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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Foxj3_Tbl1xr1

Z-value: 3.21

Motif logo

Transcription factors associated with Foxj3_Tbl1xr1

Gene Symbol Gene ID Gene Info
ENSRNOG00000061851 forkhead box J3
ENSRNOG00000011216 transducin (beta)-like 1 X-linked receptor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxj3rn6_v1_chr5_+_138605793_138605793-0.611.8e-34Click!
Tbl1xr1rn6_v1_chr2_+_107233054_1072330540.123.8e-02Click!

Activity profile of Foxj3_Tbl1xr1 motif

Sorted Z-values of Foxj3_Tbl1xr1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_223029559 111.67 ENSRNOT00000045584

chr4_-_170912629 106.61 ENSRNOT00000055691
endoplasmic reticulum protein 27
chr4_+_69435703 104.68 ENSRNOT00000065485
uncharacterized LOC100911271
chr5_-_60191941 97.22 ENSRNOT00000033373
paired box 5
chr4_+_70614524 92.97 ENSRNOT00000041100
protease, serine 3
chr11_+_86094567 90.03 ENSRNOT00000086514
lambda-chain C1-region-like
chr13_+_82369493 88.57 ENSRNOT00000003733
selectin L
chr1_-_259287684 88.17 ENSRNOT00000054724
cytochrome P450, family 2, subfamily c, polypeptide 22
chr3_+_17546566 87.97 ENSRNOT00000050825

chr3_+_16413080 86.14 ENSRNOT00000040386
Ig kappa chain V19-17-like
chr4_+_163349125 85.84 ENSRNOT00000084823
killer cell lectin-like receptor, family E, member 1
chr4_+_69457472 84.62 ENSRNOT00000067597
T cell receptor beta, variable 19
chr11_+_86092468 83.21 ENSRNOT00000057971
lambda-chain C1-region-like
chr4_+_70572942 83.18 ENSRNOT00000051964

chr4_+_70776046 81.20 ENSRNOT00000040403
protease, serine 1
chr11_+_54619129 80.72 ENSRNOT00000059924
T cell receptor associated transmembrane adaptor 1
chr4_-_70628470 80.10 ENSRNOT00000029319
trypsin 5
chr4_+_69403735 75.22 ENSRNOT00000082012
T cell receptor beta, variable 13-1
chr2_-_216443518 74.76 ENSRNOT00000022496
amylase, alpha 1A
chr2_-_203680083 74.63 ENSRNOT00000021268
Cd2 molecule
chr4_-_69196430 74.00 ENSRNOT00000017673
Trypsin V-A
chr2_-_30458542 73.13 ENSRNOT00000072926
NLR family, apoptosis inhibitory protein 6
chr4_+_109497962 73.03 ENSRNOT00000057869
regenerating family member 1 alpha
chr14_+_22937421 71.56 ENSRNOT00000065079
similar to Expressed sequence AI788959
chr15_+_32817343 68.26 ENSRNOT00000073853

chr10_+_94944436 68.03 ENSRNOT00000078968
mast cell immunoglobulin-like receptor 1
chr13_-_56877611 67.28 ENSRNOT00000079040
ENSRNOT00000017195
complement factor H-related 1
chr15_+_31417147 66.98 ENSRNOT00000092182

chr2_-_216348194 66.13 ENSRNOT00000087839
pancreatic alpha-amylase-like
chr4_+_69384145 66.09 ENSRNOT00000084834
T cell receptor beta, variable 13-2
chr6_-_138508753 66.05 ENSRNOT00000006888
immunoglobulin heavy constant mu
chr16_-_31301880 65.22 ENSRNOT00000084847
ENSRNOT00000083943

chr3_+_17107861 64.97 ENSRNOT00000043097

chr4_-_157433467 64.36 ENSRNOT00000028965
lymphocyte activating 3
chr1_+_198744050 64.35 ENSRNOT00000024404
integrin subunit alpha L
chr3_+_17889972 64.28 ENSRNOT00000073021

chr4_-_163402561 64.27 ENSRNOT00000091890
killer cell lectin like receptor K1
chr1_-_197821936 64.14 ENSRNOT00000055027
CD19 molecule
chr10_+_70417108 64.11 ENSRNOT00000079325
schlafen 4
chr11_-_60180031 64.09 ENSRNOT00000043020
ENSRNOT00000093731
germinal center-associated, signaling and motility
chr10_-_34242985 63.93 ENSRNOT00000046438
similar to novel protein
chr13_-_55173692 62.84 ENSRNOT00000064785
ENSRNOT00000029878
ENSRNOT00000029865
ENSRNOT00000060292
ENSRNOT00000000814
protein tyrosine phosphatase, receptor type, C
chr4_-_103024841 62.58 ENSRNOT00000090283

chr4_-_70747226 62.38 ENSRNOT00000044960
anionic trypsin-2-like
chrX_+_15378789 62.12 ENSRNOT00000029272
GATA binding protein 1
chr14_+_17195014 62.02 ENSRNOT00000031667
C-X-C motif chemokine ligand 11
chr7_+_118692851 61.38 ENSRNOT00000091911
apolipoprotein L3-like
chr6_-_140216072 60.92 ENSRNOT00000072365

chr2_+_186685104 60.50 ENSRNOT00000057022
Cd5 molecule-like
chr4_-_164051812 60.08 ENSRNOT00000085719

chr17_+_47870611 59.90 ENSRNOT00000078555

chr3_+_16846412 59.81 ENSRNOT00000074266

chr2_-_216382244 59.71 ENSRNOT00000086695
ENSRNOT00000087259
pancreatic alpha-amylase-like
chr6_+_139209936 59.63 ENSRNOT00000087620

chr10_-_56506446 59.55 ENSRNOT00000021357
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr15_+_30570483 59.49 ENSRNOT00000071740

chr13_-_61591139 59.48 ENSRNOT00000005324
regulator of G-protein signaling 18
chr10_+_31880918 59.12 ENSRNOT00000059448
T-cell immunoglobulin and mucin domain containing 4
chr6_-_127337791 59.07 ENSRNOT00000032015
interferon, alpha-inducible protein 27 like 2B
chrX_+_78372257 58.72 ENSRNOT00000046164
G protein-coupled receptor 174
chr20_-_4863198 58.13 ENSRNOT00000001108
lymphotoxin beta
chr12_-_46889082 57.93 ENSRNOT00000001525
phospholipase A2 group IB
chr3_+_19045214 57.78 ENSRNOT00000070878

chr4_-_163890801 57.46 ENSRNOT00000081946
immunoreceptor Ly49si1
chr3_+_16753703 57.33 ENSRNOT00000077741

chr13_+_89597138 57.31 ENSRNOT00000004662
apolipoprotein A2
chr6_-_138550576 57.30 ENSRNOT00000075284

chr7_-_54778848 57.29 ENSRNOT00000005399
GLI pathogenesis-related 1
chr1_-_73619356 56.79 ENSRNOT00000074352
leukocyte immunoglobulin like receptor B3
chr4_+_101645731 56.67 ENSRNOT00000087901

chr9_+_8054466 55.41 ENSRNOT00000081513
adhesion G protein-coupled receptor E4
chr7_+_121841855 55.33 ENSRNOT00000024673
GRB2-related adaptor protein 2
chr20_+_3875706 55.16 ENSRNOT00000036900
RT1 class II, locus Ha
chr1_+_227670159 55.03 ENSRNOT00000072077
membrane-spanning 4-domains, subfamily A, member 6C
chr1_-_148119857 54.14 ENSRNOT00000040325
Cytochrome P450, family 2, subfamily c, polypeptide 7-like
chr15_-_29761117 53.77 ENSRNOT00000075194

chr16_-_56900052 53.58 ENSRNOT00000017339
macrophage scavenger receptor 1
chr6_-_138565404 52.83 ENSRNOT00000079420

chr2_+_256964860 52.79 ENSRNOT00000073547
interferon-induced protein 44-like
chrX_-_71168612 52.39 ENSRNOT00000075934
interleukin 2 receptor subunit gamma
chr4_+_154215250 52.35 ENSRNOT00000072465
murinoglobulin 2
chr4_+_154391647 52.10 ENSRNOT00000081488
ENSRNOT00000079192
murinoglobulin 1
chrX_-_79066932 51.87 ENSRNOT00000057460
similar to WASP family 1
chr3_-_16537433 51.84 ENSRNOT00000048523

chr15_+_32614002 51.80 ENSRNOT00000072962

chr15_+_27177900 51.74 ENSRNOT00000039925
toll-like receptor 11
chr13_-_90022269 51.71 ENSRNOT00000035498
lymphocyte antigen 9
chr3_+_19174027 51.47 ENSRNOT00000074445

chr12_-_2438817 50.84 ENSRNOT00000037059
C-C motif chemokine ligand 25
chr15_-_23969011 50.80 ENSRNOT00000014821
GTP cyclohydrolase 1
chr4_+_98337367 50.67 ENSRNOT00000042165

chr5_+_157222636 50.64 ENSRNOT00000022579
phospholipase A2, group IID
chr18_+_55391388 50.60 ENSRNOT00000071612
interferon-inducible GTPase 1-like
chr18_-_6587080 50.57 ENSRNOT00000040815
60S ribosomal protein L39
chr1_+_173252058 50.28 ENSRNOT00000073421
similar to very large inducible GTPase 1 isoform A
chr13_+_90301006 50.17 ENSRNOT00000029315
SLAM family member 6
chr4_-_103258134 50.05 ENSRNOT00000086827

chr3_+_28416954 49.94 ENSRNOT00000043533
kynureninase
chr3_-_17081510 49.81 ENSRNOT00000063862

chr14_+_5928737 49.64 ENSRNOT00000071877
ENSRNOT00000040985
ENSRNOT00000074889
macrophage activation 2 like
chr10_-_110232843 49.50 ENSRNOT00000054934
Cd7 molecule
chr3_-_2853272 49.37 ENSRNOT00000023022
ficolin A
chr7_-_18793289 48.81 ENSRNOT00000036375

chr7_-_29233392 48.78 ENSRNOT00000064241
Spi-C transcription factor
chr14_+_21177237 48.64 ENSRNOT00000004866
immunoglobulin joining chain
chr4_+_99239115 48.60 ENSRNOT00000009515
CD8a molecule
chr4_-_70996395 48.54 ENSRNOT00000021485
Kell blood group, metallo-endopeptidase
chr13_+_92136290 48.53 ENSRNOT00000049819
olfactory receptor 1587
chr16_-_29936307 48.51 ENSRNOT00000088707
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr14_+_10692764 48.38 ENSRNOT00000003012
uncharacterized LOC100910270
chr14_+_10534423 48.20 ENSRNOT00000002983
heparanase
chr5_-_146795866 47.88 ENSRNOT00000065640
toll-like receptor 12
chr3_+_19366370 47.71 ENSRNOT00000086557

chr14_+_22724399 47.62 ENSRNOT00000002724
UDP glucuronosyltransferase 2 family, polypeptide B10
chr2_+_190073815 47.28 ENSRNOT00000015473
S100 calcium binding protein A8
chr4_+_70755795 47.28 ENSRNOT00000043527
similar to Anionic trypsin II precursor (Pretrypsinogen II)
chr1_+_229642412 46.99 ENSRNOT00000017109
leupaxin
chr1_+_148240504 46.79 ENSRNOT00000085373
Cytochrome P450, family 2, subfamily c, polypeptide 7-like
chr1_+_83714347 46.71 ENSRNOT00000085245
cytochrome P450, family 2, subfamily a, polypeptide 1
chr3_+_110855000 46.68 ENSRNOT00000081613
kinetochore scaffold 1
chr1_+_147713892 46.60 ENSRNOT00000092985
ENSRNOT00000054742
ENSRNOT00000074103
cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1
chr16_+_54153054 46.53 ENSRNOT00000090644
ENSRNOT00000014248
fibrinogen-like 1
chr6_-_138679665 46.42 ENSRNOT00000086777

chr8_-_49301125 46.13 ENSRNOT00000091190
CD3e molecule
chr6_-_141321108 46.11 ENSRNOT00000040556

chr10_-_12871965 45.84 ENSRNOT00000004583
predicted gene 8225
chr13_-_91981432 45.83 ENSRNOT00000004637

chr5_-_124403195 45.78 ENSRNOT00000067850
complement C8 alpha chain
chr20_-_29029905 45.26 ENSRNOT00000075682
oncoprotein induced transcript 3
chr18_+_55666027 45.12 ENSRNOT00000045950
similar to CDNA sequence BC023105
chr3_+_19772056 45.06 ENSRNOT00000044455

chr20_+_5184515 44.72 ENSRNOT00000089411
lymphotoxin-beta
chr14_-_71814523 44.70 ENSRNOT00000004094
bone marrow stromal cell antigen 1
chr1_+_213766758 44.57 ENSRNOT00000005645
interferon induced transmembrane protein 1
chr15_-_29548400 44.54 ENSRNOT00000078176

chr15_+_32355565 44.32 ENSRNOT00000072382

chr15_+_32828165 44.11 ENSRNOT00000060253

chr6_-_139747737 44.02 ENSRNOT00000090626

chr15_-_30323833 43.99 ENSRNOT00000071631

chr6_-_140102325 43.94 ENSRNOT00000072238

chr14_+_22375955 43.89 ENSRNOT00000063915
ENSRNOT00000034784
UDP-glucuronosyltransferase 2 family, member 37
chr4_+_109467272 43.88 ENSRNOT00000008212
regenerating family member 3 beta
chr4_+_70689737 43.80 ENSRNOT00000018852
protease, serine, 2
chr7_-_107385528 43.77 ENSRNOT00000093352
transmembrane protein 71
chr3_+_16610086 43.77 ENSRNOT00000046231
rCG64257-like
chr13_+_47572219 43.68 ENSRNOT00000088449
ENSRNOT00000087664
ENSRNOT00000005853
polymeric immunoglobulin receptor
chr3_+_16495748 43.66 ENSRNOT00000045492

chr6_+_128048099 43.44 ENSRNOT00000084685
ENSRNOT00000087017
Ab1-233
chr2_-_173668555 43.36 ENSRNOT00000013452
serpin family I member 2
chr3_-_55587946 43.17 ENSRNOT00000075107
ATP binding cassette subfamily B member 11
chr15_-_45545875 43.00 ENSRNOT00000087678
guanylate cyclase 1 soluble subunit beta 2
chr15_-_28104206 42.95 ENSRNOT00000032536
angiogenin, ribonuclease A family, member 2
chr4_-_167202106 42.81 ENSRNOT00000038581
taste receptor, type 2, member 140
chr4_+_14212925 42.81 ENSRNOT00000076946
platelet glycoprotein 4-like
chr17_-_90149894 42.38 ENSRNOT00000024272
amyloid beta precursor protein binding family B member 1 interacting protein
chr18_+_55463308 42.32 ENSRNOT00000073388
interferon-inducible GTPase 1-like
chr1_-_98521551 41.78 ENSRNOT00000081922
sialic acid binding Ig-like lectin 10
chr8_+_49282460 41.75 ENSRNOT00000021488
CD3d molecule
chr4_+_98371184 41.71 ENSRNOT00000086911

chr4_-_163570803 41.18 ENSRNOT00000082002
ENSRNOT00000078642
killer cell lectin-like receptor family I member 2
chr2_+_104744461 41.15 ENSRNOT00000016083
ENSRNOT00000082627
ceruloplasmin
chr18_+_55466373 41.05 ENSRNOT00000074629
interferon-inducible GTPase 1-like
chr3_-_76187045 41.05 ENSRNOT00000075650
similar to olfactory receptor 73
chr18_+_86299463 40.85 ENSRNOT00000058152
CD226 molecule
chr12_-_51965779 40.70 ENSRNOT00000056733
replication protein A3-like
chr17_+_44760056 40.27 ENSRNOT00000052073
similar to H3 histone, family 3B
chr3_-_118959850 40.25 ENSRNOT00000092750
ATPase phospholipid transporting 8B4 (putative)
chr15_-_24199341 40.24 ENSRNOT00000015553
DLG associated protein 5
chr6_-_138632159 39.97 ENSRNOT00000082921
ENSRNOT00000040702
immunoglobulin heavy constant mu
chr13_+_53351717 39.96 ENSRNOT00000012038
kinesin family member 14
chr3_+_19274273 39.95 ENSRNOT00000040102

chr3_-_44177689 39.94 ENSRNOT00000006387
cytohesin 1 interacting protein
chr2_+_186776644 39.85 ENSRNOT00000046778
Fc receptor-like 3
chr4_+_65110746 39.74 ENSRNOT00000017675
aldo-keto reductase family 1, member D1
chr17_+_43633675 39.72 ENSRNOT00000072119
histone H3.2-like
chr14_-_19191863 39.71 ENSRNOT00000003921
albumin
chr9_+_95256627 39.69 ENSRNOT00000025291
UDP glucuronosyltransferase family 1 member A5
chr17_-_43776460 39.64 ENSRNOT00000089055
histone cluster 2, H3c2
chr10_-_90415070 39.63 ENSRNOT00000055179
integrin subunit alpha 2b
chr1_-_258877045 39.60 ENSRNOT00000071633
cytochrome P450, family 2, subfamily c, polypeptide 13
chr1_+_189328246 39.44 ENSRNOT00000084260
acyl-CoA synthetase medium-chain family member 1
chr9_+_67763897 39.36 ENSRNOT00000071226
inducible T-cell co-stimulator
chr6_-_140572023 39.36 ENSRNOT00000072338

chr6_-_143065639 39.34 ENSRNOT00000070923

chr14_+_22517774 39.33 ENSRNOT00000047655
UDP-glucuronosyltransferase 2 family, member 37
chr9_+_41006800 39.26 ENSRNOT00000079413
ENSRNOT00000034214
protease, serine, 39
chr1_+_223214132 39.06 ENSRNOT00000066559

chr20_+_4020317 38.99 ENSRNOT00000000526
RT1 class II, locus DOb
chr6_-_138662365 38.89 ENSRNOT00000066209
ENSRNOT00000084892
immunoglobulin heavy constant mu
chr15_+_31642169 38.87 ENSRNOT00000072362

chr15_-_29246222 38.66 ENSRNOT00000081806

chr4_+_14151343 38.64 ENSRNOT00000061687
ENSRNOT00000076573
ENSRNOT00000077219
ENSRNOT00000008319
CD36 molecule
chr12_+_30198822 38.62 ENSRNOT00000041645
glucuronidase, beta
chr15_-_34479741 38.53 ENSRNOT00000027759
receptor-interacting serine-threonine kinase 3
chr6_-_139102378 38.34 ENSRNOT00000086423

chr13_-_36101411 38.34 ENSRNOT00000074471
transmembrane protein 37
chr4_-_157263890 38.31 ENSRNOT00000065416
protein tyrosine phosphatase, non-receptor type 6
chr12_-_2826378 38.18 ENSRNOT00000061749
C-type lectin domain family 4 member M
chr1_-_16687817 38.03 ENSRNOT00000091376
ENSRNOT00000081620
MYB proto-oncogene, transcription factor
chr1_-_216828581 38.02 ENSRNOT00000066943
ENSRNOT00000088856
tumor necrosis factor receptor superfamily, member 26

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxj3_Tbl1xr1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
61.5 184.4 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
28.5 170.7 GO:0072564 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
27.8 222.5 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
26.0 78.0 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
25.8 103.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
25.2 75.6 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
23.0 23.0 GO:0060101 negative regulation of phagocytosis, engulfment(GO:0060101)
22.4 67.2 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
22.1 44.3 GO:0034125 negative regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034125)
21.8 43.6 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
21.4 64.2 GO:1990869 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
21.2 148.7 GO:0070269 pyroptosis(GO:0070269)
21.2 21.2 GO:0045608 negative regulation of auditory receptor cell differentiation(GO:0045608)
20.7 62.1 GO:0071733 regulation of primitive erythrocyte differentiation(GO:0010725) transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
20.2 40.3 GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
19.8 79.0 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
19.7 78.9 GO:0070543 response to linoleic acid(GO:0070543)
19.2 57.7 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
19.2 57.5 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
19.1 171.9 GO:0052697 xenobiotic glucuronidation(GO:0052697)
18.9 510.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
18.8 75.4 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
18.7 56.0 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
18.5 55.6 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
18.3 54.9 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
17.6 70.5 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
17.3 52.0 GO:0010915 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
17.3 189.9 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
17.1 68.2 GO:0002344 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
17.0 68.0 GO:1903576 response to L-arginine(GO:1903576)
16.9 50.8 GO:0014916 regulation of lung blood pressure(GO:0014916)
16.8 50.3 GO:2000449 regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449)
16.5 49.5 GO:0070946 neutrophil mediated killing of gram-positive bacterium(GO:0070946)
16.5 49.4 GO:0002215 defense response to nematode(GO:0002215)
16.4 32.9 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
16.3 65.3 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
16.1 96.5 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
16.1 48.2 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
15.7 188.3 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
15.4 15.4 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
15.1 30.3 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
14.8 44.3 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
14.7 73.7 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
14.5 29.0 GO:0002727 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
14.5 57.9 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
14.4 43.3 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
14.4 43.2 GO:0021698 cerebellar cortex structural organization(GO:0021698)
14.3 14.3 GO:1903923 protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
14.2 42.7 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
14.1 70.7 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
14.1 98.8 GO:0030101 natural killer cell activation(GO:0030101)
14.0 28.0 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
13.9 27.8 GO:1904580 regulation of intracellular mRNA localization(GO:1904580)
13.8 41.5 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
13.8 68.8 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
13.6 40.9 GO:2000458 astrocyte chemotaxis(GO:0035700) regulation of astrocyte chemotaxis(GO:2000458)
13.5 13.5 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
13.5 161.9 GO:0032740 positive regulation of interleukin-17 production(GO:0032740)
13.5 67.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
13.4 66.9 GO:0006548 histidine catabolic process(GO:0006548)
13.3 26.6 GO:0032701 negative regulation of interleukin-18 production(GO:0032701)
13.2 52.9 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
13.0 52.0 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
12.8 25.7 GO:2000422 regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
12.7 38.0 GO:2000845 positive regulation of testosterone secretion(GO:2000845)
12.7 88.6 GO:0051572 negative regulation of histone H3-K4 methylation(GO:0051572)
12.5 25.0 GO:0002503 MHC class II protein complex assembly(GO:0002399) peptide antigen assembly with MHC class II protein complex(GO:0002503)
12.4 37.2 GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
12.4 136.0 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
12.0 24.1 GO:0070228 regulation of lymphocyte apoptotic process(GO:0070228)
12.0 36.1 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
12.0 48.0 GO:0051132 NK T cell activation(GO:0051132)
12.0 23.9 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
12.0 59.8 GO:0002457 T cell antigen processing and presentation(GO:0002457)
11.8 47.2 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
11.7 35.1 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
11.7 46.7 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
11.6 23.3 GO:0070947 neutrophil mediated killing of fungus(GO:0070947)
11.4 34.2 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
11.4 11.4 GO:0070268 cornification(GO:0070268)
11.3 56.6 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
11.3 22.6 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
11.3 33.9 GO:1901726 negative regulation of histone deacetylase activity(GO:1901726)
11.2 67.3 GO:0061737 leukotriene signaling pathway(GO:0061737)
11.1 22.2 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
11.1 22.1 GO:0070839 divalent metal ion export(GO:0070839)
11.0 11.0 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
11.0 33.0 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
10.9 65.2 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
10.8 75.5 GO:0015722 canalicular bile acid transport(GO:0015722)
10.8 118.6 GO:0010818 T cell chemotaxis(GO:0010818)
10.8 32.3 GO:0002337 B-1a B cell differentiation(GO:0002337)
10.7 21.3 GO:0002579 positive regulation of antigen processing and presentation(GO:0002579)
10.6 31.7 GO:0071461 cellular response to redox state(GO:0071461)
10.5 284.3 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
10.5 10.5 GO:0045402 interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
10.5 31.4 GO:1904444 regulation of establishment of Sertoli cell barrier(GO:1904444)
10.3 41.3 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
10.2 20.3 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
10.1 60.6 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
10.0 20.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
9.9 39.7 GO:0001907 killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
9.9 88.8 GO:2000484 positive regulation of interleukin-8 secretion(GO:2000484)
9.8 29.4 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455)
9.7 291.6 GO:0006958 complement activation, classical pathway(GO:0006958)
9.7 38.7 GO:0034240 negative regulation of macrophage fusion(GO:0034240)
9.6 19.2 GO:0046874 quinolinate metabolic process(GO:0046874)
9.6 38.4 GO:0009992 cellular water homeostasis(GO:0009992)
9.6 47.9 GO:0015755 fructose transport(GO:0015755)
9.6 296.5 GO:0035458 cellular response to interferon-beta(GO:0035458)
9.5 19.1 GO:0010034 response to acetate(GO:0010034)
9.5 57.2 GO:0060267 positive regulation of respiratory burst(GO:0060267)
9.5 76.2 GO:0010216 maintenance of DNA methylation(GO:0010216)
9.5 66.5 GO:0045091 single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
9.5 28.4 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
9.4 47.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
9.4 112.5 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
9.4 28.1 GO:0046061 dATP catabolic process(GO:0046061)
9.3 130.5 GO:0006956 complement activation(GO:0006956)
9.3 18.5 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)
9.3 46.3 GO:0010037 response to carbon dioxide(GO:0010037)
9.2 27.6 GO:0019677 NAD catabolic process(GO:0019677)
9.2 91.8 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
9.2 55.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
9.1 27.4 GO:0046864 isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
9.1 9.1 GO:0042253 granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
9.0 9.0 GO:0060235 lens induction in camera-type eye(GO:0060235)
9.0 135.4 GO:0034501 protein localization to kinetochore(GO:0034501)
8.9 62.5 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
8.9 8.9 GO:0072566 chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
8.9 62.2 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
8.9 124.1 GO:0042832 defense response to protozoan(GO:0042832)
8.8 70.3 GO:0002360 T cell lineage commitment(GO:0002360)
8.7 8.7 GO:0046618 drug export(GO:0046618)
8.7 69.6 GO:0015679 plasma membrane copper ion transport(GO:0015679)
8.6 25.8 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
8.6 42.8 GO:0009115 xanthine catabolic process(GO:0009115)
8.5 42.7 GO:0006569 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
8.5 34.0 GO:1902741 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
8.5 17.0 GO:1902226 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
8.5 25.4 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
8.4 50.4 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
8.4 25.2 GO:0019265 glycine biosynthetic process, by transamination of glyoxylate(GO:0019265)
8.4 16.7 GO:0001810 regulation of type I hypersensitivity(GO:0001810) type I hypersensitivity(GO:0016068)
8.3 16.6 GO:0032621 interleukin-18 production(GO:0032621)
8.3 91.2 GO:0002517 T cell tolerance induction(GO:0002517)
8.3 99.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
8.3 33.1 GO:1904975 response to bleomycin(GO:1904975)
8.3 41.4 GO:0033625 positive regulation of integrin activation(GO:0033625)
8.3 33.0 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
8.2 73.8 GO:0045059 positive thymic T cell selection(GO:0045059)
8.2 40.9 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
8.1 105.9 GO:0035634 response to stilbenoid(GO:0035634)
8.1 24.4 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
8.1 40.6 GO:2000108 positive regulation of leukocyte apoptotic process(GO:2000108)
8.1 24.3 GO:0045416 positive regulation of interleukin-8 biosynthetic process(GO:0045416)
8.1 8.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
8.0 24.1 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
8.0 16.0 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
7.9 102.6 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
7.8 31.1 GO:0006272 leading strand elongation(GO:0006272)
7.8 31.0 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
7.8 23.3 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
7.7 30.9 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
7.6 38.2 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
7.6 60.8 GO:0000050 urea cycle(GO:0000050)
7.5 15.1 GO:0097278 complement-dependent cytotoxicity(GO:0097278)
7.5 30.1 GO:0032827 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
7.5 7.5 GO:2000630 positive regulation of miRNA metabolic process(GO:2000630)
7.5 67.7 GO:0022614 membrane to membrane docking(GO:0022614)
7.5 60.1 GO:0001865 NK T cell differentiation(GO:0001865)
7.5 22.5 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
7.5 112.5 GO:0015671 oxygen transport(GO:0015671)
7.5 7.5 GO:1904170 regulation of bleb assembly(GO:1904170)
7.5 29.9 GO:0002315 marginal zone B cell differentiation(GO:0002315)
7.4 74.5 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
7.4 29.8 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
7.4 51.8 GO:0016584 nucleosome positioning(GO:0016584)
7.4 7.4 GO:0002780 antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780)
7.4 66.5 GO:0006968 cellular defense response(GO:0006968)
7.4 14.8 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
7.3 29.2 GO:0097527 necroptotic signaling pathway(GO:0097527)
7.3 65.3 GO:0035456 response to interferon-beta(GO:0035456)
7.2 7.2 GO:0042509 regulation of tyrosine phosphorylation of STAT protein(GO:0042509) positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
7.2 28.8 GO:0019371 cyclooxygenase pathway(GO:0019371)
7.2 21.6 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
7.2 28.7 GO:0001834 trophectodermal cell proliferation(GO:0001834)
7.1 14.3 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
7.1 21.4 GO:0002281 macrophage activation involved in immune response(GO:0002281)
7.1 21.3 GO:0006116 NADH oxidation(GO:0006116)
7.1 28.4 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168)
7.1 28.4 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
7.1 99.0 GO:0006067 ethanol metabolic process(GO:0006067)
7.0 28.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
7.0 21.1 GO:0014739 positive regulation of muscle hyperplasia(GO:0014739)
6.9 20.8 GO:0006547 histidine metabolic process(GO:0006547)
6.9 48.5 GO:0032074 negative regulation of nuclease activity(GO:0032074)
6.9 13.9 GO:1901523 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
6.9 20.7 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
6.9 20.7 GO:0030576 Cajal body organization(GO:0030576)
6.9 27.6 GO:0034421 post-translational protein acetylation(GO:0034421)
6.9 13.8 GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
6.9 20.6 GO:1903173 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
6.9 6.9 GO:0071226 cellular response to molecule of fungal origin(GO:0071226)
6.9 20.6 GO:0034769 basement membrane disassembly(GO:0034769)
6.8 13.6 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
6.8 61.0 GO:0043368 positive T cell selection(GO:0043368)
6.8 20.3 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
6.7 13.4 GO:0046967 cytosol to ER transport(GO:0046967) peptide antigen transport(GO:0046968)
6.7 6.7 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716)
6.7 13.3 GO:0071259 cellular response to magnetism(GO:0071259)
6.7 40.0 GO:0033623 regulation of integrin activation(GO:0033623)
6.7 26.6 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
6.6 33.0 GO:0010032 meiotic chromosome condensation(GO:0010032)
6.6 19.8 GO:0051977 lysophospholipid transport(GO:0051977)
6.5 19.6 GO:1990743 protein sialylation(GO:1990743)
6.5 13.1 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
6.5 6.5 GO:0061470 T follicular helper cell differentiation(GO:0061470)
6.5 25.9 GO:0045903 positive regulation of translational fidelity(GO:0045903)
6.5 25.9 GO:0071608 macrophage inflammatory protein-1 alpha production(GO:0071608) regulation of macrophage inflammatory protein 1 alpha production(GO:0071640)
6.4 25.8 GO:0016554 cytidine to uridine editing(GO:0016554)
6.4 77.1 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
6.4 63.7 GO:0006570 tyrosine metabolic process(GO:0006570)
6.2 18.6 GO:1903860 negative regulation of dendrite extension(GO:1903860)
6.1 6.1 GO:0002644 negative regulation of tolerance induction(GO:0002644)
6.1 18.4 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
6.1 18.4 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
6.1 18.4 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
6.1 220.2 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
6.1 30.5 GO:0010360 negative regulation of anion channel activity(GO:0010360)
6.0 48.4 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
6.0 42.1 GO:0042730 fibrinolysis(GO:0042730)
6.0 17.9 GO:0042222 interleukin-1 biosynthetic process(GO:0042222)
6.0 6.0 GO:0009624 response to nematode(GO:0009624)
5.9 29.7 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
5.9 29.6 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
5.9 5.9 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
5.9 23.6 GO:0060155 platelet dense granule organization(GO:0060155)
5.9 35.4 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
5.9 64.4 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
5.8 23.4 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
5.7 28.6 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
5.7 22.9 GO:0002507 tolerance induction(GO:0002507)
5.7 22.7 GO:0046645 positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
5.7 22.7 GO:0001574 ganglioside biosynthetic process(GO:0001574)
5.6 33.8 GO:0030916 otic vesicle formation(GO:0030916)
5.6 5.6 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
5.6 11.2 GO:0003162 atrioventricular node development(GO:0003162)
5.6 22.4 GO:0097681 double-strand break repair via alternative nonhomologous end joining(GO:0097681)
5.6 11.1 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
5.5 27.7 GO:0089700 protein kinase D signaling(GO:0089700)
5.5 16.6 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
5.5 22.1 GO:0009441 glycolate metabolic process(GO:0009441)
5.5 82.8 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
5.5 27.6 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
5.5 66.1 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
5.5 22.0 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
5.5 120.8 GO:0030574 collagen catabolic process(GO:0030574)
5.5 11.0 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
5.5 103.9 GO:0001833 inner cell mass cell proliferation(GO:0001833)
5.4 10.9 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
5.4 70.3 GO:0002551 mast cell chemotaxis(GO:0002551)
5.4 10.8 GO:0060003 copper ion export(GO:0060003)
5.4 26.9 GO:0050798 activated T cell proliferation(GO:0050798)
5.4 10.8 GO:0042360 vitamin E metabolic process(GO:0042360)
5.4 21.5 GO:0061113 pancreas morphogenesis(GO:0061113)
5.4 48.2 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
5.4 10.7 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
5.3 16.0 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
5.3 21.4 GO:1903334 positive regulation of protein folding(GO:1903334)
5.3 96.0 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
5.3 16.0 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
5.3 26.5 GO:1903925 response to bisphenol A(GO:1903925)
5.3 42.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
5.3 47.5 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
5.3 15.8 GO:0016267 O-glycan processing, core 1(GO:0016267)
5.3 10.5 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
5.2 15.6 GO:0090135 actin filament branching(GO:0090135)
5.2 15.6 GO:1901423 response to benzene(GO:1901423)
5.2 20.8 GO:1902093 positive regulation of sperm motility(GO:1902093)
5.2 5.2 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
5.1 36.0 GO:0051026 chiasma assembly(GO:0051026)
5.1 30.8 GO:0045329 carnitine biosynthetic process(GO:0045329)
5.1 40.8 GO:0048535 lymph node development(GO:0048535)
5.1 5.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
5.1 111.6 GO:0006855 drug transmembrane transport(GO:0006855)
5.1 25.3 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
5.1 10.1 GO:0060167 regulation of adenosine receptor signaling pathway(GO:0060167)
5.0 5.0 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
5.0 15.0 GO:0030221 basophil differentiation(GO:0030221)
5.0 49.9 GO:0006265 DNA topological change(GO:0006265)
5.0 5.0 GO:0060847 endothelial cell fate specification(GO:0060847)
5.0 49.7 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
5.0 14.9 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
4.9 14.8 GO:0097350 neutrophil clearance(GO:0097350)
4.9 14.8 GO:0060066 oviduct development(GO:0060066)
4.9 44.5 GO:0003360 brainstem development(GO:0003360)
4.9 4.9 GO:0010873 positive regulation of cholesterol esterification(GO:0010873)
4.9 24.5 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
4.9 9.8 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
4.9 9.8 GO:0016098 monoterpenoid metabolic process(GO:0016098)
4.9 24.4 GO:0050917 sensory perception of umami taste(GO:0050917)
4.8 24.2 GO:0006177 GMP biosynthetic process(GO:0006177)
4.8 14.5 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
4.8 53.1 GO:0002227 innate immune response in mucosa(GO:0002227)
4.8 14.3 GO:0019303 D-ribose catabolic process(GO:0019303)
4.8 28.6 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
4.8 19.1 GO:0048252 lauric acid metabolic process(GO:0048252)
4.8 14.3 GO:0009227 nucleotide-sugar catabolic process(GO:0009227)
4.8 4.8 GO:0070541 response to platinum ion(GO:0070541)
4.8 14.3 GO:0007403 glial cell fate determination(GO:0007403)
4.7 9.5 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
4.7 4.7 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
4.7 9.5 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
4.7 18.9 GO:0006685 sphingomyelin catabolic process(GO:0006685)
4.7 14.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
4.7 4.7 GO:0000966 RNA 5'-end processing(GO:0000966)
4.7 9.4 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
4.7 28.2 GO:0090267 positive regulation of spindle checkpoint(GO:0090232) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
4.7 18.7 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
4.7 9.4 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
4.7 14.0 GO:0018992 germ-line sex determination(GO:0018992)
4.6 9.2 GO:1902569 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
4.6 9.1 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
4.5 40.9 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
4.5 22.7 GO:0051594 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
4.5 13.6 GO:0090487 toxin catabolic process(GO:0009407) mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) secondary metabolite catabolic process(GO:0090487) organic heteropentacyclic compound catabolic process(GO:1901377)
4.5 22.5 GO:0070170 regulation of tooth mineralization(GO:0070170)
4.5 13.5 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
4.4 13.2 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
4.4 119.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
4.4 13.2 GO:0042126 nitrate metabolic process(GO:0042126)
4.4 4.4 GO:0006014 D-ribose metabolic process(GO:0006014)
4.4 26.4 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
4.4 8.8 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
4.4 26.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
4.4 17.5 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
4.4 4.4 GO:0048102 autophagic cell death(GO:0048102)
4.3 13.0 GO:0006045 N-acetylglucosamine biosynthetic process(GO:0006045) N-acetylneuraminate biosynthetic process(GO:0046380)
4.3 12.9 GO:0019660 fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
4.3 4.3 GO:0035740 CD8-positive, alpha-beta T cell proliferation(GO:0035740)
4.2 17.0 GO:0019585 uronic acid metabolic process(GO:0006063) glucuronate metabolic process(GO:0019585)
4.2 29.7 GO:0033004 negative regulation of mast cell activation(GO:0033004)
4.2 21.2 GO:0035376 sterol import(GO:0035376) cholesterol import(GO:0070508)
4.2 25.4 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
4.2 4.2 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
4.2 12.6 GO:0072697 protein localization to cell cortex(GO:0072697)
4.2 21.0 GO:0010587 miRNA catabolic process(GO:0010587)
4.2 4.2 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
4.2 16.8 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
4.2 130.0 GO:0006953 acute-phase response(GO:0006953)
4.2 8.3 GO:0045357 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357)
4.2 33.3 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
4.2 8.3 GO:0043316 cytotoxic T cell degranulation(GO:0043316)
4.1 4.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
4.1 8.3 GO:0002326 B cell lineage commitment(GO:0002326)
4.1 32.9 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
4.1 20.5 GO:0002827 positive regulation of T-helper 1 type immune response(GO:0002827)
4.1 4.1 GO:0009436 glyoxylate catabolic process(GO:0009436)
4.1 12.2 GO:0046015 regulation of transcription by glucose(GO:0046015)
4.0 72.8 GO:0071803 positive regulation of podosome assembly(GO:0071803)
4.0 12.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
4.0 12.1 GO:0045414 interleukin-8 biosynthetic process(GO:0042228) regulation of interleukin-8 biosynthetic process(GO:0045414)
4.0 12.0 GO:0016240 autophagosome docking(GO:0016240)
4.0 15.9 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
4.0 4.0 GO:1905204 negative regulation of connective tissue replacement(GO:1905204)
4.0 8.0 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of glycogen catabolic process(GO:0045819) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
4.0 11.9 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
3.9 15.8 GO:0046641 positive regulation of alpha-beta T cell proliferation(GO:0046641)
3.9 7.9 GO:1904354 negative regulation of telomere capping(GO:1904354)
3.9 19.7 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
3.9 11.8 GO:0048749 compound eye development(GO:0048749)
3.9 23.4 GO:0000255 allantoin metabolic process(GO:0000255)
3.9 3.9 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
3.9 7.8 GO:0002339 B cell selection(GO:0002339)
3.9 34.9 GO:0001771 immunological synapse formation(GO:0001771)
3.9 3.9 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
3.9 3.9 GO:0007060 male meiosis chromosome segregation(GO:0007060)
3.9 7.7 GO:0042668 auditory receptor cell fate determination(GO:0042668)
3.9 11.6 GO:1901535 protection of DNA demethylation of female pronucleus(GO:0044726) regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
3.8 11.5 GO:0090166 Golgi disassembly(GO:0090166)
3.8 3.8 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
3.8 15.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
3.8 26.6 GO:0007096 regulation of exit from mitosis(GO:0007096)
3.8 11.3 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
3.8 3.8 GO:0046687 response to chromate(GO:0046687)
3.8 15.0 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
3.7 11.2 GO:0090081 regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
3.7 48.4 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
3.7 14.9 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
3.7 3.7 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
3.7 107.9 GO:0000028 ribosomal small subunit assembly(GO:0000028)
3.7 11.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
3.7 3.7 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
3.7 70.0 GO:0032814 regulation of natural killer cell activation(GO:0032814)
3.7 36.8 GO:0002467 germinal center formation(GO:0002467)
3.7 36.6 GO:0007076 mitotic chromosome condensation(GO:0007076)
3.7 47.5 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
3.6 10.9 GO:0071031 nuclear mRNA surveillance of mRNA 3'-end processing(GO:0071031) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038) nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription(GO:0071049)
3.6 10.9 GO:0030505 inorganic diphosphate transport(GO:0030505)
3.6 10.9 GO:0006011 UDP-glucose metabolic process(GO:0006011)
3.6 14.4 GO:0002407 dendritic cell chemotaxis(GO:0002407)
3.6 10.8 GO:0006642 triglyceride mobilization(GO:0006642)
3.6 10.8 GO:0009609 response to symbiotic bacterium(GO:0009609)
3.6 21.6 GO:0070544 histone H3-K36 demethylation(GO:0070544)
3.6 25.2 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
3.6 35.9 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
3.6 35.9 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
3.6 10.7 GO:0019230 proprioception(GO:0019230)
3.5 7.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
3.5 14.1 GO:0019372 lipoxygenase pathway(GO:0019372)
3.5 17.6 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
3.5 14.0 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
3.5 3.5 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
3.5 20.8 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
3.5 10.4 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
3.5 17.3 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
3.5 13.8 GO:2000354 regulation of ovarian follicle development(GO:2000354)
3.4 3.4 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
3.4 10.2 GO:0046060 dATP metabolic process(GO:0046060)
3.4 34.1 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
3.4 17.0 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
3.4 6.8 GO:0007356 thorax and anterior abdomen determination(GO:0007356)
3.4 10.2 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
3.4 747.5 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
3.4 6.8 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
3.4 10.2 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
3.4 50.8 GO:0006691 leukotriene metabolic process(GO:0006691)
3.4 6.7 GO:0043504 mitochondrial DNA repair(GO:0043504)
3.4 23.6 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
3.3 26.6 GO:0042130 negative regulation of T cell proliferation(GO:0042130)
3.3 6.7 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
3.3 49.9 GO:0050869 negative regulation of B cell activation(GO:0050869)
3.3 13.3 GO:0072757 cellular response to camptothecin(GO:0072757)
3.3 26.5 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
3.3 9.9 GO:0061010 gall bladder development(GO:0061010)
3.3 16.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
3.3 3.3 GO:1901630 negative regulation of presynaptic membrane organization(GO:1901630)
3.3 3.3 GO:0034135 regulation of toll-like receptor 2 signaling pathway(GO:0034135) positive regulation of toll-like receptor 2 signaling pathway(GO:0034137) response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
3.3 6.5 GO:0042197 chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
3.3 9.8 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
3.3 3.3 GO:1990478 response to ultrasound(GO:1990478)
3.3 13.0 GO:0010266 response to vitamin B1(GO:0010266)
3.3 6.5 GO:2001267 regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001267) positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
3.2 16.2 GO:0075525 viral translational termination-reinitiation(GO:0075525)
3.2 9.7 GO:0019474 lysine catabolic process(GO:0006554) L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
3.2 12.9 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
3.2 16.1 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
3.2 22.4 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
3.2 3.2 GO:0032645 granulocyte macrophage colony-stimulating factor production(GO:0032604) regulation of granulocyte macrophage colony-stimulating factor production(GO:0032645)
3.2 15.9 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
3.2 19.0 GO:1900016 negative regulation of cytokine production involved in inflammatory response(GO:1900016)
3.2 9.5 GO:0021569 rhombomere 3 development(GO:0021569)
3.2 15.8 GO:0035627 ceramide transport(GO:0035627)
3.2 9.5 GO:0060383 positive regulation of DNA strand elongation(GO:0060383)
3.1 3.1 GO:1903936 cellular response to sodium arsenite(GO:1903936)
3.1 15.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
3.1 46.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
3.1 15.4 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
3.1 3.1 GO:0010958 regulation of amino acid import(GO:0010958)
3.1 18.4 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
3.1 3.1 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
3.1 3.1 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
3.0 6.1 GO:0048850 hypophysis morphogenesis(GO:0048850)
3.0 3.0 GO:0046671 negative regulation of retinal cell programmed cell death(GO:0046671)
3.0 45.3 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
3.0 9.0 GO:0006214 thymidine catabolic process(GO:0006214) pyrimidine deoxyribonucleoside catabolic process(GO:0046127)
3.0 12.0 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
3.0 6.0 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
3.0 5.9 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
3.0 11.9 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
3.0 8.9 GO:0021524 visceral motor neuron differentiation(GO:0021524)
3.0 3.0 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
3.0 14.8 GO:0014901 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
2.9 8.8 GO:0016102 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
2.9 5.9 GO:0071104 response to interleukin-9(GO:0071104)
2.9 17.7 GO:0001878 response to yeast(GO:0001878)
2.9 8.8 GO:0046351 disaccharide biosynthetic process(GO:0046351)
2.9 8.8 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
2.9 8.8 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
2.9 26.4 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
2.9 5.8 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
2.9 8.7 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
2.9 14.5 GO:0090160 Golgi to lysosome transport(GO:0090160)
2.9 28.9 GO:0070989 oxidative demethylation(GO:0070989)
2.9 11.5 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
2.9 8.6 GO:2000667 interleukin-5 secretion(GO:0072603) interleukin-13 secretion(GO:0072611) regulation of interleukin-5 secretion(GO:2000662) positive regulation of interleukin-5 secretion(GO:2000664) regulation of interleukin-13 secretion(GO:2000665) positive regulation of interleukin-13 secretion(GO:2000667)
2.9 11.5 GO:0001579 medium-chain fatty acid transport(GO:0001579)
2.9 11.5 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
2.9 31.6 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
2.9 20.0 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
2.8 5.7 GO:0072717 cellular response to actinomycin D(GO:0072717)
2.8 5.7 GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516)
2.8 8.5 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
2.8 8.5 GO:0033575 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
2.8 215.0 GO:0045814 negative regulation of gene expression, epigenetic(GO:0045814)
2.8 2.8 GO:1904868 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
2.8 8.4 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
2.8 16.9 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
2.8 22.5 GO:0010668 ectodermal cell differentiation(GO:0010668)
2.8 5.6 GO:0033123 positive regulation of purine nucleotide catabolic process(GO:0033123)
2.8 8.4 GO:0036018 cellular response to erythropoietin(GO:0036018)
2.8 2.8 GO:1990791 dorsal root ganglion development(GO:1990791)
2.8 2.8 GO:0045351 type I interferon biosynthetic process(GO:0045351)
2.7 13.7 GO:0048478 replication fork protection(GO:0048478)
2.7 19.1 GO:2000401 regulation of lymphocyte migration(GO:2000401)
2.7 35.5 GO:0061436 establishment of skin barrier(GO:0061436)
2.7 16.4 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
2.7 5.4 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
2.7 5.4 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
2.7 8.1 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
2.7 8.1 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
2.7 5.4 GO:0000212 meiotic spindle organization(GO:0000212)
2.7 8.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
2.7 27.0 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
2.7 5.4 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
2.7 2.7 GO:0060460 left lung morphogenesis(GO:0060460)
2.7 29.6 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
2.7 8.1 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
2.7 10.7 GO:0001682 tRNA 5'-leader removal(GO:0001682)
2.7 13.4 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
2.7 18.7 GO:0043686 co-translational protein modification(GO:0043686)
2.7 18.6 GO:0021979 hypothalamus cell differentiation(GO:0021979)
2.6 7.9 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
2.6 13.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
2.6 2.6 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
2.6 65.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
2.6 7.9 GO:1904798 positive regulation of core promoter binding(GO:1904798)
2.6 7.8 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
2.6 15.7 GO:0043249 erythrocyte maturation(GO:0043249)
2.6 7.8 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
2.6 13.0 GO:0006741 NADP biosynthetic process(GO:0006741)
2.6 15.5 GO:0032674 regulation of interleukin-5 production(GO:0032674)
2.6 7.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
2.5 5.1 GO:0015684 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
2.5 5.1 GO:0035772 interleukin-13-mediated signaling pathway(GO:0035772)
2.5 2.5 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
2.5 2.5 GO:0046487 glyoxylate metabolic process(GO:0046487)
2.5 7.6 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
2.5 45.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095) G2 DNA damage checkpoint(GO:0031572)
2.5 5.1 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
2.5 10.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
2.5 7.6 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
2.5 17.6 GO:0042866 pyruvate biosynthetic process(GO:0042866)
2.5 15.0 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
2.5 7.5 GO:1901094 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
2.5 2.5 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
2.5 10.0 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
2.5 12.5 GO:0015838 amino-acid betaine transport(GO:0015838)
2.5 10.0 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
2.5 9.9 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
2.5 14.9 GO:0007021 tubulin complex assembly(GO:0007021)
2.5 5.0 GO:0031125 rRNA 3'-end processing(GO:0031125)
2.5 12.4 GO:0071500 cellular response to nitrosative stress(GO:0071500)
2.5 5.0 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
2.5 7.4 GO:0080144 amino acid homeostasis(GO:0080144)
2.5 12.3 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
2.5 51.8 GO:0071346 cellular response to interferon-gamma(GO:0071346)
2.5 24.7 GO:0002283 neutrophil activation involved in immune response(GO:0002283)
2.5 2.5 GO:0061511 centriole elongation(GO:0061511)
2.4 12.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
2.4 41.6 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
2.4 9.8 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
2.4 65.8 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
2.4 2.4 GO:0030263 apoptotic chromosome condensation(GO:0030263)
2.4 24.3 GO:0042178 xenobiotic catabolic process(GO:0042178)
2.4 26.7 GO:0035562 negative regulation of chromatin binding(GO:0035562)
2.4 12.1 GO:0001835 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
2.4 29.0 GO:0046415 urate metabolic process(GO:0046415)
2.4 7.2 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
2.4 24.0 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
2.4 4.8 GO:0002191 cap-dependent translational initiation(GO:0002191)
2.4 9.6 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
2.4 2.4 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086)
2.4 26.1 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
2.4 4.7 GO:0043587 tongue morphogenesis(GO:0043587)
2.3 2.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
2.3 91.3 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
2.3 32.7 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
2.3 7.0 GO:0006206 pyrimidine nucleobase metabolic process(GO:0006206)
2.3 11.7 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
2.3 14.0 GO:0000733 DNA strand renaturation(GO:0000733)
2.3 18.6 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
2.3 2.3 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
2.3 23.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
2.3 9.2 GO:0060700 regulation of ribonuclease activity(GO:0060700)
2.3 13.8 GO:0043304 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
2.3 4.6 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
2.3 11.5 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
2.3 4.6 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
2.3 13.7 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
2.3 20.5 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
2.3 11.4 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
2.3 6.8 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
2.3 9.0 GO:0032025 response to cobalt ion(GO:0032025)
2.2 22.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
2.2 11.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
2.2 26.7 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
2.2 4.4 GO:0016321 female meiosis chromosome segregation(GO:0016321)
2.2 8.8 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
2.2 4.4 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
2.2 17.5 GO:0010815 bradykinin catabolic process(GO:0010815)
2.2 6.5 GO:0001832 blastocyst growth(GO:0001832)
2.2 62.9 GO:0002260 lymphocyte homeostasis(GO:0002260)
2.2 4.3 GO:0035964 COPI-coated vesicle budding(GO:0035964)
2.2 4.3 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
2.1 2757.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
2.1 6.4 GO:0021747 cochlear nucleus development(GO:0021747)
2.1 62.1 GO:0006284 base-excision repair(GO:0006284)
2.1 74.9 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
2.1 10.6 GO:0060056 mammary gland involution(GO:0060056)
2.1 10.6 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
2.1 10.6 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
2.1 8.4 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
2.1 2.1 GO:0031999 negative regulation of fatty acid beta-oxidation(GO:0031999)
2.1 4.2 GO:2000359 regulation of binding of sperm to zona pellucida(GO:2000359) negative regulation of binding of sperm to zona pellucida(GO:2000360)
2.1 16.8 GO:0006703 estrogen biosynthetic process(GO:0006703)
2.1 4.2 GO:0035600 tRNA methylthiolation(GO:0035600)
2.1 8.4 GO:0051095 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
2.1 16.6 GO:0046473 phosphatidic acid metabolic process(GO:0046473)
2.1 4.2 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
2.1 39.4 GO:0009225 nucleotide-sugar metabolic process(GO:0009225)
2.1 60.2 GO:0051028 mRNA transport(GO:0051028)
2.1 60.1 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
2.1 6.2 GO:0097327 response to antineoplastic agent(GO:0097327)
2.1 16.5 GO:0051299 centrosome separation(GO:0051299)
2.1 6.2 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
2.1 4.1 GO:0002380 immunoglobulin secretion involved in immune response(GO:0002380)
2.1 6.2 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
2.0 6.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
2.0 4.0 GO:0043032 positive regulation of macrophage activation(GO:0043032)
2.0 60.3 GO:0051607 defense response to virus(GO:0051607)
2.0 6.0 GO:0006545 glycine biosynthetic process(GO:0006545)
2.0 4.0 GO:0019323 pentose catabolic process(GO:0019323)
2.0 2.0 GO:1901656 glycoside transport(GO:1901656)
2.0 6.0 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
2.0 5.9 GO:0006532 aspartate biosynthetic process(GO:0006532)
2.0 21.8 GO:0050912 detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
2.0 7.9 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
2.0 7.9 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
2.0 5.9 GO:0010193 response to ozone(GO:0010193)
2.0 5.9 GO:0002922 positive regulation of humoral immune response(GO:0002922)
2.0 11.8 GO:0051661 maintenance of centrosome location(GO:0051661)
1.9 17.5 GO:0071447 cellular response to hydroperoxide(GO:0071447)
1.9 5.8 GO:2000541 positive regulation of synaptic growth at neuromuscular junction(GO:0045887) regulation of protein geranylgeranylation(GO:2000539) positive regulation of protein geranylgeranylation(GO:2000541)
1.9 55.8 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
1.9 9.6 GO:0061085 regulation of histone H3-K27 methylation(GO:0061085)
1.9 11.4 GO:0060527 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
1.9 5.7 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
1.9 46.9 GO:0006270 DNA replication initiation(GO:0006270)
1.9 7.5 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
1.9 13.1 GO:2000210 positive regulation of anoikis(GO:2000210)
1.9 1.9 GO:1905132 metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
1.8 7.4 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
1.8 18.4 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
1.8 12.8 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
1.8 9.2 GO:0002675 positive regulation of acute inflammatory response(GO:0002675)
1.8 11.0 GO:0006308 DNA catabolic process(GO:0006308)
1.8 7.3 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
1.8 19.8 GO:0051014 actin filament severing(GO:0051014)
1.8 1.8 GO:0021603 cranial nerve formation(GO:0021603)
1.8 91.3 GO:0090501 RNA phosphodiester bond hydrolysis(GO:0090501)
1.8 7.2 GO:0070828 heterochromatin organization(GO:0070828)
1.8 14.3 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
1.8 5.3 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
1.8 5.3 GO:0051409 response to nitrosative stress(GO:0051409)
1.8 3.5 GO:0031448 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
1.8 5.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
1.8 10.5 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
1.8 21.0 GO:0043968 histone H2A acetylation(GO:0043968)
1.7 3.5 GO:0032258 CVT pathway(GO:0032258)
1.7 5.2 GO:2000542 negative regulation of endodermal cell differentiation(GO:1903225) negative regulation of gastrulation(GO:2000542)
1.7 13.9 GO:0098734 macromolecule depalmitoylation(GO:0098734)
1.7 3.5 GO:0046601 positive regulation of centriole replication(GO:0046601)
1.7 3.5 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
1.7 12.1 GO:0030259 lipid glycosylation(GO:0030259)
1.7 3.4 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
1.7 5.2 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
1.7 12.0 GO:0033119 negative regulation of RNA splicing(GO:0033119)
1.7 5.1 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
1.7 1.7 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
1.7 5.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
1.7 57.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
1.7 16.9 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
1.7 3.4 GO:0032916 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916)
1.7 6.7 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
1.7 5.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
1.7 5.1 GO:0032727 positive regulation of interferon-alpha production(GO:0032727)
1.7 16.8 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
1.7 1.7 GO:0042256 mature ribosome assembly(GO:0042256)
1.7 5.0 GO:0021539 subthalamus development(GO:0021539)
1.7 3.4 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
1.7 8.4 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
1.7 18.4 GO:1990845 adaptive thermogenesis(GO:1990845)
1.7 15.0 GO:0046599 regulation of centriole replication(GO:0046599)
1.7 3.3 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
1.6 3.3 GO:0071400 cellular response to oleic acid(GO:0071400)
1.6 1.6 GO:0021997 neural plate axis specification(GO:0021997)
1.6 9.8 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
1.6 1.6 GO:1904587 response to glycoprotein(GO:1904587)
1.6 6.5 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
1.6 3.2 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
1.6 3.2 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
1.6 8.1 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
1.6 71.0 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
1.6 14.5 GO:0071044 histone mRNA catabolic process(GO:0071044)
1.6 8.1 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
1.6 27.3 GO:0050728 negative regulation of inflammatory response(GO:0050728)
1.6 9.6 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
1.6 4.8 GO:0018199 peptidyl-glutamine modification(GO:0018199)
1.6 3.2 GO:0046292 formaldehyde metabolic process(GO:0046292)
1.6 4.8 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
1.6 4.8 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
1.6 1.6 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
1.6 1.6 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
1.6 3.2 GO:0007493 endodermal cell fate determination(GO:0007493) negative regulation of transforming growth factor beta2 production(GO:0032912)
1.6 14.3 GO:0018298 protein-chromophore linkage(GO:0018298)
1.6 4.8 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
1.6 6.3 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
1.6 7.9 GO:0035588 G-protein coupled purinergic receptor signaling pathway(GO:0035588)
1.6 6.3 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
1.6 9.4 GO:0097068 response to thyroxine(GO:0097068)
1.6 6.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
1.6 7.8 GO:0033194 response to hydroperoxide(GO:0033194)
1.6 3.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
1.6 18.7 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
1.6 21.8 GO:0034508 centromere complex assembly(GO:0034508)
1.5 7.7 GO:0007144 female meiosis I(GO:0007144)
1.5 10.7 GO:0007603 phototransduction, visible light(GO:0007603)
1.5 1.5 GO:0044209 AMP salvage(GO:0044209)
1.5 12.2 GO:0090224 regulation of mitotic spindle organization(GO:0060236) regulation of spindle organization(GO:0090224)
1.5 12.2 GO:0045056 transcytosis(GO:0045056)
1.5 3.0 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
1.5 1.5 GO:0006553 lysine metabolic process(GO:0006553)
1.5 16.6 GO:0035855 megakaryocyte development(GO:0035855)
1.5 4.5 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
1.5 3.0 GO:0014908 myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
1.5 7.4 GO:0000066 mitochondrial ornithine transport(GO:0000066)
1.5 3.0 GO:0010040 response to iron(II) ion(GO:0010040)
1.5 3.0 GO:0097037 heme export(GO:0097037)
1.5 3.0 GO:0000012 single strand break repair(GO:0000012)
1.5 4.4 GO:0006290 pyrimidine dimer repair(GO:0006290)
1.5 4.4 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
1.5 8.8 GO:0032717 negative regulation of interleukin-8 production(GO:0032717)
1.5 7.3 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
1.5 8.8 GO:0046146 tetrahydrobiopterin metabolic process(GO:0046146)
1.5 4.4 GO:0042088 T-helper 1 type immune response(GO:0042088)
1.5 4.4 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
1.5 7.3 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
1.5 45.0 GO:0051310 metaphase plate congression(GO:0051310)
1.4 8.6 GO:0035743 CD4-positive, alpha-beta T cell cytokine production(GO:0035743)
1.4 1.4 GO:0071027 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
1.4 2.9 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
1.4 5.7 GO:0048664 neuron fate determination(GO:0048664)
1.4 109.0 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
1.4 8.5 GO:0015677 copper ion import(GO:0015677)
1.4 8.5 GO:0006999 nuclear pore organization(GO:0006999)
1.4 5.6 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
1.4 4.2 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
1.4 76.9 GO:0006334 nucleosome assembly(GO:0006334)
1.4 23.6 GO:0009303 rRNA transcription(GO:0009303)
1.4 11.1 GO:0006021 inositol biosynthetic process(GO:0006021)
1.4 5.5 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
1.4 4.1 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
1.4 2.8 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
1.4 2.7 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
1.4 1.4 GO:1901073 glucosamine-containing compound biosynthetic process(GO:1901073)
1.4 4.1 GO:0007296 vitellogenesis(GO:0007296)
1.4 4.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
1.3 5.4 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
1.3 10.8 GO:0009130 UMP biosynthetic process(GO:0006222) pyrimidine nucleoside monophosphate biosynthetic process(GO:0009130) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
1.3 2.7 GO:0000393 generation of catalytic spliceosome for second transesterification step(GO:0000350) spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
1.3 9.3 GO:0035067 negative regulation of histone acetylation(GO:0035067)
1.3 8.0 GO:0032986 protein-DNA complex disassembly(GO:0032986)
1.3 13.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
1.3 4.0 GO:0045764 positive regulation of cellular amino acid metabolic process(GO:0045764)
1.3 1.3 GO:0045910 negative regulation of DNA recombination(GO:0045910)
1.3 9.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
1.3 23.8 GO:0045576 mast cell activation(GO:0045576)
1.3 5.3 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
1.3 7.9 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
1.3 3.9 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
1.3 11.8 GO:0045738 negative regulation of DNA repair(GO:0045738) negative regulation of double-strand break repair(GO:2000780)
1.3 5.2 GO:0042976 activation of Janus kinase activity(GO:0042976)
1.3 14.3 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
1.3 2.6 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
1.3 3.9 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
1.3 6.5 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
1.3 3.9 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
1.3 3.9 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
1.3 3.9 GO:0006574 valine catabolic process(GO:0006574)
1.3 3.9 GO:2000853 negative regulation of corticosterone secretion(GO:2000853)
1.3 8.9 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
1.3 2.5 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
1.3 2.5 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802) regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803)
1.3 2.5 GO:0031860 telomeric 3' overhang formation(GO:0031860)
1.3 2.5 GO:0010833 telomere maintenance via telomere lengthening(GO:0010833)
1.3 3.8 GO:0070232 regulation of T cell apoptotic process(GO:0070232)
1.2 2.5 GO:0016445 somatic diversification of immunoglobulins(GO:0016445)
1.2 24.7 GO:0006805 xenobiotic metabolic process(GO:0006805)
1.2 7.4 GO:0045002 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
1.2 6.1 GO:0006776 vitamin A metabolic process(GO:0006776)
1.2 3.7 GO:0048254 snoRNA localization(GO:0048254)
1.2 3.6 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
1.2 6.0 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
1.2 16.7 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
1.2 1.2 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
1.2 9.5 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
1.2 8.3 GO:0090435 protein localization to nuclear envelope(GO:0090435)
1.2 19.0 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
1.2 4.7 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
1.2 3.5 GO:0070673 response to interleukin-18(GO:0070673)
1.2 7.1 GO:0000722 telomere maintenance via recombination(GO:0000722)
1.2 3.5 GO:0006824 cobalt ion transport(GO:0006824)
1.2 5.9 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
1.2 7.0 GO:0006353 DNA-templated transcription, termination(GO:0006353)
1.2 24.6 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
1.2 12.9 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
1.2 2.3 GO:0010070 zygote asymmetric cell division(GO:0010070)
1.2 8.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
1.2 10.5 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
1.2 4.6 GO:1902570 protein localization to nucleolus(GO:1902570)
1.2 6.9 GO:0018206 peptidyl-methionine modification(GO:0018206)
1.2 2.3 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
1.2 4.6 GO:0046836 glycolipid transport(GO:0046836)
1.2 5.8 GO:0045820 negative regulation of glycolytic process(GO:0045820)
1.1 4.6 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
1.1 4.6 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
1.1 2.3 GO:0014028 notochord formation(GO:0014028)
1.1 3.4 GO:0060486 Clara cell differentiation(GO:0060486)
1.1 3.4 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
1.1 20.2 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
1.1 10.1 GO:0050872 white fat cell differentiation(GO:0050872)
1.1 7.8 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
1.1 11.1 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
1.1 11.1 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
1.1 1.1 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
1.1 12.1 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
1.1 59.2 GO:0031638 zymogen activation(GO:0031638)
1.1 4.4 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
1.1 3.3 GO:0033505 floor plate morphogenesis(GO:0033505)
1.1 17.4 GO:0006491 N-glycan processing(GO:0006491)
1.1 5.4 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
1.1 22.8 GO:0030183 B cell differentiation(GO:0030183)
1.1 14.1 GO:0007099 centriole replication(GO:0007099)
1.1 2.2 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
1.1 2.2 GO:1903699 histone H3-K36 dimethylation(GO:0097676) tarsal gland development(GO:1903699)
1.1 6.5 GO:0042635 positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
1.1 7.5 GO:0045616 regulation of keratinocyte differentiation(GO:0045616)
1.1 7.5 GO:0000956 nuclear-transcribed mRNA catabolic process(GO:0000956)
1.1 7.5 GO:0051451 myoblast migration(GO:0051451)
1.1 10.7 GO:0006012 galactose metabolic process(GO:0006012)
1.1 2.1 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
1.1 4.2 GO:0002525 acute inflammatory response to non-antigenic stimulus(GO:0002525)
1.1 514.6 GO:0006412 translation(GO:0006412)
1.1 2.1 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
1.1 4.2 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
1.1 2.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
1.1 11.6 GO:0019369 arachidonic acid metabolic process(GO:0019369)
1.0 25.2 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
1.0 4.2 GO:1902534 single-organism membrane invagination(GO:1902534)
1.0 1.0 GO:0090648 response to environmental enrichment(GO:0090648)
1.0 5.2 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
1.0 4.2 GO:0044351 macropinocytosis(GO:0044351)
1.0 8.3 GO:0030490 maturation of SSU-rRNA(GO:0030490)
1.0 5.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
1.0 4.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
1.0 3.1 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
1.0 2.1 GO:0070189 kynurenine metabolic process(GO:0070189)
1.0 2.1 GO:0042414 epinephrine metabolic process(GO:0042414)
1.0 3.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
1.0 4.1 GO:0051958 methotrexate transport(GO:0051958)
1.0 2.0 GO:0042780 tRNA 3'-end processing(GO:0042780)
1.0 2.0 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
1.0 2.0 GO:0019249 lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
1.0 1.0 GO:0015809 arginine transport(GO:0015809)
1.0 380.0 GO:0006955 immune response(GO:0006955)
1.0 6.0 GO:0035372 protein localization to microtubule(GO:0035372)
1.0 7.9 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
1.0 6.9 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
1.0 2.9 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
1.0 4.9 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
1.0 2.9 GO:2000382 positive regulation of mesoderm development(GO:2000382)
1.0 2.9 GO:0010041 response to iron(III) ion(GO:0010041)
1.0 3.9 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
1.0 4.9 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
1.0 4.8 GO:0033384 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384)
1.0 5.8 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
1.0 1.0 GO:0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
0.9 5.7 GO:0006868 glutamine transport(GO:0006868)
0.9 2.8 GO:0042851 L-alanine metabolic process(GO:0042851)
0.9 1.9 GO:1901318 negative regulation of sperm motility(GO:1901318)
0.9 0.9 GO:0040009 regulation of growth rate(GO:0040009)
0.9 6.6 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.9 10.3 GO:0001675 acrosome assembly(GO:0001675)
0.9 0.9 GO:0002930 trabecular meshwork development(GO:0002930)
0.9 8.4 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.9 2.8 GO:0071168 protein localization to chromatin(GO:0071168)
0.9 1.8 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.9 2.7 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.9 3.6 GO:0060005 vestibular reflex(GO:0060005)
0.9 14.4 GO:0009584 detection of visible light(GO:0009584)
0.9 1.8 GO:0031663 lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.9 5.3 GO:0034312 diol biosynthetic process(GO:0034312)
0.9 5.3 GO:0034214 protein hexamerization(GO:0034214)
0.9 4.4 GO:0034227 tRNA thio-modification(GO:0034227)
0.9 1.7 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.9 1.7 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.9 1.7 GO:0060760 positive regulation of response to cytokine stimulus(GO:0060760)
0.9 4.3 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.9 1.7 GO:0019448 cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.8 4.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.8 2.5 GO:0070417 cellular response to cold(GO:0070417)
0.8 3.4 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.8 1.7 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.8 1.7 GO:0070084 protein initiator methionine removal(GO:0070084)
0.8 9.2 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.8 0.8 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.8 5.0 GO:0006517 protein deglycosylation(GO:0006517)
0.8 2.5 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.8 4.1 GO:0009750 response to fructose(GO:0009750)
0.8 0.8 GO:0031627 telomeric loop formation(GO:0031627)
0.8 2.5 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.8 4.1 GO:0002548 monocyte chemotaxis(GO:0002548)
0.8 2.5 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.8 4.1 GO:0030261 chromosome condensation(GO:0030261)
0.8 1.6 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454) rRNA pseudouridine synthesis(GO:0031118)
0.8 3.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.8 9.8 GO:0043277 apoptotic cell clearance(GO:0043277)
0.8 13.0 GO:0048240 sperm capacitation(GO:0048240)
0.8 1.6 GO:0045297 mating plug formation(GO:0042628) post-mating behavior(GO:0045297)
0.8 0.8 GO:0035262 gonad morphogenesis(GO:0035262)
0.8 4.1 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.8 13.0 GO:0008206 bile acid metabolic process(GO:0008206)
0.8 7.9 GO:0006544 glycine metabolic process(GO:0006544)
0.8 5.5 GO:0030851 granulocyte differentiation(GO:0030851)
0.8 0.8 GO:0072711 cellular response to hydroxyurea(GO:0072711)
0.8 2.3 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.8 0.8 GO:0060018 astrocyte fate commitment(GO:0060018)
0.8 6.2 GO:0006783 heme biosynthetic process(GO:0006783)
0.8 3.9 GO:1904948 midbrain dopaminergic neuron differentiation(GO:1904948)
0.8 1.6 GO:0042255 ribosome assembly(GO:0042255)
0.8 7.0 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.8 4.6 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.8 0.8 GO:0001555 oocyte growth(GO:0001555)
0.8 0.8 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.8 5.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.7 0.7 GO:0090172 microtubule cytoskeleton organization involved in homologous chromosome segregation(GO:0090172)
0.7 3.7 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.7 3.0 GO:0022417 protein maturation by protein folding(GO:0022417)
0.7 17.1 GO:0006611 protein export from nucleus(GO:0006611)
0.7 1.5 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.7 4.4 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.7 0.7 GO:0043038 amino acid activation(GO:0043038)
0.7 3.7 GO:0048368 lateral mesoderm development(GO:0048368)
0.7 3.7 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.7 2.9 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.7 1.4 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.7 6.4 GO:0060009 Sertoli cell development(GO:0060009)
0.7 8.5 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.7 12.7 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.7 2.8 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.7 3.5 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.7 1.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.7 1.4 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.7 10.4 GO:0016180 snRNA processing(GO:0016180)
0.7 5.5 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.7 2.1 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.7 1.4 GO:1904426 positive regulation of GTP binding(GO:1904426)
0.7 4.1 GO:0055070 copper ion homeostasis(GO:0055070)
0.7 0.7 GO:0070475 rRNA base methylation(GO:0070475)
0.7 0.7 GO:0072143 renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.7 1.4 GO:1904823 purine nucleobase transmembrane transport(GO:1904823)
0.7 0.7 GO:0009650 UV protection(GO:0009650)
0.7 1.3 GO:2001160 histone H3-K79 methylation(GO:0034729) regulation of histone H3-K79 methylation(GO:2001160)
0.7 2.7 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.7 2.0 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.7 3.3 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.7 3.3 GO:0042359 vitamin D metabolic process(GO:0042359)
0.7 6.6 GO:2000772 regulation of cellular senescence(GO:2000772)
0.7 5.9 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.7 0.7 GO:0008298 intracellular mRNA localization(GO:0008298)
0.7 0.7 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.7 3.9 GO:0080009 mRNA methylation(GO:0080009)
0.6 0.6 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.6 62.0 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.6 2.6 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.6 1.3 GO:0070813 hydrogen sulfide metabolic process(GO:0070813)
0.6 5.7 GO:0048536 spleen development(GO:0048536)
0.6 24.6 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.6 12.6 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.6 2.4 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.6 1.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.6 1.2 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.6 12.2 GO:0007004 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.6 0.6 GO:0060900 optic cup morphogenesis involved in camera-type eye development(GO:0002072) embryonic camera-type eye formation(GO:0060900)
0.6 2.4 GO:0021633 optic nerve structural organization(GO:0021633)
0.6 1.2 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.6 1.2 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.6 2.9 GO:0016266 O-glycan processing(GO:0016266)
0.6 24.6 GO:0090305 nucleic acid phosphodiester bond hydrolysis(GO:0090305)
0.6 1.7 GO:1902751 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.6 1.1 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.6 1.7 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.6 0.6 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.6 1.7 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.6 1.7 GO:0006983 ER overload response(GO:0006983)
0.5 0.5 GO:0046113 nucleobase catabolic process(GO:0046113)
0.5 0.5 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.5 1.1 GO:0051660 establishment of centrosome localization(GO:0051660)
0.5 1.6 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.5 2.7 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.5 2.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.5 1.6 GO:0070914 UV-damage excision repair(GO:0070914)
0.5 0.5 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.5 1.0 GO:0060327 cytoplasmic actin-based contraction involved in cell motility(GO:0060327)
0.5 2.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.5 2.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.5 1.0 GO:0038171 cannabinoid signaling pathway(GO:0038171)
0.5 0.5 GO:0038129 ERBB3 signaling pathway(GO:0038129)
0.5 2.6 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.5 1.5 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.5 5.4 GO:0006378 mRNA polyadenylation(GO:0006378)
0.5 1.0 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.5 2.0 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
0.5 2.0 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.5 1.0 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.5 0.5 GO:0045054 constitutive secretory pathway(GO:0045054)
0.5 2.9 GO:0007143 female meiotic division(GO:0007143)
0.5 0.5 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.5 5.1 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.5 0.5 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.5 1.8 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.4 6.7 GO:0043248 proteasome assembly(GO:0043248)
0.4 6.2 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.4 0.9 GO:0006567 threonine catabolic process(GO:0006567)
0.4 0.4 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.4 0.4 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.4 3.0 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.4 2.1 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.4 1.3 GO:0070314 G1 to G0 transition(GO:0070314)
0.4 0.8 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.4 0.8 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.4 0.8 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.4 0.8 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
0.4 1.2 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.4 0.8 GO:0046100 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.4 0.8 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.4 2.3 GO:0043486 histone exchange(GO:0043486)
0.4 1.1 GO:0060014 granulosa cell differentiation(GO:0060014)
0.4 0.4 GO:1902309 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043) negative regulation of peptidyl-serine dephosphorylation(GO:1902309) regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.4 2.3 GO:1902622 regulation of neutrophil migration(GO:1902622)
0.4 3.8 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.4 0.4 GO:0036093 germ cell proliferation(GO:0036093)
0.4 2.6 GO:0031297 replication fork processing(GO:0031297)
0.4 0.7 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.4 1.5 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.4 4.4 GO:0006541 glutamine metabolic process(GO:0006541)
0.4 1.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.4 1.4 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.4 1.1 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.4 0.7 GO:0005984 disaccharide metabolic process(GO:0005984)
0.4 2.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.3 1.7 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.3 1.4 GO:0046040 IMP metabolic process(GO:0046040)
0.3 0.7 GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.3 1.7 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.3 0.7 GO:0033700 phospholipid efflux(GO:0033700)
0.3 0.7 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.3 5.9 GO:0009988 cell-cell recognition(GO:0009988)
0.3 0.3 GO:0010157 response to chlorate(GO:0010157)
0.3 0.6 GO:0030091 protein repair(GO:0030091)
0.3 0.6 GO:0018963 phthalate metabolic process(GO:0018963)
0.3 0.6 GO:0042412 taurine biosynthetic process(GO:0042412)
0.3 6.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.3 0.3 GO:1903894 regulation of IRE1-mediated unfolded protein response(GO:1903894)
0.3 2.6 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.3 0.3 GO:0006408 snRNA export from nucleus(GO:0006408)
0.3 1.1 GO:0019321 pentose metabolic process(GO:0019321)
0.3 1.1 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.3 1.4 GO:0043482 endosome to melanosome transport(GO:0035646) pigment accumulation(GO:0043476) cellular pigment accumulation(GO:0043482) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.3 0.8 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.3 2.4 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.3 0.8 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.3 4.1 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.3 2.1 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.3 0.5 GO:0043418 homocysteine catabolic process(GO:0043418)
0.3 7.0 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.2 1.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.2 1.0 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.2 0.5 GO:0006552 leucine catabolic process(GO:0006552)
0.2 1.2 GO:0070875 positive regulation of glycogen biosynthetic process(GO:0045725) positive regulation of glycogen metabolic process(GO:0070875)
0.2 0.2 GO:1904313 response to methamphetamine hydrochloride(GO:1904313)
0.2 2.5 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.2 0.9 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.2 0.7 GO:0032474 otolith morphogenesis(GO:0032474)
0.2 1.4 GO:0015866 ADP transport(GO:0015866)
0.2 0.7 GO:0051444 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.2 0.7 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.2 0.4 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.2 0.7 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.2 0.8 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.2 1.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.2 2.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 1.0 GO:0032508 DNA duplex unwinding(GO:0032508)
0.2 0.4 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.2 0.6 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.2 3.8 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.2 0.4 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.2 0.9 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413)
0.2 0.3 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.2 0.2 GO:0072162 metanephric mesenchymal cell differentiation(GO:0072162)
0.2 0.7 GO:0030730 sequestering of triglyceride(GO:0030730)
0.2 0.7 GO:0046884 follicle-stimulating hormone secretion(GO:0046884)
0.2 0.9 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.2 0.5 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.2 0.6 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 0.3 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.1 0.8 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.1 0.7 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.9 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 0.5 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.2 GO:0051974 negative regulation of telomerase activity(GO:0051974)
0.1 0.4 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.1 1.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 2.1 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.1 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 1.8 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.1 0.2 GO:0030242 pexophagy(GO:0030242)
0.1 0.5 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.1 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.1 0.3 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 0.2 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.0 0.1 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.5 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.2 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:0006220 pyrimidine nucleotide metabolic process(GO:0006220)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
29.0 232.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
23.0 115.0 GO:0072557 IPAF inflammasome complex(GO:0072557)
18.8 75.0 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
17.2 172.0 GO:0042101 T cell receptor complex(GO:0042101)
16.9 33.8 GO:0097169 AIM2 inflammasome complex(GO:0097169)
16.9 50.6 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
16.0 256.4 GO:0042613 MHC class II protein complex(GO:0042613)
15.9 143.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
15.3 61.1 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
15.0 60.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
13.6 40.9 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
13.5 40.6 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
13.5 80.8 GO:0005579 membrane attack complex(GO:0005579)
13.3 53.0 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
12.3 135.6 GO:0005833 hemoglobin complex(GO:0005833)
11.7 70.0 GO:0097342 ripoptosome(GO:0097342)
11.4 320.4 GO:0000788 nuclear nucleosome(GO:0000788)
11.1 22.2 GO:0036398 TCR signalosome(GO:0036398)
10.6 42.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
10.5 31.4 GO:0032398 MHC class Ib protein complex(GO:0032398)
9.9 29.8 GO:1990423 RZZ complex(GO:1990423)
9.8 29.4 GO:0019814 immunoglobulin complex(GO:0019814) B cell receptor complex(GO:0019815)
9.8 39.0 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
9.6 9.6 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
9.2 73.6 GO:0005577 fibrinogen complex(GO:0005577)
8.8 964.0 GO:0072562 blood microparticle(GO:0072562)
8.1 24.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
7.9 23.8 GO:0000811 GINS complex(GO:0000811)
7.8 62.7 GO:0000796 condensin complex(GO:0000796)
7.8 242.9 GO:0042588 zymogen granule(GO:0042588)
7.4 66.3 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
7.3 87.1 GO:0042612 MHC class I protein complex(GO:0042612)
7.1 92.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
7.1 247.5 GO:0001772 immunological synapse(GO:0001772)
7.1 106.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
6.7 13.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
6.6 52.8 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
6.4 19.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
6.4 446.0 GO:0000786 nucleosome(GO:0000786)
6.3 31.7 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
6.3 1859.2 GO:0009897 external side of plasma membrane(GO:0009897)
6.3 31.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
6.2 18.5 GO:0008537 proteasome activator complex(GO:0008537)
6.2 30.9 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
6.0 30.0 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
5.8 17.4 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
5.8 17.4 GO:0070821 tertiary granule membrane(GO:0070821)
5.6 22.2 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
5.6 22.2 GO:0030478 actin cap(GO:0030478)
5.5 33.3 GO:0005663 DNA replication factor C complex(GO:0005663)
5.5 27.6 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
5.5 38.6 GO:0005683 U7 snRNP(GO:0005683)
5.5 22.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
5.3 42.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
5.2 20.8 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
5.2 10.3 GO:0032133 chromosome passenger complex(GO:0032133)
5.1 5.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
5.0 34.8 GO:0042824 MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
5.0 39.7 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
5.0 14.9 GO:0070826 paraferritin complex(GO:0070826)
4.8 23.9 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
4.8 19.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
4.7 47.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
4.7 18.8 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
4.7 337.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
4.7 14.0 GO:1990826 nucleoplasmic periphery of the nuclear pore complex(GO:1990826)
4.7 18.6 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
4.6 64.8 GO:0031616 spindle pole centrosome(GO:0031616)
4.6 97.2 GO:0042629 mast cell granule(GO:0042629)
4.5 45.0 GO:0031080 nuclear pore outer ring(GO:0031080)
4.5 433.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
4.4 30.8 GO:0097524 sperm plasma membrane(GO:0097524)
4.3 13.0 GO:0055087 Ski complex(GO:0055087)
4.3 13.0 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
4.3 25.5 GO:0005672 transcription factor TFIIA complex(GO:0005672)
4.2 21.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
4.2 21.1 GO:0070195 growth hormone receptor complex(GO:0070195)
4.2 12.5 GO:0097651 phosphatidylinositol 3-kinase complex, class IA(GO:0005943) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
4.2 16.7 GO:0097149 centralspindlin complex(GO:0097149)
4.2 62.3 GO:0070938 contractile ring(GO:0070938)
4.1 4.1 GO:0030870 Mre11 complex(GO:0030870)
4.1 53.0 GO:0046581 intercellular canaliculus(GO:0046581)
4.0 11.9 GO:0071149 TEAD-2-YAP complex(GO:0071149)
4.0 11.9 GO:0033186 CAF-1 complex(GO:0033186)
3.9 7.7 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
3.8 23.0 GO:0000974 Prp19 complex(GO:0000974)
3.8 11.5 GO:0031262 Ndc80 complex(GO:0031262)
3.8 7.6 GO:0008278 cohesin complex(GO:0008278)
3.7 40.4 GO:0042555 MCM complex(GO:0042555)
3.5 24.5 GO:0005687 U4 snRNP(GO:0005687)
3.4 20.4 GO:0031904 endosome lumen(GO:0031904)
3.4 20.3 GO:1990111 spermatoproteasome complex(GO:1990111)
3.3 16.3 GO:0034455 t-UTP complex(GO:0034455)
3.2 41.9 GO:0000801 central element(GO:0000801)
3.2 9.5 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
3.2 82.0 GO:0035145 exon-exon junction complex(GO:0035145)
3.1 9.4 GO:1990682 CSF1-CSF1R complex(GO:1990682)
3.1 58.9 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
3.1 12.3 GO:0044299 C-fiber(GO:0044299)
3.0 42.4 GO:0030894 DNA replication factor A complex(GO:0005662) replisome(GO:0030894) nuclear replisome(GO:0043601)
3.0 12.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
3.0 9.0 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
3.0 9.0 GO:0033093 Weibel-Palade body(GO:0033093)
2.9 2.9 GO:0033290 eukaryotic 48S preinitiation complex(GO:0033290)
2.9 11.7 GO:0000938 GARP complex(GO:0000938)
2.9 17.5 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
2.9 17.2 GO:0031298 replication fork protection complex(GO:0031298)
2.8 25.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
2.8 25.5 GO:0031010 ISWI-type complex(GO:0031010)
2.8 64.4 GO:0005721 pericentric heterochromatin(GO:0005721)
2.8 19.6 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
2.7 8.2 GO:0005726 perichromatin fibrils(GO:0005726)
2.7 10.7 GO:0034774 secretory granule lumen(GO:0034774)
2.7 58.6 GO:0005657 replication fork(GO:0005657)
2.6 10.6 GO:1990005 granular vesicle(GO:1990005)
2.6 26.1 GO:0043020 NADPH oxidase complex(GO:0043020)
2.6 40.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
2.5 10.2 GO:0035339 SPOTS complex(GO:0035339)
2.5 17.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
2.4 7.3 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
2.4 17.0 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
2.3 11.7 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
2.3 23.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
2.3 13.8 GO:0036128 CatSper complex(GO:0036128)
2.3 36.8 GO:0035686 sperm fibrous sheath(GO:0035686)
2.3 6.9 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
2.3 27.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
2.3 6.8 GO:0044530 supraspliceosomal complex(GO:0044530)
2.3 15.8 GO:0070449 elongin complex(GO:0070449)
2.3 11.3 GO:0097165 nuclear stress granule(GO:0097165)
2.2 53.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
2.2 57.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
2.2 15.5 GO:0016600 flotillin complex(GO:0016600)
2.2 6.6 GO:0005899 insulin receptor complex(GO:0005899)
2.2 15.5 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
2.2 2.2 GO:0070993 translation preinitiation complex(GO:0070993)
2.2 24.1 GO:0042581 specific granule(GO:0042581)
2.2 19.7 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
2.2 10.9 GO:0005642 annulate lamellae(GO:0005642)
2.2 8.7 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
2.2 15.2 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
2.2 12.9 GO:0097209 epidermal lamellar body(GO:0097209)
2.2 4.3 GO:0042585 germinal vesicle(GO:0042585)
2.1 12.8 GO:0032444 activin responsive factor complex(GO:0032444)
2.1 6.4 GO:0033165 interphotoreceptor matrix(GO:0033165)
2.1 21.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
2.1 23.3 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
2.1 6.4 GO:0044611 nuclear pore inner ring(GO:0044611)
2.1 14.8 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
2.1 8.4 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
2.1 16.7 GO:0097550 transcriptional preinitiation complex(GO:0097550)
2.1 8.4 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
2.1 41.6 GO:0030057 desmosome(GO:0030057)
2.1 6.2 GO:0005760 gamma DNA polymerase complex(GO:0005760)
2.1 153.6 GO:0045095 keratin filament(GO:0045095)
2.0 12.3 GO:0030677 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
2.0 13.9 GO:0031415 NatA complex(GO:0031415)
2.0 2.0 GO:0000798 nuclear cohesin complex(GO:0000798)
2.0 2.0 GO:0020003 symbiont-containing vacuole(GO:0020003)
2.0 9.8 GO:0090543 Flemming body(GO:0090543)
1.9 7.8 GO:0030121 AP-1 adaptor complex(GO:0030121)
1.9 34.9 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
1.9 34.6 GO:0046930 pore complex(GO:0046930)
1.9 9.6 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
1.9 9.6 GO:0035061 interchromatin granule(GO:0035061)
1.9 7.6 GO:0045098 type III intermediate filament(GO:0045098)
1.9 5.7 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
1.9 13.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
1.9 41.1 GO:0001891 phagocytic cup(GO:0001891)
1.9 5.6 GO:0070531 BRCA1-A complex(GO:0070531)
1.8 59.1 GO:0005720 nuclear heterochromatin(GO:0005720)
1.8 86.1 GO:0005643 nuclear pore(GO:0005643)
1.8 1.8 GO:0032807 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807) nonhomologous end joining complex(GO:0070419)
1.8 5.3 GO:0070421 DNA ligase III-XRCC1 complex(GO:0070421)
1.7 18.8 GO:0008385 IkappaB kinase complex(GO:0008385)
1.7 32.5 GO:0030056 hemidesmosome(GO:0030056)
1.7 6.8 GO:0070552 BRISC complex(GO:0070552)
1.7 3.4 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
1.7 5.0 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
1.7 11.7 GO:0001939 female pronucleus(GO:0001939)
1.6 28.9 GO:0005689 U12-type spliceosomal complex(GO:0005689)
1.6 9.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
1.6 1.6 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
1.5 60.0 GO:0016235 aggresome(GO:0016235)
1.5 6.1 GO:0005675 holo TFIIH complex(GO:0005675)
1.5 9.2 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
1.5 15.2 GO:0044754 autolysosome(GO:0044754)
1.5 25.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
1.5 3.0 GO:0001651 dense fibrillar component(GO:0001651)
1.5 3.0 GO:0070761 pre-snoRNP complex(GO:0070761)
1.5 22.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
1.5 8.9 GO:0071547 piP-body(GO:0071547)
1.5 4.4 GO:0031308 intrinsic component of nuclear outer membrane(GO:0031308) integral component of nuclear outer membrane(GO:0031309)
1.5 2.9 GO:0033588 Elongator holoenzyme complex(GO:0033588)
1.5 5.8 GO:0033553 rDNA heterochromatin(GO:0033553)
1.4 10.1 GO:0032806 carboxy-terminal domain protein kinase complex(GO:0032806)
1.4 5.7 GO:0000322 storage vacuole(GO:0000322)
1.4 59.0 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
1.4 11.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
1.4 4.1 GO:0043511 inhibin complex(GO:0043511)
1.4 8.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
1.4 12.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
1.4 6.8 GO:0051286 cell tip(GO:0051286)
1.3 32.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
1.3 14.7 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
1.3 8.0 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
1.3 9.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
1.3 5.2 GO:0005588 collagen type V trimer(GO:0005588)
1.3 14.3 GO:0001673 male germ cell nucleus(GO:0001673)
1.3 5.1 GO:0097422 tubular endosome(GO:0097422)
1.3 17.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
1.3 5.0 GO:0070876 SOSS complex(GO:0070876)
1.2 5.0 GO:0097413 Lewy body(GO:0097413)
1.2 12.4 GO:0031528 microvillus membrane(GO:0031528)
1.2 8.5 GO:0005828 kinetochore microtubule(GO:0005828)
1.2 15.4 GO:0030014 CCR4-NOT complex(GO:0030014)
1.2 24.8 GO:0000795 synaptonemal complex(GO:0000795)
1.2 4.7 GO:0042382 paraspeckles(GO:0042382)
1.2 103.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
1.2 280.3 GO:0005667 transcription factor complex(GO:0005667)
1.2 10.5 GO:0044215 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
1.2 2.3 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
1.1 3.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
1.1 84.4 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
1.1 6.7 GO:0097431 mitotic spindle pole(GO:0097431)
1.1 14.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
1.1 11.1 GO:0019013 viral nucleocapsid(GO:0019013)
1.1 166.1 GO:0005840 ribosome(GO:0005840)
1.1 31.2 GO:0000777 condensed chromosome kinetochore(GO:0000777)
1.1 4.2 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
1.0 15.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
1.0 4.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
1.0 14.0 GO:0032039 integrator complex(GO:0032039)
1.0 6.0 GO:0072687 meiotic spindle(GO:0072687)
1.0 4.8 GO:0098536 deuterosome(GO:0098536)
0.9 67.4 GO:0016605 PML body(GO:0016605)
0.9 1.9 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.9 0.9 GO:0005688 U6 snRNP(GO:0005688)
0.9 1151.8 GO:0005615 extracellular space(GO:0005615)
0.9 7.4 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.9 21.0 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.8 0.8 GO:0032994 protein-lipid complex(GO:0032994)
0.8 5.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.8 8.4 GO:0035102 PRC1 complex(GO:0035102)
0.8 10.9 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.8 14.9 GO:0005839 proteasome core complex(GO:0005839)
0.8 3.9 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.8 73.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.8 0.8 GO:0035577 azurophil granule membrane(GO:0035577)
0.8 0.8 GO:0000346 transcription export complex(GO:0000346)
0.7 4.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.7 7.1 GO:0016580 Sin3 complex(GO:0016580)
0.7 8.5 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.7 3.5 GO:0061617 MICOS complex(GO:0061617)
0.7 37.4 GO:0000781 chromosome, telomeric region(GO:0000781)
0.7 72.1 GO:0001650 fibrillar center(GO:0001650)
0.6 13.3 GO:0000152 nuclear ubiquitin ligase complex(GO:0000152)
0.6 1.9 GO:0072487 MSL complex(GO:0072487)
0.6 35.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.6 1.8 GO:0005940 septin ring(GO:0005940) septin collar(GO:0032173)
0.6 3.0 GO:1903767 sweet taste receptor complex(GO:1903767) taste receptor complex(GO:1903768)
0.6 8.8 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.6 4.7 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.6 30.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.6 1.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.6 4.5 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.5 3.6 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.5 1.0 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.5 5.3 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.5 23.5 GO:0000775 chromosome, centromeric region(GO:0000775)
0.5 1.4 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.5 1.8 GO:0071817 MMXD complex(GO:0071817)
0.5 0.9 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.4 1.3 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) fumarate reductase complex(GO:0045283)
0.4 0.9 GO:1990429 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.4 2.6 GO:0005638 lamin filament(GO:0005638)
0.4 0.9 GO:0036117 hyaluranon cable(GO:0036117)
0.4 5.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.4 1.3 GO:0030891 VCB complex(GO:0030891)
0.4 292.9 GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network(GO:0042175)
0.4 4.4 GO:0071564 npBAF complex(GO:0071564)
0.4 0.8 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.4 1.9 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.4 20.3 GO:0016363 nuclear matrix(GO:0016363)
0.4 1.5 GO:0031417 NatC complex(GO:0031417)
0.4 0.8 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.4 4.5 GO:0005861 troponin complex(GO:0005861)
0.4 12.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.4 1.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.4 16.2 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.4 2.9 GO:0000812 Swr1 complex(GO:0000812)
0.4 1.4 GO:0045120 pronucleus(GO:0045120)
0.4 2.8 GO:0035631 CD40 receptor complex(GO:0035631)
0.3 0.7 GO:0035355 Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.3 9.0 GO:0000502 proteasome complex(GO:0000502)
0.3 2.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.3 2.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.3 4.4 GO:0051233 spindle midzone(GO:0051233)
0.3 1.2 GO:0033503 HULC complex(GO:0033503)
0.3 1.7 GO:1990635 proximal dendrite(GO:1990635)
0.3 5.8 GO:0005844 polysome(GO:0005844)
0.3 2.7 GO:0070652 HAUS complex(GO:0070652)
0.2 3.2 GO:0031519 PcG protein complex(GO:0031519)
0.2 9.7 GO:0005811 lipid particle(GO:0005811)
0.2 1.3 GO:0045179 apical cortex(GO:0045179)
0.2 0.7 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.2 5.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.2 4.3 GO:0015030 Cajal body(GO:0015030)
0.2 4.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.2 1.0 GO:0000792 heterochromatin(GO:0000792)
0.2 1.1 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.4 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.5 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 1.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.6 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.6 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.3 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.2 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.4 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
66.9 200.6 GO:0004556 alpha-amylase activity(GO:0004556)
33.3 166.6 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
27.5 82.5 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
26.3 105.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
25.2 75.6 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
21.6 64.7 GO:0004522 ribonuclease A activity(GO:0004522)
20.6 123.8 GO:0019976 interleukin-2 binding(GO:0019976)
20.6 102.8 GO:0043120 tumor necrosis factor binding(GO:0043120)
19.4 58.3 GO:0031721 hemoglobin alpha binding(GO:0031721)
19.1 57.4 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
18.1 108.6 GO:0042289 MHC class II protein binding(GO:0042289)
17.5 525.2 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
17.5 70.0 GO:0019763 immunoglobulin receptor activity(GO:0019763)
17.4 52.1 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
17.4 52.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
17.2 51.5 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
17.0 68.0 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
16.4 49.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
15.6 483.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
15.2 91.1 GO:0019767 IgE receptor activity(GO:0019767)
15.0 60.1 GO:0045159 myosin II binding(GO:0045159)
14.8 44.5 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
14.3 358.2 GO:0042288 MHC class I protein binding(GO:0042288)
13.7 13.7 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
13.5 67.6 GO:0019862 IgA binding(GO:0019862)
13.4 120.6 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
12.5 75.0 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
12.4 74.5 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
12.1 36.3 GO:0019863 IgE binding(GO:0019863)
11.5 46.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
11.5 34.6 GO:0004566 beta-glucuronidase activity(GO:0004566)
11.3 33.8 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
11.3 11.3 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
11.2 89.6 GO:0003996 acyl-CoA ligase activity(GO:0003996)
11.1 44.4 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
11.0 44.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
11.0 32.9 GO:0019115 all-trans retinal binding(GO:0005503) benzaldehyde dehydrogenase activity(GO:0019115) S-(hydroxymethyl)glutathione dehydrogenase activity(GO:0051903)
10.8 43.2 GO:0042287 MHC protein binding(GO:0042287)
10.7 43.0 GO:0031493 nucleosomal histone binding(GO:0031493)
10.7 106.7 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
10.5 116.0 GO:0055102 lipase inhibitor activity(GO:0055102)
10.5 31.5 GO:0001069 regulatory region RNA binding(GO:0001069)
10.4 72.9 GO:0019238 cyclohydrolase activity(GO:0019238)
10.1 100.7 GO:0019957 C-C chemokine binding(GO:0019957)
9.7 67.6 GO:0035375 zymogen binding(GO:0035375)
9.6 28.8 GO:0008481 sphinganine kinase activity(GO:0008481)
9.5 28.6 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
9.4 28.3 GO:0015322 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
9.3 37.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
9.3 37.2 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
9.3 120.7 GO:1990405 protein antigen binding(GO:1990405)
9.0 36.1 GO:0047619 acylcarnitine hydrolase activity(GO:0047619)
9.0 17.9 GO:0031720 haptoglobin binding(GO:0031720)
8.8 44.0 GO:1990932 5.8S rRNA binding(GO:1990932)
8.7 8.7 GO:0042296 ISG15 transferase activity(GO:0042296)
8.7 34.8 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
8.7 43.5 GO:0005550 pheromone binding(GO:0005550)
8.6 34.6 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
8.6 25.9 GO:0042806 fucose binding(GO:0042806)
8.6 42.8 GO:0004854 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
8.5 25.6 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
8.5 67.7 GO:0032052 bile acid binding(GO:0032052)
8.3 58.2 GO:0001849 complement component C1q binding(GO:0001849)
8.2 73.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
8.2 48.9 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
7.9 23.8 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
7.9 158.2 GO:0005537 mannose binding(GO:0005537)
7.9 94.8 GO:0001848 complement binding(GO:0001848)
7.8 38.8 GO:0071987 WD40-repeat domain binding(GO:0071987)
7.8 23.3 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
7.8 62.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
7.5 30.1 GO:0016019 peptidoglycan receptor activity(GO:0016019)
7.5 60.0 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
7.3 29.4 GO:0004771 sterol esterase activity(GO:0004771)
7.3 36.6 GO:0004974 leukotriene receptor activity(GO:0004974)
7.3 29.1 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829)
7.2 14.4 GO:0004743 pyruvate kinase activity(GO:0004743)
7.2 28.8 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
7.1 7.1 GO:0050294 steroid sulfotransferase activity(GO:0050294)
7.1 91.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
7.0 41.9 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
6.9 83.2 GO:0048406 nerve growth factor binding(GO:0048406)
6.9 13.9 GO:0050051 leukotriene-B4 20-monooxygenase activity(GO:0050051) tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871)
6.9 41.3 GO:0071723 lipopeptide binding(GO:0071723)
6.8 47.4 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
6.7 26.9 GO:0015057 thrombin receptor activity(GO:0015057)
6.7 26.8 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
6.7 20.0 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
6.7 746.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
6.7 20.0 GO:0019961 interferon binding(GO:0019961)
6.6 6.6 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
6.6 46.2 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
6.5 71.8 GO:0008131 primary amine oxidase activity(GO:0008131)
6.5 117.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
6.4 45.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
6.4 44.8 GO:0003896 DNA primase activity(GO:0003896)
6.3 100.8 GO:0019825 oxygen binding(GO:0019825)
6.3 1372.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
6.3 62.9 GO:0004950 chemokine receptor activity(GO:0004950)
6.3 43.9 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
6.3 18.8 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
6.2 458.9 GO:0003823 antigen binding(GO:0003823)
6.2 43.3 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
6.2 6.2 GO:0004645 phosphorylase activity(GO:0004645)
6.2 36.9 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
6.0 30.2 GO:0016841 ammonia-lyase activity(GO:0016841)
6.0 30.2 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
6.0 30.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
6.0 23.8 GO:0004967 glucagon receptor activity(GO:0004967)
5.9 11.8 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
5.9 17.7 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
5.9 64.6 GO:0070513 death domain binding(GO:0070513)
5.9 17.6 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
5.7 17.0 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
5.6 16.8 GO:0016414 carnitine O-octanoyltransferase activity(GO:0008458) O-octanoyltransferase activity(GO:0016414)
5.5 27.5 GO:0070087 chromo shadow domain binding(GO:0070087)
5.5 44.0 GO:0045545 syndecan binding(GO:0045545)
5.5 71.4 GO:0008097 5S rRNA binding(GO:0008097)
5.5 16.5 GO:0030626 U12 snRNA binding(GO:0030626)
5.5 27.3 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
5.4 10.8 GO:0036310 annealing helicase activity(GO:0036310)
5.4 194.0 GO:0005044 scavenger receptor activity(GO:0005044)
5.4 5.4 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
5.3 21.4 GO:0005534 galactose binding(GO:0005534)
5.3 132.7 GO:0070330 aromatase activity(GO:0070330)
5.3 21.1 GO:0004903 growth hormone receptor activity(GO:0004903)
5.3 15.8 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
5.3 31.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
5.2 78.4 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
5.2 196.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
5.1 5.1 GO:0045340 mercury ion binding(GO:0045340)
5.1 25.4 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
5.1 10.2 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
5.1 5.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
5.0 5.0 GO:0004040 amidase activity(GO:0004040)
5.0 10.0 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
5.0 39.7 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
5.0 34.7 GO:0004064 arylesterase activity(GO:0004064)
5.0 29.7 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
5.0 14.9 GO:0070835 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) nickel cation transmembrane transporter activity(GO:0015099) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) chromium ion transmembrane transporter activity(GO:0070835)
4.9 14.8 GO:0008142 oxysterol binding(GO:0008142)
4.9 24.7 GO:0005138 interleukin-6 receptor binding(GO:0005138)
4.9 19.7 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
4.9 44.0 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
4.9 29.3 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
4.9 19.5 GO:0005143 interleukin-12 receptor binding(GO:0005143)
4.8 14.5 GO:0000991 transcription factor activity, core RNA polymerase II binding(GO:0000991)
4.8 14.5 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508)
4.7 14.2 GO:0032810 sterol response element binding(GO:0032810)
4.7 4.7 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
4.7 9.4 GO:0008384 IkappaB kinase activity(GO:0008384)
4.6 9.3 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
4.6 9.2 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
4.6 13.7 GO:0031762 follicle-stimulating hormone receptor binding(GO:0031762)
4.6 22.9 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
4.5 13.6 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
4.5 36.1 GO:0004875 complement receptor activity(GO:0004875)
4.5 67.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
4.5 4.5 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
4.5 8.9 GO:0034185 apolipoprotein binding(GO:0034185)
4.4 13.3 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
4.4 13.3 GO:0004924 oncostatin-M receptor activity(GO:0004924)
4.4 8.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
4.4 17.6 GO:0005131 growth hormone receptor binding(GO:0005131)
4.4 30.7 GO:1990446 U1 snRNP binding(GO:1990446)
4.4 8.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
4.3 17.2 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
4.3 21.4 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
4.3 8.5 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
4.2 12.7 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
4.2 16.9 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
4.2 29.1 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
4.1 53.4 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
4.1 16.4 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
4.1 24.5 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
4.1 8.1 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
4.1 1098.8 GO:0030246 carbohydrate binding(GO:0030246)
4.1 8.1 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
4.0 24.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
4.0 56.5 GO:0008301 DNA binding, bending(GO:0008301)
4.0 12.0 GO:0000403 Y-form DNA binding(GO:0000403)
4.0 20.0 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
4.0 15.9 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
4.0 8.0 GO:0031893 vasopressin receptor binding(GO:0031893)
3.9 31.6 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
3.9 19.7 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
3.9 11.7 GO:0009384 N-acylmannosamine kinase activity(GO:0009384)
3.9 27.3 GO:0030151 molybdenum ion binding(GO:0030151)
3.9 23.2 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
3.9 15.5 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
3.8 49.9 GO:0045125 bioactive lipid receptor activity(GO:0045125)
3.8 15.1 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
3.8 959.4 GO:0003735 structural constituent of ribosome(GO:0003735)
3.8 18.8 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
3.7 3.7 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
3.7 14.9 GO:0070568 guanylyltransferase activity(GO:0070568)
3.7 25.9 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
3.7 22.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
3.7 51.1 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
3.6 65.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
3.6 21.7 GO:0009008 DNA-methyltransferase activity(GO:0009008)
3.6 17.9 GO:0001054 RNA polymerase I activity(GO:0001054)
3.5 21.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
3.5 10.5 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
3.4 20.6 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
3.4 13.7 GO:0042608 T cell receptor binding(GO:0042608)
3.4 54.5 GO:0008199 ferric iron binding(GO:0008199)
3.4 27.2 GO:0019864 IgG binding(GO:0019864)
3.4 10.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
3.4 37.3 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
3.4 16.9 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
3.4 13.5 GO:0004920 interleukin-10 receptor activity(GO:0004920)
3.3 20.0 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
3.3 55.4 GO:0043295 glutathione binding(GO:0043295)
3.3 9.8 GO:0004536 deoxyribonuclease activity(GO:0004536)
3.2 6.5 GO:0046977 TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
3.2 29.2 GO:0015232 heme transporter activity(GO:0015232)
3.2 22.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
3.2 54.8 GO:0004745 retinol dehydrogenase activity(GO:0004745)
3.2 16.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
3.1 12.5 GO:0030350 iron-responsive element binding(GO:0030350)
3.1 24.9 GO:0001055 RNA polymerase II activity(GO:0001055)
3.1 24.9 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
3.1 9.3 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
3.1 3.1 GO:0004519 endonuclease activity(GO:0004519)
3.1 33.9 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
3.1 55.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
3.1 58.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
3.0 6.1 GO:0002060 purine nucleobase binding(GO:0002060)
3.0 9.1 GO:1903924 estradiol binding(GO:1903924)
3.0 12.0 GO:0097100 supercoiled DNA binding(GO:0097100)
3.0 9.0 GO:0017113 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydrouracil dehydrogenase (NAD+) activity(GO:0004159) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
3.0 60.0 GO:0017127 cholesterol transporter activity(GO:0017127)
3.0 119.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
3.0 12.0 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
3.0 6.0 GO:0070012 oligopeptidase activity(GO:0070012)
3.0 47.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
3.0 26.7 GO:0043515 kinetochore binding(GO:0043515)
3.0 11.8 GO:0030280 structural constituent of epidermis(GO:0030280)
2.9 20.6 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
2.9 14.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
2.9 8.8 GO:0034057 RNA strand-exchange activity(GO:0034057)
2.9 5.9 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
2.9 8.7 GO:0042134 rRNA primary transcript binding(GO:0042134)
2.9 11.5 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
2.9 17.3 GO:0042954 lipoprotein transporter activity(GO:0042954)
2.9 20.1 GO:0008432 JUN kinase binding(GO:0008432)
2.9 8.6 GO:0004046 aminoacylase activity(GO:0004046)
2.8 2.8 GO:0032405 MutLalpha complex binding(GO:0032405)
2.8 14.0 GO:1990226 histone methyltransferase binding(GO:1990226)
2.8 5.6 GO:0033592 RNA strand annealing activity(GO:0033592)
2.8 27.7 GO:0004526 ribonuclease P activity(GO:0004526)
2.7 46.4 GO:0001594 trace-amine receptor activity(GO:0001594)
2.7 5.5 GO:0031686 A1 adenosine receptor binding(GO:0031686)
2.7 27.3 GO:0008061 chitin binding(GO:0008061)
2.7 10.9 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
2.7 10.9 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
2.7 10.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
2.7 13.5 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
2.7 489.2 GO:0042393 histone binding(GO:0042393)
2.7 72.5 GO:0016849 cyclase activity(GO:0009975) phosphorus-oxygen lyase activity(GO:0016849)
2.7 21.4 GO:0042609 CD4 receptor binding(GO:0042609)
2.7 18.6 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
2.6 7.9 GO:0009041 uridylate kinase activity(GO:0009041)
2.6 42.3 GO:0004806 triglyceride lipase activity(GO:0004806)
2.6 10.6 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
2.6 10.5 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
2.6 26.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
2.6 31.4 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
2.6 7.8 GO:0070698 type I activin receptor binding(GO:0070698)
2.6 59.5 GO:0008009 chemokine activity(GO:0008009)
2.6 7.7 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
2.6 20.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
2.6 7.7 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
2.5 7.6 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
2.5 20.3 GO:0042301 phosphate ion binding(GO:0042301)
2.5 1018.4 GO:0005549 odorant binding(GO:0005549)
2.5 20.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
2.5 7.5 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
2.5 35.1 GO:0019104 DNA N-glycosylase activity(GO:0019104)
2.5 7.5 GO:0003922 GMP synthase activity(GO:0003921) GMP synthase (glutamine-hydrolyzing) activity(GO:0003922)
2.5 19.8 GO:0016004 phospholipase activator activity(GO:0016004)
2.5 105.5 GO:0004896 cytokine receptor activity(GO:0004896)
2.5 9.8 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
2.4 129.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
2.4 224.6 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
2.4 14.6 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
2.4 14.4 GO:0070051 fibrinogen binding(GO:0070051)
2.4 38.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
2.4 9.6 GO:0000293 ferric-chelate reductase activity(GO:0000293)
2.4 9.5 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
2.4 16.6 GO:0030621 U4 snRNA binding(GO:0030621)
2.4 9.5 GO:1990955 G-rich single-stranded DNA binding(GO:1990955)
2.4 9.4 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
2.3 4.7 GO:0004335 galactokinase activity(GO:0004335)
2.3 25.6 GO:0070182 DNA polymerase binding(GO:0070182)
2.3 58.0 GO:0001784 phosphotyrosine binding(GO:0001784)
2.3 9.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
2.3 18.3 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
2.3 4.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
2.3 16.0 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
2.3 29.7 GO:0003796 lysozyme activity(GO:0003796)
2.3 6.8 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
2.2 22.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
2.2 11.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
2.2 8.9 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
2.2 108.5 GO:0003684 damaged DNA binding(GO:0003684)
2.2 11.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
2.2 15.5 GO:0004957 prostaglandin E receptor activity(GO:0004957)
2.2 4.4 GO:0048408 epidermal growth factor binding(GO:0048408)
2.2 2.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
2.2 13.2 GO:0004953 icosanoid receptor activity(GO:0004953)
2.2 54.6 GO:0004364 glutathione transferase activity(GO:0004364)
2.2 8.7 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
2.2 6.5 GO:0004655 porphobilinogen synthase activity(GO:0004655)
2.2 15.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
2.2 10.8 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
2.1 19.0 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
2.1 14.7 GO:0061133 endopeptidase activator activity(GO:0061133)
2.1 22.9 GO:0032036 myosin heavy chain binding(GO:0032036)
2.1 8.3 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
2.1 2.1 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546)
2.1 6.2 GO:0016015 morphogen activity(GO:0016015)
2.1 24.6 GO:0008143 poly(A) binding(GO:0008143)
2.0 4.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
2.0 8.2 GO:0034584 piRNA binding(GO:0034584)
2.0 10.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
2.0 10.1 GO:0005148 prolactin receptor binding(GO:0005148)
2.0 34.3 GO:0015288 porin activity(GO:0015288)
2.0 6.0 GO:0016748 succinyltransferase activity(GO:0016748)
2.0 10.0 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
2.0 4.0 GO:0051425 PTB domain binding(GO:0051425)
2.0 41.6 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
2.0 7.9 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
2.0 1738.8 GO:0004984 olfactory receptor activity(GO:0004984)
2.0 7.8 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
2.0 7.8 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
1.9 7.8 GO:0043199 sulfate binding(GO:0043199)
1.9 3.9 GO:0004370 glycerol kinase activity(GO:0004370)
1.9 11.6 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
1.9 28.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
1.9 51.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
1.9 5.7 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
1.9 3.8 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
1.9 9.5 GO:0004301 epoxide hydrolase activity(GO:0004301)
1.9 3.7 GO:0001007 transcription factor activity, RNA polymerase III transcription factor binding(GO:0001007)
1.9 5.6 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
1.9 7.4 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
1.9 9.3 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
1.9 18.5 GO:0042162 telomeric DNA binding(GO:0042162)
1.8 1.8 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
1.8 9.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
1.8 3.7 GO:0019237 centromeric DNA binding(GO:0019237)
1.8 160.4 GO:0004540 ribonuclease activity(GO:0004540)
1.8 10.8 GO:0070728 leucine binding(GO:0070728)
1.8 19.8 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
1.8 9.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
1.8 12.5 GO:0047134 protein-disulfide reductase activity(GO:0047134)
1.8 14.3 GO:0009881 photoreceptor activity(GO:0009881)
1.8 7.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
1.8 10.6 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
1.8 12.3 GO:0051525 NFAT protein binding(GO:0051525)
1.7 29.7 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
1.7 17.5 GO:0038024 cargo receptor activity(GO:0038024)
1.7 15.6 GO:0003746 translation elongation factor activity(GO:0003746)
1.7 278.1 GO:0001047 core promoter binding(GO:0001047)
1.7 3.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
1.7 55.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
1.7 39.7 GO:0004623 phospholipase A2 activity(GO:0004623)
1.7 20.5 GO:0045294 alpha-catenin binding(GO:0045294)
1.7 8.5 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
1.7 5.1 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
1.7 33.9 GO:0004601 peroxidase activity(GO:0004601)
1.7 8.5 GO:1990459 transferrin receptor binding(GO:1990459)
1.7 13.3 GO:0052834 inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
1.7 5.0 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
1.7 5.0 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
1.7 10.0 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
1.7 11.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
1.6 6.6 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
1.6 16.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
1.6 3.2 GO:0045322 unmethylated CpG binding(GO:0045322)
1.6 9.6 GO:0004994 somatostatin receptor activity(GO:0004994)
1.6 14.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
1.6 3.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
1.6 6.4 GO:0003987 acetate-CoA ligase activity(GO:0003987)
1.6 26.8 GO:0019843 rRNA binding(GO:0019843)
1.6 23.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
1.6 4.7 GO:0004774 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775)
1.5 15.4 GO:0008641 small protein activating enzyme activity(GO:0008641)
1.5 12.2 GO:0008430 selenium binding(GO:0008430)
1.5 4.6 GO:0031711 bradykinin receptor binding(GO:0031711)
1.5 12.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
1.5 6.0 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
1.5 6.0 GO:0043024 ribosomal small subunit binding(GO:0043024)
1.5 22.4 GO:0004697 protein kinase C activity(GO:0004697)
1.5 4.5 GO:0046790 virion binding(GO:0046790)
1.5 7.4 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
1.5 25.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
1.5 8.8 GO:0004126 cytidine deaminase activity(GO:0004126)
1.4 20.0 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
1.4 57.5 GO:0000049 tRNA binding(GO:0000049)
1.4 8.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
1.4 4.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
1.4 5.5 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
1.4 13.8 GO:0005000 vasopressin receptor activity(GO:0005000)
1.4 19.3 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
1.4 48.3 GO:0003727 single-stranded RNA binding(GO:0003727)
1.4 6.9 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
1.4 4.1 GO:0016722 oxidoreductase activity, oxidizing metal ions(GO:0016722)
1.4 2.7 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
1.4 2.7 GO:0033142 progesterone receptor binding(GO:0033142)
1.4 6.8 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
1.3 13.5 GO:0070410 co-SMAD binding(GO:0070410)
1.3 6.7 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
1.3 4.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
1.3 5.3 GO:0019002 GMP binding(GO:0019002)
1.3 3.9 GO:0008506 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
1.3 10.5 GO:1901611 phosphatidylglycerol binding(GO:1901611)
1.3 3.9 GO:0015252 hydrogen ion channel activity(GO:0015252)
1.3 32.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
1.3 78.4 GO:0031490 chromatin DNA binding(GO:0031490)
1.3 6.4 GO:0031849 olfactory receptor binding(GO:0031849)
1.3 2.5 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
1.2 2.5 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
1.2 5.0 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
1.2 19.5 GO:0043274 phospholipase binding(GO:0043274)
1.2 2.4 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
1.2 16.7 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
1.2 3.6 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
1.2 4.7 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.2 5.8 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
1.2 5.8 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
1.2 6.9 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
1.1 26.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
1.1 15.7 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
1.1 5.6 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
1.1 1.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
1.1 9.9 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
1.1 1.1 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
1.1 17.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
1.1 5.5 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
1.1 22.9 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
1.1 17.4 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
1.1 15.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
1.1 7.6 GO:0016778 diphosphotransferase activity(GO:0016778)
1.1 3.2 GO:0031765 galanin receptor binding(GO:0031763) type 2 galanin receptor binding(GO:0031765) type 3 galanin receptor binding(GO:0031766)
1.1 3.2 GO:0048019 receptor antagonist activity(GO:0048019)
1.1 10.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
1.1 2.1 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
1.1 11.7 GO:0030414 peptidase inhibitor activity(GO:0030414)
1.1 77.4 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
1.1 10.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
1.0 5.2 GO:0050733 RS domain binding(GO:0050733)
1.0 2.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
1.0 10.4 GO:0051400 BH domain binding(GO:0051400)
1.0 3.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
1.0 45.7 GO:0033613 activating transcription factor binding(GO:0033613)
1.0 3.1 GO:0042809 vitamin D receptor binding(GO:0042809)
1.0 2.1 GO:0019865 immunoglobulin binding(GO:0019865)
1.0 3.1 GO:0035596 methylthiotransferase activity(GO:0035596) transferase activity, transferring alkylthio groups(GO:0050497)
1.0 59.1 GO:0003743 translation initiation factor activity(GO:0003743)
1.0 7.1 GO:0001056 RNA polymerase III activity(GO:0001056)
1.0 6.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
1.0 9.0 GO:0051428 peptide hormone receptor binding(GO:0051428)
1.0 4.0 GO:0001972 retinoic acid binding(GO:0001972)
1.0 2.0 GO:0032190 acrosin binding(GO:0032190)
1.0 1.0 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
1.0 25.3 GO:0030515 snoRNA binding(GO:0030515)
1.0 4.8 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
1.0 26.1 GO:0008527 taste receptor activity(GO:0008527)
1.0 17.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
1.0 3.8 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.9 6.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.9 2.8 GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.9 3.7 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.9 1.8 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.9 9.0 GO:0035586 purinergic receptor activity(GO:0035586)
0.9 15.3 GO:0017025 TBP-class protein binding(GO:0017025)
0.9 8.8 GO:0003678 DNA helicase activity(GO:0003678)
0.9 0.9 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.9 1.7 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.9 11.2 GO:0070063 RNA polymerase binding(GO:0070063)
0.9 3.4 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.8 1.7 GO:0038100 nodal binding(GO:0038100)
0.8 2.5 GO:0051990 (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.8 41.4 GO:0020037 heme binding(GO:0020037)
0.8 1.7 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.8 2.5 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.8 11.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.8 9.8 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.8 4.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.8 3.2 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.8 2.4 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.8 5.6 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.8 3.9 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.8 6.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.8 2.3 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.8 1.5 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.8 23.4 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.8 15.1 GO:0071889 14-3-3 protein binding(GO:0071889)
0.7 1.5 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.7 23.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.7 11.4 GO:0070001 aspartic-type peptidase activity(GO:0070001)
0.7 2.8 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.7 3.4 GO:0005499 vitamin D binding(GO:0005499)
0.7 2.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.7 2.0 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.7 1.3 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.7 7.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.7 1.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.7 4.6 GO:0050700 CARD domain binding(GO:0050700)
0.7 2.0 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.6 3.9 GO:0070888 E-box binding(GO:0070888)
0.6 1.9 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.6 3.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.6 7.5 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.6 2.5 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.6 4.9 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.6 7.9 GO:0004527 exonuclease activity(GO:0004527)
0.6 1.8 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.6 3.0 GO:0046965 retinoid X receptor binding(GO:0046965)
0.6 7.6 GO:0019789 SUMO transferase activity(GO:0019789)
0.6 5.2 GO:0035497 cAMP response element binding(GO:0035497)
0.6 5.7 GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.6 31.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.5 2.7 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.5 3.8 GO:0034711 inhibin binding(GO:0034711)
0.5 3.8 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.5 2.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.5 2.7 GO:0070034 telomerase RNA binding(GO:0070034)
0.5 12.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.5 3.0 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.5 2.5 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.5 1.5 GO:0008502 melatonin receptor activity(GO:0008502)
0.5 3.0 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.5 1.5 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.5 1.5 GO:0004827 proline-tRNA ligase activity(GO:0004827)
0.5 84.4 GO:0003682 chromatin binding(GO:0003682)
0.5 4.7 GO:0051766 inositol trisphosphate kinase activity(GO:0051766)
0.5 164.3 GO:0005525 GTP binding(GO:0005525)
0.5 1.9 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.5 6.0 GO:0071837 HMG box domain binding(GO:0071837)
0.5 2.7 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.4 22.0 GO:0008026 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.4 1.8 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.4 5.2 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.4 2.1 GO:0004849 uridine kinase activity(GO:0004849)
0.4 5.0 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.4 1.2 GO:0015203 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.4 2.4 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.4 3.6 GO:0019841 retinol binding(GO:0019841)
0.4 107.5 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.4 4.4 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.4 1.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.4 2.4 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.4 6.3 GO:0008536 Ran GTPase binding(GO:0008536)
0.4 3.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.4 1.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.4 5.3 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.4 1.1 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.4 0.4 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.3 0.3 GO:0015929 hexosaminidase activity(GO:0015929)
0.3 280.8 GO:0003677 DNA binding(GO:0003677)
0.3 0.7 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.3 0.9 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.3 0.6 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.3 4.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.3 1.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.3 2.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 0.8 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2 1.0 GO:0030172 troponin C binding(GO:0030172)
0.2 0.5 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.2 0.7 GO:0035198 miRNA binding(GO:0035198)
0.2 1.2 GO:0004969 histamine receptor activity(GO:0004969)
0.2 2.3 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.2 4.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.2 0.5 GO:0016289 CoA hydrolase activity(GO:0016289)
0.2 4.1 GO:0016209 antioxidant activity(GO:0016209)
0.2 0.6 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.2 0.6 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.2 0.4 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.2 2.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.2 0.8 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.2 0.6 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.2 1.8 GO:0032794 GTPase activating protein binding(GO:0032794)
0.2 1.0 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 0.4 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.2 2.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 0.8 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.2 1.0 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.2 2.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 0.5 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.2 1.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 3.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 4.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 0.4 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.5 GO:0050308 carbohydrate phosphatase activity(GO:0019203) sugar-phosphatase activity(GO:0050308)
0.1 2.2 GO:0008373 sialyltransferase activity(GO:0008373)
0.1 1.6 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 3.0 GO:0002039 p53 binding(GO:0002039)
0.1 0.7 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.5 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 1.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.3 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 0.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.2 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.0 0.1 GO:0031770 growth hormone-releasing hormone receptor binding(GO:0031770)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.2 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.5 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.0 GO:0004127 cytidylate kinase activity(GO:0004127)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
17.7 35.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
12.0 23.9 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
11.6 360.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
10.4 146.0 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
9.1 598.5 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
8.8 157.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
8.1 48.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
7.6 45.4 PID CD40 PATHWAY CD40/CD40L signaling
7.2 43.2 PID IL5 PATHWAY IL5-mediated signaling events
6.1 194.9 PID IL23 PATHWAY IL23-mediated signaling events
5.8 193.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
5.3 85.5 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
5.0 248.4 PID BCR 5PATHWAY BCR signaling pathway
5.0 14.9 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
4.9 38.9 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
4.7 51.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
4.6 129.5 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
4.5 116.5 PID IL1 PATHWAY IL1-mediated signaling events
4.5 147.5 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
4.3 234.9 PID FANCONI PATHWAY Fanconi anemia pathway
4.1 8.2 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
4.0 177.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
3.9 109.7 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
3.9 260.7 PID CMYB PATHWAY C-MYB transcription factor network
3.8 61.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
3.6 39.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
3.3 165.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
3.2 25.6 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
3.1 83.8 PID IL4 2PATHWAY IL4-mediated signaling events
3.1 156.7 PID E2F PATHWAY E2F transcription factor network
3.1 702.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
3.0 12.0 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
2.9 34.7 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
2.8 33.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
2.7 65.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
2.7 103.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
2.7 103.4 PID AURORA B PATHWAY Aurora B signaling
2.7 54.4 PID IL12 2PATHWAY IL12-mediated signaling events
2.7 64.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
2.6 18.0 PID ENDOTHELIN PATHWAY Endothelins
2.4 29.3 PID BARD1 PATHWAY BARD1 signaling events
2.4 9.8 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
2.4 56.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
2.2 15.4 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
2.2 48.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
2.2 107.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
2.1 2.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
2.1 27.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
2.0 34.8 PID TCPTP PATHWAY Signaling events mediated by TCPTP
1.9 29.8 PID IL6 7 PATHWAY IL6-mediated signaling events
1.9 9.3 PID ATR PATHWAY ATR signaling pathway
1.9 7.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
1.8 30.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
1.7 28.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
1.7 31.9 PID TXA2PATHWAY Thromboxane A2 receptor signaling
1.6 11.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
1.5 10.6 PID EPO PATHWAY EPO signaling pathway
1.4 2.9 PID MYC PATHWAY C-MYC pathway
1.4 54.0 PID RAC1 PATHWAY RAC1 signaling pathway
1.4 24.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
1.4 53.3 PID PLK1 PATHWAY PLK1 signaling events
1.2 6.1 PID FOXO PATHWAY FoxO family signaling
1.2 5.9 PID PI3KCI PATHWAY Class I PI3K signaling events
1.1 12.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
1.1 64.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
1.0 8.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
1.0 16.0 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
1.0 2.9 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.9 20.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.9 6.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.8 1.7 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.8 6.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.8 31.0 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.7 4.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.7 106.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.7 22.1 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.7 21.0 PID TELOMERASE PATHWAY Regulation of Telomerase
0.7 5.9 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.6 27.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.6 36.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.6 9.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.6 24.1 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.6 11.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.6 1.2 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.6 3.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.5 3.8 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.5 11.0 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.5 4.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.5 1.0 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.5 118.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.4 10.8 PID RHOA PATHWAY RhoA signaling pathway
0.4 0.9 PID IL27 PATHWAY IL27-mediated signaling events
0.4 2.9 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.4 0.8 PID IFNG PATHWAY IFN-gamma pathway
0.4 5.0 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.3 2.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.3 3.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 1.0 ST GAQ PATHWAY G alpha q Pathway
0.2 3.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 5.4 PID P53 REGULATION PATHWAY p53 pathway
0.2 1.0 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 1.0 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 3.2 PID P73PATHWAY p73 transcription factor network
0.1 1.1 PID ATM PATHWAY ATM pathway
0.0 0.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.6 PID MTOR 4PATHWAY mTOR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
24.0 192.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
19.6 117.7 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
18.8 847.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
16.5 313.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
16.3 146.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
16.0 64.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
13.7 82.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
12.0 191.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
11.4 377.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
11.4 91.1 REACTOME DEFENSINS Genes involved in Defensins
10.6 158.9 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
10.4 124.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
10.1 474.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
8.9 151.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
8.7 52.0 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
8.2 131.9 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
7.6 84.0 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
7.4 191.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
7.3 138.6 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
7.1 120.1 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
6.7 87.0 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
6.6 125.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
6.5 71.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
6.4 19.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
6.4 44.8 REACTOME POL SWITCHING Genes involved in Polymerase switching
6.3 75.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
6.2 67.9 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
6.2 117.2 REACTOME TCR SIGNALING Genes involved in TCR signaling
6.0 89.4 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
5.9 153.8 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
5.8 46.7 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
5.6 83.3 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
5.5 87.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
5.4 130.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
5.4 101.8 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
5.0 34.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
4.9 9.8 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
4.9 48.8 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
4.8 38.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
4.7 32.6 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
4.5 443.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
4.4 62.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
4.4 308.3 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
4.3 43.1 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
4.2 46.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
4.2 4.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
4.2 58.5 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
4.2 45.9 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
4.2 99.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
4.1 28.5 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
4.0 68.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
3.9 23.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
3.8 11.4 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
3.8 234.3 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
3.8 18.8 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
3.8 63.8 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
3.7 29.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
3.7 291.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
3.7 3.7 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
3.5 38.6 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
3.5 171.0 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
3.4 63.9 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
3.3 32.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
3.3 39.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
3.1 120.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
2.9 17.1 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
2.8 2.8 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
2.8 16.8 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
2.8 58.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
2.8 55.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
2.8 47.0 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
2.6 2.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
2.6 89.1 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
2.5 27.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
2.5 69.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
2.4 2.4 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
2.4 46.2 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
2.4 26.0 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
2.3 37.3 REACTOME AMYLOIDS Genes involved in Amyloids
2.2 4.5 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
2.2 33.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
2.2 2.2 REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION Genes involved in Incretin Synthesis, Secretion, and Inactivation
2.1 10.7 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
2.1 2.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
2.1 50.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
2.0 55.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
2.0 19.6 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
1.9 15.0 REACTOME OPSINS Genes involved in Opsins
1.9 5.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
1.8 32.9 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
1.8 18.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
1.8 37.7 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
1.8 23.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
1.8 3.6 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
1.7 25.0 REACTOME SIGNALING BY ILS Genes involved in Signaling by Interleukins
1.6 12.8 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
1.6 22.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
1.6 53.6 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
1.5 3.1 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
1.5 33.8 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
1.5 21.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
1.5 197.7 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
1.5 1.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
1.5 7.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
1.5 44.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
1.4 4.3 REACTOME SIGNALING BY WNT Genes involved in Signaling by Wnt
1.4 19.8 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
1.4 15.5 REACTOME G1 PHASE Genes involved in G1 Phase
1.4 82.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
1.4 5.5 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
1.3 5.3 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
1.3 38.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
1.3 23.7 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
1.3 11.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
1.3 6.4 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
1.3 44.1 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
1.3 25.1 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
1.2 5.0 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
1.2 33.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
1.2 5.8 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
1.1 20.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
1.0 17.8 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
1.0 40.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
1.0 8.2 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
1.0 29.4 REACTOME TRANSLATION Genes involved in Translation
1.0 88.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
1.0 12.7 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
1.0 8.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.9 0.9 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.9 21.6 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.9 12.7 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.9 12.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.8 11.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.8 12.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.8 25.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.8 17.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.7 6.1 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.6 9.7 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.6 19.2 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.6 3.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.6 7.9 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.5 1.1 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.5 2.6 REACTOME CHROMOSOME MAINTENANCE Genes involved in Chromosome Maintenance
0.5 7.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.5 7.9 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.5 12.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.4 3.8 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.4 3.6 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.4 8.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.4 19.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.4 2.2 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.3 2.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.3 4.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.3 1.1 REACTOME CELL CYCLE CHECKPOINTS Genes involved in Cell Cycle Checkpoints
0.3 2.9 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.2 5.4 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.2 3.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.2 0.9 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.2 3.1 REACTOME DNA REPAIR Genes involved in DNA Repair
0.2 3.8 REACTOME HIV LIFE CYCLE Genes involved in HIV Life Cycle
0.2 1.7 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 1.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.2 1.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.2 2.3 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 8.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.4 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.1 2.8 REACTOME RNA POL III TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.1 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants