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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Foxo6

Z-value: 0.48

Motif logo

Transcription factors associated with Foxo6

Gene Symbol Gene ID Gene Info
ENSRNOG00000032639 forkhead box O6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxo6rn6_v1_chr5_-_139227196_139227196-0.211.2e-04Click!

Activity profile of Foxo6 motif

Sorted Z-values of Foxo6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_49109981 20.37 ENSRNOT00000019933
tetratricopeptide repeat domain 36
chr2_+_93758919 12.98 ENSRNOT00000077782
fatty acid binding protein 12
chr14_+_22517774 12.85 ENSRNOT00000047655
UDP-glucuronosyltransferase 2 family, member 37
chr14_-_19072677 12.19 ENSRNOT00000060548
similar to alpha-fetoprotein
chr5_-_54482159 11.01 ENSRNOT00000050030
similar to RAN protein
chr18_-_15089988 10.86 ENSRNOT00000074116
meprin A subunit beta
chr5_-_33664435 8.72 ENSRNOT00000009047
WW domain containing E3 ubiquitin protein ligase 1
chr9_+_77320726 8.44 ENSRNOT00000068450
sperm associated antigen 16
chr2_+_248649441 8.28 ENSRNOT00000067165
kynurenine aminotransferase 3
chr11_+_52828116 8.28 ENSRNOT00000035340
coiled-coil domain containing 54
chr2_+_23289374 8.27 ENSRNOT00000090666
ENSRNOT00000032783
dimethylglycine dehydrogenase
chr15_+_80040842 8.04 ENSRNOT00000043065
similar to RIKEN cDNA 4921530L21
chr3_+_143151739 7.69 ENSRNOT00000006850
cystatin 13
chr6_-_86223052 7.62 ENSRNOT00000046828
fibrous sheath CABYR binding protein
chr1_+_101474334 7.61 ENSRNOT00000064245
tubby-like protein 2
chr1_-_224389389 7.60 ENSRNOT00000077408
ENSRNOT00000050010
integral membrane transport protein UST4r
chr2_+_188543137 7.49 ENSRNOT00000027850
mucin 1, cell surface associated
chr1_+_201687758 7.30 ENSRNOT00000093308
deleted in malignant brain tumors 1
chr10_-_107114271 7.25 ENSRNOT00000004035
dynein, axonemal, heavy chain 17
chr1_+_189359853 7.19 ENSRNOT00000055083
acyl-CoA synthetase medium-chain family member 1
chr2_+_147006830 7.10 ENSRNOT00000080780

chrX_+_45965301 6.95 ENSRNOT00000005141
family with sequence similarity 47, member A
chr5_-_173484986 6.83 ENSRNOT00000064207
ENSRNOT00000055319
tubulin tyrosine ligase like 10
chr4_+_120671489 6.76 ENSRNOT00000029125
monoglyceride lipase
chr1_-_253000760 6.62 ENSRNOT00000030024
solute carrier family 16, member 12
chr3_-_156905892 6.47 ENSRNOT00000022424
elastin microfibril interfacer 3
chr2_-_196415530 6.43 ENSRNOT00000064238
similar to hypothetical protein FLJ20519
chr7_+_40316639 6.26 ENSRNOT00000080150
similar to hypothetical protein FLJ35821
chr17_+_8558827 6.22 ENSRNOT00000016187
interleukin 9
chr19_+_85606 6.22 ENSRNOT00000015724
carboxylesterase 2E
chr8_-_40883880 6.11 ENSRNOT00000075593
disks large homolog 5-like
chrX_+_15669191 6.10 ENSRNOT00000013553
MAGI family member, X-linked
chr1_-_143398093 5.90 ENSRNOT00000078916
fibronectin type III and SPRY domain containing 2
chrX_+_25737292 5.66 ENSRNOT00000004893
similar to RIKEN cDNA 4933400A11
chr4_+_22084954 5.37 ENSRNOT00000090968
carnitine O-octanoyltransferase
chr10_-_87564327 5.20 ENSRNOT00000064760
ENSRNOT00000068237
similar to keratin associated protein 4-7
chr1_+_279896973 5.06 ENSRNOT00000068119
pancreatic lipase related protein 2
chr5_+_64412895 4.97 ENSRNOT00000010561
muscle-related coiled-coil protein
chr9_-_117484262 4.96 ENSRNOT00000091931

chr4_+_153876149 4.91 ENSRNOT00000018083
solute carrier family 6 member 13
chr16_+_68633720 4.87 ENSRNOT00000081838
sperm motility kinase-like
chr20_+_915079 4.87 ENSRNOT00000074181
olfactory receptor 14J1-like
chr1_-_171979933 4.81 ENSRNOT00000026744
cytochrome b5 reductase 2
chr18_+_29124428 4.72 ENSRNOT00000073131
IgA-inducing protein
chr11_+_88095170 4.71 ENSRNOT00000041557
coiled-coil domain containing 116
chr17_+_59714657 4.70 ENSRNOT00000035675
similar to ankyrin repeat domain 26
chrX_-_37705263 4.59 ENSRNOT00000043666
mitogen-activated protein kinase kinase kinase 15
chr1_-_102826965 4.48 ENSRNOT00000078692
serum amyloid A4
chr1_+_125124743 4.43 ENSRNOT00000021530
myotubularin related protein 10
chrX_+_43183381 4.41 ENSRNOT00000039874
melanoma antigen, family A, 8
chr13_+_82552550 4.40 ENSRNOT00000003817
ENSRNOT00000076722
ENSRNOT00000076607
solute carrier family 19 member 2
chr2_-_228665279 4.36 ENSRNOT00000055648
similar to T-cell activation Rho GTPase-activating protein isoform b
chr1_-_193328371 4.29 ENSRNOT00000019304
ENSRNOT00000031770
ENSRNOT00000019309
Rho GTPase activating protein 17
chrX_-_143558521 4.25 ENSRNOT00000056598
hypothetical protein LOC688842
chr1_+_177183209 4.22 ENSRNOT00000085326
MICAL C-terminal like
chr19_-_26006970 4.17 ENSRNOT00000004570
glutaryl-CoA dehydrogenase
chr10_-_41491554 3.90 ENSRNOT00000035759
uncharacterized LOC102552619
chr5_-_160282810 3.79 ENSRNOT00000076160
ENSRNOT00000016352
DNA-damage inducible protein 2
chr10_-_90415070 3.72 ENSRNOT00000055179
integrin subunit alpha 2b
chr17_+_38929045 3.59 ENSRNOT00000081739
prolactin family 7, subfamily d, member 1
chr17_-_42740021 3.45 ENSRNOT00000023063
Prolactin family 3, subfamily a, member 1
chr10_+_13230158 3.42 ENSRNOT00000075648
common salivary protein 1
chr1_-_228558593 3.33 ENSRNOT00000028606
olfactory receptor 326
chr1_+_101012822 3.32 ENSRNOT00000027809
related RAS viral (r-ras) oncogene homolog
chr3_+_61756148 3.30 ENSRNOT00000002134
metaxin 2
chr14_-_72122158 3.23 ENSRNOT00000064495
C1q and tumor necrosis factor related protein 7
chr1_+_282694906 3.06 ENSRNOT00000074303
carboxylesterase 2C
chr18_-_399242 3.01 ENSRNOT00000045926
coagulation factor VIII
chr17_-_57765652 3.01 ENSRNOT00000044132
similar to isopentenyl-diphosphate delta isomerase 2
chr1_+_261464063 2.96 ENSRNOT00000082839

chr3_+_75299283 2.77 ENSRNOT00000013328
olfactory receptor 555
chr5_-_153737161 2.70 ENSRNOT00000073506
noncompact myelin associated protein
chr17_-_57394985 2.69 ENSRNOT00000019968
enhancer of polycomb homolog 1
chr17_+_45670284 2.67 ENSRNOT00000086536
olfactory receptor 1660
chr15_+_44329464 2.61 ENSRNOT00000044151

chr2_-_140464607 2.61 ENSRNOT00000058190
NADH:ubiquinone oxidoreductase subunit C1
chr8_+_99636749 2.57 ENSRNOT00000086524
phospholipid scramblase 1
chr15_+_46196771 2.53 ENSRNOT00000059212
defensin beta 43
chr20_+_29445510 2.51 ENSRNOT00000044805
DnaJ heat shock protein family (Hsp40) member B12
chrX_+_24059516 2.49 ENSRNOT00000049256
hypothetical protein LOC685747
chrX_-_106085878 2.44 ENSRNOT00000049735
preferentially expressed antigen in melanoma
chr7_-_36408588 2.38 ENSRNOT00000063946
CASP2 and RIPK1 domain containing adaptor with death domain
chr7_+_97559841 2.37 ENSRNOT00000007326
zinc fingers and homeoboxes 2
chr20_+_734642 2.30 ENSRNOT00000073543
olfactory receptor 1688
chr3_+_72063504 2.26 ENSRNOT00000066606
BTB domain containing 18
chr3_-_79121620 2.25 ENSRNOT00000087141
olfactory receptor 741
chr1_-_275876329 2.25 ENSRNOT00000047903
glycerol-3-phosphate acyltransferase, mitochondrial
chr1_-_247088012 2.10 ENSRNOT00000020464
spermatogenesis associated 6-like
chr8_-_17860348 2.08 ENSRNOT00000046875
olfactory receptor 1118
chr9_-_99659425 2.05 ENSRNOT00000051686
olfactory receptor 1343
chr4_+_82637411 2.04 ENSRNOT00000048225
LRRGT00062
chr3_-_121836086 2.01 ENSRNOT00000006113
interleukin 1 alpha
chr3_-_74342719 1.94 ENSRNOT00000013060
olfactory receptor 519
chr16_-_49453394 1.93 ENSRNOT00000041617
Lrp2 binding protein
chr10_+_111716966 1.91 ENSRNOT00000070942
vomeronasal type-2 receptor 26-like
chr2_-_206842724 1.83 ENSRNOT00000086252

chr5_+_12406988 1.82 ENSRNOT00000061899
similar to 60S acidic ribosomal protein P2
chr3_+_123776181 1.81 ENSRNOT00000090764
ENSRNOT00000034146
mitochondrial antiviral signaling protein
chr7_+_120465130 1.73 ENSRNOT00000016077
protein interacting with PRKCA 1
chr14_+_7949239 1.70 ENSRNOT00000044617
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4-like 1
chr8_+_42284654 1.64 ENSRNOT00000043810
olfactory receptor 8B3-like
chr3_-_76114902 1.59 ENSRNOT00000071564
olfactory receptor 5L1-like
chr13_-_45040593 1.56 ENSRNOT00000004908
lactase
chr7_-_139784444 1.56 ENSRNOT00000084656

chr1_-_149441437 1.53 ENSRNOT00000041780
vomeronasal 2 receptor, 41
chr14_-_21615488 1.51 ENSRNOT00000002667
variable coding sequence A2
chr17_+_3210130 1.51 ENSRNOT00000072334
similar to cathepsin 1 precursor
chr6_-_26138414 1.45 ENSRNOT00000034712
mitochondrial ribosomal protein L33
chr4_+_62019970 1.44 ENSRNOT00000013133
aldose reductase-related protein 1-like
chr4_-_1752548 1.43 ENSRNOT00000071677
olfactory receptor 150-like
chr10_-_6870011 1.40 ENSRNOT00000003439
similar to CG4768-PA
chr7_+_13631975 1.38 ENSRNOT00000083548
olfactory receptor 1084
chr3_-_78717401 1.35 ENSRNOT00000008676
olfactory receptor 720
chr2_+_115092263 1.30 ENSRNOT00000064455
olfactory receptor 150-like
chr8_-_3882077 1.29 ENSRNOT00000071085
vomeronasal 2 receptor, 25
chr15_+_35571103 1.28 ENSRNOT00000085376
olfactory receptor 1293
chr9_-_17120677 1.27 ENSRNOT00000025769
Yip1 domain family, member 3
chr1_-_63571794 1.25 ENSRNOT00000046049
vomeronasal 2 receptor, 30
chr2_-_127781003 1.24 ENSRNOT00000050764
major facilitator superfamily domain containing 8
chr1_-_242152834 1.24 ENSRNOT00000071614
ENSRNOT00000020412
frataxin
chr4_+_45854403 1.23 ENSRNOT00000084484
similar to protein disulfide isomerase-associated 6
chr4_-_167180656 1.16 ENSRNOT00000049487
taste receptor, type 2, member 103
chr19_+_23832780 1.10 ENSRNOT00000045060

chr6_-_141715846 1.07 ENSRNOT00000044966

chr1_-_150101177 1.02 ENSRNOT00000042931
olfactory receptor 24
chr10_+_87782376 0.93 ENSRNOT00000017415
hypothetical protein LOC680396
chr9_+_17120759 0.88 ENSRNOT00000025787
RNA polymerase I subunit C
chr1_+_60044985 0.88 ENSRNOT00000079924
vomeronasal 1 receptor 6
chr8_+_44638556 0.87 ENSRNOT00000044669
vomeronasal 2 receptor, 3
chr1_-_149175205 0.85 ENSRNOT00000089091
ENSRNOT00000045611
ENSRNOT00000089015
vomeronasal 2 receptor, 42
chr7_+_6096690 0.84 ENSRNOT00000051694
olfactory receptor 1006
chr5_+_116973159 0.83 ENSRNOT00000046475
uncharacterized LOC100912024
chr3_+_75848904 0.83 ENSRNOT00000042996
olfactory receptor 583
chr13_+_96195836 0.82 ENSRNOT00000042547
similar to basic transcription factor 3
chr14_+_779169 0.82 ENSRNOT00000052336
ENSRNOT00000073211
ENSRNOT00000086687

chr3_+_73988945 0.81 ENSRNOT00000050404
olfactory receptor 515
chr3_+_15823220 0.81 ENSRNOT00000075496
olfactory receptor 398
chr7_+_9294709 0.78 ENSRNOT00000048396
olfactory receptor 1065
chr1_-_172215730 0.74 ENSRNOT00000055175
olfactory receptor 244
chr19_-_37216572 0.74 ENSRNOT00000020405
TNFRSF1A-associated via death domain
chr15_+_18941431 0.74 ENSRNOT00000092092

chr16_-_75028977 0.73 ENSRNOT00000058071
defensin beta 13
chr15_-_27408258 0.71 ENSRNOT00000043588
similar to Cytochrome c, somatic
chr1_-_69016426 0.68 ENSRNOT00000093436

chr9_+_44491177 0.67 ENSRNOT00000075242
mitochondrial ribosomal protein L30
chr1_-_171045419 0.63 ENSRNOT00000047239
olfactory receptor 224
chr20_+_8484311 0.61 ENSRNOT00000050041
ribosomal protein S20-like
chr4_+_121760773 0.60 ENSRNOT00000087069
vomeronasal 1 receptor 92
chr3_+_76179214 0.56 ENSRNOT00000071281
similar to olfactory receptor 1161
chr3_-_73839527 0.55 ENSRNOT00000080756
olfactory receptor 508
chr12_-_47987255 0.54 ENSRNOT00000074000
ubiquitin protein ligase E3B
chr1_+_170796271 0.50 ENSRNOT00000042820
olfactory receptor 210
chr14_+_22192970 0.50 ENSRNOT00000041514
ENSRNOT00000002704
UDP glucuronosyltransferase 2 family, polypeptide A1
chr10_-_60573129 0.48 ENSRNOT00000083428
olfactory receptor 1499
chr3_+_19071980 0.47 ENSRNOT00000079487
immunoglobulin kappa variable 4-81
chrX_-_75224268 0.43 ENSRNOT00000089809
ATP binding cassette subfamily B member 7
chr4_-_103258134 0.42 ENSRNOT00000086827

chr7_-_116106368 0.41 ENSRNOT00000035678
lymphocyte antigen 6 complex, locus K
chr11_-_65350442 0.40 ENSRNOT00000003773
G protein-coupled receptor 156
chrX_-_156999650 0.40 ENSRNOT00000083557
signal sequence receptor subunit 4
chr17_+_70586394 0.37 ENSRNOT00000025550
RNA binding motif protein 17
chr1_-_60332899 0.34 ENSRNOT00000078636
vomeronasal type-1 receptor 4-like
chr8_+_41358307 0.32 ENSRNOT00000071307
olfactory receptor 143-like
chr8_+_5676665 0.32 ENSRNOT00000012310
matrix metallopeptidase 3
chr4_+_122124451 0.31 ENSRNOT00000052101
vomeronasal 1 receptor A14
chr16_-_20641908 0.30 ENSRNOT00000026846
elongation factor for RNA polymerase II
chr11_+_42945084 0.30 ENSRNOT00000002292
crystallin beta-gamma domain containing 3
chr3_-_12029877 0.30 ENSRNOT00000022327
solute carrier family 2 member 8
chr7_+_9262982 0.29 ENSRNOT00000047647
olfactory receptor 1063
chr1_-_73961432 0.27 ENSRNOT00000035435
NLR family, pyrin domain containing 4B
chr4_-_167068838 0.26 ENSRNOT00000029713
taste receptor, type 2, member 125
chr15_+_75067297 0.25 ENSRNOT00000057931
similar to 60S acidic ribosomal protein P2
chr15_+_28413461 0.23 ENSRNOT00000060521
transmembrane protein 253
chr13_-_35933243 0.22 ENSRNOT00000039074
transmembrane protein 177
chr7_-_17859653 0.22 ENSRNOT00000030164
zinc finger and SCAN domain containing 4F
chr3_+_15688992 0.21 ENSRNOT00000045037
olfactory receptor 395
chr3_+_19366370 0.21 ENSRNOT00000086557

chr1_-_170916059 0.20 ENSRNOT00000041974
olfactory receptor 217
chr12_+_41200718 0.20 ENSRNOT00000038426
ENSRNOT00000048450
ENSRNOT00000067176
2'-5' oligoadenylate synthetase 1A
chr3_-_113057791 0.18 ENSRNOT00000056190
transglutaminase 7-like 1
chr9_+_101222846 0.16 ENSRNOT00000074328
vomeronasal 1 receptor 64
chr4_+_87440996 0.15 ENSRNOT00000074184
vomeronasal 1 receptor 68
chr1_-_74638587 0.15 ENSRNOT00000046047
vomeronasal 2 receptor, 30
chr4_+_166993669 0.09 ENSRNOT00000045376
taste receptor, type 2, member 109
chr2_+_87957363 0.06 ENSRNOT00000047881
LRRGT00038
chr4_+_25635765 0.05 ENSRNOT00000009340
GTP binding protein 10
chr1_-_193700673 0.04 ENSRNOT00000071314
polyadenylate-binding protein-interacting protein 2-like 1
chr18_-_71614980 0.03 ENSRNOT00000032563
peroxisomal biogenesis factor 19-like
chr19_+_25946979 0.02 ENSRNOT00000004027
GADD45G interacting protein 1
chr1_-_63457134 0.01 ENSRNOT00000083436

chr18_+_61377051 0.01 ENSRNOT00000066659
O-acyltransferase like
chr1_-_60281386 0.00 ENSRNOT00000092184
vomeronasal 1 receptor 10

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxo6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.4 GO:0051012 microtubule sliding(GO:0051012)
2.8 8.3 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
2.3 6.8 GO:0018094 protein polyglycylation(GO:0018094)
1.7 8.3 GO:0097052 L-kynurenine metabolic process(GO:0097052)
1.5 4.4 GO:0071934 thiamine transmembrane transport(GO:0071934)
1.3 7.6 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
1.2 4.6 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
1.1 5.4 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.9 7.5 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.9 2.7 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.8 3.0 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.7 5.1 GO:0019374 galactolipid metabolic process(GO:0019374)
0.7 7.6 GO:0015747 urate transport(GO:0015747)
0.7 2.0 GO:1904444 regulation of establishment of Sertoli cell barrier(GO:1904444)
0.6 10.8 GO:0033753 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
0.5 1.8 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.4 4.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.4 1.2 GO:0018282 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.4 6.2 GO:0032754 positive regulation of interleukin-5 production(GO:0032754)
0.4 2.6 GO:0070782 phosphatidylserine biosynthetic process(GO:0006659) phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.4 7.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.3 1.7 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.3 2.5 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.3 2.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.3 1.6 GO:0010045 response to nickel cation(GO:0010045)
0.3 2.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.2 4.9 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.2 10.9 GO:1901998 toxin transport(GO:1901998)
0.2 6.6 GO:0072337 modified amino acid transport(GO:0072337)
0.2 4.9 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.2 2.4 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1 2.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 3.6 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.1 4.8 GO:0016126 sterol biosynthetic process(GO:0016126)
0.1 7.2 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 4.5 GO:0006953 acute-phase response(GO:0006953)
0.1 0.7 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.1 3.7 GO:0070527 platelet aggregation(GO:0070527)
0.1 2.0 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.3 GO:0071460 negative regulation of hydrogen peroxide metabolic process(GO:0010727) cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 2.4 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 1.2 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.9 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 1.2 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 27.7 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 3.3 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 1.5 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.4 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 3.3 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.3 GO:0007141 male meiosis I(GO:0007141)
0.0 4.8 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)
0.0 3.1 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 2.9 GO:0007018 microtubule-based movement(GO:0007018)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 8.4 GO:1990716 axonemal central apparatus(GO:1990716)
0.7 2.7 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.7 12.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.4 7.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.3 6.8 GO:0043196 varicosity(GO:0043196)
0.3 4.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 4.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 7.2 GO:0030286 dynein complex(GO:0030286)
0.1 2.7 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.1 3.7 GO:0008305 integrin complex(GO:0008305)
0.1 0.4 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 0.3 GO:0035363 histone locus body(GO:0035363)
0.1 6.8 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 0.9 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 7.2 GO:0072562 blood microparticle(GO:0072562)
0.1 2.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 3.2 GO:0005581 collagen trimer(GO:0005581)
0.0 1.7 GO:0016235 aggresome(GO:0016235)
0.0 6.2 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.1 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 8.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 4.3 GO:0005923 bicellular tight junction(GO:0005923)
0.0 2.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 34.5 GO:0005615 extracellular space(GO:0005615)
0.0 3.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 4.6 GO:0031012 extracellular matrix(GO:0031012)
0.0 4.6 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.9 GO:0045095 keratin filament(GO:0045095)
0.0 0.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.6 GO:0005903 brush border(GO:0005903)
0.0 7.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.8 GO:0070735 protein-glycine ligase activity(GO:0070735)
2.1 8.3 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
1.8 5.4 GO:0016414 carnitine O-octanoyltransferase activity(GO:0008458) O-octanoyltransferase activity(GO:0016414)
1.5 4.4 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) uptake transmembrane transporter activity(GO:0015563)
1.0 7.3 GO:0035375 zymogen binding(GO:0035375)
0.9 7.2 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.8 4.9 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.8 4.8 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.8 3.1 GO:0047619 acylcarnitine hydrolase activity(GO:0047619)
0.8 7.6 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.7 9.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.6 3.7 GO:0070051 fibrinogen binding(GO:0070051)
0.5 1.6 GO:0017042 glycosylceramidase activity(GO:0017042)
0.5 8.3 GO:0005542 folic acid binding(GO:0005542)
0.4 13.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.4 6.6 GO:0051184 cofactor transporter activity(GO:0051184)
0.4 2.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.3 4.9 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.3 3.1 GO:0070513 death domain binding(GO:0070513)
0.3 4.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.3 1.8 GO:0050700 CARD domain binding(GO:0050700)
0.2 2.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 1.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.7 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 1.8 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 2.0 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.9 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 6.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 4.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 7.5 GO:0002039 p53 binding(GO:0002039)
0.1 7.2 GO:0003777 microtubule motor activity(GO:0003777)
0.1 9.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.2 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 2.4 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 2.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 3.3 GO:0019003 GDP binding(GO:0019003)
0.1 20.5 GO:0005549 odorant binding(GO:0005549)
0.0 8.2 GO:0005125 cytokine activity(GO:0005125)
0.0 8.7 GO:0016874 ligase activity(GO:0016874)
0.0 3.0 GO:0005507 copper ion binding(GO:0005507)
0.0 4.6 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 7.7 GO:0003924 GTPase activity(GO:0003924)
0.0 0.6 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.3 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 1.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.9 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.2 8.7 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 3.7 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 4.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 7.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 3.3 PID RAS PATHWAY Regulation of Ras family activation
0.1 2.0 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 13.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 7.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 3.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 2.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 4.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.3 1.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 5.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.2 3.7 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2 3.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 1.8 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.2 3.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 5.1 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.1 7.7 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 4.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.7 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 4.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 2.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 0.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 2.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 5.5 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.0 0.9 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 2.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 4.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.4 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.3 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery