0090161)
0.4 2.6 GO:0061635 regulation of protein complex stability(GO:0061635)
0.4 3.4 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.4 4.2 GO:0032098 regulation of appetite(GO:0032098)
0.4 2.5 GO:0044351 macropinocytosis(GO:0044351)
0.4 12.0 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.4 5.6 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.4 1.2 GO:0051697 protein delipidation(GO:0051697)
0.4 0.8 GO:1903817 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.4 2.7 GO:1904117 cellular response to vasopressin(GO:1904117)
0.4 3.1 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.4 0.8 GO:0051660 establishment of centrosome localization(GO:0051660)
0.4 1.9 GO:0090367 negative regulation of mRNA modification(GO:0090367)
0.4 9.6 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.4 0.8 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.4 1.9 GO:0035627 ceramide transport(GO:0035627)
0.4 2.3 GO:0035898 parathyroid hormone secretion(GO:0035898)
0.4 20.6 GO:0045761 regulation of adenylate cyclase activity(GO:0045761)
0.4 2.2 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.4 5.1 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.4 1.5 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.4 1.5 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.4 5.0 GO:0015671 oxygen transport(GO:0015671)
0.4 9.3 GO:0035066 positive regulation of histone acetylation(GO:0035066) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.4 7.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.4 13.0 GO:0042220 response to cocaine(GO:0042220)
0.4 3.5 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205)
0.4 2.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.3 3.1 GO:0015684 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.3 5.2 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.3 0.3 GO:1904170 regulation of bleb assembly(GO:1904170)
0.3 6.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.3 7.9 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.3 22.5 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.3 5.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.3 28.8 GO:0014823 response to activity(GO:0014823)
0.3 3.7 GO:0021559 trigeminal nerve development(GO:0021559)
0.3 6.3 GO:0097503 sialylation(GO:0097503)
0.3 31.6 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.3 6.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.3 14.7 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.3 1.9 GO:0043249 erythrocyte maturation(GO:0043249)
0.3 12.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.3 11.0 GO:0046847 filopodium assembly(GO:0046847)
0.3 7.2 GO:0045116 protein neddylation(GO:0045116)
0.3 1.9 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.3 4.3 GO:0000042 protein targeting to Golgi(GO:0000042)
0.3 4.0 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.3 6.3 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.3 10.4 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.3 9.9 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.3 26.5 GO:0060048 cardiac muscle contraction(GO:0060048)
0.3 3.4 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.3 1.7 GO:0045625 regulation of T-helper 1 cell differentiation(GO:0045625)
0.3 2.5 GO:0042711 maternal behavior(GO:0042711)
0.3 352.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.3 6.3 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.3 17.7 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.3 3.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.3 2.1 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.3 1.9 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.3 6.6 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.3 2.1 GO:0097327 response to antineoplastic agent(GO:0097327)
0.3 1.0 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.3 7.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.3 1.3 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.2 2.7 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.2 4.4 GO:1905144 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.2 2.9 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.2 7.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 9.9 GO:0006096 glycolytic process(GO:0006096)
0.2 3.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 2.5 GO:0072431 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400)
0.2 3.0 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.2 3.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.2 1.9 GO:0060967 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by RNA(GO:0060967)
0.2 20.8 GO:0006413 translational initiation(GO:0006413)
0.2 1.6 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.2 1.8 GO:1904251 regulation of bile acid metabolic process(GO:1904251)
0.2 1.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.2 6.4 GO:0000186 activation of MAPKK activity(GO:0000186)
0.2 2.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 1.9 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.2 1.7 GO:0033504 floor plate development(GO:0033504)
0.2 1.6 GO:0042501 regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141) serine phosphorylation of STAT protein(GO:0042501)
0.2 4.9 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.2 15.8 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.2 3.3 GO:0007602 phototransduction(GO:0007602)
0.2 2.7 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.2 0.3 GO:0032621 interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661) positive regulation of interleukin-18 production(GO:0032741)
0.2 0.9 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.2 0.8 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.2 2.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.9 GO:0001842 neural fold formation(GO:0001842)
0.1 3.5 GO:0045214 sarcomere organization(GO:0045214)
0.1 2.8 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.1 3.0 GO:0045616 regulation of keratinocyte differentiation(GO:0045616)
0.1 8.6 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.1 3.6 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 2.8 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 1.5 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 2.0 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 2.6 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.1 9.9 GO:0006338 chromatin remodeling(GO:0006338)
0.1 8.3 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway(GO:2001237)
0.1 2.5 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.1 4.7 GO:0007091 metaphase/anaphase transition of mitotic cell cycle(GO:0007091) regulation of mitotic sister chromatid separation(GO:0010965) metaphase/anaphase transition of cell cycle(GO:0044784)
0.1 0.6 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.1 3.5 GO:0097421 liver regeneration(GO:0097421)
0.1 1.1 GO:0044819 mitotic G1 DNA damage checkpoint(GO:0031571) mitotic G1/S transition checkpoint(GO:0044819)
0.1 2.8 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 1.8 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 1.3 GO:2000678 negative regulation of transcription regulatory region DNA binding(GO:2000678)
0.1 1.0 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 1.1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1 0.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 3.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.1 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589)
0.1 8.2 GO:0006457 protein folding(GO:0006457)
0.1 0.3 GO:1904781 regulation of protein localization to centrosome(GO:1904779) positive regulation of protein localization to centrosome(GO:1904781)
0.1 2.2 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 1.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 0.8 GO:0031167 rRNA methylation(GO:0031167)
0.1 1.3 GO:0021696 cerebellar cortex morphogenesis(GO:0021696)
0.0 0.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095) G2 DNA damage checkpoint(GO:0031572)
0.0 0.7 GO:0019236 response to pheromone(GO:0019236)
0.0 1.1 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 0.6 GO:0045738 negative regulation of DNA repair(GO:0045738) negative regulation of double-strand break repair(GO:2000780)
0.0 0.6 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.2 GO:0060290 transdifferentiation(GO:0060290)
0.0 1.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.0 GO:2000373 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.0 0.3 GO:0051132 NK T cell activation(GO:0051132)
0.0 1.3 GO:0072384 organelle transport along microtubule(GO:0072384)
0.0 1.8 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 0.3 GO:0007413 axonal fasciculation(GO:0007413)
0.0 3.5 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.8 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 1.6 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 1.5 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.2 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 1.2 GO:0045576 mast cell activation(GO:0045576)
0.0 2.4 GO:0006364 rRNA processing(GO:0006364)
0.0 1.2 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 2.3 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.3 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.6 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.3 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 0.1 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 1.0 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.9 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.8 GO:0042633 molting cycle(GO:0042303) hair cycle(GO:0042633)
0.0 0.8 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.2 GO:0036065 fucosylation(GO:0036065)
0.0 1.3 GO:0006261 DNA-dependent DNA replication(GO:0006261)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
11.2 44.7 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
6.0 71.8 GO:0005861 troponin complex(GO:0005861)
5.4 16.2 GO:1990015 mesaxon(GO:0097453) ensheathing process(GO:1990015)
4.1 33.2 GO:0097452 GAIT complex(GO:0097452)
4.0 11.9 GO:0005592 collagen type XI trimer(GO:0005592)
3.7 14.9 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
3.1 12.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
3.1 15.3 GO:0044316 cone cell pedicle(GO:0044316)
2.7 53.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
2.6 23.3 GO:0005826 actomyosin contractile ring(GO:0005826)
2.6 7.8 GO:0005896 interleukin-6 receptor complex(GO:0005896)
2.5 24.8 GO:0048787 presynaptic active zone membrane(GO:0048787)
2.2 8.7 GO:0030121 AP-1 adaptor complex(GO:0030121)
2.1 16.5 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
2.0 16.3 GO:0044305 calyx of Held(GO:0044305)
2.0 45.9 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
2.0 15.7 GO:0043203 axon hillock(GO:0043203)
1.9 28.7 GO:0034709 methylosome(GO:0034709)
1.9 83.9 GO:0031672 A band(GO:0031672)
1.8 18.2 GO:0042788 polysomal ribosome(GO:0042788)
1.7 5.2 GO:0008275 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) gamma-tubulin small complex(GO:0008275)
1.7 18.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
1.7 20.3 GO:0005859 muscle myosin complex(GO:0005859)
1.6 9.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
1.5 9.2 GO:0097441 basilar dendrite(GO:0097441)
1.5 7.4 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
1.4 8.5 GO:0044308 axonal spine(GO:0044308)
1.4 4.1 GO:0005594 collagen type IX trimer(GO:0005594)
1.3 28.1 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
1.3 2.6 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
1.2 8.5 GO:0000137 Golgi cis cisterna(GO:0000137)
1.2 116.3 GO:0000786 nucleosome(GO:0000786)
1.1 1.1 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
1.1 10.0 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
1.1 6.6 GO:1990246 uniplex complex(GO:1990246)
1.0 5.2 GO:0030314 junctional membrane complex(GO:0030314)
1.0 4.1 GO:0097149 centralspindlin complex(GO:0097149)
1.0 3.0 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
1.0 4.9 GO:0070552 BRISC complex(GO:0070552)
1.0 8.6 GO:0071821 FANCM-MHF complex(GO:0071821)
0.9 3.8 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
0.9 8.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.9 3.5 GO:0005927 muscle tendon junction(GO:0005927)
0.8 6.8 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.8 2.5 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.8 4.8 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.8 11.2 GO:0016514 SWI/SNF complex(GO:0016514)
0.8 6.1 GO:0016272 prefoldin complex(GO:0016272)
0.7 7.4 GO:0031143 pseudopodium(GO:0031143)
0.7 97.9 GO:0031674 I band(GO:0031674)
0.7 7.3 GO:0042101 T cell receptor complex(GO:0042101)
0.7 54.9 GO:0030016 myofibril(GO:0030016)
0.7 61.9 GO:0001750 photoreceptor outer segment(GO:0001750)
0.7 9.2 GO:0032426 stereocilium tip(GO:0032426)
0.7 8.5 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.7 2.1 GO:0032398 MHC class Ib protein complex(GO:0032398)
0.7 2.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.7 19.7 GO:0048786 presynaptic active zone(GO:0048786)
0.7 4.7 GO:0070761 pre-snoRNP complex(GO:0070761)
0.7 10.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.7 20.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.6 3.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.6 4.5 GO:0071986 Ragulator complex(GO:0071986)
0.6 7.3 GO:0005796 Golgi lumen(GO:0005796)
0.6 3.0 GO:0097361 CIA complex(GO:0097361)
0.6 4.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.6 9.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.6 9.3 GO:0044292 dendrite terminus(GO:0044292)
0.5 5.5 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.5 8.1 GO:0043194 axon initial segment(GO:0043194)
0.5 2.7 GO:0097165 nuclear stress granule(GO:0097165)
0.5 4.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.5 2.0 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.5 2.4 GO:0071797 LUBAC complex(GO:0071797)
0.5 5.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.5 24.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.5 6.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.5 4.1 GO:0005688 U6 snRNP(GO:0005688)
0.5 5.0 GO:0005833 hemoglobin complex(GO:0005833)
0.4 1.7 GO:0033643 host cell part(GO:0033643)
0.4 2.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.4 2.1 GO:1990696 stereocilia ankle link complex(GO:0002142) USH2 complex(GO:1990696)
0.4 34.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.4 29.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.4 1.1 GO:1990812 growth cone filopodium(GO:1990812)
0.4 3.7 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.4 5.8 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.4 26.1 GO:0045095 keratin filament(GO:0045095)
0.4 3.5 GO:0031091 platelet alpha granule(GO:0031091)
0.3 2.7 GO:0033290 eukaryotic 43S preinitiation complex(GO:0016282) eukaryotic 48S preinitiation complex(GO:0033290)
0.3 12.6 GO:0042734 presynaptic membrane(GO:0042734)
0.3 1.3 GO:0035363 histone locus body(GO:0035363)
0.3 7.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.3 8.9 GO:0030863 cortical cytoskeleton(GO:0030863)
0.3 7.2 GO:0031594 neuromuscular junction(GO:0031594)
0.3 7.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.3 7.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.3 5.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.3 8.0 GO:0022624 proteasome accessory complex(GO:0022624)
0.3 56.0 GO:0005802 trans-Golgi network(GO:0005802)
0.3 8.0 GO:0034451 centriolar satellite(GO:0034451)
0.3 69.6 GO:0014069 postsynaptic density(GO:0014069)
0.3 17.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.3 6.6 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.3 3.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.3 0.8 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.3 11.4 GO:0043679 axon terminus(GO:0043679)
0.2 4.9 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.2 21.5 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.2 24.6 GO:0055037 recycling endosome(GO:0055037)
0.2 4.3 GO:0032590 dendrite membrane(GO:0032590)
0.2 3.3 GO:0005839 proteasome core complex(GO:0005839)
0.2 1.8 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.2 4.1 GO:0010369 chromocenter(GO:0010369)
0.2 8.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.2 5.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 3.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.2 3.2 GO:0002102 podosome(GO:0002102)
0.2 1.1 GO:1990635 proximal dendrite(GO:1990635)
0.2 9.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 0.8 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 26.3 GO:0098793 presynapse(GO:0098793)
0.1 9.7 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 6.5 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 9.4 GO:0043204 perikaryon(GO:0043204)
0.1 0.6 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.7 GO:0016600 flotillin complex(GO:0016600)
0.1 0.7 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 3.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.6 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 31.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 1.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.8 GO:0000796 condensin complex(GO:0000796)
0.1 2.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.9 GO:0045180 basal cortex(GO:0045180)
0.1 6.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 5.2 GO:0005902 microvillus(GO:0005902)
0.1 0.9 GO:0031010 ISWI-type complex(GO:0031010)
0.1 5.0 GO:0005884 actin filament(GO:0005884)
0.1 0.9 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 0.3 GO:0032009 early phagosome(GO:0032009)
0.1 5.0 GO:0005840 ribosome(GO:0005840)
0.1 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 1.9 GO:0031519 PcG protein complex(GO:0031519)
0.1 7.1 GO:0043209 myelin sheath(GO:0043209)
0.0 3.7 GO:0042383 sarcolemma(GO:0042383)
0.0 4.6 GO:0032993 protein-DNA complex(GO:0032993)
0.0 11.0 GO:0043025 neuronal cell body(GO:0043025)
0.0 2.9 GO:0016605 PML body(GO:0016605)
0.0 0.9 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 3.8 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 1.0 GO:0005643 nuclear pore(GO:0005643)
0.0 1.4 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.6 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
9.8 29.5 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
8.8 35.3 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
7.7 30.9 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
5.8 17.5 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
5.5 38.2 GO:0031014 troponin T binding(GO:0031014)
4.9 29.7 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
4.5 31.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
4.2 12.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
4.1 12.3 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
3.9 15.7 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
3.5 21.0 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
3.4 10.2 GO:0001565 phorbol ester receptor activity(GO:0001565)
3.3 9.8 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
3.1 15.3 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
3.0 9.0 GO:0016748 succinyltransferase activity(GO:0016748)
2.9 8.7 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
2.9 14.5 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
2.8 39.4 GO:0051378 serotonin binding(GO:0051378)
2.8 13.8 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
2.6 41.7 GO:0005523 tropomyosin binding(GO:0005523)
2.5 10.0 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
2.4 14.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
2.4 19.0 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
2.2 42.5 GO:0008179 adenylate cyclase binding(GO:0008179)
2.2 6.7 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
2.2 6.6 GO:0030158 protein xylosyltransferase activity(GO:0030158)
2.2 6.6 GO:0015292 uniporter activity(GO:0015292)
2.2 8.6 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
2.1 14.9 GO:0098988 G-protein coupled glutamate receptor activity(GO:0098988)
2.0 6.1 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
2.0 55.0 GO:0031402 sodium ion binding(GO:0031402)
1.9 13.0 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
1.9 14.9 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
1.9 5.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.9 26.0 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
1.8 5.5 GO:0033222 xylose binding(GO:0033222)
1.8 9.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
1.8 11.0 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
1.8 9.1 GO:0030348 syntaxin-3 binding(GO:0030348)
1.8 16.3 GO:0019992 diacylglycerol binding(GO:0019992)
1.8 9.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
1.8 10.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
1.8 10.8 GO:0005138 interleukin-6 receptor binding(GO:0005138)
1.6 39.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
1.6 9.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
1.5 57.0 GO:0005246 calcium channel regulator activity(GO:0005246)
1.5 16.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
1.5 6.0 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
1.5 15.0 GO:0032036 myosin heavy chain binding(GO:0032036)
1.5 4.5 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
1.5 20.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
1.4 34.7 GO:0017075 syntaxin-1 binding(GO:0017075)
1.4 8.6 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
1.4 7.1 GO:0004969 histamine receptor activity(GO:0004969)
1.4 18.4 GO:0045294 alpha-catenin binding(GO:0045294)
1.4 8.3 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
1.3 5.2 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
1.2 8.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
1.2 7.0 GO:0042289 MHC class II protein binding(GO:0042289)
1.2 8.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
1.1 3.4 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
1.1 10.0 GO:0015266 protein channel activity(GO:0015266)
1.1 3.2 GO:0004911 interleukin-2 receptor activity(GO:0004911)
1.1 6.4 GO:0008318 protein prenyltransferase activity(GO:0008318)
1.1 3.2 GO:0034512 box C/D snoRNA binding(GO:0034512)
1.1 6.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
1.0 7.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
1.0 6.0 GO:0032027 myosin light chain binding(GO:0032027)
1.0 6.7 GO:0031433 telethonin binding(GO:0031433)
0.9 2.8 GO:0031770 growth hormone-releasing hormone receptor binding(GO:0031770)
0.9 2.7 GO:0097677 STAT family protein binding(GO:0097677)
0.9 14.8 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.9 25.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.8 8.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.8 7.3 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.8 8.9 GO:0004017 adenylate kinase activity(GO:0004017)
0.8 18.6 GO:0031489 myosin V binding(GO:0031489)
0.8 11.3 GO:0033691 sialic acid binding(GO:0033691)
0.8 4.0 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.8 4.0 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.8 2.4 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.8 16.5 GO:0099589 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.8 16.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.8 3.8 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.7 9.4 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.7 7.2 GO:0022821 potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.7 15.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.7 18.8 GO:0017091 AU-rich element binding(GO:0017091)
0.7 45.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.7 15.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.7 14.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.7 4.7 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.7 3.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.7 4.0 GO:0004994 somatostatin receptor activity(GO:0004994)
0.7 9.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.7 10.4 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.6 5.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.6 5.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.6 2.5 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.6 1.9 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.6 6.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.6 16.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.6 1.8 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.6 3.0 GO:0030280 structural constituent of epidermis(GO:0030280)
0.6 2.9 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.6 2.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.5 3.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.5 4.2 GO:0036122 BMP binding(GO:0036122)
0.5 3.2 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.5 2.6 GO:0004875 complement receptor activity(GO:0004875)
0.5 4.7 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.5 4.4 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.5 7.6 GO:0008143 poly(A) binding(GO:0008143)
0.5 4.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.5 1.9 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.5 3.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.5 10.7 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.5 7.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.5 1.8 GO:0004594 pantothenate kinase activity(GO:0004594)
0.5 1.8 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.5 6.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.4 3.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.4 34.3 GO:0019209 kinase activator activity(GO:0019209)
0.4 1.3 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.4 29.5 GO:0005518 collagen binding(GO:0005518)
0.4 2.1 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.4 2.8 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.4 3.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.4 1.2 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.4 1.9 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.4 1.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.4 1.5 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.4 43.3 GO:0005178 integrin binding(GO:0005178)
0.4 13.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.3 3.1 GO:0015093 manganese ion transmembrane transporter activity(GO:0005384) ferrous iron transmembrane transporter activity(GO:0015093)
0.3 7.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.3 3.7 GO:0005000 vasopressin receptor activity(GO:0005000)
0.3 1.3 GO:0005534 galactose binding(GO:0005534)
0.3 2.0 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.3 6.3 GO:0008373 sialyltransferase activity(GO:0008373)
0.3 32.0 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.3 3.8 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.3 4.4 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.3 1.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.3 6.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.3 34.8 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.3 4.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.3 4.2 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.3 3.6 GO:0008061 chitin binding(GO:0008061)
0.3 342.7 GO:0004984 olfactory receptor activity(GO:0004984)
0.3 2.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.3 7.6 GO:0042605 peptide antigen binding(GO:0042605)
0.3 3.4 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.3 6.4 GO:0003951 NAD+ kinase activity(GO:0003951)
0.2 7.2 GO:0043531 ADP binding(GO:0043531)
0.2 3.7 GO:0001594 trace-amine receptor activity(GO:0001594)
0.2 2.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.2 64.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 2.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 2.7 GO:0005344 oxygen transporter activity(GO:0005344)
0.2 15.3 GO:0030276 clathrin binding(GO:0030276)
0.2 18.3 GO:0051087 chaperone binding(GO:0051087)
0.2 3.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2 1.7 GO:0034511 U3 snoRNA binding(GO:0034511)
0.2 1.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.2 7.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.2 5.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 3.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 1.6 GO:1990239 estrogen receptor activity(GO:0030284) steroid hormone binding(GO:1990239)
0.2 4.2 GO:0004623 phospholipase A2 activity(GO:0004623)
0.2 2.4 GO:0031005 filamin binding(GO:0031005)
0.2 3.9 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.2 13.5 GO:0008013 beta-catenin binding(GO:0008013)
0.2 33.7 GO:0042393 histone binding(GO:0042393)
0.2 13.6 GO:0030165 PDZ domain binding(GO:0030165)
0.2 15.4 GO:0017048 Rho GTPase binding(GO:0017048)
0.2 15.1 GO:0008565 protein transporter activity(GO:0008565)
0.2 23.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 6.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 1.6 GO:0005132 type I interferon receptor binding(GO:0005132)
0.2 2.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.2 3.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 3.5 GO:0019843 rRNA binding(GO:0019843)
0.1 2.7 GO:0030371 translation repressor activity(GO:0030371)
0.1 1.7 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 2.8 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 5.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 15.3 GO:0019207 kinase regulator activity(GO:0019207)
0.1 9.0 GO:0051287 NAD binding(GO:0051287)
0.1 1.4 GO:0008242 omega peptidase activity(GO:0008242)
0.1 3.3 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 5.6 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 7.4 GO:0002039 p53 binding(GO:0002039)
0.1 3.7 GO:0042805 actinin binding(GO:0042805)
0.1 2.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.8 GO:0001671 ATPase activator activity(GO:0001671)
0.1 5.2 GO:0005057 receptor signaling protein activity(GO:0005057)
0.1 4.6 GO:0032947 protein complex scaffold(GO:0032947)
0.1 0.6 GO:0034452 dynactin binding(GO:0034452)
0.1 5.4 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 0.3 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 6.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 11.5 GO:0047485 protein N-terminus binding(GO:0047485)
0.1 0.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 2.0 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 1.9 GO:0005080 protein kinase C binding(GO:0005080)
0.1 3.0 GO:0097110 scaffold protein binding(GO:0097110)
0.1 14.8 GO:0019902 phosphatase binding(GO:0019902)
0.1 6.6 GO:0016247 channel regulator activity(GO:0016247)
0.1 28.4 GO:0003779 actin binding(GO:0003779)
0.1 0.6 GO:0031996 thioesterase binding(GO:0031996)
0.1 2.8 GO:0019894 kinesin binding(GO:0019894)
0.1 3.2 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 0.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 2.5 GO:0051117 ATPase binding(GO:0051117)
0.1 0.8 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.1 4.0 GO:0044325 ion channel binding(GO:0044325)
0.1 2.1 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 2.1 GO:0030332 cyclin binding(GO:0030332)
0.1 1.1 GO:0070064 proline-rich region binding(GO:0070064)
0.1 4.2 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 2.4 GO:0004177 aminopeptidase activity(GO:0004177)
0.1 3.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 3.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 1.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 8.9 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.1 2.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 1.5 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.2 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 18.3 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.2 GO:0035240 dopamine binding(GO:0035240)
0.0 8.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 2.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 2.6 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 4.9 GO:0005125 cytokine activity(GO:0005125)
0.0 1.5 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 8.3 GO:0030246 carbohydrate binding(GO:0030246)
0.0 2.8 GO:0005179 hormone activity(GO:0005179)
0.0 4.0 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0042288 MHC class I protein binding(GO:0042288)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 19.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
1.0 50.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.9 3.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.8 5.0 PID EPHB FWD PATHWAY EPHB forward signaling
0.6 24.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.5 20.6 PID IL23 PATHWAY IL23-mediated signaling events
0.5 14.1 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.5 3.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.4 4.4 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.4 7.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.4 12.4 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.4 21.5 PID TNF PATHWAY TNF receptor signaling pathway
0.4 13.8 PID BCR 5PATHWAY BCR signaling pathway
0.4 20.4 PID FOXO PATHWAY FoxO family signaling
0.4 8.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.4 5.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.4 19.3 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.4 18.9 PID CDC42 PATHWAY CDC42 signaling events
0.3 8.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.3 5.7 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.3 11.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.3 10.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.3 6.0 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.2 2.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 7.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.2 2.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 11.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.2 2.6 PID ALK2 PATHWAY ALK2 signaling events
0.2 4.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.2 4.8 PID RHOA PATHWAY RhoA signaling pathway
0.2 1.7 PID IL27 PATHWAY IL27-mediated signaling events
0.2 2.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 6.4 PID P53 REGULATION PATHWAY p53 pathway
0.2 8.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.2 8.0 PID AP1 PATHWAY AP-1 transcription factor network
0.2 3.1 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.2 10.5 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.2 3.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.2 3.5 PID AURORA A PATHWAY Aurora A signaling
0.2 9.0 PID E2F PATHWAY E2F transcription factor network
0.1 5.7 PID PLK1 PATHWAY PLK1 signaling events
0.1 1.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 7.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 2.5 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 2.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 0.9 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 4.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 1.9 PID CONE PATHWAY Visual signal transduction: Cones
0.1 18.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 0.8 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 2.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 3.1 PID CMYB PATHWAY C-MYB transcription factor network
0.1 2.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.4 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 43.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
2.7 105.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
2.5 20.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
2.5 40.1 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
1.9 50.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
1.8 17.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
1.7 18.8 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
1.6 31.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
1.6 62.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
1.2 6.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
1.2 16.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
1.1 21.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
1.1 19.0 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
1.0 2.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
1.0 15.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
1.0 6.8 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
1.0 12.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.9 2.7 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.8 44.7 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.8 17.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.8 13.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.8 10.9 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.7 10.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.7 7.8 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.7 18.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.7 15.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.7 3.4 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.7 18.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.6 6.9 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.6 5.9 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.6 2.8 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.5 8.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.5 9.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.5 6.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.5 11.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.5 36.8 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.5 50.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.5 9.4 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.5 23.3 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.5 4.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.4 6.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.4 8.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.4 4.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.4 9.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.4 6.1 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.4 2.3 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.4 6.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.4 29.0 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.4 4.0 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.4 6.1 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.3 5.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.3 5.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.3 4.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.3 3.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.3 2.5 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.2 3.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2 8.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 6.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 3.6 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 6.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 3.8 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.2 6.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 3.3 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.2 2.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.2 34.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.2 8.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 4.2 REACTOME PI3K EVENTS IN ERBB4 SIGNALING Genes involved in PI3K events in ERBB4 signaling
0.2 3.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.8 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 3.6 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.1 2.8 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 3.3 REACTOME KINESINS Genes involved in Kinesins
0.1 1.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 4.5 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.1 5.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 8.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 2.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 1.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 4.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 2.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.9 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.0 0.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.8 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.9 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.8 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 1.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.1 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 0.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts