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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Foxl1

Z-value: 0.28

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Transcription factors associated with Foxl1

Gene Symbol Gene ID Gene Info
ENSRNOG00000047125 forkhead box L1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxl1rn6_v1_chr19_+_53055745_53055745-0.141.1e-02Click!

Activity profile of Foxl1 motif

Sorted Z-values of Foxl1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_41212072 12.66 ENSRNOT00000085596
protein phosphatase 1, regulatory subunit 3A
chr14_+_26662965 11.29 ENSRNOT00000002621
trans-2,3-enoyl-CoA reductase-like
chr11_-_32858830 9.11 ENSRNOT00000002313
runt-related transcription factor 1
chr17_+_43734461 4.70 ENSRNOT00000072564
histone cluster 1, H1d
chr17_-_43640387 4.36 ENSRNOT00000087731
histone cluster 1 H1 family member c
chr3_+_111135021 3.67 ENSRNOT00000018970
delta like canonical Notch ligand 4
chr19_-_49448072 2.31 ENSRNOT00000014997
C-x(9)-C motif containing 2
chr9_-_71798265 1.90 ENSRNOT00000043766
crystallin, gamma B
chr3_+_73344447 1.06 ENSRNOT00000045693
olfactory receptor 471
chr2_+_209849848 1.01 ENSRNOT00000086836
potassium voltage-gated channel subfamily A member 2
chr4_-_51931112 0.98 ENSRNOT00000080575
protection of telomeres 1
chr3_+_73366155 0.36 ENSRNOT00000044979
olfactory receptor 473
chr15_-_36321572 0.13 ENSRNOT00000073934

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxl1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 9.1 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
1.2 3.7 GO:1903588 blood vessel lumenization(GO:0072554) negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
1.1 9.1 GO:0016584 nucleosome positioning(GO:0016584)
0.7 11.3 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.3 1.0 GO:0060383 positive regulation of DNA strand elongation(GO:0060383)
0.3 1.9 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.2 1.0 GO:0021633 optic nerve structural organization(GO:0021633)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 4.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 1.0 GO:0070187 telosome(GO:0070187)
0.1 9.1 GO:0005604 basement membrane(GO:0005604)
0.1 1.0 GO:0044224 juxtaparanode region of axon(GO:0044224)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.7 GO:0032564 dATP binding(GO:0032564)
0.3 9.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 1.0 GO:1990955 G-rich single-stranded DNA binding(GO:1990955)
0.2 11.3 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.2 3.7 GO:0005112 Notch binding(GO:0005112)
0.1 1.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.0 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 4.4 GO:0031490 chromatin DNA binding(GO:0031490)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 12.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 9.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 3.7 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.0 PID TELOMERASE PATHWAY Regulation of Telomerase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 9.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.3 3.7 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.0 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels