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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Foxc1

Z-value: 0.86

Motif logo

Transcription factors associated with Foxc1

Gene Symbol Gene ID Gene Info
ENSRNOG00000017800 forkhead box C1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxc1rn6_v1_chr17_-_33951484_339514840.115.3e-02Click!

Activity profile of Foxc1 motif

Sorted Z-values of Foxc1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_215610368 31.41 ENSRNOT00000078903
ENSRNOT00000087781
troponin I2, fast skeletal type
chr10_+_53781239 30.28 ENSRNOT00000082871
myosin heavy chain 2
chr1_+_215609645 24.95 ENSRNOT00000076140
ENSRNOT00000027487
troponin I2, fast skeletal type
chr10_+_53713938 22.43 ENSRNOT00000004236
ENSRNOT00000086599
ENSRNOT00000085582
myosin heavy chain 2
chr2_+_60131776 21.82 ENSRNOT00000080786
prolactin receptor
chr16_+_25773602 18.91 ENSRNOT00000047750
glyceraldehyde-3-phosphate dehydrogenase, pseudogene 2
chr10_+_59725398 18.33 ENSRNOT00000026156
purinergic receptor P2X 5
chr7_-_113937941 17.86 ENSRNOT00000012408
potassium two pore domain channel subfamily K member 9
chr11_-_72109964 17.82 ENSRNOT00000058917

chr5_+_115649046 16.12 ENSRNOT00000041328
glyceraldehyde-3-phosphate dehydrogenase
chr10_-_102289837 15.39 ENSRNOT00000044922

chr1_-_253000760 14.10 ENSRNOT00000030024
solute carrier family 16, member 12
chr8_+_100260049 14.09 ENSRNOT00000011090

chr16_+_16949232 13.83 ENSRNOT00000047499

chr13_-_103080920 13.71 ENSRNOT00000034990

chr16_+_26906716 13.02 ENSRNOT00000064297
carboxypeptidase E
chr7_-_49250953 12.52 ENSRNOT00000066975
ENSRNOT00000082141
acyl-CoA synthetase short-chain family member 3
chr2_+_95077577 12.45 ENSRNOT00000046368
mitochondrial ribosomal protein S28
chr1_+_193537137 12.01 ENSRNOT00000029967

chr6_+_64297888 11.88 ENSRNOT00000050222
ENSRNOT00000083088
ENSRNOT00000093147
neuronal cell adhesion molecule
chr1_-_82452281 11.83 ENSRNOT00000027995
branched chain ketoacid dehydrogenase E1, alpha polypeptide
chr12_-_5773036 11.74 ENSRNOT00000041365
FRY microtubule binding protein
chr3_-_160301552 11.42 ENSRNOT00000014498
regulating synaptic membrane exocytosis 4
chr17_-_84614228 11.36 ENSRNOT00000043042

chr10_+_56662242 11.06 ENSRNOT00000086919
asialoglycoprotein receptor 1
chr14_+_37116492 10.81 ENSRNOT00000002921
sarcoglycan, beta
chr10_+_56662561 10.47 ENSRNOT00000025254
asialoglycoprotein receptor 1
chr1_+_101625790 10.45 ENSRNOT00000029220
MEF2 activating motif and SAP domain containing transcriptional regulator
chr18_-_71614980 9.92 ENSRNOT00000032563
peroxisomal biogenesis factor 19-like
chr8_-_109560747 9.83 ENSRNOT00000087334
protein phosphatase 2, regulatory subunit B'', alpha
chr11_-_64952687 9.56 ENSRNOT00000087892
popeye domain containing 2
chr20_-_45126062 9.40 ENSRNOT00000000720
similar to KIAA1919 protein
chrX_+_142344878 8.78 ENSRNOT00000056621
high mobility group protein B4-like
chr10_-_84698886 8.50 ENSRNOT00000067542
nuclear factor, erythroid 2-like 1
chr13_+_56262190 8.33 ENSRNOT00000032908

chr14_-_19132208 8.27 ENSRNOT00000060535
afamin
chr13_+_52667969 8.25 ENSRNOT00000084986
ENSRNOT00000050284
troponin T2, cardiac type
chr9_+_52023295 8.17 ENSRNOT00000004956
collagen type III alpha 1 chain
chr3_+_9643047 8.16 ENSRNOT00000035805
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr13_-_111972603 8.08 ENSRNOT00000007870
hydroxysteroid 11-beta dehydrogenase 1
chr1_-_258877045 7.98 ENSRNOT00000071633
cytochrome P450, family 2, subfamily c, polypeptide 13
chr3_+_60024013 7.93 ENSRNOT00000025255
secernin 3
chr1_+_150067242 7.72 ENSRNOT00000073824
olfactory receptor 23
chr1_-_251379593 7.55 ENSRNOT00000014684
ATPase family, AAA domain containing 1
chr10_-_98544447 7.18 ENSRNOT00000073149
ATP binding cassette subfamily A member 6
chr14_-_14689554 6.90 ENSRNOT00000002814
Fraser extracellular matrix complex subunit 1
chr2_+_84678948 6.86 ENSRNOT00000046325
family with sequence similarity 173, member B
chr18_-_35817117 6.29 ENSRNOT00000015172
ENSRNOT00000085714
mutated in colorectal cancers
chr19_+_50246402 6.29 ENSRNOT00000018795
hydroxysteroid (17-beta) dehydrogenase 2
chr2_-_96032722 6.20 ENSRNOT00000015746
proteasome subunit beta type 6-like
chr3_-_75089064 6.17 ENSRNOT00000046167
olfactory receptor 542
chr8_-_39266959 5.87 ENSRNOT00000046590
EI24, autophagy associated transmembrane protein
chr7_-_144269486 5.59 ENSRNOT00000090051
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr3_-_91195981 5.47 ENSRNOT00000056935
similar to RIKEN cDNA B230118H07
chr6_+_64252970 5.45 ENSRNOT00000093700
patatin-like phospholipase domain containing 8
chr10_+_13196946 5.37 ENSRNOT00000071525
protease, serine, 32
chr16_-_79973735 5.25 ENSRNOT00000057845
ENSRNOT00000086896
DLG associated protein 2
chr2_-_258997138 5.11 ENSRNOT00000045020
ENSRNOT00000042256
adhesion G protein-coupled receptor L2
chr11_+_28692708 4.93 ENSRNOT00000002135
keratin associated protein 13-1
chr3_+_122544788 4.83 ENSRNOT00000063828
transglutaminase 3
chr4_+_72292261 4.64 ENSRNOT00000078723
olfactory receptor-like protein OLF3
chr16_-_7758189 4.61 ENSRNOT00000026588
2-hydroxyacyl-CoA lyase 1
chr3_-_77710180 4.57 ENSRNOT00000087015
olfactory receptor 671
chr15_-_33263659 4.53 ENSRNOT00000018005
proteasome subunit beta 5
chr10_-_78690857 4.50 ENSRNOT00000089255
similar to glyceraldehyde-3-phosphate dehydrogenase
chr4_+_158243086 4.47 ENSRNOT00000032112
anoctamin 2
chr20_-_9855443 4.41 ENSRNOT00000090275
ENSRNOT00000066266
trefoil factor 3
chrX_+_75382598 4.30 ENSRNOT00000033494
uracil phosphoribosyltransferase homolog
chr2_-_235232530 4.23 ENSRNOT00000093386
ENSRNOT00000079943
leucine-rich repeat, Ig-like and transmembrane domains 3
chr11_-_34598102 4.23 ENSRNOT00000068743
phosphatidylinositol glycan anchor biosynthesis, class P
chr2_-_197981665 4.22 ENSRNOT00000083086
mitochondrial ribosomal protein S21
chrX_+_71342775 4.14 ENSRNOT00000004888
integrin subunit beta 1 binding protein 2
chr8_+_22625874 4.11 ENSRNOT00000012269
translocase of inner mitochondrial membrane 29
chr3_+_114253637 4.03 ENSRNOT00000046843
dual oxidase 1
chr1_+_149963547 3.95 ENSRNOT00000042245
olfactory receptor 20
chr10_+_88992487 3.93 ENSRNOT00000027061
Coenzyme A synthase
chr8_+_57936650 3.79 ENSRNOT00000089686
exophilin 5
chr3_-_21027947 3.79 ENSRNOT00000051973
olfactory receptor 421
chr2_+_112914375 3.64 ENSRNOT00000092737
neutral cholesterol ester hydrolase 1
chr1_+_70480941 3.61 ENSRNOT00000072404
olfactory receptor 6
chr12_+_19513100 3.58 ENSRNOT00000030161
similar to family with sequence similarity 55, member C
chr5_-_105579959 3.48 ENSRNOT00000010827
solute carrier family 24 member 2
chr1_+_230628996 3.46 ENSRNOT00000017604
olfactory receptor 376
chr1_-_226732736 3.33 ENSRNOT00000072343
pepsin F-like
chr3_+_128756799 3.27 ENSRNOT00000049855
ENSRNOT00000042853
phospholipase C, beta 4
chr15_-_32925673 3.26 ENSRNOT00000081045
olfactory receptor 1646
chr13_-_86671515 3.22 ENSRNOT00000082869

chr1_-_70485888 3.22 ENSRNOT00000020514
olfactory receptor 7
chr2_+_77084222 3.20 ENSRNOT00000087171
predicted gene 9733
chr10_-_39622973 3.20 ENSRNOT00000031762
interleukin 3
chr12_+_19512591 3.07 ENSRNOT00000060024
similar to family with sequence similarity 55, member C
chr8_-_36876931 3.01 ENSRNOT00000073753
prostate and testis expressed 1
chr1_+_150130084 2.95 ENSRNOT00000041243
olfactory receptor 25
chr5_+_76092287 2.90 ENSRNOT00000020207
zinc finger protein 483
chr18_+_56379890 2.89 ENSRNOT00000078764
platelet derived growth factor receptor beta
chr9_-_26734763 2.75 ENSRNOT00000082814

chr7_+_121480723 2.74 ENSRNOT00000065304
activating transcription factor 4
chr3_-_79165698 2.70 ENSRNOT00000032617
olfactory receptor 744
chr1_-_172322795 2.69 ENSRNOT00000075318
similar to olfactory receptor MOR204-14
chr5_+_137564607 2.66 ENSRNOT00000075742
olfactory receptor 2B6-like
chr8_+_43355060 2.64 ENSRNOT00000043206
olfactory receptor 1309
chr1_+_44311513 2.60 ENSRNOT00000065386
T-cell lymphoma invasion and metastasis 2
chr5_+_87354042 2.57 ENSRNOT00000068178
interferon alpha-12-like
chr15_-_29993639 2.55 ENSRNOT00000071822

chr5_+_136406130 2.50 ENSRNOT00000093099
ERI1 exoribonuclease family member 3
chr9_-_71798265 2.50 ENSRNOT00000043766
crystallin, gamma B
chr12_-_2568382 2.43 ENSRNOT00000035142
leucine rich repeat containing 8 family, member E
chr1_+_258074860 2.38 ENSRNOT00000054729
cytochrome P450, family 2, subfamily c, polypeptide 24
chr3_+_43255567 2.19 ENSRNOT00000044419
glycerol-3-phosphate dehydrogenase 2
chr1_-_261669584 2.19 ENSRNOT00000020568
ENSRNOT00000076555
cartilage acidic protein 1
chr4_+_72221550 2.11 ENSRNOT00000078533
olfactory receptor 806
chr7_+_13996966 2.05 ENSRNOT00000009615
olfactory receptor 1087
chr5_+_118574801 2.04 ENSRNOT00000035949
ubiquitin-conjugating enzyme E2U (putative)
chr1_+_27476375 1.84 ENSRNOT00000047224
ENSRNOT00000075427
sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2-like
chr10_-_12236107 1.83 ENSRNOT00000049390
olfactory receptor 1381
chr5_+_15043955 1.80 ENSRNOT00000047093
retinitis pigmentosa 1
chr10_-_12370656 1.80 ENSRNOT00000060995
olfactory receptor 1362
chr10_-_71491743 1.77 ENSRNOT00000038955
uncharacterized LOC102552988
chr3_-_162579201 1.76 ENSRNOT00000068328
zinc finger, MYND-type containing 8
chr1_+_16819170 1.74 ENSRNOT00000019734
ENSRNOT00000086756
HBS1-like translational GTPase
chr18_+_30375798 1.73 ENSRNOT00000060497
protocadherin beta 2
chr3_-_20914603 1.67 ENSRNOT00000049651
olfactory receptor 416
chr3_-_76289390 1.66 ENSRNOT00000051968
olfactory receptor 609
chr1_+_150225373 1.65 ENSRNOT00000051266
olfactory receptor 30
chr5_+_137775801 1.63 ENSRNOT00000074907
similar to olfactory receptor 1340
chr10_+_34402482 1.54 ENSRNOT00000072317
putative olfactory receptor
chr3_+_176865156 1.52 ENSRNOT00000019084
zinc finger CCCH-type and G-patch domain containing
chr20_+_1781320 1.44 ENSRNOT00000040388
olfactory receptor 1737
chr10_-_38969501 1.42 ENSRNOT00000090691
ENSRNOT00000081309
ENSRNOT00000010029
interleukin 4
chr7_-_144959746 1.39 ENSRNOT00000064261
zinc finger protein 385A
chr12_-_19439977 1.36 ENSRNOT00000060035
neurexophilin and PC-esterase domain family, member 5
chr2_-_178616719 1.35 ENSRNOT00000078610
transmembrane protein 144
chr8_+_59457018 1.34 ENSRNOT00000017900
iron responsive element binding protein 2
chr1_-_22480522 1.32 ENSRNOT00000046379
trace-amine-associated receptor 7e
chr8_-_22625959 1.32 ENSRNOT00000012138
Yip1 domain family, member 2
chr17_-_77261731 1.27 ENSRNOT00000066850
upper zone of growth plate and cartilage matrix associated
chr5_-_78285451 1.25 ENSRNOT00000019924
ring finger protein 183
chr10_-_12522230 1.23 ENSRNOT00000073401
olfactory receptor 1370
chr14_-_37763712 1.21 ENSRNOT00000030610
zygote arrest 1
chr17_+_25228437 1.17 ENSRNOT00000072904

chr16_+_35573058 1.09 ENSRNOT00000059580
polypeptide N-acetylgalactosaminyltransferase-like 6
chr10_-_12777245 1.08 ENSRNOT00000041708
olfactory receptor 1380
chr20_-_795286 1.04 ENSRNOT00000052186
olfactory receptor 1691
chr20_+_1322453 1.00 ENSRNOT00000075472
olfactory receptor 1868
chr9_-_23454316 0.95 ENSRNOT00000072826
cytochrome P450, family 2, subfamily ac, polypeptide 1
chr7_-_117068332 0.94 ENSRNOT00000082433
family with sequence similarity 83, member H
chr8_+_117282390 0.89 ENSRNOT00000074772
ubiquitin specific peptidase 19
chr15_-_29680444 0.89 ENSRNOT00000075008

chr8_+_43382176 0.84 ENSRNOT00000047759
olfactory receptor 1311
chr2_-_248484100 0.82 ENSRNOT00000040856
guanylate binding protein 3
chr3_+_78835929 0.80 ENSRNOT00000008762
olfactory receptor 725
chr5_+_107233230 0.74 ENSRNOT00000029976
interferon, epsilon
chr1_-_44615760 0.73 ENSRNOT00000022148
NADPH oxidase 3
chr1_-_175895510 0.68 ENSRNOT00000064535
eukaryotic translation initiation factor 4, gamma 2
chr18_+_29951094 0.64 ENSRNOT00000027402
protocadherin alpha-1-like
chr14_+_71533063 0.60 ENSRNOT00000004231
prominin 1
chr15_-_37926715 0.59 ENSRNOT00000013901
exportin 4
chr13_-_35668968 0.59 ENSRNOT00000042862
ENSRNOT00000003428
erythrocyte membrane protein band 4.1 like 5
chr3_-_112876773 0.52 ENSRNOT00000015086
ubiquitin protein ligase E3 component n-recognin 1
chr5_-_50138475 0.37 ENSRNOT00000011969
solute carrier family 35 member A1
chr11_+_44001579 0.35 ENSRNOT00000002258
G protein-coupled receptor 15
chr8_+_40410604 0.26 ENSRNOT00000049392
olfactory receptor 1202
chr9_+_42620006 0.10 ENSRNOT00000019966
heparan sulfate 6-O-sulfotransferase 1
chr12_-_40332612 0.08 ENSRNOT00000001691
ataxin 2
chr5_-_154394023 0.08 ENSRNOT00000079823
ribosomal protein L11
chrX_-_82699487 0.04 ENSRNOT00000081625
ribosomal protein S6 kinase A6
chr14_-_70160624 0.01 ENSRNOT00000022589
clarin 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxc1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.4 16.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
4.1 52.7 GO:0001778 plasma membrane repair(GO:0001778)
3.3 9.8 GO:0090249 cell motility involved in somitogenic axis elongation(GO:0090247) regulation of cell motility involved in somitogenic axis elongation(GO:0090249)
3.2 9.6 GO:0060931 sinoatrial node cell development(GO:0060931)
2.9 11.7 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
2.7 8.2 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
2.7 8.2 GO:0006480 N-terminal protein amino acid methylation(GO:0006480) peptidyl-glycine modification(GO:0018201)
2.7 8.1 GO:0006713 glucocorticoid catabolic process(GO:0006713)
2.6 13.0 GO:0030070 insulin processing(GO:0030070) negative regulation of branching morphogenesis of a nerve(GO:2000173)
2.4 21.8 GO:0038161 prolactin signaling pathway(GO:0038161)
2.0 8.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
1.7 18.3 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
1.4 5.5 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
1.3 4.0 GO:0042335 cuticle development(GO:0042335)
1.3 11.9 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
1.1 56.4 GO:0003009 skeletal muscle contraction(GO:0003009)
1.1 10.8 GO:0097084 vascular smooth muscle cell development(GO:0097084)
1.0 2.9 GO:0038086 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.9 2.7 GO:1990737 negative regulation of translational initiation in response to stress(GO:0032057) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.8 11.8 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.8 3.2 GO:0033026 negative regulation of mast cell apoptotic process(GO:0033026) mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.8 4.6 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.7 6.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.7 5.9 GO:0071494 cellular response to UV-C(GO:0071494)
0.6 4.3 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.5 2.5 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.5 5.3 GO:0046710 GDP metabolic process(GO:0046710)
0.5 1.4 GO:2000422 T-helper 1 cell lineage commitment(GO:0002296) negative regulation of complement-dependent cytotoxicity(GO:1903660) regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
0.4 14.1 GO:0072337 modified amino acid transport(GO:0072337)
0.4 1.8 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.4 2.2 GO:0019563 glycerol catabolic process(GO:0019563)
0.4 3.8 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.4 7.6 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.4 2.5 GO:0000459 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.3 1.4 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.3 8.0 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.3 10.4 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.3 3.3 GO:0033139 regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141) serine phosphorylation of STAT protein(GO:0042501)
0.3 11.4 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.3 4.8 GO:0031424 keratinization(GO:0031424)
0.2 3.9 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.2 2.4 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.2 0.6 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.2 5.6 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 6.9 GO:0003338 metanephros morphogenesis(GO:0003338)
0.2 1.8 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.2 2.2 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.2 4.2 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.2 0.6 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.1 3.3 GO:0007602 phototransduction(GO:0007602)
0.1 1.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 1.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.1 3.4 GO:0051180 vitamin transport(GO:0051180)
0.1 0.7 GO:0048840 otolith development(GO:0048840)
0.1 0.5 GO:0071233 cellular response to leucine(GO:0071233)
0.1 3.5 GO:0060292 long term synaptic depression(GO:0060292)
0.1 21.5 GO:0031668 cellular response to extracellular stimulus(GO:0031668)
0.1 8.5 GO:0030218 erythrocyte differentiation(GO:0030218)
0.1 3.6 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.1 0.9 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.1 5.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 5.4 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.1 66.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 1.4 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 8.9 GO:0006006 glucose metabolic process(GO:0006006)
0.0 0.6 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 4.5 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 10.2 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 4.1 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 1.3 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 7.2 GO:0006869 lipid transport(GO:0006869)
0.0 1.8 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.9 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 1.7 GO:0007416 synapse assembly(GO:0007416)
0.0 0.9 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.1 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 6.6 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)
0.0 0.7 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 3.3 GO:0006914 autophagy(GO:0006914)
0.0 0.3 GO:0072678 T cell migration(GO:0072678)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.9 52.7 GO:0005826 actomyosin contractile ring(GO:0005826)
5.4 64.6 GO:0005861 troponin complex(GO:0005861)
2.4 11.8 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
2.0 16.1 GO:0097452 GAIT complex(GO:0097452)
1.8 10.8 GO:0016012 sarcoglycan complex(GO:0016012)
1.0 18.3 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.9 2.7 GO:1990589 Lewy body core(GO:1990037) ATF4-CREB1 transcription factor complex(GO:1990589) ATF1-ATF4 transcription factor complex(GO:1990590)
0.8 13.0 GO:0031045 dense core granule(GO:0031045)
0.7 8.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.6 16.7 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.5 2.0 GO:0033503 HULC complex(GO:0033503)
0.5 4.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.4 10.7 GO:0005839 proteasome core complex(GO:0005839)
0.4 11.9 GO:0043194 axon initial segment(GO:0043194)
0.4 2.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.4 5.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.4 9.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.3 5.3 GO:0005883 neurofilament(GO:0005883)
0.2 11.4 GO:0048786 presynaptic active zone(GO:0048786)
0.2 0.6 GO:0071914 prominosome(GO:0071914)
0.1 1.8 GO:0097542 ciliary tip(GO:0097542)
0.1 23.5 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 0.7 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 8.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 3.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 13.4 GO:0008021 synaptic vesicle(GO:0008021)
0.1 13.9 GO:0030427 site of polarized growth(GO:0030427)
0.1 6.9 GO:0005604 basement membrane(GO:0005604)
0.1 4.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 9.6 GO:0042383 sarcolemma(GO:0042383)
0.0 3.0 GO:0030018 Z disc(GO:0030018)
0.0 2.9 GO:0072562 blood microparticle(GO:0072562)
0.0 1.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.2 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 3.9 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.9 GO:0045095 keratin filament(GO:0045095)
0.0 8.2 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.5 GO:0000502 proteasome complex(GO:0000502)
0.0 66.4 GO:0016021 integral component of membrane(GO:0016021)
0.0 0.6 GO:0005643 nuclear pore(GO:0005643)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.1 56.4 GO:0031014 troponin T binding(GO:0031014)
7.3 21.8 GO:0004925 prolactin receptor activity(GO:0004925)
4.1 8.2 GO:0030172 troponin C binding(GO:0030172)
4.0 16.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
2.7 8.2 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
2.7 8.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
2.0 18.3 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
1.5 4.6 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
1.3 11.9 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
1.3 11.8 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
1.2 13.0 GO:0050897 cobalt ion binding(GO:0050897)
1.2 5.9 GO:0061676 importin-alpha family protein binding(GO:0061676)
1.1 3.2 GO:0005135 interleukin-3 receptor binding(GO:0005135)
1.0 2.9 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.9 6.3 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.9 3.5 GO:0016151 nickel cation binding(GO:0016151)
0.9 4.3 GO:0004849 uridine kinase activity(GO:0004849)
0.8 3.9 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.7 8.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.7 2.2 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.7 14.1 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.7 4.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.7 5.5 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.6 7.9 GO:0016805 dipeptidase activity(GO:0016805)
0.5 5.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.5 4.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.5 7.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.4 4.0 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.4 10.7 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.4 1.4 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.3 10.4 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.3 1.3 GO:0030350 iron-responsive element binding(GO:0030350)
0.3 3.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.3 5.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.3 21.5 GO:0038024 cargo receptor activity(GO:0038024)
0.3 3.6 GO:0042301 phosphate ion binding(GO:0042301)
0.2 9.6 GO:0030552 cAMP binding(GO:0030552)
0.2 4.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.2 8.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2 0.9 GO:1990254 keratin filament binding(GO:1990254)
0.2 16.7 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 3.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 3.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 1.9 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 4.5 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.1 2.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.7 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.1 46.5 GO:0003779 actin binding(GO:0003779)
0.1 0.9 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 10.3 GO:0044325 ion channel binding(GO:0044325)
0.1 0.5 GO:0070728 leucine binding(GO:0070728)
0.1 1.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 9.3 GO:0030674 protein binding, bridging(GO:0030674)
0.1 1.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 1.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 27.4 GO:0005549 odorant binding(GO:0005549)
0.1 10.4 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.1 7.2 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 39.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 3.4 GO:0019842 vitamin binding(GO:0019842)
0.0 4.1 GO:0005178 integrin binding(GO:0005178)
0.0 1.7 GO:1901476 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 3.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 2.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 11.1 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.0 5.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.6 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 3.3 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 52.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.4 21.8 PID ERBB4 PATHWAY ErbB4 signaling events
0.2 13.0 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.2 3.2 PID IL3 PATHWAY IL3-mediated signaling events
0.2 8.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.2 2.9 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 3.5 PID CONE PATHWAY Visual signal transduction: Cones
0.1 5.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 3.3 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 2.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 6.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 4.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 64.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
1.4 17.9 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
1.0 21.8 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.7 11.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.5 13.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.4 7.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.3 11.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 3.9 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 4.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.2 5.5 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.2 1.9 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 8.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 3.2 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 4.5 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.1 3.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 3.3 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 2.9 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 2.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 3.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.1 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 2.2 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism