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GSE53960: rat RNA-Seq transcriptomic Bodymap
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Results for Foxf2
Z-value: 0.86
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Transcription factors associated with Foxf2
| Gene Symbol | Gene ID | Gene Info |
|---|
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr13_+_89597138 Show fit | 56.37 |
ENSRNOT00000004662
|
apolipoprotein A2 |
|
| chr18_-_24929091 Show fit | 44.51 |
ENSRNOT00000019596
|
protein C |
|
| chr10_+_56662242 Show fit | 43.62 |
ENSRNOT00000086919
|
asialoglycoprotein receptor 1 |
|
| chr8_-_115981910 Show fit | 42.42 |
ENSRNOT00000019867
|
dedicator of cyto-kinesis 3 |
|
| chr11_-_81660395 Show fit | 32.96 |
ENSRNOT00000048739
|
fetuin B |
|
| chr3_-_101474890 Show fit | 32.70 |
ENSRNOT00000091869
|
gamma-butyrobetaine hydroxylase 1 |
|
| chr2_-_182035032 Show fit | 32.63 |
ENSRNOT00000009813
|
fibrinogen beta chain |
|
| chr18_+_59748444 Show fit | 32.60 |
ENSRNOT00000024752
|
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
|
| chr7_-_119689938 Show fit | 32.13 |
ENSRNOT00000000200
|
transmembrane protease, serine 6 |
|
| chr7_+_93975451 Show fit | 29.99 |
ENSRNOT00000011379
|
collectin subfamily member 10 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Foxf2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 18.8 | 56.4 | GO:0010903 | negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) diacylglycerol catabolic process(GO:0046340) |
| 7.4 | 44.5 | GO:1903142 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
| 0.1 | 43.6 | GO:0031668 | cellular response to extracellular stimulus(GO:0031668) |
| 6.0 | 35.9 | GO:0001705 | ectoderm formation(GO:0001705) |
| 4.4 | 35.0 | GO:0018231 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 5.4 | 32.7 | GO:0045329 | carnitine biosynthetic process(GO:0045329) |
| 10.9 | 32.6 | GO:1990743 | protein sialylation(GO:1990743) |
| 6.5 | 32.6 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 2.9 | 32.1 | GO:0097264 | self proteolysis(GO:0097264) |
| 2.7 | 29.9 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.3 | 56.4 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
| 0.1 | 52.0 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 0.1 | 48.9 | GO:0014069 | postsynaptic density(GO:0014069) |
| 0.0 | 39.4 | GO:0005783 | endoplasmic reticulum(GO:0005783) |
| 1.2 | 35.0 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 4.1 | 32.6 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.7 | 32.6 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.4 | 30.0 | GO:0005581 | collagen trimer(GO:0005581) |
| 4.3 | 29.9 | GO:0005579 | membrane attack complex(GO:0005579) |
| 1.5 | 23.3 | GO:0070852 | cell body fiber(GO:0070852) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 18.8 | 56.4 | GO:0070653 | high-density lipoprotein particle receptor binding(GO:0070653) |
| 0.2 | 45.4 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
| 14.8 | 44.5 | GO:0070012 | oligopeptidase activity(GO:0070012) |
| 0.2 | 35.7 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 5.0 | 35.0 | GO:0097001 | ceramide binding(GO:0097001) |
| 2.7 | 33.0 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.7 | 32.7 | GO:0016706 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706) |
| 10.9 | 32.6 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 1.5 | 30.0 | GO:0005537 | mannose binding(GO:0005537) |
| 0.3 | 30.0 | GO:0051087 | chaperone binding(GO:0051087) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.5 | 77.1 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.4 | 55.5 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.3 | 16.0 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.7 | 10.9 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.1 | 5.6 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.1 | 3.6 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 3.5 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.2 | 2.9 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.0 | 2.7 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.1 | 1.9 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.8 | 77.1 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 3.3 | 56.4 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 1.4 | 38.4 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 1.9 | 32.6 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.2 | 31.1 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.9 | 29.9 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 0.5 | 26.2 | REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 1.7 | 25.8 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
| 0.8 | 23.3 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.2 | 21.3 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |